GO:0030247

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Name polysaccharide binding
Categary Function
Go Slim No
Go Link GO:0030247
Unique Molecular Interactions 72
Total Molecular Interactions 104
Total Single Events 673
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for polysaccharide binding. They are ordered first by their pain relevance and then by number of times they were reported for polysaccharide binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
2 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
3 INT231392 Enpp2 Positive_regulation of Gene_expression of Lpar1 2 0.38 2.19 0.93
4 INT239064 Binding of Mbl1 and IgG 1 0.03 2.59 0.78
5 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
6 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76
7 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
8 INT167583 ENPP2 Positive_regulation of Gene_expression of LPA 1 0.08 0.93 0.51
9 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
10 INT225775 Enpp1 Positive_regulation of Ppi-rs 1 0.06 2.49 0.44
11 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
12 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
13 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
14 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
15 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
16 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
17 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37
18 INT225776 Enpp1 Positive_regulation of Positive_regulation of Ppi-rs 1 0.08 1.67 0.28
19 INT225784 Il1 Negative_regulation of Gene_expression of Enpp1 1 0.08 0.99 0.28
20 INT167582 ENPP2 Regulation of Gene_expression of LPA 1 0.05 0.61 0.26
21 INT296464 Binding of Cacng2 and Tinagl1 1 0.06 0.25 0.23
22 INT296449 Binding of Gria1 and Tinagl1 1 0.08 0.25 0.23
23 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
24 INT51345 Binding of Vtn and Pomc 1 0.03 0 0.2
25 INT158613 Binding of Serpine1 and Vtn 1 0.02 0.95 0.16
26 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
27 INT118257 Binding of ENPP1 and SUGT1 1 0.00 0.87 0.16
28 INT276958 Binding of Tlr2 and Clec7a 1 0.09 0.58 0.15
29 INT106009 Binding of VTN and Plaur 1 0.05 1.37 0.15
30 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
31 INT174892 Binding of ADRB3 and ENPP3 1 0.04 0.4 0.14
32 INT300512 Binding of Plau and Vtn 1 0.06 2.28 0.13
33 INT300511 Binding of Plaur and Vtn 1 0.10 2.28 0.13
34 INT225783 Enpp1 Regulation of Ppi-rs 1 0.07 0.68 0.13
35 INT301414 Binding of Enpp2 and Twist1 1 0.08 1.26 0.13
36 INT167757 Binding of Enpp2 and Dmbx1 1 0.22 0.33 0.13
37 INT300513 Binding of Serpine1 and Vtn 1 0.17 2.27 0.13
38 INT238036 Binding of ENPP1 and OPLL 1 0.27 0.66 0.12
39 INT225785 Enpp3 Regulation of Ppi-rs 1 0.00 0.69 0.11
40 INT158612 Binding of Vtn and Plaur 1 0.00 0.43 0.1
41 INT51346 Binding of Vtn and Diablo 1 0.02 0 0.1
42 INT51342 Binding of Pomc and Vtn 1 0.23 0 0.1
43 INT51344 Binding of Clu and Vtn 1 0.06 0 0.1
44 INT158614 Negative_regulation of Binding of Serpine1 and Vtn 1 0.03 0.48 0.09
45 INT225805 Binding of SNRNP70 and Enpp1 1 0.42 1.43 0.09
46 INT301402 Enpp2 Positive_regulation of Lpar1 2 0.33 0.55 0.07
47 INT301411 Enpp2 Positive_regulation of Csf2 1 0.04 0.59 0.07
48 INT301403 Enpp2 Positive_regulation of Tnfrsf11a 1 0.05 0.59 0.07
49 INT332017 Binding of Ighm and Mbl1 1 0.11 0.26 0.06
50 INT225790 Il1 Regulation of Gene_expression of Enpp1 1 0.07 0.43 0.05
51 INT225786 Enpp3 Positive_regulation of Ppi-rs 1 0.00 0.32 0.05
52 INT225808 SNRNP70 Regulation of Enpp1 1 0.30 0.71 0.04
53 INT247768 Fcer2a Positive_regulation of Enpp1 1 0.00 0.29 0.04
54 INT225801 Binding of Enpp1 and Npp 1 0.17 0.46 0.04
55 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04
56 INT301413 Positive_regulation of Binding of Enpp2 and Twist1 1 0.11 0.18 0.03
57 INT225802 Binding of Enpp1 and Ppi-rs 1 0.04 1 0.03
