GO:0030316

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Name osteoclast differentiation
Categary Process
Go Slim No
Go Link GO:0030316
Unique Molecular Interactions 895
Total Molecular Interactions 1419
Total Single Events 11297
Pain Genes Associated 32

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for osteoclast differentiation. They are ordered first by their pain relevance and then by number of times they were reported for osteoclast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT139706 Tnf Positive_regulation of Ltp 1 0.03 2.61 4.63
2 INT146412 Tnf Positive_regulation of Gene_expression of Trpv1 2 0.66 5.22 3.22
3 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11
4 INT140024 Tnf Positive_regulation of Gene_expression of Il1b 2 0.49 2.75 2.61
5 INT152501 Binding of Tnf and Tnfrsf1a 4 0.31 3 2.58
6 INT151826 Tnf Positive_regulation of TNF 1 0.04 3.38 2.51
7 INT61733 Tlr4 Positive_regulation of Gene_expression of Tnf 3 0.26 1.99 2.36
8 INT139705 Negative_regulation of Tnf Positive_regulation of Ltp 1 0.03 1.19 2.3
9 INT94491 Il1b Positive_regulation of Gene_expression of Tnf 1 0.25 3.81 2.19
10 INT94504 Il6 Positive_regulation of Gene_expression of Tnf 1 0.30 3.8 2.19
11 INT140032 Tnf Positive_regulation of Gene_expression of Ifng 2 0.43 2.23 2
12 INT140026 Il1b Positive_regulation of Gene_expression of Tnf 2 0.49 2.23 2
13 INT129212 RYBP Positive_regulation of Tnf 2 0.03 1.9 1.95
14 INT137207 Tnf Positive_regulation of Nfkb1 3 0.23 2.69 1.71
15 INT119413 SEMA6A Positive_regulation of TNFRSF11A 1 0.10 2.48 1.7
16 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
17 INT208991 Binding of CALM1 and Ca2 10 0.06 1.34 1.55
18 INT208980 Binding of Ca2 and Trpv1 4 0.32 0.67 1.55
19 INT158775 Regulation of Tnf Regulation of Ephb1 1 0.18 0.09 1.52
20 INT158777 Tnf Regulation of Ephb1 1 0.18 0.09 1.51
21 INT140029 Ifng Positive_regulation of Gene_expression of Tnf 1 0.43 1.69 1.5
22 INT3573 Tf Negative_regulation of Localization of Gh1 1 0.36 0 1.49
23 INT161513 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Tnf 1 0.33 0.27 1.35
24 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33
25 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
26 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
27 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
28 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21
29 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21
30 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
31 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
32 INT139704 Tnf Positive_regulation of Mapk14 1 0.22 0.73 1.1
33 INT94495 Tnf Positive_regulation of Gene_expression of Il6 1 0.30 1.9 1.09
34 INT151825 Tnf Positive_regulation of Mapk14 1 0.22 1.72 1.09
35 INT94500 Tnf Positive_regulation of Gene_expression of Il1b 1 0.25 1.9 1.09
36 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
37 INT152502 Tnf Negative_regulation of Binding of Tnfrsf1a 1 0.37 0.6 1.08
38 INT120312 Ghrh Regulation of Tnf 1 0.26 0.95 1.05
39 INT120314 Ghrh Regulation of Positive_regulation of Tnf 1 0.43 0.95 1.05
40 INT152504 Binding of CR1 and Tnf 1 0.00 0.49 1.04
41 INT81545 Tnf Positive_regulation of Gtf3a 2 0.03 1.41 1.02
42 INT353690 Binding of Grin2b and Ca2 1 0.14 1.17 1.01
43 INT129216 Negative_regulation of RYBP Positive_regulation of Tnf 1 0.01 1.24 0.98
44 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
