GO:0030643

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Name cellular phosphate ion homeostasis
Categary Process
Go Slim No
Go Link GO:0030643
Unique Molecular Interactions 56
Total Molecular Interactions 98
Total Single Events 328
Pain Genes Associated 6

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cellular phosphate ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported for cellular phosphate ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107602 Binding of OPLL and Enpp1 1 0.15 1.12 0.76
2 INT225775 Enpp1 Positive_regulation of Ppi-rs 1 0.06 2.49 0.44
3 INT130975 Binding of ASIC3 and Slc9a3r1 1 0.06 0.26 0.43
4 INT130974 Slc9a3r1 Positive_regulation of ASIC3 1 0.08 0.29 0.36
5 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29
6 INT225776 Enpp1 Positive_regulation of Positive_regulation of Ppi-rs 1 0.08 1.67 0.28
7 INT225784 Il1 Negative_regulation of Gene_expression of Enpp1 1 0.08 0.99 0.28
8 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21
9 INT319971 App Regulation of Enpp1 1 0.02 0.72 0.21
10 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18
11 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17
12 INT256987 Binding of Cd81 and Slc9a3r1 1 0.43 0.06 0.17
13 INT319974 App Negative_regulation of Enpp1 1 0.02 0.58 0.16
14 INT118257 Binding of ENPP1 and SUGT1 1 0.00 0.87 0.16
15 INT319972 App Negative_regulation of Gene_expression of Enpp1 1 0.02 1.87 0.15
16 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13
17 INT225783 Enpp1 Regulation of Ppi-rs 1 0.07 0.68 0.13
18 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13
19 INT238036 Binding of ENPP1 and OPLL 1 0.27 0.66 0.12
20 INT225805 Binding of SNRNP70 and Enpp1 1 0.42 1.43 0.09
21 INT225790 Il1 Regulation of Gene_expression of Enpp1 1 0.07 0.43 0.05
22 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04
23 INT225808 SNRNP70 Regulation of Enpp1 1 0.30 0.71 0.04
24 INT247768 Fcer2a Positive_regulation of Enpp1 1 0.00 0.29 0.04
25 INT225801 Binding of Enpp1 and Npp 1 0.17 0.46 0.04
26 INT225800 Binding of Insr and Enpp1 1 0.05 0.67 0.04
27 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03
28 INT316598 Pth Regulation of Fgf23 1 0.10 0.28 0.03
29 INT225802 Binding of Enpp1 and Ppi-rs 1 0.04 1 0.03
30 INT301408 Positive_regulation of Binding of Enpp1 and Twist1 1 0.06 0.18 0.03
31 INT301406 Binding of Enpp1 and Twist1 1 0.04 0.18 0.03
32 INT256997 Binding of RLBP1 and Slc9a3r1 1 0.44 0 0
33 INT256979 Binding of Slc9a3r1 and Rlbp1 1 0.03 0 0
34 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0
35 INT266835 Pth Regulation of Slc34a3 1 0.19 0.07 0
36 INT256980 Binding of Slc9a3r1 and Rpe 1 0.08 0.13 0
37 INT301401 Binding of Enpp1 and Enpp2 1 0.23 0.54 0
38 INT225782 Tnfrsf11b Regulation of Enpp1 1 0.12 0.74 0
39 INT256992 Binding of Slc9a3r1 and Hspb6 1 0.09 0 0
40 INT256981 Binding of Dlg1 and Slc9a3r1 1 0.22 0 0
41 INT266839 Fgf23 Negative_regulation of Slc34a1 1 0.21 0.88 0
42 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0
43 INT256989 Binding of Ezr and Slc9a3r1 1 0.10 0 0
44 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0
45 INT266838 Fgf23 Regulation of Slc34a1 1 0.13 0.3 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cellular phosphate ion homeostasis. They are ordered first by their pain relevance and then by number of times they were reported in cellular phosphate ion homeostasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8
