GO:0030501

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Name positive regulation of bone mineralization
Categary Process
Go Slim No
Go Link GO:0030501
Unique Molecular Interactions 451
Total Molecular Interactions 603
Total Single Events 5644
Pain Genes Associated 43

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of bone mineralization. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of bone mineralization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
2 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
3 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
4 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
5 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
6 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
7 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
8 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
9 INT193288 CAP1 Positive_regulation of Pth 1 0.04 0.08 1.14
10 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
11 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
12 INT165941 Bmp7 Positive_regulation of Penk 1 0.28 0.43 0.95
13 INT165942 Bmp7 Positive_regulation of Transcription of Pomc 1 0.29 0.43 0.95
14 INT165940 Bmp7 Positive_regulation of Pomc 1 0.29 0.43 0.95
15 INT210783 Bmp2 Positive_regulation of Tnip1 1 0.40 0.53 0.94
16 INT210791 Bmp2 Positive_regulation of Net1 1 0.38 0.52 0.93
17 INT210799 Bmp2 Positive_regulation of B2m 1 0.35 0.52 0.92
18 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
19 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
20 INT186672 IL8 Positive_regulation of Transcription of PTH 1 0.01 1.83 0.85
21 INT270218 P2rx3 Positive_regulation of Pla2g4a 1 0.34 0.63 0.85
22 INT42865 Binding of Adrb2 and Man2a2 1 0.23 1.03 0.85
23 INT215598 Positive_regulation of P2rx7 Positive_regulation of Localization of TNF 1 0.22 1.44 0.85
24 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
25 INT42864 Regulation of Binding of Adrb2 and Man2a2 1 0.28 1.03 0.85
26 INT193275 Phax Regulation of Pth 1 0.01 0.16 0.81
27 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
28 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
29 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
30 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
31 INT281241 Positive_regulation of P2RX7 Negative_regulation of Gene_expression of P2rx3 1 0.03 0.79 0.71
32 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
33 INT207540 Tfap2a Regulation of Oprm1 1 0.13 0.06 0.7
34 INT135207 Gmeb1 Regulation of Gene_expression of Tfap2a 1 0.07 0.48 0.69
35 INT135206 Ighen Regulation of Gene_expression of Tfap2a 1 0.06 0.48 0.69
36 INT135202 Tfap2a Regulation of Gene_expression of Ighen 1 0.06 0.48 0.69
37 INT135213 Tfap2a Regulation of Gene_expression of Nfkb1 1 0.02 0.48 0.69
38 INT135211 Nfkb1 Regulation of Gene_expression of Tfap2a 1 0.02 0.48 0.69
39 INT135204 Tfap2a Regulation of Gene_expression of Gmeb1 1 0.10 0.48 0.69
40 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
41 INT207543 Tfap2a Regulation of Qsox1 1 0.04 0.06 0.67
42 INT246335 Fig4 Regulation of Localization of P2rx7 1 0.01 0 0.67
43 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
44 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
45 INT259776 Fbn2 Regulation of Negative_regulation of Agtr1a 1 0.00 1.42 0.66
46 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
47 INT193289 CAP1 Regulation of Pth 1 0.02 0 0.59
48 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
49 INT172144 IL4 Negative_regulation of Transcription of PLA2G4A 1 0.02 0.82 0.58
50 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
51 INT308174 Binding of TNF and P2rx7 1 0.02 0.84 0.56
52 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
53 INT129270 Binding of Wnt4 and Efs 1 0.00 0 0.55
54 INT282821 TACR1 Regulation of P2RX7 1 0.01 2.06 0.54
55 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
56 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
57 INT185490 Atp5o Negative_regulation of Gene_expression of P2rx7 1 0.01 0.87 0.53
58 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53
59 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
