GO:0030315

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Name T-tubule
Categary Component
Go Slim No
Go Link GO:0030315
Unique Molecular Interactions 472
Total Molecular Interactions 617
Total Single Events 6482
Pain Genes Associated 42

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for T-tubule. They are ordered first by their pain relevance and then by number of times they were reported for T-tubule. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT108810 Esr1 Positive_regulation of Binding of Oprm1 1 0.51 1.79 3.22
2 INT190981 Binding of Npy and Scn2a1 1 0.10 0 1.75
3 INT130838 Gfap Positive_regulation of Aqp4 1 0.51 1.9 1.56
4 INT158079 Binding of Esr1 and Gper 1 0.31 0.97 1.35
5 INT222182 Binding of ESR1 and HLA-DRB2 1 0.00 3.1 1.35
6 INT31772 Ednra Positive_regulation of Nppa 1 0.05 0.13 1.33
7 INT150890 Binding of Esr1 and Esr2 2 0.52 2.06 1.31
8 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
9 INT350862 Hist1h1t Regulation of Kcnj5 1 0.02 1.35 1.22
10 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
11 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
12 INT341479 Binding of SCN2A and SCN4A 1 0.37 1.29 0.98
13 INT341480 Binding of SCN1A and SCN4A 1 0.36 1.29 0.98
14 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97
15 INT278292 Binding of CRP and ESR1 6 0.09 10.92 0.96
16 INT123023 Ednra Regulation of Adarb1 1 0.00 0 0.93
17 INT123024 Csf2 Regulation of Ednra 1 0.06 0 0.92
18 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
19 INT75920 Slc8a1 Negative_regulation of Cpox 1 0.03 0.85 0.89
20 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
21 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
22 INT128701 Ednra Regulation of EDNRB 1 0.17 0.58 0.84
23 INT128702 Ednra Regulation of EDNRA 1 0.00 0.58 0.84
24 INT108812 Esr1 Positive_regulation of Positive_regulation of Oprm1 1 0.42 0.38 0.78
25 INT145646 Binding of Scn2a1 and Scn5a 1 0.36 0 0.76
26 INT91655 SLC8A1 Negative_regulation of CASP1 1 0.02 0.43 0.75
27 INT190986 Per1 Positive_regulation of Scn2a1 1 0.17 0 0.74
28 INT190979 Per2 Positive_regulation of Scn2a1 1 0.20 0 0.74
29 INT190984 Binding of Scn2a1 and Gria1 1 0.03 0.08 0.71
30 INT123077 Cacna1c Negative_regulation of Gene_expression of Dbi 1 0.05 0.71 0.7
31 INT134286 PLD2 Regulation of Regulation of EDNRA 1 0.10 0 0.67
32 INT38057 Binding of Crp and Esr1 2 0.04 1.21 0.65
33 INT76877 Binding of Slc3a1 and Slc8a1 1 0.02 0 0.64
34 INT219921 EDNRA Negative_regulation of Trpv1 1 0.13 0.36 0.63
35 INT219919 EDNRA Negative_regulation of Edn1 1 0.15 0.36 0.63
36 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62
37 INT215647 Adora1 Positive_regulation of Kcnj5 1 0.00 0 0.62
38 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61
39 INT309158 Binding of Esr1 and Dlat 1 0.04 1.39 0.61
40 INT28845 su Negative_regulation of Positive_regulation of Scn2a1 1 0.27 1.27 0.61
41 INT64776 Binding of Oprm1 and Kcnj3 1 0.38 0 0.6
42 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6
43 INT190987 Abat Regulation of Scn2a1 1 0.03 0.07 0.59
44 INT350859 Hist1h1t Regulation of Gene_expression of Kcnj5 1 0.02 0.37 0.59
