GO:0030511

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Name positive regulation of transforming growth factor beta receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0030511
Unique Molecular Interactions 187
Total Molecular Interactions 278
Total Single Events 1050
Pain Genes Associated 29

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of transforming growth factor beta receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of transforming growth factor beta receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT317526 Binding of Hint1 and Gipc1 1 0.00 0.25 2.38
2 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
3 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
4 INT117341 ADAM17 Positive_regulation of EGFR 1 0.16 3.56 0.82
5 INT102162 Binding of TNF and Adam17 1 0.14 0.88 0.78
6 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
7 INT4915 Binding of Tac2 and Gipc1 1 0.01 0 0.74
8 INT104301 Adam17 Regulation of Negative_regulation of Sell 1 0.39 0.58 0.69
9 INT281083 Binding of Gria1 and Gipc1 1 0.01 0 0.65
10 INT111184 Binding of GIPC1 and CHCHD8 1 0.00 0 0.59
11 INT77394 Binding of ARRB1 and GIPC1 1 0.01 0 0.56
12 INT192160 Cxcl9 Negative_regulation of Furin 1 0.02 0.8 0.54
13 INT192162 Furin Positive_regulation of Mmp14 1 0.10 0.79 0.53
14 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
15 INT150796 ZNF398 Positive_regulation of THBS1 1 0.06 0.5 0.52
16 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
17 INT130930 Egr1 Negative_regulation of Positive_regulation of Thbs1 1 0.58 0.64 0.38
18 INT285570 Binding of IL8 and Cdkn1c 1 0.11 0.76 0.34
19 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
20 INT117589 Binding of C5AR1 and GIPC1 1 0.10 0.39 0.34
21 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
22 INT80304 Nrd1 Negative_regulation of Furin 1 0.01 0 0.3
23 INT203733 Thbs1 Positive_regulation of Negative_regulation of Ppara 1 0.36 1.55 0.26
24 INT235013 Binding of DSG1 and Adam17 1 0.07 1.34 0.26
25 INT234980 Positive_regulation of Egfr Positive_regulation of Adam17 1 0.09 1.33 0.26
26 INT252356 Binding of THBS1 and Cd47 1 0.00 0.44 0.24
27 INT210785 Cdkn1c Positive_regulation of Itgbl1 1 0.38 0 0.23
28 INT187486 Binding of Prkag1 and Stk11 1 0.01 0.95 0.22
29 INT252357 Binding of THBS1 and Cd36 2 0.01 2.4 0.21
30 INT317394 Binding of Stk11 and Amp1 1 0.04 0.89 0.21
31 INT115142 TGM7 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
32 INT337260 ELL Positive_regulation of Gene_expression of THBS1 1 0.11 0.82 0.18
33 INT337263 ELL Regulation of Gene_expression of THBS1 1 0.10 0.82 0.18
34 INT333449 Binding of SMAD2 and SMAD4 1 0.23 0 0.17
35 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
36 INT231677 Binding of CD47 and THBS1 1 0.18 0 0.16
37 INT252352 Binding of THBS1 and Sirpa 1 0.00 0.26 0.15
38 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14
39 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
40 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
41 INT81789 Binding of MC1R and GIPC1 1 0.01 0 0.13
42 INT81786 Binding of AGRP and GIPC1 1 0.01 0 0.13
43 INT351974 Agt Positive_regulation of Gene_expression of Stk11 1 0.51 11.1 0.12
