GO:0030574

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Name collagen catabolic process
Categary Process
Go Slim No
Go Link GO:0030574
Unique Molecular Interactions 605
Total Molecular Interactions 771
Total Single Events 7421
Pain Genes Associated 31

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for collagen catabolic process. They are ordered first by their pain relevance and then by number of times they were reported for collagen catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT215943 Binding of Mmp14 and Timp2 1 0.21 1.59 3.33
2 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
3 INT247601 Binding of PEPD and SCN9A 1 0.15 2.26 2.27
4 INT243043 Binding of Mmp9 and Timp1 1 0.05 0.25 1.86
5 INT205152 Binding of CD44 and MMP9 23 0.35 17.13 1.85
6 INT192161 Mmp14 Positive_regulation of Mmp2 2 0.19 1.23 1.81
7 INT102160 Binding of Mmp2 and Mmp9 3 0.28 2.87 1.75
8 INT168612 Negative_regulation of Nos1 Negative_regulation of Positive_regulation of Mmp9 1 0.23 0.45 1.62
9 INT168607 Negative_regulation of Nos1 Negative_regulation of Mmp9 1 0.23 0.45 1.61
10 INT168609 Binding of Itgb1 and Mmp9 1 0.02 0.41 1.58
11 INT168611 Binding of Mmp9 and Ndor1 1 0.29 0.41 1.57
12 INT168608 Binding of Grin2b and Mmp9 1 0.22 0.41 1.57
13 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
14 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
15 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
16 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
17 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
18 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
19 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
20 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
21 INT202040 CAMK2N2 Negative_regulation of MMP7 1 0.00 0.73 1.24
22 INT187174 RPS3AP9 Negative_regulation of MMP2 1 0.00 0.9 1.22
23 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
24 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
25 INT187176 Binding of BSG and MMP1 1 0.09 1.18 1.08
26 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
27 INT120313 Gnrhr Negative_regulation of Mmp2 1 0.03 0.85 1.07
28 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
29 INT144069 Positive_regulation of TRPV1 Positive_regulation of Gene_expression of MMP1 1 0.43 1.35 1.03
30 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97
31 INT171264 TNF Positive_regulation of MMP1 2 0.10 2.05 0.95
32 INT351311 Has1 Regulation of Gene_expression of MMP3 1 0.11 1.15 0.95
33 INT266659 Binding of MMP9 and MOCS1 1 0.01 1.71 0.94
34 INT250868 Fgf8 Positive_regulation of Gene_expression of Mmp3 1 0.15 1.73 0.93
35 INT161455 Mmp7 Positive_regulation of Egfr 1 0.03 0.19 0.92
36 INT243044 Mmp8 Regulation of Mmp9 1 0.05 1.45 0.91
37 INT121700 IL12RB1 Positive_regulation of Gene_expression of MMP1 1 0.06 0.22 0.9
38 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
39 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
40 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
41 INT109103 MMP2 Positive_regulation of INS 1 0.33 1.07 0.89
42 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
43 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
44 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85
45 INT190165 MMP12 Positive_regulation of MMP2 1 0.13 0.72 0.85
