GO:0030513

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Name positive regulation of BMP signaling pathway
Categary Process
Go Slim No
Go Link GO:0030513
Unique Molecular Interactions 182
Total Molecular Interactions 228
Total Single Events 1500
Pain Genes Associated 24

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of BMP signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of BMP signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT134215 CRH Positive_regulation of ENG 1 0.13 1.22 2.06
2 INT31445 ENG Positive_regulation of Localization of Prl 4 0.01 0 1.77
3 INT167321 Binding of ENG and OPRM1 1 0.27 0.63 1.76
4 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69
5 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68
6 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68
7 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
8 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
9 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
10 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
11 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
12 INT31444 ENG Positive_regulation of Prl 1 0.01 0 1.14
13 INT134213 CRH Positive_regulation of Gene_expression of ENG 1 0.13 0.61 1.03
14 INT32187 Binding of ENG and Negative_regulation of Localization of LH 1 0.01 0 0.91
15 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91
16 INT101259 Gata6 Negative_regulation of Gene_expression of ALOX15 1 0.42 0.67 0.89
17 INT101258 Gene_expression of Gata6 Negative_regulation of Positive_regulation of ALOX15 1 0.42 0.65 0.87
18 INT148452 Inhbe Regulation of Acvrl1 1 0.01 0.69 0.69
19 INT32719 ENG Regulation of LH 2 0.00 0 0.64
20 INT31443 ENG Positive_regulation of Localization of Pomc 1 0.00 0 0.63
21 INT109065 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.00 0 0.58
22 INT134214 CRH Regulation of Localization of ENG 1 0.14 0.39 0.53
23 INT32151 ENG Positive_regulation of Gene_expression of IFNA1 1 0.37 0 0.53
24 INT32291 ENG Negative_regulation of LH 2 0.00 0 0.52
25 INT171897 Binding of Bmpr2 and Il1 1 0.03 0.84 0.52
26 INT30618 Slc3a1 Regulation of ENG 1 0.00 0 0.5
27 INT30619 Pomc Regulation of ENG 1 0.00 0 0.5
28 INT102214 ENG Negative_regulation of HP 1 0.01 0 0.49
29 INT60872 Binding of ENG and Abat 1 0.00 0 0.49
30 INT60871 ENG Regulation of Localization of LH 1 0.00 0 0.49
31 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
32 INT43695 ENG Regulation of Regulation of Prl 1 0.00 0 0.47
33 INT60870 ENG Negative_regulation of Localization of LH 1 0.00 0 0.47
34 INT102213 Binding of ENG and HP 1 0.01 0 0.47
35 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
36 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
37 INT202516 Positive_regulation of Binding of ENG and Penk 1 0.03 0.58 0.42
38 INT202515 Binding of ENG and Penk 1 0.02 0.57 0.41
39 INT81991 Bmpr2 Positive_regulation of Gene_expression of ODF1 1 0.03 1.59 0.41
40 INT32720 Negative_regulation of ENG Regulation of LH 1 0.00 0 0.41
41 INT168202 Msx1 Negative_regulation of Gene_expression of Mc1r 1 0.21 0.49 0.35
42 INT194860 BMPR2 Positive_regulation of IL1B 1 0.01 0.61 0.34
43 INT55404 Binding of ENG and Th 1 0.02 0 0.3
44 INT75056 Binding of MC1R and Msx1 1 0.00 0.17 0.29
45 INT29137 ENG Regulation of POMC 1 0.00 0 0.28
46 INT29139 ENG Regulation of Oprl1 1 0.00 0 0.28
47 INT32156 Binding of ENG and Oprd1 1 0.00 0 0.26
48 INT32149 Binding of ENG and LLGL1 1 0.11 0 0.26
49 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
50 INT311900 Acvrl1 Negative_regulation of Insrr 1 0.00 0.86 0.25
51 INT168203 Binding of Mc1r and Msx1 1 0.19 0.64 0.25
52 INT43713 ENG Regulation of Prl 1 0.00 0 0.23
53 INT311908 Acvrl1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
54 INT75057 Binding of POMC and Msx1 2 0.39 0.6 0.2
55 INT297545 Pou3f3 Regulation of Hes1 1 0.05 0.41 0.2