45 INT154254 Tnf Positive_regulation of Il6 1 0.36 0.94 0.97
46 INT129211 RYBP Positive_regulation of Gene_expression of Tnf 1 0.01 1.04 0.94
47 INT155259 RUNX1 Negative_regulation of Tnf 1 0.00 1.48 0.93
48 INT165280 Tnf Positive_regulation of Gene_expression of Nos2 1 0.24 1.02 0.91
49 INT256646 Tnf Positive_regulation of Positive_regulation of Nfkb1 1 0.22 1.83 0.9
50 INT120147 Tlr4 Positive_regulation of Tnf 3 0.39 2.14 0.89
51 INT142278 Slc8a1 Regulation of Tnf 1 0.14 0.07 0.89
52 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88
53 INT134311 Tnf Positive_regulation of Protein_catabolism of Nfkbia 1 0.18 0.57 0.88
54 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
55 INT116556 Olr1627 Negative_regulation of Regulation of Tnf 1 0.01 1.52 0.87
56 INT187225 Vip Negative_regulation of Gene_expression of Tnfrsf11a 1 0.27 1.92 0.87
57 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86
58 INT152868 Tnf Regulation of Gene_expression of Trpv1 1 0.27 0.25 0.86
59 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84
60 INT146919 Tnf Positive_regulation of Gene_expression of Ccl2 1 0.16 1.44 0.84
61 INT149626 Il1b Regulation of Gene_expression of Tnf 1 0.41 0.83 0.83
62 INT102201 Tnf Regulation of Il1b 3 0.39 2.57 0.82
63 INT270217 Binding of C2 and Ca2 1 0.03 1.63 0.81
64 INT251172 Trpv1 Regulation of Gene_expression of Ca2 1 0.13 0.7 0.81
65 INT126555 Binding of Ighg1 and Tnf 1 0.35 2.2 0.8
66 INT132894 CHUK Regulation of Gene_expression of Nos2 1 0.00 0.21 0.79
67 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
68 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78
69 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77
70 INT152869 Tnf Positive_regulation of Gene_expression of Trpv1 1 0.46 0.48 0.77
71 INT136795 Spp1 Positive_regulation of Chuk 1 0.11 1.54 0.77
72 INT209883 TNF Positive_regulation of Gene_expression of TNFRSF11A 1 0.20 1.83 0.77
73 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77
74 INT209882 IL4 Positive_regulation of Gene_expression of TNFRSF11A 1 0.11 1.82 0.76
75 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75
76 INT107702 DCSTAMP Positive_regulation of Gene_expression of CPOX 1 0.04 0.32 0.75
77 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
78 INT354455 Il11 Negative_regulation of Gene_expression of Tnf 1 0.31 1.21 0.74
79 INT96301 Olr1742 Negative_regulation of Gene_expression of Tnf 1 0.14 0 0.74
80 INT150992 Sfpq Negative_regulation of Gene_expression of Tnf 1 0.03 0.69 0.72
81 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71
82 INT208978 Ca2 Positive_regulation of Trpv1 1 0.22 0.29 0.71
83 INT159963 Tnf Positive_regulation of Localization of Il6 1 0.12 2.32 0.71
84 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7
85 INT103134 DCSTAMP Positive_regulation of NFKB1 2 0.07 1.43 0.7
86 INT772 Tf Positive_regulation of Positive_regulation of Oprl1 1 0.11 0 0.7
87 INT778 Tf Positive_regulation of Gh1 1 0.14 0 0.7
88 INT782 Tf Positive_regulation of Prl 1 0.43 0 0.7
89 INT251169 Clu Regulation of Ca2 1 0.03 0.66 0.7
90 INT83625 Tnf Positive_regulation of Gene_expression of Cd59 1 0.15 1.08 0.69
91 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
92 INT187220 Il11 Positive_regulation of Gene_expression of Tnfsf11 1 0.13 0.86 0.69
93 INT314199 Mapk14 Regulation of Tnf 1 0.26 0.71 0.67
