GO:0030199

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Name collagen fibril organization
Categary Process
Go Slim No
Go Link GO:0030199
Unique Molecular Interactions 336
Total Molecular Interactions 401
Total Single Events 4468
Pain Genes Associated 38

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for collagen fibril organization. They are ordered first by their pain relevance and then by number of times they were reported for collagen fibril organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65
2 INT157460 CX3CL1 Regulation of Gene_expression of COL1A1 1 0.11 1.57 1.37
3 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
4 INT204551 Binding of Col2a1 and Positive_regulation of Cia1 1 0.03 1.74 1.03
5 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
6 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
7 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
8 INT222988 TNF Positive_regulation of Protein_catabolism of COL1A1 1 0.01 1.66 0.9
9 INT135781 Cyp3a23/3a1 Positive_regulation of Positive_regulation of Col1a1 1 0.01 0.78 0.8
10 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
11 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
12 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
13 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
14 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
15 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
16 INT353978 Lmx1b Regulation of Gene_expression of Pet1 1 0.31 0.21 0.53
17 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
18 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52
19 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
20 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
21 INT72089 TGFB2 Positive_regulation of POMC 1 0.11 0 0.46
22 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
23 INT320810 Protein_catabolism of COL1A2 Positive_regulation of Localization of CYP27A1 1 0.04 1.05 0.4
24 INT160245 Binding of Col11a1 and Crygs 1 0.00 0.17 0.4
25 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
26 INT198970 GAPDH Negative_regulation of ADAMTS3 1 0.47 0 0.35
27 INT254344 Binding of Col2a1 and Ncoa5 1 0.00 0.98 0.35
28 INT209312 Trpc5 Positive_regulation of Gene_expression of Scx 1 0.15 0.05 0.33
29 INT149896 Ihh Regulation of Gene_expression of Col1a1 1 0.06 0.89 0.33
30 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
31 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32
32 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32
33 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3
34 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3
35 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
36 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3
37 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29
38 INT328224 Col2a1 Positive_regulation of Gene_expression of Mmp13 1 0.04 0.8 0.29
39 INT179838 Col3a1 Regulation of Negative_regulation of Il11 1 0.21 0 0.29
40 INT302467 TIMP1 Positive_regulation of Negative_regulation of COL5A2 1 0.00 1.1 0.29
41 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
42 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
43 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28
44 INT137014 Positive_regulation of Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
45 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
46 INT137012 Pscs Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
47 INT214594 Binding of FOXC1 and IBD9 1 0.00 1.81 0.28
48 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
49 INT109538 Lox Negative_regulation of Transcription of VEGFA 1 0.30 0.69 0.26
50 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
51 INT109539 Lox Negative_regulation of VEGFA 1 0.40 0.68 0.25
