GO:0030264

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Name nuclear fragmentation involved in apoptotic nuclear change
Categary Process
Go Slim No
Go Link GO:0030264
Unique Molecular Interactions 275
Total Molecular Interactions 329
Total Single Events 4782
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for nuclear fragmentation involved in apoptotic nuclear change. They are ordered first by their pain relevance and then by number of times they were reported for nuclear fragmentation involved in apoptotic nuclear change. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT155891 Nps Negative_regulation of Positive_regulation of Casp3 1 0.27 0.17 3.48
2 INT106750 Pes1 Negative_regulation of Positive_regulation of Casp3 3 0.23 0 2.35
3 INT85252 Negative_regulation of Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.26
4 INT85251 Chi3l1 Positive_regulation of Casp3 1 0.01 0 2.25
5 INT106753 Pes1 Negative_regulation of Gene_expression of Casp3 2 0.12 0 2.19
6 INT146587 Npff Negative_regulation of Positive_regulation of Casp3 1 0.05 0.18 1.92
7 INT146586 Npff Negative_regulation of Gene_expression of Casp3 1 0.06 0.18 1.92
8 INT106751 Pes1 Negative_regulation of Casp3 2 0.23 0 1.54
9 INT137657 Gorasp2 Regulation of Binding of Casp3 1 0.09 0 1.52
10 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
11 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
12 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
13 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
14 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
15 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
16 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
17 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
18 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
19 INT155890 Nps Negative_regulation of Gene_expression of Casp3 1 0.27 0.05 1.15
20 INT112607 DNAJC15 Negative_regulation of Positive_regulation of Casp3 1 0.03 0.14 1.12
21 INT159235 H2-M3 Negative_regulation of Casp3 1 0.05 0 1.12
22 INT159236 H2-M3 Positive_regulation of Casp3 1 0.06 0 1.12
23 INT155894 Nps Regulation of Gene_expression of Casp3 1 0.33 0.07 1.09
24 INT74460 GTS Negative_regulation of Casp3 1 0.04 0.37 1.08
25 INT159237 Gpm6a Positive_regulation of Casp3 1 0.03 0 1.07
26 INT307047 Foxm1 Positive_regulation of Casp3 1 0.11 0.06 1.03
27 INT98556 Oprm1 Positive_regulation of Casp3 1 0.38 0.36 1.01
28 INT98180 Aap Positive_regulation of Positive_regulation of Casp3 1 0.00 1.08 0.97
29 INT155893 Nps Regulation of Casp3 1 0.24 0.08 0.95
30 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92
31 INT148806 Diablo Positive_regulation of Positive_regulation of Casp3 1 0.03 1.02 0.89
32 INT147885 Negative_regulation of Slc6a3 Positive_regulation of Positive_regulation of Casp3 1 0.13 0 0.88
33 INT307045 Tmie Negative_regulation of Positive_regulation of Casp3 1 0.01 0.29 0.85
34 INT116250 Vta1 Positive_regulation of Casp3 1 0.01 0 0.82
35 INT56236 Casp3 Positive_regulation of Gene_expression of RT1-Cl 1 0.00 0.45 0.82
36 INT307044 Tmie Regulation of Casp3 1 0.01 0 0.75