44 INT172976 Mras Regulation of Gene_expression of Smad4 1 0.00 0.83 0.12
45 INT259629 Binding of Adam17 and Timp3 1 0.01 0.19 0.11
46 INT189559 STK11 Positive_regulation of SNRK 1 0.03 0.36 0.11
47 INT294439 KLK4 Negative_regulation of THBS1 1 0.01 0 0.1
48 INT317392 Negative_regulation of Binding of Stk11 and Amp1 1 0.05 0.34 0.1
49 INT348167 Thbs1 Positive_regulation of RAC1 1 0.04 0.71 0.08
50 INT302178 CDKN1C Regulation of CDKN2A 1 0.09 0.26 0.08
51 INT353070 ADAM17 Positive_regulation of TNF 1 0.19 1.66 0.08
52 INT210790 Ihh Negative_regulation of Cdkn1c 1 0.30 0 0.08
53 INT245118 RBM45 Negative_regulation of CDKN2B 1 0.01 1.41 0.08
54 INT245119 Negative_regulation of RBM45 Negative_regulation of CDKN2B 1 0.01 1.43 0.08
55 INT317398 Amp1 Positive_regulation of Phosphorylation of Stk11 1 0.05 0.22 0.07
56 INT317391 Amp1 Positive_regulation of Stk11 1 0.05 0.22 0.07
57 INT348168 Thbs1 Positive_regulation of PIK3CD 1 0.00 0.65 0.07
58 INT253139 Il6 Positive_regulation of Phosphorylation of Stk11 1 0.26 0.34 0.07
59 INT311906 Binding of Smad4 and Insrr 1 0.00 0.18 0.06
60 INT317389 Binding of Prkag1 and Stk11 1 0.16 0.2 0.06
61 INT317397 Negative_regulation of Binding of Prkag1 and Stk11 1 0.19 0.2 0.06
62 INT203732 Thbs1 Regulation of Gene_expression of Ppara 1 0.33 0.94 0.05
63 INT302176 CDKN1C Regulation of CDKN1A 1 0.09 0.26 0.05
64 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05
65 INT341535 F2RL1 Positive_regulation of Gene_expression of THBS1 1 0.28 0.75 0.04
66 INT353290 Binding of Smad2 and Smad4 1 0.20 0.08 0.04
67 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
68 INT270950 Binding of Slc6a3 and Tgfb1i1 1 0.02 0.23 0.04
69 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
70 INT129331 Binding of Trpv1 and Gipc1 1 0.01 0 0.03
71 INT317388 Stk11 Regulation of Positive_regulation of Prkag1 1 0.23 0.11 0.03
72 INT280263 Binding of Smad4 and Proc 1 0.00 1.26 0.03
73 INT317404 Acc Positive_regulation of Stk11 1 0.41 0.06 0.03
74 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03
75 INT277927 WIF1 Negative_regulation of SMAD4 1 0.23 0.37 0
76 INT197808 Binding of MEN1 and NME1 1 0.00 1.81 0
77 INT314869 Binding of Gdf11 and Tgfbr3 1 0.29 0.14 0
78 INT351972 Binding of Agt and Stk11 1 0.27 0.74 0
79 INT197809 Binding of MEN1 and VIM 1 0.04 0.52 0
80 INT269932 Pcna Negative_regulation of Cdkn2b 1 0.09 0.07 0
81 INT324058 Fn1 Positive_regulation of Furin 1 0.08 0.27 0
82 INT285666 PPARA Positive_regulation of TGFB1I1 1 0.15 0.82 0
83 INT215686 Cdkn2b Negative_regulation of Cdkn1c 1 0.01 0 0
84 INT197810 Binding of MEN1 and MUC1 1 0.06 0.47 0
85 INT337270 E2F1 Positive_regulation of Transcription of THBS1 1 0.67 0.19 0
86 INT337268 E2F1 Regulation of Transcription of THBS1 1 0.44 0 0
87 INT337274 E2F1 Regulation of THBS1 1 0.44 0 0
88 INT314871 Binding of Tgfbr3 and Atoh7 1 0.33 0.09 0
89 INT99770 Thbs1 Regulation of PGR 1 0.01 0 0
90 INT337269 Binding of E2F1 and Positive_regulation of Gene_expression of THBS1 1 0.45 0.21 0
91 INT324056 Binding of Itk and Furin 1 0.03 0.48 0
92 INT197816 Binding of MEN1 and NFKB1 1 0.05 0.07 0
