GO:0030903

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Name notochord development
Categary Process
Go Slim No
Go Link GO:0030903
Unique Molecular Interactions 51
Total Molecular Interactions 62
Total Single Events 721
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for notochord development. They are ordered first by their pain relevance and then by number of times they were reported for notochord development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
2 INT59396 Tead1 Negative_regulation of Negative_regulation of Man2a2 1 0.00 0 0.86
3 INT59395 Tead1 Negative_regulation of Man2a2 1 0.00 0 0.86
4 INT287099 Binding of Bdnf and T 1 0.10 1.1 0.69
5 INT88142 Pt Positive_regulation of 1700061J05Rik 1 0.04 1.08 0.66
6 INT202043 MMP13 Regulation of Protein_catabolism of COL2A1 1 0.01 0.54 0.54
7 INT135755 Pomc Positive_regulation of Positive_regulation of Id3 1 0.17 0 0.5
8 INT135752 Pomc Positive_regulation of Id3 1 0.16 0 0.5
9 INT312122 ELANE Positive_regulation of Protein_catabolism of COL2A1 1 0.05 0.65 0.39
10 INT204793 T Positive_regulation of Mthfd1 1 0.00 1.32 0.39
11 INT340609 Bdnf Regulation of Gene_expression of Wnt3a 1 0.53 0.31 0.36
12 INT264523 PTGDS Positive_regulation of Gene_expression of COL2A1 1 0.03 1.24 0.3
13 INT220194 PTGER2 Negative_regulation of COL2A1 1 0.26 0.55 0.29
14 INT287098 Binding of FL and T 1 0.10 0.66 0.23
15 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
16 INT287097 T Positive_regulation of Ntrk2 1 0.21 0.6 0.19
17 INT220190 PTGER2 Regulation of COL2A1 1 0.32 0.92 0.18
18 INT220191 Binding of COL2A1 and PTGER2 1 0.22 0.35 0.18
19 INT30068 Tead1 Positive_regulation of Localization of Avp 1 0.04 0 0.16
20 INT340608 Binding of Creb1 and Wnt3a 1 0.30 0.24 0.14
21 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14
22 INT220213 Mmp13 Regulation of Protein_catabolism of COL2A1 1 0.49 0.29 0.14
23 INT226532 T Positive_regulation of Gene_expression of IFNA1 1 0.01 0.15 0.12
24 INT326974 BMP2 Positive_regulation of Gene_expression of COL2A1 1 0.07 0.27 0.11
25 INT220195 PTGER2 Negative_regulation of Localization of COL2A1 1 0.26 0.51 0.09
26 INT288003 Binding of COL2A1 and PADI1 1 0.09 0.11 0.06
27 INT220189 Binding of COL2A1 and TIMP1 1 0.04 0.1 0.05
28 INT306238 Tead1 Regulation of Ins1 1 0.00 1.04 0.05
29 INT323807 NFAT5 Regulation of Gene_expression of COL2A1 1 0.29 0.19 0.04
30 INT220196 Binding of PTGER2 and Negative_regulation of Gene_expression of COL2A1 1 0.26 0.77 0.04
31 INT184208 IL1B Negative_regulation of SOX9 1 0.32 0 0.03
32 INT233397 Binding of ABCA4 and COL2A1 1 0.38 3.59 0.03
33 INT220245 IL1RN Regulation of Protein_catabolism of COL2A1 1 0.09 0 0.03
34 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0
35 INT320029 Gene_expression of SOX9 Positive_regulation of Gene_expression of COL7A1 1 0.03 0 0
36 INT245726 SOX9 Regulation of SGCG 1 0.00 0.29 0
37 INT333879 Shc1 Positive_regulation of SOX9 1 0.01 0 0
38 INT251072 Wnt3a Positive_regulation of Axin2 1 0.23 0.29 0
39 INT288002 Binding of COL2A1 and GOPC 1 0.12 0 0
