GO:0030512

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Name negative regulation of transforming growth factor beta receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0030512
Unique Molecular Interactions 442
Total Molecular Interactions 528
Total Single Events 3857
Pain Genes Associated 40

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transforming growth factor beta receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of transforming growth factor beta receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
3 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
4 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
5 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
6 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
7 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
8 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57
9 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
10 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
11 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
12 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
13 INT68157 Alox5 Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.13
14 INT68154 Mthfs Positive_regulation of Pdpk1 1 0.01 0.63 1.12
15 INT68158 Pla2g1b Positive_regulation of Pdpk1 1 0.05 0.63 1.12
16 INT68159 Pla2g1b Positive_regulation of Positive_regulation of Pdpk1 1 0.05 0.64 1.12
17 INT68163 Mthfs Positive_regulation of Positive_regulation of Pdpk1 1 0.01 0.64 1.12
18 INT68165 Alox5 Positive_regulation of Pdpk1 1 0.01 0.63 1.12
19 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
20 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
21 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
22 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
23 INT107335 Pdpk1 Positive_regulation of Regulation of Sigmar1 1 0.02 0 0.93
24 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
25 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
26 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
27 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
28 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
29 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
30 INT69084 Binding of Adrb1 and Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.08 0.83
31 INT65807 Nr3c1 Positive_regulation of Cyp3a23/3a1 1 0.14 0 0.82
32 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78
33 INT110130 NR3C1 Regulation of ADORA1 1 0.04 0.73 0.77
34 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
35 INT317560 Binding of Pdpk1 and Pik3r1 1 0.13 0 0.65
36 INT32719 ENG Regulation of LH 2 0.00 0 0.64
37 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63
38 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
39 INT52820 Oprd1 Regulation of NR3C1 1 0.02 0.17 0.61
40 INT134214 CRH Regulation of Localization of ENG 1 0.14 0.39 0.53
41 INT5631 Ubqln1 Positive_regulation of Pdpk1 1 0.05 0 0.53
42 INT32151 ENG Positive_regulation of Gene_expression of IFNA1 1 0.37 0 0.53
43 INT32291 ENG Negative_regulation of LH 2 0.00 0 0.52
44 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
45 INT30618 Slc3a1 Regulation of ENG 1 0.00 0 0.5
46 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5
47 INT132242 NR3C1 Regulation of Gene_expression of Slc1a1 1 0.09 0.62 0.49
48 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
49 INT60872 Binding of ENG and Abat 1 0.00 0 0.49
50 INT60871 ENG Regulation of Localization of LH 1 0.00 0 0.49
51 INT259180 Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
52 INT259181 Phosphorylation of Pdpk1 Positive_regulation of Gene_expression of Gria1 1 0.02 0.4 0.49
53 INT352031 Binding of NR3C1 and JUND 1 0.10 2.87 0.48
54 INT141729 NR3C1 Regulation of Positive_regulation of Cnr1 1 0.06 0.7 0.47
55 INT43695 ENG Regulation of Regulation of Prl 1 0.00 0 0.47
56 INT60870 ENG Negative_regulation of Localization of LH 1 0.00 0 0.47
57 INT102213 Binding of ENG and HP 1 0.01 0 0.47
58 INT95469 P2ry6 Positive_regulation of Positive_regulation of Pdpk1 1 0.15 0 0.46
59 INT169478 TGFB3 Positive_regulation of Tgfa 1 0.01 0.9 0.44
60 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