93 INT197813 Binding of AMBP and MEN1 1 0.00 0.51 0
94 INT337262 PRB1 Negative_regulation of THBS1 1 0.18 0.61 0
95 INT107434 Negative_regulation of Tgfb1i1 Positive_regulation of Cxcl2 1 0.01 0 0
96 INT351975 Agt Positive_regulation of Stk11 1 0.34 0.39 0
97 INT269924 Smad3 Regulation of Gene_expression of Cdkn2b 1 0.23 0.26 0
98 INT269926 Cdkn2b Negative_regulation of Pcna 1 0.08 0.07 0
99 INT262750 GLYR1 Positive_regulation of THBS1 1 0.01 0.99 0
100 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
101 INT215700 Binding of Cdkn2b and Cdk6 1 0.02 0 0
102 INT99769 Thbs1 Regulation of THBS1 1 0.00 0 0
103 INT277490 Binding of F2 and Thbs1 1 0.09 0 0
104 INT215690 Binding of Cdk6 and Cdkn1c 1 0.03 0 0
105 INT337264 Binding of E2F1 and THBS1 1 0.47 0.78 0
106 INT268524 MYC Regulation of THBS1 1 0.02 1.85 0
107 INT337273 E2F1 Regulation of Gene_expression of THBS1 1 0.60 0 0
108 INT269936 Smad2 Positive_regulation of Cdkn2b 1 0.15 0.07 0
109 INT351984 Gene_expression of Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.8 0
110 INT268341 SMAD2 Positive_regulation of SMAD4 1 0.31 0.56 0
111 INT197817 Binding of JUND and MEN1 1 0.18 0.14 0
112 INT236724 Binding of AXIN1 and Ctnnd2 1 0.39 1.03 0
113 INT269950 Sox17 Negative_regulation of Gene_expression of Cdkn2b 1 0.27 0.24 0
114 INT351982 Smarca4 Positive_regulation of Stk11 1 0.05 0.58 0
115 INT337266 E2F1 Positive_regulation of Gene_expression of THBS1 1 0.67 0.21 0
116 INT99772 Pgr Regulation of THBS1 1 0.00 0 0
117 INT215699 Cdkn2a Negative_regulation of Cdkn1c 1 0.01 0 0
118 INT253020 Pttg1 Negative_regulation of THBS1 1 0.03 0.16 0
119 INT197844 Binding of MEN1 and Nfkb1 1 0.06 0.26 0
120 INT107438 Tgfb1i1 Positive_regulation of Tnf 1 0.00 0 0
121 INT285396 Binding of Adam17 and R3hcc1 1 0.15 0.93 0
122 INT107435 Tgfb1i1 Positive_regulation of Gene_expression of Tnf 1 0.00 0 0
123 INT277489 Binding of Thbs1 and Gopc 1 0.14 0 0
124 INT246797 Tgfb1i1 Positive_regulation of Phosphorylation of Tsc2 1 0.01 0.66 0
125 INT269929 Binding of Cdkn2b and Smad3 1 0.18 0.89 0
126 INT337265 Negative_regulation of E2F1 Positive_regulation of THBS1 1 0.42 0 0
127 INT351985 Stk11 Positive_regulation of Gene_expression of Dcc 1 0.01 1.79 0
128 INT337272 E2F1 Positive_regulation of THBS1 1 0.49 1.27 0
129 INT337267 THBS1 Positive_regulation of E2F1 1 0.49 0.05 0
130 INT351976 Binding of Tp53 and Stk11 1 0.13 2.3 0
131 INT99771 Oxtr Regulation of THBS1 1 0.01 0 0
132 INT284915 Binding of CDKN2B and HIST2H3C 1 0.05 0.43 0
133 INT151589 Stk11 Positive_regulation of Prkag1 1 0.41 0.17 0
134 INT184461 Binding of Adamts1 and Furin 1 0.09 0 0
135 INT215695 Lamtor1 Negative_regulation of Cdkn1c 1 0.02 0 0
136 INT197815 Binding of MEN1 and TGFB1 1 0.16 0.13 0
137 INT215688 Cdkn2b Negative_regulation of Kras 1 0.00 0 0
138 INT215704 Stmn1 Negative_regulation of Cdkn1c 1 0.00 0 0
139 INT215694 Cdkn2b Negative_regulation of Cdkn1b 1 0.01 0 0
140 INT246785 Tgfb1i1 Positive_regulation of Positive_regulation of Akt1 1 0.01 0.66 0
141 INT259094 STK11 Positive_regulation of Gene_expression of TCEAL1 1 0.18 5.5 0
142 INT107437 Tgfb1i1 Positive_regulation of Cxcl2 1 0.01 0 0
