GO:0030955

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Name potassium ion binding
Categary Function
Go Slim No
Go Link GO:0030955
Unique Molecular Interactions 32
Total Molecular Interactions 37
Total Single Events 313
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for potassium ion binding. They are ordered first by their pain relevance and then by number of times they were reported for potassium ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
2 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
3 INT80793 Prkcg Regulation of Pkm2 1 0.29 0.2 0.83
4 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78
5 INT306258 HDAC4 Negative_regulation of Gene_expression of TNF 1 0.09 0.89 0.78
6 INT180496 Binding of CTS and PDXK 1 0.04 0.69 0.77
7 INT191355 HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
8 INT191354 Negative_regulation of HDAC4 Positive_regulation of Gene_expression of Shc1 1 0.02 1.07 0.16
9 INT347638 Negative_regulation of Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
10 INT151393 Binding of Kcna4 and Kcnip4 1 0.00 0.09 0.14
11 INT347639 Binding of Atp9a and Hdac4 1 0.01 0.97 0.14
12 INT138195 Binding of HDAC4 and Creb1 1 0.03 0.17 0.13
13 INT151394 Binding of Kcna4 and ISYNA1 1 0.00 0.08 0.11
14 INT190246 TARBP2 Positive_regulation of PKLR 1 0.01 0.41 0.1
15 INT145622 Binding of PKLR and UGT1A3 1 0.01 0 0.06
16 INT145623 Binding of PKLR and UGT2B4 1 0.02 0 0.06
17 INT145626 Binding of PKLR and UGT1A1 1 0.02 0 0.06
18 INT145621 Binding of PKLR and UGT2B7 1 0.02 0 0.06
19 INT145624 Binding of PKLR and UGT1A9 1 0.02 0 0.06
20 INT145625 Binding of PKLR and UGT2B17 1 0.01 0 0.06
21 INT292816 Binding of KCNJ11 and FTO 1 0.46 0.49 0.05
22 INT190247 TARBP2 Negative_regulation of PKLR 1 0.01 0.2 0.05
23 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03
24 INT272597 Binding of Dlg4 and Kcna4 1 0.17 0 0.03
25 INT290910 Pkm2 Negative_regulation of Shh 1 0.07 0.06 0
26 INT200647 HDAC4 Positive_regulation of CASP9 1 0.10 0.93 0
27 INT290911 Gene_expression of Shh Positive_regulation of Pkm2 1 0.07 0 0
28 INT277610 Binding of Runx2 and Hdac4 1 0.32 0.78 0
29 INT200650 HDAC4 Regulation of Gene_expression of AKT1 1 0.16 0.66 0
30 INT246649 Binding of Kcnj11 and Krt23 1 0.01 0.53 0
31 INT200644 HDAC4 Positive_regulation of CASP8 1 0.07 0.92 0
32 INT277611 Binding of Mef2c and Hdac4 1 0.34 1.12 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for potassium ion binding. They are ordered first by their pain relevance and then by number of times they were reported in potassium ion binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT130272 Gene_expression of Kcna4 12 0.75 9.25 7.61
2 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42
3 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39
4 INT91647 Gene_expression of PDXK 2 0.49 7.71 2.82
5 INT144840 Negative_regulation of Gene_expression of Kcna4 2 0.55 3.13 2.6
6 INT146458 Negative_regulation of Kcna4 3 0.40 3.44 2.42
7 INT144841 Regulation of Gene_expression of Kcna4 1 0.60 2.99 2.26
8 INT277591 Gene_expression of Hdac4 22 0.77 7.77 1.79
9 INT277581 Positive_regulation of Hdac4 4 0.50 1.47 1.25
10 INT168944 Transcription of Kcna4 1 0.44 2.22 1.25
11 INT188533 Regulation of PDXK 1 0.05 2.92 1.23
12 INT131900 Binding of Kcna4 3 0.37 0.32 1.15
13 INT60286 Gene_expression of PKLR 5 0.65 2.14 1.04
14 INT234473 Gene_expression of HDAC4 8 0.18 6.28 0.99
15 INT120408 Localization of PKLR 1 0.01 0.8 0.99
16 INT188543 Negative_regulation of Gene_expression of PDXK 1 0.04 1.51 0.73
17 INT157073 Positive_regulation of PKLR 6 0.36 5.48 0.69
18 INT188538 Regulation of Gene_expression of PDXK 1 0.05 1.85 0.69
19 INT39059 Binding of PDXK 2 0.31 1.37 0.65
20 INT168943 Negative_regulation of Transcription of Kcna4 1 0.35 1.12 0.63
21 INT60289 Negative_regulation of PKLR 5 0.21 1.75 0.53