61 INT15024 Prkcg Regulation of Pdpk1 1 0.09 0 0.43
62 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
63 INT169465 TGFB3 Positive_regulation of MTG1 1 0.03 0.89 0.43
64 INT151184 Pdpk1 Positive_regulation of Trpv1 1 0.08 0 0.42
65 INT151183 Pdpk1 Positive_regulation of Phosphorylation of Trpv1 1 0.08 0 0.42
66 INT202516 Positive_regulation of Binding of ENG and Penk 1 0.03 0.58 0.42
67 INT228055 WNT1 Positive_regulation of CTNND2 1 0.54 1.75 0.42
68 INT202515 Binding of ENG and Penk 1 0.02 0.57 0.41
69 INT32720 Negative_regulation of ENG Regulation of LH 1 0.00 0 0.41
70 INT227566 NR3C1 Positive_regulation of RS1 1 0.01 0 0.4
71 INT227568 NR3C1 Positive_regulation of HTR1A 1 0.00 0 0.4
72 INT13077 Tac2 Positive_regulation of NKX2-1 1 0.00 0 0.39
73 INT236111 Binding of Pdpk1 and Ppara 1 0.26 1.21 0.39
74 INT340297 Ea1 Positive_regulation of Negative_regulation of Peg10 1 0.00 0 0.39
75 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
76 INT73772 NR3C1 Regulation of Regulation of Crh 1 0.02 0.68 0.38
77 INT342783 Prdm16 Positive_regulation of Gene_expression of Gal 1 0.02 0.72 0.37
78 INT304340 FKBP5 Regulation of NR3C1 1 0.05 0.71 0.37
79 INT112617 Pdpk1 Regulation of Il1b 1 0.03 1.11 0.36
80 INT112618 Pdpk1 Regulation of Tnf 1 0.03 1.11 0.36
81 INT202810 Pin1 Regulation of Csf2 1 0.03 0.82 0.36
82 INT222721 Binding of HTR1A and Pdpk1 1 0.00 0.35 0.33
83 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
84 INT235884 Htr3a Regulation of Nr3c1 1 0.00 0.63 0.32
85 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
86 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
87 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
88 INT55404 Binding of ENG and Th 1 0.02 0 0.3
89 INT166165 Binding of TGFB3 and Bmp2 1 0.00 0 0.3
90 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
91 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
92 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
93 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
94 INT29137 ENG Regulation of POMC 1 0.00 0 0.28
95 INT29139 ENG Regulation of Oprl1 1 0.00 0 0.28
96 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
97 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
98 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
99 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
100 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
101 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
102 INT32156 Binding of ENG and Oprd1 1 0.00 0 0.26
103 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
104 INT18994 Negative_regulation of Pdpk1 Negative_regulation of Regulation of Cck 1 0.10 0 0.26
105 INT32149 Binding of ENG and LLGL1 1 0.11 0 0.26
106 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
107 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26
108 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
109 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
110 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
111 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
112 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
113 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
114 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
115 INT210803 Igh-Dex Regulation of Nr3c1 1 0.05 0 0.24
116 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
117 INT333927 GLUL Positive_regulation of HSPA5 1 0.17 0.78 0.24
118 INT43713 ENG Regulation of Prl 1 0.00 0 0.23
119 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
120 INT192864 Binding of Hspa5 and Mela 1 0.25 1.06 0.22
121 INT202808 Binding of Pin1 and Hnrpd 1 0.08 0.84 0.22
122 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
123 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
124 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
125 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
126 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2
127 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
128 INT14869 Binding of EGF and TGFB3 1 0.14 0.69 0.19
129 INT79651 PTGS2 Positive_regulation of Phosphorylation of NR3C1 1 0.07 0.1 0.19
130 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
