GO:0030819

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Name positive regulation of cAMP biosynthetic process
Categary Process
Go Slim No
Go Link GO:0030819
Unique Molecular Interactions 2043
Total Molecular Interactions 3436
Total Single Events 32350
Pain Genes Associated 76

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cAMP biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cAMP biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69872 Binding of MC1R and POMC 52 0.54 8.87 18.3
2 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2
3 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
4 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
5 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21
6 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
7 INT140015 Avp Positive_regulation of Localization of Penk 3 0.63 3.48 6.63
8 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49
9 INT338167 Binding of CDKN2A and MC1R 1 0.42 6.14 5.76
10 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
11 INT15842 Crh Positive_regulation of Localization of Pomc 15 0.73 5 5.05
12 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
13 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
14 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
15 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8
16 INT211710 Binding of Mc1r and a 7 0.44 0.37 4.78
17 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71
18 INT29206 Crh Regulation of Localization of POMC 4 0.64 0.96 4.68
19 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
20 INT38217 Penk Regulation of Localization of Avp 2 0.38 0.56 4.45
21 INT7022 Drd1a Positive_regulation of Npr1 6 0.05 0.26 4.32
22 INT113223 POMC Regulation of MC1R 6 0.68 0.39 4.24
23 INT161109 Avp Positive_regulation of Chkb 1 0.12 0.18 4.19
24 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
25 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08
26 INT11248 Gh Positive_regulation of Ghrh 2 0.26 0.09 4.04
27 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
28 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
29 INT113080 Drd1a Positive_regulation of Phosphorylation of Creb1 2 0.27 0.43 3.88
30 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
31 INT104977 MITF Regulation of Gene_expression of MC1R 1 0.69 0.91 3.71
32 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64
33 INT140011 Avp Positive_regulation of Dbi 2 0.07 0.93 3.61
34 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
35 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
36 INT152035 Binding of HLA-A and MRAP 2 0.31 6.95 3.4
37 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
38 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
39 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2
40 INT18793 Crh Regulation of Localization of Penk 1 0.59 0 3.2
41 INT34294 Penk Positive_regulation of Localization of Crh 1 0.16 0.43 3.19
42 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
43 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
44 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
45 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
46 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
47 INT140014 Avp Negative_regulation of Chkb 1 0.04 1.58 2.86
48 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
49 INT107723 POMC Positive_regulation of MC1R 7 0.68 0.71 2.82
50 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
51 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78
52 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
53 INT62450 Il2 Positive_regulation of Localization of Crh 1 0.43 0.59 2.64
54 INT7888 Oprl1 Regulation of Localization of Avp 4 0.49 0.25 2.63
55 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
56 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58
57 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
58 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
59 INT327940 Crh Positive_regulation of Gene_expression of F2rl1 1 0.44 5.57 2.5
60 INT20411 Ghrh Positive_regulation of Gh1 6 0.56 0.62 2.47
61 INT21520 Crh Regulation of Pomc 3 0.22 0.4 2.45
62 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
63 INT29716 Crh Negative_regulation of Localization of Gnrh1 5 0.44 0 2.35
64 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
65 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
66 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
67 INT7367 Ghrh Regulation of Localization of Gh1 5 0.49 1.55 2.25
68 INT18197 Ghrh Positive_regulation of Localization of Ggh 4 0.46 0 2.23
69 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
70 INT9180 Ghrh Regulation of Localization of Gh 3 0.24 0.25 2.18
71 INT49242 Binding of Mc1r and Pomc 10 0.38 3.79 2.15
72 INT66803 Oxt Regulation of Avp 7 0.16 0.19 2.15
73 INT18791 Crh Regulation of Penk 2 0.49 0 2.15
