GO:0030330

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Name DNA damage response, signal transduction by p53 class mediator
Categary Process
Go Slim No
Go Link GO:0030330
Unique Molecular Interactions 567
Total Molecular Interactions 712
Total Single Events 5120
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for DNA damage response, signal transduction by p53 class mediator. They are ordered first by their pain relevance and then by number of times they were reported for DNA damage response, signal transduction by p53 class mediator. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT254001 Binding of Cxcr4 and Mif 1 0.52 14.17 7.18
3 INT253988 Binding of Cd74 and Mif 1 0.36 6.57 2.52
4 INT203149 Binding of Mif and Osm 1 0.02 2.93 1.78
5 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
6 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
7 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
8 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
9 INT40636 Mif Negative_regulation of Pomc 1 0.25 0.07 0.9
10 INT253992 Cxcl12 Positive_regulation of Mif 1 0.46 1.31 0.88
11 INT203148 Mif Positive_regulation of Gene_expression of S100a8 1 0.00 1.56 0.87
12 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
13 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
14 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
15 INT40703 Mif Negative_regulation of Negative_regulation of POMC 1 0.24 0.49 0.7
16 INT253994 Cyp3a23/3a1 Positive_regulation of Localization of Mif 1 0.09 0.96 0.69
17 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
18 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
19 INT164990 Mif Positive_regulation of Gene_expression of Grina 1 0.24 0.53 0.6
20 INT195773 Binding of Cd74 and Mif 2 0.25 2.78 0.55
21 INT254197 Mif Regulation of Ptgs2 1 0.02 1.08 0.55
22 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
23 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
24 INT253997 Binding of Cd200r1 and Mif 1 0.03 1.02 0.46
25 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
26 INT275402 Trpv1 Regulation of Gene_expression of NDRG1 1 0.00 1.25 0.39
27 INT32212 POMC Regulation of Gene_expression of Mif 1 0.00 1.01 0.35
28 INT72953 Mif Positive_regulation of Localization of Prl 1 0.42 0 0.34
29 INT353333 Positive_regulation of F2r Positive_regulation of Localization of Mif 1 0.46 0.26 0.32
30 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
31 INT72951 Mif Regulation of Prl 1 0.41 0 0.32
32 INT353334 F2r Positive_regulation of Mif 1 0.68 0 0.32
33 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
34 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
35 INT353335 F2r Regulation of Positive_regulation of Mif 1 0.27 0.11 0.31
36 INT337085 Binding of Cxcr4 and Mif 1 0.21 1.89 0.3
37 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
38 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
39 INT56250 Binding of NBN and NCOR2 1 0.00 0 0.3
40 INT140385 Spp1 Negative_regulation of FOXO3 1 0.04 1.29 0.3
41 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
42 INT353336 F2r Regulation of Localization of Mif 1 0.23 0.24 0.28
43 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
44 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
45 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
46 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
47 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
48 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
49 INT72952 Mif Regulation of Localization of Prl 1 0.28 0 0.27
50 INT254000 Regulation of Binding of Cxcr4 and Mif 1 0.29 0.56 0.27
51 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
52 INT353330 F2r Positive_regulation of Positive_regulation of Mif 1 0.46 0 0.26
53 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
54 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
55 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
56 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
57 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
58 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
59 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
60 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
61 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
62 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
63 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
64 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
65 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
66 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
67 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
68 INT132054 NBN Positive_regulation of NOS1 1 0.00 0.08 0.2
69 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
70 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
71 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19
72 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
73 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
74 INT275400 Casp3 Positive_regulation of NDRG1 1 0.00 1.36 0.18
75 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18
76 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
77 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
78 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
79 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
80 INT176623 Binding of PTGER2 and NDRG1 1 0.00 0.1 0.16
81 INT275374 JUN Positive_regulation of NDRG1 1 0.00 1.35 0.15
82 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
83 INT324874 Positive_regulation of Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
84 INT324860 Tlr2 Positive_regulation of Gene_expression of Mif 1 0.05 0.66 0.15
85 INT275375 Binding of ITIH4 and NDRG1 1 0.00 0.65 0.14