45 INT341594 Binding of ESR1 and HLA-B 1 0.01 0.72 0.57
46 INT190988 Vip Positive_regulation of Gene_expression of Scn2a1 1 0.16 0.1 0.57
47 INT350861 Hist1h1t Positive_regulation of Gene_expression of Kcnj5 1 0.02 0.35 0.56
48 INT278824 Positive_regulation of Binding of EDNRA and EDNRB 1 0.12 1.65 0.53
49 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
50 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
51 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5
52 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5
53 INT350860 Hist1h1t Positive_regulation of Kcnj5 1 0.02 0.54 0.5
54 INT153897 Binding of KCNJ3 and Snx27 1 0.03 0.28 0.5
55 INT154014 Binding of Esr1 and Gabrg1 1 0.07 0.07 0.5
56 INT161166 Binding of Aqp4 and Igh-6 1 0.03 2.58 0.49
57 INT99571 Edn1 Positive_regulation of Localization of Ednra 1 0.01 0.32 0.47
58 INT147179 Esr1 Regulation of Gene_expression of Penk 1 0.01 0.68 0.46
59 INT219910 EDN1 Positive_regulation of Positive_regulation of EDNRA 1 0.00 0.3 0.45
60 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
61 INT94093 Pnoc Positive_regulation of EDNRA 1 0.03 0.1 0.44
62 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
63 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
64 INT53139 Binding of Htr1a and Kcnj3 1 0.37 0 0.42
65 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42
66 INT118519 Slc8a1 Negative_regulation of Positive_regulation of Nfkb1 1 0.16 0.59 0.42
67 INT60456 SCN5A Regulation of Scn2a1 1 0.00 0 0.41
68 INT261370 Nsdhl Regulation of Esr1 1 0.01 0.75 0.41
69 INT190977 Npy Regulation of Scn2a1 1 0.16 0 0.4
70 INT334763 Ednra Positive_regulation of Gabrg1 1 0.01 0 0.4
71 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39
72 INT215629 Binding of Kcnj5 and Fig4 1 0.00 0.37 0.39
73 INT190739 Adcyap1 Regulation of Gene_expression of Scn2a1 1 0.13 0 0.39
74 INT77683 Ednra Negative_regulation of LH 1 0.03 0.23 0.39
75 INT117361 Binding of Esr1 and sea 1 0.02 1.38 0.38
76 INT199974 ESR1 Negative_regulation of Gene_expression of ITGB3BP 1 0.05 0.47 0.38
77 INT91656 SLC8A1 Negative_regulation of Positive_regulation of CASP1 1 0.01 0.2 0.38
78 INT185530 Binding of AGT and EDNRA 1 0.00 0.31 0.38
79 INT197591 Esr1 Regulation of Pgr 1 0.04 0 0.38
80 INT149221 Binding of Ryr1 and Trpc3 5 0.40 0 0.37
81 INT91652 Negative_regulation of SLC8A1 Negative_regulation of CASP1 1 0.02 0.21 0.37
82 INT117359 Binding of Esr1 and Wbc1 1 0.00 1.38 0.37
83 INT80444 Binding of EDNRA and SPR 1 0.05 0.1 0.36
84 INT291555 Binding of ESR1 and Dlat 1 0.01 0.6 0.35
85 INT353689 Binding of Slc8a1 and Ca2 1 0.15 0.58 0.33
86 INT291554 Binding of ESR1 and St8sia2 1 0.01 0.49 0.33
87 INT153896 Snx27 Regulation of KCNJ3 1 0.04 0.17 0.33
88 INT303030 Binding of Ednra and MCPH1 1 0.00 1.02 0.32
89 INT119603 H2-Ab1 Regulation of EDNRA 1 0.00 0.07 0.32
90 INT119602 EDNRA Regulation of H2-Ab1 1 0.00 0.07 0.32
91 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
92 INT303005 Binding of Ednra and Pah 1 0.06 1.02 0.32
93 INT296459 Binding of Dlg1 and Gria1 1 0.02 0.23 0.31
94 INT69365 Binding of EDNRA and Pnoc 1 0.00 0 0.31
95 INT284137 EDNRB Regulation of EDNRA 1 0.07 0.09 0.3
