GO:0030317

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Name sperm motility
Categary Process
Go Slim No
Go Link GO:0030317
Unique Molecular Interactions 131
Total Molecular Interactions 190
Total Single Events 1170
Pain Genes Associated 16

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for sperm motility. They are ordered first by their pain relevance and then by number of times they were reported for sperm motility. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT322411 Hist1h1t Positive_regulation of Positive_regulation of OPRM1 1 0.00 1.25 3.63
2 INT168758 Hist1h1t Positive_regulation of Phosphorylation of Akt1 2 0.02 0.44 2.79
3 INT322410 Hist1h1t Positive_regulation of Phosphorylation of OPRM1 1 0.00 0.08 2.31
4 INT174450 Positive_regulation of Binding of Cxcr3 and Smcp 1 0.18 2.83 1.49
5 INT350862 Hist1h1t Regulation of Kcnj5 1 0.02 1.35 1.22
6 INT131173 Chrna7 Positive_regulation of Localization of Abat 1 0.10 0 1.01
7 INT214408 ATP1A4 Regulation of DNAH8 1 0.04 1.01 0.94
8 INT214409 ATP1A4 Regulation of CAPN1 1 0.01 1.01 0.93
9 INT23681 Negative_regulation of Binding of Stx3 and Chrna7 1 0.00 0 0.75
10 INT23680 Binding of Stx3 and Chrna7 1 0.00 0 0.75
11 INT174454 Binding of Cxcr3 and Smcp 1 0.14 1.41 0.74
12 INT43662 Negative_regulation of Binding of Chrna7 and Rac1 1 0.01 0 0.73
13 INT43663 Binding of Chrna7 and Rac2 1 0.01 0 0.72
14 INT43661 Binding of Chrna7 and Rac1 1 0.01 0 0.72
15 INT174455 Smcp Positive_regulation of Gene_expression of Cxcr3 1 0.17 1.31 0.71
16 INT214410 Binding of ATP1A4 and CACNA1A 1 0.26 0.95 0.7
17 INT174453 Smcp Positive_regulation of Cxcr3 1 0.17 1.29 0.64
18 INT350859 Hist1h1t Regulation of Gene_expression of Kcnj5 1 0.02 0.37 0.59
19 INT350861 Hist1h1t Positive_regulation of Gene_expression of Kcnj5 1 0.02 0.35 0.56
20 INT23679 Chrna7 Regulation of Binding of Stx3 1 0.00 0 0.56
21 INT350860 Hist1h1t Positive_regulation of Kcnj5 1 0.02 0.54 0.5
22 INT83111 LIAS Negative_regulation of Binding of Chrna7 1 0.02 0 0.45
23 INT148930 Rac1 Regulation of Chrna7 1 0.13 0.6 0.44
24 INT322396 Hist1h1t Positive_regulation of Akt1 1 0.01 0 0.42
25 INT322394 Hist1h1t Positive_regulation of Pik3cb 1 0.01 0 0.42
26 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38
27 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 0.00 1.25 0.37
28 INT46788 Chrna7 Positive_regulation of G6pd 1 0.50 0 0.33
29 INT280190 Cbs Regulation of Gene_expression of Hist1h1t 1 0.04 0.58 0.32
30 INT59682 Hps6 Positive_regulation of Binding of Chrna7 1 0.02 0 0.29
31 INT349537 Smcp Positive_regulation of Tnfsf10 1 0.38 3.48 0.28
32 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28
33 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26
34 INT59683 Binding of Chrna7 and Evi2a 1 0.03 0 0.25
35 INT143972 Chrna7 Negative_regulation of Gene_expression of Trpv1 1 0.01 0.18 0.24
36 INT299155 Smcp Negative_regulation of Spp1 1 0.00 0.7 0.22
37 INT299156 Smcp Negative_regulation of Tnc 1 0.05 0.7 0.22
38 INT299154 Smcp Negative_regulation of Lgals3 1 0.04 0.69 0.22
39 INT143974 Chrna7 Positive_regulation of Vti1b 1 0.17 0.16 0.2
40 INT349538 Smcp Positive_regulation of Positive_regulation of Casp9 1 0.04 0.68 0.18
41 INT47426 Chrna7 Positive_regulation of Localization of Ldha 1 0.05 0 0.18