74 INT140019 Avp Positive_regulation of Localization of Kitl 1 0.00 1 2.13
75 INT120319 Ghrh Regulation of Ngf 1 0.25 1.89 2.11
76 INT356313 Crh Positive_regulation of Localization of Helt 1 0.02 0 2.11
77 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
78 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
79 INT331105 Vmn1r71 Negative_regulation of Mc1r 1 0.04 0.64 2.07
80 INT30954 Crh Negative_regulation of LH 5 0.46 1.4 2.06
81 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
82 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
83 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
84 INT35502 Ghrh Positive_regulation of Localization of Gnrhr 7 0.57 0.18 2
85 INT138960 Dbi Positive_regulation of Avp 1 0.02 1.53 2
86 INT138958 Dbi Positive_regulation of Positive_regulation of Avp 1 0.02 1.53 2
87 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
88 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99
89 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
90 INT45423 Avp Positive_regulation of Localization of Prl 4 0.67 1.37 1.98
91 INT163266 Crh Negative_regulation of Tyr 1 0.01 0.45 1.98
92 INT110525 Binding of MC1R and OCA2 1 0.41 1.08 1.97
93 INT165284 Positive_regulation of Nts Positive_regulation of Crh 1 0.40 1.86 1.93
94 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
95 INT149470 Oxt Regulation of Gene_expression of Avp 1 0.46 1.2 1.92
96 INT165285 Nts Positive_regulation of Crh 1 0.40 1.84 1.91
97 INT149469 Oxt Regulation of Gene_expression of Crh 1 0.45 1.2 1.91
98 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
99 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
100 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
101 INT40239 Penk Regulation of Avp 1 0.07 0 1.84
102 INT16891 GHRH Regulation of GH1 5 0.37 1.94 1.82
103 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
104 INT7023 Negative_regulation of Drd1a Positive_regulation of Npr1 2 0.05 0.1 1.81
105 INT117269 Binding of Avp and Prl 1 0.25 0.47 1.8
106 INT29715 Crh Negative_regulation of Localization of LH 5 0.43 0 1.78
107 INT276863 Gpr65 Regulation of Trpv1 1 0.25 1.78 1.75
108 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
109 INT68709 Positive_regulation of Crh Regulation of Npr1 1 0.03 0 1.71
110 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
111 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
112 INT68710 Crh Regulation of Npr1 1 0.03 0 1.7
113 INT341372 CRX Positive_regulation of Gene_expression of Crh 1 0.04 1.81 1.7
114 INT70148 Drd1a Positive_regulation of Localization of Acot1 1 0.14 0 1.7
115 INT10202 Agt Positive_regulation of Avp 3 0.70 0 1.69
116 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
117 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
118 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
119 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
120 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
121 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
122 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
123 INT140009 Avp Positive_regulation of Gene_expression of Penk 1 0.40 0.77 1.64
124 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
125 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62
126 INT140023 Avp Positive_regulation of Gene_expression of Kitl 1 0.00 0.76 1.62
127 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
128 INT94270 Pomc Regulation of Transcription of Crh 1 0.17 0.67 1.6
129 INT151020 Binding of Pdyn and Crh 1 0.14 0.42 1.59
130 INT356327 Crh Positive_regulation of Localization of Gabrg1 1 0.17 0 1.58
131 INT94271 Pomc Regulation of Avp 1 0.20 0.67 1.57
132 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
133 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
134 INT209087 Crh Positive_regulation of Ceacam3 1 0.24 1.45 1.54
135 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
136 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
137 INT145072 ASIP Negative_regulation of MC1R 1 0.29 0 1.52
138 INT140013 Avp Positive_regulation of Gene_expression of Dbi 1 0.07 0.85 1.52
139 INT140016 Avp Positive_regulation of Gene_expression of Pdyn 1 0.21 0.85 1.52
140 INT140017 Avp Positive_regulation of Gene_expression of Pomc 1 0.38 0.85 1.52
141 INT140008 Avp Positive_regulation of Pomc 1 0.38 0.84 1.51
142 INT166360 Negative_regulation of Crhr1 Negative_regulation of Positive_regulation of Pomc 1 0.02 0.36 1.5
143 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
144 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47
145 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
146 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
147 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
148 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
149 INT45307 ENG Positive_regulation of Localization of Avp 1 0.00 0 1.45
