GO:0030299

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Name intestinal cholesterol absorption
Categary Process
Go Slim No
Go Link GO:0030299
Unique Molecular Interactions 95
Total Molecular Interactions 118
Total Single Events 1472
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intestinal cholesterol absorption. They are ordered first by their pain relevance and then by number of times they were reported for intestinal cholesterol absorption. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
2 INT76199 CASP1 Positive_regulation of CEL 1 0.06 0.32 1.14
3 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99
4 INT99578 Binding of CEL and Kit 1 0.04 1.07 0.81
5 INT117604 AKR1C1 Negative_regulation of Positive_regulation of Mpo 1 0.00 1.45 0.78
6 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
7 INT26648 Binding of CEL and HP 1 0.04 0 0.58
8 INT209152 Regulation of OXT Positive_regulation of PNLIP 1 0.05 0.42 0.54
9 INT334901 LDLR Positive_regulation of Crp 1 0.00 1.48 0.51
10 INT175326 SERPINH1 Regulation of Pnlip 1 0.00 0.53 0.49
11 INT160444 Tpsab1 Positive_regulation of Gene_expression of CEL 1 0.48 0.96 0.48
12 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43
13 INT219683 Binding of CEL and GOPC 1 0.04 3.11 0.38
14 INT175319 Negative_regulation of Nos2 Negative_regulation of Positive_regulation of Pnlip 1 0.01 0.83 0.34
15 INT122168 AKR1C1 Regulation of PPARG 1 0.12 0.25 0.31
16 INT17162 Binding of CEL and Lhb 1 0.06 0.38 0.3
17 INT254769 Binding of LDLR and Apoe 1 0.03 0 0.28
18 INT78296 Negative_regulation of Binding of Ptpra and Ldlr 1 0.22 0.25 0.24
19 INT78293 Binding of Apoe and Ldlr 1 0.20 0.25 0.24
20 INT78292 Negative_regulation of Binding of Apoe and Ldlr 1 0.23 0.25 0.24
21 INT78291 Binding of Ptpra and Ldlr 1 0.20 0.25 0.24
22 INT106993 CEL Positive_regulation of NR1I2 1 0.39 0.39 0.22
23 INT90772 Binding of AKR1C4 and AKR1C1 1 0.39 0.08 0.2
24 INT49057 Positive_regulation of CEL Positive_regulation of Localization of LTC4S 1 0.41 0.28 0.18
25 INT85816 Binding of CEL and TTR 1 0.39 0.77 0.14
26 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13
27 INT270723 Negative_regulation of HMGCR Positive_regulation of LDLR 1 0.02 0.52 0.12
28 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
29 INT99140 LDLR Positive_regulation of Localization of VCAM1 1 0.05 0.44 0.11
30 INT156056 AKR1C1 Negative_regulation of UMOD 1 0.03 0.41 0.1
31 INT92671 Binding of CEL and HLA-B 1 0.38 0.19 0.1
32 INT16860 Abcg5 Negative_regulation of Maob 1 0.10 0 0.1
33 INT32030 Binding of CEL and ERLEC1 1 0.08 0.42 0.1
34 INT71344 Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
35 INT66590 Gnrhr Regulation of Ldlr 1 0.02 0.4 0.06
36 INT71343 Negative_regulation of Ldlr Positive_regulation of Hdlcl1 1 0.01 0.69 0.06
37 INT133047 TNF Positive_regulation of Gene_expression of CEL 1 0.47 0.61 0.05
38 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05
39 INT288853 Binding of HSD11B1 and LDLR 1 0.26 1.52 0.04
40 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04
41 INT177350 Binding of CEL and PLA2G2A 1 0.06 0.08 0.04
42 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04
43 INT186187 LDLR Regulation of Gene_expression of SCARB1 1 0.17 1.71 0.04
44 INT294217 Binding of PLG and Ldlr 1 0.33 0.06 0.04
45 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04
