GO:0030949

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Name positive regulation of vascular endothelial growth factor receptor signaling pathway
Categary Process
Go Slim No
Go Link GO:0030949
Unique Molecular Interactions 978
Total Molecular Interactions 1574
Total Single Events 11405
Pain Genes Associated 23

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of vascular endothelial growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of vascular endothelial growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT95068 Tlr4 Positive_regulation of IL1B 1 0.03 4.54 5.6
2 INT128296 Negative_regulation of IL1B Positive_regulation of Insr 1 0.10 1.36 4.52
3 INT128295 IL1B Positive_regulation of Insr 1 0.11 1.36 4.5
4 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48
5 INT64719 IL1B Positive_regulation of IL6 7 0.41 6.84 3.14
6 INT130721 Binding of IL1B and IL1RN 6 0.05 5.29 2.85
7 INT209924 IL1B Negative_regulation of PPARA 1 0.20 4.38 2.17
8 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
9 INT51051 IL1B Positive_regulation of Localization of IL6 7 0.57 3.79 1.87
10 INT81920 Binding of IL1B and NFKB1 1 0.04 1.54 1.85
11 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
12 INT24817 Binding of POMC and VTN 8 0.42 0.39 1.71
13 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65
14 INT83093 IL1B Positive_regulation of BDKRB1 1 0.51 0.44 1.65
15 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63
16 INT74937 IL1B Positive_regulation of CPOX 5 0.18 1.13 1.55
17 INT91456 IL1B Positive_regulation of Gene_expression of CPOX 6 0.17 3.36 1.53
18 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
19 INT197111 Binding of IL1B and MCF2 1 0.02 2.12 1.4
20 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
21 INT95093 ITIH4 Positive_regulation of IL1B 1 0.43 1.04 1.32
22 INT95094 Negative_regulation of ITIH4 Positive_regulation of IL1B 1 0.36 1.04 1.32
23 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
24 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
25 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
26 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
27 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
28 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
29 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
30 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
31 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
32 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
33 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
34 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
35 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
36 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
37 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
38 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
39 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
40 INT65986 IL1B Positive_regulation of PTGS2 3 0.32 2.05 1.03
41 INT271875 IL1RN Negative_regulation of Binding of IL1B 1 0.01 1.3 1.01
42 INT102690 IL1B Positive_regulation of ITGAL 1 0.05 0.87 0.99
43 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
44 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98
45 INT154255 Tnf Positive_regulation of IL1B 1 0.54 0.94 0.97
46 INT240123 MIR885 Negative_regulation of IL1B 1 0.01 1.57 0.96
47 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
48 INT130722 Binding of IL1B and Nfkb1 1 0.28 1.23 0.95
49 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
50 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
51 INT130725 Binding of IL1B and Il1rn 1 0.01 1.16 0.93
52 INT81919 Binding of HSF1 and IL1B 1 0.42 0.77 0.93
53 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
54 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87
