GO:0030666

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Name endocytic vesicle membrane
Categary Component
Go Slim No
Go Link GO:0030666
Unique Molecular Interactions 109
Total Molecular Interactions 143
Total Single Events 1126
Pain Genes Associated 15

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for endocytic vesicle membrane. They are ordered first by their pain relevance and then by number of times they were reported for endocytic vesicle membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT278223 Binding of NOS3 and ACSM3 1 0.41 6.32 1.65
2 INT134764 Ghrl Regulation of Gene_expression of NOS3 1 0.02 2.66 1.4
3 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24
4 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 0.01 0.19 1.24
5 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
6 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
7 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17
8 INT322266 Binding of LIG4 and NOS3 1 0.02 2.35 0.82
9 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
10 INT312751 Phosphorylation of Gria1 Positive_regulation of GRIA1 1 0.18 0.22 0.55
11 INT278228 Binding of MBNL1 and NOS3 1 0.05 2.06 0.54
12 INT322809 Binding of GRIA3 and RS1 1 0.01 0.43 0.51
13 INT322811 Binding of GRIA1 and RS1 1 0.00 0.43 0.51
14 INT169083 Binding of GRIA3 and MOCOS 2 0.07 0.51 0.5
15 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
16 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
17 INT137834 Binding of CAMK2B and CTS 1 0.05 1.38 0.42
18 INT38269 Binding of TCN1 and CUBN 1 0.00 0.28 0.4
19 INT322810 SLC12A1 Regulation of Binding of GRIA1 1 0.00 0.39 0.36
20 INT278226 Binding of FOSB and NOS3 1 0.03 1.22 0.36
21 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
22 INT163762 MDM2 Positive_regulation of Gene_expression of BAX 1 0.27 0.86 0.3
23 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
24 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
25 INT118852 Positive_regulation of GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
26 INT118846 GNA14 Positive_regulation of CAMK2G 1 0.01 0.09 0.27
27 INT45196 Cubn Negative_regulation of Prl 1 0.05 0 0.27
28 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
29 INT246576 EEF1A2 Negative_regulation of Negative_regulation of NOSTRIN 1 0.04 0.63 0.24
30 INT171126 Lta Positive_regulation of NOSTRIN 1 0.01 0.76 0.24
31 INT171124 Spg7 Positive_regulation of NOSTRIN 1 0.01 0.76 0.24
32 INT325008 TNF Negative_regulation of Gene_expression of NOSTRIN 1 0.00 1.78 0.23
33 INT325007 TNF Negative_regulation of NOSTRIN 1 0.00 1.78 0.23
34 INT281901 Binding of KNG1 and NOS3 1 0.05 0.17 0.22
35 INT175908 Binding of NOS3 and ROS1 1 0.10 1.84 0.19
36 INT137417 MAPK7 Regulation of Gene_expression of NOS3 1 0.00 0.5 0.19
37 INT269333 Binding of BDKRB2 and NOS3 1 0.02 0 0.17
38 INT331768 Binding of Arg1 and NOSTRIN 1 0.01 0.6 0.17
39 INT261518 Binding of DLG4 and HTR4 1 0.01 0 0.16
40 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
41 INT261520 Binding of DLG4 and HTR2A 1 0.06 0 0.14
42 INT269332 Binding of NOS3 and TMPO 1 0.01 0 0.12
43 INT281905 Binding of AGTR2 and NOS3 1 0.08 0.37 0.1
44 INT184814 NOS3 Positive_regulation of Gene_expression of NOS1 1 0.09 0.54 0.1
45 INT281899 Binding of ANG and NOS3 1 0.12 0.37 0.1
46 INT252790 Binding of NOS1 and NOS3 1 0.03 0.37 0.1
