GO:0030229

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Name very-low-density lipoprotein particle receptor activity
Categary Function
Go Slim No
Go Link GO:0030229
Unique Molecular Interactions 99
Total Molecular Interactions 130
Total Single Events 1231
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for very-low-density lipoprotein particle receptor activity. They are ordered first by their pain relevance and then by number of times they were reported for very-low-density lipoprotein particle receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT144551 Binding of Lrp8 and Sepp1 1 0.55 1.73 0.93
2 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67
3 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
4 INT198931 Binding of Dlg4 and Lrp8 1 0.06 0.23 0.46
5 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
6 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
7 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
8 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
9 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
10 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
11 INT149791 Binding of Lrp8 and Reln 4 0.36 0.38 0.22
12 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
13 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
14 INT21620 Binding of Ttpa and Vldlr 1 0.22 0.27 0.12
15 INT149792 Binding of Reln and Vldlr 3 0.51 0.35 0.11
16 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
17 INT99140 LDLR Positive_regulation of Localization of VCAM1 1 0.05 0.44 0.11
18 INT341018 Lrp8 Positive_regulation of Phosphorylation of DAB1 1 0.02 0.2 0.09
19 INT71344 Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
20 INT66590 Gnrhr Regulation of Ldlr 1 0.02 0.4 0.06
21 INT71343 Negative_regulation of Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
22 INT341019 Binding of VLDLR and Reln 1 0.01 0.1 0.05
23 INT340925 VLDLR Positive_regulation of Phosphorylation of DAB1 1 0.01 0.1 0.05
24 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05
25 INT288853 Binding of HSD11B1 and LDLR 1 0.26 1.52 0.04
26 INT198923 Gene_expression of Lrp8 Positive_regulation of Gene_expression of Lifr 1 0.01 0 0.04
27 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04
28 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
29 INT198922 Lrp8 Negative_regulation of Binding of Vldlr 1 0.19 0 0.04
30 INT149794 Binding of LRP8 and Vldlr 1 0.02 0.17 0.04
31 INT198917 Lrp8 Negative_regulation of Binding of Reln 1 0.15 0 0.04
32 INT294217 Binding of PLG and Ldlr 1 0.33 0.06 0.04
33 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04
34 INT198930 Binding of Lrp8 and Vldlr 1 0.16 0 0.04
35 INT294210 Binding of Ldlr and Plat 1 0.42 0.06 0.04
36 INT149793 Binding of LRP8 and Reln 1 0.03 0.17 0.04
37 INT294206 Ldlr Positive_regulation of Grin1 1 0.26 0 0.03
38 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
39 INT239351 Binding of CETP and Ldlr 1 0.15 1.01 0.03
40 INT251961 Binding of LDLR and SNRNP70 2 0.04 0.55 0
41 INT341003 Reln Positive_regulation of Positive_regulation of Lrp8 1 0.03 0.11 0
42 INT209984 Binding of LDLR and LRP1 1 0.08 0 0
43 INT198920 Binding of Ldlr and Lrpap1 1 0.05 0.06 0
44 INT341015 VLDLR Positive_regulation of Lrp8 1 0.02 0.06 0
45 INT209987 Binding of APOE and LDLR 1 0.24 0 0
46 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0
47 INT340929 VLDLR Positive_regulation of PIK3CB 1 0.01 0.06 0
48 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0
49 INT198918 Binding of Gpx3 and Lrp8 1 0.00 0.17 0
50 INT211576 Vldlr Positive_regulation of Lpl 1 0.38 0.24 0