55 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87
56 INT196632 IL1B Positive_regulation of F2RL1 2 0.05 1.52 0.84
57 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
58 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
59 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
60 INT65011 IL1B Positive_regulation of PTGER2 4 0.08 0.92 0.82
61 INT83094 IL1B Positive_regulation of Positive_regulation of BDKRB1 1 0.45 0.2 0.81
62 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76
63 INT113549 Binding of VTN and alphavbeta3 integrin receptor 1 0.09 2.05 0.76
64 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75
65 INT278958 LEP Positive_regulation of IL1B 1 0.33 1.91 0.74
66 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
67 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
68 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
69 INT74941 IL1B Positive_regulation of Gene_expression of PTGER2 1 0.08 0.48 0.72
70 INT65985 IL1B Positive_regulation of Gene_expression of PTGS2 3 0.23 2.62 0.71
71 INT73822 TAC1 Positive_regulation of Localization of IL1B 1 0.04 0.56 0.71
72 INT73824 TFF2 Positive_regulation of Localization of IL1B 1 0.02 0.56 0.71
73 INT113500 IL1B Positive_regulation of Gene_expression of BHLHE23 1 0.18 0.1 0.71
74 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
75 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
76 INT95148 CEL Regulation of IL1B 1 0.24 0.88 0.7
77 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
78 INT334395 IL1B Positive_regulation of Tnf 1 0.11 2.83 0.69
79 INT250932 IL1B Regulation of Gene_expression of BDNF 1 0.06 0.24 0.69
80 INT346233 PREP Regulation of IL1B 1 0.05 1.44 0.69
81 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
82 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68
83 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68
84 INT66537 IL1B Positive_regulation of Gene_expression of Fos 1 0.02 0 0.68
85 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
86 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
87 INT194857 Positive_regulation of Adora2a Positive_regulation of Gene_expression of Vegfa 1 0.23 0.74 0.67
88 INT70998 IL1B Regulation of Gene_expression of Icam1 1 0.44 0.95 0.67
89 INT88194 ZAK Positive_regulation of Gene_expression of IL1B 1 0.07 0.94 0.66
90 INT152111 IL1B Negative_regulation of Ltp 1 0.03 0.85 0.66
91 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66
92 INT116441 IL1B Positive_regulation of Gene_expression of CCL2 2 0.04 0.62 0.65
93 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
94 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
95 INT172139 IL4 Negative_regulation of IL1B 1 0.02 0.85 0.63
96 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
97 INT176475 IL1B Positive_regulation of Gene_expression of ICAM1 1 0.02 0.56 0.62
98 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
99 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
100 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61
101 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
102 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
103 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
104 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
105 INT285467 Negative_regulation of Binding of IL1B and IL1RN 1 0.05 1.33 0.61
106 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
107 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
108 INT81915 HSF1 Negative_regulation of IL1B 1 0.51 0.65 0.59
109 INT81917 HSF1 Positive_regulation of IL1B 1 0.41 0.65 0.59
110 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
111 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
112 INT58342 Calca Negative_regulation of Localization of IL1B 1 0.00 0.6 0.58