143 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0
144 INT172981 PAN3 Negative_regulation of SMAD4 1 0.01 0.98 0
145 INT197814 Binding of MEN1 and RELA 1 0.42 0.07 0
146 INT314853 Binding of Cdc7 and Tgfbr3 1 0.24 0.09 0
147 INT268511 MIR19B1 Regulation of THBS1 1 0.20 0.35 0
148 INT107436 Tgfb1i1 Positive_regulation of Gene_expression of Cxcl2 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of transforming growth factor beta receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of transforming growth factor beta receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117142 Gene_expression of Thbs1 58 0.72 45.02 6.51
2 INT130875 Gene_expression of ADAM17 13 0.78 15.46 6.41
3 INT104299 Negative_regulation of Adam17 18 0.47 12.03 4.39
4 INT102157 Gene_expression of Adam17 3 0.58 4.17 2.86
5 INT211733 Phosphorylation of Gipc1 2 0.01 0 2.68
6 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
7 INT161978 Positive_regulation of Localization of GIPC1 1 0.19 1.98 2.12
8 INT130364 Positive_regulation of Thbs1 7 0.62 7.73 1.97
9 INT161979 Positive_regulation of Gene_expression of GIPC1 1 0.19 1.96 1.93
10 INT107178 Gene_expression of Smad4 12 0.65 9.85 1.92
11 INT117346 Positive_regulation of ADAM17 5 0.50 6.69 1.86
12 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
13 INT130874 Negative_regulation of Gene_expression of ADAM17 3 0.43 5.03 1.76
14 INT42277 Gene_expression of GIPC1 6 0.25 2.06 1.61
15 INT130332 Gene_expression of Adam17 14 0.50 4.84 1.56
16 INT53673 Gene_expression of Furin 6 0.40 1.99 1.54
17 INT111186 Positive_regulation of GIPC1 4 0.67 1.44 1.46
18 INT78861 Negative_regulation of Transcription of Adam17 2 0.29 1.4 1.32
19 INT78859 Transcription of Adam17 2 0.47 1.39 1.31
20 INT288546 Regulation of Positive_regulation of THBS1 1 0.36 2.65 1.27
21 INT53666 Regulation of Furin 4 0.37 0.3 1.24
22 INT150805 Localization of THBS1 4 0.46 2.88 1.23
23 INT234893 Positive_regulation of Adam17 4 0.38 3.78 1.22
24 INT93625 Gene_expression of Cdkn1c 2 0.75 0.42 1.2
25 INT203729 Binding of Thbs1 1 0.27 3.83 1.1
26 INT130928 Positive_regulation of Gene_expression of Thbs1 7 0.62 5.62 1.08
27 INT99767 Regulation of THBS1 18 0.42 11.51 1.03
28 INT132435 Negative_regulation of ADAM17 2 0.50 3.75 1.02
29 INT59995 Localization of GIPC1 2 0.28 0.66 0.87
30 INT53669 Regulation of Transcription of Furin 1 0.16 0.15 0.82
31 INT53670 Transcription of Furin 3 0.50 0.39 0.81
32 INT93621 Positive_regulation of Gene_expression of Cdkn1c 1 0.67 0.42 0.77
33 INT130363 Localization of Thbs1 9 0.75 4.99 0.76
34 INT27546 Positive_regulation of Furin 4 0.40 0.49 0.75
35 INT27545 Gene_expression of Furin 6 0.63 0.75 0.74
36 INT172960 Negative_regulation of Gene_expression of Smad4 7 0.39 5.88 0.71
37 INT27742 Negative_regulation of Furin 2 0.17 0.22 0.64
38 INT197832 Localization of MEN1 1 0.80 11.01 0.63
39 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59
40 INT117145 Negative_regulation of Gene_expression of Thbs1 11 0.43 5.67 0.57
41 INT138678 Transcription of ADAM17 1 0.69 4.9 0.56
42 INT77397 Phosphorylation of GIPC1 1 0.01 0 0.56
43 INT103781 Negative_regulation of Smad4 9 0.42 4.42 0.54