40 INT312230 INPP5K Regulation of Gene_expression of COL2A1 1 0.06 0 0
41 INT326893 Binding of Tcf4 and Wnt3a 1 0.13 0 0
42 INT326896 Wnt3a Positive_regulation of Transcription of PLD2 1 0.24 0.06 0
43 INT88567 COL2A1 Positive_regulation of A1cf 1 0.09 0.36 0
44 INT312227 INPP5K Regulation of Negative_regulation of COL2A1 1 0.06 0 0
45 INT251070 Wnt3a Positive_regulation of Cldn3 1 0.30 0.29 0
46 INT326894 Wnt3a Positive_regulation of Transcription of Pld1 1 0.24 0.06 0
47 INT312345 Binding of COL2A1 and COL5A2 1 0.00 1.21 0
48 INT323804 NFAT5 Regulation of Transcription of COL2A1 1 0.43 0.07 0
49 INT312213 INPP5K Regulation of COL2A1 1 0.06 0 0
50 INT249606 Slc25a1 Positive_regulation of Sd 1 0.05 0 0
51 INT245735 SOX9 Regulation of COL5A2 1 0.07 0.29 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for notochord development. They are ordered first by their pain relevance and then by number of times they were reported in notochord development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58
2 INT130731 Protein_catabolism of COL2A1 47 0.96 21.86 9.28
3 INT340600 Gene_expression of Wnt3a 1 0.68 2.14 9.14
4 INT20552 Negative_regulation of Gene_expression of COL2A1 29 0.56 11.92 4.81
5 INT204449 Gene_expression of T 17 0.32 9.77 4.77
6 INT217742 Positive_regulation of Gene_expression of COL2A1 20 0.67 9.76 4.23
7 INT340603 Regulation of Gene_expression of Wnt3a 1 0.54 0.49 3.75
8 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47
9 INT130729 Negative_regulation of Protein_catabolism of COL2A1 15 0.42 7.59 3.35
10 INT340595 Positive_regulation of Gene_expression of Wnt3a 1 0.61 0.86 3.11
11 INT20551 Negative_regulation of COL2A1 31 0.55 21.98 2.66
12 INT96693 Binding of COL2A1 45 0.46 37.11 2.61
13 INT53434 Positive_regulation of T 7 0.07 3.67 2.09
14 INT39783 Positive_regulation of Sd 3 0.36 0.41 1.86
15 INT340596 Negative_regulation of Gene_expression of Wnt3a 1 0.51 0.38 1.4
16 INT39781 Gene_expression of Sd 7 0.60 2.47 1.33
17 INT117232 Localization of COL2A1 11 0.72 7.34 1.3
18 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2
19 INT226407 Negative_regulation of T 2 0.21 1.81 1.18
20 INT11658 Regulation of Gene_expression of COL2A1 9 0.62 3.09 1.11
21 INT33207 Gene_expression of Pt 9 0.53 0.93 1.08
22 INT208427 Regulation of T 3 0.25 3.28 1.08
23 INT340604 Regulation of Wnt3a 1 0.24 0 0.95
24 INT287093 Positive_regulation of Gene_expression of T 1 0.28 1.47 0.86
25 INT287090 Regulation of Gene_expression of T 1 0.18 2.77 0.86
26 INT42339 Gene_expression of Tead1 4 0.31 0.56 0.8
27 INT287094 Transcription of T 1 0.29 1.41 0.8
28 INT66992 Positive_regulation of Id3 2 0.43 0.23 0.78
29 INT57881 Binding of Tead1 2 0.25 1.63 0.7
30 INT226411 Binding of T 2 0.15 1.56 0.68
31 INT31653 Positive_regulation of Tead1 4 0.47 0.25 0.66
32 INT184222 Negative_regulation of SOX9 7 0.41 2.68 0.58
33 INT157103 Transcription of SOX9 6 0.59 1.2 0.58
34 INT157104 Positive_regulation of SOX9 6 0.66 1.66 0.52
35 INT157105 Positive_regulation of Transcription of SOX9 4 0.58 0.88 0.51
36 INT135747 Gene_expression of Id3 1 0.52 0 0.5