113 INT54620 IL1B Positive_regulation of Crh 1 0.01 0.39 0.58
114 INT176471 TNF Positive_regulation of Gene_expression of IL1B 1 0.02 0.61 0.57
115 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
116 INT108387 IL1B Positive_regulation of Localization of MMP1 1 0.27 0.3 0.57
117 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
118 INT260845 Binding of Flt1 and Positive_regulation of Gene_expression of TNF 1 0.36 1.5 0.56
119 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
120 INT204087 IL1B Positive_regulation of Gene_expression of LEP 1 0.09 2.6 0.54
121 INT194918 Csf2 Positive_regulation of Gene_expression of VEGFA 1 0.02 0.85 0.52
122 INT194919 Kitl Positive_regulation of Gene_expression of VEGFA 1 0.01 0.85 0.52
123 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51
124 INT254356 Binding of IFNG and IL1B 1 0.00 1.87 0.51
125 INT254357 Binding of IFNA1 and IL1B 1 0.00 1.88 0.51
126 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51
127 INT250933 IL1B Positive_regulation of Gene_expression of BDNF 1 0.10 0.27 0.5
128 INT64720 Regulation of IL1B Positive_regulation of IL6 1 0.36 0.65 0.5
129 INT210878 Binding of FLT1 and HBM 1 0.06 0.83 0.5
130 INT127430 VEGFA Negative_regulation of Gene_expression of TIMP1 1 0.43 0.6 0.5
131 INT20546 IL1B Regulation of Gene_expression of SGCG 1 0.65 0.14 0.5
132 INT106074 IL1B Positive_regulation of Gene_expression of A2M 1 0.03 0.75 0.49
133 INT225025 IL1B Positive_regulation of Positive_regulation of Cxcl1 1 0.04 0.32 0.49
134 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
135 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49
136 INT94262 IL1B Positive_regulation of Localization of PTGER2 1 0.22 0.8 0.49
137 INT288376 IL17A Regulation of VEGFA 1 0.00 1.16 0.49
138 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48
139 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48
140 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48
141 INT305547 VEGFA Positive_regulation of Gtf3a 2 0.00 1.83 0.48
142 INT260836 Il18 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.48
143 INT300960 Il4 Negative_regulation of IL1B 1 0.03 0.37 0.48
144 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48
145 INT130726 Negative_regulation of Binding of IL1B and Il1rn 1 0.01 0.6 0.48
146 INT331928 Negative_regulation of Cpox Negative_regulation of VEGFA 1 0.01 0.97 0.47
147 INT148818 IL1B Regulation of Gene_expression of TNC 1 0.29 0.57 0.47
148 INT314053 VEGFA Positive_regulation of Gene_expression of Mmp2 1 0.02 0.2 0.47
149 INT135176 Myst2 Regulation of Gene_expression of Hif1a 1 0.24 0.47 0.47
150 INT260843 Il6 Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
151 INT260838 Il17a Positive_regulation of Localization of VEGFA 1 0.06 1.67 0.47
152 INT106073 IL1B Positive_regulation of Positive_regulation of NFKB1 1 0.41 0.7 0.47
153 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
154 INT138154 IL1B Positive_regulation of Transcription of Mmp2 1 0.04 0.23 0.46
155 INT224698 Il17a Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
156 INT138160 IL1B Positive_regulation of Gene_expression of Mmp3 1 0.03 0.23 0.46
157 INT224699 Il18 Positive_regulation of Gene_expression of VEGFA 1 0.01 0.49 0.46
158 INT106001 Binding of PLAUR and VTN 2 0.23 1.5 0.45
159 INT224451 Il1 Positive_regulation of Gene_expression of VEGFA 1 0.10 1.08 0.45
160 INT197113 RETNLB Regulation of IL1B 1 0.00 1.27 0.44
161 INT48716 IL1B Regulation of Gene_expression of SERPINE1 1 0.42 0.59 0.44
162 INT224434 TNF Positive_regulation of VEGFA 1 0.10 2.04 0.44
163 INT135178 Myst2 Regulation of Hif1a 1 0.24 0.44 0.44
164 INT172149 IL17A Positive_regulation of Gene_expression of IL1B 1 0.01 0.5 0.43
165 INT311587 CXCL10 Regulation of Gene_expression of VEGFA 1 0.23 0.45 0.43