37 INT114860 Negative_regulation of Insrr Positive_regulation of Casp3 1 0.02 0.71 0.73
38 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72
39 INT151559 Atp2a1 Negative_regulation of Positive_regulation of CASP3 1 0.06 0.68 0.66
40 INT129694 Binding of Casp3 and Casp9 1 0.35 0.86 0.65
41 INT296793 Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.75 0.65
42 INT296790 Tlr9 Regulation of Bax 1 0.14 0.76 0.65
43 INT296791 Positive_regulation of Akt1 Positive_regulation of Gene_expression of Bax 1 0.11 0.8 0.65
44 INT351445 Binding of Vta1 and Positive_regulation of Casp3 1 0.01 0.39 0.64
45 INT106754 Pes1 Positive_regulation of Casp3 1 0.13 0 0.63
46 INT106752 Negative_regulation of Pes1 Positive_regulation of Casp3 1 0.12 0 0.63
47 INT11558 POMC Positive_regulation of CASP3 1 0.05 0 0.62
48 INT83706 Acyp2-ps1 Positive_regulation of Casp3 1 0.11 0 0.61
49 INT112699 Bid Regulation of Bax 1 0.25 0.51 0.61
50 INT114505 Negative_regulation of Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
51 INT114506 Hmmr Positive_regulation of Casp3 1 0.01 0.72 0.6
52 INT133320 Penk Negative_regulation of Gene_expression of Casp3 1 0.11 0.91 0.6
53 INT163376 RYBP Positive_regulation of Gene_expression of Casp3 2 0.01 0.57 0.59
54 INT112399 Olr897-ps Regulation of Gene_expression of Casp3 1 0.03 0 0.54
55 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
56 INT74517 Binding of Casp3 and Cnrip1 1 0.31 0 0.51
57 INT234609 Binding of CASP3 and IMMT 1 0.00 0.5 0.5
58 INT351446 Gria2 Negative_regulation of Casp3 1 0.02 0.37 0.47
59 INT307048 Cnr1 Positive_regulation of Casp3 1 0.08 0 0.47
60 INT238638 Gopc Negative_regulation of Gene_expression of Bax 1 0.04 0.85 0.45
61 INT116613 Lnpep Negative_regulation of Gene_expression of BAX 1 0.42 0.62 0.43
62 INT116612 Lnpep Negative_regulation of BAX 1 0.42 0.62 0.42
63 INT57236 Casp3 Positive_regulation of Prl 1 0.09 0 0.41
64 INT57235 Casp3 Positive_regulation of Localization of Prl 1 0.15 0 0.4
65 INT52960 Casp3 Negative_regulation of Positive_regulation of Ltp 1 0.02 0 0.37
66 INT145908 Pdyn Regulation of Positive_regulation of Casp3 1 0.14 0.94 0.37
67 INT172213 Binding of BAX and BCL2L1 3 0.22 4.02 0.35
68 INT155061 Stat3 Negative_regulation of Bax 1 0.22 3.71 0.34
69 INT286708 Negative_regulation of Mapk1 Negative_regulation of Casp3 1 0.12 0 0.31
70 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
71 INT166162 Ccr9 Negative_regulation of Positive_regulation of Casp3 1 0.18 1.49 0.28
72 INT237927 BCL2 Positive_regulation of BAX 2 0.24 2.22 0.26
73 INT237919 BAX Positive_regulation of Protein_catabolism of PARP1 1 0.03 1.41 0.26
74 INT148629 Binding of Cat and Casp3 1 0.08 0.09 0.26
75 INT121249 Binding of ANXA5 and CASP3 1 0.36 0.67 0.25
76 INT149713 Binding of Casp3 and Fas 1 0.40 1.09 0.25
77 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24
78 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22
79 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22
80 INT349344 Bdnf Negative_regulation of Casp3 1 0.13 0.96 0.22
81 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22
82 INT181675 Positive_regulation of Casp9 Positive_regulation of Casp3 1 0.06 0.51 0.2
