GO:0030485

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Name smooth muscle contractile fiber
Categary Component
Go Slim No
Go Link GO:0030485
Unique Molecular Interactions 32
Total Molecular Interactions 38
Total Single Events 820
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for smooth muscle contractile fiber. They are ordered first by their pain relevance and then by number of times they were reported for smooth muscle contractile fiber. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
2 INT137022 Pscs Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
3 INT220051 Fcgr4 Positive_regulation of Gene_expression of Ido1 1 0.01 1.24 0.55
4 INT137016 Il6 Positive_regulation of Gene_expression of Acta2 1 0.01 0.75 0.54
5 INT147279 Binding of Calca and Pecam1 1 0.33 0.4 0.47
6 INT104447 Ido1 Negative_regulation of Binding of Atp7b 1 0.00 0.68 0.43
7 INT147280 Binding of Pecam1 and Th 1 0.29 0.41 0.41
8 INT220050 Ctla4 Positive_regulation of Ido1 1 0.31 1.45 0.38
9 INT137023 Gene_expression of SMAD2 Negative_regulation of Gene_expression of Acta2 1 0.00 0.43 0.29
10 INT137021 Positive_regulation of Pscs Positive_regulation of Gene_expression of Acta2 1 0.00 0.42 0.28
11 INT170258 Pecam1 Positive_regulation of Icam1 1 0.02 0.79 0.27
12 INT270046 Ido1 Positive_regulation of Positive_regulation of Hmox1 1 0.15 0.8 0.27
13 INT137011 Il6 Positive_regulation of Acta2 1 0.00 0.34 0.22
14 INT220053 Il10 Positive_regulation of Ido1 1 0.14 0.74 0.19
15 INT323345 Ido1 Positive_regulation of Gene_expression of Tlr4 1 0.14 0.69 0.13
16 INT268083 Ido1 Negative_regulation of Tyrp1 1 0.22 0 0.13
17 INT268082 Ido1 Positive_regulation of Gpr35 1 0.04 0 0.13
18 INT234060 Nes Positive_regulation of Pecam1 1 0.34 0.08 0.11
19 INT118052 Binding of Pecam1 and Cd34 1 0.22 0.51 0.1
20 INT170330 Regulation of Regulation of Gene_expression of Ido1 1 0.01 0.38 0.08
21 INT226906 Binding of Ido1 and Il6 1 0.07 0.67 0.08
22 INT291837 Binding of Pecam1 and Vegfa 1 0.09 1.1 0.07
23 INT268088 Tdo2 Positive_regulation of Gene_expression of Ido1 1 0.41 0.09 0.04
24 INT170328 Gene_expression of Ido1 Positive_regulation of Hmga2 1 0.01 0.13 0.04
25 INT170337 Gene_expression of Ido1 Positive_regulation of MRXS5 1 0.01 0.12 0.03
26 INT170326 Ido1 Positive_regulation of Cpox 1 0.07 0.12 0.03
27 INT170338 Gene_expression of Ido1 Positive_regulation of IGHD2-15 1 0.02 0.12 0.03
28 INT170327 Ido1 Positive_regulation of Gene_expression of Cpox 1 0.07 0.12 0.03
29 INT213746 Binding of Pecam1 and Epc1 1 0.09 0 0
30 INT143144 Prkcg Negative_regulation of Gene_expression of Acta2 1 0.00 0.15 0
31 INT296210 Binding of Pecam1 and Tg(CAG-EGFP)D4Nagy 1 0.01 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for smooth muscle contractile fiber. They are ordered first by their pain relevance and then by number of times they were reported in smooth muscle contractile fiber. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT170308 Gene_expression of Ido1 159 0.75 69.51 15.98
2 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21
3 INT82684 Positive_regulation of Pecam1 27 0.49 25.67 11.47
4 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01
5 INT170295 Positive_regulation of Ido1 40 0.67 28.89 7.61
6 INT102351 Regulation of Pecam1 7 0.61 22.45 7.58
7 INT85968 Positive_regulation of Pecam1 19 0.69 29.04 7.5
8 INT92916 Gene_expression of Acta2 50 0.74 17.52 6.11
9 INT170315 Positive_regulation of Gene_expression of Ido1 50 0.67 25.39 6.06
10 INT11298 Gene_expression of Ido1 6 0.58 6.71 4.85
11 INT170311 Negative_regulation of Ido1 16 0.48 14.47 4.81
12 INT143557 Positive_regulation of Ido1 6 0.40 5.34 4.8
13 INT111993 Positive_regulation of Gene_expression of Acta2 17 0.22 5.02 2.73
14 INT84881 Positive_regulation of Gene_expression of Pecam1 5 0.46 5.79 2.35
15 INT170323 Regulation of Gene_expression of Ido1 11 0.60 8.74 2.33