51 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
52 INT317842 Hdlcl1 Positive_regulation of Ldlr 1 0.00 1.11 0
53 INT302596 Eef1a2 Negative_regulation of LDLR 1 0.14 0.31 0
54 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
55 INT341017 Binding of VLDLR and Lrp8 1 0.02 0 0
56 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0
57 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
58 INT211577 Vldlr Regulation of Gene_expression of Lpin1 1 0.27 0.12 0
59 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0
60 INT339699 LDLR Positive_regulation of SREBF2 1 0.08 1.08 0
61 INT198915 Binding of App and Lrp8 1 0.24 0.17 0
62 INT340923 VLDLR Positive_regulation of DAB1 1 0.01 0.06 0
63 INT198925 Binding of App and Ldlr 1 0.14 0.15 0
64 INT339694 LDLR Positive_regulation of Gene_expression of SREBF2 1 0.08 1.08 0
65 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
66 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
67 INT251964 Binding of LDLR and RS1 1 0.00 0.31 0
68 INT341024 VLDLR Positive_regulation of Reln 1 0.02 0 0
69 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0
70 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0
71 INT312630 Agrn Positive_regulation of Ldlr 1 0.14 0.66 0
72 INT198928 Binding of Apbb1 and Lrp8 1 0.07 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for very-low-density lipoprotein particle receptor activity. They are ordered first by their pain relevance and then by number of times they were reported in very-low-density lipoprotein particle receptor activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
2 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
3 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
4 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
5 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
6 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
7 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
8 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
9 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
10 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
11 INT23199 Binding of LDLR 22 0.47 17.08 1.16
12 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
13 INT198879 Localization of Vldlr 6 0.39 0.58 1.1
14 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
15 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97
16 INT144548 Gene_expression of Lrp8 8 0.67 0.57 0.96
17 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
18 INT198912 Localization of Lrp8 1 0.54 0.17 0.85
19 INT95561 Negative_regulation of Vldlr 9 0.53 2.59 0.84
20 INT198899 Regulation of Localization of Vldlr 1 0.24 0.17 0.67
21 INT198905 Regulation of Localization of Lrp8 1 0.33 0.17 0.66
22 INT142802 Binding of Ldlr 8 0.47 5.08 0.65
23 INT144550 Binding of Lrp8 4 0.48 1.58 0.62
24 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6
25 INT200090 Positive_regulation of Gene_expression of Ldlr 5 0.37 3.67 0.59
26 INT8638 Regulation of Vldlr 3 0.44 1.57 0.51
27 INT10862 Positive_regulation of Vldlr 4 0.15 2.96 0.49
28 INT198884 Gene_expression of Vldlr 13 0.70 2.41 0.44
29 INT197012 Regulation of Gene_expression of LDLR 4 0.40 1.31 0.4
30 INT138380 Regulation of Transcription of Ldlr 1 0.38 0.21 0.38
31 INT138379 Transcription of Ldlr 1 0.59 0.21 0.38
32 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37
33 INT5168 Regulation of Binding of Ldlr 1 0.45 0 0.36
34 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34
35 INT159311 Gene_expression of Vldlr 2 0.65 0.89 0.34
36 INT335105 Localization of VLDLR 1 0.21 0.71 0.33
37 INT10861 Negative_regulation of Vldlr 5 0.11 3.22 0.27