131 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
132 INT58006 DYT10 Positive_regulation of Positive_regulation of Pdpk1 1 0.02 0.14 0.18
133 INT52306 Nr3c1 Negative_regulation of Transcription of Penk 1 0.26 0 0.18
134 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18
135 INT221231 Pdpk1 Positive_regulation of Akt1 1 0.09 0.13 0.18
136 INT221244 Pdpk1 Positive_regulation of Phosphorylation of Akt1 1 0.09 0.13 0.18
137 INT130690 Gene_expression of HSPA5 Negative_regulation of Positive_regulation of DDIT3 1 0.21 0.58 0.17
138 INT179849 Il11 Regulation of Positive_regulation of Pdpk1 1 0.05 0.07 0.17
139 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
140 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
141 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
142 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
143 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
144 INT146744 Binding of NR3C1 and PLA2G4A 1 0.26 0.25 0.15
145 INT349559 Mtor Regulation of Pdpk1 1 0.03 0.42 0.14
146 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
147 INT1233 Gcg Positive_regulation of Pdpk1 1 0.27 0 0.14
148 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14
149 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
150 INT202813 Pin1 Positive_regulation of Regulation of TH1L 1 0.50 0 0.14
151 INT276813 NR3C1 Regulation of Gene_expression of Hgs 1 0.03 1.09 0.13
152 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
153 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
154 INT32294 ENG Positive_regulation of Trh 1 0.01 0 0.13
155 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
156 INT141881 Binding of MECOM and Tnfrsf1a 1 0.00 1.17 0.13
157 INT276767 NR3C1 Regulation of Gene_expression of UTS2R 1 0.00 1.09 0.13
158 INT244847 Lbx1 Positive_regulation of Skor1 1 0.47 0.08 0.13
159 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
160 INT68493 Pomc Positive_regulation of NR3C1 1 0.02 0 0.12
161 INT166802 PEG10 Regulation of Gene_expression of LAMC2 1 0.08 0 0.12
162 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
163 INT128551 Binding of Cebpb and Nr3c1 1 0.06 0.15 0.11
164 INT352030 Binding of NR3C1 and IL2 1 0.15 0.5 0.11
165 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
166 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
167 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
168 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
169 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
170 INT60399 ENG Regulation of Localization of Prl 1 0.04 0.57 0.1
171 INT158011 KLRF1 Positive_regulation of ENG 1 0.03 0.39 0.09
172 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
173 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
174 INT125089 Binding of HLA-B and TDGF1 1 0.24 0.18 0.09
175 INT158012 Binding of ENG and FLT1 1 0.21 0.39 0.09
176 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09
177 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
178 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
179 INT32290 ENG Regulation of Positive_regulation of Trh 1 0.01 0 0.09
180 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
181 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
182 INT245642 Nr3c1 Regulation of Gene_expression of Hpse 1 0.05 1.33 0.08
183 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
184 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
185 INT227565 NR3C1 Positive_regulation of UFM1 1 0.00 0.07 0.08
186 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08
187 INT215880 Car2 Regulation of Hspa5 1 0.09 0.66 0.08
188 INT202807 Pin1 Regulation of Binding of Hnrpd 1 0.06 0.14 0.08
189 INT210787 Ihh Negative_regulation of Nr3c1 1 0.33 0 0.08
190 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
191 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
192 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
193 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
194 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
195 INT278613 NR3C1 Regulation of Gene_expression of SULT2A1 1 0.02 0.05 0.07
196 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
197 INT25491 TFPI Regulation of Localization of ENG 1 0.27 0.31 0.06