42 INT47427 Chrna7 Positive_regulation of Ldha 1 0.05 0 0.18
43 INT349539 Smcp Positive_regulation of Positive_regulation of Casp8 1 0.04 0.68 0.18
44 INT101725 Binding of ITGA4 and Chrna7 1 0.00 0 0.16
45 INT340111 Chrna7 Regulation of CYSLTR1 1 0.00 0.25 0.15
46 INT278265 Binding of Fgf2 and Smcp 1 0.03 0.26 0.14
47 INT290194 Binding of PLTP and Hdl1 1 0.07 7.3 0.13
48 INT308585 Binding of APOB and PLA2G7 1 0.07 0.69 0.09
49 INT171709 Rac1 Negative_regulation of Localization of Chrna7 1 0.04 0.75 0.08
50 INT290182 Binding of CETP and PLTP 1 0.26 3.31 0.05
51 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04
52 INT332411 Akt1 Positive_regulation of Phosphorylation of Met 1 0.31 0.05 0.04
53 INT293899 UPF1 Positive_regulation of Gene_expression of APOB 1 0.01 0 0.04
54 INT352062 Binding of SV2A and Chrna7 1 0.00 0.7 0.04
55 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04
56 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04
57 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04
58 INT332410 Mapk1 Positive_regulation of Phosphorylation of Met 1 0.32 0.05 0.04
59 INT310041 Gtf3a Positive_regulation of Met 1 0.00 0.15 0.03
60 INT194481 Binding of Apoe and Apob 1 0.07 0.51 0.03
61 INT310040 Hgf Positive_regulation of Met 1 0.06 0.15 0.03
62 INT194486 Binding of SNRNP70 and Apob 1 0.00 0.64 0.03
63 INT197466 Dpcd Positive_regulation of Sostdc1 1 0.00 0 0
64 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0
65 INT353795 Binding of Cd320 and Apob 1 0.08 0.82 0
66 INT171598 Binding of APOB and Lipg 1 0.01 0.63 0
67 INT353798 Binding of Hdl1 and Apob 1 0.01 0.82 0
68 INT278264 Gene_expression of Ntf3 Positive_regulation of Smcp 1 0.02 0.32 0
69 INT310043 Binding of Met and Slc30a4 1 0.05 0.35 0
70 INT349530 Tnfsf10 Negative_regulation of Smcp 1 0.28 0.88 0
71 INT298849 Binding of APOB and MCC 1 0.00 0.38 0
72 INT349535 Binding of Smcp and Tnfsf10 1 0.36 6.79 0
73 INT353802 Binding of APOE and Apob 1 0.05 0.83 0
74 INT210417 APOB Negative_regulation of CYP2D6 1 0.01 0 0
75 INT298856 Binding of APOB and MTG1 1 0.00 0.38 0
76 INT197467 Binding of Dpcd and Memor1 1 0.00 0.12 0
77 INT286444 PCSK9 Positive_regulation of Apob 1 0.02 0.49 0
78 INT277047 Binding of APOB and LDLR 1 0.25 0.82 0
79 INT299440 Gtf3a Regulation of Rhox5 1 0.01 0.15 0
80 INT332405 Met Regulation of Positive_regulation of Mapk1 1 0.17 0.18 0
81 INT170212 Gene_expression of PLTP Positive_regulation of HSD11B1 1 0.12 3.01 0
82 INT279694 Hc Negative_regulation of Catsper1 1 0.05 0 0
83 INT170214 PLTP Positive_regulation of HSD11B1 1 0.11 1.34 0
84 INT197469 Binding of Dpcd and Hbtq 1 0.00 0 0
85 INT304944 Positive_regulation of Binding of Tnp1 and Ca2 1 0.04 0.33 0
86 INT344723 Niacr1 Positive_regulation of Binding of APOB 1 0.31 1.05 0
87 INT353796 Binding of Ldlr and Apob 1 0.06 0.82 0
88 INT247438 Binding of APOB and SACM1L 1 0.28 2 0
89 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0
90 INT197468 Dpcd Positive_regulation of Hbtq 1 0.00 0 0
91 INT349532 Positive_regulation of Binding of Smcp and Tnfsf10 1 0.35 2.16 0
92 INT239319 Pltp Regulation of Apoa1 1 0.22 0.65 0
93 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0
94 INT352794 Binding of APOB and FGF21 1 0.01 1.98 0
