GO:0030433

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Name ER-associated protein catabolic process
Categary Process
Go Slim No
Go Link GO:0030433
Unique Molecular Interactions 72
Total Molecular Interactions 101
Total Single Events 649
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for ER-associated protein catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for ER-associated protein catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT51497 Cck Negative_regulation of Localization of Trim13 1 0.34 0 4.53
2 INT42727 Binding of Oprm1 and Trim13 1 0.14 0 2.54
3 INT57824 Binding of Trim13 and Slc25a2 1 0.01 0.08 1.19
4 INT20929 Binding of Trim13 and Vas1 1 0.10 0 1.18
5 INT57823 Binding of Trim13 and Atxn2l 1 0.00 0.08 1.17
6 INT12684 Binding of Bcar3 and Trim13 1 0.03 0 1.08
7 INT46540 TRIM13 Positive_regulation of GPANK1 1 0.05 0 0.83
8 INT72387 Trim13 Regulation of Phosphorylation of Shc1 1 0.32 0.09 0.54
9 INT151558 ERLEC1 Regulation of Atp2a1 1 0.00 0.64 0.53
10 INT151553 ERLEC1 Regulation of DNAH8 1 0.00 0.64 0.5
11 INT20221 Binding of Grcc10 and Fbxo6 1 0.00 0 0.42
12 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
13 INT350835 Binding of SELS and Sels 1 0.16 1.24 0.26
14 INT333927 GLUL Positive_regulation of HSPA5 1 0.17 0.78 0.24
15 INT175324 Hsp90b1 Positive_regulation of TLR2 1 0.00 0.65 0.23
16 INT175317 Hsp90b1 Positive_regulation of Tlr4 1 0.02 0.66 0.23
17 INT224431 TNF Positive_regulation of Gene_expression of FBXO2 1 0.47 0.35 0.22
18 INT224452 Il1 Positive_regulation of Gene_expression of FBXO2 1 0.37 0.35 0.22
19 INT116469 VEGFA Positive_regulation of Amfr 1 0.01 1.39 0.21
20 INT116466 Vegfa Positive_regulation of Amfr 1 0.07 1.41 0.21
21 INT256706 Binding of Hsp90b1 and Wfs1 1 0.43 5.02 0.2
22 INT308518 HSP90B1 Positive_regulation of Positive_regulation of SOAT1 1 0.00 0.65 0.18
23 INT324820 Hsp90b1 Positive_regulation of Tlr2 1 0.16 0.42 0.17
24 INT130690 Gene_expression of HSPA5 Negative_regulation of Positive_regulation of DDIT3 1 0.21 0.58 0.17
25 INT342518 HSP90B1 Positive_regulation of Gene_expression of TLR4 1 0.04 0.4 0.13
26 INT324807 Binding of Tlr4 and Hsp90b1 1 0.10 0.36 0.13
27 INT342520 HSP90B1 Positive_regulation of Gene_expression of TLR2 1 0.06 0.4 0.13
28 INT350820 INS Regulation of SELS 1 0.13 1.11 0.1
29 INT32030 Binding of CEL and ERLEC1 1 0.08 0.42 0.1
30 INT87037 Binding of FBXO6 and Col5a3 1 0.00 0.48 0.09
31 INT142803 Binding of Cog1 and Erlec1 1 0.14 0.16 0.08
32 INT228415 Binding of Ugcg and Erlec1 1 0.00 0.79 0.07
33 INT313807 Binding of TYRP1 and YOD1 1 0.00 0.49 0.06
34 INT313804 Binding of VARS and YOD1 1 0.00 0.49 0.06
35 INT313806 Binding of TYR and YOD1 1 0.01 0.49 0.06
36 INT310547 Binding of TCN1 and ERLIN1 1 0.00 0.17 0.05
37 INT350823 Binding of SAA1 and SELS 1 0.17 2.75 0.05
38 INT257513 Regulation of Binding of Slc4a4 and H47 1 0.00 0.08 0.03
39 INT268710 Binding of RHO and ERLEC1 1 0.00 0.71 0.03
40 INT257512 Binding of Slc4a4 and H47 1 0.00 0.08 0.03
41 INT269838 Binding of Hsp90b1 and Tlr2 1 0.26 1.75 0.03
42 INT342512 Hsp90b1 Positive_regulation of Gene_expression of HSP90B1 1 0.24 0.62 0.03
43 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03
44 INT273519 NBN Negative_regulation of YOD1 1 0.03 0.56 0.03
45 INT256703 Negative_regulation of Hsp90b1 Positive_regulation of Wfs1 1 0.42 0.24 0