58 INT301408 Positive_regulation of Binding of Enpp1 and Twist1 1 0.06 0.18 0.03
59 INT301406 Binding of Enpp1 and Twist1 1 0.04 0.18 0.03
60 INT321958 Binding of Vtn and Ceacam1 1 0.02 0.27 0
61 INT345149 Enpp2 Regulation of Gene_expression of Lpar1 1 0.01 0.41 0
62 INT262915 ENPP2 Regulation of SMG1 1 0.22 0.07 0
63 INT262913 ENPP2 Regulation of PCSK7 1 0.02 0.07 0
64 INT291108 AGL Regulation of Gene_expression of PDK4 1 0.01 0 0
65 INT225807 Enpp2 Positive_regulation of ALPI 1 0.00 0.23 0
66 INT345153 Dmbx1 Regulation of Enpp2 1 0.00 0.41 0
67 INT301401 Binding of Enpp1 and Enpp2 1 0.23 0.54 0
68 INT225782 Tnfrsf11b Regulation of Enpp1 1 0.12 0.74 0
69 INT346744 Binding of Dlg4 and Tinagl1 1 0.03 0 0
70 INT225792 Gene_expression of Enpp2 Positive_regulation of Ppi-rs 1 0.01 0.21 0
71 INT213025 Vtn Positive_regulation of Apc 1 0.01 1.19 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for polysaccharide binding. They are ordered first by their pain relevance and then by number of times they were reported in polysaccharide binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
2 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
3 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
4 INT167755 Gene_expression of Enpp2 12 0.77 57.31 5.3
5 INT239050 Negative_regulation of Mbl1 1 0.45 15 4.24
6 INT2936 Gene_expression of AGL 36 0.49 9.55 3.63
7 INT68445 Gene_expression of ENPP1 10 0.70 10.8 3.3
8 INT146693 Gene_expression of Mbl1 17 0.59 10.99 3.13
9 INT24821 Binding of VTN 14 0.47 5.83 3
10 INT207851 Regulation of Enpp1 5 0.45 4.42 2.96
11 INT167585 Negative_regulation of ENPP2 7 0.36 5.19 2.74
12 INT107597 Binding of Enpp1 5 0.37 3.35 2.23
13 INT35745 Negative_regulation of AGL 29 0.50 9.16 2.03
14 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97
15 INT316778 Positive_regulation of Gene_expression of ENPP1 1 0.62 7.2 1.97
16 INT10976 Negative_regulation of ENPP3 13 0.42 5.11 1.92
17 INT224529 Positive_regulation of Gene_expression of Enpp1 15 0.70 12.75 1.81
18 INT63029 Gene_expression of Vtn 4 0.14 2.8 1.8
19 INT105325 Gene_expression of ENPP2 5 0.75 1.32 1.72
20 INT332460 Regulation of Binding of Enpp1 1 0.05 0.78 1.5
21 INT10975 Gene_expression of ENPP3 16 0.76 3.28 1.36
22 INT239060 Binding of Mbl1 5 0.32 4.89 1.27
23 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24
24 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23
25 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16
26 INT216372 Localization of ENPP3 1 0.13 2.97 0.99
27 INT273038 Regulation of Vtn 3 0.08 2.26 0.91
28 INT41873 Positive_regulation of Mbl1 4 0.39 2.1 0.9
29 INT99477 Negative_regulation of Enpp3 3 0.30 2.45 0.88
30 INT225769 Positive_regulation of Gene_expression of Enpp2 3 0.69 16.67 0.74
31 INT216384 Positive_regulation of ENPP3 3 0.54 0.84 0.69
32 INT35098 Localization of Enpp1 4 0.75 0.81 0.67
33 INT51336 Binding of Vtn 3 0.12 1.5 0.66
34 INT5262 Positive_regulation of AGL 14 0.40 7.51 0.65
35 INT76902 Binding of AGL 3 0.02 2.23 0.64
36 INT34723 Regulation of Mbl1 2 0.41 2.26 0.63
37 INT346193 Positive_regulation of Gene_expression of VTN 1 0.25 1.54 0.63
38 INT5261 Localization of AGL 10 0.36 3.17 0.61
39 INT160705 Positive_regulation of Enpp3 2 0.20 1.26 0.56
40 INT23118 Positive_regulation of Gene_expression of AGL 4 0.30 1.74 0.54
41 INT63028 Positive_regulation of Gene_expression of Vtn 1 0.03 1.01 0.53
42 INT225772 Regulation of Gene_expression of Enpp1 1 0.62 1.6 0.4
43 INT160707 Regulation of Positive_regulation of Enpp3 1 0.13 0.19 0.38
44 INT225768 Positive_regulation of Enpp2 7 0.69 8.11 0.37
45 INT174895 Binding of ENPP3 2 0.06 0.74 0.37
46 INT47175 Negative_regulation of Negative_regulation of AGL 4 0.24 1.19 0.36
47 INT51340 Binding of Vtn 2 0.22 1.38 0.36
48 INT145457 Positive_regulation of Clec7a 2 0.04 0.17 0.34
49 INT216382 Transcription of ENPP3 1 0.11 0.43 0.3