46 INT260894 CRH Regulation of Localization of MMP3 1 0.21 0.36 0.85
47 INT192158 Binding of Mmp2 and Mmp9 1 0.21 0.94 0.83
48 INT106808 RECK Negative_regulation of MMP2 1 0.40 0.5 0.83
49 INT309001 Ins1 Positive_regulation of Mmp9 1 0.20 1.96 0.83
50 INT196525 Binding of MMP2 and MMP9 2 0.32 2.49 0.78
51 INT102163 Binding of TNF and Mmp9 1 0.12 0.88 0.78
52 INT102161 Binding of TNF and Mmp2 1 0.10 0.88 0.78
53 INT102159 Binding of Adam17 and Mmp2 1 0.18 0.87 0.77
54 INT26497 TNF Positive_regulation of Gene_expression of MMP2 1 0.44 1.5 0.75
55 INT150268 MMP8 Regulation of Transcription of SFTPA1 1 0.05 0.43 0.75
56 INT260895 CRH Regulation of MMP1 1 0.11 0.31 0.74
57 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
58 INT162241 Binding of COL7A1 and MMP13 2 0.03 0.86 0.73
59 INT162240 Binding of COL7A1 and MMP1 1 0.03 0.86 0.73
60 INT162239 Binding of COL7A1 and MMP8 1 0.04 0.86 0.73
61 INT121697 IL4I1 Positive_regulation of Gene_expression of MMP3 1 0.06 0.27 0.7
62 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7
63 INT224678 Binding of Mmp14 and Mmp23 1 0.00 0.85 0.69
64 INT346225 Binding of PRTN3 and Flg 1 0.01 1.74 0.69
65 INT263049 Positive_regulation of Binding of Mmp2 and Mmp9 1 0.35 0.83 0.69
66 INT185802 Binding of MMP7 and SPP1 1 0.33 1.71 0.68
67 INT157935 Negative_regulation of TRPV1 Negative_regulation of Gene_expression of MMP1 1 0.42 0.1 0.68
68 INT152298 Mmp9 Negative_regulation of Tsc22d1 1 0.13 0.16 0.66
69 INT152299 Mmp2 Negative_regulation of Tsc22d1 1 0.16 0.16 0.66
70 INT152296 Regulation of Mmp9 Negative_regulation of Tsc22d1 1 0.08 0.16 0.66
71 INT152297 Mmp2 Negative_regulation of Mmp9 1 0.39 0.16 0.65
72 INT224683 Mmp14 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
73 INT224693 Timp2 Positive_regulation of Binding of Mmp9 1 0.01 0.81 0.65
74 INT149899 Ihh Positive_regulation of Mmp7 1 0.04 1.69 0.65
75 INT224684 Binding of Mmp14 and Mmp9 1 0.01 0.81 0.64
76 INT99602 ZNF398 Negative_regulation of MMP2 1 0.14 0.85 0.63
77 INT182266 EDN1 Positive_regulation of Gene_expression of MMP13 1 0.35 2.03 0.63
78 INT314051 THL Negative_regulation of Localization of Mmp2 1 0.14 1.1 0.62
79 INT302469 F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.82 0.62
80 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61
81 INT95435 Il1a Positive_regulation of Positive_regulation of Mmp3 1 0.59 0.25 0.61
82 INT95436 Il1a Positive_regulation of Mmp3 1 0.59 0.25 0.61
83 INT95434 Mmp9 Positive_regulation of Positive_regulation of Il1a 1 0.42 0.23 0.61
84 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6
85 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6
86 INT95432 Il1a Positive_regulation of Positive_regulation of Mmp9 1 0.37 0.25 0.6
87 INT95430 Mmp9 Positive_regulation of Mmp3 1 0.38 0.24 0.6
88 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6
89 INT178087 EDN1 Positive_regulation of MMP13 2 0.23 1.58 0.59
90 INT316831 CCL5 Positive_regulation of Gene_expression of MMP2 1 0.02 0.51 0.59
91 INT202038 MMP9 Positive_regulation of IL8 1 0.05 0.29 0.59
92 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58
93 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
94 INT302833 Gene_expression of Mir155 Negative_regulation of Gene_expression of Mmp3 1 0.03 1 0.57
95 INT342619 Mmp2 Negative_regulation of Timp2 1 0.42 1.48 0.57
