GO:0030514

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Name negative regulation of BMP signaling pathway
Categary Process
Go Slim No
Go Link GO:0030514
Unique Molecular Interactions 183
Total Molecular Interactions 247
Total Single Events 1741
Pain Genes Associated 28

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of BMP signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of BMP signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT254242 TNF Positive_regulation of Gene_expression of DKK1 1 0.14 1.24 0.91
2 INT197470 Binding of Sostdc1 and Hbtq 1 0.00 0.87 0.87
3 INT257895 Positive_regulation of Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
4 INT257896 Sostdc1 Positive_regulation of Positive_regulation of GRIN1 1 0.00 0.09 0.83
5 INT152925 Aanat Positive_regulation of Nanog 1 0.02 0.42 0.67
6 INT215543 Negative_regulation of Trim33 Negative_regulation of Gopc 1 0.15 0.35 0.48
7 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
8 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
9 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
10 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
11 INT237454 Binding of STAR and GREM1 1 0.00 0.44 0.4
12 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
13 INT85909 Binding of Oprm1 and GREM1 1 0.00 0 0.32
14 INT146893 TNF Negative_regulation of Dkk1 1 0.01 1.27 0.3
15 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
16 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28
17 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
18 INT26669 Nanog Regulation of Binding of Tlyr1 1 0.02 0 0.28
19 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
20 INT26185 Positive_regulation of Binding of GREM1 and Cyth2 1 0.00 0 0.22
21 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
22 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
23 INT26186 Binding of GREM1 and Cyth2 1 0.00 0 0.22
24 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
25 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
26 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
27 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
28 INT287884 WNT5A Positive_regulation of THEMIS 1 0.00 0.08 0.13
29 INT244847 Lbx1 Positive_regulation of Skor1 1 0.47 0.08 0.13
30 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
31 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
32 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
33 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
34 INT233510 Wnt5a Positive_regulation of Gene_expression of Il12a 1 0.03 0.33 0.1
35 INT352555 DKK1 Positive_regulation of Wnt2 1 0.01 0.25 0.1
36 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
37 INT165161 Ihh Positive_regulation of Sostdc1 1 0.58 0.07 0.09
38 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
39 INT165160 Regulation of Ihh Positive_regulation of Sostdc1 1 0.23 0.07 0.09
40 INT165158 Positive_regulation of Ihh Positive_regulation of Sostdc1 1 0.42 0.07 0.09
41 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09
42 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
43 INT211960 Wnt5a Positive_regulation of Car2 1 0.13 0.38 0.08
44 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
45 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
46 INT287879 Binding of WNT5A and FZD5 1 0.06 1.16 0.08
47 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
48 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
49 INT205119 Binding of HIVEP1 and GREM1 1 0.00 2.24 0.08
50 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
51 INT335890 Binding of Dkk1 and Lrp4 1 0.37 0.64 0.07
52 INT335886 Binding of Sost and Lrp4 1 0.28 0.65 0.07
53 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
54 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
55 INT321891 Dkk1 Negative_regulation of Wnt2 1 0.12 0.94 0.05
56 INT242167 Binding of Dkk1 and Kremen2 1 0.01 0.06 0.04
57 INT311909 Gene_expression of Smad6 Negative_regulation of Gene_expression of Col10a1 1 0.02 0.54 0.04
58 INT321890 Slc3a2 Regulation of Dkk1 1 0.01 0.93 0.04
59 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03
60 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
61 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
62 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
63 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