83 INT315384 Adcyap1 Negative_regulation of Positive_regulation of Casp3 1 0.02 0.53 0.2
84 INT181677 Casp9 Positive_regulation of Casp3 1 0.06 0.5 0.19
85 INT261387 Nsdhl Negative_regulation of Casp3 1 0.03 1.08 0.19
86 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
87 INT351442 Gria2 Regulation of Gene_expression of Casp3 1 0.01 0 0.18
88 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
89 INT155063 Csf2 Negative_regulation of Gene_expression of Bax 1 0.27 1.46 0.18
90 INT155066 Csf2 Negative_regulation of Bax 1 0.12 1.89 0.17
91 INT349475 Regulation of Bax Regulation of Bcl2 1 0.07 1.35 0.17
92 INT155232 TXNIP Regulation of BAX 1 0.23 0.15 0.17
93 INT96416 CYC1 Positive_regulation of Casp3 1 0.02 0.96 0.17
94 INT336891 Epo Negative_regulation of Transcription of Bax 1 0.10 0.68 0.16
95 INT149095 PITX2 Positive_regulation of Casp3 1 0.00 1.51 0.15
96 INT349476 Bax Regulation of Bcl2 1 0.07 1.33 0.15
97 INT292748 Akt1 Negative_regulation of Positive_regulation of Casp3 1 0.01 1.81 0.15
98 INT130918 HMHA1 Positive_regulation of BAX 1 0.04 1.37 0.14
99 INT226205 Negative_regulation of Akt1 Positive_regulation of Casp3 1 0.04 0.71 0.14
100 INT273040 Vip Regulation of Bax 1 0.23 1.69 0.13
101 INT275397 Binding of ITIH4 and Casp3 1 0.02 0.64 0.13
102 INT273041 Adcyap1 Regulation of Bax 1 0.21 1.69 0.13
103 INT252631 Binding of Casp3 and Tnfrsf1a 1 0.10 0.69 0.13
104 INT275389 Binding of Casp3 and Htatsf1 1 0.00 0.64 0.13
105 INT226192 Protein_catabolism of Bax Positive_regulation of Gtf3a 1 0.00 0.53 0.12
106 INT252632 Binding of Casp3 and Tradd 1 0.11 0.68 0.12
107 INT349345 Bdnf Negative_regulation of Positive_regulation of Casp3 1 0.13 1.02 0.12
108 INT201754 CASP8 Positive_regulation of Casp3 1 0.00 0.47 0.12
109 INT315391 IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
110 INT315390 Positive_regulation of IFNA1 Positive_regulation of Casp3 1 0.00 0.1 0.12
111 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11
112 INT142961 Binding of Nfkb1 and Casp3 1 0.00 1.02 0.11
113 INT234062 Nes Positive_regulation of Casp3 1 0.18 0.08 0.11
114 INT265890 BCL2 Regulation of Gene_expression of BAX 1 0.04 1.08 0.1
115 INT265889 BAX Regulation of Gene_expression of BAD 1 0.06 1.08 0.1
116 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1
117 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
118 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07
119 INT340401 Positive_regulation of Bax Positive_regulation of Binding of Hrk 1 0.01 0.79 0.07
120 INT203849 Ass1 Positive_regulation of Casp3 1 0.00 0.71 0.07
121 INT340395 Binding of Bax and Tg(CAG-EGFP)D4Nagy 1 0.02 0.43 0.07
122 INT175966 Kctd1 Negative_regulation of Positive_regulation of CASP3 1 0.09 0.82 0.06
123 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
124 INT302175 BAX Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
125 INT302129 BAX Regulation of Positive_regulation of CASP3 1 0.02 0.69 0.06
126 INT344254 Binding of PARP1 and CASP3 1 0.06 0.94 0.06
127 INT211347 Binding of Sigmar1 and Positive_regulation of Casp3 1 0.12 0.92 0.06