94 INT148139 Phosphorylation of Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.46 0.98 0.66
95 INT148138 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.64 0.98 0.66
96 INT120144 Negative_regulation of Tlr4 Positive_regulation of Tnf 1 0.18 0.91 0.66
97 INT120146 seb Positive_regulation of Gene_expression of Tnf 1 0.40 0.86 0.66
98 INT120145 seb Positive_regulation of Tnf 1 0.40 0.85 0.65
99 INT251165 Trpv1 Positive_regulation of Gene_expression of Ca2 1 0.15 0.54 0.65
100 INT132689 Tnf Regulation of Dnajc13 1 0.01 1.27 0.65
101 INT165047 Mapk14 Positive_regulation of Gene_expression of Tnf 1 0.73 0.8 0.63
102 INT165048 Trib3 Positive_regulation of Gene_expression of Tnf 1 0.08 0.8 0.63
103 INT148137 Tnf Positive_regulation of Positive_regulation of Mapk14 1 0.46 1 0.63
104 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62
105 INT9163 Tnf Regulation of Gene_expression of Glul 1 0.12 1.99 0.62
106 INT61826 Tnf Negative_regulation of Il1b 1 0.39 0.89 0.62
107 INT50816 Penk Positive_regulation of Localization of Ca2 1 0.32 0 0.62
108 INT158362 Tnf Positive_regulation of Steap4 1 0.55 1.6 0.61
109 INT314197 Mapk14 Positive_regulation of Positive_regulation of Tnf 1 0.48 1.16 0.61
110 INT70254 Binding of Htr1a and Ca2 1 0.31 0.5 0.6
111 INT40901 Trf Regulation of Localization of POMC 1 0.07 0.56 0.6
112 INT96241 Il13 Negative_regulation of Tnf 1 0.08 0.6 0.59
113 INT202160 Binding of ARSD and CSF1R 1 0.16 1.69 0.59
114 INT56451 Ifng Positive_regulation of Tnf 1 0.00 1.92 0.59
115 INT61827 Tnf Regulation of Lta 1 0.40 1.5 0.58
116 INT94506 Tnf Positive_regulation of Gene_expression of Avp 1 0.31 0.98 0.57
117 INT94507 Tnf Positive_regulation of Gene_expression of AVP 1 0.39 0.98 0.57
118 INT8402 Tnf Regulation of Gene_expression of Vip 1 0.02 0.38 0.56
119 INT278694 TNF Positive_regulation of MAPK14 1 0.03 0.79 0.56
120 INT8400 Tnf Regulation of Gene_expression of Nts 1 0.00 0.38 0.56
121 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56
122 INT146112 Binding of Il1b and Tnf 1 0.32 1.19 0.56
123 INT94499 Tnf Positive_regulation of Gene_expression of Crh 1 0.27 0.97 0.56
124 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55
125 INT131316 Tnf Positive_regulation of Mpo 1 0.29 0.65 0.55
126 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55
127 INT176343 CHI3L1 Positive_regulation of Localization of CSF1 1 0.23 1.86 0.55
128 INT120143 Tlr4 Negative_regulation of Gene_expression of Tnf 1 0.18 0.76 0.55
129 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54
130 INT254279 Il13 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
131 INT202157 Binding of CSF1R and SLC6A4 1 0.08 0.9 0.54
132 INT254280 Il4 Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.79 0.54
133 INT176342 CSF1 Positive_regulation of Localization of CSF2 1 0.26 1.84 0.54
134 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54
135 INT208984 Binding of Ca2 and Fig4 1 0.02 0 0.54
136 INT216918 Binding of Ca2 and Abat 1 0.01 0.45 0.53
137 INT118138 Binding of Ca2 and Mgat4a 1 0.01 0 0.53
138 INT8397 Tnf Regulation of Nts 1 0.00 0.38 0.53
139 INT8398 Tnf Regulation of Vip 1 0.01 0.38 0.53
140 INT171906 MAPK1 Positive_regulation of Gene_expression of MAPK14 1 0.08 1.55 0.52
141 INT297479 Ryr2 Positive_regulation of Ca2 1 0.22 0 0.52
142 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51
143 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51