198 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
199 INT25490 Binding of ENG and TFPI 1 0.27 0.4 0.06
200 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of transforming growth factor beta receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of transforming growth factor beta receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1232 Positive_regulation of Pdpk1 78 0.42 24.33 50.17
2 INT18992 Negative_regulation of Pdpk1 53 0.42 19.02 40.95
3 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
4 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
5 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
6 INT10799 Localization of ENG 63 0.78 18.67 27.28
7 INT48769 Regulation of Pdpk1 20 0.35 9.78 20.36
8 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
9 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
10 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
11 INT7674 Regulation of ENG 42 0.30 11.41 14.44
12 INT26733 Gene_expression of Pdpk1 17 0.48 5.74 13.91
13 INT5630 Localization of Pdpk1 10 0.45 5.21 11.36
14 INT79656 Positive_regulation of NR3C1 14 0.68 6.38 10.83
15 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7
16 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
17 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65
18 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
19 INT104013 Negative_regulation of Gene_expression of Pdpk1 4 0.31 2.36 7.89
20 INT66318 Gene_expression of NR3C1 26 0.76 20 7.55
21 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
22 INT49749 Negative_regulation of Nr3c1 13 0.43 6.25 7.36
23 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
24 INT71824 Phosphorylation of Pdpk1 14 0.38 4.9 6.86
25 INT23375 Binding of ENG 17 0.47 6.02 6.46
26 INT7564 Positive_regulation of Nr3c1 16 0.68 4.98 6.25
27 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
28 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
29 INT38686 Binding of NR3C1 20 0.48 9.25 5.99
30 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
31 INT52819 Negative_regulation of NR3C1 14 0.50 7.22 5.84
32 INT55077 Positive_regulation of Positive_regulation of Pdpk1 6 0.26 1.77 5.78
33 INT68465 Positive_regulation of Gene_expression of Pdpk1 7 0.19 2.35 5.49
34 INT52814 Negative_regulation of Nr3c1 9 0.57 5.69 5.41
35 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38
36 INT60585 Regulation of TP53 59 0.59 54.55 5.21
37 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
38 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
39 INT52818 Localization of NR3C1 13 0.69 7.65 4.57
40 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
41 INT125282 Negative_regulation of Positive_regulation of NR3C1 3 0.57 0.54 4.31
42 INT1231 Negative_regulation of Positive_regulation of Pdpk1 6 0.35 1.88 4.13
43 INT49712 Regulation of Nr3c1 10 0.28 5.65 4.06
44 INT57157 Gene_expression of TDGF1 5 0.75 3.97 4.02
45 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
46 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
47 INT64919 Gene_expression of Prdm16 6 0.75 11.63 3.5
48 INT15844 Positive_regulation of Localization of ENG 7 0.67 4.2 3.47
49 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44
50 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31
51 INT8103 Binding of TP53 46 0.44 40.2 2.96
52 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
53 INT32222 Negative_regulation of Gene_expression of ENG 9 0.37 2.23 2.89
54 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
55 INT47846 Negative_regulation of Localization of Pdpk1 2 0.33 1.12 2.75
56 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
57 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
58 INT96763 Positive_regulation of Localization of Pdpk1 1 0.39 2.08 2.65
59 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64
60 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62
61 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
62 INT202792 Negative_regulation of Pin1 1 0.56 3.77 2.37
63 INT55952 Transcription of TP53 16 0.61 12.14 2.36
64 INT8484 Localization of Nr3c1 8 0.53 3.12 2.32
65 INT13997 Regulation of Gene_expression of ENG 11 0.36 3.31 2.31
