GO:0030502

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Name negative regulation of bone mineralization
Categary Process
Go Slim No
Go Link GO:0030502
Unique Molecular Interactions 228
Total Molecular Interactions 321
Total Single Events 2368
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of bone mineralization. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of bone mineralization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27
2 INT319003 Binding of CCR1 and CCL5 1 0.08 3.38 2.89
3 INT250867 Fgf8 Positive_regulation of Protein_catabolism of Ecm1 1 0.06 4.35 2.14
4 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47
5 INT222213 TFAM Positive_regulation of Gene_expression of Ccr1 1 0.02 3.96 1.4
6 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03
7 INT48341 Negative_regulation of Pde8a Regulation of Ahsg 1 0.22 0 0.9
8 INT48342 Pde8a Regulation of Ahsg 1 0.24 0 0.9
9 INT209035 Il2 Positive_regulation of Ccr1 1 0.00 0.38 0.73
10 INT209038 Il4 Positive_regulation of Ccr1 1 0.01 0.38 0.73
11 INT209065 Il3 Positive_regulation of Ccr1 1 0.00 0.38 0.73
12 INT209031 Il12b Positive_regulation of Ccr1 1 0.02 0.37 0.72
13 INT209041 Il10 Positive_regulation of Ccr1 1 0.01 0.37 0.72
14 INT209060 Il6 Positive_regulation of Ccr1 1 0.01 0.38 0.72
15 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
16 INT120017 CCL2 Positive_regulation of CCL3 1 0.01 0.99 0.7
17 INT120019 IL8 Positive_regulation of CCL3 1 0.02 0.99 0.7
18 INT222211 TFAM Positive_regulation of Ccr1 1 0.02 1.89 0.68
19 INT250871 Il1a Positive_regulation of Protein_catabolism of Ecm1 1 0.01 1.44 0.68
20 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67
21 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67
22 INT102863 Prkaca Regulation of Srgn 1 0.50 0.05 0.64
23 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
24 INT179850 Binding of Ecm1 and Il11 1 0.02 0 0.6
25 INT97635 ABCF1 Positive_regulation of Localization of CCR1 1 0.05 0.51 0.55
26 INT250852 Fgf8 Negative_regulation of Gene_expression of Ecm1 1 0.04 1.1 0.54
27 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47
28 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
29 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
30 INT181447 Ccl3 Positive_regulation of Csf2 1 0.06 1.89 0.45
31 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
32 INT260744 Binding of Ecm1 and Tlr2 1 0.00 0.45 0.39
33 INT181081 Binding of Ccr1 and Darc 1 0.01 1.08 0.39
34 INT260746 Binding of TLR4 and Ecm1 1 0.02 0.44 0.38
35 INT250870 Fgf8 Positive_regulation of Ecm1 1 0.04 0.79 0.38
36 INT187219 Vip Negative_regulation of Gene_expression of Ccl3 1 0.32 0.65 0.35
37 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
38 INT206609 Binding of Col7a1 and Ecm1 1 0.00 0.47 0.33
39 INT206608 Binding of Ecm1 and Itgb5 1 0.02 0.41 0.33
40 INT325221 Il13 Regulation of Ccl3 1 0.08 0.17 0.32
41 INT244233 Ccr1 Positive_regulation of Cxcr1 1 0.16 0.08 0.32
42 INT144500 CCL3 Positive_regulation of Gene_expression of Tnfsf11 1 0.77 1.62 0.31
43 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
44 INT181446 Csf2 Positive_regulation of Ccl3 1 0.05 0.81 0.29
45 INT268766 Tlr4 Positive_regulation of Gene_expression of Ccr1 1 0.04 0.4 0.26
46 INT275553 Negative_regulation of Binding of Ccr5 and Ccl3 1 0.05 0.73 0.26
47 INT237087 Binding of Cxcl9 and Ccl3 1 0.30 1.51 0.26
48 INT118418 Gata1 Positive_regulation of Transcription of Tac2 1 0.61 0.77 0.25
49 INT118419 Binding of Gata1 and Tac2 1 0.31 0.7 0.24
50 INT268768 Mip Regulation of Positive_regulation of Ccr1 1 0.44 0.83 0.23
51 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23
52 INT170993 IL10 Positive_regulation of Gene_expression of CCR1 1 0.12 0.34 0.22
