GO:0031047

From wiki-pain
Jump to: navigation, search
Name gene silencing by RNA
Categary Process
Go Slim No
Go Link GO:0031047
Unique Molecular Interactions 42
Total Molecular Interactions 59
Total Single Events 227
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for gene silencing by RNA. They are ordered first by their pain relevance and then by number of times they were reported for gene silencing by RNA. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT117535 SND1 Positive_regulation of Gene_expression of TNF 1 0.06 0.29 0.71
2 INT117534 TNF Positive_regulation of Positive_regulation of SND1 1 0.06 0.29 0.7
3 INT150205 Tnrc6a Negative_regulation of PTGS2 1 0.00 0.42 0.49
4 INT330519 Binding of CD8A and DICER1 1 0.08 0.99 0.38
5 INT272363 Binding of Adar and Adarb1 3 0.26 0.76 0.36
6 INT114967 ERI1 Negative_regulation of CPOX 1 0.00 0.25 0.14
7 INT303128 Tnrc6a Regulation of Gene_expression of Nos2 1 0.00 0.57 0.14
8 INT350711 Ifnb1 Negative_regulation of Gene_expression of DICER1 1 0.03 0.15 0.14
9 INT190246 TARBP2 Positive_regulation of PKLR 1 0.01 0.41 0.1
10 INT204993 Eri1 Positive_regulation of Gene_expression of Pink1 1 0.22 0.61 0.08
11 INT322560 Binding of TNFSF10 and DICER1 1 0.07 1.76 0.07
12 INT204998 Hmmr Positive_regulation of Eri1 1 0.00 0.58 0.06
13 INT172349 Eri1 Regulation of Gene_expression of Agrp 1 0.03 0.28 0.05
14 INT172348 Eri1 Negative_regulation of Gene_expression of Agrp 1 0.07 0.28 0.05
15 INT190247 TARBP2 Negative_regulation of PKLR 1 0.01 0.2 0.05
16 INT315263 Eri1 Regulation of Rela 1 0.00 0.49 0
17 INT315271 Eri1 Regulation of Nfe2l2 1 0.00 0.48 0
18 INT172347 Eri1 Negative_regulation of Hras1 1 0.00 0.76 0
19 INT315265 Eri1 Negative_regulation of Keap1 1 0.01 0.26 0
20 INT315260 Eri1 Regulation of Keap1 1 0.00 0.48 0
21 INT225644 Binding of TARBP2 and Acp5 1 0.04 0.15 0
22 INT225613 TARBP2 Positive_regulation of Prkdc 1 0.00 0 0
23 INT205000 Binding of Xpo5 and Pol 1 0.01 0.27 0
24 INT225621 Positive_regulation of Binding of TARBP2 and Esr1 1 0.03 0 0
25 INT315073 DROSHA Regulation of PAR4 1 0.36 0.13 0
26 INT225626 Binding of TARBP2 and Esr1 1 0.02 0 0
27 INT185353 Eri1 Negative_regulation of Transcription of Egfr 1 0.01 0.5 0
28 INT225643 Binding of TARBP2 and Acsl1 1 0.00 0 0
29 INT315059 PAR4 Regulation of DROSHA 1 0.19 0.52 0
30 INT225619 Binding of TARBP2 and Ep300 1 0.02 0 0
31 INT272364 Gene_expression of Adar Negative_regulation of Adarb1 1 0.31 0.17 0
32 INT172345 Eri1 Negative_regulation of Gene_expression of Hras1 1 0.00 0.76 0
33 INT272524 DICER1 Negative_regulation of Dmpk 1 0.04 0.07 0
34 INT352841 Binding of Miox and Lin28a 1 0.00 0 0
35 INT281718 Binding of Adar and Adarb2 1 0.11 0.21 0
36 INT172344 Eri1 Negative_regulation of Positive_regulation of Hras1 1 0.00 0.76 0
37 INT225634 Binding of TARBP2 and MED23 1 0.04 0.15 0
38 INT351761 Adar Negative_regulation of Gene_expression of Adarb1 1 0.27 0.8 0
39 INT352842 Binding of Lin28a and Mirlet7a-1 1 0.03 0 0
40 INT225618 TARBP2 Positive_regulation of gr 1 0.01 0 0
41 INT341628 Binding of ADAR and PROC 1 0.03 5.01 0
42 INT185357 Eri1 Negative_regulation of Gene_expression of Egfr 1 0.01 0.57 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for gene silencing by RNA. They are ordered first by their pain relevance and then by number of times they were reported in gene silencing by RNA. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT190280 Gene_expression of DICER1 12 0.65 9.54 2.67
2 INT76008 Positive_regulation of ADAR 7 0.60 2.24 2
3 INT139402 Negative_regulation of Tnrc6a 1 0.00 2.22 1.8
4 INT330526 Positive_regulation of Gene_expression of DICER1 5 0.30 3.34 1.18
5 INT272351 Regulation of Adar 5 0.50 1.56 0.99
6 INT126102 Binding of Tnrc6a 1 0.00 1.03 0.96
7 INT313713 Positive_regulation of Regulation of Adar 1 0.41 0 0.84
8 INT117547 Gene_expression of SND1 2 0.57 1.27 0.71