150 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
151 INT140012 Avp Negative_regulation of Dbi 1 0.06 0.8 1.44
152 INT5534 Binding of Oxt and Avp 7 0.04 0.6 1.43
153 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
154 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
155 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41
156 INT34834 Ghrh Positive_regulation of Gene_expression of Gh1 2 0.65 0 1.4
157 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
158 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
159 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4
160 INT142490 Avp Regulation of Oxt 1 0.09 0.74 1.4
161 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
162 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
163 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38
164 INT140021 Avp Positive_regulation of Pag1 1 0.03 0.85 1.38
165 INT140018 Avp Positive_regulation of Gene_expression of Pag1 1 0.04 0.85 1.38
166 INT140020 Avp Positive_regulation of Localization of Pag1 1 0.03 0.85 1.38
167 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
168 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
169 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
170 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
171 INT290542 Crh Positive_regulation of Insr 1 0.02 0.36 1.36
172 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
173 INT261463 Binding of Drd1a and Sftpd 1 0.12 0.13 1.35
174 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
175 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
176 INT356317 Crhr1 Regulation of Gene_expression of Cea 1 0.18 0.65 1.33
177 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
178 INT356326 Crhr1 Regulation of Gene_expression of Helt 1 0.01 0.65 1.32
179 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
180 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
181 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
182 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
183 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
184 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
185 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
186 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
187 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
188 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
189 INT276282 Binding of Atrn and Mc1r 1 0.32 0.41 1.29
190 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
191 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
192 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
193 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
194 INT71109 Binding of INSRR and MC1R 1 0.01 0 1.27
195 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
196 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
197 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
198 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
199 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
200 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cAMP biosynthetic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cAMP biosynthetic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT477 Localization of Avp 813 0.81 131.58 300.4
8 INT1562 Localization of Crh 499 0.81 126.74 236.68
9 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
10 INT626 Localization of CALCA 289 0.81 125.39 221.15
11 INT438 Gene_expression of Crh 376 0.78 159.11 169.17
12 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
13 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69
14 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
15 INT1273 Gene_expression of Avp 356 0.78 90.56 138.7
16 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
17 INT2541 Binding of Calca 200 0.48 67.14 134.62
18 INT5497 Positive_regulation of Crh 299 0.70 125.54 131.14
19 INT5008 Localization of Calca 204 0.81 80.35 125.16
20 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
21 INT4207 Regulation of Avp 267 0.62 63.72 115.33
22 INT1898 Regulation of Crh 220 0.62 61.33 102.64
23 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2
24 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
25 INT56130 Gene_expression of MC1R 259 0.78 62.7 97.55
26 INT214 Localization of AVP 370 0.81 208.51 91.09
27 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
28 INT4358 Positive_regulation of Localization of Avp 195 0.70 30.79 77.58
29 INT7886 Regulation of Localization of Avp 146 0.62 14.53 72.99
30 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72
31 INT5095 Localization of Ghrh 185 0.81 28.09 62.08
32 INT6761 Binding of CALCA 100 0.48 26.71 62.05
33 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
34 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28
35 INT21737 Binding of MC1R 129 0.48 45.45 56.54
36 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
