GO:0031092

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Name platelet alpha granule membrane
Categary Component
Go Slim No
Go Link GO:0031092
Unique Molecular Interactions 116
Total Molecular Interactions 165
Total Single Events 2017
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for platelet alpha granule membrane. They are ordered first by their pain relevance and then by number of times they were reported for platelet alpha granule membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT209853 TNF Regulation of Gene_expression of CD36 1 0.61 3.41 1.59
3 INT101317 Binding of Selplg and Selp 1 0.02 3.72 1.01
4 INT209852 TNF Negative_regulation of Gene_expression of CD36 1 0.43 0.61 0.98
5 INT182814 Binding of ICAM1 and PECAM1 2 0.02 3.32 0.77
6 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75
7 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75
8 INT209854 IL4 Positive_regulation of Gene_expression of CD36 1 0.51 1.2 0.65
9 INT121713 WAS Positive_regulation of Gene_expression of SELP 1 0.30 0.49 0.63
10 INT182819 Binding of CD63 and PECAM1 1 0.00 1.63 0.61
11 INT77508 ST13 Negative_regulation of Gene_expression of CD9 1 0.09 0.5 0.54
12 INT187101 Selp Regulation of Sele 1 0.20 1.23 0.53
13 INT96103 Binding of PPBP and Selp 1 0.00 1.22 0.46
14 INT96083 Binding of PPBP and SELP 1 0.02 1.21 0.46
15 INT96095 Binding of Selp and Pf4 1 0.01 1.2 0.45
16 INT96097 Binding of SELP and Pf4 1 0.13 1.2 0.45
17 INT343853 IRF6 Positive_regulation of PECAM1 1 0.00 0.53 0.43
18 INT209858 TNF Regulation of Transcription of CD36 1 0.27 0 0.4
19 INT51829 Binding of ITGA2B and ANGPTL5 1 0.35 1.08 0.4
20 INT216709 Binding of SELP and PSMG1 3 0.08 1.48 0.37
21 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37
22 INT99015 Binding of Selp and Vcam1 2 0.27 1.76 0.35
23 INT114809 Selp Positive_regulation of Gene_expression of F3 1 0.00 0.88 0.34
24 INT139974 Adp Positive_regulation of Gene_expression of Selp 1 0.00 1.79 0.34
25 INT322045 Gp6 Positive_regulation of Gene_expression of Selp 1 0.04 0.15 0.33
26 INT209855 NFE2L2 Positive_regulation of Gene_expression of CD36 1 0.27 0.72 0.32
27 INT334024 Ccl25 Positive_regulation of Gene_expression of CD36 1 0.31 0.36 0.31
28 INT96096 Binding of Serpinc1 and Selp 1 0.00 0.69 0.3
29 INT96102 Binding of TAT and Selp 1 0.04 0.7 0.3
30 INT140474 Tnfrsf1a Positive_regulation of PECAM1 1 0.00 1.18 0.3
31 INT96082 Binding of SELP and TAT 1 0.40 0.69 0.3
32 INT96100 Binding of SELP and F2 1 0.01 0.67 0.29
33 INT96101 Binding of SELP and Serpinc1 1 0.01 0.69 0.29
34 INT96094 Binding of Selp and F2 1 0.00 0.67 0.29
35 INT334023 pma Positive_regulation of Gene_expression of CD36 1 0.04 0.31 0.28
36 INT128644 Binding of Icam1 and Selp 2 0.39 0.57 0.25
37 INT76224 Ptgs1 Regulation of Gene_expression of PECAM1 1 0.00 0.25 0.25
38 INT209849 TNF Positive_regulation of Gene_expression of CD36 1 0.69 0.18 0.25
39 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24
40 INT63420 F2 Positive_regulation of Gene_expression of ITGA2B 1 0.14 0.45 0.23
41 INT63421 F2 Positive_regulation of Gene_expression of SELP 1 0.09 0.45 0.23