86 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
87 INT275396 Binding of NDRG1 and Htatsf1 1 0.00 0.65 0.14
88 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
89 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
90 INT254002 Binding of Cyp3a23/3a1 and Positive_regulation of Gene_expression of Mif 1 0.08 0.56 0.13
91 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
92 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
93 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
94 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
95 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
96 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
97 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
98 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
99 INT222425 Mif Regulation of Tlr4 1 0.01 0.24 0.09
100 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
101 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
102 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
103 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
104 INT337090 Mif Positive_regulation of Gene_expression of Mapk1 1 0.10 1.11 0.08
105 INT337087 Negative_regulation of Binding of Mif and Cops5 1 0.13 1.64 0.08
106 INT222514 Mif Regulation of Localization of Il6 1 0.04 0.23 0.08
107 INT337088 Binding of Mif and Cops5 1 0.12 1.63 0.08
108 INT337084 Negative_regulation of Binding of Cd74 and Mif 1 0.29 1.64 0.08
109 INT273520 NBN Positive_regulation of CDIPT 1 0.06 0.82 0.08
110 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
111 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
112 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
113 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
114 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
115 INT307223 CYLD Positive_regulation of Localization of BCL3 1 0.12 0.51 0.06
116 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
117 INT300310 Akt1 Regulation of Foxo3 1 0.21 1.5 0.06
118 INT307226 CYLD Negative_regulation of Localization of BCL3 1 0.10 0.45 0.06
119 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
120 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
121 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
122 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
123 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
124 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
125 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
126 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
127 INT353341 F2r Positive_regulation of Negative_regulation of Mif 1 0.49 0 0.05
128 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
129 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
130 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
131 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
132 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
133 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
134 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
135 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
136 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
137 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
138 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
139 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
140 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
141 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
142 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
143 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
144 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
145 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
146 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
147 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
148 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
149 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
150 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
151 INT172716 Binding of BCL3 and NFKB1 1 0.06 0.15 0.03
152 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03
153 INT273519 NBN Negative_regulation of YOD1 1 0.03 0.56 0.03
154 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
155 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
156 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0
157 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
158 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
159 INT304020 AR Regulation of TP53 1 0.24 1.11 0
160 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0
161 INT203901 HIVEP1 Positive_regulation of Gene_expression of TP53 1 0.04 0.86 0
162 INT121545 Mif Negative_regulation of Regulation of Ptgs2 1 0.13 0.15 0
163 INT281609 Foxo3 Positive_regulation of Transcription of Trim63 1 0.29 0 0
164 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0
165 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
166 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
167 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0
168 INT333690 Hr Negative_regulation of Transcription of Trp53 1 0.23 0.51 0
169 INT217776 TP53 Regulation of MITF 1 0.00 1.28 0
170 INT334322 Binding of RB1 and TP53 1 0.34 2 0
171 INT342007 Mta1 Regulation of Trp53 1 0.15 0.15 0
172 INT127731 Binding of A2m and Mif 1 0.19 0 0
173 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
174 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
175 INT333689 Hr Positive_regulation of Protein_catabolism of Trp53 1 0.25 1.71 0
176 INT345489 TP53 Positive_regulation of PMAIP1 1 0.05 0.6 0
177 INT286044 Wwox Positive_regulation of Tp53 1 0.05 0.63 0
178 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
179 INT318222 GADD45A Regulation of FOXO3 1 0.16 0.52 0