95 INT304945 Binding of Tnp1 and Ca2 1 0.03 0.97 0
96 INT298861 Binding of APOB and RAB7A 1 0.00 0.32 0
97 INT85010 Apo Regulation of Apob 1 0.00 0.14 0
98 INT235169 Gene_expression of Dnaja1 Negative_regulation of Binding of Atxn1 1 0.09 0.47 0
99 INT168759 Hist1h1t Positive_regulation of Positive_regulation of Oprm1 1 0.02 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for sperm motility. They are ordered first by their pain relevance and then by number of times they were reported in sperm motility. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT23330 Binding of Chrna7 79 0.48 10.06 35.5
2 INT23675 Negative_regulation of Binding of Chrna7 18 0.37 0.5 10.74
3 INT23676 Gene_expression of Chrna7 47 0.75 23.66 9.51
4 INT147366 Gene_expression of Hist1h1t 15 0.44 9.84 6.67
5 INT539 Negative_regulation of Chrna7 14 0.42 4.59 6.42
6 INT174423 Gene_expression of Smcp 39 0.48 29.45 6.06
7 INT75682 Regulation of Chrna7 14 0.45 10.24 5.25
8 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95
9 INT4649 Positive_regulation of Chrna7 17 0.50 5.48 3.92
10 INT149507 Positive_regulation of Hist1h1t 4 0.26 2.71 2.33
11 INT174446 Positive_regulation of Smcp 7 0.33 5.47 2.24
12 INT24196 Positive_regulation of Binding of Chrna7 8 0.45 0.79 2.13
13 INT174415 Transcription of Smcp 1 0.23 3.52 1.9
14 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86
15 INT47425 Localization of Chrna7 11 0.81 6.7 1.86
16 INT280198 Regulation of Hist1h1t 2 0.21 1.28 1.69
17 INT322389 Phosphorylation of Hist1h1t 1 0.03 0 1.67
18 INT169387 Regulation of Gene_expression of Chrna7 4 0.36 2.19 1.63
19 INT167847 Positive_regulation of Gene_expression of Chrna7 7 0.49 3.02 1.57
20 INT9466 Binding of APOB 27 0.41 19.36 1.56
21 INT174434 Localization of Smcp 6 0.53 2.45 1.46
22 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39
23 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36
24 INT103960 Gene_expression of ATP1A4 4 0.73 3.05 1.34
25 INT179217 Positive_regulation of ATP1A4 2 0.11 0.91 1.34
26 INT20238 Regulation of APOB 9 0.61 11.52 1.26
27 INT103527 Positive_regulation of Smcp 5 0.41 2.25 1.26
28 INT151822 Gene_expression of Catsper1 2 0.62 2.62 1.24
29 INT24197 Regulation of Binding of Chrna7 2 0.11 0 1.14
30 INT280196 Positive_regulation of Gene_expression of Hist1h1t 1 0.07 1.62 1.02
31 INT174424 Binding of Smcp 9 0.25 2.68 0.94
32 INT214417 Regulation of ATP1A4 1 0.38 1.01 0.93
33 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9
34 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88
35 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85
36 INT278254 Positive_regulation of Localization of Smcp 1 0.24 0 0.85
37 INT10828 Regulation of Apob 7 0.39 7.55 0.83
38 INT21246 Negative_regulation of ATP1A4 3 0.10 3.3 0.79
39 INT51739 Negative_regulation of Apob 9 0.42 4.21 0.78
40 INT147195 Negative_regulation of Smcp 4 0.38 3.53 0.65
41 INT280195 Regulation of Gene_expression of Hist1h1t 1 0.04 1.09 0.63
42 INT179362 Gene_expression of Smcp 5 0.54 4.5 0.52
43 INT228243 Negative_regulation of Met 3 0.41 4.78 0.51
44 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48
45 INT116427 Negative_regulation of Smcp 10 0.31 2.72 0.41
46 INT278253 Positive_regulation of Gene_expression of Smcp 3 0.29 1.24 0.39
47 INT128155 Regulation of Smcp 3 0.23 0.89 0.39