42 INT209856 IL1A Negative_regulation of Transcription of CD36 1 0.26 0.1 0.22
43 INT209848 TNF Positive_regulation of CD36 1 0.46 0.24 0.22
44 INT209851 TGFB2 Negative_regulation of Gene_expression of CD36 1 0.16 0.16 0.21
45 INT209857 IL10 Negative_regulation of Gene_expression of CD36 1 0.31 0.16 0.2
46 INT51830 Positive_regulation of Binding of ITGA2B and ANGPTL5 1 0.51 0.57 0.2
47 INT51828 Negative_regulation of Binding of ITGA2B and ANGPTL5 1 0.31 0.51 0.2
48 INT93648 Adp Positive_regulation of ITGA2B 1 0.00 0.79 0.2
49 INT338898 Binding of PECAM1 and PTPN11 1 0.04 0.38 0.19
50 INT99010 Selp Regulation of Vcam1 1 0.20 1.35 0.18
51 INT99014 Binding of Sell and Selp 1 0.13 1.35 0.18
52 INT99008 Regulation of Binding of Selp and Vcam1 1 0.33 1.36 0.18
53 INT99009 Regulation of Binding of Sell and Selp 1 0.15 1.36 0.18
54 INT336751 Binding of Selp and Cd40 1 0.03 2.49 0.18
55 INT99013 Binding of Itgb2 and Selp 1 0.16 1.36 0.18
56 INT99006 Regulation of Binding of Selp and Itga1 1 0.06 1.36 0.18
57 INT99012 Binding of Selp and Itga1 1 0.05 1.36 0.18
58 INT99011 Regulation of Binding of Itgb2 and Selp 1 0.19 1.37 0.18
59 INT281307 Binding of Selp and Selplg 1 0.01 0.76 0.17
60 INT101318 Negative_regulation of Binding of tf and Selp 1 0.01 0.77 0.17
61 INT101316 Binding of tf and Selp 1 0.01 0.77 0.17
62 INT267138 Binding of CDH5 and PECAM1 2 0.16 2.69 0.16
63 INT171945 PECAM1 Positive_regulation of Gene_expression of ICAM1 1 0.06 1.66 0.16
64 INT141759 Nfkb1 Regulation of PECAM1 1 0.01 1.18 0.16
65 INT171544 PECAM1 Positive_regulation of ICAM1 1 0.01 0.47 0.16
66 INT171944 ICAM1 Positive_regulation of Gene_expression of PECAM1 1 0.06 1.66 0.16
67 INT141762 Nfkb1 Regulation of Positive_regulation of PECAM1 1 0.01 1.21 0.16
68 INT273891 WDTC1 Positive_regulation of Gene_expression of SELP 1 0.00 0.45 0.15
69 INT10730 CD9 Regulation of CD4 1 0.42 1.3 0.12
70 INT10732 NEUROD1 Regulation of CD9 1 0.49 1.29 0.12
71 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11
72 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
73 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11
74 INT338901 Binding of PECAM1 and PTPN6 1 0.03 0.18 0.1
75 INT216707 Positive_regulation of Binding of SELP and PSMG1 1 0.10 0.36 0.09
76 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
77 INT216708 Binding of ITGA2B and SELP 1 0.35 0.36 0.09
78 INT216710 Positive_regulation of Binding of ITGA2B and SELP 1 0.48 0.36 0.09
79 INT171847 Binding of PECAM1 and VCAM1 1 0.01 1 0.06
80 INT156143 MLL Positive_regulation of PECAM1 1 0.00 0.47 0.06
81 INT334027 Ccl25 Regulation of Gene_expression of CD36 1 0.14 0.24 0.05
82 INT220458 Binding of VCAN and SELP 1 0.01 1.15 0.05
83 INT216712 Binding of ITGA2B and PSMG1 1 0.09 0.18 0.05
84 INT334026 pma Regulation of Gene_expression of CD36 1 0.02 0.16 0.05
85 INT216706 Positive_regulation of Binding of ITGA2B and PSMG1 1 0.12 0.18 0.05
86 INT311724 Plat Positive_regulation of Gene_expression of Selp 1 0.11 0.6 0.03
87 INT189546 Binding of CD9 and FN1 1 0.01 0.6 0
88 INT152135 TDRD7 Positive_regulation of Gene_expression of SELP 1 0.26 0 0
89 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0
