GO:0030279

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Name negative regulation of ossification
Categary Process
Go Slim No
Go Link GO:0030279
Unique Molecular Interactions 1041
Total Molecular Interactions 1559
Total Single Events 22470
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of ossification. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of ossification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
6 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
7 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
8 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
9 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
10 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
11 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
12 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
13 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
14 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
15 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
16 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
17 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
18 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
19 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
20 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
21 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
22 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
23 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
24 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
25 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
26 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
27 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
28 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
29 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
30 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
31 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
32 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
33 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
34 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
35 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
36 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
37 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
38 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
39 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
40 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
41 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
42 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
43 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
44 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
45 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
46 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
47 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
48 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
49 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
50 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
51 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
52 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
53 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
54 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
55 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
56 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
57 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
58 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
59 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
60 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
61 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
62 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
63 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
64 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
65 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
66 INT156008 Bcl2 Regulation of Localization of Aifm1 1 0.17 1.92 1.47
67 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
68 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
69 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
70 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
71 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
72 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
73 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
74 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
75 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
76 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
77 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
78 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
79 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
80 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
81 INT106850 P2ry2 Positive_regulation of Phosphorylation of Creb1 2 0.49 0.73 1.36
82 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
83 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
84 INT145930 ecs Positive_regulation of Gene_expression of Bcl2 1 0.01 2.06 1.34
85 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
86 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
87 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
88 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
89 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
90 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
91 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
92 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
93 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
94 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
95 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
96 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
97 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
98 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
99 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
100 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
101 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
102 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