96 INT157934 TRPV1 Positive_regulation of Positive_regulation of MMP1 1 0.45 0.07 0.57
97 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57
98 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57
99 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
100 INT203105 MMP3 Negative_regulation of Gene_expression of IL10 1 0.06 0.69 0.56
101 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56
102 INT173555 TIMP1 Negative_regulation of MMP7 1 0.01 0 0.56
103 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
104 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
105 INT173557 TIMP1 Negative_regulation of MMP3 1 0.02 0 0.56
106 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55
107 INT114029 Binding of ALB and Mmp3 1 0.01 0.31 0.55
108 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55
109 INT114028 Negative_regulation of Binding of ALB and Mmp3 1 0.01 0.31 0.55
110 INT316737 Il1 Positive_regulation of Mmp1a 1 0.01 0.64 0.54
111 INT282711 Binding of Csf2 and Mmp9 1 0.16 1.35 0.54
112 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
113 INT316738 Il1 Positive_regulation of Mmp3 1 0.02 0.63 0.54
114 INT196522 Binding of MMP1 and TIMP1 1 0.39 0.29 0.53
115 INT314043 THL Negative_regulation of Mmp2 1 0.22 2.11 0.53
116 INT192162 Furin Positive_regulation of Mmp14 1 0.10 0.79 0.53
117 INT150790 ZNF398 Positive_regulation of Localization of MMP2 1 0.04 0.51 0.53
118 INT194915 Csf2 Positive_regulation of Gene_expression of Mmp1a 1 0.01 0.85 0.52
119 INT192159 Mmp14 Regulation of Protein_catabolism of Col1a1 1 0.02 1.01 0.52
120 INT205728 Mmp9 Positive_regulation of Gene_expression of Mmp3 1 0.29 0 0.52
121 INT196521 Binding of MMP2 and TIMP2 1 0.30 0.68 0.52
122 INT194916 Kitl Positive_regulation of Gene_expression of Mmp1a 1 0.00 0.85 0.52
123 INT282713 Binding of MUC5AC and Mmp9 1 0.02 1.27 0.52
124 INT205727 Mmp3 Positive_regulation of Gene_expression of Mmp9 1 0.29 0 0.52
125 INT150785 THBS1 Negative_regulation of MMP2 1 0.10 0.5 0.52
126 INT144070 Gene_expression of TRPV1 Positive_regulation of Positive_regulation of MMP1 1 0.43 0.68 0.52
127 INT144072 Gene_expression of TRPV1 Positive_regulation of MMP1 1 0.43 0.68 0.52
128 INT150792 THBS3 Negative_regulation of MMP2 1 0.11 0.49 0.51
129 INT196527 Positive_regulation of Binding of MMP1 and MMP2 1 0.44 0.74 0.51
130 INT196524 Binding of MMP1 and MMP9 1 0.31 0.74 0.51
131 INT196519 Positive_regulation of Binding of MMP1 and MMP9 1 0.42 0.74 0.51
132 INT196520 Binding of MMP1 and MMP2 1 0.33 0.74 0.51
133 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5
134 INT150921 ZNF398 Negative_regulation of Gene_expression of Mmp2 1 0.00 0.46 0.5
135 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5
136 INT297152 Binding of PRTN3 and SNRNP70 1 0.40 1.27 0.5
137 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5
138 INT185800 SPP1 Negative_regulation of Gene_expression of MMP1 1 0.26 1.03 0.49
139 INT224675 S100a4 Positive_regulation of Mmp3 1 0.04 0.94 0.48
140 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48
141 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48
142 INT203104 MMP3 Positive_regulation of Gene_expression of IFN1@ 1 0.25 0.33 0.48
143 INT127664 Negative_regulation of PDE4A Negative_regulation of MMP9 1 0.37 0.76 0.48
144 INT277063 CRP Positive_regulation of Gene_expression of MMP10 1 0.39 1.53 0.48