90 INT162508 Binding of ITGA2B and ITPR1 1 0.02 0.05 0
91 INT170120 PECAM1 Regulation of ITGAM 1 0.00 1.07 0
92 INT170118 PECAM1 Regulation of CD44 1 0.01 1.07 0
93 INT170123 ITGAL Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0
94 INT283632 Binding of Selp and Ie 1 0.00 0.22 0
95 INT170125 ITGAM Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0
96 INT339702 TRO Positive_regulation of CD36 1 0.08 1.06 0
97 INT170126 PECAM1 Regulation of ITGB2 1 0.01 1.07 0
98 INT191801 Binding of SELP and CD24 1 0.12 0.67 0
99 INT170115 PECAM1 Regulation of ITGAL 1 0.00 1.07 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for platelet alpha granule membrane. They are ordered first by their pain relevance and then by number of times they were reported in platelet alpha granule membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03
2 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76
3 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23
4 INT49141 Gene_expression of Selp 157 0.78 85.22 24.78
5 INT142621 Positive_regulation of Gene_expression of CD36 38 0.70 15.18 13.4
6 INT71510 Positive_regulation of Selp 47 0.68 30.43 12.8
7 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64
8 INT209866 Regulation of Gene_expression of CD36 27 0.60 10.04 8.42
9 INT51458 Negative_regulation of Gene_expression of Selp 29 0.57 12.64 8.1
10 INT67424 Positive_regulation of Gene_expression of Selp 36 0.68 17.08 7.95
11 INT63169 Positive_regulation of Gene_expression of Selp 35 0.69 21.95 7.16
12 INT63170 Positive_regulation of Selp 27 0.68 24.1 6.3
13 INT63351 Negative_regulation of Gene_expression of PECAM1 19 0.52 16.06 5.73
14 INT164656 Negative_regulation of Gene_expression of CD36 24 0.57 6.51 5.39
15 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25
16 INT99001 Negative_regulation of Selp 23 0.59 16.68 4.74
17 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69
18 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66
19 INT61036 Negative_regulation of Selp 12 0.50 7.45 4.46
20 INT51898 Binding of PECAM1 26 0.36 18.87 4.22
21 INT117551 Regulation of Gene_expression of Selp 15 0.44 7.32 4.2
22 INT51831 Negative_regulation of ITGA2B 20 0.57 10.59 3.91
23 INT124655 Negative_regulation of PECAM1 13 0.23 10.32 3.78
24 INT52227 Gene_expression of CD9 11 0.75 6.23 3.71
25 INT67423 Regulation of Gene_expression of Selp 16 0.60 7.4 3.68
26 INT33739 Gene_expression of ITGA2B 25 0.75 8.19 3.6
27 INT73802 Regulation of Selp 17 0.60 8.72 3.51
28 INT26702 Transcription of CD36 17 0.70 3.56 3.49
29 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48
30 INT130557 Negative_regulation of Gene_expression of Selp 17 0.54 6.56 3.45
31 INT76501 Binding of Selp 16 0.41 8.51 3.4
32 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
33 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
34 INT59719 Localization of SELP 12 0.78 8.4 2.95
35 INT28891 Localization of Selp 13 0.60 8.23 2.83
36 INT156579 Localization of Selp 14 0.73 6.53 2.69
37 INT52228 Negative_regulation of Gene_expression of CD9 3 0.57 2.45 2.54
38 INT76713 Regulation of Gene_expression of PECAM1 16 0.40 14.52 2.51