52 INT271446 Thy1 Regulation of Col1a1 1 0.05 0.61 0.25
53 INT252784 ROS1 Positive_regulation of Gene_expression of COL1A1 1 0.05 1.86 0.24
54 INT266006 Binding of COL5A2 and SGCG 1 0.00 0.89 0.23
55 INT353981 Gene_expression of Pet1 Positive_regulation of Lmx1b 1 0.53 0 0.23
56 INT115875 Col5a1 Positive_regulation of Localization of Gcg 1 0.08 0 0.23
57 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
58 INT285639 Col3a1 Regulation of Tnfrsf12a 1 0.19 0.16 0.22
59 INT173558 CTSK Positive_regulation of Protein_catabolism of COL5A2 1 0.00 0.53 0.22
60 INT316810 Sparc Regulation of Col1a1 1 0.13 0.48 0.21
61 INT353285 Prdx2 Regulation of Gene_expression of Col1a2 1 0.02 0.73 0.21
62 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
63 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
64 INT225099 ZNF630 Positive_regulation of Gene_expression of COL1A1 1 0.00 0.17 0.2
65 INT255516 Binding of COL5A2 and GP6 1 0.01 1.17 0.2
66 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
67 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
68 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18
69 INT220191 Binding of COL2A1 and PTGER2 1 0.22 0.35 0.18
70 INT103197 Nf1 Negative_regulation of ras 1 0.04 1.19 0.17
71 INT346305 Binding of ELANE and Col2a1 1 0.00 0.98 0.17
72 INT191615 Binding of Nf1 and Flna 1 0.08 0.53 0.17
73 INT191621 Binding of Drd3 and Nf1 1 0.32 0.53 0.17
74 INT271444 Binding of Lox and Eln 1 0.21 0.82 0.16
75 INT323803 NFAT5 Positive_regulation of Regulation of COL5A2 1 0.07 0.46 0.16
76 INT185793 SPP1 Positive_regulation of COL1A2 1 0.16 0.33 0.16
77 INT323805 NFAT5 Regulation of COL5A2 1 0.07 0.46 0.16
78 INT103198 NF1 Negative_regulation of ras 1 0.05 1.19 0.16
79 INT264868 Binding of COL1A2 and GOPC 1 0.02 0.3 0.15
80 INT336337 Glp2r Positive_regulation of Gene_expression of Col2a1 1 0.01 0.7 0.14
81 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14
82 INT309779 PTH Negative_regulation of Gene_expression of COL5A2 1 0.00 0.52 0.14
83 INT116382 Lox Positive_regulation of Binding of Alox5 1 0.12 0.25 0.14
84 INT180960 Protein_catabolism of COL5A2 Positive_regulation of Positive_regulation of NPEPPS 1 0.00 0.59 0.14
85 INT180963 COL5A2 Positive_regulation of Positive_regulation of NPEPPS 1 0.00 0.59 0.14
86 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
87 INT65269 Igf1 Positive_regulation of Gene_expression of Lox 1 0.15 0 0.14
88 INT214593 Binding of FOXC1 and OAP 1 0.01 0.25 0.13
89 INT65267 Igf1 Regulation of Gene_expression of Plod3 1 0.07 0 0.13
90 INT65271 Igf1 Positive_regulation of Gene_expression of Plod3 1 0.12 0 0.13
91 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13
92 INT316813 Sparc Negative_regulation of Gene_expression of Col1a1 1 0.13 0.67 0.12
93 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
94 INT266003 Binding of COL5A2 and DIO3 1 0.01 0.43 0.11
95 INT133362 FABP6 Negative_regulation of LOX 1 0.01 0.08 0.11
96 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11
97 INT323869 Binding of BMI1 and COL1A2 1 0.00 1.21 0.11
98 INT327405 Lox Positive_regulation of Ptk2 1 0.42 1.3 0.1
99 INT294445 KLK4 Negative_regulation of COL1A1 1 0.01 0 0.1
100 INT205055 MMP3 Negative_regulation of COL1A2 1 0.32 1.52 0.1
101 INT149178 IL4 Negative_regulation of Positive_regulation of TGFB2 1 0.15 0.29 0.1
102 INT179869 COL1A1 Positive_regulation of SOCS3 1 0.04 0.99 0.1
103 INT207459 LGALS3 Regulation of Gene_expression of COL1A2 1 0.06 0.21 0.1
104 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09
105 INT323868 LEP Regulation of Transcription of COL1A2 1 0.10 0.98 0.09
106 INT294608 Binding of Serpinh1 and Col5a1 1 0.03 0.45 0.09
107 INT346304 Col2a1 Positive_regulation of Localization of PTGER2 1 0.00 0.18 0.09
108 INT58630 Calca Negative_regulation of Positive_regulation of COL1A1 1 0.02 0.23 0.08