50 INT109156 Negative_regulation of ENPP1 2 0.34 1.34 0.29
51 INT239056 Transcription of Mbl1 1 0.46 0.94 0.29
52 INT35283 Negative_regulation of Vtn 2 0.21 0.34 0.27
53 INT167586 Regulation of ENPP2 2 0.20 0.59 0.25
54 INT262928 Localization of ENPP2 1 0.58 1.11 0.24
55 INT2935 Negative_regulation of Gene_expression of AGL 4 0.24 2.07 0.23
56 INT335482 Regulation of Gene_expression of ENPP3 1 0.48 0 0.23
57 INT239058 Negative_regulation of Negative_regulation of Mbl1 1 0.29 0.57 0.22
58 INT123656 Positive_regulation of Localization of AGL 1 0.00 0.26 0.22
59 INT24818 Positive_regulation of Binding of VTN 1 0.49 0 0.18
60 INT216375 Negative_regulation of Localization of ENPP3 1 0.07 0.55 0.18
61 INT335483 Regulation of ENPP3 1 0.35 0 0.17
62 INT273031 Transcription of Vtn 1 0.12 0.81 0.17
63 INT339625 Binding of Clec7a 1 0.03 0.14 0.17
64 INT153911 Localization of Enpp2 4 0.75 2.6 0.16
65 INT175900 Regulation of ENPP1 1 0.00 1.96 0.16
66 INT252419 Phosphorylation of Enpp1 1 0.08 0.21 0.16
67 INT16940 Protein_catabolism of AGL 4 0.39 2.94 0.14
68 INT225771 Negative_regulation of Gene_expression of Enpp1 4 0.43 3.68 0.13
69 INT174896 Protein_catabolism of ENPP3 1 0.07 0.39 0.13
70 INT282445 Negative_regulation of Binding of Vtn 1 0.15 0.63 0.11
71 INT321952 Protein_catabolism of Vtn 1 0.11 0.68 0.1
72 INT107777 Phosphorylation of AGL 3 0.54 2.45 0.09
73 INT107776 Negative_regulation of Phosphorylation of AGL 1 0.37 0.99 0.09
74 INT64708 Negative_regulation of Gene_expression of VTN 1 0.37 0.44 0.09
75 INT67258 Positive_regulation of Positive_regulation of AGL 1 0.00 1 0.08
76 INT158611 Negative_regulation of Binding of Vtn 1 0.04 0.48 0.08
77 INT153679 Regulation of AGL 4 0.04 1.49 0.07
78 INT153908 Negative_regulation of Enpp2 2 0.42 1.4 0.07
79 INT301393 Positive_regulation of Positive_regulation of Enpp2 1 0.50 0.49 0.07
80 INT301398 Positive_regulation of Binding of Enpp2 1 0.50 0.49 0.07
81 INT301392 Negative_regulation of Gene_expression of Enpp2 1 0.58 3.16 0.07
82 INT276937 Localization of Clec7a 1 0.14 0.23 0.07
83 INT301396 Binding of Enpp2 1 0.37 0.49 0.07
84 INT189231 Binding of ENPP1 1 0.07 0.56 0.06
85 INT277163 Gene_expression of Vtn 1 0.02 1.05 0.04
86 INT301400 Negative_regulation of Negative_regulation of Enpp2 1 0.42 0.9 0.04
87 INT301387 Regulation of Gene_expression of Enpp2 1 0.61 9.41 0.04
88 INT153910 Regulation of Enpp2 2 0.45 2.1 0.03
89 INT10977 Negative_regulation of Gene_expression of ENPP3 2 0.34 0.13 0.03
90 INT301386 Positive_regulation of Localization of Enpp2 1 0.44 0.77 0.03
91 INT319969 Positive_regulation of Negative_regulation of Enpp1 1 0.06 0.77 0.03
92 INT129802 Gene_expression of Clec7a 5 0.13 0.51 0
93 INT303847 Positive_regulation of Negative_regulation of AGL 3 0.17 0.61 0
94 INT125075 Gene_expression of Enpp3 2 0.19 0.35 0
95 INT346729 Localization of Tinagl1 1 0.73 0 0
96 INT160706 Positive_regulation of Gene_expression of Enpp3 1 0.14 0 0
97 INT201215 Negative_regulation of Binding of VTN 1 0.19 0.69 0
98 INT312967 Positive_regulation of Binding of AGL 1 0.03 0.55 0
99 INT175261 Positive_regulation of Negative_regulation of VTN 1 0.02 0.77 0
100 INT301390 Transcription of Enpp2 1 0.69 0 0
101 INT276944 Regulation of Clec7a 1 0.05 0 0
102 INT312966 Regulation of Gene_expression of AGL 1 0.03 0.27 0
103 INT262932 Positive_regulation of ENPP2 1 0.34 0.07 0
104 INT125073 Regulation of Enpp3 1 0.06 0.33 0
105 INT129801 Positive_regulation of Gene_expression of Clec7a 1 0.04 0.38 0
106 INT279581 Regulation of VTN 1 0.01 0.18 0
107 INT346732 Gene_expression of Tinagl1 1 0.65 0 0
108 INT125074 Localization of Enpp3 1 0.15 0.67 0
109 INT239057 Negative_regulation of Gene_expression of Mbl1 1 0.28 0.05 0
110 INT297264 Negative_regulation of Binding of AGL 1 0.01 1.2 0
111 INT262930 Negative_regulation of Gene_expression of ENPP2 1 0.35 0 0
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