53 INT180670 Cpd Regulation of Protein_catabolism of Ecm1 1 0.04 0.14 0.22
54 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21
55 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
56 INT158209 Binding of CCR1 and AHSA1 1 0.17 0.3 0.2
57 INT158225 Binding of CCR1 and MAPK1 1 0.18 0.3 0.2
58 INT158231 TNFSF14 Positive_regulation of CCR1 1 0.07 0.3 0.2
59 INT158210 Binding of CCR1 and TNFSF14 1 0.05 0.3 0.2
60 INT158212 Negative_regulation of Binding of CCR1 and AHSA1 1 0.20 0.3 0.2
61 INT158200 Positive_regulation of Binding of CCR1 and AHSA1 1 0.23 0.3 0.2
62 INT158201 Positive_regulation of Binding of CCR1 and TNFSF14 1 0.07 0.3 0.2
63 INT158221 Positive_regulation of Binding of CCR1 and MAPK1 1 0.25 0.3 0.2
64 INT158230 Negative_regulation of Binding of CCR1 and TNFSF14 1 0.06 0.3 0.2
65 INT158219 Negative_regulation of Binding of CCR1 and MAPK1 1 0.21 0.3 0.2
66 INT23585 Binding of KRIT1 and CCR1 1 0.40 0.97 0.19
67 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
68 INT244243 Regulation of Binding of IL8 and Ccl3 1 0.04 0.05 0.18
69 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18
70 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18
71 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
72 INT244241 Binding of IL8 and Ccl3 1 0.05 0.05 0.18
73 INT244242 Negative_regulation of Binding of IL8 and Ccl3 1 0.06 0.05 0.18
74 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17
75 INT244235 Binding of Cxcl1 and Ccl3 1 0.14 0.23 0.17
76 INT172250 Binding of APLNR and CCR1 1 0.12 0 0.17
77 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17
78 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15
79 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15
80 INT237418 Binding of Hif1a and Bace1 1 0.06 1.18 0.15
81 INT259628 Cxcl10 Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.64 0.15
82 INT128705 Binding of Adrb2 and Ahsg 1 0.00 0.23 0.15
83 INT221019 ELANE Positive_regulation of CCL3 1 0.00 0.24 0.15
84 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15
85 INT148532 Binding of CCL3 and Tnfsf11 1 0.03 0.71 0.14
86 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13
87 INT268765 Tlr4 Positive_regulation of Positive_regulation of Ccr1 1 0.04 0.27 0.13
88 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13
89 INT250857 Gene_expression of Mmp3 Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.17 0.13
90 INT323434 Osr1 Regulation of Hif1a 1 0.01 0.79 0.13
91 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
92 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13
93 INT323433 Osr1 Regulation of Protein_catabolism of Hif1a 1 0.01 0.8 0.13
94 INT250869 Mia Positive_regulation of Protein_catabolism of Ecm1 1 0.01 0.25 0.12
95 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12
96 INT232787 CYBB Positive_regulation of Positive_regulation of Hif1a 1 0.01 0.66 0.12
97 INT323431 Binding of Hif1a and Vhl 1 0.07 0.68 0.12
98 INT249923 Binding of Pah and Hif1a 1 0.31 1.16 0.12
99 INT336632 Ecm1 Regulation of Regulation of Ahr 1 0.03 0.61 0.11
100 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
101 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11
102 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1
103 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1
104 INT102244 IL36RN Positive_regulation of Binding of HIF1A 1 0.06 1.07 0.1
105 INT102245 TNF Positive_regulation of Binding of HIF1A 1 0.18 1.09 0.1
106 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
107 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1
108 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
109 INT294444 KLK4 Negative_regulation of CCL3 1 0.00 0 0.1