96 INT309156 Esr1 Regulation of Gene_expression of Dlat 1 0.05 1.06 0.3
97 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
98 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3
99 INT117588 Binding of C5AR1 and EDNRA 1 0.40 0.38 0.3
100 INT222301 Binding of ERBB2 and ESR1 5 0.36 5.07 0.29
101 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
102 INT158734 Esr1 Regulation of Esrrb 1 0.00 0.28 0.29
103 INT215645 Binding of Adora1 and Kcnj5 1 0.00 0.08 0.29
104 INT158733 Esr1 Regulation of Plxna3 1 0.03 0.27 0.29
105 INT178102 EDNRA Positive_regulation of Localization of TIMP1 1 0.06 0.97 0.28
106 INT178088 EDNRA Positive_regulation of Transcription of TIMP1 1 0.06 0.97 0.28
107 INT77753 Abnormal Regulation of CACNA1S 1 0.00 0.78 0.28
108 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28
109 INT199978 ESR1 Regulation of ITGB3BP 1 0.03 0.39 0.28
110 INT71904 Binding of ESR1 and PGR 6 0.34 3.79 0.27
111 INT323152 Binding of DBT and ESR1 2 0.02 1.29 0.27
112 INT190998 ADCYAP1 Positive_regulation of Scn2a1 1 0.07 0.45 0.27
113 INT239226 Binding of Edn1 and Ednra 2 0.06 1.59 0.26
114 INT346195 AMELX Negative_regulation of ESR1 1 0.02 0.36 0.26
115 INT124117 Apcs Negative_regulation of Ednra 1 0.09 0 0.26
116 INT279828 Binding of Scn1a and Scn9a 1 0.39 1.64 0.26
117 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26
118 INT219918 Positive_regulation of EDNRA Positive_regulation of Trpv1 1 0.13 0 0.26
119 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26
120 INT274942 Binding of Dlg1 and Ephb6 1 0.05 0 0.25
121 INT186783 Binding of ESR1 and NRIP1 1 0.31 0.79 0.25
122 INT199970 CYP19A1 Positive_regulation of Gene_expression of ESR1 1 0.06 0.72 0.25
123 INT182346 Binding of Cd3e and Esr1 1 0.06 1.26 0.25
124 INT182349 Binding of Ms4a1 and Esr1 1 0.04 1.26 0.25
125 INT199971 IL6 Positive_regulation of ESR1 1 0.08 0.84 0.24
126 INT36875 Binding of EDNRA and SYNCRIP 1 0.01 0 0.24
127 INT214412 CASQ1 Regulation of JUND 1 0.02 0.46 0.24
128 INT309160 Binding of Esr1 and Edc4 1 0.03 0.34 0.24
129 INT63203 INS Positive_regulation of ESR1 1 0.09 0.3 0.23
130 INT328896 Scn2a1 Regulation of hb 1 0.02 0.27 0.23
131 INT262151 Vdr Regulation of Cyp24a1 1 0.24 0.24 0.23
132 INT63198 POMC Positive_regulation of ESR1 1 0.14 0.3 0.23
133 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22
134 INT353691 Slc8a1 Positive_regulation of Ca2 1 0.18 0.45 0.22
135 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
136 INT284139 EDNRB Positive_regulation of Gene_expression of EDNRA 1 0.12 0.45 0.22
137 INT36876 EDNRA Regulation of Negative_regulation of PRB1 1 0.00 0 0.21
138 INT283373 Pcbd1 Regulation of RYR1 1 0.00 1.45 0.21
139 INT354519 Cacna1c Regulation of Mri1 1 0.00 1.15 0.21
140 INT106825 Ednra Negative_regulation of Igf1 1 0.07 0.07 0.2
141 INT308645 Binding of Esr1 and Itpr3 1 0.00 0 0.2
142 INT178086 Binding of EDNRA and PTK2 1 0.07 0.82 0.2
143 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19
144 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
145 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
146 INT353697 Binding of NA and Slc8a1 1 0.01 0.42 0.19