47 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09
48 INT252803 Binding of NOS3 and ISYNA1 1 0.02 0.32 0.09
49 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
50 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
51 INT272365 Gene_expression of Adarb1 Positive_regulation of Gene_expression of GRIA1 1 0.00 0.26 0.09
52 INT193790 ITIH4 Regulation of Gene_expression of MDM2 1 0.06 0.45 0.07
53 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07
54 INT220537 HSPG2 Positive_regulation of NOSTRIN 1 0.04 0 0.05
55 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
56 INT231438 LEP Positive_regulation of Negative_regulation of NOS3 1 0.09 0.32 0.03
57 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
58 INT181618 NOS3 Positive_regulation of INS 1 0.02 0.59 0.03
59 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03
60 INT281908 VEGFA Positive_regulation of NOS3 1 0.14 0.14 0
61 INT183248 LPA Positive_regulation of NOS3 1 0.02 0 0
62 INT351167 CAV1 Negative_regulation of Ppp2r1a 1 0.08 1.5 0
63 INT314746 Akt1 Positive_regulation of Phosphorylation of MDM2 1 0.32 1.16 0
64 INT318081 Binding of RPL5 and UBC 1 0.02 0.52 0
65 INT288594 Regulation of Binding of CAV1 and Kcnma1 1 0.01 0 0
66 INT183895 CAV1 Regulation of Positive_regulation of Racgap1 1 0.01 0.37 0
67 INT297000 Binding of AP2A1 and AP1B1 1 0.00 0.21 0
68 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
69 INT133825 TNF Negative_regulation of NOS3 1 0.28 0.06 0
70 INT351166 Gtf3a Positive_regulation of Gene_expression of CAV1 1 0.01 0.79 0
71 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0
72 INT351156 VEGFA Positive_regulation of Gene_expression of CAV1 1 0.07 0.79 0
73 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0
74 INT306256 MDM2 Negative_regulation of Positive_regulation of TP53 1 0.23 0.44 0
75 INT318103 Binding of UBC and Hprt 1 0.10 0.52 0
76 INT288597 Binding of CAV1 and Kcnma1 1 0.01 0.17 0
77 INT288596 Positive_regulation of Binding of CAV1 and Kcnma1 1 0.01 0.1 0
78 INT309746 CALM3 Positive_regulation of CAMK2G 1 0.02 0 0
79 INT183857 CAV1 Positive_regulation of RHOC 1 0.46 0.21 0
80 INT165511 Binding of HSPG2 and NOSTRIN 1 0.02 0.07 0
81 INT183861 Binding of CAV1 and CDC42EP5 1 0.03 3.21 0
82 INT333450 ATM Positive_regulation of Negative_regulation of MDM2 1 0.18 0 0
83 INT183864 Gene_expression of CAV1 Negative_regulation of Positive_regulation of RHOC 1 0.39 0.95 0
84 INT351165 Binding of CAV1 and Nos3 1 0.09 1.46 0
85 INT313272 Binding of DLG4 and GRIN1 1 0.09 0.06 0
86 INT351157 TSC1 Positive_regulation of Gene_expression of CAV1 1 0.01 1.43 0
87 INT183860 Binding of RHOC and CAV1 1 0.34 0.4 0
88 INT183856 Negative_regulation of RHOC Positive_regulation of Gene_expression of CAV1 1 0.42 0.09 0
89 INT183868 CAV1 Positive_regulation of PAF1 1 0.54 0.41 0
90 INT133824 IL1B Negative_regulation of NOS3 1 0.48 0.06 0
91 INT208152 Binding of CDK4 and MDM2 1 0.01 1.11 0
92 INT294523 Binding of MDM2 and PDB1 1 0.40 0.1 0
93 INT351164 CAV1 Negative_regulation of Ppp1cc 1 0.11 1.5 0
94 INT333560 NOS3 Regulation of HCK 1 0.01 0.2 0
95 INT333458 ATM Positive_regulation of MDM2 1 0.25 0 0
96 INT204321 NOS3 Regulation of SIRT1 1 0.23 0.1 0
97 INT297003 Binding of AP1B1 and AP2B1 1 0.00 0.21 0
98 INT351158 CAV1 Regulation of SRC 1 0.01 0.68 0
99 INT294527 Binding of MDM2 and p53 1 0.40 0.1 0