46 INT294210 Binding of Ldlr and Plat 1 0.42 0.06 0.04
47 INT294206 Ldlr Positive_regulation of Grin1 1 0.26 0 0.03
48 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
49 INT177352 Binding of CEL and PTN 1 0.01 0 0.03
50 INT186186 LDLR Regulation of SCARB1 1 0.08 0.65 0.03
51 INT350257 Slc12a6 Negative_regulation of Pnlip 1 0.03 1.53 0.03
52 INT239351 Binding of CETP and Ldlr 1 0.15 1.01 0.03
53 INT251961 Binding of LDLR and SNRNP70 2 0.04 0.55 0
54 INT209984 Binding of LDLR and LRP1 1 0.08 0 0
55 INT198920 Binding of Ldlr and Lrpap1 1 0.05 0.06 0
56 INT327969 Binding of PNLIP and TNFRSF11A 1 0.09 0.89 0
57 INT327978 PNLIP Regulation of Regulation of CASP9 1 0.19 0.57 0
58 INT209987 Binding of APOE and LDLR 1 0.24 0 0
59 INT327971 PNLIP Positive_regulation of Gene_expression of BAX 1 0.43 1.95 0
60 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
61 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0
62 INT327980 PNLIP Regulation of TNFRSF11A 1 0.15 0.89 0
63 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0
64 INT327982 PNLIP Regulation of Gene_expression of CASP3 1 0.13 0.58 0
65 INT316414 Binding of LDLR and T2dm2 1 0.00 1.54 0
66 INT186189 LDLR Positive_regulation of Gene_expression of SCARB1 1 0.14 1.27 0
67 INT317842 Hdlcl1 Positive_regulation of Ldlr 1 0.00 1.11 0
68 INT302596 Eef1a2 Negative_regulation of LDLR 1 0.14 0.31 0
69 INT327973 PNLIP Negative_regulation of NFKBIB 1 0.07 0.9 0
70 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
71 INT268459 Binding of LDLR and Olr1 1 0.00 0.78 0
72 INT44885 Binding of CEL and MET 1 0.39 0.15 0
73 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
74 INT300199 PCSK9 Regulation of Gene_expression of LDLR 1 0.13 0.88 0
75 INT339699 LDLR Positive_regulation of SREBF2 1 0.08 1.08 0
76 INT198925 Binding of App and Ldlr 1 0.14 0.15 0
77 INT327976 PNLIP Negative_regulation of Gene_expression of BCL2 1 0.29 0.53 0
78 INT339694 LDLR Positive_regulation of Gene_expression of SREBF2 1 0.08 1.08 0
79 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0
80 INT353804 Binding of APOE and Ldlr 1 0.16 0.84 0
81 INT251964 Binding of LDLR and RS1 1 0.00 0.31 0
82 INT353797 Binding of Ldlr and Trf 1 0.04 0.19 0
83 INT353800 Binding of Ldlr and Cd320 1 0.29 0.83 0
84 INT312630 Agrn Positive_regulation of Ldlr 1 0.14 0.66 0
85 INT326282 BCL2L10 Negative_regulation of Pnlip 1 0.11 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for intestinal cholesterol absorption. They are ordered first by their pain relevance and then by number of times they were reported in intestinal cholesterol absorption. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58
2 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87
3 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83
4 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87
5 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05
6 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21
7 INT23245 Positive_regulation of Gene_expression of CEL 19 0.69 14.81 4.92
8 INT18995 Binding of CEL 23 0.47 14.46 4.5
9 INT4464 Localization of CEL 21 0.80 8.09 3.88
10 INT57728 Regulation of LDLR 25 0.41 13.18 3.46
11 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32
12 INT5166 Binding of Ldlr 14 0.48 11.95 3.32
13 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05