60 INT171897 Binding of Bmpr2 and Il1 1 0.03 0.84 0.52
61 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
62 INT3218 Adrb2 Positive_regulation of Localization of Ins1 1 0.10 0 0.52
63 INT66188 Binding of ADRB2 and CDSN 1 0.01 0 0.51
64 INT278122 Negative_regulation of P2rx7 Negative_regulation of Binding of P2RX7 1 0.03 0 0.51
65 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
66 INT244028 Positive_regulation of Binding of Cacnb3 and Tfap2a 1 0.01 0.24 0.49
67 INT244037 Positive_regulation of Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
68 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
69 INT244000 Positive_regulation of Binding of Tfap2a and Dnm1 1 0.04 0.24 0.49
70 INT244035 Binding of Prkaca and Tfap2a 1 0.01 0.24 0.49
71 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
72 INT243997 Binding of Tfap2a and Dnm1 1 0.03 0.24 0.49
73 INT244060 Binding of Cacnb3 and Tfap2a 1 0.00 0.24 0.49
74 INT210793 Bmp2 Positive_regulation of Tsc22d3 1 0.32 0.26 0.46
75 INT35167 Adrb2 Positive_regulation of Trh 1 0.05 0 0.45
76 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
77 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
78 INT146276 Binding of P2RX4 and P2RX7 1 0.38 0.38 0.43
79 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
80 INT169859 P2rx7 Regulation of Gene_expression of Grin1 1 0.17 0 0.43
81 INT186673 IL8 Positive_regulation of Positive_regulation of PTH 1 0.01 0.92 0.42
82 INT92744 Binding of ADRB2 and NF2 1 0.00 0.1 0.41
83 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
84 INT81991 Bmpr2 Positive_regulation of Gene_expression of ODF1 1 0.03 1.59 0.41
85 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
86 INT248146 PLA2G6 Negative_regulation of Phosphorylation of PLA2G4A 1 0.07 0.72 0.4
87 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
88 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
89 INT322015 Binding of IL1B and P2RX7 1 0.07 1 0.37
90 INT99292 Pth Positive_regulation of Jun 1 0.10 0.13 0.36
91 INT270220 Negative_regulation of Ephb1 Negative_regulation of Positive_regulation of Pla2g4a 1 0.13 1 0.36
92 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
93 INT194860 BMPR2 Positive_regulation of IL1B 1 0.01 0.61 0.34
94 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
95 INT191128 Positive_regulation of P2RX7 Positive_regulation of Localization of Il1b 1 0.02 0.71 0.34
96 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34
97 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
98 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
99 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
100 INT217041 TNF Positive_regulation of Gene_expression of P2RX7 1 0.50 0.81 0.34
101 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
102 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
103 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
104 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
105 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
106 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
107 INT263974 Binding of ADRB2 and NR4A3 1 0.01 0.5 0.32
108 INT263978 Binding of ADRB2 and TNFAIP3 1 0.01 0.5 0.32
109 INT263979 Binding of ADRB2 and ATF3 1 0.01 0.5 0.32
110 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
111 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
112 INT224687 Il1 Positive_regulation of Bmp2 1 0.00 0.3 0.31
113 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
114 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
115 INT215789 Fig4 Positive_regulation of Localization of P2rx7 1 0.03 0.53 0.29
116 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
117 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
118 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
119 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
120 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
121 INT182817 EEF1A2 Positive_regulation of BMP2 1 0.26 1.62 0.28
122 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
123 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
124 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
125 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