66 INT12133 Regulation of Localization of ENG 3 0.03 0.57 2.24
67 INT125281 Positive_regulation of Positive_regulation of NR3C1 1 0.49 0 2.11
68 INT141833 Gene_expression of WNT1 14 0.75 10.57 2.1
69 INT51316 Regulation of NR3C1 7 0.51 4.23 2.09
70 INT13075 Binding of NKX2-1 6 0.05 0.12 2.08
71 INT99039 Negative_regulation of Gene_expression of Nr3c1 2 0.37 1.96 2.08
72 INT29035 Negative_regulation of Wnt1 3 0.41 1.47 2
73 INT158442 Gene_expression of Nkx2-1 21 0.59 8.47 1.99
74 INT32135 Positive_regulation of Positive_regulation of ENG 2 0.02 0.98 1.99
75 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
76 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
77 INT135313 Regulation of Gene_expression of Nr3c1 3 0.39 3.44 1.94
78 INT52305 Binding of Nr3c1 7 0.15 3.95 1.9
79 INT65855 Localization of TP53 18 0.76 17.08 1.89
80 INT167456 Regulation of Gene_expression of Nr3c1 2 0.14 0.76 1.87
81 INT26735 Regulation of Gene_expression of Pdpk1 2 0.24 0.56 1.84
82 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
83 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
84 INT26750 Positive_regulation of Nr3c1 6 0.46 5.46 1.75
85 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
86 INT104014 Negative_regulation of Phosphorylation of Pdpk1 2 0.23 0.59 1.72
87 INT15845 Negative_regulation of Localization of ENG 3 0.05 0.76 1.71
88 INT49448 Positive_regulation of Positive_regulation of Nr3c1 1 0.38 0 1.55
89 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
90 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
91 INT7578 Transcription of Nr3c1 5 0.32 0.43 1.47
92 INT118559 Positive_regulation of Hspa5 20 0.61 15.66 1.45
93 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
94 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
95 INT172953 Binding of Trp53 33 0.37 20.76 1.41
96 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
97 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
98 INT67464 Positive_regulation of Negative_regulation of Pdpk1 1 0.19 0.15 1.41
99 INT118927 Positive_regulation of Phosphorylation of Pdpk1 2 0.04 0.76 1.38
100 INT145221 Binding of Tp53 10 0.37 8.59 1.37
101 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
102 INT32717 Negative_regulation of Regulation of ENG 3 0.00 0.43 1.25
103 INT221206 Phosphorylation of Pdpk1 3 0.53 0.13 1.25
104 INT333924 Positive_regulation of TDGF1 1 0.02 1.03 1.24
105 INT141834 Negative_regulation of Gene_expression of WNT1 3 0.57 1.31 1.2
106 INT104011 Transcription of Pdpk1 1 0.28 0 1.2
107 INT104012 Regulation of Transcription of Pdpk1 1 0.14 0 1.2
108 INT26734 Binding of Pdpk1 4 0.29 1.01 1.19
109 INT174156 Localization of Trp53 16 0.72 13.52 1.18
110 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
111 INT333920 Negative_regulation of Gene_expression of TDGF1 1 0.02 0.89 1.16
112 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
113 INT51863 Negative_regulation of Negative_regulation of ENG 2 0.04 0.51 1.13
114 INT78266 Localization of NKX2-1 2 0.73 0.16 1.12
115 INT91776 Negative_regulation of Gene_expression of Nr3c1 4 0.42 2.26 1.03
116 INT15040 Gene_expression of NKX2-1 8 0.65 3.95 1.02
117 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
118 INT166449 Positive_regulation of Gene_expression of NR3C1 4 0.68 3.73 0.99
119 INT68467 Regulation of Regulation of Pdpk1 1 0.05 0.09 0.96
120 INT333922 Negative_regulation of TDGF1 1 0.02 0.91 0.96
121 INT159015 Positive_regulation of Localization of HSPA5 1 0.36 0.33 0.88
122 INT202790 Binding of Pin1 1 0.46 3.02 0.88
123 INT13074 Positive_regulation of NKX2-1 4 0.19 0.86 0.87
124 INT159013 Localization of HSPA5 2 0.42 0.32 0.87
125 INT248304 Positive_regulation of Localization of Nr3c1 2 0.10 1.39 0.87
126 INT99156 Binding of HSPA5 3 0.38 0.57 0.84
127 INT141835 Negative_regulation of WNT1 2 0.41 1.02 0.83
128 INT202786 Regulation of Pin1 1 0.43 2.16 0.83
129 INT202628 Gene_expression of Wnt1 20 0.67 9.2 0.82
130 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
131 INT14871 Binding of TGFB3 3 0.13 1.2 0.78
132 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
133 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
134 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