14 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04
15 INT1484 Positive_regulation of Pnlip 8 0.35 5.09 3.01
16 INT194465 Gene_expression of Ldlr 27 0.76 31.36 2.73
17 INT124322 Negative_regulation of PNLIP 11 0.31 6.53 1.88
18 INT47628 Regulation of CEL 9 0.60 4.5 1.85
19 INT36188 Positive_regulation of PNLIP 7 0.68 5.99 1.6
20 INT75694 Regulation of Gene_expression of CEL 9 0.60 6.08 1.53
21 INT175303 Positive_regulation of Pnlip 1 0.10 5.19 1.52
22 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35
23 INT36947 Gene_expression of PNLIP 13 0.45 11.04 1.23
24 INT122171 Negative_regulation of AKR1C1 5 0.59 1.92 1.22
25 INT23199 Binding of LDLR 22 0.47 17.08 1.16
26 INT38992 Negative_regulation of Pnlip 6 0.48 3.91 1.14
27 INT82703 Transcription of LDLR 6 0.64 0.4 1.13
28 INT176183 Gene_expression of Abcg5 1 0.77 5.01 1.08
29 INT82707 Positive_regulation of Transcription of LDLR 1 0.62 0.34 0.98
30 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97
31 INT82702 Positive_regulation of Positive_regulation of LDLR 4 0.45 1.08 0.95
32 INT39864 Regulation of PNLIP 2 0.10 0.74 0.85
33 INT81622 Positive_regulation of Positive_regulation of CEL 4 0.49 3.94 0.73
34 INT76127 Transcription of CEL 5 0.71 2.02 0.7
35 INT142802 Binding of Ldlr 8 0.47 5.08 0.65
36 INT157892 Binding of PNLIP 5 0.25 4.58 0.65
37 INT115276 Gene_expression of AKR1C1 11 0.77 4.65 0.63
38 INT108328 Negative_regulation of Gene_expression of CEL 6 0.57 2.56 0.63
39 INT142800 Positive_regulation of Ldlr 21 0.68 14.75 0.6
40 INT200090 Positive_regulation of Gene_expression of Ldlr 5 0.37 3.67 0.59
41 INT78999 Binding of AKR1C1 3 0.36 1.75 0.58
42 INT169489 Positive_regulation of Localization of CEL 1 0.45 0.34 0.58
43 INT209154 Negative_regulation of Positive_regulation of PNLIP 1 0.15 0.5 0.5
44 INT122170 Regulation of AKR1C1 1 0.12 0.22 0.42
45 INT42032 Localization of PNLIP 4 0.14 3.44 0.41
46 INT175306 Regulation of Pnlip 1 0.04 1.1 0.41
47 INT197012 Regulation of Gene_expression of LDLR 4 0.40 1.31 0.4
48 INT60601 Negative_regulation of Negative_regulation of CEL 1 0.41 0.34 0.4
49 INT138380 Regulation of Transcription of Ldlr 1 0.38 0.21 0.38
50 INT138379 Transcription of Ldlr 1 0.59 0.21 0.38
51 INT252223 Positive_regulation of Gene_expression of Ldlr 3 0.55 10.28 0.37
52 INT5168 Regulation of Binding of Ldlr 1 0.45 0 0.36
53 INT232235 Negative_regulation of Gene_expression of Ldlr 3 0.42 3.13 0.34
54 INT135069 Regulation of Localization of CEL 1 0.44 0 0.34
55 INT175296 Negative_regulation of Pnlip 1 0.08 2.89 0.33
56 INT38236 Gene_expression of Pnlip 2 0.29 0.89 0.31
57 INT42033 Regulation of Localization of PNLIP 1 0.00 0 0.31
58 INT352167 Negative_regulation of Positive_regulation of CEL 1 0.04 1.07 0.31
59 INT59862 Phosphorylation of CEL 2 0.70 0.53 0.3
60 INT281746 Negative_regulation of Localization of CEL 1 0.03 0.6 0.29
61 INT336270 Localization of AKR1C1 1 0.06 1.56 0.29
62 INT154494 Transcription of AKR1C1 4 0.72 0.99 0.27
63 INT197016 Positive_regulation of Gene_expression of LDLR 13 0.50 5.82 0.24
64 INT16158 Protein_catabolism of CEL 1 0.64 0 0.24
65 INT37790 Localization of Ldlr 5 0.38 2.29 0.23
66 INT74677 Localization of Pnlip 1 0.08 0.63 0.22
67 INT202425 Negative_regulation of Transcription of CEL 1 0.03 0.49 0.21
68 INT176221 Positive_regulation of Abcg5 1 0.69 0.24 0.21
