GO:0030546

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Name receptor activator activity
Categary Function
Go Slim No
Go Link GO:0030546
Unique Molecular Interactions 55
Total Molecular Interactions 62
Total Single Events 561
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for receptor activator activity. They are ordered first by their pain relevance and then by number of times they were reported for receptor activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147659 Prkce Positive_regulation of TRPV1 1 0.04 1.42 2.43
2 INT135582 Prok2 Positive_regulation of Localization of Prkce 1 0.06 1.02 1.87
3 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
4 INT147660 Positive_regulation of Prkce Positive_regulation of TRPV1 1 0.04 0.69 1.12
5 INT96905 Plxna3 Regulation of Regulation of Prkce 1 0.18 0.71 1.07
6 INT109842 Prkce Positive_regulation of Localization of Trpv1 1 0.13 1.31 0.91
7 INT110518 Tnf Positive_regulation of Prkce 1 0.26 1.43 0.78
8 INT148454 Gene_expression of Inhbe Positive_regulation of Prkce 1 0.08 0.67 0.69
9 INT154766 Nox1 Positive_regulation of Localization of Prkce 1 0.47 0.45 0.66
10 INT112513 Binding of Prkaca and Prkce 1 0.04 0.4 0.64
11 INT112516 Binding of Prkce and Trib3 1 0.01 0.4 0.64
12 INT144129 Prkce Positive_regulation of Phosphorylation of Gja1 1 0.42 0.48 0.55
13 INT144128 Binding of Gja1 and Prkce 1 0.40 0.5 0.52
14 INT140356 Prkca Regulation of Phosphorylation of Prkce 1 0.18 0.44 0.52
15 INT150833 Esr1 Positive_regulation of Localization of Prkce 1 0.08 0.29 0.51
16 INT215037 Ghrh Regulation of Localization of Igf2 1 0.04 2.12 0.24
17 INT34773 GH1 Regulation of IGF2 1 0.31 0.05 0.22
18 INT92580 IGF2 Positive_regulation of Gene_expression of PTGER2 1 0.07 0.43 0.15
19 INT92583 IGF2 Positive_regulation of Transcription of PTGER2 1 0.07 0.43 0.15
20 INT134614 Prkce Regulation of Trpv1 1 0.30 0.15 0.13
21 INT110107 Acot1 Positive_regulation of Localization of Prkce 1 0.11 0 0.12
22 INT234626 IGFBP3 Regulation of IGF2 1 0.15 1.31 0.1
23 INT354120 Binding of IGF2 and IGFBP5 1 0.01 0.45 0.09
24 INT354124 Binding of IGF2 and IGFBP3 1 0.01 0.45 0.09
25 INT51274 IGF1 Negative_regulation of IGF2 1 0.28 0.13 0.06
26 INT199365 Igf2 Positive_regulation of Phosphorylation of Macf1 1 0.13 1.84 0
27 INT199359 Igf2 Regulation of Macf1 1 0.11 3.11 0
28 INT199361 Regulation of Igf2 Regulation of Macf1 1 0.11 1.59 0
29 INT199367 DST Regulation of Igf2 1 0.03 1.03 0
30 INT300901 Binding of IGF2 and IGF2BP1 1 0.04 0.71 0
31 INT199368 DST Positive_regulation of Gene_expression of Igf2 1 0.04 1.51 0
32 INT199371 DST Regulation of Transcription of Igf2 1 0.05 1.47 0
33 INT202431 Binding of IGF2 and INSRR 1 0.01 0.85 0
34 INT169448 Binding of Prkce and Trpv4 1 0.04 0.08 0
35 INT199360 Igf2 Regulation of Gene_expression of Lyve1 1 0.30 1.13 0
36 INT199363 Igf2 Regulation of Gopc 1 0.15 1.61 0
37 INT199370 DST Regulation of Gene_expression of Igf2 1 0.02 1.07 0
38 INT215205 Binding of Igf2 and Igfbp3 1 0.04 0 0
39 INT141959 Binding of IGFBP3 and Igf2 1 0.01 0.09 0
40 INT300899 IGF2BP3 Positive_regulation of IGF2 1 0.37 1.06 0
41 INT141950 Binding of Igf2 and Mb 1 0.00 0.1 0
42 INT202430 Binding of IGF2 and INS 1 0.16 0.85 0
43 INT300898 IGF2BP3 Regulation of Gene_expression of IGF2 1 0.21 0.38 0
44 INT199362 Igf2 Positive_regulation of Macf1 1 0.11 1.67 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for receptor activator activity. They are ordered first by their pain relevance and then by number of times they were reported in receptor activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT88650 Negative_regulation of Prkce 13 0.57 11.93 11.16
2 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32
3 INT72148 Positive_regulation of Prkce 17 0.68 5.06 9.44
4 INT110104 Localization of Prkce 17 0.79 3.75 6.92
5 INT101497 Phosphorylation of Prkce 9 0.81 2.55 5.59
6 INT91946 Regulation of Prkce 6 0.44 4.13 5.46
7 INT109838 Phosphorylation of Prkce 6 0.67 5.26 4.95
8 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59