56 INT287894 VEGFA Positive_regulation of Localization of BMP4 1 0.04 2.49 0.2
57 INT251347 Binding of Bmpr2 and Limk1 1 0.18 1.51 0.16
58 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
59 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
60 INT97547 KITLG Negative_regulation of Msx1 1 0.00 0.08 0.15
61 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
62 INT97542 Pomc Negative_regulation of Msx1 1 0.13 0.07 0.15
63 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
64 INT97545 Gtf3a Negative_regulation of Msx1 1 0.02 0.08 0.15
65 INT32294 ENG Positive_regulation of Trh 1 0.01 0 0.13
66 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12
67 INT214152 Binding of Mc4r and Msx1 1 0.03 0.24 0.11
68 INT297548 Neurod1 Regulation of Hes1 1 0.05 0.2 0.1
69 INT287887 WNT1 Positive_regulation of Localization of BMP4 1 0.04 1.13 0.1
70 INT60399 ENG Regulation of Localization of Prl 1 0.04 0.57 0.1
71 INT158011 KLRF1 Positive_regulation of ENG 1 0.03 0.39 0.09
72 INT158012 Binding of ENG and FLT1 1 0.21 0.39 0.09
73 INT214168 Msx1 Positive_regulation of Gene_expression of DST 1 0.00 0.13 0.09
74 INT32290 ENG Regulation of Positive_regulation of Trh 1 0.01 0 0.09
75 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
76 INT288374 Binding of MLANA and Msx1 1 0.09 0 0.08
77 INT189550 Binding of BMPR2 and PAH 1 0.06 2.68 0.08
78 INT262214 Binding of Msx2 and Nr1i2 1 0.19 0.55 0.06
79 INT311903 Acvrl1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
80 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
81 INT25491 TFPI Regulation of Localization of ENG 1 0.27 0.31 0.06
82 INT311910 Acvrl1 Positive_regulation of Phosphorylation of Smad1 1 0.12 0.24 0.06
83 INT25490 Binding of ENG and TFPI 1 0.27 0.4 0.06
84 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
85 INT339110 ERBB2 Positive_regulation of GATA6 1 0.31 0.67 0.06
86 INT214146 Msx1 Positive_regulation of Gene_expression of Nucb2 1 0.05 0.19 0.05
87 INT181814 Gsk3b Regulation of Gata4 1 0.06 0.37 0.05
88 INT210261 Bmp4 Regulation of Gene_expression of Tff3 1 0.64 0 0.05
89 INT32293 ENG Regulation of Positive_regulation of Gnrh1 1 0.00 0 0.04
90 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
91 INT32297 ENG Regulation of Positive_regulation of LH 1 0.00 0 0.04
92 INT320786 Binding of Eng and Kdr 1 0.04 1.17 0.04
93 INT306560 BMP4 Positive_regulation of MAPK1 1 0.09 0.09 0.03
94 INT336752 Sparc Regulation of Regulation of Ilk 1 0.30 0.71 0.03
95 INT319218 Bmpr2 Negative_regulation of Smad2 1 0.17 0.12 0.03
96 INT319219 Bmpr2 Positive_regulation of Smad1 1 0.18 0.29 0.03
97 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
98 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
99 INT319217 Bmpr2 Positive_regulation of Gene_expression of Smad1 1 0.19 0.11 0.03
100 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
101 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
102 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
103 INT340614 Binding of ENG and MMP9 1 0.16 0.14 0
104 INT205409 Binding of BMP6 and BMPR2 1 0.07 0.05 0
105 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
106 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
107 INT275231 Binding of ACVRL1 and AK3 1 0.01 0.72 0
108 INT314373 Binding of Cd34 and Eng 1 0.08 0.9 0
109 INT269944 Gata6 Regulation of Gene_expression of Foxj1 1 0.19 0 0
110 INT310186 Binding of Gdf2 and Bmpr2 1 0.02 0 0
111 INT264735 Binding of Hes1 and Mir199b 1 0.08 0.93 0
112 INT183090 Gene_expression of SULF1 Positive_regulation of Phosphorylation of FGF2 1 0.19 0.42 0
113 INT32148 POMC Regulation of ENG 1 0.24 0 0
114 INT262172 Nr1i2 Regulation of Msx2 1 0.12 0.53 0
115 INT264738 Mir199b Regulation of Gene_expression of Hes1 1 0.08 0.89 0
116 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