147 INT192219 CASP3 Regulation of ESR1 1 0.03 1.19 0.19
148 INT197618 Binding of Esr1 and Ppt1 1 0.01 0 0.18
149 INT173932 Binding of Esr1 and Il6 1 0.03 0.11 0.18
150 INT60778 Edn1 Positive_regulation of EDNRA 1 0.00 0 0.18
151 INT190985 Vip Regulation of Scn2a1 1 0.09 0 0.18
152 INT334769 Ednra Positive_regulation of Car2 1 0.02 0.49 0.18
153 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17
154 INT256985 Binding of Dlg1 and Cd81 1 0.39 0.2 0.17
155 INT19042 ESR1 Positive_regulation of GGT5 1 0.03 0.6 0.17
156 INT19045 ESR1 Positive_regulation of Salpa1 1 0.02 0.6 0.17
157 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16
158 INT153895 Regulation of Snx27 Regulation of KCNJ3 1 0.04 0.08 0.16
159 INT278828 Positive_regulation of Binding of EDN1 and EDNRA 1 0.06 0.51 0.15
160 INT309154 Esr1 Positive_regulation of Gsdmc 1 0.01 0.44 0.15
161 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15
162 INT309155 Negative_regulation of Esr1 Positive_regulation of Gsdmc 1 0.01 0.45 0.15
163 INT279829 Scn1a Regulation of Gene_expression of Scn9a 1 0.42 1.52 0.15
164 INT181752 Binding of CPOX and ESR1 1 0.02 0.89 0.14
165 INT291644 Binding of DST and ESR1 1 0.05 0.84 0.14
166 INT115205 Positive_regulation of Ednra Positive_regulation of Localization of Avp 1 0.36 0 0.14
167 INT334770 Ednra Positive_regulation of Pla2g4a 1 0.00 0.24 0.14
168 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14
169 INT334765 Ednra Positive_regulation of Positive_regulation of Car2 1 0.02 0.24 0.14
170 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
171 INT219920 EDNRA Positive_regulation of Trpv1 1 0.14 0 0.13
172 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13
173 INT334759 Ednra Regulation of Gabrg1 1 0.01 0 0.13
174 INT267973 Binding of CHKB and ESR1 1 0.02 1.67 0.13
175 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13
176 INT330156 Scn2a1 Regulation of Transcription of Pcsk1n 1 0.13 0 0.13
177 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13
178 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
179 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12
180 INT333765 Positive_regulation of Vdr Regulation of Gene_expression of Ccr6 1 0.21 0.48 0.12
181 INT341827 Binding of ESR1 and TNC 1 0.14 0.63 0.11
182 INT351427 Binding of PIK3C3 and RYR1 1 0.00 0 0.11
183 INT341775 DBT Regulation of Binding of ESR1 1 0.02 0.1 0.11
184 INT252779 Binding of ESR1 and RAF1 1 0.01 2.03 0.11
185 INT149219 Binding of Ryr1 and Trpc1 1 0.35 0 0.11
186 INT334761 Binding of Ednra and Gopc 1 0.03 0 0.11
187 INT220114 Tnfrsf1a Positive_regulation of Esr1 1 0.14 1.14 0.1
188 INT293627 GHRL Positive_regulation of EDNRA 1 0.00 0.96 0.1
189 INT214014 Binding of Dysf and Nav1 1 0.00 0.5 0.1
190 INT190982 Avp Positive_regulation of Scn2a1 1 0.17 0.17 0.1
191 INT237819 Binding of Esr1 and soc 1 0.04 0 0.1
192 INT279407 Binding of ESR1 and IGKV2-19 1 0.02 0.4 0.1
193 INT225740 RYR1 Positive_regulation of Binding of Entpd1 1 0.08 0.08 0.1
194 INT125000 Binding of Esr1 and Tas2r108 1 0.04 0.33 0.1
195 INT139476 Edn1 Positive_regulation of Ednra 1 0.00 1.07 0.1
196 INT237812 Esr1 Positive_regulation of Positive_regulation of soc 1 0.05 0.6 0.1