103 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
104 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
105 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
106 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
107 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
108 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
109 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
110 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
111 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
112 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
113 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
114 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
115 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
116 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
117 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
118 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
119 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
120 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
121 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
122 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
123 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
124 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
125 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
126 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
127 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
128 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
129 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
130 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
131 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
132 INT352295 Binding of P2RY2 and Agtr1a 1 0.01 0.08 1.02
133 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
134 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
135 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
136 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
137 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
138 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
139 INT142202 FL Positive_regulation of Bcl2 1 0.05 0.39 0.99
140 INT61637 Binding of P2ry2 and Gtpbp4 1 0.02 0.1 0.99
141 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
142 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
143 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
144 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
145 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
146 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
147 INT352447 Gse1 Negative_regulation of Gene_expression of Calca 1 0.03 0.98 0.94
148 INT24938 TAC1 Regulation of Calca 1 0.22 0.35 0.94
149 INT24939 TAC3 Regulation of Calca 1 0.01 0.35 0.94
150 INT331109 Tpnr1 Regulation of Gene_expression of Calca 1 0.06 0.97 0.94
151 INT248186 Cxcl1 Positive_regulation of Localization of CALCA 1 0.39 0.88 0.93
152 INT28656 Calca Negative_regulation of Localization of Gnrhr 1 0.19 0 0.91
153 INT112765 Binding of Nfkb1 and Bcl2 1 0.00 1.37 0.91
154 INT53155 Rac1 Positive_regulation of Gene_expression of Calca 1 0.06 0 0.89
155 INT63943 Il1b Positive_regulation of Localization of Calca 2 0.46 0.98 0.88
156 INT53153 fut10 Positive_regulation of Gene_expression of Calca 1 0.01 0 0.88
157 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
158 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
159 INT28655 Calca Negative_regulation of Localization of Gh1 1 0.34 0 0.88
160 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
161 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
162 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
163 INT213976 Calca Negative_regulation of Gene_expression of Il2 1 0.03 0.25 0.86
164 INT166634 Binding of Bcl2 and Becn1 1 0.20 0.5 0.86
165 INT150864 RYBP Positive_regulation of Positive_regulation of Bcl2 1 0.01 0.66 0.86
166 INT113542 Binding of Calca and Adarb1 2 0.00 0.44 0.85
167 INT351323 Nts Regulation of Localization of Calca 1 0.01 0.6 0.85
168 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
169 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
170 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
171 INT28654 Calca Regulation of Localization of Gh1 1 0.36 0 0.84
172 INT342991 HCL1 Positive_regulation of CALCA 1 0.03 0.71 0.84
173 INT111363 TRPV1 Positive_regulation of Localization of Calca 1 0.11 0 0.83
174 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
175 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
176 INT225691 TRPV1 Positive_regulation of Localization of CALCA 1 0.18 0.7 0.83
177 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
178 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
179 INT87490 CALCA Positive_regulation of Gene_expression of CCL5 1 0.30 0.14 0.81
180 INT103178 Mastl Positive_regulation of Localization of Calca 1 0.13 0.36 0.81
181 INT87494 CALCA Positive_regulation of IL8 1 0.48 0.15 0.81
182 INT86150 Inhba Positive_regulation of Gene_expression of Calca 1 0.09 0.61 0.81
183 INT87489 CALCA Positive_regulation of Gene_expression of CCL2 1 0.43 0.14 0.81
184 INT87492 CALCA Regulation of IL8 1 0.28 0.15 0.81
185 INT213972 Calca Regulation of Mthfd1 1 0.05 0.19 0.8
186 INT109142 Calca Positive_regulation of Transcription of Creb1 1 0.47 0.13 0.8
187 INT118010 Binding of CALCA and CD177 1 0.06 0.6 0.8
188 INT131646 Ngf Positive_regulation of Localization of Calca 1 0.21 0.35 0.8
189 INT180782 Bdnf Positive_regulation of Calca 1 0.16 0.77 0.8
190 INT86151 Olr1745 Positive_regulation of Gene_expression of Calca 1 0.51 0.6 0.8
191 INT60102 Adora1 Regulation of Localization of Calca 1 0.46 0 0.79
192 INT111361 Cnr1 Negative_regulation of Localization of Calca 1 0.01 0 0.78
193 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
194 INT298457 Binding of Calca and Npr1 1 0.01 0.39 0.77
195 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
196 INT96783 Positive_regulation of Binding of CALCA and Calca 1 0.29 0.17 0.77
197 INT224283 Bdnf Regulation of Gene_expression of Calca 1 0.19 0.35 0.76