9 INT25709 Negative_regulation of Igf2 11 0.56 9.38 3.76
10 INT109840 Localization of Prkce 5 0.74 3.01 3.45
11 INT110100 Negative_regulation of Prkce 5 0.57 0.68 3.16
12 INT9335 Gene_expression of Igf2 18 0.72 12.76 2.78
13 INT128184 Positive_regulation of Positive_regulation of Prkce 4 0.41 1.3 2.64
14 INT9327 Localization of Igf2 8 0.80 5.07 2.36
15 INT25208 Gene_expression of IGF2 43 0.74 30.64 2.31
16 INT128185 Gene_expression of Prkce 4 0.69 1.39 2.23
17 INT57132 Positive_regulation of Igf2 9 0.50 5.15 2.22
18 INT136941 Positive_regulation of Localization of Prkce 3 0.43 1.42 2.06
19 INT124052 Binding of Prkce 2 0.06 2.52 2.03
20 INT91947 Negative_regulation of Negative_regulation of Prkce 1 0.42 0.69 1.3
21 INT110099 Positive_regulation of Localization of Prkce 4 0.68 1.3 1.25
22 INT91949 Regulation of Positive_regulation of Prkce 1 0.44 0.72 1.24
23 INT175520 Gene_expression of Igf2 43 0.78 48.93 1.21
24 INT9324 Negative_regulation of Gene_expression of Igf2 6 0.50 5.12 1.2
25 INT110106 Regulation of Prkce 4 0.44 0.4 1.2
26 INT25710 Regulation of Igf2 6 0.62 3.1 1.17
27 INT110102 Negative_regulation of Localization of Prkce 3 0.49 0.17 1.13
28 INT131238 Negative_regulation of Positive_regulation of Prkce 1 0.41 0.44 1.12
29 INT92588 Positive_regulation of IGF2 8 0.58 4.2 1.07
30 INT135111 Regulation of Gene_expression of Prkce 1 0.51 0.15 0.96
31 INT135115 Regulation of Localization of Prkce 1 0.38 0.15 0.96
32 INT34779 Regulation of IGF2 7 0.38 4.34 0.9
33 INT136944 Positive_regulation of Positive_regulation of Prkce 2 0.46 0.8 0.85
34 INT58245 Regulation of Localization of Igf2 1 0.62 1.27 0.78
35 INT109839 Positive_regulation of Phosphorylation of Prkce 1 0.18 1.27 0.71
36 INT154761 Positive_regulation of Gene_expression of Prkce 1 0.44 0.5 0.7
37 INT154762 Negative_regulation of Phosphorylation of Prkce 1 0.38 0.48 0.69
38 INT34778 Localization of IGF2 5 0.62 4.78 0.59
39 INT277644 Negative_regulation of Localization of Igf2 1 0.02 0.69 0.56
40 INT152068 Regulation of Gene_expression of Prkce 1 0.05 0.74 0.56
41 INT136942 Negative_regulation of Positive_regulation of Prkce 1 0.39 0.66 0.48
42 INT70893 Positive_regulation of Gene_expression of IGF2 5 0.67 6.13 0.44
43 INT9328 Regulation of Gene_expression of Igf2 1 0.39 0.91 0.42
44 INT199340 Localization of Igf2 4 0.75 4.47 0.39
45 INT48617 Negative_regulation of IGF2 4 0.25 0.22 0.36
46 INT57131 Negative_regulation of Positive_regulation of Igf2 1 0.36 0.67 0.35
47 INT199358 Negative_regulation of Gene_expression of Igf2 3 0.43 4.48 0.3
48 INT202435 Transcription of IGF2 3 0.58 2.44 0.29
49 INT9329 Transcription of Igf2 2 0.58 1.28 0.29
50 INT215027 Regulation of Localization of Igf2 1 0.07 1.71 0.24
51 INT140351 Binding of Prkce 2 0.28 0.32 0.22
52 INT169685 Regulation of Positive_regulation of Prkce 1 0.61 0.36 0.22
53 INT199349 Regulation of Gene_expression of Igf2 4 0.50 4.56 0.15
54 INT118235 Positive_regulation of Igf2 9 0.70 10.05 0.12
55 INT76311 Binding of Igf2 2 0.44 1.91 0.12
56 INT199357 Negative_regulation of Igf2 1 0.38 1.91 0.09
57 INT199337 Binding of Igf2 1 0.37 1.55 0.09
58 INT175512 Positive_regulation of Gene_expression of Igf2 16 0.70 22.75 0.08
59 INT185028 Binding of IGF2 4 0.46 1.72 0.07
60 INT51277 Negative_regulation of Gene_expression of IGF2 1 0.25 0.07 0.06
61 INT92591 Negative_regulation of Positive_regulation of IGF2 1 0.28 0.45 0.06
62 INT300903 Negative_regulation of Localization of IGF2 1 0.40 1.45 0.05
63 INT300907 Negative_regulation of Transcription of IGF2 1 0.29 1.44 0.05
64 INT199347 Transcription of Igf2 1 0.72 1.41 0
65 INT353186 Positive_regulation of Gene_expression of Igf2 1 0.37 0.08 0
66 INT202433 Positive_regulation of Transcription of IGF2 1 0.42 0.55 0
67 INT199353 Positive_regulation of Positive_regulation of Igf2 1 0.50 1.35 0
68 INT169684 Positive_regulation of Phosphorylation of Prkce 1 0.49 0.05 0
69 INT199355 Negative_regulation of Positive_regulation of Igf2 1 0.43 0.86 0
70 INT300911 Regulation of Gene_expression of IGF2 1 0.31 0.38 0
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