144 INT187227 Vip Negative_regulation of Gene_expression of Tnfsf11 1 0.35 1.23 0.51
145 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51
146 INT23090 Tnf Positive_regulation of Localization of Prl 1 0.18 0.15 0.5
147 INT23091 Tnf Positive_regulation of Localization of Ggh 1 0.05 0.15 0.5
148 INT330796 P2ry1 Positive_regulation of Ca2 1 0.05 0.06 0.5
149 INT23092 Tnf Positive_regulation of Prl 1 0.08 0.15 0.5
150 INT93740 Ddc Positive_regulation of Tnf 1 0.00 1.45 0.5
151 INT23089 Tnf Positive_regulation of Ggh 1 0.04 0.15 0.5
152 INT285344 Il10 Negative_regulation of Gene_expression of Tnf 1 0.15 1.91 0.49
153 INT161227 Binding of Ngfr and Tnf 1 0.06 0.41 0.49
154 INT155621 Tnf Regulation of Transcription of Il1b 1 0.51 0.77 0.49
155 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49
156 INT187796 Binding of Tnf and Il1 1 0.09 1.85 0.48
157 INT67440 Pdyn Regulation of Gene_expression of Tnf 1 0.23 0.19 0.48
158 INT162890 Negative_regulation of Binding of LEP and Tnf 1 0.03 0.49 0.48
159 INT162889 Binding of LEP and Tnf 1 0.03 0.49 0.48
160 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
161 INT187795 Positive_regulation of Binding of Tnf and Il1 1 0.13 1.87 0.48
162 INT250077 Positive_regulation of Ltp Positive_regulation of Localization of Ca2 1 0.10 0 0.48
163 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48
164 INT137416 Binding of SDC1 and Tnf 1 0.00 1.19 0.47
165 INT314200 Positive_regulation of Binding of Nos2 and Tnf 1 0.42 0.34 0.46
166 INT314201 Binding of Nos2 and Tnf 1 0.31 0.33 0.46
167 INT161652 Gsr Regulation of Gene_expression of Tnf 1 0.17 0.98 0.46
168 INT259208 Ca2 Positive_regulation of Phosphorylation of Creb1 1 0.04 0 0.45
169 INT96245 Negative_regulation of Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
170 INT96246 Tnf Positive_regulation of KNG1 1 0.01 0.59 0.45
171 INT148635 Abat Negative_regulation of Gene_expression of Tnf 1 0.10 0.53 0.44
172 INT86380 Adra2a Regulation of Gene_expression of Tnf 1 0.15 0.79 0.44
173 INT254460 Binding of Calm2 and Ca2 5 0.03 0.48 0.43
174 INT103132 Positive_regulation of DCSTAMP Positive_regulation of JUN 1 0.03 0.73 0.43
175 INT126019 Binding of Ltbr and Tnf 1 0.18 1.61 0.43
176 INT126020 Binding of fc and Tnf 1 0.22 1.61 0.43
177 INT107694 Tnf Positive_regulation of Gene_expression of Cxcl1 1 0.60 0.63 0.43
178 INT142273 KITLG Positive_regulation of Gene_expression of Tnf 1 0.07 0.9 0.43
179 INT278964 MAPK14 Negative_regulation of Localization of EPHB2 1 0.15 0.47 0.43
180 INT51475 Binding of Il6 and Tnf 1 0.15 0.61 0.43
181 INT126018 Binding of Lifr and Tnf 1 0.06 1.61 0.43
182 INT103128 Positive_regulation of DCSTAMP Positive_regulation of NFKB1 1 0.07 0.73 0.43
183 INT103129 DCSTAMP Positive_regulation of JUN 1 0.03 0.72 0.43
184 INT346130 Il17a Positive_regulation of Gene_expression of TNFSF11 1 0.08 0.61 0.41
185 INT147977 Tnf Positive_regulation of Il4 1 0.01 1.12 0.41
186 INT165568 Tnf Regulation of Gene_expression of Il1b 1 0.41 1.26 0.41
187 INT100594 DCSTAMP Positive_regulation of Gene_expression of IL6 1 0.03 0.24 0.41
188 INT354984 Binding of Cacna1a and Tnf 1 0.01 0.83 0.4
189 INT230500 Il1 Positive_regulation of Gene_expression of Tnf 1 0.07 1.83 0.4
190 INT134761 Ghrl Regulation of Localization of Tnf 1 0.20 0.76 0.4
191 INT154756 Tnf Positive_regulation of Nfkb1 1 0.31 0.78 0.4
192 INT168458 Sult1a1 Negative_regulation of Tnf 1 0.09 1 0.4