128 INT302162 CASP8 Positive_regulation of CASP3 2 0.01 2.07 0.04
129 INT242411 Mch Positive_regulation of Casp3 1 0.09 0.15 0.04
130 INT234379 BAX Positive_regulation of CASP3 1 0.04 1.16 0.04
131 INT302983 Fadd Positive_regulation of Casp3 1 0.15 1.13 0.04
132 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
133 INT242413 Regulation of Mch Positive_regulation of Casp3 1 0.05 0.16 0.04
134 INT340394 Binding of Bax and Bbc3 1 0.01 0.36 0.04
135 INT267217 Gene_expression of Hspb8 Negative_regulation of Positive_regulation of Casp3 1 0.14 2.8 0.04
136 INT322358 Binding of Parp1 and Casp3 1 0.05 1.08 0.04
137 INT172902 Binding of Bax and Bcl2 5 0.30 3.19 0.03
138 INT193778 ITIH4 Positive_regulation of CASP3 1 0.03 0.98 0.03
139 INT297737 Cbr1 Positive_regulation of Bax 1 0.06 0.53 0.03
140 INT175946 RSF1 Positive_regulation of Positive_regulation of CASP3 1 0.01 0.41 0.03
141 INT172897 Negative_regulation of Lox Positive_regulation of Positive_regulation of Casp3 1 0.04 1.19 0.03
142 INT238395 BAX Regulation of CDKN1A 1 0.03 0.31 0.03
143 INT172910 Lox Positive_regulation of Positive_regulation of Casp3 1 0.03 1.19 0.03
144 INT333259 Bcl2 Regulation of Bax 1 0.03 0.32 0.03
145 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03
146 INT345350 Casp3 Positive_regulation of Prkcd 1 0.05 0.79 0.03
147 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03
148 INT341376 Sod2 Regulation of Bax 1 0.09 0.99 0.03
149 INT185852 Binding of BAK1 and BAX 3 0.29 2.5 0
150 INT178861 Binding of BAX and BCL2 3 0.27 3.07 0
151 INT172906 Binding of Bax and Bcl2l1 2 0.16 2.03 0
152 INT198011 Binding of BAX and MCL1 2 0.20 3.04 0
153 INT327981 CASP9 Positive_regulation of CASP3 2 0.29 1.34 0
154 INT277693 Stat6 Positive_regulation of Positive_regulation of Casp3 1 0.01 1.01 0
155 INT333772 Positive_regulation of Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
156 INT348532 TP63 Positive_regulation of CASP3 1 0.04 0.55 0
157 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0
158 INT279798 APAF1 Positive_regulation of CASP3 1 0.01 1 0
159 INT333696 Tpsg1 Positive_regulation of Casp3 1 0.08 3.18 0
160 INT157755 Tmx1 Regulation of Positive_regulation of Casp3 1 0.15 0 0
161 INT277691 Cdkn1a Negative_regulation of Positive_regulation of Casp3 1 0.00 1.01 0
162 INT285029 Binding of Bax and Bcl2l1 1 0.25 0.1 0
163 INT330047 Binding of Bax and Bcl2l11 1 0.13 0.62 0
164 INT191058 Binding of Bcl2 and Positive_regulation of Gene_expression of Bax 1 0.21 0.49 0
165 INT349220 Binding of CASP3 and CD8A 1 0.00 0.18 0
166 INT327971 PNLIP Positive_regulation of Gene_expression of BAX 1 0.43 1.95 0
167 INT292500 Mlph Regulation of Gene_expression of BAX 1 0.00 0.4 0
168 INT106380 ARSA Regulation of Gene_expression of BAX 1 0.06 0.12 0
169 INT186096 EGF Regulation of Positive_regulation of CASP3 1 0.01 0.28 0
170 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0
171 INT321400 VEGFA Negative_regulation of Gene_expression of BAX 1 0.03 0.75 0
172 INT242483 Negative_regulation of Ciapin1 Negative_regulation of Positive_regulation of Bax 1 0.17 1.76 0
173 INT333771 Casp3 Positive_regulation of Gga3 1 0.05 0.5 0