109 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08
110 INT336425 MGAT1 Positive_regulation of Gene_expression of COL5A2 1 0.00 0.4 0.08
111 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
112 INT323876 LEP Regulation of COL1A2 1 0.10 0.86 0.08
113 INT222983 TNF Positive_regulation of Positive_regulation of COL1A1 1 0.01 0.71 0.08
114 INT218710 MMP1 Regulation of Positive_regulation of Col1a1 1 0.00 0.15 0.07
115 INT277053 Protein_catabolism of TIMP1 Positive_regulation of COL5A2 1 0.01 0.14 0.07
116 INT288003 Binding of COL2A1 and PADI1 1 0.09 0.11 0.06
117 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
118 INT304331 Binding of COL5A2 and TGFBI 1 0.01 0.38 0.06
119 INT242475 Ciapin1 Positive_regulation of Gene_expression of Anxa2 1 0.01 1.13 0.06
120 INT255512 Binding of COL5A2 and CRP 1 0.01 0 0.06
121 INT346302 ELANE Regulation of Col2a1 1 0.00 0.3 0.05
122 INT257343 Lox Regulation of Cyba 1 0.02 0.37 0.05
123 INT180668 Edn1 Positive_regulation of Gene_expression of Col1a1 1 0.02 0 0.05
124 INT220081 Binding of COL1A1 and MMRN1 1 0.00 0.36 0.05
125 INT220189 Binding of COL2A1 and TIMP1 1 0.04 0.1 0.05
126 INT257338 Lox Regulation of Cybb 1 0.00 0.37 0.05
127 INT346280 Binding of COL5A2 and PTK2 1 0.01 0.1 0.05
128 INT257339 Lox Regulation of Ncf1 1 0.02 0.37 0.05
129 INT346283 Binding of COL11A1 and ELANE 1 0.01 0.08 0.04
130 INT323807 NFAT5 Regulation of Gene_expression of COL2A1 1 0.29 0.19 0.04
131 INT346303 Binding of MR1 and Col2a1 1 0.00 0.09 0.04
132 INT179840 Binding of Col3a1 and Sparc 1 0.25 0 0.04
133 INT220196 Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1 1 0.26 0.77 0.04
134 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
135 INT222980 TNF Positive_regulation of Localization of COL1A1 1 0.01 0.56 0.04
136 INT271449 Binding of TGFB1 and Lox 1 0.01 0.38 0.04
137 INT199526 Ceacam1 Negative_regulation of Col1a1 1 0.01 0.06 0.03
138 INT337727 ADAMTS2 Positive_regulation of Gene_expression of KIT 1 0.02 0 0.03
139 INT261727 TNF Regulation of COL5A2 1 0.05 0.21 0.03
140 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03
141 INT172892 Negative_regulation of Lox Negative_regulation of Gene_expression of Mcl1 1 0.06 1.13 0.03
142 INT172909 Cpox Regulation of Lox 1 0.03 0.51 0.03
143 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
144 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
145 INT337751 ADAMTS2 Positive_regulation of Gene_expression of Nkx6-1 1 0.04 0 0.03
146 INT261731 PSMB6 Regulation of COL5A2 1 0.00 0.21 0.03
147 INT220245 IL1RN Regulation of Protein_catabolism of COL2A1 1 0.09 0 0.03
148 INT172897 Negative_regulation of Lox Positive_regulation of Positive_regulation of Casp3 1 0.04 1.19 0.03
149 INT222977 Positive_regulation of COL1A1 Positive_regulation of MMP1 1 0.01 0.61 0.03
150 INT180954 PASK Regulation of COL5A2 1 0.00 0.7 0.03
151 INT312346 FUT1 Positive_regulation of Gene_expression of COL11A1 1 0.17 1.02 0.03
152 INT172910 Lox Positive_regulation of Positive_regulation of Casp3 1 0.03 1.19 0.03
153 INT222987 Positive_regulation of COL1A1 Positive_regulation of Protein_catabolism of MMP1 1 0.01 0.61 0.03
154 INT172896 Lox Negative_regulation of Gene_expression of Mcl1 1 0.05 1.13 0.03
155 INT337737 ADAMTS2 Positive_regulation of Gene_expression of PDX1 1 0.02 0 0.03
156 INT261733 F2 Regulation of COL5A2 1 0.03 0.21 0.03
157 INT170329 Binding of Col4a1 and Col1a1 1 0.03 0.14 0.03
158 INT180565 HEYL Positive_regulation of Negative_regulation of COL1A1 1 0.01 0 0.03
159 INT180571 HEYL Positive_regulation of Protein_catabolism of COL1A1 1 0.01 0 0.03
160 INT172894 Negative_regulation of Lox Negative_regulation of Gene_expression of Bcl2 1 0.03 1.12 0.03
161 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