64 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
65 INT353288 Smad7 Negative_regulation of Phosphorylation of Tgif1 1 0.08 0.06 0.03
66 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
67 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
68 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
69 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
70 INT302311 PTH Negative_regulation of Gene_expression of SOST 1 0.29 0.59 0
71 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
72 INT197466 Dpcd Positive_regulation of Sostdc1 1 0.00 0 0
73 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
74 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
75 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0
76 INT288584 Cav1 Regulation of Gene_expression of Kcnma1 1 0.14 0 0
77 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
78 INT288588 Binding of Cav1 and Neu3 1 0.01 0 0
79 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
80 INT145336 Binding of PYGO1 and Positive_regulation of Transcription of DKK1 1 0.07 0 0
81 INT293982 MYC Negative_regulation of SFRP1 1 0.21 0.62 0
82 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0
83 INT145333 Binding of BCL9 and Positive_regulation of Transcription of DKK1 1 0.41 0 0
84 INT218663 Olr811 Positive_regulation of Gene_expression of Smad7 1 0.01 0.45 0
85 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0
86 INT347124 Binding of FZD1 and Lrp1 1 0.11 0.24 0
87 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0
88 INT306626 Gprasp1 Negative_regulation of Fstl3 1 0.08 0 0
89 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
90 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0
91 INT308352 Binding of Ctnnd2 and Tcf7l2 1 0.15 0.74 0
92 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0
93 INT134836 Binding of SMAD7 and YAP1 1 0.53 0.89 0
94 INT313842 Mstn Regulation of Gene_expression of Fstl3 1 0.32 0.08 0
95 INT233520 Tlr4 Positive_regulation of Fzd1 1 0.03 0.09 0
96 INT280961 Binding of Cav1 and Cpox 1 0.04 0 0
97 INT254432 Binding of Best1 and Sost 1 0.12 0.69 0
98 INT288587 Cav1 Regulation of Binding of Kcnma1 1 0.14 0 0
99 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
100 INT236528 Binding of Cav1 and Flna 1 0.06 0.09 0
101 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
102 INT288590 Binding of Cav1 and Abhd14a 1 0.00 0 0
103 INT324053 Binding of Banf1 and Lemd3 1 0.20 0.15 0
104 INT293868 Binding of GREM1 and OCM 1 0.00 1.11 0
105 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
106 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0
107 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0
108 INT288593 Cav1 Positive_regulation of Binding of Kcnma1 1 0.15 0 0
109 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0
110 INT347155 Mirlet7a-1 Negative_regulation of Smad7 1 0.10 0 0
111 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
112 INT244854 Binding of Lbx1 and Skor1 1 0.31 0 0
113 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0
114 INT302323 Binding of SOST and Wnt2 1 0.02 0.26 0
115 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
116 INT242165 Wnt2 Positive_regulation of Gene_expression of Fzd1 1 0.15 0.26 0
117 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
118 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0
119 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0
120 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
121 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0
122 INT183868 CAV1 Positive_regulation of PAF1 1 0.54 0.41 0
123 INT288591 Cav1 Positive_regulation of Kcnma1 1 0.15 0 0
124 INT264805 Binding of GREM1 and CNNM2 1 0.00 0.24 0
125 INT293981 MYC Negative_regulation of DKK1 1 0.07 0.62 0
126 INT262498 Binding of Aqp1 and Cav1 1 0.03 0.56 0
127 INT298103 Binding of Cav1 and Ca2 1 0.03 0 0
128 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
129 INT315194 Binding of SFRP1 and Slc10a1 1 0.02 8.85 0
130 INT220518 Cav1 Negative_regulation of Akt1 1 0.04 1.02 0
131 INT335882 Dkk1 Negative_regulation of Wnt2 1 0.02 0.15 0
132 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
133 INT242166 Fzd1 Positive_regulation of Positive_regulation of Wnt2 1 0.13 0.24 0
134 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
135 INT310190 Binding of Adcyap1r1 and Smad6 1 0.00 0 0
136 INT288592 Binding of Cav1 and Olfr1012 1 0.01 0 0