193 INT172125 Binding of Tnfrsf11b and Tnfrsf11a 2 0.17 2.12 0.39
194 INT165565 Tnf Regulation of Gene_expression of Sdf2l1 1 0.26 1.15 0.39
195 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
196 INT103130 DCSTAMP Positive_regulation of Gene_expression of IL8 1 0.09 0.65 0.39
197 INT288700 Binding of Cp and Tfrc 1 0.40 0 0.39
198 INT228761 Tnf Positive_regulation of Gene_expression of Ccl17 1 0.20 0.66 0.39
199 INT165566 Tnf Regulation of Gene_expression of Il6 1 0.32 1.15 0.39
200 INT15028 NA Positive_regulation of Localization of Ca2 1 0.04 0 0.39

Single Events

The table below shows the top 100 pain related interactions that have been reported for osteoclast differentiation. They are ordered first by their pain relevance and then by number of times they were reported in osteoclast differentiation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68
2 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58
3 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1
4 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64
5 INT4822 Localization of Ca2 417 0.80 99.57 96.45
6 INT10166 Localization of Tnf 237 0.81 153.95 88.64
7 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71
8 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71
9 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54
10 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85
11 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05
12 INT13286 Gene_expression of Ca2 317 0.67 71.58 65.01
13 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47
14 INT1032 Regulation of Ca2 202 0.52 54.91 53.03
15 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16
16 INT55670 Negative_regulation of Gene_expression of Tnf 83 0.59 57.16 46.33
17 INT5307 Regulation of Tnf 87 0.62 78.71 43.4
18 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66
19 INT35406 Localization of Tnf 94 0.81 64.63 31.65
20 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59
21 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73
22 INT86534 Positive_regulation of MAPK14 81 0.62 57.81 23.62
23 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71
24 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33
25 INT171924 Gene_expression of MAPK14 60 0.65 54.38 21.68
26 INT53575 Regulation of Gene_expression of Tnf 46 0.62 34.35 20.63
27 INT53574 Regulation of Tnf 45 0.62 40.68 19.71
28 INT66751 Negative_regulation of Localization of Tnf 48 0.59 26 19.36
29 INT66755 Transcription of Tnf 45 0.72 37.1 19.11
30 INT14546 Positive_regulation of Localization of Ca2 93 0.67 31.09 18.72
31 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75
32 INT49986 Transcription of Tnf 25 0.72 18.3 16.22
33 INT10173 Binding of Tnf 45 0.48 35.6 14.32
34 INT113625 Positive_regulation of Gene_expression of Ca2 47 0.50 9.82 14.07
35 INT64048 Positive_regulation of Positive_regulation of Tnf 32 0.70 21.24 13.74
36 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94
37 INT19799 Binding of Ca2 71 0.48 13.69 12.92
38 INT10433 Positive_regulation of Junb 35 0.70 6.55 12.42
39 INT9483 Gene_expression of Junb 34 0.78 3.24 12.08
40 INT60434 Negative_regulation of Positive_regulation of Tnf 20 0.46 10.01 10.64
41 INT93533 Positive_regulation of Tnfsf11 53 0.50 36.93 10.53
42 INT110178 Phosphorylation of MAPK14 40 0.68 19.38 10.37
43 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34
44 INT17283 Positive_regulation of CSF1 37 0.59 24.16 10.01