37 INT5509 Positive_regulation of Localization of Crh 91 0.70 30.65 53.92
38 INT4891 Transcription of Calca 81 0.72 35.27 53.75
39 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
40 INT249 Localization of GHRH 215 0.80 78.02 51.87
41 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
42 INT5858 Positive_regulation of Drd1a 66 0.69 4.51 51.73
43 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
44 INT62426 Gene_expression of Mc1r 127 0.78 42.99 48.01
45 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41
46 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
47 INT5502 Positive_regulation of Gene_expression of Crh 69 0.70 43.06 42.23
48 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
49 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52
50 INT685 Regulation of AVP 124 0.62 34.9 39.91
51 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23
52 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
53 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
54 INT1473 Localization of Gcg 95 0.80 17.35 30.31
55 INT5507 Regulation of Localization of Crh 57 0.61 8.43 30.26
56 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21
57 INT894 Binding of Avp 84 0.48 29.16 29.63
58 INT5514 Negative_regulation of Localization of Crh 64 0.58 8.12 29.29
59 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
60 INT16879 Binding of Crh 72 0.48 21.65 28.43
61 INT22499 Regulation of Calca 42 0.62 17.32 28.02
62 INT233457 Gene_expression of Gpr65 56 0.68 26.57 27.94
63 INT21379 Transcription of Crh 65 0.72 15.64 27.92
64 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54
65 INT62169 Positive_regulation of MC1R 72 0.69 14.56 27.52
66 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26
67 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9
68 INT7584 Gene_expression of Crh 112 0.78 39.15 25.33
69 INT17625 Localization of GCG 210 0.80 55.69 24.97
70 INT13334 Gene_expression of Drd1a 43 0.62 7.73 24.43
71 INT682 Negative_regulation of AVP 97 0.59 50.67 23.91
72 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88
73 INT13838 Positive_regulation of Drd1a 48 0.70 9.83 23.42
74 INT250 Regulation of GHRH 65 0.61 17.46 23.19
75 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
76 INT5503 Negative_regulation of Gene_expression of Crh 38 0.59 16.82 21.34
77 INT6127 Regulation of Localization of AVP 60 0.62 15.12 20.84
78 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74
79 INT440 Regulation of Gene_expression of Crh 44 0.62 17.71 20.73
80 INT7470 Positive_regulation of Gene_expression of Avp 37 0.70 19.55 19.96
81 INT5499 Transcription of Avp 52 0.72 7.98 19.87
82 INT8075 Localization of Crh 64 0.81 25.41 19.45
83 INT64442 Regulation of Mc4r 6 0.62 5.22 19.09
84 INT7364 Regulation of Ghrh 49 0.58 8.05 19.05
85 INT7680 Regulation of Drd1a 27 0.45 4.52 18.86
86 INT636 Binding of MRAP 54 0.48 40.36 18.77
87 INT9179 Positive_regulation of Localization of Ghrh 42 0.70 7.05 18.1
88 INT51779 Gene_expression of Drd1a 46 0.66 11.18 17.51
89 INT22068 Binding of CALCRL 53 0.41 6.14 17.32
90 INT7020 Negative_regulation of Drd1a 25 0.57 1.84 17.1
91 INT125947 Gene_expression of Adora2b 57 0.75 23.69 17
92 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
93 INT276855 Positive_regulation of Gene_expression of Gpr65 1 0.61 17.04 16.96
94 INT84712 Regulation of MC1R 36 0.62 9.34 16.91
95 INT213 Negative_regulation of Localization of AVP 46 0.59 19.78 16.79
96 INT54077 Gene_expression of Adcyap1 62 0.78 23.17 16.75
97 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64
98 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51
99 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
100 INT9751 Localization of Crhr1 26 0.78 10.47 15.69
101 INT5859 Positive_regulation of Positive_regulation of Drd1a 20 0.55 2.05 15.61
102 INT216751 Gene_expression of ADORA2B 36 0.60 3.42 15.6
103 INT42810 Gene_expression of CALCRL 53 0.77 10.87 15.42
104 INT64447 Transcription of Mc4r 14 0.61 6.08 15.29
105 INT21177 Positive_regulation of Crh 39 0.70 17.5 15.28
106 INT170 Negative_regulation of Adrb1 52 0.55 13.46 14.78
107 INT58896 Localization of Adcyap1 35 0.81 4.57 14.77
108 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45
109 INT95 Positive_regulation of Adrb1 34 0.62 11.95 14.41
110 INT48259 Positive_regulation of Adcyap1 33 0.67 10.94 14.39
111 INT15042 Gene_expression of Adora2a 37 0.77 3.77 14.24
112 INT1873 Gene_expression of MRAP 51 0.76 31.75 13.92
113 INT194850 Positive_regulation of Adora2b 43 0.61 20.57 13.89
114 INT108063 Gene_expression of Adora2a 29 0.78 13.11 13.78
115 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44
116 INT146053 Positive_regulation of Gpr65 2 0.61 12.11 13.38
117 INT6575 Positive_regulation of Localization of Gcg 33 0.69 3.48 13.31
118 INT65965 Gene_expression of Adcyap1 52 0.78 22.53 13.14