197 INT201747 Itpr3 Positive_regulation of Localization of Esr1 2 0.03 1.19 0.09
198 INT166723 Binding of Vdr and Rxrb 1 0.11 0.31 0.09
199 INT308662 Binding of Esr1 and Fdft1 1 0.00 0.05 0.09
200 INT166724 Binding of Vdr and Rxra 1 0.28 0.32 0.09

Single Events

The table below shows the top 100 pain related interactions that have been reported for T-tubule. They are ordered first by their pain relevance and then by number of times they were reported in T-tubule. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34
2 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64
3 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81
4 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69
5 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63
6 INT37296 Binding of Esr1 117 0.43 62.51 27.33
7 INT20462 Binding of ESR1 210 0.44 102.7 26.34
8 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67
9 INT20003 Gene_expression of Scn2a1 125 0.71 8.78 23.94
10 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52
11 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72
12 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52
13 INT6728 Gene_expression of Ednra 43 0.65 13.41 17.38
14 INT17237 Regulation of Esr1 74 0.43 49.09 17.25
15 INT49768 Positive_regulation of Kcnj5 58 0.41 11.89 16.02
16 INT92354 Localization of ESR1 77 0.75 33.04 15.51
17 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15
18 INT2038 Localization of Esr1 104 0.79 40.12 13.27
19 INT57882 Negative_regulation of Kcnj5 33 0.35 13.06 12.27
20 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18
21 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79
22 INT28843 Positive_regulation of Scn2a1 31 0.68 5.35 10.7
23 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7
24 INT128906 Gene_expression of Kcnj5 35 0.43 7.48 10.33
25 INT75919 Gene_expression of Slc8a1 23 0.63 16.44 9.84
26 INT6727 Positive_regulation of Ednra 27 0.64 18.75 8.71
27 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
28 INT30382 Negative_regulation of Ednra 21 0.42 12.06 8.19
29 INT15687 Regulation of ESR1 91 0.60 40.42 7.95
30 INT77804 Regulation of Ednra 9 0.39 2.71 7.94
31 INT54978 Binding of EDNRA 36 0.41 14.97 7.86
32 INT67170 Gene_expression of Ednra 22 0.65 9.35 7.57
33 INT18393 Negative_regulation of Ryr1 15 0.43 3.63 7.57
34 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4
35 INT167049 Binding of Ednra 3 0.07 3.47 6.84
36 INT17674 Localization of Scn2a1 32 0.61 1.73 6.79
37 INT110987 Transcription of ESR1 45 0.71 24.16 6.72
38 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29
39 INT101008 Gene_expression of Scn5a 5 0.75 26.93 6.06
40 INT90188 Positive_regulation of KCNJ3 7 0.67 0 5.84
41 INT20280 Positive_regulation of Esr1 32 0.69 18.37 5.69
42 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53
43 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51
44 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49
45 INT103518 Negative_regulation of SCN2A 17 0.57 8.4 5.4
46 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36
47 INT59555 Binding of RYR1 39 0.42 8.65 4.92