126 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
127 INT16163 Pth Regulation of Gene_expression of Plast4 1 0.00 0.65 0.25
128 INT118461 Bmp7 Positive_regulation of Th 1 0.31 0.06 0.25
129 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
130 INT185489 Atp5o Negative_regulation of P2rx7 1 0.01 0.29 0.24
131 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
132 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
133 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
134 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
135 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
136 INT29099 Binding of ADRB2 and PPAP2A 1 0.03 0.77 0.22
137 INT63192 PTH Positive_regulation of ESR1 1 0.20 0.29 0.22
138 INT63201 PTH Positive_regulation of CD8A 1 0.45 0.29 0.22
139 INT63200 PTH Positive_regulation of IL2 1 0.24 0.29 0.22
140 INT63194 PTH Positive_regulation of PGR 1 0.25 0.29 0.22
141 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
142 INT107219 Binding of P2rx7 and Atp5o 1 0.03 0.07 0.21
143 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
144 INT107223 APEH Negative_regulation of P2rx7 1 0.00 0.13 0.21
145 INT322011 BSG Regulation of P2RX7 1 0.00 0.48 0.21
146 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
147 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
148 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
149 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
150 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
151 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
152 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
153 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
154 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
155 INT349659 PYCARD Positive_regulation of ADRB2 1 0.06 0.19 0.17
156 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
157 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
158 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16
159 INT146744 Binding of NR3C1 and PLA2G4A 1 0.26 0.25 0.15
160 INT128705 Binding of Adrb2 and Ahsg 1 0.00 0.23 0.15
161 INT123180 Bmp6 Positive_regulation of Lamtor1 1 0.01 0.61 0.14
162 INT123192 Bmp6 Positive_regulation of CDKN1A 1 0.18 0.61 0.14
163 INT124412 Binding of PTH and Pth 1 0.02 0.65 0.14
164 INT213551 Proc Regulation of Bmp7 1 0.00 0.15 0.14
165 INT123194 Bmp6 Positive_regulation of TAF9 1 0.18 0.61 0.14
166 INT309779 PTH Negative_regulation of Gene_expression of COL5A2 1 0.00 0.52 0.14
167 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
168 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
169 INT123193 Bmp6 Positive_regulation of Negative_regulation of TAF9 1 0.18 0.61 0.14
170 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
171 INT323430 Binding of Vhl and Osr1 1 0.02 0.78 0.13
172 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
173 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
174 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
175 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
176 INT323435 Binding of Osr1 and Gtf3a 1 0.00 0.78 0.13
177 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
178 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
179 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12
180 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12
181 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
182 INT322037 Binding of P2RX7 and Myh1 1 0.06 0 0.12
183 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
184 INT146743 Positive_regulation of Binding of GSR and PLA2G4A 1 0.40 0.14 0.11
185 INT146742 Binding of GSR and PLA2G4A 1 0.28 0.14 0.11
186 INT74504 Binding of P2rx7 and Rp2 1 0.02 0.19 0.11
187 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
188 INT93535 PTH Negative_regulation of Gene_expression of Tnfsf11 1 0.19 0.22 0.11
189 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11
190 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
191 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1
192 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
193 INT309780 Binding of PTH and PTH1R 3 0.12 0.3 0.09
194 INT238038 Binding of BMP2 and OPLL 1 0.20 2.45 0.09