119 INT7585 Regulation of Crh 24 0.58 9.88 12.97
120 INT97448 Negative_regulation of Mc1r 20 0.58 7.37 12.91
121 INT64445 Gene_expression of Mc4r 17 0.78 5.06 12.91
122 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
123 INT50227 Positive_regulation of Adora2a 32 0.50 5.17 12.75
124 INT26217 Binding of Calca 22 0.48 5.22 12.57
125 INT63104 Negative_regulation of CALCRL 29 0.37 13.62 12.42
126 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
127 INT11141 Negative_regulation of Gene_expression of Avp 23 0.59 3.85 12.19
128 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
129 INT65304 Positive_regulation of Gene_expression of MC1R 34 0.70 11.32 12.09
130 INT71030 Binding of Mc1r 39 0.48 10.27 12.02
131 INT89181 Gene_expression of Mc3r 33 0.77 22.48 11.85
132 INT7682 Binding of Drd1a 22 0.48 1.8 11.83
133 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
134 INT2586 Positive_regulation of Gcg 35 0.70 9.25 11.75
135 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7
136 INT13743 Regulation of Gene_expression of Avp 30 0.62 6.9 11.66
137 INT72784 Positive_regulation of Adora2a 26 0.70 16.52 11.47
138 INT254 Regulation of Localization of GHRH 30 0.60 5.17 11.46
139 INT5464 Regulation of CALCRL 24 0.16 4.2 11.19
140 INT104039 Positive_regulation of Crhr1 15 0.70 8.34 10.99
141 INT102448 Gene_expression of RAMP1 23 0.75 4.62 10.9
142 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
143 INT85017 Positive_regulation of Mc4r 13 0.67 7.56 10.86
144 INT36453 Binding of ABCA1 48 0.45 19.9 10.84
145 INT15262 Negative_regulation of Positive_regulation of Avp 22 0.58 3.28 10.81
146 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
147 INT89184 Gene_expression of Mc4r 55 0.77 23.85 10.65
148 INT19010 Negative_regulation of Localization of Ghrh 27 0.57 4.85 10.5
149 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34
150 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
151 INT637 Positive_regulation of MRAP 23 0.67 21.13 9.97
152 INT8740 Localization of Gcg 65 0.78 19 9.81
153 INT5465 Positive_regulation of CALCRL 25 0.49 7.24 9.8
154 INT59 Regulation of Adrb1 25 0.42 8.32 9.78
155 INT4494 Regulation of GCG 41 0.45 18.38 9.68
156 INT62919 Regulation of Gnas 22 0.43 5.61 9.55
157 INT26492 Negative_regulation of Localization of GCG 73 0.58 22.2 9.48
158 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27
159 INT64451 Negative_regulation of MC1R 21 0.59 4.94 9.22
160 INT106199 Positive_regulation of Adcyap1 32 0.68 13.68 9.14
161 INT30247 Regulation of Adrb1 18 0.44 4.45 8.93
162 INT7572 Regulation of Crhr1 8 0.45 5.6 8.93
163 INT22083 Regulation of Pth 55 0.62 22.32 8.9
164 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
165 INT17701 Gene_expression of PTHLH 103 0.78 64.23 8.85
166 INT684 Binding of AVP 38 0.48 13.9 8.85
167 INT10879 Positive_regulation of Avp 39 0.65 14.01 8.76
168 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62
169 INT3658 Regulation of Gcg 28 0.53 12.89 8.58
170 INT96 Binding of Adrb1 18 0.48 2.8 8.52
171 INT16735 Localization of Drd1a 11 0.61 0.35 8.42
172 INT15529 Gene_expression of GCG 51 0.75 18.55 8.35
173 INT23209 Binding of Adora2a 17 0.38 2.04 8.35
174 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
175 INT6625 Negative_regulation of Pth 96 0.58 57.6 8.24
176 INT13739 Positive_regulation of Positive_regulation of Avp 18 0.70 4.78 8.2
177 INT953 Positive_regulation of Positive_regulation of GHRH 17 0.67 2.38 8.18
178 INT52116 Regulation of Adcyap1 20 0.53 6.1 8.14
179 INT84765 Positive_regulation of Mc1r 24 0.70 5.95 8.01
180 INT5498 Positive_regulation of Positive_regulation of Crh 19 0.70 9.82 7.97
181 INT21179 Negative_regulation of Crh 22 0.58 8.03 7.87
182 INT64449 Negative_regulation of Gene_expression of Mc4r 7 0.58 2 7.86
183 INT26115 Gene_expression of Adrb1 14 0.64 5.13 7.78
184 INT54755 Negative_regulation of Adora2a 17 0.58 2.7 7.75
185 INT23992 Positive_regulation of Adrb1 25 0.56 4.01 7.62
186 INT7570 Transcription of Crhr1 7 0.66 6.6 7.6
187 INT2587 Regulation of Localization of Gcg 22 0.60 1.73 7.59
188 INT65964 Regulation of Adcyap1 13 0.45 10.1 7.54
189 INT74326 Gene_expression of Crhr1 25 0.66 9.7 7.48
190 INT3659 Negative_regulation of Gcg 26 0.51 10.08 7.39
191 INT216752 Binding of ADORA2B 17 0.36 0.76 7.36
192 INT91609 Regulation of Gene_expression of MC1R 11 0.62 2.75 7.34
193 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
194 INT80161 Positive_regulation of Crhr1 13 0.67 9.66 7.33
195 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
196 INT186142 Gene_expression of Ghrh 45 0.66 34.04 6.94
197 INT19806 Regulation of Avp 29 0.53 14.17 6.94
198 INT22336 Positive_regulation of Transcription of Crh 18 0.68 4.61 6.91
199 INT22369 Negative_regulation of Drd1a 15 0.47 6.13 6.87
200 INT7925 Transcription of Ghrh 13 0.67 2.36 6.77
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