117 INT356083 Binding of App and Notch1 1 0.02 0.2 0
118 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
119 INT15847 Avp Positive_regulation of Localization of ENG 1 0.07 0 0
120 INT264736 Hes1 Regulation of Notch2 1 0.20 0.13 0
121 INT340613 Binding of COL4A4 and ENG 1 0.07 0.14 0
122 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
123 INT183093 SULF1 Negative_regulation of Binding of FGF2 1 0.17 0.41 0
124 INT225873 Ilk Positive_regulation of AKT1 1 0.00 0.07 0
125 INT329746 ENG Positive_regulation of SMAD1 1 0.15 0.44 0
126 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
127 INT196023 Bmp2 Negative_regulation of Gene_expression of Bmp4 1 0.09 0.07 0
128 INT225876 PIK3CG Positive_regulation of Ilk 1 0.00 0 0
129 INT205410 Binding of BMP2 and BMPR2 1 0.07 0.05 0
130 INT217780 MIR181A1 Regulation of GATA6 1 0.17 0.7 0
131 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
132 INT228288 Binding of ENG and Ptprc 1 0.06 0.25 0
133 INT340919 Binding of Fkbp8 and Ptplad1 1 0.14 0.17 0
134 INT274434 Binding of Gata4 and Zfpm2 1 0.12 0.56 0
135 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
136 INT196021 Bmp2 Positive_regulation of Gene_expression of Bmp4 1 0.09 0.08 0
137 INT197304 Ahr Regulation of Hes1 1 0.06 0.17 0
138 INT264731 Gene_expression of Hes1 Negative_regulation of Positive_regulation of Musd1 1 0.00 0.18 0
139 INT197315 Hes5 Regulation of Atoh1 1 0.00 0.14 0
140 INT310187 Acvrl1 Regulation of Gene_expression of Bmpr2 1 0.04 0 0
141 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
142 INT228287 Binding of ENG and Cd14 1 0.20 0.25 0
143 INT160761 Cma1 Regulation of Positive_regulation of ENG 1 0.01 0.07 0
144 INT196022 Bmp7 Regulation of Bmp4 1 0.06 0.06 0
145 INT310189 Binding of Acvrl1 and Gdf2 1 0.01 0 0
146 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
147 INT197314 Hes5 Regulation of Ascl1 1 0.00 0.14 0
148 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
149 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
150 INT264729 Mir199b Regulation of Hes1 1 0.05 0.25 0
151 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0
152 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
153 INT197310 Hes1 Regulation of Ascl1 1 0.01 0.14 0
154 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
155 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
156 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
157 INT264734 Mir199b Negative_regulation of Negative_regulation of Hes1 1 0.07 0.1 0
158 INT314372 Binding of Eng and Ptprc 1 0.04 0.84 0
159 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0
160 INT264739 Mir199b Negative_regulation of Gene_expression of Hes1 1 0.07 0.82 0
161 INT264737 Hes1 Regulation of Shh 1 0.19 0.13 0
162 INT347297 ILK Regulation of Gene_expression of AKT1 1 0.21 0.62 0
163 INT183134 Binding of SULF1 and Panc1 1 0.03 0.42 0
164 INT283711 Sox11 Regulation of 4930579C15Rik 1 0.28 0.74 0
165 INT264733 Hes1 Regulation of Mir199b 1 0.05 0.43 0
166 INT269956 Gata6 Regulation of Gene_expression of Scgb1a1 1 0.17 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of BMP signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of BMP signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT7675 Gene_expression of ENG 146 0.77 45.35 34.6
2 INT11764 Positive_regulation of ENG 78 0.61 27.65 33.69
3 INT10799 Localization of ENG 63 0.78 18.67 27.28
4 INT7674 Regulation of ENG 42 0.30 11.41 14.44
5 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61
6 INT23375 Binding of ENG 17 0.47 6.02 6.46
7 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
8 INT183119 Gene_expression of SULF1 1 0.75 46.71 5.44
9 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
10 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
11 INT15844 Positive_regulation of Localization of ENG 7 0.67 4.2 3.47