45 INT33094 Regulation of Localization of Ca2 28 0.38 8.65 9.96
46 INT23094 Positive_regulation of Positive_regulation of Ca2 29 0.49 6.8 9.35
47 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78
48 INT53573 Negative_regulation of Localization of Tnf 19 0.59 11.57 8.54
49 INT15805 Gene_expression of TFRC 35 0.75 17.44 8.52
50 INT171962 Gene_expression of Tnfrsf11a 40 0.72 31.1 7.84
51 INT68299 Binding of Tnf 17 0.39 12.55 7.49
52 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45
53 INT9478 Positive_regulation of Gene_expression of Junb 19 0.70 2.34 7.41
54 INT104207 Positive_regulation of Gene_expression of Tnfsf11 43 0.69 25.8 7.35
55 INT66752 Positive_regulation of Transcription of Tnf 15 0.68 10.86 7.26
56 INT19366 Negative_regulation of Localization of Ca2 33 0.50 6.51 6.61
57 INT136555 Negative_regulation of Tnfsf11 31 0.55 22.23 6.23
58 INT113700 Positive_regulation of Chuk 30 0.41 21.17 5.69
59 INT6487 Positive_regulation of Positive_regulation of Tnf 21 0.56 16.06 5.64
60 INT152433 Binding of CSF1R 6 0.33 10.97 5.54
61 INT149739 Regulation of Gene_expression of Ca2 25 0.38 7.22 5.53
62 INT58145 Positive_regulation of Localization of Tnf 20 0.67 13.33 5.44
63 INT92054 Positive_regulation of Transcription of Tnf 8 0.50 4.93 5.05
64 INT6983 Negative_regulation of Positive_regulation of Ca2 18 0.41 4.29 5.03
65 INT129856 Positive_regulation of TNFRSF11A 26 0.68 16.21 4.75
66 INT12194 Gene_expression of Trf 38 0.69 18.1 4.56
67 INT11565 Gene_expression of Tf 24 0.68 5.89 4.36
68 INT117920 Regulation of MAPK14 14 0.38 8.75 4.31
69 INT117921 Positive_regulation of Positive_regulation of MAPK14 9 0.44 9.93 4.18
70 INT93016 Binding of TNFRSF11A 29 0.47 19.67 4.17
71 INT134646 Gene_expression of Tnfsf11 19 0.69 14.77 4.16
72 INT15239 Regulation of Junb 13 0.62 1.14 4.1
73 INT66754 Negative_regulation of Transcription of Tnf 11 0.43 8.43 3.93
74 INT23088 Phosphorylation of Tnf 15 0.79 9.85 3.82
75 INT152254 Gene_expression of CSF1R 16 0.75 12.93 3.81
76 INT129746 Positive_regulation of Gene_expression of Tfrc 4 0.18 2.15 3.74
77 INT46621 Positive_regulation of Gene_expression of CSF1 17 0.47 10.53 3.59
78 INT15801 Positive_regulation of TFRC 11 0.33 6.35 3.3
79 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22
80 INT68846 Gene_expression of Tfrc 22 0.32 10.1 3.06
81 INT171959 Binding of Tnfrsf11a 15 0.34 11.03 3.02
82 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99
83 INT174958 Negative_regulation of Chuk 21 0.25 8.73 2.96
84 INT177993 Localization of CSF1R 4 0.73 7.49 2.94
85 INT46620 Positive_regulation of Positive_regulation of CSF1 1 0.12 2.9 2.94
86 INT173179 Binding of MAPK14 13 0.29 4.51 2.92
87 INT15549 Regulation of Positive_regulation of Ca2 11 0.38 2.55 2.92
88 INT46650 Localization of Trf 13 0.61 4.4 2.91
89 INT64186 Positive_regulation of Gene_expression of TNFRSF11A 13 0.68 7.19 2.9
90 INT101567 Gene_expression of Ctnnb1 7 0.64 10.11 2.89
91 INT93531 Negative_regulation of Gene_expression of Tnfsf11 15 0.43 7.74 2.84
92 INT95049 Negative_regulation of Regulation of Tnf 4 0.42 1.64 2.84
93 INT2042 Phosphorylation of Ca2 21 0.55 1.54 2.81
94 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78
95 INT178002 Positive_regulation of CSF1R 2 0.37 6.52 2.74
96 INT70253 Negative_regulation of Gene_expression of Ca2 29 0.49 16.31 2.69
97 INT17033 Positive_regulation of Trf 21 0.62 11.76 2.68