166 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43
167 INT311589 EGF Regulation of Gene_expression of VEGFA 1 0.18 0.51 0.43
168 INT60063 IL1B Regulation of NPEPPS 1 0.00 0.29 0.42
169 INT254350 FASLG Negative_regulation of Gene_expression of VEGFA 1 0.06 0.92 0.42
170 INT153720 Binding of VEGFA and Pscs 1 0.32 3.12 0.41
171 INT107704 IL1B Positive_regulation of Localization of RELA 1 0.02 0.13 0.41
172 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41
173 INT346238 PREP Negative_regulation of IL1B 1 0.04 0.99 0.41
174 INT107699 IL1B Positive_regulation of Localization of NFKB1 1 0.03 0.13 0.41
175 INT146476 IL1B Regulation of Gene_expression of HAS1 1 0.30 0.35 0.4
176 INT298584 IL1B Regulation of Gene_expression of TNFRSF11B 1 0.22 0.7 0.4
177 INT346148 Binding of ADM and VTN 1 0.15 0.93 0.39
178 INT278944 ZEB1 Negative_regulation of IL1B 1 0.00 1.09 0.39
179 INT346142 Positive_regulation of Binding of ADM and VTN 1 0.20 0.93 0.39
180 INT285750 IL1B Positive_regulation of Localization of PRL 1 0.05 1.51 0.39
181 INT304319 Ptger1 Positive_regulation of Gene_expression of Vegfa 1 0.37 1.19 0.39
182 INT285744 IL1B Regulation of Localization of PRL 1 0.05 1.51 0.39
183 INT227906 IL10 Regulation of Gene_expression of IL1B 1 0.07 0.57 0.38
184 INT285205 Binding of VEGFA and SLEB1 1 0.05 5.12 0.38
185 INT113551 Binding of ITGA3 and VTN 1 0.02 1.03 0.38
186 INT264527 IL1B Positive_regulation of Gene_expression of PTGDS 1 0.07 0.75 0.38
187 INT182497 IL1B Regulation of Localization of GH1 1 0.00 0.84 0.38
188 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38
189 INT342623 Binding of VEGFA and Col18a1 1 0.02 1.15 0.37
190 INT342606 Binding of MMP14 and VEGFA 1 0.08 1.16 0.37
191 INT113555 Negative_regulation of Binding of FN1 and VTN 1 0.23 0.87 0.37
192 INT224582 Binding of IL1B and Positive_regulation of Gene_expression of TNF 1 0.05 1.33 0.37
193 INT277353 VEGFA Regulation of Mtor 1 0.02 1.11 0.37
194 INT113559 Binding of PLAU and VTN 1 0.28 0.82 0.37
195 INT113554 Negative_regulation of Binding of PLAU and VTN 1 0.32 0.87 0.37
196 INT277355 VEGFA Regulation of Trerf1 1 0.08 1.17 0.37
197 INT277354 Gene_expression of VEGFA Regulation of Mtor 1 0.02 1.1 0.37
198 INT277352 Gene_expression of VEGFA Regulation of Trerf1 1 0.08 1.16 0.37
199 INT322015 Binding of IL1B and P2RX7 1 0.07 1 0.37
200 INT113547 Negative_regulation of Binding of PLAUR and VTN 1 0.26 0.87 0.37

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of vascular endothelial growth factor receptor signaling pathway. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of vascular endothelial growth factor receptor signaling pathway. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97
2 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
3 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9
4 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
5 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35
6 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
7 INT6849 Localization of IL1B 229 0.81 112.56 69.63
8 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86
9 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
10 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82
11 INT5973 Regulation of IL1B 109 0.62 66.6 39.88
12 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
13 INT6484 Binding of IL1B 122 0.47 75.84 35.07
14 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
15 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
16 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
17 INT9237 Regulation of Gene_expression of IL1B 49 0.62 30.69 20.34
18 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
19 INT36054 Transcription of IL1B 53 0.72 32.64 17.31
20 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