48 INT179223 Regulation of Gene_expression of ATP1A4 1 0.02 1.23 0.37
49 INT169388 Transcription of Chrna7 2 0.69 0.27 0.36
50 INT169386 Regulation of Transcription of Chrna7 1 0.45 0.05 0.36
51 INT339386 Negative_regulation of Gene_expression of Apob 3 0.43 1.91 0.34
52 INT174440 Negative_regulation of Positive_regulation of Smcp 1 0.14 0.65 0.32
53 INT174436 Positive_regulation of Negative_regulation of Smcp 1 0.15 0.65 0.32
54 INT83352 Positive_regulation of Negative_regulation of APOB 1 0.01 0.69 0.31
55 INT211553 Gene_expression of Pltp 2 0.48 0.96 0.3
56 INT179215 Positive_regulation of Gene_expression of ATP1A4 1 0.06 0.24 0.28
57 INT280192 Negative_regulation of Gene_expression of Hist1h1t 1 0.04 0.54 0.27
58 INT193847 Gene_expression of Met 22 0.65 6.6 0.24
59 INT170229 Gene_expression of PLTP 9 0.77 21.32 0.24
60 INT48473 Binding of Smcp 5 0.31 5.14 0.24
61 INT179220 Negative_regulation of Gene_expression of ATP1A4 1 0.04 1.11 0.24
62 INT334903 Positive_regulation of Localization of Chrna7 2 0.04 0.83 0.23
63 INT194472 Positive_regulation of Gene_expression of Apob 2 0.15 1.71 0.22
64 INT279684 Positive_regulation of Catsper1 1 0.40 0.21 0.22
65 INT5683 Negative_regulation of Dpcd 1 0.10 0.52 0.2
66 INT332367 Regulation of Met 1 0.58 0.7 0.2
67 INT310012 Positive_regulation of Met 9 0.65 3.57 0.19
68 INT538 Protein_catabolism of Chrna7 2 0.57 1.01 0.19
69 INT203836 Negative_regulation of Negative_regulation of Apob 1 0.18 0.45 0.19
70 INT149506 Negative_regulation of Hist1h1t 2 0.30 0.83 0.18
71 INT62274 Negative_regulation of Gene_expression of APOB 4 0.32 5.9 0.16
72 INT277049 Regulation of Binding of APOB 1 0.27 0.91 0.16
73 INT226831 Regulation of Gene_expression of Met 2 0.37 0.44 0.15
74 INT189972 Positive_regulation of PLTP 3 0.60 8.99 0.13
75 INT203827 Localization of Apob 3 0.32 1.81 0.13
76 INT240040 Protein_catabolism of Apob 1 0.01 1.79 0.13
77 INT240041 Negative_regulation of Protein_catabolism of Apob 1 0.01 1.8 0.13
78 INT194469 Positive_regulation of Apob 3 0.15 2.29 0.12
79 INT1796 Phosphorylation of Chrna7 1 0.82 0 0.12
80 INT43207 Regulation of Positive_regulation of Chrna7 1 0.01 0 0.11
81 INT332353 Phosphorylation of Met 1 0.77 0.5 0.1
82 INT235511 Transcription of Apob 1 0.13 0.45 0.1
83 INT278252 Regulation of Smcp 2 0.29 1.58 0.09
84 INT170234 Positive_regulation of Gene_expression of PLTP 4 0.69 10.56 0.08
85 INT213136 Binding of Apob 2 0.03 2.76 0.07
86 INT213138 Negative_regulation of Binding of Apob 1 0.03 0.86 0.07
87 INT213137 Positive_regulation of Binding of Apob 1 0.04 0.87 0.07
88 INT179763 Localization of Apob 6 0.66 4.72 0.06
89 INT239409 Transcription of APOB 3 0.65 1.86 0.06
90 INT235517 Positive_regulation of Positive_regulation of Apob 1 0.10 0.58 0.06
91 INT92979 Regulation of Rhox5 1 0.08 0.64 0.06
92 INT183389 Regulation of Apob 4 0.01 5.17 0.05
93 INT255451 Positive_regulation of Positive_regulation of APOB 2 0.37 1.91 0.05
94 INT211556 Localization of Pltp 1 0.56 0.15 0.05
95 INT197461 Positive_regulation of Dpcd 1 0.01 0.05 0.05
96 INT239411 Localization of APOB 10 0.76 5.71 0.04
97 INT226827 Binding of Met 3 0.10 1.24 0.04
98 INT240615 Binding of Apob 2 0.07 0.85 0.04
99 INT310005 Positive_regulation of Positive_regulation of Met 1 0.14 0.62 0.04