145 INT127665 Negative_regulation of PDE4A Negative_regulation of Transcription of MMP9 1 0.37 0.76 0.48
146 INT173596 Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
147 INT173598 Negative_regulation of Binding of MMP3 and Mmp13 1 0.06 0.84 0.48
148 INT277065 CRP Positive_regulation of Gene_expression of MMP1 1 0.41 1.52 0.47
149 INT250858 Mmp3 Regulation of Protein_catabolism of Ecm1 1 0.01 1.11 0.47
150 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
151 INT303445 Mmp3 Positive_regulation of Mmp9 1 0.01 1.19 0.47
152 INT138152 IL6 Positive_regulation of Transcription of Mmp2 1 0.00 0.23 0.46
153 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
154 INT138159 IL6 Positive_regulation of Gene_expression of Mmp3 1 0.00 0.23 0.46
155 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
156 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
157 INT138160 IL1B Positive_regulation of Gene_expression of Mmp3 1 0.03 0.23 0.46
158 INT224674 S100a4 Positive_regulation of Gene_expression of Mmp9 1 0.03 0.85 0.45
159 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45
160 INT224686 S100a4 Positive_regulation of Gene_expression of Mmp13 1 0.05 0.85 0.45
161 INT224692 S100a4 Positive_regulation of Gene_expression of Mmp1a 1 0.02 0.85 0.45
162 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45
163 INT314044 THL Negative_regulation of Transcription of Mmp9 1 0.20 0.81 0.45
164 INT218706 Olr811 Positive_regulation of MMP1 1 0.00 3.16 0.45
165 INT314050 THL Negative_regulation of Transcription of Mmp2 1 0.16 0.81 0.44
166 INT335996 Mmp8 Regulation of Protein_catabolism of MIP 1 0.44 1.06 0.43
167 INT196348 PTGER2 Negative_regulation of Negative_regulation of MMP2 1 0.01 0.29 0.43
168 INT226070 Binding of CRP and MMP9 1 0.51 1.13 0.42
169 INT314042 THL Negative_regulation of Gene_expression of Mmp2 1 0.19 2.97 0.42
170 INT133002 Mmp9 Regulation of Negative_regulation of Igfbp3 1 0.26 0.39 0.42
171 INT251015 OLR1 Regulation of Protein_catabolism of MMP3 1 0.03 0.91 0.4
172 INT181995 TIMP1 Negative_regulation of Mmp9 1 0.01 1.38 0.4
173 INT314046 THL Negative_regulation of Localization of Mmp9 1 0.13 0.95 0.39
174 INT226072 Binding of MMP9 and SHBG 1 0.15 1.02 0.39
175 INT312086 ELANE Positive_regulation of MMP13 1 0.13 0.64 0.39
176 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38
177 INT346227 Binding of PRTN3 and Vim 1 0.01 0.93 0.38
178 INT185811 SPP1 Positive_regulation of MMP3 1 0.14 0.83 0.38
179 INT179851 Il11 Positive_regulation of Mmp2 1 0.04 0 0.38
180 INT185814 Binding of MMP3 and SPP1 1 0.15 0.83 0.38
181 INT278960 ZEB1 Negative_regulation of MMP3 1 0.00 1.05 0.38
182 INT218707 Mmp1a Negative_regulation of MMP1 1 0.00 2.03 0.38
183 INT278943 ZEB1 Negative_regulation of Gene_expression of MMP3 1 0.00 1.05 0.38
184 INT342622 Binding of MMP14 and Mmp2 1 0.39 1.15 0.37
185 INT185804 MMP2 Positive_regulation of SPP1 1 0.15 0.88 0.37
186 INT172023 Binding of FN1 and PRTN3 1 0.00 1.05 0.37
187 INT185795 MMP7 Positive_regulation of SPP1 1 0.38 0.81 0.37
188 INT342617 Binding of Col18a1 and Mmp2 1 0.11 1.15 0.37
189 INT185798 SPP1 Positive_regulation of Gene_expression of MMP2 1 0.26 0.87 0.37
190 INT179839 Il11 Negative_regulation of Mmp1a 1 0.03 0 0.37
191 INT185807 SPP1 Positive_regulation of MMP7 1 0.56 0.79 0.36
192 INT198970 GAPDH Negative_regulation of ADAMTS3 1 0.47 0 0.35