21 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89
22 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
23 INT25266 Positive_regulation of Localization of IL1B 38 0.69 15.89 14.35
24 INT19191 Negative_regulation of Localization of IL1B 35 0.58 15.19 13.63
25 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
26 INT103154 Gene_expression of FLT1 138 0.76 58.5 7.41
27 INT134624 Gene_expression of Flt1 77 0.66 48.86 7.27
28 INT11378 Negative_regulation of Positive_regulation of IL1B 23 0.59 10.28 7.26
29 INT36053 Positive_regulation of Positive_regulation of IL1B 22 0.70 11.41 6.84
30 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63
31 INT135170 Positive_regulation of Hif1a 86 0.67 99.4 6.07
32 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
33 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
34 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68
35 INT112713 Gene_expression of Hif1a 24 0.75 20.48 5.45
36 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44
37 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
38 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
39 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23
40 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
41 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
42 INT19190 Regulation of Localization of IL1B 14 0.50 8.71 4.12
43 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09
44 INT118835 Positive_regulation of Vegfa 18 0.59 11.2 3.91
45 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
46 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
47 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
48 INT137609 Localization of Vegfa 22 0.78 14.67 3.01
49 INT24821 Binding of VTN 14 0.47 5.83 3
50 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
51 INT6479 Negative_regulation of Binding of IL1B 10 0.43 5.1 2.78
52 INT134756 Positive_regulation of Gene_expression of Hif1a 8 0.50 11.14 2.68
53 INT43719 Positive_regulation of Vegfa 21 0.69 5.15 2.64
54 INT11379 Positive_regulation of Negative_regulation of IL1B 9 0.49 7.2 2.64
55 INT15144 Protein_catabolism of IL1B 11 0.92 4.67 2.58
56 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
57 INT123528 Negative_regulation of Gene_expression of Vegfa 10 0.57 7.08 2.31
58 INT43723 Regulation of Vegfa 9 0.34 4.96 2.28
59 INT36055 Positive_regulation of Transcription of IL1B 9 0.49 6.24 2.21
60 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19
61 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
62 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
63 INT73906 Regulation of Transcription of IL1B 5 0.56 3.46 2.1
64 INT105247 Positive_regulation of Gene_expression of Vegfa 12 0.67 12.07 2.05
65 INT100371 Positive_regulation of Flt1 11 0.63 6.42 2.02
66 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
67 INT96881 Gene_expression of ARNT 8 0.50 3.27 1.98
68 INT64709 Gene_expression of VTN 11 0.67 11.01 1.97
69 INT171323 Phosphorylation of IL1B 5 0.57 4.13 1.94
70 INT143127 Positive_regulation of FLT1 44 0.66 21.7 1.92
71 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
72 INT14246 Regulation of Positive_regulation of IL1B 7 0.44 3.04 1.77
73 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73
74 INT118833 Positive_regulation of Gene_expression of Vegfa 11 0.65 8.14 1.7
75 INT116498 Negative_regulation of Negative_regulation of IL1B 7 0.41 3.08 1.7
76 INT12442 Localization of Vegfa 11 0.73 4.85 1.68
77 INT255663 Binding of Flt1 11 0.32 6.92 1.64
78 INT122597 Transcription of Hif1a 5 0.69 5.56 1.63
79 INT105248 Negative_regulation of Vegfa 8 0.47 6.19 1.61
80 INT153723 Negative_regulation of Gene_expression of Hif1a 2 0.41 1.25 1.58
81 INT73901 Negative_regulation of Transcription of IL1B 3 0.53 0.46 1.57