12 INT32222 Negative_regulation of Gene_expression of ENG 9 0.37 2.23 2.89
13 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
14 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68
15 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
16 INT22071 Positive_regulation of Gene_expression of ENG 13 0.50 5.44 2.62
17 INT32920 Gene_expression of Msx1 19 0.71 4.24 2.42
18 INT13997 Regulation of Gene_expression of ENG 11 0.36 3.31 2.31
19 INT12133 Regulation of Localization of ENG 3 0.03 0.57 2.24
20 INT32135 Positive_regulation of Positive_regulation of ENG 2 0.02 0.98 1.99
21 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
22 INT101252 Negative_regulation of Gene_expression of Gata6 1 0.51 1.3 1.74
23 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
24 INT15845 Negative_regulation of Localization of ENG 3 0.05 0.76 1.71
25 INT101244 Regulation of Gata6 3 0.40 1.52 1.7
26 INT81982 Gene_expression of Bmpr2 36 0.60 14.58 1.55
27 INT89871 Gene_expression of Gata4 11 0.69 1.05 1.53
28 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
29 INT310167 Gene_expression of Acvrl1 2 0.40 5.47 1.4
30 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
31 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
32 INT32717 Negative_regulation of Regulation of ENG 3 0.00 0.43 1.25
33 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24
34 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
35 INT138726 Positive_regulation of Gene_expression of Msx1 5 0.53 1.73 1.2
36 INT110780 Localization of Notch1 2 0.06 0.47 1.19
37 INT98595 Regulation of ILK 6 0.62 3.84 1.16
38 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
39 INT51863 Negative_regulation of Negative_regulation of ENG 2 0.04 0.51 1.13
40 INT183127 Localization of SULF1 1 0.77 3.45 1.13
41 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
42 INT61643 Gene_expression of ACVRL1 9 0.51 9.04 1.03
43 INT109069 Transcription of Gata4 4 0.64 0.52 1.01
44 INT109070 Positive_regulation of Transcription of Gata4 1 0.03 0 1.01
45 INT61642 Binding of ACVRL1 5 0.31 7.03 0.87
46 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
47 INT101248 Negative_regulation of Gata6 1 0.37 0.83 0.85
48 INT101251 Negative_regulation of Positive_regulation of Gata6 1 0.38 0.83 0.85
49 INT101250 Positive_regulation of Gata6 1 0.41 0.83 0.84
50 INT101245 Transcription of Gata6 2 0.47 0.85 0.82
51 INT311884 Negative_regulation of Acvrl1 1 0.30 2.16 0.81
52 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
53 INT265328 Positive_regulation of Acvrl1 5 0.40 3.18 0.78
54 INT95617 Regulation of Msx1 2 0.56 1.05 0.73
55 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
56 INT75043 Binding of Msx1 6 0.35 2.36 0.65
57 INT11763 Positive_regulation of Regulation of ENG 1 0.01 0.97 0.64
58 INT264709 Gene_expression of Hes1 24 0.76 7.04 0.63
59 INT96422 Gene_expression of Bmp4 18 0.69 3.26 0.63
60 INT89867 Negative_regulation of Gene_expression of Gata4 3 0.38 0.17 0.61
61 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
62 INT183133 Negative_regulation of Localization of SULF1 1 0.41 1.34 0.59
63 INT90939 Positive_regulation of Eng 9 0.64 4.62 0.57
64 INT32921 Positive_regulation of Msx1 4 0.47 0.99 0.57
65 INT89868 Negative_regulation of Gata4 1 0.38 0 0.57
66 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
67 INT98590 Negative_regulation of Positive_regulation of ILK 1 0.43 1.17 0.55
68 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
69 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
70 INT110924 Regulation of BMPR2 3 0.17 1.75 0.54
71 INT98592 Gene_expression of ILK 6 0.78 5.23 0.53
72 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
73 INT98594 Positive_regulation of ILK 3 0.70 1.74 0.49
74 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
75 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