44 INT192154 Negative_regulation of Furin 2 0.22 0.94 0.53
45 INT150808 Negative_regulation of Localization of THBS1 1 0.25 0.5 0.53
46 INT253108 Phosphorylation of Stk11 4 0.65 2.13 0.52
47 INT100191 Gene_expression of Cdkn2b 1 0.65 0.06 0.51
48 INT138676 Localization of ADAM17 4 0.73 4.91 0.5
49 INT52920 Phosphorylation of Gipc1 1 0.04 0 0.5
50 INT267837 Gene_expression of TGFB1I1 1 0.15 1.38 0.48
51 INT268576 Positive_regulation of Gene_expression of THBS1 2 0.64 2.26 0.47
52 INT210125 Regulation of Axin1 1 0.02 2.45 0.46
53 INT90764 Positive_regulation of Furin 4 0.32 1.7 0.44
54 INT61102 Gene_expression of MEN1 12 0.78 17.7 0.43
55 INT71019 Negative_regulation of SMAD4 12 0.42 6.88 0.43
56 INT203728 Regulation of Binding of Thbs1 1 0.33 2.76 0.42
57 INT203726 Regulation of Thbs1 2 0.33 1.41 0.41
58 INT251556 Localization of Adam17 2 0.38 2 0.39
59 INT46545 Binding of Gipc1 2 0.02 0 0.38
60 INT117564 Gene_expression of SMAD4 12 0.71 8.7 0.37
61 INT225223 Localization of Cdkn2b 2 0.62 1.29 0.37
62 INT130927 Negative_regulation of Thbs1 19 0.59 3.72 0.36
63 INT119612 Positive_regulation of Gipc1 1 0.01 0 0.35
64 INT351970 Gene_expression of Stk11 1 0.75 33.89 0.35
65 INT285500 Binding of Cdkn1c 1 0.18 0.76 0.34
66 INT78862 Negative_regulation of Adam17 3 0.36 1.76 0.32
67 INT92100 Binding of Smad4 5 0.31 2.23 0.3
68 INT196426 Gene_expression of Cdkn2b 6 0.67 4.29 0.29
69 INT187284 Positive_regulation of Gene_expression of Adam17 3 0.20 1.32 0.29
70 INT203616 Positive_regulation of CDKN1C 2 0.60 12.62 0.27
71 INT42278 Binding of GIPC1 3 0.03 0.33 0.26
72 INT123541 Regulation of Gene_expression of Cdkn2b 1 0.26 0.06 0.26
73 INT164728 Positive_regulation of Cdkn1c 1 0.36 0.3 0.26
74 INT180101 Phosphorylation of Adam17 3 0.37 0.25 0.24
75 INT248401 Gene_expression of CDKN1C 21 0.67 14.52 0.23
76 INT130368 Transcription of Thbs1 2 0.69 1.39 0.23
77 INT78865 Localization of Adam17 1 0.43 0.34 0.23
78 INT130360 Positive_regulation of Transcription of Thbs1 1 0.46 1.41 0.23
79 INT80306 Localization of Furin 1 0.08 0 0.21
80 INT222635 Gene_expression of Thbs1 4 0.39 15.2 0.2
81 INT59961 Localization of Furin 3 0.76 2.21 0.2
82 INT115160 Gene_expression of CITED2 1 0.04 0.45 0.2
83 INT115153 Positive_regulation of Gene_expression of CITED2 1 0.02 0.45 0.2
84 INT178504 Positive_regulation of Localization of THBS1 2 0.05 1.9 0.19
85 INT351969 Positive_regulation of Gene_expression of Stk11 1 0.67 21.03 0.19
86 INT277935 Binding of SMAD4 4 0.28 1.12 0.17
87 INT248400 Regulation of CDKN1C 1 0.45 2.92 0.17
88 INT210123 Localization of Axin1 1 0.04 0.84 0.17
89 INT66933 Binding of AXIN1 6 0.32 1.8 0.16
90 INT231474 Binding of THBS1 4 0.34 2.04 0.16
91 INT138679 Regulation of ADAM17 1 0.19 1.13 0.16
92 INT138680 Binding of ADAM17 1 0.36 1.42 0.16
93 INT196603 Gene_expression of STK11 5 0.55 6.75 0.15
94 INT348150 Binding of Thbs1 1 0.24 2.06 0.15
95 INT139977 Regulation of Smad4 1 0.16 1.41 0.15
96 INT189633 Regulation of STK11 3 0.41 3.57 0.14
97 INT248403 Positive_regulation of Gene_expression of CDKN1C 1 0.40 7.77 0.14
98 INT263410 Negative_regulation of Axin1 1 0.01 0 0.14
99 INT106227 Binding of STK11 3 0.42 3.13 0.13