135 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
136 INT15039 Negative_regulation of NKX2-1 3 0.21 0 0.72
137 INT68486 Transcription of NR3C1 4 0.20 0.19 0.69
138 INT202806 Gene_expression of Pin1 1 0.74 1.87 0.66
139 INT11763 Positive_regulation of Regulation of ENG 1 0.01 0.97 0.64
140 INT7576 Positive_regulation of Transcription of Nr3c1 1 0.19 0.3 0.62
141 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
142 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
143 INT96323 Regulation of Transcription of Nr3c1 1 0.20 0 0.59
144 INT170768 Regulation of Gene_expression of NR3C1 3 0.42 2.61 0.58
145 INT83353 Negative_regulation of Binding of NR3C1 3 0.24 1.09 0.57
146 INT79249 Regulation of Negative_regulation of Pdpk1 1 0.03 0.09 0.57
147 INT228167 Negative_regulation of Peg10 18 0.02 7.64 0.54
148 INT202801 Positive_regulation of Pin1 1 0.67 1.37 0.52
149 INT98037 Negative_regulation of Negative_regulation of Pdpk1 1 0.05 0.26 0.52
150 INT231163 Binding of Peg10 7 0.06 3.41 0.5
151 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
152 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
153 INT129748 Transcription of Nr3c1 1 0.58 0.53 0.48
154 INT244797 Gene_expression of Skor1 1 0.65 0.26 0.48
155 INT129747 Regulation of Transcription of Nr3c1 1 0.22 0.53 0.48
156 INT267837 Gene_expression of TGFB1I1 1 0.15 1.38 0.48
157 INT290850 Regulation of Positive_regulation of Nr3c1 1 0.12 0.75 0.47
158 INT103896 Negative_regulation of Gene_expression of NR3C1 1 0.09 0.83 0.45
159 INT154748 Positive_regulation of Gene_expression of Hspa5 11 0.44 7.66 0.44
160 INT231144 Gene_expression of Peg10 5 0.27 1.91 0.44
161 INT228057 Positive_regulation of WNT1 1 0.49 1.8 0.44
162 INT52815 Regulation of Negative_regulation of Nr3c1 1 0.08 0.05 0.43
163 INT202805 Negative_regulation of Negative_regulation of Pin1 1 0.41 0.77 0.43
164 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
165 INT130698 Negative_regulation of Positive_regulation of HSPA5 2 0.36 1.58 0.42
166 INT175024 Positive_regulation of Localization of NR3C1 1 0.10 0.5 0.41
167 INT314126 Positive_regulation of Gene_expression of Prdm16 4 0.67 4.57 0.4
168 INT102722 Phosphorylation of PDPK1 3 0.82 1.39 0.4
169 INT27659 Localization of TGFB3 3 0.29 0.52 0.4
170 INT38685 Regulation of Binding of NR3C1 2 0.61 0.59 0.4
171 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
172 INT256247 Positive_regulation of Peg10 4 0.02 4.37 0.39
173 INT236107 Binding of Pdpk1 2 0.26 1.38 0.39
174 INT236105 Negative_regulation of Binding of Pdpk1 1 0.30 1.22 0.39
175 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36
176 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
177 INT128546 Binding of Nr3c1 4 0.34 1.4 0.35
178 INT179816 Positive_regulation of Pdpk1 4 0.31 0.36 0.35
179 INT216379 Positive_regulation of Gene_expression of WNT1 5 0.30 3.1 0.34
180 INT342781 Negative_regulation of Gene_expression of Prdm16 1 0.02 0.97 0.34
181 INT238439 Positive_regulation of PDPK1 2 0.20 1.3 0.31
182 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
183 INT204368 Gene_expression of SIRT1 17 0.76 4.48 0.3
184 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
185 INT17138 Positive_regulation of Skil 2 0.35 0.59 0.3
186 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
187 INT184716 Binding of Smad7 2 0.34 0.91 0.29
188 INT14873 Positive_regulation of Gene_expression of TGFB3 2 0.25 1.14 0.29
189 INT163891 Positive_regulation of Phosphorylation of MECOM 1 0.00 0.4 0.29
190 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
191 INT163894 Phosphorylation of MECOM 1 0.00 0.4 0.28
192 INT202791 Phosphorylation of Pin1 1 0.78 0.61 0.28
193 INT333957 Regulation of HSPA5 3 0.52 0.61 0.27
194 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
195 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
196 INT102717 Gene_expression of PDPK1 1 0.77 3.11 0.25
197 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
198 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
199 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
200 INT147840 Gene_expression of Tgfb3 1 0.03 0 0.22
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