69 INT252222 Regulation of Ldlr 5 0.34 4.3 0.19
70 INT5165 Positive_regulation of Binding of Ldlr 1 0.50 0 0.19
71 INT5167 Negative_regulation of Binding of Ldlr 1 0.43 0 0.17
72 INT324891 Binding of Pnlip 1 0.07 0.66 0.17
73 INT17474 Negative_regulation of Positive_regulation of LDLR 4 0.37 2.93 0.16
74 INT209992 Negative_regulation of Transcription of LDLR 2 0.29 0 0.16
75 INT87515 Negative_regulation of Gene_expression of LDLR 2 0.09 1.96 0.16
76 INT176198 Binding of Abcg5 1 0.48 0.46 0.15
77 INT153084 Positive_regulation of Gene_expression of AKR1C1 4 0.50 1.56 0.14
78 INT175305 Localization of Pnlip 1 0.11 1.01 0.14
79 INT211532 Localization of Ldlr 4 0.56 3.52 0.13
80 INT176214 Negative_regulation of Abcg5 1 0.58 1.49 0.13
81 INT215136 Regulation of Gene_expression of Ldlr 2 0.12 0.76 0.12
82 INT116739 Protein_catabolism of Ldlr 1 0.87 1.18 0.12
83 INT34582 Negative_regulation of Positive_regulation of Ldlr 2 0.03 1.33 0.1
84 INT167019 Negative_regulation of Gene_expression of Ldlr 3 0.42 0.76 0.08
85 INT274789 Positive_regulation of Gene_expression of PNLIP 1 0.03 0.24 0.08
86 INT274686 Phosphorylation of PNLIP 1 0.04 0.18 0.08
87 INT293307 Regulation of Gene_expression of Ldlr 3 0.19 2.77 0.07
88 INT175297 Regulation of Negative_regulation of Pnlip 1 0.07 0.81 0.07
89 INT177877 Positive_regulation of AKR1C1 3 0.50 1.13 0.06
90 INT348079 Negative_regulation of Negative_regulation of Ldlr 1 0.12 1.03 0.05
91 INT176189 Localization of Abcg5 1 0.79 0.64 0.04
92 INT197014 Localization of LDLR 8 0.63 3.29 0.03
93 INT297432 Positive_regulation of Localization of Ldlr 2 0.14 0.35 0.03
94 INT176203 Positive_regulation of Gene_expression of Abcg5 1 0.69 0.34 0.03
95 INT176889 Negative_regulation of Binding of LDLR 2 0.41 1.2 0
96 INT276260 Negative_regulation of Localization of LDLR 2 0.40 1.34 0
97 INT176220 Regulation of Abcg5 1 0.61 0.09 0
98 INT176210 Regulation of Gene_expression of Abcg5 1 0.45 0.29 0
99 INT350249 Transcription of Pnlip 1 0.34 0.28 0
100 INT39405 Regulation of Binding of LDLR 1 0.17 0 0
101 INT176193 Negative_regulation of Gene_expression of Abcg5 1 0.43 0.63 0
102 INT353784 Protein_catabolism of Ldlr 1 0.52 1.85 0
103 INT354554 Gene_expression of Pnlip 1 0.29 0 0
104 INT326280 Positive_regulation of Negative_regulation of Pnlip 1 0.17 0 0
105 INT332947 Positive_regulation of Negative_regulation of Ldlr 1 0.37 1.54 0
106 INT207723 Positive_regulation of Transcription of AKR1C1 1 0.33 0.68 0
107 INT178543 Regulation of Gene_expression of AKR1C1 1 0.43 0.32 0
108 INT336099 Transcription of Ldlr 1 0.25 0.36 0
109 INT352610 Regulation of Regulation of CEL 1 0.00 0.55 0
110 INT97442 Positive_regulation of Binding of CEL 1 0.67 0 0
111 INT336103 Positive_regulation of Transcription of Ldlr 1 0.22 0.47 0
112 INT176196 Negative_regulation of Transcription of Abcg5 1 0.58 0.24 0
113 INT350251 Regulation of Pnlip 1 0.12 0.87 0
114 INT170750 Negative_regulation of Negative_regulation of LDLR 1 0.07 0.93 0
115 INT176204 Transcription of Abcg5 1 0.71 0.6 0
116 INT327986 Negative_regulation of Binding of PNLIP 1 0.28 1.52 0
117 INT176171 Negative_regulation of Negative_regulation of Abcg5 1 0.42 0.42 0
118 INT268450 Protein_catabolism of LDLR 1 0.07 0.14 0
119 INT178533 Negative_regulation of Gene_expression of AKR1C1 1 0.41 0.61 0
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