137 INT183866 CAV1 Regulation of RHOC 1 0.25 0.2 0
138 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
139 INT183867 Binding of CAV1 and Positive_regulation of Positive_regulation of RHOC 1 0.46 0.1 0
140 INT298104 Ca2 Negative_regulation of Cav1 1 0.04 0.09 0
141 INT315035 Binding of NAE1 and Cav1 1 0.01 0.7 0
142 INT288586 Cav1 Positive_regulation of Regulation of Kcnma1 1 0.21 0 0
143 INT183852 CAV1 Regulation of Positive_regulation of RHOC 1 0.41 0.63 0
144 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
145 INT288558 Binding of CAV1 and KCNMA1 1 0.00 0 0
146 INT288583 Negative_regulation of Binding of Cav1 and Kcnma1 1 0.13 0 0
147 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0
148 INT220526 Binding of Akt1 and Cav1 1 0.03 1.02 0
149 INT288589 Cav1 Regulation of Kcnma1 1 0.19 0.05 0
150 INT315187 Binding of SFRP1 and COPD 1 0.01 4.47 0
151 INT351159 CAV1 Positive_regulation of AKT1 1 0.11 0.87 0
152 INT183854 Regulation of CAV1 Positive_regulation of RHOC 1 0.41 0.26 0
153 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of BMP signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of BMP signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52
2 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
3 INT50767 Positive_regulation of Nanog 14 0.67 3.63 8.56
4 INT28358 Gene_expression of Nanog 25 0.70 3.52 7.85
5 INT197458 Positive_regulation of Sostdc1 11 0.01 3.02 4.87
6 INT111156 Negative_regulation of Dkk1 21 0.58 20.08 4.27
7 INT197459 Gene_expression of Sostdc1 10 0.01 1.04 4.11
8 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
9 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
10 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
11 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
12 INT64825 Negative_regulation of Nanog 8 0.57 2.59 3.47
13 INT148190 Positive_regulation of Transcription of Nanog 1 0.49 0.2 3.17
14 INT122787 Transcription of Nanog 4 0.67 0.78 2.81
15 INT122782 Negative_regulation of Positive_regulation of Nanog 3 0.57 1.15 2.81
16 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
17 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
18 INT27412 Regulation of Nanog 7 0.58 0.81 2.59
19 INT111153 Positive_regulation of Dkk1 13 0.68 10.56 2.58
20 INT188255 Gene_expression of DKK1 19 0.60 12.69 2.39
21 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
22 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
23 INT62692 Localization of Nanog 3 0.73 0.82 1.85
24 INT139475 Negative_regulation of DKK1 14 0.52 9.2 1.76
25 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
26 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
27 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
28 INT176629 Gene_expression of GREM1 9 0.10 6.89 1.66
29 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
30 INT344978 Negative_regulation of Gene_expression of Dkk1 1 0.58 4.38 1.59
31 INT321889 Negative_regulation of Dkk1 2 0.38 5.7 1.42
32 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
33 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
34 INT141862 Binding of Cav1 11 0.36 1.32 1.25
35 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
36 INT150074 Gene_expression of WNT5A 8 0.75 6.3 1.17
37 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
38 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
39 INT165338 Binding of Dkk1 4 0.37 3.64 1.04
40 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
41 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
42 INT47039 Regulation of SFRP1 14 0.62 7.44 0.92
43 INT257893 Negative_regulation of Positive_regulation of Sostdc1 1 0.01 0 0.9
44 INT215518 Negative_regulation of Trim33 2 0.57 0.43 0.88
45 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
46 INT304863 Negative_regulation of Gene_expression of Nanog 4 0.41 0.91 0.84
47 INT165337 Regulation of Dkk1 3 0.44 2.16 0.83
48 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
49 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
50 INT188251 Localization of DKK1 6 0.50 3.26 0.77
51 INT242131 Localization of Dkk1 5 0.79 6 0.76
52 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
53 INT344975 Regulation of Gene_expression of Dkk1 1 0.44 3.44 0.73
54 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
55 INT129882 Positive_regulation of Gene_expression of Dkk1 4 0.69 4.62 0.72
56 INT215519 Protein_catabolism of Trim33 1 0.86 0.39 0.69