38 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24
39 INT37790 Localization of Ldlr 5 0.38 2.29 0.23
40 INT268222 Negative_regulation of Localization of Vldlr 1 0.02 0.26 0.23
41 INT75874 Positive_regulation of Regulation of Vldlr 1 0.11 0.42 0.2
42 INT252222 Regulation of Ldlr 5 0.34 4.3 0.19
43 INT5165 Positive_regulation of Binding of Ldlr 1 0.50 0 0.19
44 INT212383 Gene_expression of VLDLR 4 0.28 1.19 0.18
45 INT198874 Binding of Vldlr 3 0.32 0.73 0.18
46 INT5167 Negative_regulation of Binding of Ldlr 1 0.43 0 0.17
47 INT17474 Negative_regulation of Positive_regulation of LDLR 4 0.37 2.93 0.16
48 INT209992 Negative_regulation of Transcription of LDLR 2 0.29 0 0.16
49 INT87515 Negative_regulation of Gene_expression of LDLR 2 0.09 1.96 0.16
50 INT198868 Regulation of Vldlr 1 0.14 0.73 0.16
51 INT198890 Regulation of Lrp8 1 0.20 0.74 0.16
52 INT211532 Localization of Ldlr 4 0.56 3.52 0.13
53 INT335121 Positive_regulation of Gene_expression of VLDLR 1 0.15 0.35 0.13
54 INT198900 Positive_regulation of Vldlr 3 0.26 1.44 0.12
55 INT198913 Positive_regulation of Lrp8 2 0.36 0.17 0.12
56 INT215136 Regulation of Gene_expression of Ldlr 2 0.12 0.76 0.12
57 INT215137 Regulation of Gene_expression of Vldlr 1 0.04 0.55 0.12
58 INT116739 Protein_catabolism of Ldlr 1 0.87 1.18 0.12
59 INT17084 Binding of Vldlr 1 0.29 0.42 0.11
60 INT34582 Negative_regulation of Positive_regulation of Ldlr 2 0.03 1.33 0.1
61 INT175218 Positive_regulation of LRP8 1 0.05 1.55 0.1
62 INT198891 Regulation of Protein_catabolism of Lrp8 1 0.20 0 0.09
63 INT198911 Protein_catabolism of Lrp8 1 0.47 0 0.09
64 INT198876 Protein_catabolism of Vldlr 1 0.34 0 0.09
65 INT167019 Negative_regulation of Gene_expression of Ldlr 3 0.42 0.76 0.08
66 INT57557 Negative_regulation of VLDLR 2 0.19 1.23 0.08
67 INT293307 Regulation of Gene_expression of Ldlr 3 0.19 2.77 0.07
68 INT198869 Negative_regulation of Lrp8 2 0.31 0.05 0.05
69 INT340996 Phosphorylation of VLDLR 1 0.14 0.1 0.05
70 INT348079 Negative_regulation of Negative_regulation of Ldlr 1 0.12 1.03 0.05
71 INT340979 Phosphorylation of Lrp8 1 0.21 0.1 0.05
72 INT211531 Negative_regulation of Gene_expression of Vldlr 1 0.38 0.21 0.04
73 INT198901 Positive_regulation of Gene_expression of Lrp8 1 0.32 0 0.04
74 INT246581 Negative_regulation of Gene_expression of VLDLR 1 0.11 0.22 0.04
75 INT197014 Localization of LDLR 8 0.63 3.29 0.03
76 INT297432 Positive_regulation of Localization of Ldlr 2 0.14 0.35 0.03
77 INT176889 Negative_regulation of Binding of LDLR 2 0.41 1.2 0
78 INT276260 Negative_regulation of Localization of LDLR 2 0.40 1.34 0
79 INT353783 Positive_regulation of Gene_expression of Vldlr 1 0.28 0.51 0
80 INT340942 Positive_regulation of Positive_regulation of Lrp8 1 0.13 0 0
81 INT39405 Regulation of Binding of LDLR 1 0.17 0 0
82 INT353784 Protein_catabolism of Ldlr 1 0.52 1.85 0
83 INT332947 Positive_regulation of Negative_regulation of Ldlr 1 0.37 1.54 0
84 INT336099 Transcription of Ldlr 1 0.25 0.36 0
85 INT274378 Binding of LRP8 1 0.04 0.52 0
86 INT336103 Positive_regulation of Transcription of Ldlr 1 0.22 0.47 0
87 INT340983 Positive_regulation of Positive_regulation of VLDLR 1 0.08 0.14 0
88 INT340997 Negative_regulation of Binding of VLDLR 1 0.07 0 0
89 INT340994 Binding of VLDLR 1 0.06 0 0
90 INT170750 Negative_regulation of Negative_regulation of LDLR 1 0.07 0.93 0
91 INT340987 Negative_regulation of Positive_regulation of VLDLR 1 0.07 0.08 0
92 INT340991 Positive_regulation of VLDLR 1 0.08 0.2 0
93 INT268450 Protein_catabolism of LDLR 1 0.07 0.14 0
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