82 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51
83 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
84 INT89116 Regulation of Positive_regulation of VEGFA 8 0.43 6.62 1.5
85 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
86 INT109536 Negative_regulation of Vegfa 15 0.46 10.35 1.39
87 INT199550 Negative_regulation of Flt1 18 0.37 12.57 1.37
88 INT100373 Negative_regulation of Gene_expression of Flt1 11 0.53 10 1.37
89 INT232785 Localization of Hif1a 8 0.46 10.37 1.33
90 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28
91 INT24819 Positive_regulation of VTN 8 0.49 3.52 1.23
92 INT173114 Positive_regulation of Binding of IL1B 6 0.49 2.56 1.22
93 INT31572 Negative_regulation of FLT1 21 0.48 16.49 1.18
94 INT137607 Positive_regulation of Localization of Vegfa 7 0.49 3.72 1.18
95 INT188376 Negative_regulation of Gene_expression of Vegfa 5 0.30 5.29 1.18
96 INT134627 Positive_regulation of Gene_expression of Flt1 9 0.49 7.16 1.12
97 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
98 INT25264 Regulation of Negative_regulation of IL1B 3 0.27 1.17 1.02
99 INT346201 Negative_regulation of Phosphorylation of IL1B 1 0.20 1.69 1.01
100 INT112717 Negative_regulation of Binding of VEGFA 21 0.56 11.07 0.99
101 INT78014 Negative_regulation of ITGA5 1 0.01 1.71 0.98
102 INT156351 Positive_regulation of Flt1 22 0.51 20.05 0.91
103 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86
104 INT211488 Regulation of Binding of VEGFA 5 0.43 3.72 0.83
105 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
106 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
107 INT210247 Positive_regulation of Bmp4 6 0.65 4.36 0.8
108 INT135169 Binding of Hif1a 22 0.47 12.48 0.79
109 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79
110 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
111 INT143445 Protein_catabolism of VEGFA 12 0.85 4.14 0.72
112 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
113 INT12443 Regulation of Localization of Vegfa 2 0.20 0 0.72
114 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
115 INT233837 Negative_regulation of Hif1a 9 0.26 12.72 0.65
116 INT112708 Negative_regulation of Hif1a 5 0.38 2.7 0.64
117 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
118 INT340625 Protein_catabolism of Vegfa 1 0.05 1.61 0.64
119 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63
120 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
121 INT346193 Positive_regulation of Gene_expression of VTN 1 0.25 1.54 0.63
122 INT136465 Regulation of Hif1a 5 0.39 7.05 0.62
123 INT100374 Positive_regulation of Positive_regulation of Flt1 1 0.09 0.99 0.62
124 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
125 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
126 INT81352 Negative_regulation of Regulation of IL1B 2 0.41 0.51 0.58
127 INT296583 Gene_expression of Fgf10 3 0.59 2.64 0.57
128 INT296594 Regulation of Fgf10 1 0.15 1.53 0.56
129 INT174873 Regulation of Transcription of VEGFA 8 0.43 3.71 0.55
130 INT172964 Binding of Vegfa 14 0.47 10.62 0.53
131 INT135173 Regulation of Gene_expression of Hif1a 3 0.44 2.49 0.53
132 INT134758 Positive_regulation of Transcription of Hif1a 2 0.33 2.44 0.53
133 INT143125 Binding of FLT1 48 0.40 13.6 0.51
134 INT153065 Regulation of Hif1a 8 0.28 8.57 0.51
135 INT105677 Binding of Vegfa 7 0.37 5.22 0.51
136 INT255665 Localization of Flt1 5 0.63 7.65 0.51
137 INT109390 Regulation of Gene_expression of Flt1 4 0.41 4.08 0.51
138 INT153067 Positive_regulation of Positive_regulation of Hif1a 10 0.49 11.83 0.47
139 INT142124 Binding of Bmp4 1 0.35 0.46 0.45
140 INT158019 Positive_regulation of Gene_expression of FLT1 20 0.68 9.73 0.44
141 INT247568 Negative_regulation of Negative_regulation of VEGFA 5 0.41 5.35 0.43
142 INT96909 Regulation of Angpt1 2 0.17 0.37 0.43
