GO:0030350

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Name iron-responsive element binding
Categary Function
Go Slim No
Go Link GO:0030350
Unique Molecular Interactions 14
Total Molecular Interactions 21
Total Single Events 392
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for iron-responsive element binding. They are ordered first by their pain relevance and then by number of times they were reported for iron-responsive element binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT158466 FECH Negative_regulation of Fech 1 0.23 0.57 0.2
2 INT281881 Binding of Aco1 and Ros1 1 0.01 1.93 0.1
3 INT239186 H2 Negative_regulation of Aco1 1 0.00 1.96 0.05
4 INT315541 ACO1 Negative_regulation of Gene_expression of ALAS2 1 0.17 0.18 0
5 INT315534 Binding of ACO1 and ERN1 1 0.01 0.18 0
6 INT252791 Binding of IREB2 and TFRC 1 0.02 1.82 0
7 INT252807 Binding of ACO1 and TFRC 1 0.01 1.83 0
8 INT281880 Binding of Aco1 and Cish 1 0.00 0.16 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for iron-responsive element binding. They are ordered first by their pain relevance and then by number of times they were reported in iron-responsive element binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT120201 Gene_expression of Aco1 54 0.35 26.29 2.95
2 INT110038 Negative_regulation of Aco1 26 0.23 17.41 2.2
3 INT281878 Positive_regulation of Gene_expression of Aco1 35 0.31 17.15 1.98
4 INT40215 Negative_regulation of Fech 9 0.57 8.39 1.85
5 INT202218 Positive_regulation of Aco1 4 0.27 12.31 1.06
6 INT95758 Negative_regulation of ACO1 2 0.51 1.25 0.26
7 INT281874 Localization of Aco1 1 0.32 3.67 0.23
8 INT281876 Regulation of Aco1 4 0.11 4 0.22
9 INT135644 Binding of Aco1 2 0.19 2.6 0.22
10 INT95760 Negative_regulation of Gene_expression of ACO1 1 0.00 0.93 0.2
11 INT281872 Positive_regulation of Positive_regulation of Aco1 1 0.20 1.3 0.12
12 INT131139 Binding of ACO1 3 0.27 1.81 0.1
13 INT95756 Gene_expression of ACO1 3 0.27 2.49 0.1
14 INT131140 Negative_regulation of Negative_regulation of ACO1 1 0.37 0.58 0.09
15 INT3782 Regulation of Fech 1 0.00 1.05 0.09
16 INT239158 Negative_regulation of Positive_regulation of Aco1 2 0.17 1.26 0.05
17 INT252699 Gene_expression of IREB2 1 0.11 1.79 0.05
18 INT252720 Negative_regulation of IREB2 1 0.06 0.82 0.05
19 INT281875 Negative_regulation of Gene_expression of Aco1 1 0.17 0.48 0.05
20 INT252724 Negative_regulation of Gene_expression of IREB2 1 0.06 0.89 0.05
21 INT281877 Regulation of Localization of Aco1 1 0.18 1.36 0.04
22 INT281871 Positive_regulation of Localization of Aco1 1 0.20 1.37 0.04
23 INT252722 Binding of IREB2 2 0.16 1.31 0
24 INT315631 Protein_catabolism of IREB2 1 0.44 0.4 0
25 INT315623 Positive_regulation of Localization of ACO1 1 0.20 0.79 0
26 INT321658 Positive_regulation of Fech 1 0.02 0.8 0
27 INT315588 Regulation of ACO1 1 0.18 0.57 0
28 INT323587 Transcription of Aco1 1 0.03 0.1 0
29 INT321657 Positive_regulation of Positive_regulation of Fech 1 0.02 0.8 0
30 INT252749 Regulation of Gene_expression of ACO1 1 0.02 0.9 0
31 INT315574 Localization of ACO1 1 0.30 0.79 0
32 INT315616 Positive_regulation of Gene_expression of ACO1 1 0.20 0.79 0
33 INT315572 Positive_regulation of ACO1 1 0.20 0.94 0
34 INT323585 Regulation of Transcription of Aco1 1 0.02 0.1 0
35 INT315632 Positive_regulation of Protein_catabolism of IREB2 1 0.22 0.4 0
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