9 INT272360 Gene_expression of Adar 13 0.61 4.33 0.69
10 INT117542 Positive_regulation of SND1 2 0.34 2.19 0.69
11 INT62300 Regulation of SND1 1 0.47 1.07 0.48
12 INT29058 Localization of ADAR 2 0.75 3.88 0.46
13 INT169943 Gene_expression of Eri1 22 0.35 10.45 0.41
14 INT272502 Transcription of DICER1 3 0.08 2.14 0.39
15 INT343811 Positive_regulation of Transcription of DICER1 1 0.06 2.06 0.39
16 INT272348 Binding of Adar 8 0.38 1.01 0.36
17 INT343810 Binding of DICER1 1 0.05 1.88 0.35
18 INT330525 Positive_regulation of DICER1 2 0.17 1.34 0.34
19 INT272330 Positive_regulation of Adar 2 0.34 0.05 0.33
20 INT316448 Positive_regulation of Lin28a 1 0.26 0.53 0.24
21 INT350691 Localization of DICER1 1 0.08 1.18 0.23
22 INT131128 Gene_expression of ADAR 4 0.59 4.3 0.16
23 INT190110 Positive_regulation of Eri1 2 0.27 3.47 0.15
24 INT272354 Regulation of Gene_expression of Adar 1 0.49 0.31 0.14
25 INT303120 Regulation of Tnrc6a 1 0.00 0.28 0.14
26 INT350685 Negative_regulation of Gene_expression of DICER1 1 0.05 0.15 0.14
27 INT350676 Regulation of Gene_expression of DICER1 1 0.07 0.16 0.14
28 INT204967 Negative_regulation of Eri1 2 0.17 1.41 0.12
29 INT200071 Gene_expression of ERI1 2 0.65 0.41 0.12
30 INT200070 Negative_regulation of ERI1 1 0.11 0.24 0.12
31 INT169935 Positive_regulation of Gene_expression of Eri1 3 0.19 2.46 0.09
32 INT172342 Regulation of Eri1 2 0.03 0.3 0.08
33 INT303119 Positive_regulation of Tnrc6a 1 0.01 0.74 0.08
34 INT200069 Regulation of ERI1 1 0.05 0.15 0.08
35 INT272508 Regulation of DICER1 4 0.11 1.21 0.05
36 INT341630 Regulation of ADAR 1 0.24 0.4 0.05
37 INT272344 Transcription of Adar 4 0.57 1.85 0.04
38 INT190102 Protein_catabolism of Eri1 3 0.25 1.69 0.04
39 INT352834 Protein_catabolism of Adar 1 0.56 0.15 0.04
40 INT245960 Localization of DROSHA 4 0.61 0.41 0
41 INT217417 Binding of ERI1 2 0.36 0.99 0
42 INT272346 Regulation of Transcription of Adar 2 0.36 0.96 0
43 INT337457 Phosphorylation of ADAR 2 0.71 0.69 0
44 INT190271 Negative_regulation of DICER1 2 0.04 0.24 0
45 INT337479 Binding of ADAR 2 0.37 1.3 0
46 INT272335 Positive_regulation of Transcription of Adar 1 0.40 0 0
47 INT315125 Regulation of Gene_expression of DROSHA 1 0.44 0.74 0
48 INT315121 Regulation of DROSHA 1 0.32 3.15 0
49 INT204991 Positive_regulation of Positive_regulation of Eri1 1 0.19 0.96 0
50 INT351754 Negative_regulation of Gene_expression of Adar 1 0.39 1.78 0
51 INT315095 Positive_regulation of Gene_expression of DROSHA 1 0.56 1.58 0
52 INT272359 Positive_regulation of Gene_expression of Adar 1 0.55 1.47 0
53 INT352833 Binding of Lin28a 1 0.19 0.54 0
54 INT337477 Positive_regulation of Phosphorylation of ADAR 1 0.06 0.28 0
55 INT283730 Binding of Eri1 1 0.01 0.26 0
56 INT351753 Negative_regulation of Transcription of Adar 1 0.28 0.91 0
57 INT219055 Regulation of Gene_expression of Eri1 1 0.00 0.1 0
58 INT131129 Negative_regulation of ADAR 1 0.58 0 0
59 INT272337 Positive_regulation of Binding of Adar 1 0.40 0 0
60 INT337463 Negative_regulation of Positive_regulation of ADAR 1 0.07 0.26 0
61 INT202209 Localization of Xpo5 1 0.40 0.18 0
62 INT315106 Gene_expression of DROSHA 1 0.63 3.24 0
63 INT225465 Transcription of TARBP2 1 0.08 0.13 0
64 INT337468 Positive_regulation of Binding of ADAR 1 0.08 0 0
65 INT272336 Localization of Adar 1 0.63 0.12 0
66 INT315129 Negative_regulation of DROSHA 1 0.31 2.01 0
67 INT352844 Protein_catabolism of DICER1 1 0.12 0 0
68 INT225458 Phosphorylation of TARBP2 1 0.09 0 0
69 INT337668 Positive_regulation of Gene_expression of SND1 1 0.51 0.99 0
70 INT225459 Binding of TARBP2 1 0.05 0 0
71 INT225461 Negative_regulation of TARBP2 1 0.06 0 0
72 INT272361 Negative_regulation of Adar 1 0.40 0.37 0
73 INT204984 Transcription of Eri1 1 0.21 0.78 0
74 INT315131 Negative_regulation of Gene_expression of DROSHA 1 0.30 0.29 0
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox