GO:0031045

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Name dense core granule
Categary Component
Go Slim No
Go Link GO:0031045
Unique Molecular Interactions 23
Total Molecular Interactions 28
Total Single Events 335
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for dense core granule. They are ordered first by their pain relevance and then by number of times they were reported for dense core granule. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT334833 Binding of Drd2 and Ncs1 1 0.05 1.11 0.76
2 INT117806 Binding of TRPV1 and Syt9 1 0.11 0.37 0.7
3 INT326586 SLC18A2 Negative_regulation of DDC 1 0.28 0.91 0.66
4 INT171825 Binding of Prkcg and Ncs1 1 0.00 0.07 0.66
5 INT171824 Binding of Ncs1 and Aspm 1 0.00 0.07 0.65
6 INT334835 Negative_regulation of Binding of Drd2 and Ncs1 1 0.04 0.56 0.38
7 INT334836 Ncs1 Regulation of Drd2 1 0.02 0.48 0.33
8 INT194977 Binding of Alox5 and Syt1 1 0.04 0.65 0.27
9 INT303058 Akt1 Negative_regulation of Gene_expression of Syt1 1 0.21 0.43 0.18
10 INT214953 Syt1 Regulation of Rims1 1 0.25 0 0.12
11 INT214955 Binding of Syt1 and Vamp2 1 0.22 0 0.1
12 INT214951 Binding of Syt1 and Vamp1 1 0.22 0 0.1
13 INT303055 Akt1 Negative_regulation of Syt1 1 0.21 0 0.07
14 INT278984 Binding of CFH and NCS1 1 0.02 0.63 0.05
15 INT303086 Binding of Mafk and Syt1 1 0.23 0.18 0.05
16 INT303057 Binding of Syn1 and Syt1 1 0.07 0.19 0.05
17 INT303059 Binding of Syt1 and Sdcbp 1 0.04 0.19 0.05
18 INT247080 Binding of CRH and CRHBP 1 0.11 0.2 0.03
19 INT303054 Rorb Positive_regulation of Gene_expression of Syt1 1 0.01 0 0.03
20 INT334837 Binding of Car2 and Ncs1 1 0.07 0 0.03
21 INT247085 Binding of CRHBP and GHRH 1 0.01 0.2 0.03
22 INT317128 Gene_expression of Ncs1 Negative_regulation of Csn 1 0.04 0.44 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for dense core granule. They are ordered first by their pain relevance and then by number of times they were reported in dense core granule. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT141751 Localization of Syt1 21 0.78 11.19 5.98
2 INT141750 Positive_regulation of Localization of Syt1 10 0.67 5.53 5.28
3 INT96504 Negative_regulation of SLC18A2 5 0.36 2.07 4.62
4 INT106274 Positive_regulation of Syt1 16 0.67 9.76 4.1
5 INT22578 Gene_expression of Syt1 43 0.77 11.02 3.66
6 INT151268 Phosphorylation of Syt1 4 0.61 1.65 2.95
7 INT141752 Negative_regulation of Localization of Syt1 5 0.42 4.96 2.68
8 INT234111 Gene_expression of NCS1 3 0.74 15.23 2.68
9 INT317124 Positive_regulation of Gene_expression of Ncs1 1 0.69 10.64 2.66
10 INT317117 Gene_expression of Ncs1 1 0.77 13.85 2.58
11 INT118701 Positive_regulation of Ncs1 2 0.69 4.13 2.03
12 INT151272 Positive_regulation of Phosphorylation of Syt1 2 0.45 0.32 1.93
13 INT106273 Positive_regulation of Positive_regulation of Syt1 2 0.29 1.22 1.42
14 INT171147 Binding of Syt1 7 0.35 6.11 1.36
15 INT244284 Binding of SLC18A2 1 0.23 1.87 1.34
16 INT132574 Positive_regulation of SLC18A2 1 0.12 0.25 0.99
17 INT326601 Gene_expression of SLC18A2 2 0.42 1.31 0.92
18 INT32418 Binding of NCS1 10 0.40 8.93 0.81
19 INT251448 Gene_expression of Ncs1 2 0.45 1.13 0.71
20 INT326602 Negative_regulation of Gene_expression of SLC18A2 1 0.25 0.93 0.67
21 INT22577 Positive_regulation of Gene_expression of Syt1 6 0.50 1.49 0.65
22 INT334828 Positive_regulation of Gene_expression of Ncs1 1 0.40 1.04 0.65
23 INT327659 Regulation of Syt1 1 0.20 0 0.56
24 INT118702 Regulation of Ncs1 2 0.53 1.59 0.47
25 INT278990 Negative_regulation of NCS1 1 0.36 1.82 0.46
26 INT5390 Binding of Ncs1 4 0.36 2.79 0.45
27 INT305077 Localization of CRHBP 1 0.76 0.28 0.44
28 INT146045 Regulation of Gene_expression of Syt1 4 0.21 0.84 0.4
29 INT98454 Positive_regulation of Ncs1 2 0.40 0.64 0.4
30 INT106271 Negative_regulation of Positive_regulation of Syt1 1 0.25 0.34 0.3
31 INT32417 Localization of NCS1 2 0.63 1.94 0.29
32 INT247097 Binding of CRHBP 3 0.34 0.4 0.28
33 INT354299 Positive_regulation of Syt1 1 0.67 0.1 0.27
34 INT160928 Negative_regulation of Syt1 4 0.57 1.9 0.25
35 INT221896 Protein_catabolism of Syt1 2 0.22 0.36 0.2
36 INT317123 Localization of Ncs1 1 0.75 0.16 0.2
37 INT278988 Regulation of Binding of NCS1 1 0.38 0.58 0.19
38 INT334823 Regulation of Ncs1 1 0.26 0.43 0.18
39 INT283534 Negative_regulation of Ncs1 2 0.25 0.79 0.17
40 INT278987 Positive_regulation of Gene_expression of NCS1 1 0.39 0.65 0.16
41 INT317120 Binding of Ncs1 1 0.37 0.06 0.11
42 INT351388 Positive_regulation of Binding of Syt1 1 0.11 0.33 0.1
43 INT303069 Transcription of Syt1 1 0.41 0 0.09
44 INT317121 Positive_regulation of Positive_regulation of Ncs1 1 0.46 0.06 0.09
45 INT317122 Regulation of Positive_regulation of Ncs1 1 0.45 0.13 0.09
46 INT278991 Regulation of Gene_expression of NCS1 1 0.38 1.58 0.09
47 INT32538 Localization of Ncs1 1 0.80 0.99 0.08
48 INT190861 Binding of Syt1 1 0.03 0.55 0.08
49 INT261368 Negative_regulation of Ncs1 1 0.03 1.33 0.07
50 INT278986 Phosphorylation of NCS1 1 0.68 0.46 0.06
51 INT351387 Regulation of Syt1 1 0.11 0.32 0.05
52 INT278989 Regulation of NCS1 1 0.38 1.59 0.04
53 INT171149 Negative_regulation of Gene_expression of Syt1 2 0.45 0.22 0
54 INT317118 Negative_regulation of Gene_expression of Ncs1 1 0.42 0.29 0
55 INT325422 Protein_catabolism of Ncs1 1 0.02 0.99 0
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