48 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84
49 INT92858 Negative_regulation of Ednra 6 0.57 1.25 4.81
50 INT246315 Localization of Ednra 22 0.15 2.73 4.64
51 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57
52 INT21953 Binding of Ednra 12 0.33 4.72 4.56
53 INT56159 Regulation of Scn2a1 17 0.51 3.23 4.27
54 INT143337 Binding of Aqp4 30 0.40 23.73 4.24
55 INT160023 Regulation of Aqp4 9 0.45 8.41 4.19
56 INT117205 Transcription of Esr1 23 0.65 9.4 4.14
57 INT52608 Gene_expression of Kcnj3 16 0.78 0.42 4.03
58 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79
59 INT190722 Positive_regulation of Gene_expression of Scn2a1 15 0.36 0.5 3.78
60 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77
61 INT225965 Localization of Aqp4 26 0.81 18.85 3.75
62 INT218955 Protein_catabolism of ESR1 9 0.92 3.95 3.74
63 INT20461 Binding of Esr1 34 0.48 9.58 3.66
64 INT28844 Negative_regulation of Scn2a1 15 0.37 3.84 3.65
65 INT130836 Transcription of Aqp4 6 0.72 5.93 3.52
66 INT268032 Regulation of Kcnj5 23 0.27 3.66 3.51
67 INT18396 Positive_regulation of Ryr1 10 0.58 2.45 3.38
68 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36
69 INT115203 Negative_regulation of Positive_regulation of Ednra 5 0.33 1.27 3.32
70 INT98068 Gene_expression of SCN2A 19 0.75 14.42 3.31
71 INT130835 Positive_regulation of Transcription of Aqp4 3 0.68 4.5 3.28
72 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26
73 INT18394 Regulation of Ryr1 6 0.60 0.28 3.26
74 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22
75 INT73918 Transcription of Esr1 21 0.66 8.74 3.12
76 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11
77 INT49971 Regulation of Ednra 10 0.35 2.4 3.06
78 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
79 INT155349 Positive_regulation of Gene_expression of Aqp4 8 0.70 6.26 2.94
80 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92
81 INT93058 Positive_regulation of Gene_expression of Ednra 8 0.28 4.11 2.88
82 INT31541 Regulation of Esr1 15 0.54 4.12 2.82
83 INT89834 Positive_regulation of SCN2A 8 0.49 1.89 2.77
84 INT160633 Gene_expression of Vdr 21 0.77 10.01 2.73
85 INT76836 Positive_regulation of Ednra 6 0.55 2.65 2.72
86 INT174727 Positive_regulation of Positive_regulation of ESR1 14 0.44 6.3 2.7
87 INT118518 Positive_regulation of Slc8a1 7 0.56 5.31 2.59
88 INT104563 Localization of Aqp4 10 0.73 7.82 2.54
89 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47
90 INT225966 Regulation of Gene_expression of Aqp4 18 0.62 20.39 2.3
91 INT80733 Binding of Scn2a1 11 0.30 1.09 2.3
92 INT19286 Negative_regulation of Cacna1c 11 0.46 5.12 2.22
93 INT168959 Gene_expression of CAV3 5 0.65 0.7 2.2
94 INT74486 Positive_regulation of SCN1A 4 0.67 1 2.2
95 INT105824 Regulation of Casq1 4 0.07 2.66 2.1
96 INT156677 Regulation of Gene_expression of Ednra 4 0.15 0.25 2.05
97 INT155344 Phosphorylation of Aqp4 1 0.82 4 2.05
98 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04
99 INT157927 Gene_expression of Scn1a 5 0.64 6.55 2.02
100 INT140171 Binding of Aqp4 7 0.36 11.63 1.98
101 INT112368 Positive_regulation of Cacna1c 8 0.46 2.94 1.97