162 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03
163 INT170331 Binding of Col7a1 and Col1a1 1 0.00 0.14 0.03
164 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
165 INT337728 ADAMTS2 Positive_regulation of Gene_expression of INS 1 0.02 0 0.03
166 INT172900 Binding of Cpox and Lox 1 0.02 0.4 0.03
167 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
168 INT252820 ELANE Positive_regulation of Gene_expression of COL1A1 1 0.01 0.58 0
169 INT312224 INPP5K Regulation of Negative_regulation of COL1A1 1 0.08 0 0
170 INT337735 ADAMTS2 Positive_regulation of Gene_expression of GCK 1 0.01 0 0
171 INT261729 COL5A2 Regulation of Gene_expression of F2R 1 0.18 0 0
172 INT267117 Lmx1b Regulation of Col7a1 1 0.02 1.29 0
173 INT189929 Lox Positive_regulation of Pol 1 0.02 0.34 0
174 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0
175 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
176 INT180862 Binding of ANXA2 and S100A10 1 0.17 0.82 0
177 INT337733 ADAMTS2 Positive_regulation of Gene_expression of GK 1 0.00 0 0
178 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0
179 INT35137 SPANXC Positive_regulation of Negative_regulation of SERPINF2 1 0.00 0 0
180 INT252796 ELANE Regulation of COL1A1 1 0.01 0.57 0
181 INT244846 Lbx1 Positive_regulation of Lmx1b 1 0.40 0 0
182 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
183 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0
184 INT180847 Binding of COL1A1 and NID2 1 0.05 0.91 0
185 INT245731 Binding of COL5A2 and DISC1 1 0.01 0.42 0
186 INT288002 Binding of COL2A1 and GOPC 1 0.12 0 0
187 INT269248 Lox Negative_regulation of Ptk2 1 0.24 1.02 0
188 INT63391 SLTM Regulation of Gene_expression of Col2a1 1 0.00 0 0
189 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
190 INT314862 Binding of Ltbp3 and Tgfb2 1 0.24 0.52 0
191 INT184210 IL1B Negative_regulation of Gene_expression of COL1A2 1 0.04 0 0
192 INT189556 Binding of COL5A2 and SPARCL1 1 0.00 1.22 0
193 INT189551 Binding of COL5A2 and DCN 1 0.00 0.72 0
194 INT267115 Lmx1b Regulation of Gene_expression of Col4a1 1 0.09 1.37 0
195 INT312214 INPP5K Regulation of Gene_expression of COL1A1 1 0.08 0 0
196 INT316811 Negative_regulation of Col1a2 Negative_regulation of Col3a1 1 0.33 0.07 0
197 INT261734 COL5A2 Regulation of Gene_expression of ACTB 1 0.17 0 0
198 INT252773 ROS1 Positive_regulation of COL1A1 1 0.05 0.57 0
199 INT347257 Binding of LOX and PPARA 1 0.15 0.6 0
200 INT185848 Binding of COL11A2 and NTNG2 1 0.13 1.06 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for collagen fibril organization. They are ordered first by their pain relevance and then by number of times they were reported in collagen fibril organization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58
2 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15
3 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44
4 INT90673 Gene_expression of LOX 66 0.65 69.71 12.18
5 INT37618 Gene_expression of Col2a1 50 0.70 33.88 11.58
6 INT94004 Negative_regulation of Lox 31 0.59 13.76 10.45
7 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41
8 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28
9 INT173587 Protein_catabolism of COL5A2 59 0.32 32.73 8.96
10 INT90674 Negative_regulation of LOX 56 0.57 38.01 8.58
11 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29
12 INT81608 Gene_expression of Col11a1 13 0.15 1.58 6.87
13 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98
14 INT65262 Gene_expression of Lox 47 0.74 36.59 5.65
15 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48
16 INT89142 Gene_expression of Lox 28 0.67 15.36 5.2
17 INT123422 Gene_expression of Lmx1b 18 0.78 6.93 5.17
18 INT84561 Binding of COL1A2 18 0.47 11.76 5.09
19 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81