22 INT120399 Positive_regulation of Phosphorylation of PKLR 1 0.01 0.44 0.53
23 INT120389 Phosphorylation of PKLR 2 0.11 1.81 0.51
24 INT333910 Positive_regulation of Gene_expression of HDAC4 2 0.07 1.5 0.49
25 INT179685 Positive_regulation of HDAC4 3 0.24 4.09 0.48
26 INT188532 Positive_regulation of PDXK 1 0.05 1.28 0.46
27 INT188537 Localization of PDXK 1 0.07 0.8 0.43
28 INT188542 Regulation of Positive_regulation of PDXK 1 0.05 1.07 0.42
29 INT188535 Protein_catabolism of PDXK 1 0.09 0.82 0.41
30 INT127413 Regulation of Kcna4 2 0.38 0.49 0.39
31 INT277579 Binding of Hdac4 1 0.37 3.84 0.38
32 INT277604 Negative_regulation of Hdac4 4 0.51 2.89 0.36
33 INT127412 Localization of Kcna4 2 0.78 0.49 0.36
34 INT277598 Regulation of Gene_expression of Hdac4 1 0.45 0.91 0.36
35 INT60287 Regulation of PKLR 1 0.15 0.32 0.35
36 INT221224 Gene_expression of KCNJ11 2 0.61 5.83 0.33
37 INT60288 Regulation of Gene_expression of PKLR 1 0.15 0.32 0.28
38 INT124568 Regulation of HDAC4 5 0.24 3.03 0.27
39 INT188541 Positive_regulation of Binding of PDXK 1 0.05 0.79 0.23
40 INT125877 Binding of PKLR 2 0.04 0.26 0.22
41 INT277584 Negative_regulation of Gene_expression of Hdac4 1 0.43 0.85 0.21
42 INT277594 Positive_regulation of Localization of Hdac4 1 0.50 1.71 0.21
43 INT277593 Localization of Hdac4 1 0.75 2.07 0.2
44 INT277600 Positive_regulation of Gene_expression of Hdac4 1 0.60 0.48 0.2
45 INT191155 Binding of HDAC4 5 0.08 2.79 0.17
46 INT277601 Positive_regulation of Positive_regulation of Hdac4 1 0.50 0.18 0.16
47 INT277582 Regulation of Hdac4 1 0.45 0.36 0.14
48 INT151392 Regulation of Binding of Kcna4 1 0.35 0.09 0.14
49 INT250219 Positive_regulation of KCNJ11 3 0.68 2.5 0.12
50 INT234460 Negative_regulation of Gene_expression of HDAC4 2 0.04 1.55 0.11
51 INT234465 Regulation of Negative_regulation of HDAC4 1 0.04 0.74 0.11
52 INT188539 Positive_regulation of Negative_regulation of PDXK 1 0.05 0.63 0.11
53 INT58644 Negative_regulation of KCNJ11 1 0.24 0 0.08
54 INT207818 Positive_regulation of Kcnj11 2 0.48 1.67 0.07
55 INT188536 Negative_regulation of Binding of PDXK 1 0.04 0.42 0.07
56 INT277599 Phosphorylation of Hdac4 1 0.82 3.24 0.05
57 INT188540 Negative_regulation of Positive_regulation of PDXK 1 0.04 0.27 0.05
58 INT290912 Positive_regulation of Pkm2 1 0.10 0.14 0.04
59 INT259662 Positive_regulation of Regulation of HDAC4 1 0.03 0.77 0.03
60 INT290924 Negative_regulation of Gene_expression of Pkm2 1 0.06 0.08 0.03
61 INT207834 Negative_regulation of Localization of KCNJ11 1 0.41 0 0.03
62 INT290921 Gene_expression of Pkm2 1 0.10 0.08 0.03
63 INT207832 Localization of KCNJ11 1 0.73 0 0.03
64 INT332926 Localization of HDAC4 1 0.10 0.11 0.03
65 INT272583 Gene_expression of Kcna4 1 0.28 0 0.03
66 INT82996 Transcription of PKLR 2 0.51 0.6 0
67 INT200682 Phosphorylation of HDAC4 2 0.44 1.24 0
68 INT188534 Positive_regulation of Gene_expression of PDXK 1 0.05 0.06 0
69 INT329212 Phosphorylation of KCNJ11 1 0.80 1.07 0
70 INT277580 Regulation of Localization of Hdac4 1 0.39 0 0
71 INT330341 Positive_regulation of Gene_expression of PKLR 1 0.08 1.13 0
72 INT200668 Regulation of Phosphorylation of HDAC4 1 0.24 0.71 0
73 INT290919 Regulation of Pkm2 1 0.04 0 0
74 INT277577 Transcription of Hdac4 1 0.69 0 0
75 INT319097 Negative_regulation of Transcription of PKLR 1 0.05 0.24 0
76 INT339052 Binding of KCNJ11 1 0.34 1.16 0
77 INT319098 Protein_catabolism of PKLR 1 0.13 0.49 0
78 INT239368 Negative_regulation of Binding of HDAC4 1 0.06 1.44 0
79 INT329213 Positive_regulation of Phosphorylation of KCNJ11 1 0.45 1.14 0
80 INT338233 Regulation of Gene_expression of HDAC4 1 0.03 0.18 0
81 INT290925 Negative_regulation of Pkm2 1 0.06 0 0
82 INT277603 Negative_regulation of Phosphorylation of Hdac4 1 0.43 0.39 0
83 INT330349 Negative_regulation of Gene_expression of PKLR 1 0.07 1.23 0
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