76 INT247307 Negative_regulation of Msx1 3 0.22 0.11 0.42
77 INT180688 Transcription of Bmp4 3 0.58 0.35 0.41
78 INT180702 Positive_regulation of Transcription of Bmp4 3 0.42 0.35 0.41
79 INT183114 Positive_regulation of Gene_expression of SULF1 1 0.48 7.61 0.37
80 INT311889 Negative_regulation of Gene_expression of Acvrl1 1 0.22 1.27 0.37
81 INT150330 Gene_expression of BMPR2 7 0.29 4.22 0.34
82 INT251324 Binding of Bmpr2 5 0.23 2.99 0.34
83 INT201967 Positive_regulation of Bmpr2 4 0.31 1.24 0.34
84 INT183116 Positive_regulation of SULF1 1 0.67 3.22 0.34
85 INT109058 Positive_regulation of Gene_expression of Gata4 2 0.29 0 0.33
86 INT283698 Gene_expression of Sox11 1 0.68 4.6 0.33
87 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
88 INT311895 Regulation of Positive_regulation of Acvrl1 1 0.23 0.97 0.29
89 INT159213 Gene_expression of BMP4 8 0.74 2.1 0.28
90 INT159212 Positive_regulation of Gene_expression of BMP4 2 0.66 0.91 0.28
91 INT139741 Positive_regulation of Gene_expression of ACVRL1 2 0.38 1.33 0.28
92 INT98593 Positive_regulation of Positive_regulation of ILK 1 0.50 0.58 0.28
93 INT251327 Regulation of Binding of Bmpr2 1 0.20 2.27 0.27
94 INT214128 Negative_regulation of Gene_expression of Msx1 3 0.53 1.25 0.26
95 INT185009 Negative_regulation of BMP4 2 0.56 1.04 0.25
96 INT98597 Positive_regulation of Gene_expression of ILK 4 0.70 3.08 0.23
97 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
98 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
99 INT81981 Negative_regulation of Bmpr2 4 0.27 2.88 0.21
100 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
101 INT150332 Negative_regulation of Gene_expression of BMPR2 1 0.01 0 0.2
102 INT193945 Binding of Notch1 7 0.15 1.28 0.19
103 INT150331 Positive_regulation of Gene_expression of BMPR2 2 0.02 0.59 0.19
104 INT123935 Positive_regulation of BMPR2 3 0.26 1.65 0.18
105 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
106 INT264701 Negative_regulation of Gene_expression of Hes1 1 0.42 0.73 0.18
107 INT131558 Protein_catabolism of ENG 1 0.01 0 0.18
108 INT98591 Positive_regulation of Regulation of ILK 1 0.47 0.7 0.18
109 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
110 INT189590 Positive_regulation of ACVRL1 3 0.08 1.3 0.16
111 INT189604 Negative_regulation of BMPR2 2 0.26 0.95 0.15
112 INT192082 Localization of BMPR2 1 0.32 0.55 0.15
113 INT297455 Positive_regulation of Gdf2 1 0.01 0.75 0.15
114 INT90940 Binding of Eng 5 0.35 1.92 0.13
115 INT183125 Negative_regulation of SULF1 2 0.42 2.26 0.13
116 INT166623 Binding of BMPR2 1 0.29 0.35 0.13
117 INT214127 Localization of Msx1 1 0.06 0.21 0.13
118 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
119 INT210224 Localization of Acvrl1 1 0.03 0.33 0.12
120 INT287912 Localization of BMP4 1 0.18 1.13 0.1
121 INT183124 Regulation of Gene_expression of SULF1 1 0.59 1.92 0.1
122 INT201962 Transcription of Bmpr2 6 0.37 3.51 0.09
123 INT196033 Negative_regulation of Gene_expression of Bmp4 3 0.21 0.45 0.09
124 INT26064 Regulation of Positive_regulation of ENG 1 0.01 0.1 0.09
125 INT90941 Negative_regulation of Eng 1 0.31 0.25 0.09
126 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
127 INT283695 Binding of Sox11 1 0.32 0.18 0.08
128 INT254332 Negative_regulation of Gene_expression of Bmpr2 3 0.22 2.41 0.07
129 INT210243 Negative_regulation of Bmp4 1 0.55 0.55 0.07
130 INT183129 Negative_regulation of Gene_expression of SULF1 1 0.56 5.19 0.07
131 INT298251 Gene_expression of Hes5 2 0.45 0.39 0.06
132 INT339183 Positive_regulation of GATA6 1 0.16 0.66 0.06
133 INT183122 Regulation of SULF1 1 0.59 1.53 0.06
134 INT265338 Regulation of Eng 2 0.42 0.94 0.05
135 INT283696 Localization of Sox11 1 0.65 0.37 0.05
136 INT196030 Positive_regulation of Bmp4 6 0.62 2.55 0.04
137 INT210238 Positive_regulation of Negative_regulation of Bmp4 1 0.47 0 0.04
