GO:0030507

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Name spectrin binding
Categary Function
Go Slim No
Go Link GO:0030507
Unique Molecular Interactions 22
Total Molecular Interactions 46
Total Single Events 183
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for spectrin binding. They are ordered first by their pain relevance and then by number of times they were reported for spectrin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63488 Sptan1 Positive_regulation of Rtcd1 1 0.03 0.34 0.91
2 INT52759 Oprd1 Regulation of Sptan1 1 0.03 0 0.9
3 INT52761 Dll1 Regulation of Sptan1 1 0.07 0 0.89
4 INT331675 Binding of Drd1a and Sptan1 1 0.03 0.33 0.4
5 INT238632 Binding of EPB41 and Cask 1 0.44 0.78 0.27
6 INT118127 Binding of STXBP3 and Stx4 1 0.01 0.24 0.15
7 INT214012 Binding of Ank1 and Nav1 1 0.01 0.51 0.1
8 INT214011 Negative_regulation of Binding of Ank1 and Nav1 1 0.01 0.51 0.1
9 INT257665 Binding of Nphs1 and Pard3 1 0.39 0.67 0.09
10 INT238631 Regulation of Binding of EPB41 and Cask 1 0.29 0.24 0.07
11 INT210827 Binding of EPB41 and TPM3 1 0.03 0.17 0.06
12 INT321402 Binding of NPHS1 and PIK3CD 1 0.02 0.73 0.03
13 INT257662 Binding of Mbp and Nphs1 1 0.11 0 0
14 INT262516 Binding of Sema6a and Sptan1 1 0.01 0.47 0
15 INT257663 Binding of Nck1 and Nphs1 1 0.09 0 0
16 INT263248 Binding of ADD1 and RAPGEF5 1 0.01 0.84 0
17 INT297688 Binding of Fut1 and Nphs1 1 0.03 0 0
18 INT257664 Regulation of Binding of Nphs1 and Pard3 1 0.36 0 0
19 INT304608 Binding of GYPA and Epb4.1 1 0.00 0.4 0
20 INT276587 Binding of Iqgap1 and Nphs1 1 0.08 0.33 0
21 INT238630 Negative_regulation of Binding of EPB41 and Cask 1 0.45 0 0
22 INT263249 Binding of ADD1 and REN 1 0.03 0.82 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for spectrin binding. They are ordered first by their pain relevance and then by number of times they were reported in spectrin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT47702 Gene_expression of Sptan1 24 0.76 7.6 11.36
2 INT52755 Positive_regulation of Sptan1 6 0.67 1.57 3.82
3 INT52756 Negative_regulation of Sptan1 7 0.42 1.31 3.19
4 INT54435 Binding of Sptan1 8 0.36 4.7 2.44
5 INT54433 Transcription of Sptan1 1 0.69 0 2.03
6 INT44784 Gene_expression of NPHS1 8 0.64 9.75 1.74
7 INT52758 Negative_regulation of Positive_regulation of Sptan1 2 0.57 0.33 1.73
8 INT129179 Gene_expression of Ank1 4 0.31 0.47 1.35
9 INT50389 Localization of Sptan1 3 0.73 0 1.16
10 INT80736 Protein_catabolism of Sptan1 5 0.32 3.32 1.1
11 INT71987 Regulation of Gene_expression of Sptan1 1 0.60 0 1.03
12 INT161882 Negative_regulation of Gene_expression of NPHS1 2 0.41 6.54 0.95
13 INT159986 Positive_regulation of Gene_expression of Sptan1 2 0.68 1.1 0.95
14 INT80737 Positive_regulation of Protein_catabolism of Sptan1 1 0.12 1.39 0.64
15 INT142419 Regulation of Sptan1 2 0.38 2.52 0.55
16 INT19581 Regulation of NPHS1 3 0.25 2.38 0.5
17 INT134588 Positive_regulation of Positive_regulation of Sptan1 1 0.49 0 0.41
18 INT19582 Binding of NPHS1 1 0.02 0.28 0.4
19 INT238585 Binding of EPB41 1 0.47 0.06 0.31
20 INT238584 Positive_regulation of Binding of EPB41 1 0.49 0 0.24
21 INT339443 Negative_regulation of Nphs1 1 0.16 1.24 0.23
22 INT210859 Gene_expression of EPB41 8 0.75 1.46 0.21
23 INT182647 Positive_regulation of EPB41 2 0.01 0.77 0.2
24 INT274516 Regulation of EPB41 1 0.01 0.14 0.12
25 INT274519 Protein_catabolism of EPB41 1 0.01 0.18 0.1
26 INT214008 Negative_regulation of Ank1 4 0.03 1.49 0.09
27 INT238505 Regulation of Gene_expression of NPHS1 1 0.29 2.93 0.06
28 INT257647 Localization of Nphs1 1 0.71 0.34 0.05
29 INT321416 Phosphorylation of NPHS1 1 0.12 1.5 0.05
30 INT159766 Positive_regulation of Ank1 1 0.07 0.1 0.04
31 INT257641 Binding of Nphs1 1 0.46 0.33 0.04
32 INT208887 Regulation of Ank1 1 0.01 0.08 0.04
33 INT354957 Binding of Ank1 1 0.02 0 0.04
34 INT321427 Negative_regulation of Phosphorylation of NPHS1 1 0.07 0.79 0.03
35 INT321418 Negative_regulation of NPHS1 1 0.07 0.79 0.03
36 INT257642 Gene_expression of Nphs1 4 0.66 0.96 0
37 INT257638 Positive_regulation of Nphs1 1 0.66 0.22 0
38 INT271551 Localization of Ank1 1 0.03 0.11 0
39 INT257644 Positive_regulation of Gene_expression of Nphs1 1 0.48 0 0
40 INT257643 Regulation of Nphs1 1 0.26 0.62 0
41 INT263252 Negative_regulation of ADD1 1 0.04 0.27 0
42 INT238583 Regulation of Binding of EPB41 1 0.44 0 0
43 INT257651 Regulation of Binding of Nphs1 1 0.43 0 0
44 INT257633 Positive_regulation of Binding of Nphs1 1 0.66 0 0
45 INT263253 Positive_regulation of ADD1 1 0.11 0.83 0
46 INT321735 Negative_regulation of Epb4.1 1 0.42 0.07 0
47 INT274520 Regulation of Positive_regulation of EPB41 1 0.01 0 0
48 INT274518 Positive_regulation of Positive_regulation of EPB41 1 0.01 0 0
49 INT257637 Negative_regulation of Positive_regulation of Nphs1 1 0.41 0 0
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