57 INT153667 Localization of CAV1 15 0.76 11.92 0.68
58 INT335876 Negative_regulation of Sost 11 0.51 6.77 0.67
59 INT54497 Binding of Nanog 1 0.35 0 0.67
60 INT47038 Gene_expression of SFRP1 14 0.67 9.6 0.63
61 INT62732 Positive_regulation of Gene_expression of Nanog 2 0.45 0.27 0.63
62 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
63 INT165156 Gene_expression of Sostdc1 4 0.59 2.52 0.6
64 INT169167 Positive_regulation of GREM1 1 0.08 1.83 0.6
65 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
66 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
67 INT150075 Positive_regulation of Gene_expression of WNT5A 2 0.67 2.53 0.59
68 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
69 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
70 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
71 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
72 INT244797 Gene_expression of Skor1 1 0.65 0.26 0.48
73 INT86702 Localization of Cav1 8 0.69 0.76 0.47
74 INT135366 Localization of SFRP1 4 0.75 1.82 0.47
75 INT304861 Regulation of Gene_expression of Nanog 3 0.43 0.13 0.46
76 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
77 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
78 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
79 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
80 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
81 INT84326 Protein_catabolism of Nanog 1 0.02 0 0.41
82 INT220506 Binding of Cav1 13 0.45 5.46 0.38
83 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
84 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
85 INT302314 Negative_regulation of SOST 5 0.44 2.22 0.33
86 INT242130 Positive_regulation of Positive_regulation of Dkk1 2 0.49 1.71 0.33
87 INT344976 Positive_regulation of Negative_regulation of Dkk1 1 0.49 1.13 0.33
88 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
89 INT230390 Binding of Sostdc1 1 0.04 0.96 0.31
90 INT344977 Negative_regulation of Localization of Dkk1 2 0.42 2.57 0.3
91 INT184716 Binding of Smad7 2 0.34 0.91 0.29
92 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
93 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
94 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
95 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
96 INT19917 Regulation of DKK1 3 0.24 1.61 0.28
97 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
98 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
99 INT335878 Localization of Sost 3 0.69 1.11 0.22
100 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
101 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
102 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
103 INT242141 Gene_expression of Fzd1 1 0.21 2.5 0.21
104 INT335864 Gene_expression of Sost 4 0.77 2.36 0.2
105 INT114371 Negative_regulation of Tcf7l2 1 0.05 0.7 0.2
106 INT177609 Negative_regulation of GREM1 4 0.06 1.73 0.19
107 INT272889 Negative_regulation of Smad6 2 0.20 1.31 0.19
108 INT264812 Binding of GREM1 1 0.00 0.53 0.19
109 INT335869 Binding of Sost 6 0.32 1.79 0.18
110 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18
111 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
112 INT86697 Negative_regulation of Regulation of Cav1 1 0.41 0 0.18
113 INT344979 Negative_regulation of Gene_expression of DKK1 1 0.17 0.98 0.17
114 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
115 INT242127 Positive_regulation of Localization of Dkk1 1 0.05 0.35 0.17
116 INT344980 Negative_regulation of Localization of DKK1 1 0.17 0.97 0.16
117 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15
118 INT228790 Positive_regulation of Smad7 4 0.41 0.58 0.15
119 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
120 INT214975 Localization of Cav1 7 0.75 2.7 0.13
121 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
122 INT197460 Negative_regulation of Sostdc1 1 0.00 0.24 0.13
123 INT162574 Gene_expression of Wnt5a 7 0.47 0.92 0.1
124 INT282594 Localization of WNT5A 2 0.18 0.89 0.1
125 INT324046 Gene_expression of Lemd3 1 0.67 1.69 0.1
126 INT233483 Regulation of Gene_expression of Wnt5a 1 0.19 0.33 0.1
127 INT165150 Regulation of Sostdc1 1 0.24 0.07 0.09
128 INT302313 Gene_expression of SOST 6 0.67 2.06 0.08
129 INT302317 Positive_regulation of Gene_expression of SOST 4 0.60 1.58 0.08
130 INT188252 Positive_regulation of DKK1 4 0.41 2.94 0.08