102 INT34860 Negative_regulation of Gene_expression of Scn2a1 8 0.30 0.97 1.94
103 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92
104 INT160634 Gene_expression of Slc8a1 2 0.64 2.12 1.92
105 INT218959 Negative_regulation of Protein_catabolism of ESR1 3 0.37 0.97 1.9
106 INT25835 Binding of Slc8a1 3 0.36 0.47 1.79
107 INT168757 Binding of Kcnj5 3 0.16 0.53 1.77
108 INT168964 Negative_regulation of Gene_expression of CAV3 1 0.47 0 1.68
109 INT96971 Positive_regulation of Gene_expression of Esr1 6 0.46 2.27 1.67
110 INT53134 Localization of Kcnj3 2 0.79 0 1.67
111 INT11713 Localization of RYR1 22 0.76 10.42 1.64
112 INT73355 Negative_regulation of Slc8a1 5 0.47 2.35 1.61
113 INT222089 Positive_regulation of Localization of Esr1 19 0.49 8.73 1.58
114 INT123076 Gene_expression of Cacna1c 7 0.37 1.91 1.56
115 INT133885 Binding of SCN2A 7 0.47 1.27 1.54
116 INT72021 Localization of Ednra 7 0.58 3.13 1.53
117 INT164480 Negative_regulation of Gene_expression of Aqp4 14 0.58 10.84 1.52
118 INT79001 Positive_regulation of Localization of Scn2a1 3 0.36 0.22 1.48
119 INT23938 Positive_regulation of Gene_expression of EDNRA 8 0.45 9.82 1.47
120 INT153599 Gene_expression of SCN1A 8 0.75 7.01 1.47
121 INT15048 Regulation of Cacna1c 4 0.29 3.26 1.47
122 INT65452 Negative_regulation of Cacna1c 8 0.09 0.8 1.44
123 INT129488 Regulation of Gene_expression of EDNRA 5 0.51 3.39 1.44
124 INT155345 Negative_regulation of Phosphorylation of Aqp4 1 0.43 2.86 1.37
125 INT152964 Regulation of Gene_expression of Aqp4 3 0.56 4.18 1.34
126 INT143451 Negative_regulation of Gene_expression of Scn5a 2 0.43 4.63 1.34
127 INT90186 Positive_regulation of Positive_regulation of KCNJ3 1 0.49 0 1.34
128 INT55305 Regulation of RYR1 14 0.45 5.27 1.33
129 INT77752 Binding of Cacna1c 3 0.22 0.22 1.31
130 INT8511 Localization of Esr1 6 0.80 3.27 1.26
131 INT92848 Gene_expression of Scn5a 3 0.73 0.23 1.25
132 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23
133 INT90190 Gene_expression of KCNJ3 3 0.75 0 1.23
134 INT168095 Positive_regulation of Transcription of Cav3 1 0.47 0.91 1.2
135 INT824 Negative_regulation of Negative_regulation of ESR1 3 0.42 1.53 1.18
136 INT228648 Binding of Scn1a 1 0.27 1.95 1.15
137 INT112214 Gene_expression of Vdr 4 0.33 3.59 1.11
138 INT141116 Transcription of Scn2a1 9 0.45 1.1 1.1
139 INT163159 Gene_expression of Casq1 2 0.58 1.21 1.09
140 INT66452 Positive_regulation of Cacna1c 6 0.19 2.56 1.08
141 INT146085 Negative_regulation of Positive_regulation of SCN2A 1 0.41 0.26 1.07
142 INT81945 Negative_regulation of Binding of Esr1 3 0.32 0.55 1.06
143 INT168957 Positive_regulation of CAV3 1 0.40 0 1.06
144 INT168960 Binding of CAV3 1 0.30 0 1.05
145 INT209218 Gene_expression of Dlg1 3 0.54 0.42 1.03
146 INT190964 Regulation of Gene_expression of Scn2a1 7 0.29 1.29 1.02
147 INT202378 Transcription of Aqp4 5 0.65 1.7 1.02
148 INT80500 Localization of Slc8a1 4 0.61 1.37 1.02
149 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98
150 INT78935 Localization of Cacna1c 3 0.48 1.25 0.97
151 INT72024 Localization of EDNRA 11 0.57 8.22 0.96
152 INT154468 Negative_regulation of Transcription of ESR1 3 0.29 1.14 0.96