174 INT136914 Mapk8 Positive_regulation of Localization of Bax 1 0.51 0.12 0
175 INT322664 Prdm8 Positive_regulation of Gene_expression of Bax 1 0.01 1.1 0
176 INT327972 Negative_regulation of BCL2 Positive_regulation of BAX 1 0.22 0.82 0
177 INT285028 Binding of Bcl2 and Bax 1 0.32 0.1 0
178 INT327982 PNLIP Regulation of Gene_expression of CASP3 1 0.13 0.58 0
179 INT167401 Ros1 Positive_regulation of CASP3 1 0.15 0.71 0
180 INT229821 Fos Positive_regulation of Bax 1 0.15 0.27 0
181 INT226042 Binding of Casp1 and Casp3 1 0.02 0.73 0
182 INT309517 Binding of Bax and Xrcc6 1 0.15 0.5 0
183 INT201761 BIK Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
184 INT113343 Phosphorylation of TP53 Positive_regulation of Gene_expression of BAX 1 0.11 0.14 0
185 INT292456 AKT1 Regulation of BAX 1 0.00 0.76 0
186 INT330052 Binding of Bax and Bid 1 0.15 0.62 0
187 INT322662 Binding of Bax and Pbrm1 1 0.08 0.9 0
188 INT172908 Binding of Bad and Bax 1 0.01 1.34 0
189 INT330057 Bid Positive_regulation of Bax 1 0.19 0.62 0
190 INT268633 Mpz Positive_regulation of Positive_regulation of Casp3 1 0.14 0 0
191 INT157754 Tmx1 Regulation of Gene_expression of Casp3 1 0.15 0 0
192 INT185855 Binding of BAX and BIK 1 0.29 0.65 0
193 INT313426 Positive_regulation of Ppp2ca Positive_regulation of Bax 1 0.46 0.36 0
194 INT267252 Bax Regulation of Bak1 1 0.05 1.09 0
195 INT201765 Binding of BCL2L1 and Bax 1 0.00 0.28 0
196 INT336036 Positive_regulation of CASP9 Positive_regulation of CASP3 1 0.05 0.75 0
197 INT237918 BID Positive_regulation of Gene_expression of BAX 1 0.04 1.31 0
198 INT201763 BID Positive_regulation of Positive_regulation of Bax 1 0.01 0.43 0
199 INT229809 Fos Regulation of Casp3 1 0.06 0.32 0
200 INT242476 Negative_regulation of Ciapin1 Positive_regulation of Bax 1 0.19 1.29 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for nuclear fragmentation involved in apoptotic nuclear change. They are ordered first by their pain relevance and then by number of times they were reported in nuclear fragmentation involved in apoptotic nuclear change. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07
2 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03
3 INT14151 Gene_expression of Casp3 311 0.78 140.26 120.68
4 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43
5 INT22546 Positive_regulation of Gene_expression of Casp3 97 0.70 47.89 51.92
6 INT49552 Negative_regulation of Positive_regulation of Casp3 76 0.55 36.04 44.78
7 INT27493 Negative_regulation of Casp3 114 0.56 56.89 44.63
8 INT11560 Positive_regulation of CASP3 236 0.70 184.33 39.38
9 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32
10 INT65598 Negative_regulation of Positive_regulation of Casp3 45 0.59 18.36 28.59
11 INT90313 Negative_regulation of Gene_expression of Casp3 57 0.57 22.23 26.77
12 INT100423 Gene_expression of Bax 141 0.75 98.43 24.48
13 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7
14 INT29704 Regulation of Casp3 51 0.56 22.13 22.79
15 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94
16 INT78694 Positive_regulation of Gene_expression of Casp3 46 0.66 18.64 19.62