37 INT340598 Binding of Wnt3a 1 0.33 0.15 0.46
38 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44
39 INT287095 Negative_regulation of Gene_expression of T 1 0.24 0.47 0.41
40 INT340606 Positive_regulation of Wnt3a 1 0.61 0.49 0.4
41 INT180577 Positive_regulation of Protein_catabolism of COL2A1 2 0.12 0.91 0.31
42 INT29080 Binding of Pt 1 0.03 0.09 0.31
43 INT220209 Negative_regulation of Localization of COL2A1 1 0.41 0.48 0.29
44 INT51514 Positive_regulation of Wnt3a 3 0.04 3.32 0.28
45 INT29305 Positive_regulation of Pt 6 0.37 0.73 0.27
46 INT245763 Regulation of SOX9 4 0.43 1.68 0.21
47 INT70176 Negative_regulation of Sd 1 0.05 0.28 0.21
48 INT134662 Positive_regulation of Gene_expression of SOX9 9 0.48 1.69 0.19
49 INT90480 Negative_regulation of Tead1 4 0.37 1.37 0.18
50 INT220208 Regulation of Protein_catabolism of COL2A1 1 0.26 0.28 0.17
51 INT309524 Regulation of Pt 1 0.05 0 0.16
52 INT51512 Negative_regulation of Positive_regulation of Wnt3a 1 0.04 1.3 0.13
53 INT51513 Positive_regulation of Positive_regulation of Wnt3a 1 0.04 1.31 0.13
54 INT221000 Phosphorylation of COL2A1 1 0.19 0.18 0.12
55 INT309526 Negative_regulation of Gene_expression of Pt 1 0.05 0 0.11
56 INT309525 Regulation of Gene_expression of Pt 1 0.05 0 0.11
57 INT184220 Negative_regulation of Gene_expression of SOX9 4 0.36 0.58 0.09
58 INT214463 Binding of Wnt3a 2 0.26 0.23 0.08
59 INT250505 Positive_regulation of Negative_regulation of COL2A1 1 0.41 0.57 0.05
60 INT272249 Negative_regulation of Negative_regulation of COL2A1 1 0.06 0 0.05
61 INT69474 Protein_catabolism of T 1 0.64 0 0.04
62 INT313405 Positive_regulation of Localization of Pt 1 0.19 0 0.03
63 INT249932 Negative_regulation of Pt 1 0.08 0.1 0.03
64 INT342197 Transcription of Pt 1 0.54 0.3 0.03
65 INT313411 Localization of Pt 1 0.29 0 0.03
66 INT342203 Negative_regulation of Transcription of Pt 1 0.33 0.3 0.03
67 INT214538 Binding of Sd 6 0.26 1.31 0
68 INT184729 Transcription of COL2A1 4 0.67 1.1 0
69 INT162339 Regulation of Gene_expression of SOX9 4 0.32 0.42 0
70 INT245757 Localization of SOX9 4 0.62 0.8 0
71 INT214465 Localization of Wnt3a 2 0.52 0.29 0
72 INT251053 Gene_expression of Wnt3a 2 0.47 0.5 0
73 INT165862 Positive_regulation of Binding of COL2A1 2 0.43 0 0
74 INT326853 Positive_regulation of Gene_expression of Wnt3a 1 0.36 0.2 0
75 INT312246 Regulation of Negative_regulation of COL2A1 1 0.07 0 0
76 INT306234 Localization of Tead1 1 0.01 0.22 0
77 INT251054 Regulation of Localization of Wnt3a 1 0.27 0.07 0
78 INT323815 Negative_regulation of Transcription of SOX9 1 0.41 0.18 0
79 INT245752 Positive_regulation of Binding of SOX9 1 0.41 0.48 0
80 INT251066 Regulation of Gene_expression of Wnt3a 1 0.31 0.07 0
81 INT322897 Negative_regulation of Transcription of COL2A1 1 0.17 0 0
82 INT281642 Localization of Sd 1 0.26 0 0
83 INT245765 Binding of SOX9 1 0.31 0.87 0
84 INT312245 Positive_regulation of Localization of SOX9 1 0.10 0 0
85 INT326843 Negative_regulation of Gene_expression of Wnt3a 1 0.22 0.29 0
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