2 INT224530 Positive_regulation of Enpp1 12 0.70 7.03 5.82
3 INT68445 Gene_expression of ENPP1 10 0.70 10.8 3.3
4 INT207851 Regulation of Enpp1 5 0.45 4.42 2.96
5 INT107597 Binding of Enpp1 5 0.37 3.35 2.23
6 INT316778 Positive_regulation of Gene_expression of ENPP1 1 0.62 7.2 1.97
7 INT224529 Positive_regulation of Gene_expression of Enpp1 15 0.70 12.75 1.81
8 INT332460 Regulation of Binding of Enpp1 1 0.05 0.78 1.5
9 INT107599 Negative_regulation of Enpp1 8 0.51 6.02 1.24
10 INT118258 Positive_regulation of ENPP1 3 0.62 4.26 1.16
11 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04
12 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85
13 INT130797 Gene_expression of Fgf23 6 0.66 4.73 0.77
14 INT35098 Localization of Enpp1 4 0.75 0.81 0.67
15 INT130971 Binding of Slc9a3r1 2 0.39 0.32 0.59
16 INT130969 Positive_regulation of Binding of Slc9a3r1 1 0.09 0.26 0.43
17 INT225772 Regulation of Gene_expression of Enpp1 1 0.62 1.6 0.4
18 INT130972 Gene_expression of Slc9a3r1 2 0.63 0.36 0.37
19 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29
20 INT109156 Negative_regulation of ENPP1 2 0.34 1.34 0.29
21 INT130799 Localization of Fgf23 2 0.63 1.94 0.28
22 INT157409 Negative_regulation of Fgf23 3 0.50 3.21 0.27
23 INT130798 Positive_regulation of Gene_expression of Fgf23 2 0.59 1.12 0.2
24 INT175900 Regulation of ENPP1 1 0.00 1.96 0.16
25 INT252419 Phosphorylation of Enpp1 1 0.08 0.21 0.16
26 INT118372 Regulation of Fgf23 4 0.55 3.31 0.15
27 INT225771 Negative_regulation of Gene_expression of Enpp1 4 0.43 3.68 0.13
28 INT295974 Regulation of Fgf23 1 0.07 2.3 0.11
29 INT266826 Binding of Fgf23 1 0.32 1.26 0.07
30 INT189231 Binding of ENPP1 1 0.07 0.56 0.06
31 INT266828 Negative_regulation of Fgf23 3 0.42 5.63 0.04
32 INT316595 Transcription of Fgf23 1 0.61 0.44 0.04
33 INT316589 Negative_regulation of Transcription of Fgf23 1 0.50 0.44 0.04
34 INT295973 Gene_expression of Slc34a3 2 0.05 0.96 0.03
35 INT335007 Protein_catabolism of Fgf23 1 0.59 1.28 0.03
36 INT316588 Positive_regulation of Fgf23 1 0.43 0.29 0.03
37 INT319969 Positive_regulation of Negative_regulation of Enpp1 1 0.06 0.77 0.03
38 INT150308 Protein_catabolism of Fgf23 1 0.75 0.05 0
39 INT334982 Phosphorylation of Fgf23 1 0.73 1.21 0
40 INT335003 Negative_regulation of Localization of Fgf23 1 0.39 2.37 0
41 INT266831 Positive_regulation of Slc34a3 1 0.47 1.79 0
42 INT334997 Localization of Fgf23 1 0.72 3.56 0
43 INT256965 Positive_regulation of Slc9a3r1 1 0.38 0 0
44 INT266824 Regulation of Positive_regulation of Fgf23 1 0.27 1.22 0
45 INT266830 Regulation of Slc34a3 1 0.42 1.85 0
46 INT256950 Negative_regulation of Gene_expression of Slc9a3r1 1 0.35 0 0
47 INT334991 Positive_regulation of Positive_regulation of Fgf23 1 0.39 1.5 0
48 INT150307 Positive_regulation of Protein_catabolism of Fgf23 1 0.52 0.11 0
49 INT266825 Positive_regulation of Regulation of Fgf23 1 0.46 0.25 0
50 INT334993 Negative_regulation of Gene_expression of Fgf23 1 0.38 4.1 0
51 INT256962 Positive_regulation of Gene_expression of Slc9a3r1 1 0.38 0 0
52 INT256968 Localization of Slc9a3r1 1 0.57 0 0
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