100 INT175194 Binding of UBC and NUP62 1 0.01 0.05 0
101 INT183866 CAV1 Regulation of RHOC 1 0.25 0.2 0
102 INT183867 Binding of CAV1 and Positive_regulation of Positive_regulation of RHOC 1 0.46 0.1 0
103 INT294524 Binding of MDM2 and TNF 1 0.03 0.1 0
104 INT183852 CAV1 Regulation of Positive_regulation of RHOC 1 0.41 0.63 0
105 INT288558 Binding of CAV1 and KCNMA1 1 0.00 0 0
106 INT294522 Binding of IL2 and MDM2 1 0.40 0.2 0
107 INT351159 CAV1 Positive_regulation of AKT1 1 0.11 0.87 0
108 INT183854 Regulation of CAV1 Positive_regulation of RHOC 1 0.41 0.26 0
109 INT214922 Binding of MDM2 and TP53 1 0.08 1.55 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for endocytic vesicle membrane. They are ordered first by their pain relevance and then by number of times they were reported in endocytic vesicle membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT83201 Gene_expression of NOS3 93 0.78 47.16 12.48
2 INT48335 Negative_regulation of NOSTRIN 38 0.56 16.22 12.05
3 INT73959 Positive_regulation of NOSTRIN 49 0.61 31.1 11.27
4 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68
5 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
6 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
7 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92
8 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5
9 INT115074 Positive_regulation of GRIA1 10 0.67 2.66 4.48
10 INT48784 Gene_expression of GRIA1 12 0.78 3.25 4.11
11 INT48786 Phosphorylation of GRIA1 7 0.80 1.89 3.91
12 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
13 INT18822 Regulation of Cubn 4 0.27 0.17 3.74
14 INT70958 Binding of NOS3 19 0.37 11.84 3.29
15 INT92814 Negative_regulation of NOS3 25 0.51 20.67 3.07
16 INT91869 Transcription of NOS3 13 0.67 6.81 2.86
17 INT169088 Gene_expression of GRIA3 7 0.76 1.32 2.67
18 INT123978 Binding of GRIA1 3 0.41 3.5 2.62
19 INT110304 Negative_regulation of Gene_expression of NOSTRIN 6 0.55 2.22 2.27
20 INT96856 Localization of NOSTRIN 8 0.49 6.39 2.19
21 INT195191 Gene_expression of Cubn 2 0.06 0 2.17
22 INT82166 Regulation of NOS3 14 0.54 7.57 2.08
23 INT91594 Localization of NOS3 12 0.78 5.39 2.02
24 INT41633 Positive_regulation of Positive_regulation of Cubn 2 0.48 0.1 1.89
25 INT48787 Regulation of GRIA1 5 0.27 1.28 1.88
26 INT89639 Phosphorylation of CAMK2G 5 0.48 0.66 1.78
27 INT107923 Regulation of Gene_expression of NOS3 11 0.61 2.73 1.73
28 INT94892 Regulation of NOSTRIN 7 0.31 2.99 1.72
29 INT322821 Binding of GRIA3 1 0.47 2.06 1.67
30 INT65684 Gene_expression of MDM2 30 0.62 24.94 1.55
31 INT136251 Regulation of Positive_regulation of GRIA1 1 0.44 0.07 1.46
32 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41
33 INT12806 Positive_regulation of AP2M1 2 0.67 0.19 1.35
34 INT91863 Negative_regulation of Gene_expression of NOS3 13 0.51 9.43 1.34
35 INT62896 Binding of NOSTRIN 4 0.30 2.86 1.3
36 INT257952 Positive_regulation of CUBN 1 0.07 0.61 1.22
37 INT44498 Localization of Cubn 2 0.34 0.38 1.19
38 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
39 INT41333 Negative_regulation of Positive_regulation of Cubn 2 0.15 0.47 1.12
40 INT322822 Regulation of GRIA3 4 0.61 1.19 1.11
41 INT159477 Phosphorylation of NOS3 14 0.72 1.54 1.08
42 INT115075 Negative_regulation of Gene_expression of GRIA1 1 0.57 0 1.08
43 INT97383 Positive_regulation of Positive_regulation of NOSTRIN 2 0.08 1.53 1.05