20 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77
21 INT68216 Binding of NF1 40 0.48 51.24 4.59
22 INT19965 Positive_regulation of COL1A1 23 0.45 14.49 4.38
23 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32
24 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23
25 INT156137 Gene_expression of Col1a2 28 0.73 13.3 3.99
26 INT124815 Binding of Col2a1 9 0.37 10.27 3.93
27 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47
28 INT49238 Protein_catabolism of COL1A2 30 0.97 15.64 3.45
29 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35
30 INT81229 Binding of COL1A1 24 0.35 12.07 3.3
31 INT36032 Gene_expression of Col3a1 23 0.72 10.55 3.18
32 INT39867 Binding of Col2a1 9 0.35 7.65 3.18
33 INT154233 Negative_regulation of Lox 32 0.56 38.89 3.17
34 INT54832 Negative_regulation of Gene_expression of Col2a1 6 0.50 2.53 3.16
35 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
36 INT67719 Positive_regulation of Col1a1 21 0.44 8.87 3.12
37 INT171884 Positive_regulation of Gene_expression of Col2a1 11 0.23 8.04 3.02
38 INT14448 Localization of COL5A2 34 0.67 17.35 2.85
39 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66
40 INT96693 Binding of COL2A1 45 0.46 37.11 2.61
41 INT68091 Localization of COL1A1 19 0.66 9.13 2.56
42 INT173592 Binding of COL5A2 32 0.33 9.14 2.48
43 INT8890 Transcription of Col1a1 10 0.63 4.02 2.48
44 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45
45 INT61434 Regulation of Nf1 3 0.26 1.39 2.4
46 INT124862 Gene_expression of Col5a1 4 0.17 2.05 2.32
47 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3
48 INT64700 Binding of Nf1 14 0.45 15.24 2.29
49 INT94002 Regulation of Lox 13 0.38 8.41 2.29
50 INT64777 Negative_regulation of COL5A2 32 0.38 17.4 2.28
51 INT61684 Localization of COL1A2 20 0.73 9.31 2.26
52 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23
53 INT126513 Gene_expression of Col1a1 23 0.75 10.92 2.18
54 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17
55 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12
56 INT144364 Negative_regulation of Lmx1b 5 0.45 3.35 2.12
57 INT117457 Positive_regulation of Gene_expression of Lox 9 0.39 6.97 2.08
58 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06
59 INT113717 Negative_regulation of Gene_expression of COL1A1 21 0.41 6.14 2.01
60 INT120857 Localization of Col1a1 10 0.71 2.33 1.93
61 INT84510 Positive_regulation of Nf1 8 0.69 9.52 1.93
62 INT94001 Positive_regulation of Lox 15 0.60 7.46 1.92
63 INT69181 Positive_regulation of Col3a1 10 0.33 5.54 1.91
64 INT152155 Positive_regulation of Col1a2 7 0.56 10.18 1.89
65 INT68181 Binding of Nf1 6 0.48 8.14 1.88
66 INT96116 Transcription of COL1A1 10 0.44 4.57 1.81
67 INT164407 Negative_regulation of Gene_expression of Col2a1 6 0.39 4 1.78
68 INT84375 Regulation of COL1A2 6 0.44 8.75 1.72
69 INT14405 Gene_expression of SERPINF2 14 0.65 3 1.64
70 INT220992 Protein_catabolism of Col2a1 8 0.40 5.55 1.64
71 INT139317 Negative_regulation of Col1a2 8 0.41 7.17 1.54
72 INT164410 Negative_regulation of Col2a1 4 0.39 3.75 1.53
73 INT153201 Negative_regulation of Gene_expression of Col1a1 7 0.38 6.37 1.52
74 INT14404 Negative_regulation of SERPINF2 11 0.47 3.15 1.47
75 INT142719 Binding of Col1a1 7 0.34 5.83 1.47
76 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43
77 INT62669 Positive_regulation of COL1A2 13 0.49 6.89 1.4
78 INT71847 Positive_regulation of Positive_regulation of Col3a1 2 0.33 0.61 1.39
79 INT22558 Gene_expression of COL3A1 10 0.78 7.22 1.36
80 INT120860 Positive_regulation of Gene_expression of Col1a1 12 0.44 4.84 1.34
81 INT54831 Regulation of Gene_expression of Col2a1 4 0.39 2.3 1.31
82 INT353966 Negative_regulation of Gene_expression of Lmx1b 1 0.43 0.16 1.31
83 INT117232 Localization of COL2A1 11 0.72 7.34 1.3