98 INT222845 Gene_expression of Chuk 27 0.52 25.15 2.67
99 INT75736 Regulation of Localization of Tnf 6 0.62 4.61 2.67
100 INT51753 Negative_regulation of Tfrc 7 0.41 3.47 2.62
101 INT81989 Positive_regulation of Tnfsf11 11 0.54 7.57 2.4
102 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39
103 INT93532 Regulation of Tnfsf11 14 0.42 10.75 2.39
104 INT110179 Negative_regulation of Phosphorylation of MAPK14 11 0.36 5.25 2.38
105 INT21726 Gene_expression of Tfrc 10 0.74 7.38 2.36
106 INT66804 Negative_regulation of Negative_regulation of Tnf 4 0.56 2.79 2.26
107 INT100603 Gene_expression of DCSTAMP 7 0.22 3.05 2.25
108 INT132893 Binding of CHUK 1 0.00 0.63 2.25
109 INT72743 Positive_regulation of Negative_regulation of Ca2 4 0.49 1.41 2.11
110 INT173647 Positive_regulation of Gene_expression of MAPK14 15 0.39 7.54 2.05
111 INT82543 Negative_regulation of Gene_expression of TFRC 4 0.57 1.27 2.03
112 INT132892 Positive_regulation of CHUK 3 0.08 1.62 2.01
113 INT83332 Regulation of Gene_expression of TFRC 5 0.22 3.03 1.99
114 INT81641 Gene_expression of Ctnnb1 23 0.72 14.93 1.97
115 INT122649 Positive_regulation of Regulation of Tnf 2 0.49 2.78 1.96
116 INT83329 Regulation of Gene_expression of Tf 4 0.16 1.83 1.93
117 INT97019 Negative_regulation of Binding of TNFRSF11A 4 0.17 1.8 1.89
118 INT134890 Localization of TNFRSF11A 1 0.79 3.75 1.86
119 INT36499 Negative_regulation of Tf 6 0.38 3.02 1.85
120 INT130866 Positive_regulation of Gene_expression of TNFSF11 25 0.69 7.11 1.82
121 INT77801 Negative_regulation of Binding of Tnf 5 0.42 3.93 1.77
122 INT134889 Negative_regulation of TNFRSF11A 9 0.42 12.65 1.76
123 INT171964 Positive_regulation of Gene_expression of Tnfrsf11a 5 0.37 4.11 1.73
124 INT23609 Negative_regulation of Acp5 5 0.33 1.69 1.65
125 INT159957 Positive_regulation of Phosphorylation of Tnf 3 0.49 2.63 1.65
126 INT173173 Regulation of Positive_regulation of MAPK14 6 0.38 2.59 1.64
127 INT123990 Positive_regulation of Ctnnb1 8 0.43 2.85 1.63
128 INT182643 Binding of TNFSF11 15 0.35 13.12 1.61
129 INT99391 Localization of Ctnnb1 7 0.80 5.84 1.61
130 INT132890 Positive_regulation of Binding of CHUK 1 0.00 0.44 1.6
131 INT132891 Gene_expression of CHUK 1 0.01 0.47 1.58
132 INT127724 Localization of CSF1 12 0.73 9.35 1.56
133 INT19798 Positive_regulation of Binding of Ca2 2 0.41 1.37 1.54
134 INT182297 Positive_regulation of Phosphorylation of MAPK14 7 0.42 3.36 1.53
135 INT61967 Positive_regulation of Negative_regulation of Tnf 3 0.50 2.46 1.49
136 INT59795 Regulation of Tfrc 5 0.43 4.43 1.48
137 INT119936 Transcription of Ca2 13 0.59 1.71 1.47
138 INT162057 Negative_regulation of TNFSF11 14 0.58 9.78 1.46
139 INT173654 Localization of MAPK14 12 0.62 3.16 1.43
140 INT15798 Positive_regulation of Gene_expression of TFRC 9 0.46 4.99 1.42
141 INT83659 Negative_regulation of Binding of Tnf 3 0.37 1.57 1.42
142 INT105551 Transcription of Tnfsf11 6 0.69 4.21 1.38
143 INT143716 Phosphorylation of Chuk 16 0.41 5.25 1.35
144 INT16239 Negative_regulation of Trf 9 0.32 4.06 1.35
145 INT95668 Positive_regulation of Tnfrsf11a 12 0.47 10.14 1.34
146 INT217438 Binding of Chuk 24 0.25 7.29 1.29
147 INT36500 Negative_regulation of Gene_expression of Tf 4 0.38 1.22 1.29
148 INT135181 Regulation of Gene_expression of TNFSF11 5 0.61 6.98 1.27
149 INT135186 Negative_regulation of Gene_expression of TNFSF11 10 0.58 2.69 1.25