195 INT299555 Lifr Positive_regulation of Gene_expression of TGFB1 1 0.03 0.23 0.09
196 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
197 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
198 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
199 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
200 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of bone mineralization. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of bone mineralization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT49519 Gene_expression of P2rx7 84 0.76 36.88 34.69
3 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54
4 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26
5 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
6 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
7 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
8 INT23787 Positive_regulation of P2rx7 36 0.68 23.54 19.45
9 INT187513 Positive_regulation of Pla2g4a 5 0.62 34.09 18.22
10 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
11 INT195831 Phosphorylation of Pla2g4a 15 0.74 34.43 17.14
12 INT127046 Gene_expression of P2RX7 65 0.78 34.28 14.76
13 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
14 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
15 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7
16 INT270238 Localization of Pla2g4a 1 0.72 17.99 11.35
17 INT137980 Positive_regulation of P2RX7 30 0.67 22.49 10
18 INT73427 Localization of P2rx7 24 0.79 8.65 9.87
19 INT22083 Regulation of Pth 55 0.62 22.32 8.9
20 INT29411 Positive_regulation of ADRB2 13 0.65 5.42 8.78
21 INT48257 Negative_regulation of P2rx7 18 0.41 7.82 8.42
22 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24
23 INT7883 Binding of ADRB2 18 0.47 5.49 7.37
24 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33
25 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
26 INT94608 Regulation of P2rx7 19 0.23 8.06 6.19
27 INT68882 Binding of P2rx7 16 0.23 4.33 6.17
28 INT1243 Regulation of ADRB2 16 0.54 1.84 5.66
29 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
30 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
31 INT13885 Positive_regulation of Adrb2 9 0.49 1.11 5.12
32 INT62570 Binding of Pth 48 0.48 26.45 4.85
33 INT24930 Binding of Adrb2 6 0.26 4.18 4.44
34 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
35 INT4097 Localization of Pth 66 0.81 47.17 4.36
36 INT185484 Positive_regulation of Gene_expression of P2rx7 8 0.31 7.44 4.28
37 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
38 INT64864 Gene_expression of PLA2G4A 18 0.77 10.45 4.09
39 INT127047 Negative_regulation of P2RX7 10 0.39 7.17 4.01
40 INT484 Negative_regulation of ADRB2 13 0.59 2.85 3.94
41 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
42 INT162125 Gene_expression of Pla2g4a 4 0.54 7.69 3.75
43 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
44 INT6882 Binding of Adrb2 5 0.47 1.97 3.55
45 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
46 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
47 INT141148 Gene_expression of BMP7 24 0.71 14.34 3.44
48 INT16626 Positive_regulation of Adrb2 10 0.30 2.41 3.4
49 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39
50 INT129441 Regulation of Gene_expression of P2rx7 8 0.24 4.29 3.32
51 INT100295 Gene_expression of Bmp7 27 0.78 14.34 3.3
52 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
53 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
54 INT270224 Positive_regulation of Positive_regulation of Pla2g4a 1 0.62 6.63 3.22
55 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
56 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
57 INT28094 Binding of PTH 29 0.37 13.57 3.09
58 INT85809 Gene_expression of BMP2 46 0.78 9.91 3.05
59 INT39990 Negative_regulation of BMP6 1 0.59 0 3.05
60 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01
61 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
62 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
63 INT191120 Regulation of P2RX7 8 0.41 5.29 2.96
64 INT41474 Gene_expression of ADRB2 10 0.75 1.56 2.94
65 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
66 INT132773 Negative_regulation of Acvr2b 3 0.41 1.55 2.87