84 INT133255 Gene_expression of Anxa2 8 0.41 8.52 1.3
85 INT112650 Positive_regulation of Col1a1 3 0.30 5.96 1.3
86 INT172872 Positive_regulation of Lox 12 0.49 12.99 1.29
87 INT221801 Localization of Lox 2 0.24 0.99 1.28
88 INT124861 Positive_regulation of Col5a1 2 0.09 0.75 1.27
89 INT131645 Negative_regulation of Nf1 10 0.58 8.12 1.24
90 INT128714 Transcription of Col2a1 6 0.52 2.13 1.24
91 INT59473 Negative_regulation of Col1a1 4 0.25 1.33 1.24
92 INT61993 Gene_expression of NF1 29 0.78 34.47 1.23
93 INT71845 Positive_regulation of Positive_regulation of Col1a1 1 0.34 0.15 1.23
94 INT140033 Positive_regulation of Gene_expression of Col1a1 6 0.14 3.68 1.2
95 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
96 INT176463 Protein_catabolism of Col2a1 4 0.35 1.94 1.2
97 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
98 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
99 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11
100 INT101104 Positive_regulation of Gene_expression of COL1A2 12 0.69 5.87 1.09
101 INT5643 Positive_regulation of SERPINF2 3 0.35 0.94 1.09
102 INT54835 Regulation of Col2a1 5 0.59 2.08 1.07
103 INT156427 Localization of FOXC1 2 0.73 1.36 1.07
104 INT182285 Positive_regulation of Positive_regulation of COL5A2 2 0.13 0.37 1.07
105 INT263822 Positive_regulation of Gene_expression of LOX 8 0.50 11 1.06
106 INT84235 Positive_regulation of Col11a1 2 0.01 0.09 1.03
107 INT133102 Negative_regulation of Gene_expression of COL1A2 8 0.08 2.56 1.02
108 INT101841 Localization of SERPINF2 4 0.68 1.27 1.01
109 INT214609 Positive_regulation of Gene_expression of FOXC1 1 0.08 1.78 1
110 INT156614 Regulation of Gene_expression of COL1A1 6 0.33 2.51 0.99
111 INT168233 Positive_regulation of Transcription of Col2a1 2 0.45 1.78 0.99
112 INT46334 Binding of FOXC1 2 0.36 2.66 0.99
113 INT43131 Regulation of FOXC1 3 0.36 1.09 0.98
114 INT81878 Gene_expression of TGFB2 3 0.42 2.02 0.97
115 INT129997 Protein_catabolism of Col1a1 5 0.96 3.43 0.96
116 INT13696 Regulation of COL3A1 2 0.45 2.97 0.95
117 INT155867 Transcription of COL1A2 8 0.69 2.9 0.94
118 INT204547 Positive_regulation of Gene_expression of Col1a2 2 0.04 2.08 0.91
119 INT172868 Regulation of Lox 5 0.43 5.76 0.9
120 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
121 INT8888 Regulation of Col1a1 4 0.13 1.97 0.86
122 INT263817 Regulation of Negative_regulation of LOX 1 0.33 2.36 0.86
123 INT73030 Regulation of SERPINF2 10 0.39 5.69 0.8
124 INT192156 Negative_regulation of Col1a1 6 0.39 3.92 0.8
125 INT93737 Gene_expression of Tgfb2 2 0.03 1.16 0.77
126 INT93736 Positive_regulation of Gene_expression of Tgfb2 2 0.02 1.16 0.77
127 INT173506 Positive_regulation of Col2a1 4 0.20 3.42 0.76
128 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
129 INT116379 Protein_catabolism of Lox 2 0.77 0.64 0.72
130 INT91384 Positive_regulation of Localization of COL1A2 3 0.49 1.42 0.71
131 INT169421 Positive_regulation of FOXC1 4 0.49 2.42 0.7
132 INT37617 Regulation of Gene_expression of Col2a1 3 0.31 1.48 0.7
133 INT156138 Negative_regulation of Gene_expression of Col1a2 2 0.55 2.07 0.7
134 INT73977 Gene_expression of Serpinh1 14 0.54 8.14 0.69
135 INT68179 Gene_expression of Nf1 9 0.78 8.87 0.68
136 INT104305 Binding of COL3A1 2 0.35 3.45 0.68
137 INT179133 Localization of Nf1 2 0.80 2.18 0.68
138 INT65259 Positive_regulation of Gene_expression of Lox 7 0.66 2.8 0.67
139 INT49650 Gene_expression of Nf1 4 0.76 3.38 0.67
140 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66
141 INT125709 Positive_regulation of Gene_expression of Col3a1 7 0.27 5.17 0.65
142 INT115297 Positive_regulation of TGFB2 4 0.29 1.91 0.65
143 INT192321 Regulation of LOX 2 0.33 2.72 0.65
144 INT22556 Positive_regulation of Gene_expression of COL3A1 5 0.37 4.25 0.64