110 INT173061 Binding of HIF1A and LILRA3 1 0.03 1.24 0.09
111 INT324829 ROS1 Positive_regulation of Gene_expression of Ecm1 1 0.00 0.66 0.09
112 INT348686 Plg Positive_regulation of Protein_catabolism of Ecm1 1 0.02 0.17 0.09
113 INT324828 ELANE Positive_regulation of Localization of Ecm1 1 0.00 0.61 0.09
114 INT173062 Binding of HIF1A and VHLL 1 0.04 1.26 0.09
115 INT185644 Binding of STATH and WASF1 1 0.00 0 0.09
116 INT336634 Fbln1 Positive_regulation of Ecm1 1 0.06 1.26 0.09
117 INT173057 Positive_regulation of HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.24 1.49 0.08
118 INT226044 Lta Positive_regulation of Ecm1 1 0.02 0.44 0.08
119 INT249920 Negative_regulation of Binding of Pah and Hif1a 1 0.37 0.76 0.08
120 INT259622 Elane Positive_regulation of Protein_catabolism of Ecm1 1 0.00 0.38 0.08
121 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
122 INT178078 Positive_regulation of Binding of DBP and HIF1A 1 0.00 1 0.08
123 INT304330 TGFB1 Positive_regulation of ECM1 1 0.00 0.31 0.08
124 INT179847 Binding of Ecm1 and Sparc 1 0.04 0 0.08
125 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
126 INT178103 Binding of DBP and HIF1A 1 0.00 0.99 0.07
127 INT268673 Binding of NCOR2 and BCOR 1 0.01 2.54 0.07
128 INT247578 Hif1a Regulation of VEGFA 1 0.02 1.59 0.07
129 INT128706 Binding of MET and Ahsg 1 0.28 0.34 0.07
130 INT118417 Gata1 Regulation of Gene_expression of Serpinb9g 1 0.17 0.12 0.06
131 INT179852 Binding of PTPRC and Ecm1 1 0.00 0 0.05
132 INT226043 Epo Positive_regulation of Ecm1 1 0.04 1.35 0.05
133 INT308328 Hif1a Regulation of Positive_regulation of Trib3 1 0.02 0.89 0.05
134 INT304322 Hif1a Positive_regulation of Positive_regulation of VEGFA 1 0.11 0.39 0.05
135 INT180667 Edn1 Regulation of Ecm1 1 0.04 0 0.05
136 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04
137 INT268676 Binding of HDAC1 and BCOR 1 0.01 1.31 0.04
138 INT249921 Binding of Hif1a and Asph 1 0.05 0.41 0.04
139 INT102247 Binding of EPO and HIF1A 1 0.41 0.65 0.04
140 INT173060 Negative_regulation of VHLL Positive_regulation of Positive_regulation of HIF1A 1 0.04 0.66 0.04
141 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04
142 INT179836 Il11 Regulation of Gene_expression of Ecm1 1 0.05 0 0.04
143 INT336639 PTPRC Positive_regulation of Ecm1 1 0.00 0.62 0.04
144 INT219230 Binding of Ecm1 and Ighv10-3 1 0.00 0.26 0.04
145 INT322891 Sox9 Regulation of Transcription of Col2a1 1 0.10 0.12 0.04
146 INT89385 INS Positive_regulation of Phosphorylation of PTK2B 1 0.15 0.59 0.04
147 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03
148 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03
149 INT316598 Pth Regulation of Fgf23 1 0.10 0.28 0.03
150 INT297159 Gsta3 Negative_regulation of Hif1a 1 0.00 0.54 0.03
151 INT322471 Hif1a Positive_regulation of VEGFA 1 0.05 0.26 0.03
152 INT210260 Sox9 Negative_regulation of Cdx2 1 0.20 0 0.03
153 INT247576 Binding of Hif1a and Vbp1 1 0.01 0.6 0
154 INT189554 Binding of HIF1A and Positive_regulation of EGLN1 1 0.04 0.86 0
155 INT135174 Myst2 Positive_regulation of Binding of Hif1a 1 0.41 0 0
156 INT314865 Binding of Ltbp3 and Tgfb1 1 0.24 0.51 0
157 INT318544 Paics Regulation of Ecm1 1 0.00 1.43 0
158 INT143438 HIF1A Regulation of Gene_expression of VEGFA 1 0.69 0.13 0
159 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0
160 INT268515 MIR221 Positive_regulation of BCOR 1 0.09 1.36 0
161 INT320029 Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1 1 0.03 0 0
162 INT314858 Binding of Gdf11 and Ltbp3 1 0.39 0.31 0
163 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0
164 INT247574 Ube2e3 Positive_regulation of Hif1a 1 0.04 0.62 0