180 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0
181 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0
182 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
183 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
184 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0
185 INT333455 ATM Positive_regulation of TP53 1 0.18 0 0
186 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0
187 INT177793 EGR1 Positive_regulation of Negative_regulation of TP53 1 0.18 0.44 0
188 INT284232 Binding of TP53 and HNRNPUL1 1 0.26 0.88 0
189 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0
190 INT306256 MDM2 Negative_regulation of Positive_regulation of TP53 1 0.23 0.44 0
191 INT278186 Binding of TP53 and GOPC 1 0.02 0.85 0
192 INT337708 Naf1 Regulation of Gene_expression of Tp53 1 0.09 0.22 0
193 INT345337 Binding of TP53 and BCC1 1 0.11 1.05 0
194 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0
195 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
196 INT268513 MIR34A Regulation of Gene_expression of TP53 1 0.00 0.9 0
197 INT172604 Binding of EP300 and TP53 1 0.00 0 0
198 INT307222 CYLD Regulation of Negative_regulation of BCL3 1 0.10 0.3 0
199 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0
200 INT318218 SIRT1 Positive_regulation of Binding of FOXO3 1 0.44 0.51 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for DNA damage response, signal transduction by p53 class mediator. They are ordered first by their pain relevance and then by number of times they were reported in DNA damage response, signal transduction by p53 class mediator. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT116737 Localization of Mif 63 0.81 52.97 28.11
3 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28
4 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
5 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
6 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
7 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37
8 INT72949 Binding of Mif 31 0.46 23.12 11.65
9 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
10 INT32210 Gene_expression of Mif 13 0.75 28.48 7.79
11 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
12 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
13 INT517 Regulation of Mif 16 0.62 5.43 6.55
14 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
15 INT516 Negative_regulation of Mif 13 0.59 6.69 6.08
16 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
17 INT60585 Regulation of TP53 59 0.59 54.55 5.21
18 INT106667 Gene_expression of NDRG1 18 0.70 9.96 5.14
19 INT174339 Positive_regulation of Localization of Mif 7 0.61 8.27 4.95
20 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
21 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
22 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
23 INT116738 Positive_regulation of Gene_expression of Mif 14 0.68 10.99 3.8
24 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
25 INT130226 Positive_regulation of Gene_expression of Mif 4 0.58 15.75 3.03
26 INT8103 Binding of TP53 46 0.44 40.2 2.96
27 INT203137 Binding of Mif 6 0.31 9.46 2.71
28 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
29 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
30 INT106668 Positive_regulation of Gene_expression of NDRG1 3 0.10 1.93 2.49
31 INT40748 Negative_regulation of Mif 6 0.56 8.33 2.46
32 INT55952 Transcription of TP53 16 0.61 12.14 2.36
33 INT103304 Positive_regulation of Mif 6 0.48 8.66 2.05
34 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
35 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
36 INT65855 Localization of TP53 18 0.76 17.08 1.89
37 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
38 INT91043 Regulation of NDRG1 7 0.25 2.66 1.65
39 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63
40 INT353326 Negative_regulation of Localization of Mif 1 0.45 1.28 1.59
41 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
42 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
43 INT168682 Localization of NDRG1 3 0.36 0.84 1.45
44 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
45 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
46 INT172953 Binding of Trp53 33 0.37 20.76 1.41
47 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
48 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
49 INT168684 Regulation of Localization of NDRG1 1 0.10 0.61 1.4
50 INT145221 Binding of Tp53 10 0.37 8.59 1.37
51 INT253987 Regulation of Localization of Mif 3 0.43 1.65 1.27
52 INT41418 Regulation of Mif 2 0.40 3.86 1.24
53 INT174156 Localization of Trp53 16 0.72 13.52 1.18
54 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
55 INT121368 Transcription of Mif 5 0.72 2.71 1.15
56 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
57 INT131373 Positive_regulation of NDRG1 9 0.67 4.78 1.11
58 INT102827 Protein_catabolism of Mif 1 0.33 0 1.06
59 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
60 INT281594 Phosphorylation of Foxo3 3 0.67 21.16 0.95
61 INT353328 Regulation of Positive_regulation of Mif 1 0.40 0.89 0.81
62 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
63 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
64 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
65 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
66 INT2108 Localization of Mif 5 0.77 2.7 0.73
67 INT32209 Regulation of Gene_expression of Mif 3 0.59 3.41 0.66
68 INT130229 Regulation of Negative_regulation of Mif 1 0.39 1.36 0.66
69 INT353322 Negative_regulation of Positive_regulation of Mif 1 0.38 0.35 0.66
70 INT44148 Negative_regulation of Gene_expression of Mif 6 0.41 0.95 0.64
71 INT56251 Binding of NBN 4 0.38 3.16 0.62
72 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