198 INT87493 Binding of CALCA and Positive_regulation of Gene_expression of IL8 1 0.52 0.18 0.76
199 INT109141 Calca Positive_regulation of Creb1 1 0.47 0.13 0.76
200 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of ossification. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of ossification. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
8 INT626 Localization of CALCA 289 0.81 125.39 221.15
9 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
10 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
11 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
12 INT2541 Binding of Calca 200 0.48 67.14 134.62
13 INT5008 Localization of Calca 204 0.81 80.35 125.16
14 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
15 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
16 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
17 INT6761 Binding of CALCA 100 0.48 26.71 62.05
18 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
19 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
20 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
21 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03
22 INT4891 Transcription of Calca 81 0.72 35.27 53.75
23 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
24 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
25 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
26 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
27 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
28 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38
29 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
30 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
31 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73
32 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
33 INT22499 Regulation of Calca 42 0.62 17.32 28.02
34 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
35 INT37889 Gene_expression of P2ry2 75 0.65 26.01 23.8
36 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
37 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
38 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
39 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46
40 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
41 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37
42 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
43 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
44 INT61635 Positive_regulation of P2ry2 35 0.56 12.08 14.68
45 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
46 INT80222 Negative_regulation of Bcl2 82 0.58 69.16 13.18
47 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
48 INT26217 Binding of Calca 22 0.48 5.22 12.57
49 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
50 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
51 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
52 INT81640 Positive_regulation of Gene_expression of Bcl2 106 0.69 84.58 11.63
53 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
54 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
55 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
56 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
57 INT105816 Gene_expression of P2RY2 53 0.78 16.47 9.67
58 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
59 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
60 INT70017 Positive_regulation of BCL2 87 0.67 66.62 8.68
61 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37
62 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
63 INT65959 Positive_regulation of Gene_expression of BCL2 75 0.70 77.3 8.27
64 INT80220 Positive_regulation of Bcl2 71 0.58 57.73 7.86
65 INT77306 Negative_regulation of Gene_expression of Bcl2 46 0.58 38.05 7.71
66 INT91445 Regulation of Bcl2 50 0.56 38.8 7.41
67 INT111680 Gene_expression of P2ry2 20 0.58 9.23 7.39
68 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
69 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
70 INT76253 Positive_regulation of P2RY2 29 0.70 13.99 7.33
71 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
72 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
73 INT95466 Regulation of P2ry2 23 0.56 3.66 6.86
74 INT93101 Regulation of Gene_expression of Bcl2 26 0.62 18.45 6.71
75 INT84685 Regulation of BCL2 67 0.60 72.96 6.65
76 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
77 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
78 INT86982 Transcription of Calca 9 0.69 2.98 5.74
79 INT100422 Negative_regulation of Gene_expression of Bcl2 46 0.58 28.86 5.7
80 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
81 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
82 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
83 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
84 INT70613 Negative_regulation of Gene_expression of BCL2 48 0.59 38.91 5.22
85 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
86 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
87 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
88 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
89 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
90 INT73262 Negative_regulation of BCL2 67 0.57 61.01 5.07
91 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
92 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
93 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
94 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
95 INT112038 Positive_regulation of P2ry2 8 0.45 2.41 4.4
96 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
97 INT101957 Transcription of Bcl2 30 0.69 16.57 4.3
98 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
99 INT126659 Gene_expression of Tph1 22 0.78 2.04 4.04
100 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
101 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
102 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
103 INT105882 Phosphorylation of Bcl2 11 0.59 8.15 3.73
104 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
105 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
106 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