67 INT259760 Localization of Fbn2 5 0.05 5.55 2.85
68 INT137978 Localization of P2RX7 6 0.73 5.04 2.84
69 INT22500 Negative_regulation of Pth 6 0.43 3.41 2.83
70 INT33480 Gene_expression of Adrb2 4 0.66 1.96 2.77
71 INT107216 Negative_regulation of Gene_expression of P2rx7 10 0.56 3.39 2.61
72 INT259762 Positive_regulation of Fbn2 4 0.05 6.74 2.55
73 INT514 Gene_expression of Adrb2 3 0.53 0.23 2.46
74 INT270235 Negative_regulation of Phosphorylation of Pla2g4a 1 0.39 3.4 2.34
75 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31
76 INT3531 Regulation of Adrb2 7 0.44 1.48 2.25
77 INT2544 Localization of PTH 39 0.81 30.55 2.22
78 INT152076 Negative_regulation of Pla2g4a 3 0.55 3.22 2.21
79 INT137972 Binding of P2RX7 12 0.36 8.01 2.18
80 INT70725 Negative_regulation of Binding of ADRB2 3 0.57 0.4 2.14
81 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
82 INT195828 Positive_regulation of Phosphorylation of Pla2g4a 3 0.45 5.05 2.12
83 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
84 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
85 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
86 INT104912 Gene_expression of Acvr2a 8 0.63 4.48 1.81
87 INT40832 Localization of ADRB2 5 0.73 2.21 1.81
88 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
89 INT141385 Positive_regulation of Gene_expression of P2RX7 7 0.62 3.95 1.73
90 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
91 INT3343 Regulation of PTH 24 0.62 11.18 1.62
92 INT23786 Positive_regulation of Positive_regulation of P2rx7 5 0.44 2.21 1.58
93 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
94 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55
95 INT91773 Positive_regulation of PLA2G4A 10 0.50 4.4 1.54
96 INT91764 Positive_regulation of Gene_expression of PLA2G4A 8 0.69 5.43 1.52
97 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
98 INT259766 Positive_regulation of Localization of Fbn2 1 0.03 3.09 1.51
99 INT270223 Negative_regulation of Localization of Pla2g4a 1 0.39 1.83 1.5
100 INT207521 Gene_expression of Tfap2a 7 0.48 1.89 1.45
101 INT215757 Transcription of P2rx7 3 0.21 1.84 1.45
102 INT130014 Positive_regulation of BMP2 11 0.66 5.34 1.42
103 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
104 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
105 INT165538 Binding of Bmp7 5 0.37 1.87 1.39
106 INT287241 Positive_regulation of BMP7 10 0.43 2.68 1.38
107 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37
108 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
109 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
110 INT70619 Regulation of Bmp2 6 0.60 3.1 1.29
111 INT39500 Positive_regulation of Positive_regulation of Pth 14 0.48 9.75 1.28
112 INT52212 Gene_expression of Bmp6 6 0.64 2.38 1.27
113 INT22498 Binding of Pth 2 0.48 2.81 1.24
114 INT39991 Negative_regulation of Negative_regulation of BMP6 1 0.43 0 1.24
115 INT72749 Regulation of Pth 4 0.62 1.39 1.14
116 INT41475 Positive_regulation of Localization of ADRB2 2 0.49 0.18 1.12
117 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11
118 INT82214 Transcription of PTH 6 0.54 3.33 1.11
119 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
120 INT64863 Localization of PLA2G4A 9 0.44 3.33 1.07
121 INT160538 Binding of Bmp2 4 0.40 2.08 1.07
122 INT84511 Positive_regulation of Tfap2a 3 0.27 0.72 1.04
123 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
124 INT195832 Regulation of Phosphorylation of Pla2g4a 3 0.34 2.91 1.02
125 INT49796 Positive_regulation of Binding of Adrb2 1 0.00 0 1.02
126 INT52186 Positive_regulation of Positive_regulation of ADRB2 1 0.14 0 1.02
127 INT49795 Negative_regulation of Binding of Adrb2 1 0.00 0 1.02
128 INT162126 Positive_regulation of Gene_expression of Pla2g4a 4 0.42 2.52 1.01
129 INT216661 Regulation of Positive_regulation of P2rx7 1 0.07 0 1
130 INT191121 Regulation of Gene_expression of P2RX7 3 0.36 3.69 0.99
131 INT23030 Positive_regulation of Pth 13 0.61 9.24 0.97
132 INT65166 Negative_regulation of PLA2G4A 7 0.57 1.55 0.96
133 INT113887 Positive_regulation of Negative_regulation of P2rx7 1 0.22 1.02 0.96
134 INT138548 Negative_regulation of Gene_expression of Adrb2 1 0.41 0.85 0.96