44 INT107922 Positive_regulation of Gene_expression of NOS3 17 0.60 9.32 1.04
45 INT73960 Regulation of Gene_expression of NOSTRIN 3 0.54 1.41 0.97
46 INT207773 Negative_regulation of GRIA1 2 0.57 0.85 0.97
47 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
48 INT115077 Regulation of Gene_expression of GRIA1 3 0.45 0.44 0.88
49 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
50 INT44500 Regulation of Localization of Cubn 1 0.20 0 0.75
51 INT115076 Negative_regulation of Positive_regulation of GRIA1 1 0.41 0.26 0.72
52 INT257951 Localization of CUBN 1 0.07 0 0.71
53 INT152562 Regulation of Transcription of NOS3 1 0.23 0.34 0.71
54 INT322816 Transcription of GRIA3 2 0.71 0.75 0.7
55 INT59696 Gene_expression of AP2M1 1 0.65 0.23 0.7
56 INT257948 Binding of CUBN 1 0.05 0 0.7
57 INT153667 Localization of CAV1 15 0.76 11.92 0.68
58 INT235561 Localization of GRIA1 2 0.06 0.37 0.68
59 INT322819 Regulation of Binding of GRIA3 1 0.61 1.07 0.68
60 INT69349 Transcription of NOSTRIN 2 0.50 0.49 0.66
61 INT13894 Regulation of Negative_regulation of Cubn 1 0.13 0.09 0.63
62 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
63 INT124269 Binding of Cubn 1 0.28 0.2 0.59
64 INT159476 Positive_regulation of Phosphorylation of NOS3 6 0.44 1.43 0.58
65 INT174274 Positive_regulation of Localization of NOSTRIN 2 0.09 2.35 0.58
66 INT230974 Positive_regulation of Gene_expression of GRIA3 2 0.49 0 0.57
67 INT94564 Positive_regulation of Negative_regulation of NOSTRIN 1 0.38 0.35 0.57
68 INT200956 Negative_regulation of CAMK2B 1 0.37 0.93 0.56
69 INT243864 Gene_expression of DLG4 5 0.34 0.22 0.54
70 INT128569 Regulation of Positive_regulation of Cubn 1 0.09 0 0.49
71 INT91864 Negative_regulation of Transcription of NOS3 4 0.54 1.41 0.48
72 INT113532 Binding of AP2M1 1 0.47 0.19 0.47
73 INT149425 Transcription of GRIA1 3 0.52 0.66 0.46
74 INT235562 Positive_regulation of Localization of GRIA1 1 0.01 0.37 0.46
75 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
76 INT137835 Binding of CAMK2B 1 0.08 1.38 0.42
77 INT352667 Positive_regulation of Transcription of GRIA3 1 0.08 0.39 0.42
78 INT159479 Positive_regulation of Binding of NOS3 2 0.50 0.63 0.41
79 INT352661 Positive_regulation of GRIA3 1 0.12 0.33 0.41
80 INT97384 Negative_regulation of Positive_regulation of NOSTRIN 3 0.12 0.93 0.4
81 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
82 INT169090 Regulation of Gene_expression of GRIA3 2 0.61 0.46 0.32
83 INT115164 Positive_regulation of Phosphorylation of GRIA1 1 0.49 0.66 0.32
84 INT322820 Localization of GRIA3 1 0.74 0.31 0.31
85 INT5397 Negative_regulation of AP2B1 1 0.08 0.4 0.28
86 INT89637 Negative_regulation of CAMK2G 1 0.26 0 0.28
87 INT118866 Positive_regulation of CAMK2G 1 0.16 0.09 0.27
88 INT233915 Protein_catabolism of NOSTRIN 1 0.02 1.6 0.24
89 INT246583 Negative_regulation of Negative_regulation of NOSTRIN 1 0.04 0.63 0.24
90 INT167250 Regulation of Gene_expression of MDM2 1 0.06 0.86 0.21
91 INT88744 Positive_regulation of Gene_expression of MDM2 9 0.43 7.82 0.2
92 INT322824 Regulation of Regulation of GRIA3 1 0.44 0.42 0.2
93 INT269409 Regulation of Phosphorylation of NOS3 1 0.18 0 0.2
94 INT92815 Positive_regulation of Negative_regulation of NOS3 1 0.12 1.03 0.2
95 INT243875 Positive_regulation of Gene_expression of DLG4 1 0.30 0.22 0.19
