GO:0030675

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Name Rac GTPase activator activity
Categary Function
Go Slim No
Go Link GO:0030675
Unique Molecular Interactions 43
Total Molecular Interactions 51
Total Single Events 334
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for Rac GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported for Rac GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT125234 Positive_regulation of Binding of BCR and CD40LG 1 0.31 0.76 0.86
2 INT125233 Binding of BCR and CD40LG 1 0.23 0.75 0.85
3 INT316884 Positive_regulation of Binding of Cr2 and Bcr 1 0.06 0.86 0.31
4 INT316881 Positive_regulation of Binding of Cd19 and Bcr 1 0.08 0.86 0.31
5 INT316885 Binding of Cr2 and Bcr 1 0.06 0.85 0.3
6 INT316888 Binding of Cd19 and Bcr 1 0.08 0.85 0.3
7 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29
8 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29
9 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
10 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
11 INT47351 Binding of Ralbp1 and Ccl4 1 0.11 0.17 0.14
12 INT47352 Positive_regulation of Binding of Ralbp1 and Ccl4 1 0.14 0.17 0.14
13 INT293697 Dock2 Positive_regulation of Akt1 1 0.14 0.08 0.13
14 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09
15 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08
16 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08
17 INT325261 Ralbp1 Positive_regulation of Gene_expression of Il33 1 0.01 0 0.05
18 INT277765 Binding of BCR and Abl1 1 0.18 1.55 0.03
19 INT232900 Binding of ABR and Krt8 1 0.03 0.49 0.03
20 INT316500 INO80B Positive_regulation of RALBP1 1 0.00 0.31 0
21 INT72209 BCR Positive_regulation of Mapk13 1 0.00 0 0
22 INT218509 Binding of BCR and Cfb 1 0.00 0.18 0
23 INT232899 Krt18 Negative_regulation of Binding of ABR 1 0.05 0.68 0
24 INT218514 BCR Negative_regulation of Binding of Cfb 1 0.00 0.18 0
25 INT232893 Binding of ABR and Nup62 1 0.03 0.13 0
26 INT232895 Krt18 Positive_regulation of Gene_expression of ABR 1 0.46 0.09 0
27 INT286422 Binding of Cdc42ep5 and Dock4 1 0.01 0.84 0
28 INT194926 Binding of CD40LG and Positive_regulation of BCR 1 0.04 0.39 0
29 INT277864 Binding of ERBB2 and Ralbp1 1 0.28 0.57 0
30 INT232896 Krt8 Negative_regulation of Binding of ABR 1 0.04 0.68 0
31 INT232384 Binding of BCR and C6orf25 1 0.00 0.91 0
32 INT347225 Hck Regulation of Positive_regulation of Bcr 1 0.15 0.07 0
33 INT229629 Binding of BCR and PAEP 1 0.04 0.37 0
34 INT313687 Binding of BCR and IFIH1 1 0.09 0.23 0
35 INT232894 Binding of ABR and Rab27a 1 0.08 0.3 0
36 INT347224 Lyn Regulation of Positive_regulation of Bcr 1 0.14 0.07 0
37 INT273197 Binding of BCR and COPD 1 0.03 0.4 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for Rac GTPase activator activity. They are ordered first by their pain relevance and then by number of times they were reported in Rac GTPase activator activity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT59790 Binding of BCR 16 0.36 15.34 1.75
2 INT235954 Gene_expression of Bcr 1 0.13 6.77 1.47
3 INT113659 Gene_expression of ABR 19 0.65 8.49 1.45
4 INT42391 Positive_regulation of BCR 7 0.49 4.93 1.44
5 INT11203 Gene_expression of BCR 30 0.75 33.49 1.22
6 INT17554 Regulation of ABR 6 0.54 2.21 0.98
7 INT42390 Regulation of Positive_regulation of BCR 1 0.00 0 0.87
8 INT110208 Binding of ABR 2 0.35 10.49 0.81
9 INT115757 Negative_regulation of ABR 3 0.57 0.53 0.8
10 INT273550 Positive_regulation of Bcr 14 0.68 6.71 0.49