46 INT348933 Binding of ALB and ERLEC1 1 0.02 0.47 0
47 INT316774 Hsp90b1 Positive_regulation of Localization of Ddit3 1 0.12 0.17 0
48 INT256700 Negative_regulation of Binding of Hsp90b1 and Wfs1 1 0.52 0 0
49 INT316770 Hsp90b1 Positive_regulation of Ddit3 1 0.12 0.17 0
50 INT333926 Binding of PDIA3 and ERLEC1 1 0.02 0.18 0
51 INT350822 SELS Positive_regulation of Gene_expression of SAA1 1 0.21 0.87 0
52 INT333929 Binding of ESR1 and ERLEC1 1 0.01 0.09 0
53 INT346755 Atf6 Positive_regulation of Hsp90b1 1 0.00 0 0
54 INT313802 Binding of ASIP and YOD1 1 0.00 0.19 0
55 INT256701 Binding of Hsp90aa1 and Hsp90b1 1 0.12 0.34 0
56 INT250554 Binding of F5 and SELS 1 0.24 1.07 0
57 INT348936 Binding of CD59 and ERLEC1 1 0.03 0.48 0
58 INT256705 Binding of Wfs1 and Xbp1 1 0.19 0.39 0
59 INT256632 Binding of PTCH1 and Jkamp 1 0.00 2.32 0
60 INT348934 Binding of ITIH4 and ERLEC1 1 0.03 0.47 0
61 INT350824 INS Positive_regulation of Gene_expression of SELS 1 0.22 0.85 0
62 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0
63 INT256704 Xbp1 Positive_regulation of Positive_regulation of Wfs1 1 0.26 0.4 0
64 INT256702 Binding of Wfs1 and Tmed4 1 0.01 0.61 0
65 INT263868 Binding of Krt31 and H47 1 0.01 0.51 0
66 INT348935 Binding of KNG1 and ERLEC1 1 0.03 0.48 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for ER-associated protein catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in ER-associated protein catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15102 Gene_expression of Trim13 18 0.67 0.43 15.49
2 INT244490 Gene_expression of HSP90B1 4 0.33 41.16 10.37
3 INT1567 Binding of TRIM13 10 0.47 0.24 9.16
4 INT21438 Binding of Trim13 10 0.47 0.26 8.76
5 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
6 INT51494 Localization of Trim13 1 0.60 0 4.36
7 INT2677 Regulation of Trim13 3 0.44 0.5 3.91
8 INT51495 Positive_regulation of Trim13 3 0.41 0.08 3.81
9 INT24160 Gene_expression of TRIM13 7 0.65 1.42 3.46
10 INT250581 Gene_expression of SELS 4 0.78 47.37 3.27
11 INT244512 Positive_regulation of Gene_expression of HSP90B1 2 0.30 12.08 3.12
12 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88
13 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
14 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
15 INT32923 Negative_regulation of Binding of TRIM13 2 0.57 0 2.38
16 INT30385 Protein_catabolism of Trim13 2 0.97 0 2.22
17 INT51496 Negative_regulation of Localization of Trim13 1 0.32 0 2.18
18 INT195968 Positive_regulation of Gene_expression of Hsp90b1 10 0.49 5.21 2.02
19 INT45064 Protein_catabolism of TRIM13 6 0.86 0 1.8
20 INT16782 Binding of ERLEC1 15 0.10 8.23 1.7
21 INT41820 Positive_regulation of TRIM13 3 0.49 0.46 1.65
22 INT66942 Negative_regulation of Protein_catabolism of Trim13 1 0.50 0 1.58
23 INT72377 Phosphorylation of Trim13 1 0.79 0.27 1.57
24 INT34089 Gene_expression of ERLEC1 5 0.14 0.86 1.56
25 INT308527 Regulation of Gene_expression of HSP90B1 2 0.26 5.31 1.46
26 INT23061 Binding of Erlec1 16 0.40 4.2 1.45
27 INT224447 Gene_expression of FBXO2 7 0.75 7.33 1.31
28 INT195977 Transcription of Hsp90b1 5 0.56 1.74 1.27
29 INT60135 Negative_regulation of Protein_catabolism of TRIM13 1 0.30 0 1.1
30 INT1162 Gene_expression of Erlec1 4 0.06 1.25 1.05
31 INT117622 Positive_regulation of HSP90B1 3 0.43 4.84 1.02
32 INT60140 Localization of TRIM13 1 0.53 0 0.94