131 INT162576 Positive_regulation of Wnt5a 3 0.48 0.71 0.08
132 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
133 INT353267 Negative_regulation of Positive_regulation of Smad7 1 0.25 0.32 0.08
134 INT233462 Regulation of Fzd1 1 0.45 0.33 0.08
135 INT220491 Transcription of Cav1 2 0.54 1.1 0.07
136 INT220500 Positive_regulation of Transcription of Cav1 1 0.16 0.9 0.07
137 INT290078 Regulation of WNT5A 1 0.07 2.3 0.07
138 INT313838 Gene_expression of Fstl3 1 0.61 1.21 0.06
139 INT206866 Positive_regulation of SFRP1 7 0.51 3.97 0.05
140 INT302316 Negative_regulation of Gene_expression of SOST 4 0.51 1.36 0.05
141 INT145370 Transcription of DKK1 3 0.53 1.07 0.05
142 INT185989 Localization of GREM1 2 0.11 2.41 0.05
143 INT287913 Positive_regulation of Gene_expression of SFRP1 2 0.25 2.12 0.05
144 INT220502 Positive_regulation of Positive_regulation of Cav1 1 0.24 0.21 0.05
145 INT329487 Positive_regulation of Negative_regulation of SOST 1 0.45 0.62 0.05
146 INT347149 Localization of Smad7 1 0.67 0 0.05
147 INT315009 Regulation of Phosphorylation of Cav1 1 0.36 0.2 0.05
148 INT335868 Negative_regulation of Gene_expression of Sost 2 0.58 1.12 0.04
149 INT300713 Regulation of Localization of Cav1 2 0.42 1.37 0.04
150 INT172971 Gene_expression of Smad6 2 0.37 1.77 0.04
151 INT302318 Regulation of SOST 2 0.34 0.46 0.04
152 INT311898 Positive_regulation of Gene_expression of Smad6 1 0.33 0.53 0.04
153 INT314252 Transcription of CAV1 1 0.50 0.07 0.04
154 INT321885 Localization of Dkk1 1 0.56 0.87 0.04
155 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
156 INT183878 Negative_regulation of Positive_regulation of CAV1 1 0.41 0.16 0.03
157 INT347119 Localization of FZD1 1 0.68 0.16 0.03
158 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
159 INT353280 Phosphorylation of Smad7 1 0.48 0.06 0.03
160 INT183883 Binding of CAV1 8 0.46 3.89 0
161 INT226288 Negative_regulation of SFRP1 6 0.43 4.45 0
162 INT210256 Positive_regulation of Tcf7l2 2 0.28 1.25 0
163 INT283550 Negative_regulation of Binding of Cav1 2 0.33 0.11 0
164 INT298115 Regulation of Binding of Cav1 1 0.12 0 0
165 INT324047 Binding of Lemd3 1 0.48 3.18 0
166 INT338152 Positive_regulation of Gene_expression of Sost 1 0.69 0.2 0
167 INT313833 Negative_regulation of Gene_expression of Fstl3 1 0.33 0 0
168 INT244799 Negative_regulation of Skor1 1 0.49 0 0
169 INT347148 Regulation of Smad7 1 0.26 0 0
170 INT333344 Transcription of GREM1 1 0.03 0.16 0
171 INT183890 Regulation of Negative_regulation of CAV1 1 0.43 0.38 0
172 INT335880 Regulation of Wnt5a 1 0.32 0.07 0
173 INT288581 Negative_regulation of Binding of CAV1 1 0.03 0 0
174 INT313834 Negative_regulation of Fstl3 1 0.33 0.64 0
175 INT218701 Negative_regulation of Binding of Smad7 1 0.14 0.15 0
176 INT166121 Binding of SMAD7 1 0.30 0.39 0
177 INT315010 Negative_regulation of Transcription of Cav1 1 0.34 0.21 0
178 INT355096 Phosphorylation of GREM1 1 0.02 0.25 0
179 INT300174 Negative_regulation of Gene_expression of NOTCH1 1 0.04 0.53 0
180 INT315189 Binding of SFRP1 1 0.15 2.96 0
181 INT353273 Negative_regulation of Phosphorylation of Smad7 1 0.25 0 0
182 INT242143 Regulation of Gene_expression of Fzd1 1 0.14 0.25 0
183 INT226287 Regulation of Gene_expression of SFRP1 1 0.38 0.37 0
184 INT324043 Localization of Lemd3 1 0.75 0 0
185 INT234247 Negative_regulation of Protein_catabolism of NOTCH1 1 0.05 0 0
186 INT130094 Regulation of Positive_regulation of NOTCH1 1 0.45 0.52 0
187 INT165336 Negative_regulation of Negative_regulation of Dkk1 1 0.33 0 0
188 INT347145 Transcription of Smad7 1 0.68 0 0
189 INT324044 Negative_regulation of Lemd3 1 0.43 2.86 0
190 INT233478 Negative_regulation of Fzd1 1 0.31 0.09 0
191 INT285587 Positive_regulation of Localization of Cav1 1 0.11 0.08 0
192 INT288580 Regulation of Binding of CAV1 1 0.03 0 0
193 INT313837 Regulation of Gene_expression of Fstl3 1 0.21 0 0
194 INT293878 Positive_regulation of Localization of GREM1 1 0.01 0.47 0
195 INT288574 Negative_regulation of Negative_regulation of Cav1 1 0.33 0.06 0
196 INT201624 Regulation of FZD1 1 0.01 0 0
197 INT324048 Positive_regulation of Negative_regulation of Lemd3 1 0.50 0.2 0
198 INT338151 Regulation of Sost 1 0.39 0.16 0
199 INT302315 Localization of SOST 1 0.61 0.11 0
200 INT355082 Positive_regulation of Phosphorylation of GREM1 1 0.01 0.25 0
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