107 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
108 INT118270 Regulation of P2RY2 16 0.45 7.02 3.45
109 INT109403 Regulation of Gene_expression of BCL2 31 0.60 31.22 3.4
110 INT126560 Binding of P2RY2 12 0.44 6.43 3.4
111 INT16626 Positive_regulation of Adrb2 10 0.30 2.41 3.4
112 INT102347 Localization of P2ry2 4 0.56 1.23 3.31
113 INT68445 Gene_expression of ENPP1 10 0.70 10.8 3.3
114 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
115 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
116 INT81642 Regulation of Gene_expression of Bcl2 20 0.44 16.93 3.19
117 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
118 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16
119 INT51151 Positive_regulation of Regulation of Calca 8 0.50 1.77 3.08
120 INT105884 Binding of Bcl2 19 0.35 15.67 3
121 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
122 INT207851 Regulation of Enpp1 5 0.45 4.42 2.96
123 INT41474 Gene_expression of ADRB2 10 0.75 1.56 2.94
124 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
125 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9
126 INT60672 Regulation of Gene_expression of CALCA 3 0.61 1.76 2.85
127 INT95720 Phosphorylation of Calca 2 0.80 2.04 2.8
128 INT57354 Positive_regulation of Positive_regulation of Calca 3 0.60 1.42 2.78
129 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
130 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
131 INT8840 Positive_regulation of Positive_regulation of CALCA 8 0.50 1.8 2.74
132 INT91284 Negative_regulation of P2ry2 8 0.25 2.66 2.71
133 INT19292 Protein_catabolism of CALCA 7 0.76 0.8 2.53
134 INT107846 Transcription of P2ry2 6 0.46 2.06 2.52
135 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
136 INT514 Gene_expression of Adrb2 3 0.53 0.23 2.46
137 INT150465 Positive_regulation of Gene_expression of P2ry2 3 0.56 3.48 2.33
138 INT147349 Localization of Bcl2 13 0.65 7.83 2.31
139 INT137977 Localization of P2RY2 5 0.80 3.07 2.27
140 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25
141 INT142677 Negative_regulation of Positive_regulation of Bcl2 4 0.36 3.09 2.24
142 INT107597 Binding of Enpp1 5 0.37 3.35 2.23
143 INT151816 Negative_regulation of P2ry2 3 0.02 3.1 2.23
144 INT70725 Negative_regulation of Binding of ADRB2 3 0.57 0.4 2.14
145 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
146 INT58752 Positive_regulation of Binding of CALCA 3 0.49 0.73 2.09
147 INT152902 Positive_regulation of Transcription of CALCA 5 0.66 0.99 2.07
148 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03
149 INT54986 Negative_regulation of Positive_regulation of Calca 2 0.43 0.93 2.02
150 INT316778 Positive_regulation of Gene_expression of ENPP1 1 0.62 7.2 1.97
151 INT24291 Positive_regulation of Negative_regulation of CALCA 3 0.61 0.67 1.91
152 INT95467 Transcription of P2ry2 7 0.49 1.43 1.87
153 INT101108 Localization of Bcl2 16 0.72 11.68 1.86
154 INT105883 Positive_regulation of Phosphorylation of Bcl2 8 0.32 5.67 1.86
155 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
156 INT102288 Localization of P2ry2 4 0.55 1.02 1.83
157 INT224529 Positive_regulation of Gene_expression of Enpp1 15 0.70 12.75 1.81
158 INT40832 Localization of ADRB2 5 0.73 2.21 1.81
159 INT102348 Regulation of P2ry2 6 0.40 2.18 1.79
160 INT140113 Gene_expression of Gfra4 5 0.37 2.57 1.76
161 INT101958 Positive_regulation of Transcription of Bcl2 4 0.50 2.22 1.65
162 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
163 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
164 INT241566 Negative_regulation of Negative_regulation of Calca 1 0.03 0.72 1.63
165 INT137513 Negative_regulation of Positive_regulation of BCL2 6 0.35 5.3 1.62
166 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
167 INT105815 Positive_regulation of Gene_expression of P2RY2 9 0.50 3.62 1.52
168 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
169 INT332460 Regulation of Binding of Enpp1 1 0.05 0.78 1.5
170 INT48300 Regulation of Binding of Calca 2 0.39 0.73 1.49
171 INT126660 Positive_regulation of Gene_expression of Tph1 5 0.50 0.07 1.43
172 INT52250 Positive_regulation of Regulation of CALCA 1 0.48 0.08 1.43
173 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
174 INT150466 Regulation of Positive_regulation of P2ry2 1 0.37 1.26 1.42
175 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
176 INT61636 Positive_regulation of Positive_regulation of P2ry2 4 0.34 0.13 1.4
177 INT78097 Negative_regulation of Regulation of CALCA 2 0.42 2.02 1.37
178 INT169232 Negative_regulation of Gene_expression of P2ry2 3 0.31 2.29 1.32
179 INT36588 Protein_catabolism of Calca 7 0.87 1.98 1.31
180 INT117966 Binding of P2ry2 5 0.36 0.44 1.31
181 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
182 INT101107 Positive_regulation of Localization of Bcl2 3 0.48 3.13 1.28
183 INT145413 Positive_regulation of Gfra4 1 0.22 1.97 1.27
184 INT319293 Phosphorylation of Ptk2b 9 0.80 3.14 1.24
185 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24
186 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
187 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16
188 INT41475 Positive_regulation of Localization of ADRB2 2 0.49 0.18 1.12
189 INT172855 Binding of Bcl2 37 0.32 23.41 1.09
190 INT70021 Localization of BCL2 23 0.74 21.6 1.09
191 INT119974 Negative_regulation of P2RY2 3 0.43 1.6 1.04
192 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
193 INT49796 Positive_regulation of Binding of Adrb2 1 0.00 0 1.02
194 INT52186 Positive_regulation of Positive_regulation of ADRB2 1 0.14 0 1.02
195 INT49795 Negative_regulation of Binding of Adrb2 1 0.00 0 1.02
196 INT95719 Negative_regulation of Phosphorylation of Calca 1 0.41 0.09 1.02
197 INT290411 Gene_expression of Ptk2b 10 0.65 3.72 1.01
198 INT95718 Positive_regulation of Phosphorylation of Calca 1 0.49 0.09 1.01
199 INT129577 Negative_regulation of Positive_regulation of P2ry2 4 0.29 0.45 1
200 INT216611 Regulation of Gene_expression of P2ry2 1 0.30 0.29 0.99
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