193 INT288164 Jun Regulation of Gene_expression of Mmp13 1 0.02 0.41 0.35
194 INT302466 Positive_regulation of F2 Positive_regulation of Gene_expression of MMP9 1 0.01 1.1 0.35
195 INT288167 Ugcg Negative_regulation of Gene_expression of Mmp13 1 0.06 0.46 0.35
196 INT264521 PTGDS Negative_regulation of Positive_regulation of MMP1 1 0.06 1.42 0.34
197 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33
198 INT99603 ZNF398 Regulation of Transcription of MMP2 1 0.15 0.44 0.33
199 INT149895 Ihh Regulation of Localization of Mmp7 1 0.03 0.98 0.33
200 INT326089 Gopc Positive_regulation of Mmp9 1 0.03 0.63 0.33

Single Events

The table below shows the top 100 pain related interactions that have been reported for collagen catabolic process. They are ordered first by their pain relevance and then by number of times they were reported in collagen catabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81
2 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72
3 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01
4 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9
5 INT115384 Positive_regulation of Mmp9 121 0.68 94.74 43.02
6 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78
7 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55
8 INT99610 Localization of MMP9 126 0.79 48.46 32.67
9 INT29503 Gene_expression of Mmp2 95 0.77 56.92 31.68
10 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04
11 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71
12 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
13 INT73047 Positive_regulation of MMP9 133 0.68 73.22 26.42
14 INT140193 Gene_expression of Mmp3 58 0.71 49.65 25.4
15 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89
16 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25
17 INT34487 Localization of MMP2 56 0.81 31.41 23.61
18 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57
19 INT74682 Positive_regulation of Mmp2 72 0.69 40.46 21.73
20 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72
21 INT170313 Gene_expression of Mmp1a 50 0.65 38.53 21.36
22 INT50814 Positive_regulation of Mmp2 72 0.68 51.37 20.42
23 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
24 INT93663 Positive_regulation of MMP1 72 0.67 33.38 19.86
25 INT132997 Localization of Mmp9 59 0.80 45.9 17.61
26 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1
27 INT99898 Gene_expression of Mmp14 37 0.56 28.54 16.39
28 INT26314 Positive_regulation of MMP3 48 0.67 22.14 16.17
29 INT103245 Positive_regulation of Gene_expression of MMP9 64 0.68 36.86 15.7
30 INT81486 Localization of MMP3 31 0.81 12.94 15.21
31 INT26501 Positive_regulation of Gene_expression of MMP2 51 0.67 39 15.16
32 INT103210 Localization of MMP1 43 0.78 12.15 15.13
33 INT113606 Positive_regulation of Gene_expression of Mmp9 46 0.64 44 15.07
34 INT12891 Negative_regulation of MMP3 41 0.58 17.99 15.06
35 INT74587 Gene_expression of MMP8 31 0.78 24.4 14.91
36 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91
37 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31
38 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36
39 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
40 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73
41 INT68976 Positive_regulation of Gene_expression of Mmp9 34 0.42 28.21 11.28