100 INT189583 Transcription of STK11 2 0.49 4.43 0.13
101 INT330233 Positive_regulation of Stk11 2 0.67 8.15 0.13
102 INT169349 Regulation of Adam17 1 0.37 0.97 0.13
103 INT151587 Positive_regulation of Stk11 2 0.38 0.44 0.12
104 INT348149 Regulation of Gene_expression of Thbs1 1 0.31 1.94 0.1
105 INT138677 Negative_regulation of Transcription of ADAM17 1 0.42 1.18 0.1
106 INT348145 Localization of Thbs1 1 0.41 6.72 0.1
107 INT184448 Binding of Furin 2 0.36 0.81 0.09
108 INT40116 Regulation of Gipc1 1 0.01 0 0.09
109 INT187285 Protein_catabolism of Adam17 1 0.12 0.94 0.09
110 INT253928 Negative_regulation of Binding of Furin 1 0.41 0.82 0.09
111 INT325510 Transcription of Smad4 1 0.67 0.16 0.09
112 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08
113 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08
114 INT356064 Regulation of Negative_regulation of Adam17 1 0.23 0.24 0.08
115 INT210778 Negative_regulation of Cdkn1c 1 0.36 0 0.08
116 INT356054 Regulation of Phosphorylation of Adam17 1 0.20 0.25 0.08
117 INT180096 Positive_regulation of Phosphorylation of Adam17 1 0.07 0 0.08
118 INT263690 Negative_regulation of Gipc1 1 0.01 0 0.08
119 INT245123 Gene_expression of CDKN2B 6 0.68 3.62 0.07
120 INT184989 Positive_regulation of CDKN2B 3 0.47 2.77 0.07
121 INT185030 Binding of CDKN2B 3 0.35 2.6 0.07
122 INT222588 Negative_regulation of Gene_expression of Thbs1 2 0.30 7.93 0.07
123 INT253107 Regulation of Stk11 2 0.33 0.3 0.07
124 INT253102 Negative_regulation of Stk11 1 0.31 0.22 0.07
125 INT197836 Positive_regulation of Gene_expression of MEN1 1 0.50 3.16 0.07
126 INT254790 Localization of Smad4 2 0.37 0.54 0.06
127 INT197828 Negative_regulation of MEN1 1 0.43 5.06 0.06
128 INT180094 Binding of Adam17 1 0.06 0 0.05
129 INT272847 Binding of Furin 1 0.04 0.52 0.05
130 INT330228 Phosphorylation of Stk11 1 0.18 0.27 0.05
131 INT244699 Positive_regulation of AXIN1 1 0.02 0 0.05
132 INT330227 Positive_regulation of Positive_regulation of Stk11 1 0.11 0.06 0.05
133 INT222624 Negative_regulation of Thbs1 2 0.30 8.42 0.04
134 INT99763 Regulation of Thbs1 2 0.23 2.08 0.04
135 INT351967 Negative_regulation of Gene_expression of Stk11 1 0.57 0.89 0.04
136 INT348152 Positive_regulation of Localization of Thbs1 1 0.24 0.85 0.04
137 INT348157 Regulation of Transcription of Thbs1 1 0.14 0.96 0.04
138 INT348147 Transcription of Thbs1 1 0.27 0.96 0.04
139 INT270964 Binding of Tgfb1i1 1 0.02 0.23 0.04
140 INT334291 Positive_regulation of Gene_expression of SMAD4 1 0.18 0 0.04
141 INT246285 Gene_expression of Cdkn1c 1 0.03 0.43 0.04
142 INT351966 Binding of Stk11 1 0.36 2.15 0.04
143 INT268360 Positive_regulation of SMAD4 3 0.55 1.55 0.03
144 INT294469 Transcription of THBS1 2 0.66 0.46 0.03
145 INT253104 Gene_expression of Stk11 2 0.53 0.07 0.03
146 INT289614 Positive_regulation of CITED2 1 0.37 0.41 0.03
147 INT203619 Positive_regulation of Positive_regulation of CDKN1C 1 0.13 0.34 0.03
148 INT231690 Negative_regulation of Binding of THBS1 1 0.16 0.37 0.03
149 INT317354 Regulation of Phosphorylation of Stk11 1 0.36 0.12 0.03
150 INT314842 Phosphorylation of Cdkn2b 1 0.71 0.61 0.03
