GO:0030823

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Name regulation of cGMP metabolic process
Categary Process
Go Slim No
Go Link GO:0030823
Unique Molecular Interactions 59
Total Molecular Interactions 81
Total Single Events 1811
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of cGMP metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for regulation of cGMP metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT15578 GNRH1 Regulation of Localization of Lhb 3 0.07 0 1.22
2 INT52562 Lhb Positive_regulation of Prl 3 0.00 1.09 1.02
3 INT15577 Lhb Positive_regulation of GNRH1 1 0.14 0 0.88
4 INT52561 Trh Positive_regulation of Localization of Lhb 1 0.01 0.14 0.77
5 INT57295 nma Positive_regulation of Lhb 1 0.20 0 0.77
6 INT40127 Lhb Regulation of Localization of PRL 1 0.20 0.41 0.75
7 INT40126 PRL Regulation of Localization of Lhb 1 0.20 0.41 0.75
8 INT17623 Gnrh1 Positive_regulation of Localization of Lhb 4 0.72 1.46 0.71
9 INT32722 Prl Regulation of Lhb 1 0.02 0 0.6
10 INT56116 Agt Positive_regulation of Lhb 1 0.15 0 0.58
11 INT19879 Regulation of GNRH1 Regulation of Lhb 1 0.05 0 0.53
12 INT5132 GNRH1 Regulation of Lhb 2 0.08 0 0.52
13 INT261498 CBS Positive_regulation of DSE 1 0.00 0 0.5
14 INT17622 Ass1 Positive_regulation of Lhb 1 0.02 1.22 0.49
15 INT21778 crf Regulation of Localization of Lhb 1 0.02 0.34 0.49
16 INT58356 Gabrg1 Regulation of Localization of Lhb 1 0.01 0 0.48
17 INT280189 Binding of Cbs and P2rx3 1 0.01 1.03 0.47
18 INT280188 Binding of Cbs and Trpv1 1 0.26 1.03 0.47
19 INT76541 Prl Regulation of Localization of Lhb 1 0.12 0 0.41
20 INT27451 OPRM1 Positive_regulation of Localization of Lhb 1 0.01 0.1 0.41
21 INT45797 ZBTB7A Regulation of Lhb 1 0.36 0.09 0.38
22 INT45798 TRH Regulation of Lhb 1 0.36 0.09 0.38
23 INT261499 CBS Positive_regulation of CNR1 1 0.01 0.48 0.35
24 INT17301 Binding of CGA and Lhb 1 0.00 0 0.33
25 INT280190 Cbs Regulation of Gene_expression of Hist1h1t 1 0.04 0.58 0.32
26 INT21513 Negative_regulation of GNRH1 Negative_regulation of Lhb 1 0.05 0.14 0.32
27 INT56115 Agt Regulation of Lhb 1 0.16 0 0.32
28 INT17162 Binding of CEL and Lhb 1 0.06 0.38 0.3
29 INT64835 Binding of Lhb and Prl 1 0.08 0 0.27
30 INT68479 Gnrh1 Regulation of Lhb 1 0.00 1.58 0.25
31 INT41588 Binding of AGT and Lhb 1 0.00 0 0.24
32 INT7247 Binding of GNRH1 and Lhb 2 0.08 0 0.22
33 INT73168 Lhb Positive_regulation of Gh 2 0.00 0.95 0.2
34 INT19105 Olr824 Negative_regulation of Lhb 1 0.00 0 0.2
35 INT92093 Lhb Positive_regulation of Localization of POMC 1 0.01 1.88 0.17
36 INT74070 Trh Regulation of Lhb 1 0.02 0.27 0.15
37 INT68480 Negative_regulation of Gnrh1 Regulation of Lhb 1 0.00 0.67 0.15
38 INT16104 GNRH1 Positive_regulation of Lhb 2 0.03 0.53 0.14
39 INT43781 Lhb Positive_regulation of Rtcd1 1 0.00 0.06 0.14
40 INT73167 Regulation of Lhb Positive_regulation of Gh 1 0.00 0.48 0.1
41 INT25285 CBS Negative_regulation of Localization of IL1RL1 1 0.05 0 0.09
42 INT45834 CGA Negative_regulation of Localization of Lhb 1 0.00 0 0.08
43 INT27738 CBS Positive_regulation of EGF 1 0.33 0.85 0.05
44 INT27737 CBS Positive_regulation of Positive_regulation of EGF 1 0.36 0.85 0.05
45 INT196435 Lhb Positive_regulation of Mapk1 1 0.12 0.77 0.04
46 INT270432 Lhb Positive_regulation of APP 1 0.03 0.51 0.03