150 INT23610 Gene_expression of Acp5 4 0.51 0.96 1.23
151 INT153757 Positive_regulation of Mitf 10 0.46 8.38 1.22
152 INT112823 Negative_regulation of Positive_regulation of MAPK14 5 0.36 1.49 1.22
153 INT202161 Negative_regulation of CSF1R 3 0.31 3.36 1.22
154 INT99389 Negative_regulation of Ctnnb1 8 0.45 3.97 1.21
155 INT298979 Gene_expression of Traf6 5 0.31 1.75 1.21
156 INT6996 Positive_regulation of Tfrc 6 0.70 2.22 1.2
157 INT36443 Regulation of Trf 4 0.61 1.65 1.18
158 INT769 Regulation of Tf 3 0.30 1 1.18
159 INT105552 Positive_regulation of Transcription of Tnfsf11 3 0.31 2.94 1.17
160 INT9477 Regulation of Gene_expression of Junb 5 0.45 0.88 1.15
161 INT62496 Binding of CSF1 6 0.36 4.55 1.14
162 INT224429 Regulation of TNFSF11 8 0.61 4.35 1.13
163 INT49536 Regulation of Regulation of Ca2 6 0.38 3.89 1.13
164 INT110394 Regulation of CSF1R 3 0.38 2.49 1.12
165 INT58174 Gene_expression of Junb 9 0.78 1.38 1.09
166 INT209895 Transcription of TNFRSF11A 4 0.52 2.56 1.09
167 INT129587 Protein_catabolism of Tnf 2 0.86 1.41 1.08
168 INT168276 Negative_regulation of Phosphorylation of Tnf 1 0.19 1.3 1.08
169 INT82540 Negative_regulation of TFRC 3 0.41 0.77 1.07
170 INT101570 Positive_regulation of Gene_expression of Ctnnb1 1 0.58 5.7 1.07
171 INT153769 Negative_regulation of Tnfrsf11a 4 0.39 2.13 1.05
172 INT135027 Regulation of Positive_regulation of Tnf 3 0.38 2.84 1.05
173 INT210586 Negative_regulation of Positive_regulation of Tnfsf11 3 0.41 1.4 1.02
174 INT184479 Regulation of Tfrc 3 0.09 3.97 1.01
175 INT132847 Negative_regulation of Localization of Tnfsf11 1 0.32 0.16 1.01
176 INT3568 Localization of Tf 4 0.62 1.27 1
177 INT61030 Negative_regulation of Positive_regulation of Junb 2 0.41 0.93 0.95
178 INT95669 Regulation of TNFRSF11A 7 0.56 10.01 0.94
179 INT15304 Regulation of Acp5 2 0.44 0.2 0.94
180 INT171963 Positive_regulation of Positive_regulation of Tnfsf11 3 0.42 2.44 0.93
181 INT194875 Regulation of Negative_regulation of MAPK14 1 0.04 2.39 0.91
182 INT52232 Positive_regulation of Positive_regulation of Junb 4 0.47 0.45 0.88
183 INT101566 Negative_regulation of Gene_expression of Ctnnb1 1 0.35 2.28 0.88
184 INT134307 Negative_regulation of Protein_catabolism of Tnf 1 0.41 0.57 0.88
185 INT115822 Regulation of Transcription of Tnf 3 0.35 1.96 0.87
186 INT134310 Positive_regulation of Protein_catabolism of Tnf 1 0.49 0.57 0.87
187 INT107712 Positive_regulation of Gene_expression of DCSTAMP 2 0.09 1.56 0.86
188 INT89368 Positive_regulation of Tf 7 0.34 3.62 0.83
189 INT21727 Positive_regulation of Gene_expression of Tfrc 3 0.19 1.68 0.82
190 INT174194 Negative_regulation of Gene_expression of CSF1 3 0.33 2.05 0.8
191 INT103135 Positive_regulation of DCSTAMP 2 0.09 0.86 0.8
192 INT187218 Negative_regulation of Gene_expression of Tnfrsf11a 1 0.31 1.65 0.8
193 INT294998 Positive_regulation of Gene_expression of Tnfsf11 5 0.62 2.98 0.79
194 INT136690 Regulation of Negative_regulation of Tnf 5 0.45 3.58 0.78
195 INT102199 Regulation of Transcription of Tnf 2 0.45 2.25 0.78
196 INT76015 Localization of DCSTAMP 3 0.14 1.04 0.77
197 INT72628 Regulation of CSF1 7 0.25 1.95 0.75
198 INT287841 Positive_regulation of Phosphorylation of Ca2 2 0.18 0.58 0.75
199 INT237158 Negative_regulation of Negative_regulation of Tnf 2 0.13 1.37 0.74
200 INT197722 Regulation of TFRC 4 0.14 1.2 0.72
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