17 INT22547 Regulation of Gene_expression of Casp3 23 0.62 8.04 16.78
18 INT108588 Gene_expression of CASP3 126 0.78 84.49 16.2
19 INT78697 Negative_regulation of Gene_expression of Casp3 33 0.57 11.22 16.16
20 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36
21 INT81626 Positive_regulation of Positive_regulation of Casp3 34 0.69 16.75 12.18
22 INT78695 Regulation of Casp3 24 0.44 9.43 10.48
23 INT29705 Regulation of Positive_regulation of Casp3 13 0.48 5.37 10.45
24 INT102110 Positive_regulation of Gene_expression of Bax 42 0.67 35.77 9.51
25 INT102106 Positive_regulation of Bax 48 0.67 30.62 9.28
26 INT73596 Positive_regulation of Gene_expression of BAX 43 0.67 40.97 9.22
27 INT105103 Regulation of Gene_expression of Casp3 11 0.39 3.15 9.22
28 INT78696 Regulation of Positive_regulation of Casp3 9 0.39 2.93 8.2
29 INT73595 Positive_regulation of BAX 61 0.61 56.97 7.82
30 INT98178 Localization of Casp3 32 0.65 21.01 7.77
31 INT102107 Negative_regulation of Gene_expression of Bax 30 0.57 29.48 7.33
32 INT102814 Negative_regulation of CASP3 46 0.43 28.54 6.94
33 INT102749 Positive_regulation of Positive_regulation of CASP3 32 0.67 26.07 6.93
34 INT108585 Positive_regulation of Gene_expression of CASP3 35 0.70 28.37 6.45
35 INT98837 Positive_regulation of Bax 72 0.61 63.14 6.41
36 INT57232 Binding of Casp3 22 0.36 9.42 6.2
37 INT134544 Negative_regulation of Positive_regulation of CASP3 23 0.57 18.48 5.95
38 INT145929 Regulation of Bax 20 0.60 18.12 5.35
39 INT109513 Positive_regulation of Gene_expression of Bax 37 0.67 29.52 5.06
40 INT99504 Negative_regulation of Bax 19 0.56 8.89 4.44
41 INT101858 Negative_regulation of BAX 25 0.57 23.77 4.16
42 INT84686 Regulation of BAX 26 0.49 28.54 4.13
43 INT123752 Regulation of Bax 19 0.60 16.45 4
44 INT112692 Localization of Bax 31 0.80 20.97 3.98
45 INT88805 Protein_catabolism of CASP3 24 0.86 18.38 3.7
46 INT97126 Regulation of CASP3 9 0.40 8.15 3.6
47 INT124579 Localization of BAX 35 0.78 30.31 3.43
48 INT137656 Negative_regulation of Binding of Casp3 4 0.21 0.7 3.09
49 INT88852 Protein_catabolism of Casp3 28 0.65 23.57 2.74
50 INT131112 Phosphorylation of Casp3 7 0.63 4.1 2.46
51 INT102146 Phosphorylation of Bax 4 0.66 3.48 2.35
52 INT31118 Localization of Casp3 17 0.73 11.55 2.3
53 INT108589 Negative_regulation of Gene_expression of CASP3 13 0.57 10.52 2.14
54 INT103966 Negative_regulation of Gene_expression of BAX 9 0.56 7.95 2.14
55 INT77627 Regulation of Gene_expression of BAX 14 0.44 15.09 2.12
56 INT98176 Positive_regulation of Localization of Casp3 7 0.33 6.85 2.12
57 INT154970 Localization of Bax 15 0.74 11.12 2.11
58 INT98836 Transcription of Bax 6 0.69 5.04 1.96
59 INT134442 Transcription of Bax 14 0.67 7.6 1.9
60 INT135540 Negative_regulation of Bax 16 0.48 11.8 1.89
61 INT134443 Binding of Bax 10 0.47 5.62 1.84
62 INT104883 Positive_regulation of Positive_regulation of Bax 4 0.45 4.05 1.74
63 INT102532 Protein_catabolism of Casp3 24 0.64 16.78 1.64
64 INT106749 Negative_regulation of Negative_regulation of Casp3 6 0.34 5.12 1.48
65 INT146785 Positive_regulation of Localization of Bax 7 0.69 6.16 1.47