165 INT333879 Shc1 Positive_regulation of SOX9 1 0.01 0 0
166 INT225570 Ncoa6 Regulation of Sox9 1 0.16 0.72 0
167 INT179848 Binding of Ecm1 and Gtf3a 1 0.00 0.19 0
168 INT314862 Binding of Ltbp3 and Tgfb2 1 0.24 0.52 0
169 INT222474 Binding of Fgf1 and Ecm1 1 0.00 0.62 0
170 INT241307 Positive_regulation of HIF1A Positive_regulation of Positive_regulation of EPO 1 0.12 0.64 0
171 INT247575 Binding of Epo and Hif1a 1 0.09 1.24 0
172 INT290478 Mitf Positive_regulation of HIF1A 1 0.57 0.61 0
173 INT314868 Binding of Ltbp2 and Ltbp3 1 0.29 0.54 0
174 INT180672 Sgk1 Regulation of Ecm1 1 0.03 0 0
175 INT135175 Myst2 Positive_regulation of Hif1a 1 0.41 0 0
176 INT189552 EGLN1 Positive_regulation of HIF1A 1 0.05 0.98 0
177 INT260496 Hif1a Regulation of Gene_expression of VEGFA 1 0.12 0.93 0
178 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0
179 INT249924 Cpox Positive_regulation of Hif1a 1 0.01 0.68 0
180 INT314870 Binding of Ltbp3 and Tgfb3 1 0.24 0.52 0
181 INT337352 Binding of ARNT and HIF1A 1 0.14 0.61 0
182 INT119045 HIF1A Regulation of Regulation of TP53 1 0.09 1.06 0
183 INT262710 Binding of Crem and Hif1a 1 0.00 1.85 0
184 INT119046 HIF1A Regulation of TP53 1 0.05 1.06 0
185 INT351678 Nrp1 Regulation of Binding of Ecm1 1 0.00 1.55 0
186 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0
187 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
188 INT351681 Binding of Ecm1 and Fn1 1 0.00 1.14 0
189 INT266839 Fgf23 Negative_regulation of Slc34a1 1 0.21 0.88 0
190 INT143439 Positive_regulation of HIF1A Regulation of Gene_expression of VEGFA 1 0.30 0.13 0
191 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0
192 INT180673 Trib3 Regulation of Ecm1 1 0.02 0 0
193 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0
194 INT290479 Binding of HIF1A and Mitf 1 0.30 1.29 0
195 INT266838 Fgf23 Regulation of Slc34a1 1 0.13 0.3 0
196 INT119044 HIF1A Regulation of TCEAL1 1 0.02 1.06 0
197 INT313884 XRCC1 Positive_regulation of Localization of HIF1A 1 0.00 0.65 0
198 INT245735 SOX9 Regulation of COL5A2 1 0.07 0.29 0
199 INT119047 HIF1A Regulation of Regulation of TCEAL1 1 0.08 1.06 0
200 INT345487 HIF1A Positive_regulation of PMAIP1 1 0.27 1.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of bone mineralization. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of bone mineralization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14
2 INT71680 Gene_expression of CCL3 43 0.75 33.7 18.01
3 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
4 INT20376 Gene_expression of Ccl3 39 0.75 45.42 13.15
5 INT128364 Positive_regulation of Ccl3 20 0.70 23.96 10.65
6 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
7 INT166881 Positive_regulation of Ccr1 31 0.69 18.14 7.9
8 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16
9 INT153271 Localization of Ccl3 7 0.81 11.29 7.14
10 INT93144 Gene_expression of CCR1 18 0.75 14.69 6.84
11 INT141611 Positive_regulation of Gene_expression of Ccr1 25 0.69 20.32 6.42
12 INT171691 Protein_catabolism of Ecm1 31 0.20 11.57 6.38
13 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
14 INT179810 Protein_catabolism of Ecm1 30 0.11 18.28 5.75
15 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
16 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
17 INT181022 Binding of Ccr1 15 0.37 10.69 5.37
18 INT166878 Regulation of Ccl3 9 0.44 8.21 4.81
19 INT150237 Localization of Ccr1 10 0.75 9.25 4.72
20 INT153269 Binding of Ccl3 10 0.48 8.87 4.69
21 INT102855 Negative_regulation of Srgn 8 0.57 0.91 4.63
22 INT134968 Localization of Ecm1 20 0.32 27.27 4.31
23 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
24 INT79234 Positive_regulation of CCL3 15 0.67 11.43 4.15
25 INT65700 Localization of CCR1 7 0.51 4 3.91