151 INT283688 Transcription of Cdkn2b 1 0.28 0.11 0.03
152 INT117563 Negative_regulation of Gene_expression of SMAD4 6 0.54 3.87 0
153 INT284972 Negative_regulation of CDKN2B 3 0.44 1.13 0
154 INT248399 Negative_regulation of CDKN1C 2 0.37 2.71 0
155 INT196419 Negative_regulation of Cdkn2b 2 0.12 0.55 0
156 INT196429 Negative_regulation of Gene_expression of Cdkn2b 2 0.27 0.8 0
157 INT334327 Regulation of SMAD4 2 0.35 1.73 0
158 INT294025 Phosphorylation of AXIN1 2 0.38 0.47 0
159 INT259109 Negative_regulation of STK11 2 0.54 2.11 0
160 INT284937 Negative_regulation of Positive_regulation of CDKN2B 1 0.37 0.31 0
161 INT268368 Transcription of SMAD4 1 0.54 1.7 0
162 INT337281 Regulation of Gene_expression of THBS1 1 0.57 0.48 0
163 INT285684 Positive_regulation of Transcription of TGFB1I1 1 0.11 0.41 0
164 INT269911 Positive_regulation of Cdkn2b 1 0.31 0 0
165 INT277482 Negative_regulation of Transcription of Thbs1 1 0.43 0 0
166 INT287932 Negative_regulation of Binding of AXIN1 1 0.12 0 0
167 INT179300 Negative_regulation of TGFB1I1 1 0.06 1.92 0
168 INT252974 Positive_regulation of Negative_regulation of THBS1 1 0.03 0.09 0
169 INT171687 Positive_regulation of Gene_expression of Furin 1 0.28 0.42 0
170 INT348156 Positive_regulation of Gene_expression of Thbs1 1 0.24 0.9 0
171 INT197841 Positive_regulation of MEN1 1 0.41 2.38 0
172 INT351968 Negative_regulation of Stk11 1 0.42 4.84 0
173 INT173000 Negative_regulation of Localization of SMAD4 1 0.22 0.98 0
174 INT173008 Localization of SMAD4 1 0.38 0.97 0
175 INT228789 Positive_regulation of Negative_regulation of Thbs1 1 0.26 0.07 0
176 INT197843 Regulation of Localization of MEN1 1 0.45 0.24 0
177 INT351971 Regulation of Stk11 1 0.26 0.43 0
178 INT197838 Transcription of MEN1 1 0.69 0.13 0
179 INT246775 Positive_regulation of Tgfb1i1 1 0.01 0.21 0
180 INT313601 Regulation of CITED2 1 0.00 0.8 0
181 INT175049 Gene_expression of Gipc1 1 0.07 0.07 0
182 INT348146 Positive_regulation of Thbs1 1 0.25 2.41 0
183 INT277481 Negative_regulation of Negative_regulation of Thbs1 1 0.59 0 0
184 INT252970 Negative_regulation of Positive_regulation of THBS1 1 0.04 0.2 0
185 INT317352 Positive_regulation of Phosphorylation of Stk11 1 0.32 0 0
186 INT348158 Negative_regulation of Positive_regulation of Thbs1 1 0.22 0.65 0
187 INT284941 Transcription of CDKN2B 1 0.63 1.59 0
188 INT334289 Regulation of Binding of SMAD4 1 0.16 0 0
189 INT314839 Binding of Tgfbr3 1 0.42 0.09 0
190 INT334288 Regulation of Negative_regulation of SMAD4 1 0.16 0 0
191 INT242091 Phosphorylation of STK11 1 0.30 1.93 0
192 INT207312 Phosphorylation of THBS1 1 0.43 0.28 0
193 INT284970 Positive_regulation of Gene_expression of CDKN2B 1 0.61 0.55 0
194 INT301374 Localization of Stk11 1 0.23 1.58 0
195 INT285682 Transcription of TGFB1I1 1 0.15 0.4 0
196 INT248402 Negative_regulation of Positive_regulation of CDKN1C 1 0.37 1.04 0
197 INT269886 Binding of Cdkn2b 1 0.23 0.2 0
198 INT147085 Binding of Cdkn2b 1 0.10 0.07 0
199 INT277486 Negative_regulation of Positive_regulation of Thbs1 1 0.43 0 0
200 INT337279 Positive_regulation of Binding of THBS1 1 0.46 0 0
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