96 INT269403 Regulation of Positive_regulation of NOS3 1 0.18 0 0.17
97 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
98 INT126733 Regulation of MDM2 2 0.36 0.73 0.16
99 INT113346 Binding of MDM2 10 0.35 5.73 0.15
100 INT243883 Negative_regulation of DLG4 1 0.19 0.07 0.15
101 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
102 INT200987 Transcription of CAMK2B 2 0.44 0.2 0.14
103 INT200978 Regulation of Transcription of CAMK2B 1 0.29 0.15 0.14
104 INT94893 Regulation of Positive_regulation of NOSTRIN 1 0.01 0.51 0.13
105 INT269395 Regulation of Binding of NOS3 2 0.39 1.84 0.12
106 INT149424 Positive_regulation of Gene_expression of GRIA1 2 0.49 0.17 0.11
107 INT186558 Negative_regulation of Positive_regulation of NOS3 2 0.37 0.26 0.1
108 INT201016 Positive_regulation of AP2B1 2 0.36 1.01 0.09
109 INT192238 Positive_regulation of Localization of NOS3 2 0.21 0.76 0.09
110 INT156437 Binding of DLG4 2 0.35 0.29 0.07
111 INT318095 Gene_expression of UBC 1 0.16 1.24 0.04
112 INT287282 Regulation of Binding of MDM2 1 0.04 0.63 0.04
113 INT314252 Transcription of CAV1 1 0.50 0.07 0.04
114 INT183878 Negative_regulation of Positive_regulation of CAV1 1 0.41 0.16 0.03
115 INT126734 Positive_regulation of MDM2 8 0.49 5.56 0
116 INT183883 Binding of CAV1 8 0.46 3.89 0
117 INT156919 Phosphorylation of NOSTRIN 2 0.30 0.18 0
118 INT260276 Negative_regulation of MDM2 2 0.42 0.62 0
119 INT276357 Protein_catabolism of MDM2 2 0.32 1.18 0
120 INT156921 Positive_regulation of Phosphorylation of NOSTRIN 2 0.26 0.18 0
121 INT244607 Gene_expression of CAMK2B 2 0.23 0.23 0
122 INT276370 Phosphorylation of MDM2 2 0.50 1.99 0
123 INT297043 Regulation of AP2B1 1 0.19 1.22 0
124 INT294536 Localization of MDM2 1 0.73 0.09 0
125 INT354644 Gene_expression of CUBN 1 0.65 0.32 0
126 INT121497 Transcription of MDM2 1 0.54 0.12 0
127 INT336827 Regulation of Regulation of NOS3 1 0.23 0.51 0
128 INT183890 Regulation of Negative_regulation of CAV1 1 0.43 0.38 0
129 INT348166 Localization of DLG4 1 0.11 1.13 0
130 INT175213 Negative_regulation of Binding of UBC 1 0.02 0.13 0
131 INT235473 Negative_regulation of Gene_expression of MDM2 1 0.18 0.99 0
132 INT156902 Positive_regulation of UBC 1 0.49 0 0
133 INT288581 Negative_regulation of Binding of CAV1 1 0.03 0 0
134 INT48334 Regulation of Negative_regulation of NOSTRIN 1 0.43 0.08 0
135 INT174535 Negative_regulation of Negative_regulation of NOS3 1 0.11 0.32 0
136 INT297036 Regulation of Gene_expression of AP2B1 1 0.32 0.54 0
137 INT276343 Regulation of Phosphorylation of MDM2 1 0.14 0.85 0
138 INT276359 Positive_regulation of Protein_catabolism of MDM2 1 0.15 1.79 0
139 INT276366 Positive_regulation of Phosphorylation of MDM2 1 0.15 0.85 0
140 INT288580 Regulation of Binding of CAV1 1 0.03 0 0
141 INT149423 Positive_regulation of Transcription of GRIA1 1 0.01 0.06 0
142 INT113347 Negative_regulation of Binding of MDM2 1 0.25 0.13 0
143 INT175222 Binding of UBC 1 0.02 0.54 0
144 INT276365 Negative_regulation of Protein_catabolism of MDM2 1 0.14 0.86 0
145 INT297032 Gene_expression of AP2B1 1 0.48 0.54 0
146 INT140156 Positive_regulation of Transcription of NOS3 1 0.31 0 0
147 INT354089 Positive_regulation of Transcription of CAMK2B 1 0.09 0.05 0
148 INT159478 Negative_regulation of Phosphorylation of NOS3 1 0.51 0 0
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