135 INT4096 Regulation of Localization of Pth 7 0.58 3.97 0.95
136 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
137 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
138 INT243974 Binding of Tfap2a 7 0.18 1.36 0.93
139 INT215567 Positive_regulation of Positive_regulation of P2RX7 2 0.45 0.07 0.93
140 INT270236 Regulation of Localization of Pla2g4a 1 0.24 1.68 0.93
141 INT52213 Regulation of Localization of Bmp6 1 0.44 0.39 0.93
142 INT270231 Regulation of Positive_regulation of Pla2g4a 1 0.24 1.92 0.92
143 INT114664 Binding of BMP2 12 0.37 6.54 0.91
144 INT52215 Localization of Bmp6 1 0.73 0.37 0.88
145 INT277586 Negative_regulation of Mef2c 36 0.59 11.03 0.86
146 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
147 INT14976 Negative_regulation of Adrb2 3 0.24 0.75 0.86
148 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
149 INT70726 Positive_regulation of Negative_regulation of ADRB2 1 0.49 0.2 0.86
150 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
151 INT42863 Regulation of Adrb2 1 0.11 1.02 0.85
152 INT42862 Regulation of Binding of Adrb2 1 0.15 1.03 0.85
153 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
154 INT266562 Gene_expression of Fbn2 1 0.05 0.93 0.84
155 INT270226 Negative_regulation of Positive_regulation of Pla2g4a 1 0.38 2.34 0.84
156 INT266563 Positive_regulation of Gene_expression of Fbn2 1 0.04 0.93 0.84
157 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
158 INT221796 Positive_regulation of Gene_expression of Tfap2a 2 0.10 1.19 0.83
159 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
160 INT146746 Transcription of PLA2G4A 3 0.69 1.03 0.8
161 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
162 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
163 INT33481 Positive_regulation of Gene_expression of Adrb2 2 0.48 0.38 0.78
164 INT271589 Regulation of Transcription of P2rx7 1 0.05 0.5 0.78
165 INT278119 Positive_regulation of Localization of P2RX7 2 0.45 1.14 0.77
166 INT141150 Localization of BMP7 4 0.56 2.84 0.76
167 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
168 INT259763 Regulation of Fbn2 1 0.02 1.47 0.76
169 INT207535 Transcription of Tfap2a 3 0.31 0.98 0.74
170 INT114604 Positive_regulation of Acvr2a 2 0.41 0 0.73
171 INT31778 Negative_regulation of Adrb2 2 0.07 1.34 0.72
172 INT135197 Gene_expression of Tfap2a 1 0.45 0.48 0.69
173 INT67452 Positive_regulation of Regulation of ADRB2 1 0.41 0.26 0.68
174 INT202361 Gene_expression of Mef2c 28 0.78 5.53 0.67
175 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
176 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
177 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
178 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
179 INT39994 Positive_regulation of BMP6 1 0.50 0 0.63
180 INT185485 Negative_regulation of Localization of P2rx7 1 0.26 0.95 0.62
181 INT39992 Positive_regulation of Negative_regulation of BMP6 1 0.47 0 0.62
182 INT62067 Negative_regulation of Gene_expression of Pth 13 0.41 8.24 0.61
183 INT100294 Positive_regulation of Gene_expression of Bmp7 8 0.46 5.41 0.61
184 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
185 INT207529 Localization of Tfap2a 2 0.34 0.13 0.6
186 INT39993 Regulation of BMP6 2 0.39 0.29 0.6
187 INT259764 Negative_regulation of Positive_regulation of Fbn2 1 0.03 1.7 0.6
188 INT238049 Positive_regulation of Gene_expression of BMP2 8 0.51 2.06 0.59
189 INT80300 Gene_expression of TFAP2A 5 0.54 2.76 0.59
190 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
191 INT89126 Regulation of BMP7 7 0.45 2.5 0.58
192 INT259765 Phosphorylation of Fbn2 1 0.05 0.99 0.57
193 INT243970 Phosphorylation of Tfap2a 2 0.25 0.56 0.56
194 INT270227 Positive_regulation of Localization of Pla2g4a 1 0.45 1.31 0.56
195 INT19395 Negative_regulation of Localization of Pth 11 0.58 10.16 0.55
196 INT78775 Regulation of PLA2G4A 4 0.25 1.45 0.55
197 INT110924 Regulation of BMPR2 3 0.17 1.75 0.54
198 INT76858 Binding of PLA2G4A 4 0.30 1.22 0.52
199 INT165537 Negative_regulation of Bmp7 2 0.43 0.55 0.52
200 INT85808 Localization of BMP2 7 0.77 1.94 0.51
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