47 INT55914 GNRH1 Positive_regulation of Localization of Lhb 1 0.13 0 0
48 INT299447 Lhb Positive_regulation of Gene_expression of Odc1 1 0.24 0.3 0
49 INT17527 Igf1 Regulation of Lhb 1 0.00 0 0
50 INT187623 Lhb Regulation of Gene_expression of Pparg 1 0.02 0.09 0
51 INT16100 Gnrh1 Positive_regulation of Localization of Lhb 1 0.06 0.13 0
52 INT17531 Lhb Regulation of Gh 1 0.00 0 0
53 INT344891 Lhb Positive_regulation of Gene_expression of Ptger2 1 0.19 0.09 0
54 INT17525 Ghsr Regulation of Lhb 1 0.01 0 0
55 INT16101 Gnrh1 Positive_regulation of Lhb 1 0.06 0.12 0
56 INT299445 Lhb Positive_regulation of Gene_expression of Nr4a2 1 0.22 0.13 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of cGMP metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in regulation of cGMP metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5127 Localization of Lhb 488 0.80 50.48 162.66
2 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26
3 INT5710 Negative_regulation of Localization of Lhb 146 0.57 20.51 58.33
4 INT6299 Regulation of Localization of Lhb 104 0.61 8.98 48.79
5 INT847 Regulation of Lhb 131 0.61 22.08 46.54
6 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81
7 INT5711 Positive_regulation of Localization of Lhb 90 0.70 10.92 36.76
8 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04
9 INT130497 Gene_expression of Cbs 5 0.77 16.93 9.34
10 INT261511 Localization of CBS 1 0.02 5.06 7.27
11 INT5126 Positive_regulation of Positive_regulation of Lhb 16 0.48 2.12 5.23
12 INT4283 Positive_regulation of Cbs 10 0.46 6.85 4.44
13 INT29424 Negative_regulation of Positive_regulation of Lhb 21 0.56 4.58 4.03
14 INT280193 Positive_regulation of Gene_expression of Cbs 1 0.69 6.59 3.81
15 INT7224 Positive_regulation of Gene_expression of Lhb 18 0.45 10.22 3.4
16 INT7232 Regulation of Negative_regulation of Lhb 9 0.45 3.63 3.29
17 INT19844 Negative_regulation of Gene_expression of Lhb 12 0.51 3.19 2.97
18 INT19843 Positive_regulation of Negative_regulation of Lhb 5 0.48 0.58 2.18
19 INT5129 Regulation of Gene_expression of Lhb 10 0.55 4.79 2.09
20 INT17941 Positive_regulation of Regulation of Lhb 4 0.63 0.36 2.09
21 INT11770 Binding of Lhb 14 0.48 3.57 1.91
22 INT31981 Regulation of Regulation of Lhb 4 0.44 1.03 1.57
23 INT34626 Binding of Cbs 2 0.37 3.27 1.27
24 INT144645 Localization of Cbs 2 0.64 1.02 1.22
25 INT54367 Regulation of Positive_regulation of Lhb 3 0.26 0 1.15
26 INT4971 Regulation of Cbs 2 0.44 1.66 1
27 INT261514 Positive_regulation of Localization of CBS 1 0.01 0.67 0.91
28 INT202190 Gene_expression of CBS 7 0.32 4.19 0.88
29 INT280194 Regulation of Gene_expression of Cbs 1 0.61 1.54 0.73
30 INT21746 Negative_regulation of Negative_regulation of Lhb 2 0.24 0.83 0.68
31 INT261508 Negative_regulation of CBS 1 0.01 0.39 0.61
32 INT261515 Positive_regulation of CBS 2 0.47 2.63 0.41
33 INT111345 Negative_regulation of Cbs 2 0.30 2.82 0.36
34 INT259859 Regulation of CBS 1 0.01 1.26 0.34
35 INT259857 Regulation of Gene_expression of CBS 1 0.01 1.07 0.27
36 INT58668 Negative_regulation of Regulation of Lhb 2 0.41 0.8 0.19
37 INT259858 Protein_catabolism of CBS 1 0.03 1.46 0.14
38 INT214761 Positive_regulation of Binding of Lhb 1 0.15 0 0
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