153 INT76835 Negative_regulation of Gene_expression of Ednra 2 0.10 0.89 0.96
154 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95
155 INT90187 Negative_regulation of KCNJ3 2 0.57 0.17 0.95
156 INT341484 Negative_regulation of SCN1A 1 0.53 1.27 0.94
157 INT149903 Localization of Cav3 3 0.80 1.1 0.93
158 INT236576 Positive_regulation of Binding of Esr1 3 0.41 2.39 0.92
159 INT154465 Negative_regulation of Transcription of Esr1 1 0.05 0 0.92
160 INT116831 Binding of Ryr1 11 0.47 0.12 0.9
161 INT128755 Protein_catabolism of Esr1 10 0.57 4.61 0.9
162 INT128907 Regulation of Gene_expression of Kcnj5 4 0.19 0.59 0.89
163 INT143450 Negative_regulation of Scn5a 3 0.43 2.71 0.88
164 INT178133 Negative_regulation of Positive_regulation of EDNRA 2 0.35 2.18 0.88
165 INT38446 Localization of Ryr1 3 0.64 0.28 0.86
166 INT73914 Negative_regulation of Transcription of Esr1 3 0.39 0.75 0.84
167 INT174728 Positive_regulation of Transcription of ESR1 10 0.47 3.3 0.83
168 INT125092 Negative_regulation of Binding of ESR1 8 0.42 4.15 0.82
169 INT93576 Negative_regulation of Dysf 3 0.54 1.79 0.82
170 INT33818 Positive_regulation of Negative_regulation of Esr1 3 0.40 0.98 0.82
171 INT91666 Localization of SLC8A1 2 0.02 0.25 0.82
172 INT149905 Negative_regulation of Cav3 2 0.43 0.98 0.82
173 INT90185 Negative_regulation of Positive_regulation of KCNJ3 1 0.42 0 0.81
174 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
175 INT93577 Positive_regulation of Dysf 2 0.46 0.75 0.77
176 INT186579 Positive_regulation of Gene_expression of Ednra 5 0.07 0.89 0.76
177 INT235953 Regulation of Binding of Aqp4 4 0.45 4.4 0.76
178 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75
179 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73
180 INT92082 Regulation of Binding of ESR1 5 0.45 2.41 0.73
181 INT123075 Positive_regulation of Gene_expression of Cacna1c 1 0.05 0.73 0.73
182 INT239494 Regulation of Localization of Esr1 4 0.19 1.15 0.72
183 INT262107 Binding of Vdr 9 0.48 6.56 0.71
184 INT272206 Gene_expression of CAPN3 4 0.77 3.83 0.7
185 INT73917 Regulation of Transcription of Esr1 4 0.25 1.5 0.7
186 INT313697 Phosphorylation of Ednra 1 0.18 0 0.7
187 INT68589 Gene_expression of Cacna1c 14 0.58 6.36 0.69
188 INT202374 Negative_regulation of Transcription of Aqp4 2 0.37 1.34 0.69
189 INT70104 Positive_regulation of CACNA1S 6 0.47 5.92 0.68
190 INT52607 Positive_regulation of Gene_expression of Kcnj3 2 0.40 0.17 0.68
191 INT262060 Positive_regulation of Vdr 8 0.58 2.84 0.67
192 INT64775 Binding of Kcnj3 1 0.32 0 0.65
193 INT191177 Regulation of Localization of ESR1 7 0.42 2.04 0.64
194 INT190961 Negative_regulation of Positive_regulation of Scn2a1 2 0.27 0.15 0.64
195 INT9836 Negative_regulation of Negative_regulation of Esr1 3 0.29 0.95 0.63
196 INT126563 Negative_regulation of Positive_regulation of Kcnj5 2 0.19 0.63 0.63
197 INT126355 Negative_regulation of Camk2d 1 0.49 0.23 0.63
198 INT101748 Localization of Kcnj5 3 0.20 0.73 0.62
199 INT168963 Negative_regulation of Binding of CAV3 1 0.30 0 0.62
200 INT168962 Positive_regulation of Localization of CAV3 1 0.40 0 0.62
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