42 INT86291 Negative_regulation of Mmp2 33 0.57 20.38 10.76
43 INT74681 Positive_regulation of Gene_expression of Mmp2 23 0.55 15.58 10.74
44 INT34485 Negative_regulation of Localization of MMP2 17 0.50 9.96 10.49
45 INT89282 Regulation of MMP9 39 0.60 25.45 10.34
46 INT107606 Negative_regulation of MMP1 38 0.42 11.94 10.01
47 INT113605 Negative_regulation of Gene_expression of Mmp9 25 0.41 22.92 9.98
48 INT95632 Positive_regulation of MMP8 26 0.70 10.06 9.96
49 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79
50 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71
51 INT102987 Regulation of MMP3 23 0.60 9.35 9.54
52 INT26502 Negative_regulation of Gene_expression of MMP2 39 0.58 21.45 9.42
53 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37
54 INT48233 Negative_regulation of Gene_expression of MMP1 34 0.58 12.94 9.08
55 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93
56 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
57 INT111903 Regulation of Mmp2 9 0.61 3.95 7.98
58 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88
59 INT74629 Gene_expression of Mmp7 17 0.55 12.78 7.58
60 INT43727 Negative_regulation of Gene_expression of MMP3 16 0.40 4.81 7.18
61 INT111398 Localization of Mmp2 37 0.76 23.78 7.17
62 INT168381 Positive_regulation of Mmp3 24 0.58 19.12 7.03
63 INT168600 Binding of Mmp9 14 0.44 12.79 6.92
64 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79
65 INT16997 Binding of PRTN3 34 0.48 33.44 6.45
66 INT155780 Gene_expression of Mmp8 19 0.77 15.85 6.33
67 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27
68 INT95607 Regulation of MMP1 19 0.60 7.86 6.18
69 INT140503 Negative_regulation of Gene_expression of Mmp3 7 0.44 5.93 6.08
70 INT108628 Regulation of MMP2 27 0.60 14.85 6.06
71 INT152293 Regulation of Mmp9 9 0.49 6.57 6.01
72 INT123551 Regulation of Mmp2 17 0.57 11.6 6
73 INT87468 Negative_regulation of Mmp2 24 0.57 10.79 5.55
74 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54
75 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47
76 INT90202 Protein_catabolism of MMP2 15 0.94 7.47 5.41
77 INT138157 Regulation of Mmp3 12 0.54 6.12 5.36
78 INT21956 Negative_regulation of Mmp7 12 0.34 7.32 5.34
79 INT95631 Positive_regulation of Gene_expression of MMP8 16 0.50 13.75 5.12
80 INT107242 Binding of MMP3 14 0.47 12.06 5.11
81 INT90374 Positive_regulation of Positive_regulation of MMP2 14 0.50 10.12 5.08
82 INT51983 Negative_regulation of Prtn3 23 0.34 12.54 5
83 INT1285 Localization of Mmp13 12 0.78 8.98 4.93
84 INT102237 Positive_regulation of Gene_expression of MMP3 22 0.44 7.77 4.71
85 INT29502 Localization of Mmp2 18 0.79 3.49 4.64
86 INT89791 Transcription of Mmp3 7 0.33 2.28 4.64
87 INT220861 Positive_regulation of Mmp8 14 0.50 12.21 4.6
88 INT12324 Positive_regulation of PRTN3 26 0.70 18.82 4.55
89 INT160914 Positive_regulation of Positive_regulation of Mmp9 7 0.57 4.69 4.52
90 INT67279 Localization of PRTN3 11 0.50 14.18 4.3
91 INT129964 Negative_regulation of MMP13 23 0.55 6.48 4.21
92 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18
93 INT99608 Transcription of MMP9 18 0.65 9.67 4.11
94 INT82871 Protein_catabolism of MMP1 13 0.96 10.71 4.09
95 INT160915 Regulation of Mmp9 16 0.35 10.25 4.07
96 INT144302 Protein_catabolism of MMP3 7 0.86 7.43 3.98
97 INT220047 Negative_regulation of Gene_expression of Mmp3 4 0.29 5.93 3.95