11 INT199553 Gene_expression of Bcr 25 0.76 13.83 0.48
12 INT232886 Regulation of Gene_expression of ABR 3 0.06 1.42 0.45
13 INT273555 Negative_regulation of Bcr 17 0.57 9.65 0.44
14 INT193674 Binding of Bcr 10 0.47 4.3 0.36
15 INT235948 Regulation of Gene_expression of Bcr 1 0.08 1.58 0.36
16 INT199557 Positive_regulation of Gene_expression of Bcr 6 0.68 4.21 0.3
17 INT129166 Positive_regulation of Bcr 2 0.28 1.18 0.29
18 INT105135 Positive_regulation of Ralbp1 1 0.60 1.49 0.26
19 INT105134 Regulation of Ralbp1 1 0.23 1.5 0.26
20 INT192748 Localization of BCR 4 0.68 2.4 0.18
21 INT347214 Positive_regulation of Negative_regulation of Bcr 1 0.38 1.43 0.17
22 INT223459 Gene_expression of Dock4 2 0.71 1.5 0.16
23 INT223465 Regulation of Dock4 1 0.08 0.13 0.16
24 INT223463 Regulation of Gene_expression of Dock4 1 0.31 0.13 0.16
25 INT316515 Positive_regulation of RALBP1 28 0.25 10.37 0.14
26 INT129165 Positive_regulation of Binding of Bcr 1 0.00 0.59 0.14
27 INT129167 Binding of Bcr 1 0.00 0.59 0.14
28 INT232877 Negative_regulation of Binding of ABR 1 0.06 1.88 0.14
29 INT188260 Gene_expression of Ralbp1 1 0.02 0.53 0.14
30 INT47350 Binding of Ralbp1 1 0.10 0.17 0.14
31 INT232880 Phosphorylation of ABR 1 0.79 0.76 0.13
32 INT232875 Negative_regulation of Phosphorylation of ABR 1 0.41 0.76 0.13
33 INT320145 Negative_regulation of Phosphorylation of Bcr 2 0.35 0.23 0.11
34 INT320147 Phosphorylation of Bcr 2 0.67 0.64 0.11
35 INT316511 Gene_expression of RALBP1 5 0.28 5.24 0.1
36 INT25530 Positive_regulation of ABR 3 0.33 0.34 0.1
37 INT249113 Localization of Bcr 1 0.57 0.08 0.1
38 INT105132 Localization of Ralbp1 2 0.60 0.52 0.09
39 INT328094 Positive_regulation of Gene_expression of ABR 1 0.33 0 0.09
40 INT105133 Positive_regulation of Localization of Ralbp1 1 0.40 0.47 0.09
41 INT347217 Negative_regulation of Gene_expression of Bcr 1 0.35 0.17 0.08
42 INT232885 Positive_regulation of Binding of ABR 1 0.07 0.5 0.07
43 INT320146 Regulation of Gene_expression of Bcr 1 0.37 0.07 0.04
44 INT249116 Regulation of Bcr 1 0.24 0.33 0.04
45 INT326159 Positive_regulation of Gene_expression of RALBP1 1 0.25 1.58 0.03
46 INT136181 Negative_regulation of BCR 5 0.42 2.94 0
47 INT201927 Regulation of BCR 2 0.26 1.94 0
48 INT320148 Negative_regulation of Negative_regulation of Bcr 1 0.35 0.2 0
49 INT273551 Positive_regulation of Binding of Bcr 1 0.49 1.03 0
50 INT273557 Transcription of Bcr 1 0.70 0.3 0
51 INT316514 Regulation of Positive_regulation of RALBP1 1 0.07 0.38 0
52 INT201926 Phosphorylation of BCR 1 0.36 0.5 0
53 INT286398 Positive_regulation of Transcription of Dock4 1 0.46 0 0
54 INT218478 Transcription of BCR 1 0.01 0.32 0
55 INT232881 Regulation of Binding of ABR 1 0.07 1.43 0
56 INT232878 Protein_catabolism of ABR 1 0.96 0.09 0
57 INT273544 Negative_regulation of Transcription of Bcr 1 0.42 0.3 0
58 INT316512 Negative_regulation of Gene_expression of RALBP1 1 0.07 0.23 0
59 INT273549 Negative_regulation of Binding of Bcr 1 0.42 0.24 0
60 INT232884 Localization of ABR 1 0.10 1.05 0
61 INT286408 Transcription of Dock4 1 0.66 0 0
62 INT232882 Transcription of ABR 1 0.09 0.61 0
63 INT316509 Positive_regulation of Positive_regulation of RALBP1 1 0.08 0.65 0
64 INT259507 Regulation of Bcr 1 0.26 0.38 0
65 INT232876 Positive_regulation of Localization of ABR 1 0.07 0.24 0
66 INT232874 Negative_regulation of Localization of ABR 1 0.06 0.24 0
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