66 INT109512 Negative_regulation of Gene_expression of Bax 12 0.42 8.04 1.44
67 INT140843 Regulation of Phosphorylation of Casp3 1 0.25 0.37 1.44
68 INT171690 Transcription of Casp3 8 0.55 2.62 1.36
69 INT97943 Positive_regulation of Protein_catabolism of Casp3 7 0.28 7.4 1.35
70 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3
71 INT154969 Positive_regulation of Localization of Bax 4 0.64 3.42 1.27
72 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2
73 INT141189 Negative_regulation of Transcription of Bax 1 0.41 1.42 1.14
74 INT102845 Localization of CASP3 7 0.81 2.81 1.06
75 INT175507 Regulation of Gene_expression of Bax 13 0.50 10.91 0.95
76 INT98134 Binding of BAX 17 0.39 11.45 0.93
77 INT31117 Binding of Casp3 14 0.23 5.27 0.93
78 INT137512 Positive_regulation of Positive_regulation of BAX 5 0.49 4.91 0.85
79 INT131105 Positive_regulation of Negative_regulation of Casp3 3 0.29 3.15 0.84
80 INT144697 Regulation of Gene_expression of Bax 8 0.37 9.5 0.81
81 INT82896 Transcription of BAX 3 0.67 4.61 0.8
82 INT148984 Positive_regulation of Localization of BAX 6 0.48 5.29 0.77
83 INT181667 Regulation of Regulation of Casp3 1 0.22 1.7 0.77
84 INT129490 Negative_regulation of Protein_catabolism of Casp3 4 0.22 3.91 0.71
85 INT351454 Regulation of Transcription of Casp3 1 0.02 0.51 0.67
86 INT131976 Positive_regulation of Protein_catabolism of CASP3 4 0.49 3.76 0.64
87 INT242061 Positive_regulation of Negative_regulation of Casp3 3 0.09 1.7 0.58
88 INT181673 Negative_regulation of Transcription of Casp3 3 0.34 0.61 0.55
89 INT176242 Binding of Bax 10 0.42 10.18 0.52
90 INT102108 Protein_catabolism of Bax 8 0.64 5.69 0.48
91 INT134446 Positive_regulation of Binding of Bax 1 0.49 0.72 0.48
92 INT229243 Negative_regulation of Phosphorylation of BAX 1 0.18 2.32 0.47
93 INT129144 Regulation of Localization of Casp3 1 0.26 0.84 0.44
94 INT153436 Positive_regulation of Localization of Casp3 3 0.49 2.12 0.43
95 INT132496 Regulation of Gene_expression of CASP3 6 0.20 4.59 0.42
96 INT152059 Regulation of Transcription of Bax 1 0.26 0.07 0.42
97 INT105888 Phosphorylation of BAX 9 0.80 4.78 0.4
98 INT155293 Positive_regulation of Protein_catabolism of Casp3 3 0.45 1.7 0.4
99 INT135802 Positive_regulation of Negative_regulation of Bax 2 0.41 0.57 0.4
100 INT229233 Positive_regulation of Phosphorylation of BAX 1 0.21 1.94 0.38
101 INT204069 Negative_regulation of Positive_regulation of Bax 5 0.31 3.08 0.34
102 INT169538 Negative_regulation of Localization of Bax 3 0.49 1.41 0.34
103 INT165916 Negative_regulation of Localization of Casp3 2 0.41 2.41 0.34
104 INT184482 Positive_regulation of Positive_regulation of Bax 5 0.41 4.7 0.33
105 INT221191 Negative_regulation of Localization of Bax 4 0.38 2.85 0.33
106 INT109530 Negative_regulation of Positive_regulation of BAX 3 0.42 3.01 0.3
107 INT82900 Positive_regulation of Transcription of BAX 2 0.49 1.86 0.29
108 INT102111 Positive_regulation of Protein_catabolism of Bax 2 0.45 1.14 0.27
109 INT159320 Negative_regulation of Protein_catabolism of CASP3 1 0.21 0.59 0.27
110 INT172227 Regulation of Localization of BAX 3 0.26 4.79 0.24