26 INT144083 Positive_regulation of Gene_expression of Ccl3 10 0.50 8.16 3.81
27 INT92678 Positive_regulation of Ecm1 30 0.09 28.41 3.68
28 INT132187 Gene_expression of Ecm1 14 0.21 8.12 3.52
29 INT181357 Negative_regulation of Ccl3 12 0.59 13.09 3.38
30 INT171233 Binding of Ecm1 25 0.07 12.41 3.36
31 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
32 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
33 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
34 INT102856 Positive_regulation of Srgn 7 0.61 1.27 2.54
35 INT71681 Positive_regulation of Gene_expression of CCL3 8 0.54 8.21 2.41
36 INT134964 Regulation of Ecm1 13 0.10 7.45 2.37
37 INT160080 Localization of Ecm1 6 0.15 4.86 2.36
38 INT23588 Positive_regulation of CCR1 6 0.67 4.44 2.24
39 INT181402 Negative_regulation of Ccr1 8 0.42 7 2.2
40 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
41 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
42 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93
43 INT120014 Transcription of CCL3 5 0.69 3.03 1.82
44 INT102857 Phosphorylation of Srgn 1 0.72 0.26 1.71
45 INT134965 Negative_regulation of Ecm1 7 0.18 7.86 1.7
46 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
47 INT180678 Negative_regulation of Protein_catabolism of Ecm1 6 0.08 2.69 1.61
48 INT118412 Gene_expression of Gata1 5 0.62 0.83 1.6
49 INT89849 Regulation of Srgn 6 0.30 0.93 1.59
50 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
51 INT118413 Positive_regulation of Gene_expression of Gata1 3 0.40 0.68 1.56
52 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
53 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
54 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
55 INT159102 Regulation of Ecm1 9 0.16 1.28 1.41
56 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
57 INT102852 Negative_regulation of Phosphorylation of Srgn 1 0.52 0.17 1.32
58 INT102853 Positive_regulation of Phosphorylation of Srgn 1 0.61 0.17 1.31
59 INT78692 Regulation of PTK2B 2 0.47 0.29 1.28
60 INT65699 Localization of CCL3 7 0.78 2.56 1.25
61 INT123828 Regulation of CCL3 3 0.60 0.79 1.25
62 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
63 INT105571 Gene_expression of SRGN 33 0.58 14.68 1.19
64 INT48338 Gene_expression of Ahsg 2 0.52 0.25 1.16
65 INT153267 Negative_regulation of Binding of Ccl3 2 0.43 2.06 1.14
66 INT268754 Negative_regulation of Gene_expression of Ccr1 5 0.43 2.76 1.13
67 INT181410 Regulation of Gene_expression of Ccl3 2 0.33 3.52 1.06
68 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
69 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04
70 INT180683 Positive_regulation of Protein_catabolism of Ecm1 9 0.09 2.25 1.03
71 INT166880 Negative_regulation of Gene_expression of Ccl3 1 0.57 0.81 1.01
72 INT89853 Gene_expression of Srgn 12 0.44 1.13 1
73 INT268753 Negative_regulation of Positive_regulation of Ccr1 1 0.42 2.59 0.96
74 INT166715 Gene_expression of Sox9 16 0.65 6.39 0.92
75 INT248774 Positive_regulation of Localization of Ecm1 4 0.05 8.46 0.92
76 INT147880 Regulation of SRGN 28 0.33 13.99 0.9
77 INT202174 Negative_regulation of CCL3 2 0.26 1.77 0.9
78 INT79235 Binding of CCL3 3 0.36 2.2 0.88
79 INT33495 Regulation of Ahsg 1 0.23 0 0.86
80 INT48339 Regulation of Localization of Ahsg 1 0.21 0 0.86
81 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85
82 INT179814 Positive_regulation of Protein_catabolism of Ecm1 5 0.06 3.38 0.85
83 INT48337 Localization of Ahsg 1 0.54 0 0.85
84 INT151907 Binding of Ecm1 6 0.11 2.48 0.83
85 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
86 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
87 INT145306 Gene_expression of Sox9 5 0.54 2.47 0.8