143 INT268877 Regulation of Gene_expression of Vegfa 2 0.58 4.73 0.42
144 INT152023 Regulation of Vegfa 4 0.52 3.99 0.41
145 INT43720 Regulation of Positive_regulation of Vegfa 1 0.03 0.41 0.41
146 INT43722 Positive_regulation of Regulation of Vegfa 1 0.06 0.41 0.41
147 INT176085 Regulation of Tek 6 0.37 3.36 0.4
148 INT96870 Transcription of ARNT 1 0.44 0.81 0.4
149 INT255662 Regulation of Positive_regulation of Flt1 1 0.29 2.57 0.4
150 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39
151 INT129849 Positive_regulation of Localization of Vegfa 1 0.46 0.35 0.39
152 INT91975 Regulation of Binding of IL1B 2 0.14 0.66 0.38
153 INT247549 Transcription of Hif1a 7 0.42 8.77 0.36
154 INT176079 Positive_regulation of Tek 6 0.41 3.15 0.36
155 INT172798 Gene_expression of Vegfb 4 0.41 4.64 0.35
156 INT320784 Protein_catabolism of Hif1a 3 0.61 2.41 0.34
157 INT209937 Negative_regulation of Protein_catabolism of IL1B 2 0.24 1.15 0.32
158 INT247563 Negative_regulation of Positive_regulation of Hif1a 1 0.16 9.12 0.32
159 INT173105 Transcription of HIF1A 6 0.67 4.47 0.28
160 INT172788 Positive_regulation of Gene_expression of Vegfb 1 0.01 3.54 0.28
161 INT200550 Regulation of Flt1 7 0.45 5.22 0.27
162 INT232786 Positive_regulation of Localization of Hif1a 2 0.31 2.63 0.27
163 INT224619 Regulation of Positive_regulation of Vegfa 1 0.05 0.57 0.27
164 INT224638 Positive_regulation of Positive_regulation of Vegfa 1 0.06 0.57 0.27
165 INT212762 Regulation of FLT1 21 0.58 2.95 0.26
166 INT148796 Regulation of Phosphorylation of VEGFA 3 0.35 1.66 0.26
167 INT109537 Transcription of Vegfa 2 0.44 1.32 0.26
168 INT236397 Binding of Flt1 5 0.33 1.91 0.24
169 INT96908 Protein_catabolism of Angpt1 1 0.41 0.26 0.24
170 INT137608 Regulation of Localization of Vegfa 1 0.25 0.56 0.24
171 INT220396 Negative_regulation of Angpt1 4 0.26 1.64 0.23
172 INT96872 Positive_regulation of ARNT 2 0.32 1.82 0.23
173 INT139053 Phosphorylation of PRKCB 1 0.04 0.32 0.23
174 INT139051 Positive_regulation of Phosphorylation of PRKCB 1 0.02 0.33 0.23
175 INT96878 Positive_regulation of Gene_expression of ARNT 1 0.32 0.44 0.23
176 INT96880 Positive_regulation of Transcription of ARNT 1 0.30 0.44 0.23
177 INT139054 Negative_regulation of Phosphorylation of PRKCB 1 0.02 0.33 0.23
178 INT155532 Regulation of Regulation of IL1B 2 0.26 0.32 0.22
179 INT173103 Positive_regulation of Transcription of HIF1A 3 0.49 2.11 0.21
180 INT142121 Positive_regulation of Gene_expression of Bmp4 3 0.47 7 0.21
181 INT254040 Regulation of FGF9 2 0.57 1.04 0.21
182 INT206159 Negative_regulation of Regulation of VEGFA 3 0.24 2.38 0.2
183 INT247564 Positive_regulation of Transcription of Hif1a 1 0.19 2.05 0.2
184 INT324639 Transcription of Flt1 5 0.45 2.67 0.19
185 INT178481 Binding of Tek 2 0.28 1.55 0.19
186 INT144005 Negative_regulation of PRKCB 2 0.28 0.2 0.19
187 INT218284 Gene_expression of Grb10 15 0.72 1.85 0.18
188 INT283243 Negative_regulation of Vegfb 4 0.30 0.65 0.18
189 INT96874 Regulation of Transcription of ARNT 1 0.29 0.38 0.18
190 INT176091 Regulation of Positive_regulation of Tek 1 0.37 0.22 0.18
191 INT24818 Positive_regulation of Binding of VTN 1 0.49 0 0.18
192 INT139662 Gene_expression of FGF9 7 0.65 2.26 0.17
193 INT120085 Negative_regulation of Gene_expression of Bmp4 5 0.55 0.61 0.17
194 INT158015 Regulation of Gene_expression of FLT1 10 0.52 1.66 0.16
195 INT204721 Localization of FLT1 30 0.73 4.64 0.15
196 INT105044 Negative_regulation of Flt1 4 0.39 2.99 0.15
197 INT236400 Regulation of Flt1 3 0.25 1.84 0.14
198 INT249919 Regulation of Regulation of Hif1a 2 0.29 1.81 0.14
199 INT298697 Negative_regulation of Tek 2 0.35 0.85 0.14
200 INT249908 Binding of Hif1a 2 0.31 1.48 0.14
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