111 INT141820 Positive_regulation of Binding of Casp3 1 0.12 0.55 0.24
112 INT135543 Negative_regulation of Positive_regulation of Bax 5 0.30 6.4 0.23
113 INT187553 Regulation of Transcription of BAX 1 0.37 1.21 0.21
114 INT195018 Regulation of Negative_regulation of Casp3 1 0.21 0.48 0.2
115 INT300463 Regulation of Regulation of Bax 1 0.29 1.33 0.18
116 INT178607 Binding of CASP3 5 0.19 1.06 0.16
117 INT123522 Phosphorylation of Casp3 3 0.80 1.36 0.14
118 INT226041 Positive_regulation of Binding of Casp3 1 0.12 0.82 0.12
119 INT133486 Negative_regulation of Binding of BAX 1 0.15 0.62 0.12
120 INT336888 Negative_regulation of Transcription of Bax 1 0.07 0.68 0.11
121 INT190821 Positive_regulation of Negative_regulation of CASP3 1 0.06 0.51 0.1
122 INT304137 Regulation of Localization of Bax 2 0.24 1.7 0.09
123 INT171688 Positive_regulation of Transcription of Casp3 3 0.28 1.16 0.08
124 INT303976 Negative_regulation of Protein_catabolism of BAX 1 0.09 0.24 0.07
125 INT288609 Regulation of Regulation of Casp3 1 0.05 0.69 0.07
126 INT303978 Protein_catabolism of BAX 1 0.13 0.24 0.07
127 INT307466 Positive_regulation of Phosphorylation of Bax 1 0.15 0.76 0.07
128 INT268622 Regulation of Negative_regulation of Bax 1 0.12 0.81 0.05
129 INT333205 Negative_regulation of Protein_catabolism of Casp3 1 0.04 0.6 0.05
130 INT309494 Negative_regulation of Binding of Bax 2 0.38 1.31 0.04
131 INT172226 Positive_regulation of Negative_regulation of BAX 2 0.48 1.51 0.04
132 INT340387 Regulation of Positive_regulation of Bax 1 0.27 0.61 0.04
133 INT310746 Negative_regulation of Regulation of BAX 1 0.35 1.33 0.04
134 INT265483 Phosphorylation of CASP3 1 0.22 0.25 0.04
135 INT340390 Regulation of Binding of Bax 1 0.54 0.59 0.04
136 INT123525 Phosphorylation of Bax 3 0.41 1.18 0.03
137 INT302234 Negative_regulation of Localization of BAX 2 0.24 2.07 0.03
138 INT238508 Regulation of Regulation of BAX 1 0.21 1.5 0.03
139 INT176247 Positive_regulation of Phosphorylation of Bax 1 0.12 0.42 0.03
140 INT238497 Positive_regulation of Regulation of BAX 1 0.22 1.5 0.03
141 INT243797 Transcription of CASP3 2 0.09 0.82 0
142 INT348502 Regulation of Negative_regulation of CASP3 1 0.09 0.38 0
143 INT330041 Positive_regulation of Regulation of Bax 1 0.29 1.63 0
144 INT185897 Positive_regulation of Binding of BAX 1 0.41 0.73 0
145 INT333213 Regulation of Transcription of Bax 1 0.11 0.14 0
146 INT304140 Regulation of Negative_regulation of Casp3 1 0.05 0.67 0
147 INT237443 Positive_regulation of Phosphorylation of Casp3 1 0.39 0.09 0
148 INT159172 Negative_regulation of Negative_regulation of Casp3 1 0.09 0.07 0
149 INT322640 Positive_regulation of Binding of Bax 1 0.12 0.88 0
150 INT302247 Regulation of Binding of BAX 1 0.16 1.15 0
151 INT234056 Positive_regulation of Transcription of Bax 1 0.35 0.36 0
152 INT228785 Positive_regulation of Transcription of Casp3 1 0.17 0.06 0
153 INT242155 Negative_regulation of Localization of Casp3 1 0.04 0.25 0
154 INT228792 Transcription of Casp3 1 0.24 0.05 0
155 INT208466 Positive_regulation of Localization of CASP3 1 0.01 0.98 0
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