100 INT279690 Negative_regulation of Catsper1 1 0.39 0 0.04
101 INT332371 Positive_regulation of Phosphorylation of Met 1 0.47 0.05 0.04
102 INT332376 Negative_regulation of Positive_regulation of Met 1 0.55 0 0.04
103 INT282020 Gene_expression of Rhox5 1 0.02 0 0.04
104 INT246579 Negative_regulation of Localization of APOB 1 0.05 0.23 0.04
105 INT212051 Negative_regulation of Gene_expression of PLTP 4 0.43 1.05 0.03
106 INT310008 Negative_regulation of Gene_expression of Met 2 0.41 0.48 0.03
107 INT325018 Regulation of Gene_expression of Apob 2 0.16 1.59 0.03
108 INT290186 Negative_regulation of Positive_regulation of PLTP 1 0.43 0.68 0.03
109 INT290191 Transcription of PLTP 1 0.60 1.09 0.03
110 INT290184 Binding of PLTP 1 0.48 4.53 0.03
111 INT290185 Positive_regulation of Positive_regulation of PLTP 1 0.46 0.61 0.03
112 INT290188 Regulation of PLTP 1 0.45 0.52 0.03
113 INT252743 Protein_catabolism of APOB 1 0.01 1.68 0.03
114 INT252758 Positive_regulation of Protein_catabolism of APOB 1 0.01 0.98 0.03
115 INT37798 Positive_regulation of Positive_regulation of Apob 1 0.06 1 0.03
116 INT350856 Localization of Hist1h1t 1 0.34 0.35 0.03
117 INT197462 Gene_expression of Dpcd 1 0.01 0.08 0.03
118 INT170228 Negative_regulation of PLTP 3 0.43 4.67 0
119 INT319365 Regulation of Gene_expression of Smcp 3 0.32 0.53 0
120 INT319367 Negative_regulation of Gene_expression of Smcp 2 0.30 0.71 0
121 INT179761 Negative_regulation of Localization of Apob 2 0.40 2.9 0
122 INT332366 Positive_regulation of Negative_regulation of Met 1 0.44 0.24 0
123 INT235153 Negative_regulation of Gene_expression of Dnaja1 1 0.09 0.47 0
124 INT255450 Positive_regulation of Binding of APOB 1 0.37 2.88 0
125 INT310009 Localization of Met 1 0.20 0.22 0
126 INT310017 Regulation of Negative_regulation of Met 1 0.43 0.68 0
127 INT304943 Negative_regulation of Tnp1 1 0.04 0.42 0
128 INT229627 Negative_regulation of Negative_regulation of APOB 1 0.31 0.26 0
129 INT290192 Localization of PLTP 1 0.75 1.74 0
130 INT235152 Localization of Dnaja1 1 0.17 0.72 0
131 INT296561 Positive_regulation of Dnaja1 1 0.43 1.2 0
132 INT241542 Regulation of Gene_expression of Apob 1 0.00 1.8 0
133 INT304942 Negative_regulation of Positive_regulation of Tnp1 1 0.04 0.42 0
134 INT279691 Localization of Catsper1 1 0.60 0 0
135 INT317658 Positive_regulation of Gene_expression of Apob 1 0.17 1.59 0
136 INT193874 Positive_regulation of Gene_expression of Met 1 0.49 0.48 0
137 INT226830 Transcription of Met 1 0.06 0.05 0
138 INT235143 Gene_expression of Dnaja1 1 0.17 0.47 0
139 INT235131 Positive_regulation of Gene_expression of Dnaja1 1 0.15 0.47 0
140 INT290189 Regulation of Gene_expression of PLTP 1 0.45 0 0
141 INT349527 Phosphorylation of Smcp 1 0.58 1.93 0
142 INT336963 Localization of Smcp 1 0.04 1.61 0
143 INT304941 Positive_regulation of Tnp1 1 0.07 0.73 0
144 INT239410 Regulation of Localization of APOB 1 0.25 0.52 0
145 INT282019 Positive_regulation of Gene_expression of Rhox5 1 0.01 0 0
146 INT306793 Negative_regulation of Positive_regulation of APOB 1 0.27 0.33 0
147 INT279693 Positive_regulation of Gene_expression of Catsper1 1 0.46 0.63 0
148 INT239300 Regulation of Pltp 1 0.26 0.64 0
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