73 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
74 INT337079 Negative_regulation of Gene_expression of Mif 1 0.41 4.17 0.51
75 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
76 INT281589 Localization of Foxo3 2 0.61 7.91 0.42
77 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
78 INT116735 Positive_regulation of Positive_regulation of Mif 1 0.70 0.61 0.38
79 INT164261 Binding of NDRG1 3 0.37 0.87 0.37
80 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
81 INT310379 Negative_regulation of FOXO3 2 0.42 1.28 0.32
82 INT253977 Positive_regulation of Binding of Mif 1 0.48 0.97 0.32
83 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
84 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
85 INT297904 Positive_regulation of Foxo3 6 0.57 8.19 0.29
86 INT281598 Negative_regulation of Phosphorylation of Foxo3 2 0.48 4.26 0.28
87 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
88 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
89 INT121366 Regulation of Transcription of Mif 1 0.02 0.61 0.24
90 INT121367 Negative_regulation of Transcription of Mif 1 0.02 0.59 0.24
91 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
92 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
93 INT337077 Positive_regulation of Localization of Mif 1 0.58 0.96 0.21
94 INT275394 Negative_regulation of NDRG1 1 0.01 0.91 0.21
95 INT219470 Positive_regulation of FOXO3 6 0.61 2.83 0.18
96 INT318235 Positive_regulation of Gene_expression of FOXO3 4 0.54 2.59 0.18
97 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
98 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
99 INT260849 Gene_expression of NBN 9 0.67 7.11 0.16
100 INT297906 Binding of Foxo3 2 0.29 1.91 0.16
101 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
102 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
103 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
104 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
105 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
106 INT300285 Positive_regulation of Localization of Foxo3 1 0.38 1.86 0.12
107 INT337076 Positive_regulation of Negative_regulation of Mif 1 0.48 1.44 0.12
108 INT231413 Negative_regulation of NBN 3 0.46 4.6 0.11
109 INT307233 Localization of BCL3 1 0.19 0.84 0.11
110 INT281605 Regulation of Foxo3 2 0.50 2.35 0.1
111 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
112 INT318233 Gene_expression of FOXO3 6 0.60 4.37 0.09
113 INT111139 Localization of Tp53 4 0.45 2.4 0.09
114 INT300288 Positive_regulation of Positive_regulation of Foxo3 1 0.57 1.91 0.09
115 INT231412 Positive_regulation of NBN 3 0.55 3.13 0.07
116 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
117 INT300290 Positive_regulation of Phosphorylation of Foxo3 1 0.41 4.25 0.06
118 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05
119 INT307236 Negative_regulation of Localization of BCL3 1 0.10 0.33 0.05
120 INT273525 Regulation of NBN 1 0.49 1.28 0.05
121 INT315213 Negative_regulation of Binding of Trp53 1 0.32 0.11 0.05
122 INT311668 Regulation of Regulation of TP53 2 0.36 3.58 0.04
123 INT174340 Protein_catabolism of Mif 1 0.89 0.09 0.04
124 INT305536 Positive_regulation of Binding of Trp53 1 0.35 0.32 0.04
125 INT217802 Regulation of Transcription of TP53 2 0.37 0.81 0.03
126 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03
127 INT300293 Positive_regulation of Regulation of Foxo3 1 0.38 0.88 0.03
128 INT300299 Regulation of Phosphorylation of Foxo3 1 0.32 0.89 0.03
129 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0
130 INT333669 Positive_regulation of Transcription of Trp53 3 0.45 2.33 0
131 INT213578 Binding of FOXO3 3 0.33 2.2 0
132 INT277373 Phosphorylation of FOXO3 3 0.72 0.61 0
133 INT250698 Positive_regulation of Transcription of TP53 3 0.18 3.68 0
134 INT113348 Negative_regulation of Binding of TP53 2 0.28 1.49 0
135 INT214913 Positive_regulation of Positive_regulation of Tp53 2 0.08 2.47 0
136 INT217820 Regulation of Negative_regulation of TP53 2 0.37 1.92 0
137 INT322522 Regulation of Positive_regulation of FOXO3 1 0.15 0 0
138 INT204059 Positive_regulation of Phosphorylation of Tp53 1 0.07 0.76 0
139 INT322531 Regulation of FOXO3 1 0.24 0.09 0
140 INT333668 Regulation of Protein_catabolism of Trp53 1 0.24 1.58 0
141 INT260848 Transcription of NBN 1 0.57 0.54 0
142 INT320730 Positive_regulation of Gene_expression of NBN 1 0.60 1.84 0
143 INT353329 Positive_regulation of Regulation of Mif 1 0.36 0 0
144 INT260850 Regulation of Gene_expression of NBN 1 0.38 0.57 0
145 INT333671 Regulation of Transcription of Trp53 1 0.24 0.83 0
146 INT300296 Negative_regulation of Foxo3 1 0.35 1.77 0
147 INT169276 Localization of NBN 1 0.08 0.08 0
148 INT179076 Negative_regulation of Protein_catabolism of Trp53 1 0.32 0.43 0
149 INT337082 Phosphorylation of Mif 1 0.68 0.97 0
150 INT322528 Positive_regulation of Localization of FOXO3 1 0.24 0.09 0
151 INT300292 Transcription of Foxo3 1 0.59 0.77 0
152 INT179957 Positive_regulation of Binding of Tp53 1 0.08 0.48 0
153 INT333663 Positive_regulation of Protein_catabolism of Trp53 1 0.45 0.84 0
154 INT273522 Negative_regulation of Gene_expression of NBN 1 0.34 0.91 0
155 INT333662 Negative_regulation of Transcription of Trp53 1 0.53 1.15 0
156 INT322529 Localization of FOXO3 1 0.38 1.18 0
157 INT307232 Negative_regulation of BCL3 1 0.09 0.24 0
158 INT300289 Positive_regulation of Transcription of Foxo3 1 0.38 0.77 0
159 INT225428 Binding of Paxip1 1 0.21 0.44 0
160 INT223765 Negative_regulation of Positive_regulation of Tp53 1 0.07 1.69 0
161 INT322532 Negative_regulation of Phosphorylation of FOXO3 1 0.23 0.25 0
162 INT305295 Regulation of Binding of TP53 1 0.39 1.09 0
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