16 INT102979 Negative_regulation of Gene_expression of Pecam1 5 0.40 4.95 2.21
17 INT143561 Positive_regulation of Positive_regulation of Ido1 1 0.36 1.84 1.89
18 INT150248 Positive_regulation of Gene_expression of Ido1 2 0.43 2.68 1.77
19 INT113147 Positive_regulation of Acta2 6 0.34 4.24 1.66
20 INT67708 Binding of Pecam1 9 0.32 3.12 1.58
21 INT85967 Positive_regulation of Gene_expression of Pecam1 6 0.50 6.22 1.39
22 INT269185 Regulation of Gene_expression of Pecam1 2 0.45 3.75 1.24
23 INT151513 Negative_regulation of Gene_expression of Pecam1 8 0.37 4.73 1.22
24 INT349026 Positive_regulation of Regulation of Pecam1 1 0.46 3.9 1.17
25 INT220046 Positive_regulation of Negative_regulation of Ido1 1 0.41 2.98 1.12
26 INT88177 Negative_regulation of Ido1 3 0.25 0.51 1.02
27 INT102978 Negative_regulation of Pecam1 2 0.48 2.24 1.01
28 INT167375 Localization of Acta2 3 0.73 1.62 0.86
29 INT220043 Positive_regulation of Positive_regulation of Ido1 2 0.41 1.94 0.83
30 INT143559 Positive_regulation of Protein_catabolism of Ido1 1 0.29 0.93 0.79
31 INT143560 Protein_catabolism of Ido1 1 0.52 0.93 0.79
32 INT120861 Negative_regulation of Gene_expression of Acta2 5 0.11 1.24 0.78
33 INT143558 Negative_regulation of Negative_regulation of Ido1 1 0.25 0.49 0.76
34 INT320992 Positive_regulation of Positive_regulation of Pecam1 5 0.50 4.23 0.73
35 INT167378 Positive_regulation of Localization of Acta2 2 0.21 1.37 0.73
36 INT349025 Regulation of Regulation of Pecam1 1 0.27 1.51 0.52
37 INT170299 Negative_regulation of Gene_expression of Ido1 12 0.57 2.59 0.5
38 INT114831 Localization of Pecam1 3 0.65 3.85 0.47
39 INT220048 Protein_catabolism of Ido1 1 0.81 1.03 0.47
40 INT187466 Localization of Pecam1 6 0.47 1.65 0.46
41 INT144101 Negative_regulation of Negative_regulation of Pecam1 1 0.43 1.96 0.46
42 INT91152 Regulation of Pecam1 4 0.30 4.14 0.42
43 INT144100 Negative_regulation of Pecam1 4 0.59 3.65 0.42
44 INT270034 Negative_regulation of Positive_regulation of Ido1 1 0.19 2.23 0.42
45 INT270027 Regulation of Positive_regulation of Ido1 1 0.23 1.17 0.39
46 INT170318 Regulation of Ido1 6 0.38 2.63 0.38
47 INT253290 Negative_regulation of Binding of Pecam1 1 0.31 2.86 0.32
48 INT159362 Binding of Pecam1 2 0.23 0.89 0.27
49 INT98901 Binding of Acta2 2 0.07 1.08 0.26
50 INT349024 Protein_catabolism of Pecam1 1 0.88 0.35 0.25
51 INT11299 Binding of Ido1 1 0.31 0.15 0.15
52 INT114832 Positive_regulation of Localization of Pecam1 1 0.40 1.6 0.11
53 INT170320 Binding of Ido1 1 0.36 0.19 0.11
54 INT170297 Positive_regulation of Regulation of Ido1 1 0.39 0.29 0.1
55 INT339608 Localization of Ido1 1 0.14 0.41 0.08
56 INT68584 Regulation of Acta2 1 0.06 1.09 0.08
57 INT278237 Positive_regulation of Binding of Acta2 1 0.03 0.1 0.05
58 INT325664 Regulation of Positive_regulation of Pecam1 1 0.27 0.57 0.04
59 INT325667 Regulation of Binding of Pecam1 1 0.27 0.62 0.03
60 INT111994 Regulation of Gene_expression of Acta2 2 0.01 0.06 0
61 INT128707 Negative_regulation of Acta2 2 0.01 0.07 0
62 INT102977 Negative_regulation of Positive_regulation of Pecam1 1 0.35 0 0
63 INT179114 Positive_regulation of Phosphorylation of Pecam1 1 0.14 0.45 0
64 INT150246 Negative_regulation of Gene_expression of Ido1 1 0.07 0 0
65 INT325668 Positive_regulation of Phosphorylation of Pecam1 1 0.30 0.41 0
66 INT170301 Negative_regulation of Negative_regulation of Ido1 1 0.36 0.32 0
67 INT170310 Transcription of Ido1 1 0.61 0.52 0
68 INT150247 Transcription of Ido1 1 0.10 0 0
69 INT179108 Phosphorylation of Pecam1 1 0.19 0.45 0
70 INT123315 Transcription of Pecam1 1 0.13 0 0
71 INT150249 Negative_regulation of Transcription of Ido1 1 0.08 0 0
72 INT123316 Transcription of Pecam1 1 0.14 0 0
73 INT104463 Regulation of Gene_expression of Pecam1 1 0.44 0.19 0
74 INT128708 Transcription of Acta2 1 0.00 0 0
75 INT325671 Phosphorylation of Pecam1 1 0.48 0.41 0
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