33 INT159015 Positive_regulation of Localization of HSPA5 1 0.36 0.33 0.88
34 INT159013 Localization of HSPA5 2 0.42 0.32 0.87
35 INT32948 Negative_regulation of Binding of Trim13 1 0.41 0 0.86
36 INT41819 Regulation of TRIM13 2 0.44 0.2 0.85
37 INT99156 Binding of HSPA5 3 0.38 0.57 0.84
38 INT337008 Binding of HSP90B1 2 0.20 4.91 0.81
39 INT20983 Positive_regulation of ERLEC1 3 0.43 1.65 0.74
40 INT29924 Negative_regulation of Gene_expression of Trim13 1 0.34 0 0.74
41 INT256673 Positive_regulation of Hsp90b1 12 0.49 8.49 0.68
42 INT342507 Regulation of HSP90B1 1 0.26 2.29 0.67
43 INT256690 Binding of Hsp90b1 11 0.30 5.94 0.55
44 INT33731 Negative_regulation of TRIM13 1 0.41 0.26 0.55
45 INT72378 Positive_regulation of Phosphorylation of Trim13 1 0.49 0.08 0.51
46 INT15047 Negative_regulation of SELS 1 0.35 0.34 0.49
47 INT222077 Regulation of Hsp90b1 9 0.37 4.78 0.45
48 INT130698 Negative_regulation of Positive_regulation of HSPA5 2 0.36 1.58 0.42
49 INT244505 Regulation of Transcription of HSP90B1 2 0.19 1.47 0.41
50 INT40183 Regulation of Binding of Trim13 1 0.44 0 0.41
51 INT100254 Binding of SELS 6 0.36 4.54 0.4
52 INT244495 Transcription of HSP90B1 2 0.28 1.47 0.4
53 INT1161 Regulation of Gene_expression of Erlec1 1 0.03 0 0.37
54 INT256681 Regulation of Wfs1 8 0.43 4.72 0.36
55 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36
56 INT222080 Regulation of Gene_expression of Hsp90b1 3 0.50 1.22 0.34
57 INT26173 Regulation of SELS 3 0.52 3.4 0.32
58 INT142801 Positive_regulation of Erlec1 3 0.37 0.88 0.32
59 INT350833 Positive_regulation of Gene_expression of SELS 1 0.61 6.07 0.32
60 INT141351 Negative_regulation of Erlec1 2 0.20 0.49 0.3
61 INT316764 Localization of Hsp90b1 1 0.53 1.53 0.28
62 INT333957 Regulation of HSPA5 3 0.52 0.61 0.27
63 INT342508 Negative_regulation of Gene_expression of HSP90B1 1 0.25 1.81 0.26
64 INT256682 Gene_expression of Wfs1 1 0.74 6.63 0.25
65 INT316765 Regulation of Localization of Hsp90b1 1 0.32 0.95 0.25
66 INT332006 Positive_regulation of Gene_expression of Erlec1 1 0.04 1.11 0.25
67 INT350825 Gene_expression of Sels 1 0.34 1.07 0.25
68 INT224449 Positive_regulation of Gene_expression of FBXO2 3 0.49 1.72 0.24
69 INT26381 Positive_regulation of Fbxo6 1 0.04 0 0.22
70 INT342506 Localization of HSP90B1 1 0.34 0.73 0.22
71 INT142482 Positive_regulation of Positive_regulation of HSPA5 1 0.28 1.17 0.22
72 INT76177 Binding of YOD1 2 0.15 1.29 0.21
73 INT305975 Regulation of Gene_expression of SELS 2 0.60 3.19 0.21
74 INT350827 Localization of SELS 1 0.62 1.24 0.19
75 INT144672 Gene_expression of Hsp90b1 1 0.57 1.12 0.19
76 INT224448 Positive_regulation of FBXO2 1 0.49 0.72 0.19
77 INT185753 Negative_regulation of YOD1 4 0.03 1.67 0.17
78 INT20209 Binding of Fbxo6 2 0.00 2.05 0.17
79 INT305978 Protein_catabolism of SELS 1 0.86 0.88 0.17
80 INT256696 Positive_regulation of Wfs1 1 0.66 9.14 0.17
81 INT256684 Positive_regulation of Gene_expression of Wfs1 1 0.66 3.62 0.16
82 INT342503 Negative_regulation of HSP90B1 1 0.18 1.41 0.16
83 INT87034 Positive_regulation of FBXO6 2 0.38 0.89 0.14
84 INT191137 Binding of H47 4 0.19 1.22 0.13
85 INT350834 Transcription of SELS 1 0.53 4.8 0.13
86 INT350832 Positive_regulation of Transcription of SELS 1 0.41 1 0.13
87 INT169910 Positive_regulation of H47 1 0.17 1.52 0.12
88 INT250570 Negative_regulation of Gene_expression of SELS 2 0.43 2.85 0.1
89 INT144669 Positive_regulation of Gene_expression of Hsp90b1 1 0.51 0.59 0.1
90 INT169948 Gene_expression of H47 6 0.22 0.73 0.09
91 INT144670 Positive_regulation of Hsp90b1 1 0.51 0.53 0.09
92 INT256675 Regulation of Gene_expression of Wfs1 1 0.43 2.33 0.09
93 INT256687 Positive_regulation of Transcription of Wfs1 1 0.44 1.95 0.09
94 INT310549 Positive_regulation of ERLIN1 1 0.05 0.17 0.08
95 INT256693 Transcription of Wfs1 1 0.68 2.44 0.08
96 INT256683 Negative_regulation of Gene_expression of Hsp90b1 2 0.35 0.67 0.07
97 INT129588 Localization of Erlec1 1 0.03 0.3 0.07
98 INT333944 Regulation of Regulation of HSPA5 1 0.38 0.14 0.07
99 INT256695 Regulation of Regulation of Hsp90b1 1 0.22 1.69 0.07
100 INT316761 Positive_regulation of Binding of Hsp90b1 1 0.35 0.8 0.05
101 INT337002 Positive_regulation of Binding of HSPA5 1 0.14 0.05 0.05
102 INT191149 Positive_regulation of Binding of H47 1 0.07 0.55 0.05
103 INT191140 Negative_regulation of Binding of H47 1 0.06 0.56 0.05
104 INT130701 Negative_regulation of Gene_expression of HSPA5 1 0.50 0.5 0.05
105 INT310552 Positive_regulation of Binding of ERLIN1 1 0.05 0.15 0.04
106 INT310550 Binding of ERLIN1 1 0.04 0.15 0.04
107 INT342509 Positive_regulation of Binding of HSP90B1 1 0.21 0.19 0.03
108 INT169923 Negative_regulation of Positive_regulation of H47 1 0.12 0.72 0.03
109 INT256680 Negative_regulation of Hsp90b1 4 0.47 1.43 0
110 INT20206 Gene_expression of Fbxo6 2 0.01 0.08 0
111 INT25419 Regulation of FBXO6 2 0.04 1.16 0
112 INT79864 Positive_regulation of Protein_catabolism of TRIM13 2 0.31 0 0
113 INT146283 Regulation of ERLIN1 2 0.22 0.06 0
114 INT295098 Localization of Fbxo6 1 0.01 0.05 0
115 INT174713 Positive_regulation of Transcription of Hsp90b1 1 0.26 0.09 0
116 INT225419 Positive_regulation of Gene_expression of H47 1 0.08 0 0
117 INT256676 Regulation of Binding of Wfs1 1 0.43 0.35 0
118 INT244184 Binding of FBXO2 1 0.03 0 0
119 INT256692 Negative_regulation of Wfs1 1 0.41 0 0
120 INT256671 Regulation of Positive_regulation of Wfs1 1 0.59 1.77 0
121 INT174712 Transcription of Hsp90b1 1 0.38 0.7 0
122 INT256686 Binding of Wfs1 1 0.46 0.91 0
123 INT256689 Positive_regulation of Regulation of Hsp90b1 1 0.38 0.45 0
124 INT87036 Gene_expression of FBXO6 1 0.00 0.17 0
125 INT350829 Regulation of Regulation of SELS 1 0.27 1.39 0
126 INT285194 Localization of ERLEC1 1 0.01 0.07 0
127 INT310551 Gene_expression of ERLIN1 1 0.06 0 0
128 INT256677 Regulation of Transcription of Wfs1 1 0.59 0.5 0
129 INT169932 Positive_regulation of Positive_regulation of H47 1 0.13 0.26 0
130 INT256685 Positive_regulation of Negative_regulation of Hsp90b1 1 0.41 0.24 0
131 INT174714 Regulation of Hsp90b1 1 0.14 0.15 0
132 INT310553 Localization of ERLIN1 1 0.07 0 0
133 INT143737 Positive_regulation of SELS 1 0.67 0.06 0
134 INT256674 Regulation of Binding of Hsp90b1 1 0.37 0.35 0
135 INT244181 Localization of FBXO2 1 0.05 0 0
136 INT337007 Negative_regulation of Binding of HSPA5 1 0.14 0 0
137 INT120782 Negative_regulation of ERLIN1 1 0.16 0 0
138 INT169950 Regulation of H47 1 0.07 0.1 0
139 INT256672 Positive_regulation of Positive_regulation of Wfs1 1 0.44 0.24 0
140 INT169924 Regulation of Gene_expression of H47 1 0.15 0.1 0
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