98 INT133312 Binding of MMP9 25 0.42 16.79 3.83
99 INT140186 Positive_regulation of Gene_expression of Mmp3 7 0.55 6.04 3.82
100 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79
101 INT132994 Positive_regulation of Localization of Mmp9 12 0.42 9.4 3.75
102 INT123883 Positive_regulation of Gene_expression of Mmp3 16 0.60 4.42 3.74
103 INT180922 Negative_regulation of Mmp8 4 0.43 8.35 3.72
104 INT94431 Transcription of MMP1 14 0.56 4.1 3.66
105 INT149614 Localization of MMP13 13 0.81 6.12 3.65
106 INT173849 Positive_regulation of Localization of MMP3 7 0.49 4.6 3.65
107 INT32464 Regulation of Mmp13 12 0.44 6.46 3.61
108 INT161206 Negative_regulation of Localization of Mmp9 10 0.59 9.68 3.59
109 INT129960 Negative_regulation of Gene_expression of MMP13 19 0.53 7.17 3.55
110 INT57439 Regulation of MMP8 6 0.62 2.2 3.54
111 INT116281 Negative_regulation of Gene_expression of Mmp13 15 0.41 9.96 3.41
112 INT181001 Regulation of PRTN3 5 0.18 6.07 3.39
113 INT68974 Localization of Mmp9 10 0.80 4.84 3.35
114 INT172689 Localization of Mmp3 15 0.68 5.52 3.32
115 INT17511 Negative_regulation of PRTN3 19 0.41 12 3.3
116 INT192298 Negative_regulation of MMP7 7 0.27 3.71 3.29
117 INT179456 Negative_regulation of Mmp3 8 0.39 5.95 3.26
118 INT215926 Regulation of Gene_expression of Mmp14 1 0.45 5.33 3.15
119 INT5363 Negative_regulation of PEPD 11 0.56 6.49 3.11
120 INT106037 Gene_expression of PEPD 10 0.75 4.18 3.11
121 INT105985 Transcription of Mmp9 11 0.66 8.55 3.02
122 INT138141 Transcription of Mmp2 10 0.64 6.52 2.99
123 INT140401 Binding of PEPD 3 0.47 2.22 2.97
124 INT170324 Negative_regulation of Gene_expression of Mmp1a 8 0.13 6.28 2.94
125 INT102233 Gene_expression of MMP7 40 0.76 15.78 2.93
126 INT58527 Gene_expression of Prtn3 20 0.71 15.99 2.9
127 INT178108 Positive_regulation of MMP7 11 0.56 7.31 2.85
128 INT123139 Binding of Mmp3 7 0.37 1.98 2.84
129 INT170305 Regulation of Gene_expression of Mmp9 11 0.33 5.7 2.8
130 INT220858 Positive_regulation of Mmp1a 15 0.38 9.11 2.77
131 INT106468 Regulation of Gene_expression of MMP2 11 0.50 3.53 2.77
132 INT104474 Gene_expression of Mmp8 15 0.71 3.1 2.76
133 INT172797 Negative_regulation of Mmp1a 8 0.24 6.47 2.74
134 INT184257 Positive_regulation of Gene_expression of Mmp8 7 0.49 6.32 2.74
135 INT143952 Regulation of Gene_expression of MMP9 14 0.53 10.16 2.73
136 INT99895 Positive_regulation of Mmp14 10 0.58 6.64 2.72
137 INT185898 Gene_expression of MMP10 8 0.49 5.36 2.68
138 INT194892 Regulation of Mmp1a 5 0.22 4.93 2.67
139 INT243033 Localization of Mmp8 8 0.65 5.59 2.52
140 INT129961 Regulation of Gene_expression of MMP1 15 0.46 4.88 2.51
141 INT99897 Positive_regulation of Gene_expression of Mmp14 7 0.36 6.33 2.51
142 INT151309 Positive_regulation of Positive_regulation of MMP3 5 0.60 2.62 2.5
143 INT103603 Negative_regulation of Gene_expression of Mmp2 16 0.51 12.29 2.47
144 INT183810 Positive_regulation of Positive_regulation of MMP9 9 0.52 4.15 2.46
145 INT168603 Negative_regulation of Positive_regulation of Mmp9 3 0.37 2.32 2.42
146 INT338117 Negative_regulation of Transcription of Mmp3 1 0.09 1.01 2.4
147 INT173511 Localization of Mmp1a 4 0.21 2.73 2.39
148 INT120124 Transcription of MMP3 9 0.69 2.15 2.38
149 INT55736 Transcription of MMP2 11 0.68 5.78 2.28
150 INT74628 Positive_regulation of Mmp7 8 0.25 4.19 2.27