88 INT181359 Transcription of Ccr1 4 0.53 1.66 0.8
89 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
90 INT153272 Positive_regulation of Localization of Ccl3 2 0.50 2.02 0.79
91 INT268746 Positive_regulation of Binding of Ccr1 1 0.50 1.81 0.79
92 INT250847 Negative_regulation of Ecm1 1 0.03 1.72 0.78
93 INT130797 Gene_expression of Fgf23 6 0.66 4.73 0.77
94 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
95 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
96 INT120013 Negative_regulation of Transcription of CCL3 1 0.41 1 0.72
97 INT144995 Positive_regulation of Gata1 1 0.37 0.14 0.71
98 INT153270 Positive_regulation of Binding of Ccl3 1 0.47 1.44 0.69
99 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
100 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
101 INT171692 Regulation of Protein_catabolism of Ecm1 4 0.12 1.5 0.65
102 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
103 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
104 INT89363 Positive_regulation of Ahsg 2 0.11 1.11 0.63
105 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
106 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
107 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
108 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
109 INT117275 Localization of STATH 1 0.00 0 0.6
110 INT179337 Positive_regulation of Gene_expression of Ecm1 14 0.05 3.73 0.58
111 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
112 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
113 INT189481 Regulation of Gene_expression of Ccr1 3 0.45 1.97 0.58
114 INT110319 Positive_regulation of SRGN 10 0.40 6.2 0.56
115 INT172297 Binding of CCR1 1 0.36 0.08 0.56
116 INT171693 Positive_regulation of Ecm1 5 0.09 2.14 0.55
117 INT128360 Negative_regulation of Positive_regulation of Ccl3 2 0.41 1.86 0.55
118 INT97637 Positive_regulation of Localization of CCR1 1 0.08 0.51 0.55
119 INT132186 Negative_regulation of Gene_expression of Ecm1 2 0.06 1.73 0.54
120 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
121 INT221040 Negative_regulation of Gene_expression of CCL3 2 0.20 1.19 0.53
122 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
123 INT242208 Regulation of Gene_expression of SRGN 7 0.29 3.15 0.52
124 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
125 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
126 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
127 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
128 INT182225 Transcription of CCR1 1 0.57 0.45 0.47
129 INT145304 Regulation of Gene_expression of Sox9 1 0.43 1.04 0.46
130 INT250837 Positive_regulation of Negative_regulation of Ecm1 1 0.04 1.1 0.44
131 INT109920 Positive_regulation of PTK2B 5 0.43 2.21 0.43
132 INT205725 Regulation of Regulation of Ecm1 1 0.03 0.1 0.4
133 INT109922 Negative_regulation of PTK2B 3 0.26 1.63 0.39
134 INT268761 Positive_regulation of Positive_regulation of Ccr1 1 0.43 1.51 0.39
135 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
136 INT171023 Negative_regulation of Gene_expression of CCR1 2 0.37 1.53 0.36
137 INT89367 Negative_regulation of Ahsg 2 0.14 0.85 0.36
138 INT306349 Transcription of SRGN 1 0.20 2.36 0.36
139 INT109919 Positive_regulation of Positive_regulation of PTK2B 1 0.31 0.09 0.35
140 INT320784 Protein_catabolism of Hif1a 3 0.61 2.41 0.34
141 INT250834 Negative_regulation of Localization of Ecm1 1 0.04 0.58 0.34
142 INT247563 Negative_regulation of Positive_regulation of Hif1a 1 0.16 9.12 0.32
143 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29
144 INT173105 Transcription of HIF1A 6 0.67 4.47 0.28
145 INT130799 Localization of Fgf23 2 0.63 1.94 0.28
146 INT79236 Positive_regulation of Positive_regulation of CCL3 1 0.49 1.22 0.28
147 INT157409 Negative_regulation of Fgf23 3 0.50 3.21 0.27
148 INT232786 Positive_regulation of Localization of Hif1a 2 0.31 2.63 0.27
149 INT165579 Regulation of Gene_expression of Ahsg 1 0.01 0.25 0.26
150 INT165577 Positive_regulation of Gene_expression of Ahsg 1 0.04 0.25 0.26
151 INT343565 Positive_regulation of Gene_expression of Ecm1 1 0.07 0.94 0.25
152 INT171025 Negative_regulation of Localization of CCR1 1 0.37 0.4 0.25
153 INT254818 Positive_regulation of Positive_regulation of Ecm1 4 0.06 5.27 0.24
154 INT301314 Regulation of Binding of CCL3 1 0.04 0 0.24
155 INT268747 Positive_regulation of Localization of Ccr1 1 0.43 0.8 0.23
156 INT181399 Transcription of Ccl3 2 0.60 0.41 0.22
157 INT145303 Regulation of Sox9 2 0.28 0.71 0.22
158 INT245763 Regulation of SOX9 4 0.43 1.68 0.21
159 INT173103 Positive_regulation of Transcription of HIF1A 3 0.49 2.11 0.21
160 INT268750 Positive_regulation of Transcription of Ccr1 2 0.46 0.26 0.21
161 INT141306 Binding of Srgn 1 0.30 0.23 0.21
162 INT130798 Positive_regulation of Gene_expression of Fgf23 2 0.59 1.12 0.2
163 INT247564 Positive_regulation of Transcription of Hif1a 1 0.19 2.05 0.2
164 INT134662 Positive_regulation of Gene_expression of SOX9 9 0.48 1.69 0.19
165 INT89400 Phosphorylation of PTK2B 4 0.38 1.16 0.19
166 INT171231 Regulation of Binding of Ecm1 2 0.06 0.2 0.19
167 INT23591 Regulation of CCR1 1 0.26 0.96 0.19
168 INT268764 Regulation of Positive_regulation of Ccr1 1 0.45 0.83 0.18
169 INT89851 Localization of Srgn 1 0.58 0.15 0.18
170 INT181340 Negative_regulation of Negative_regulation of Ccr1 1 0.28 0.67 0.18
171 INT89850 Positive_regulation of Localization of Srgn 1 0.36 0.15 0.18
172 INT254804 Negative_regulation of Protein_catabolism of Ecm1 2 0.04 0.97 0.17
173 INT158243 Positive_regulation of Positive_regulation of CCR1 1 0.39 0.26 0.17
174 INT351417 Regulation of Protein_catabolism of Ecm1 1 0.00 0.98 0.17
175 INT158248 Negative_regulation of Positive_regulation of CCR1 1 0.36 0.26 0.17
176 INT329819 Phosphorylation of CCL3 1 0.23 0.61 0.17
177 INT285899 Positive_regulation of Localization of CCL3 1 0.12 1.08 0.17
178 INT89857 Regulation of Gene_expression of Srgn 1 0.20 0.17 0.17
179 INT180594 Localization of ECM1 1 0.07 0.5 0.17
180 INT142732 Negative_regulation of STATH 3 0.42 1.72 0.16
181 INT312718 Protein_catabolism of CCL3 1 0.31 0.44 0.16
182 INT118372 Regulation of Fgf23 4 0.55 3.31 0.15
183 INT249919 Regulation of Regulation of Hif1a 2 0.29 1.81 0.14
184 INT249908 Binding of Hif1a 2 0.31 1.48 0.14
185 INT220570 Transcription of Gata1 2 0.05 0.91 0.14
186 INT319407 Positive_regulation of Transcription of STATH 1 0.40 0.69 0.14
187 INT319441 Transcription of STATH 1 0.58 0.69 0.14
188 INT249913 Regulation of Gene_expression of Hif1a 2 0.32 1.82 0.13
189 INT89409 Negative_regulation of Phosphorylation of PTK2B 2 0.13 0.89 0.12
190 INT290471 Positive_regulation of Transcription of ECM1 1 0.04 1.56 0.12
191 INT290469 Transcription of ECM1 1 0.04 1.55 0.12
192 INT211949 Negative_regulation of Sox9 1 0.31 0.83 0.12
193 INT295974 Regulation of Fgf23 1 0.07 2.3 0.11
194 INT105392 Positive_regulation of Binding of HIF1A 5 0.45 3.83 0.1
195 INT171221 Regulation of Gene_expression of Ecm1 1 0.06 0.08 0.1
196 INT285555 Positive_regulation of Gene_expression of CCR1 1 0.16 1.11 0.1
197 INT218593 Regulation of Gene_expression of Ecm1 1 0.04 1.49 0.1
198 INT135555 Localization of PTK2B 1 0.57 0.32 0.1
199 INT153064 Positive_regulation of Regulation of Hif1a 1 0.45 1.52 0.1
200 INT184220 Negative_regulation of Gene_expression of SOX9 4 0.36 0.58 0.09
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