145 INT11890 Protein_catabolism of COL3A1 2 0.77 2.41 0.64
146 INT124858 Negative_regulation of Positive_regulation of Col5a1 1 0.01 0.75 0.64
147 INT3503 Localization of COL11A1 3 0.65 2.17 0.63
148 INT101177 Regulation of COL5A2 12 0.45 4.03 0.62
149 INT63389 Localization of Col2a1 7 0.68 1.95 0.6
150 INT174540 Positive_regulation of Localization of COL5A2 2 0.04 2.44 0.6
151 INT267114 Positive_regulation of Lmx1b 2 0.50 0.96 0.6
152 INT151670 Negative_regulation of Protein_catabolism of Lox 1 0.37 0.41 0.6
153 INT180967 Negative_regulation of Protein_catabolism of COL5A2 4 0.05 1.45 0.59
154 INT142625 Negative_regulation of Localization of SERPINF2 1 0.31 0.16 0.59
155 INT115292 Regulation of TGFB2 4 0.17 2.79 0.58
156 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
157 INT263823 Negative_regulation of Gene_expression of LOX 1 0.31 2.49 0.57
158 INT138429 Negative_regulation of Gene_expression of Col3a1 3 0.17 2.51 0.54
159 INT180966 Positive_regulation of Protein_catabolism of COL5A2 7 0.06 4.55 0.53
160 INT130047 Localization of TGFB2 3 0.16 3.65 0.53
161 INT242093 Negative_regulation of Positive_regulation of COL5A2 1 0.08 0 0.53
162 INT68092 Negative_regulation of Localization of COL1A1 1 0.48 0 0.53
163 INT129999 Protein_catabolism of Col1a2 3 0.96 1.21 0.52
164 INT61992 Positive_regulation of Gene_expression of NF1 3 0.50 4.47 0.51
165 INT71274 Gene_expression of Acan 3 0.12 0.99 0.5
166 INT8886 Regulation of Transcription of Col1a1 1 0.04 0 0.5
167 INT32183 Positive_regulation of Negative_regulation of Col2a1 2 0.46 1.01 0.49
168 INT316933 Transcription of Nf1 1 0.18 0.49 0.47
169 INT316939 Positive_regulation of Transcription of Nf1 1 0.16 0.49 0.47
170 INT172866 Regulation of Gene_expression of Lox 5 0.19 4.81 0.46
171 INT92684 Positive_regulation of Col3a1 5 0.56 1.79 0.45
172 INT125840 Positive_regulation of Binding of Col2a1 1 0.43 1.21 0.45
173 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44
174 INT267113 Regulation of Gene_expression of Lmx1b 2 0.62 1.36 0.44
175 INT125708 Negative_regulation of Col3a1 2 0.16 1.37 0.42
176 INT173582 Negative_regulation of Localization of COL5A2 6 0.05 3.24 0.41
177 INT236948 Positive_regulation of Gene_expression of Col5a1 1 0.10 1.15 0.41
178 INT320812 Positive_regulation of Localization of COL1A1 1 0.05 1.04 0.4
179 INT248931 Positive_regulation of Tgfb2 1 0.03 0 0.4
180 INT3504 Binding of COL11A1 1 0.32 0 0.4
181 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
182 INT147700 Positive_regulation of Gene_expression of Col11a1 1 0.01 0 0.39
183 INT63550 Positive_regulation of Protein_catabolism of COL1A2 4 0.25 3.22 0.38
184 INT257288 Regulation of Gene_expression of COL5A2 7 0.21 2.52 0.36
185 INT294604 Binding of Serpinh1 5 0.16 4.02 0.36
186 INT97828 Positive_regulation of Positive_regulation of Lox 2 0.43 1.22 0.35
187 INT257319 Negative_regulation of Gene_expression of Lox 2 0.04 1.62 0.35
188 INT123421 Binding of Lmx1b 1 0.36 0.54 0.35
189 INT203309 Regulation of Anxa2 1 0.42 1.03 0.35
190 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
191 INT112334 Regulation of NF1 18 0.52 15.85 0.34
192 INT130739 Binding of Col1a2 2 0.35 2.38 0.34
193 INT155865 Positive_regulation of Transcription of COL1A2 2 0.46 0.6 0.34
194 INT163709 Regulation of Negative_regulation of COL1A1 1 0.29 0.93 0.34
195 INT209302 Gene_expression of Scx 1 0.20 0.05 0.33
196 INT54833 Positive_regulation of Col2a1 5 0.52 1.1 0.32
197 INT65208 Positive_regulation of Positive_regulation of COL1A2 3 0.14 2.63 0.32
198 INT131134 Regulation of Col5a1 1 0.06 0 0.32
199 INT128754 Binding of Foxc1 1 0.01 0.43 0.32
200 INT180577 Positive_regulation of Protein_catabolism of COL2A1 2 0.12 0.91 0.31
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