151 INT173850 Negative_regulation of Localization of MMP3 3 0.48 3.32 2.25
152 INT121706 Negative_regulation of Positive_regulation of MMP3 4 0.38 2.68 2.19
153 INT180923 Negative_regulation of Localization of Mmp2 6 0.46 7.84 2.17
154 INT152286 Regulation of Gene_expression of Mmp9 5 0.36 3.95 2.15
155 INT93718 Protein_catabolism of Mmp3 9 0.73 4.32 2.11
156 INT263046 Negative_regulation of Gene_expression of Mmp2 7 0.34 5.98 2.09
157 INT125246 Negative_regulation of Positive_regulation of Mmp9 5 0.27 5.34 2.09
158 INT120106 Negative_regulation of Mmp13 8 0.51 2.25 2.08
159 INT116280 Transcription of Mmp13 11 0.67 6.52 2.06
160 INT172554 Positive_regulation of Gene_expression of Mmp1a 7 0.16 4.48 2.05
161 INT145235 Protein_catabolism of Mmp13 3 0.89 2.46 2.03
162 INT185829 Negative_regulation of Positive_regulation of MMP2 7 0.40 4.93 2.02
163 INT103244 Protein_catabolism of MMP9 12 0.72 11.81 2.01
164 INT121707 Negative_regulation of Positive_regulation of MMP1 4 0.37 3.1 2.01
165 INT46332 Binding of Mmp2 10 0.34 5.63 2
166 INT215914 Localization of Mmp14 4 0.59 2.26 1.98
167 INT130728 Binding of MMP1 14 0.47 4.7 1.95
168 INT102158 Protein_catabolism of Mmp9 7 0.65 5.43 1.91
169 INT108393 Positive_regulation of Localization of MMP1 5 0.40 0.85 1.91
170 INT192295 Protein_catabolism of MMP7 10 0.86 2.68 1.86
171 INT243030 Binding of Mmp8 1 0.10 2.4 1.82
172 INT91396 Positive_regulation of Negative_regulation of MMP2 3 0.33 0.97 1.8
173 INT182295 Regulation of MMP13 6 0.27 3.33 1.77
174 INT152292 Regulation of Gene_expression of Mmp2 6 0.61 3.46 1.76
175 INT142637 Positive_regulation of Gene_expression of PRTN3 8 0.46 6.23 1.75
176 INT150275 Localization of MMP8 5 0.68 3.57 1.74
177 INT168599 Phosphorylation of Mmp9 2 0.71 1.09 1.73
178 INT192152 Negative_regulation of Mmp14 3 0.24 1.69 1.72
179 INT125249 Negative_regulation of Gene_expression of Mmp7 4 0.08 3.43 1.71
180 INT215921 Regulation of Mmp14 1 0.33 2.8 1.7
181 INT47889 Binding of MMP2 9 0.41 6.37 1.68
182 INT168601 Negative_regulation of Phosphorylation of Mmp9 1 0.50 0.45 1.66
183 INT74586 Negative_regulation of MMP8 6 0.27 1.68 1.64
184 INT173510 Positive_regulation of Localization of Mmp1a 4 0.13 2.55 1.62
185 INT86294 Regulation of Gene_expression of Mmp2 3 0.60 1.12 1.62
186 INT133443 Transcription of Mmp2 8 0.69 2.48 1.61
187 INT141147 Negative_regulation of Gene_expression of Mmp13 5 0.12 1.37 1.59
188 INT245259 Localization of Mmp3 6 0.68 4.49 1.58
189 INT186724 Negative_regulation of Transcription of MMP9 5 0.37 1.59 1.57
190 INT34486 Regulation of Localization of MMP2 4 0.35 2.19 1.54
191 INT176468 Transcription of Mmp14 3 0.52 2.47 1.51
192 INT295688 Positive_regulation of Regulation of MMP9 1 0.14 0.67 1.51
193 INT120111 Regulation of Mmp13 4 0.29 2.65 1.48
194 INT102989 Regulation of Gene_expression of MMP3 10 0.53 3.29 1.47
195 INT136720 Gene_expression of PRSS2 6 0.50 4.99 1.43
196 INT133294 Regulation of Mmp7 4 0.09 2.03 1.43
197 INT181872 Regulation of Localization of PRTN3 1 0.09 1.98 1.41
198 INT86292 Positive_regulation of Positive_regulation of Mmp2 4 0.46 3.09 1.4
199 INT129963 Regulation of Gene_expression of MMP13 8 0.42 2.84 1.39
200 INT109105 Positive_regulation of Protein_catabolism of MMP2 3 0.46 1.98 1.38
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