138 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
139 INT253182 Positive_regulation of Positive_regulation of Bmp4 1 0.45 0.58 0.04
140 INT264717 Negative_regulation of Hes1 7 0.42 0.77 0.03
141 INT264704 Regulation of Hes1 4 0.44 1.03 0.03
142 INT248540 Positive_regulation of Gata4 2 0.23 0.95 0.03
143 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
144 INT278039 Phosphorylation of BMPR2 1 0.08 0.26 0.03
145 INT336745 Regulation of Ilk 1 0.33 0.7 0.03
146 INT245858 Positive_regulation of Gene_expression of Eng 1 0.12 0 0.03
147 INT264702 Positive_regulation of Gene_expression of Hes1 1 0.68 1.39 0.03
148 INT278022 Phosphorylation of Bmpr2 1 0.21 0.27 0.03
149 INT302312 Localization of Bmpr2 4 0.46 0.47 0
150 INT196034 Positive_regulation of Gene_expression of Bmp4 4 0.45 0.63 0
151 INT206911 Gene_expression of Msx2 4 0.71 1.26 0
152 INT260779 Negative_regulation of Bmp4 4 0.23 0.94 0
153 INT289876 Localization of Eng 3 0.44 0.59 0
154 INT190471 Transcription of ENG 3 0.21 1.76 0
155 INT219929 Positive_regulation of Gene_expression of Bmpr2 3 0.15 0.9 0
156 INT265340 Binding of Acvrl1 3 0.30 0.46 0
157 INT265314 Regulation of Gene_expression of Eng 2 0.42 0.68 0
158 INT274404 Binding of Gata4 2 0.16 0.89 0
159 INT264719 Regulation of Gene_expression of Hes1 2 0.28 0.12 0
160 INT265324 Negative_regulation of Gene_expression of Eng 2 0.40 0.9 0
161 INT206909 Negative_regulation of Gene_expression of Msx2 2 0.53 0.29 0
162 INT196027 Binding of Bmp4 2 0.13 0.97 0
163 INT142119 Regulation of Bmp4 2 0.58 0.29 0
164 INT264708 Transcription of Hes1 1 0.67 0.83 0
165 INT206916 Positive_regulation of Gene_expression of Msx2 1 0.40 0.36 0
166 INT310166 Regulation of Acvrl1 1 0.07 0 0
167 INT264724 Negative_regulation of Positive_regulation of Notch1 1 0.03 0.77 0
168 INT217818 Gene_expression of GATA6 1 0.17 1.07 0
169 INT220772 Transcription of Msx2 1 0.46 0.08 0
170 INT283699 Positive_regulation of Sox11 1 0.35 0.62 0
171 INT310163 Positive_regulation of Positive_regulation of Acvrl1 1 0.08 0 0
172 INT197394 Protein_catabolism of Eng 1 0.07 0.13 0
173 INT347313 Binding of ILK 1 0.22 0.12 0
174 INT189611 Negative_regulation of Gene_expression of ACVRL1 1 0.06 0.29 0
175 INT339667 Localization of Bmp4 1 0.38 0.27 0
176 INT319209 Regulation of Positive_regulation of Bmpr2 1 0.28 0.08 0
177 INT189623 Transcription of BMPR2 1 0.32 0.71 0
178 INT355333 Regulation of Transcription of Bmpr2 1 0.03 0.15 0
179 INT347317 Localization of ILK 1 0.45 0 0
180 INT300174 Negative_regulation of Gene_expression of NOTCH1 1 0.04 0.53 0
181 INT264705 Binding of Hes1 1 0.35 0.07 0
182 INT297259 Regulation of ACVRL1 1 0.18 0.55 0
183 INT234247 Negative_regulation of Protein_catabolism of NOTCH1 1 0.05 0 0
184 INT310171 Phosphorylation of Eng 1 0.24 0.5 0
185 INT347314 Regulation of Gene_expression of ILK 1 0.27 1.15 0
186 INT298236 Localization of Hes5 1 0.51 0.39 0
187 INT130094 Regulation of Positive_regulation of NOTCH1 1 0.45 0.52 0
188 INT264706 Positive_regulation of Hes1 1 0.40 0.14 0
189 INT310181 Binding of Gdf2 1 0.04 0 0
190 INT310165 Negative_regulation of Transcription of Bmpr2 1 0.22 2.1 0
191 INT347307 Regulation of Binding of ILK 1 0.27 0.12 0
192 INT310182 Gene_expression of Gdf2 1 0.06 0.48 0
193 INT264723 Negative_regulation of Gene_expression of Notch1 1 0.03 0.83 0
194 INT181811 Localization of Gata4 1 0.54 0.3 0
195 INT273836 Positive_regulation of Regulation of Notch1 1 0.15 0.05 0
196 INT328768 Positive_regulation of Gene_expression of Gata6 1 0.19 0.61 0
197 INT183128 Transcription of SULF1 1 0.66 0.17 0
198 INT319208 Regulation of Bmpr2 1 0.28 0.08 0
199 INT351554 Negative_regulation of Gene_expression of BMP4 1 0.26 0 0
200 INT339154 Negative_regulation of GATA6 1 0.14 0.86 0
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