39 INT198662 Positive_regulation of CD36 14 0.68 7.73 2.36
40 INT96084 Binding of Selp 12 0.48 8.41 2.16
41 INT26706 Positive_regulation of Transcription of CD36 8 0.68 3.32 2.12
42 INT94285 Negative_regulation of CD36 10 0.43 6.61 1.98
43 INT51896 Localization of PECAM1 11 0.47 9.8 1.78
44 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
45 INT100549 Negative_regulation of SELP 6 0.43 4.17 1.46
46 INT33133 Positive_regulation of ITGA2B 13 0.67 4.09 1.44
47 INT112562 Binding of SELP 11 0.34 6.25 1.44
48 INT28892 Positive_regulation of Localization of Selp 3 0.35 1.04 1.4
49 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
50 INT100548 Regulation of SELP 8 0.29 8.56 1.17
51 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
52 INT78050 Positive_regulation of Positive_regulation of Selp 3 0.43 3.63 1.02
53 INT63348 Regulation of PECAM1 14 0.40 16.05 0.97
54 INT83948 Transcription of PECAM1 2 0.09 2.97 0.87
55 INT98994 Regulation of Selp 10 0.45 3.91 0.83
56 INT115613 Regulation of Gene_expression of ITGA2B 3 0.44 1.43 0.8
57 INT27077 Binding of CD36 4 0.37 2.14 0.72
58 INT33733 Binding of ITGA2B 12 0.36 3.86 0.71
59 INT25134 Positive_regulation of CD9 3 0.49 3.38 0.66
60 INT187088 Regulation of Negative_regulation of Selp 1 0.31 1.07 0.61
61 INT145537 Regulation of Localization of PECAM1 3 0.18 4.86 0.59
62 INT157576 Positive_regulation of Localization of Selp 2 0.49 1.19 0.59
63 INT63423 Negative_regulation of Gene_expression of SELP 13 0.55 1.98 0.57
64 INT142620 Regulation of CD36 6 0.62 0.72 0.54
65 INT18506 Negative_regulation of CD9 4 0.57 3.79 0.52
66 INT33737 Negative_regulation of Binding of ITGA2B 3 0.41 0.29 0.44
67 INT136325 Negative_regulation of Binding of Selp 2 0.59 2.26 0.42
68 INT63424 Negative_regulation of Gene_expression of ITGA2B 2 0.57 0.9 0.42
69 INT267147 Regulation of Positive_regulation of SELP 2 0.29 3.94 0.42
70 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
71 INT63422 Positive_regulation of Gene_expression of ITGA2B 4 0.67 1.11 0.39
72 INT140465 Negative_regulation of Positive_regulation of PECAM1 2 0.01 2.11 0.39
73 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
74 INT267144 Positive_regulation of Localization of SELP 2 0.44 3.79 0.38
75 INT169628 Binding of SNCA 4 0.47 3.53 0.36
76 INT91820 Regulation of ITGA2B 3 0.44 2.03 0.32
77 INT10801 Localization of CD36 3 0.73 2.12 0.32
78 INT267141 Regulation of Binding of PECAM1 2 0.18 3.2 0.32
79 INT209865 Negative_regulation of Transcription of CD36 1 0.57 0.15 0.32
80 INT174810 Phosphorylation of SELP 1 0.61 0.74 0.31
81 INT343973 Localization of SNCA 1 0.63 0.07 0.3
82 INT267142 Phosphorylation of PECAM1 2 0.61 2.35 0.27
83 INT267148 Positive_regulation of Phosphorylation of PECAM1 2 0.37 2.36 0.27
84 INT101313 Protein_catabolism of Selp 1 0.17 0.94 0.26
85 INT216732 Regulation of Localization of SELP 1 0.38 0 0.24
86 INT294737 Transcription of Selp 1 0.11 1.39 0.24
87 INT142052 Binding of Snca 4 0.47 1.02 0.22
88 INT108041 Negative_regulation of Phosphorylation of Selp 1 0.03 0.32 0.22
89 INT108042 Phosphorylation of Selp 1 0.05 0.32 0.22
90 INT222191 Regulation of Gene_expression of CD9 1 0.07 0.38 0.19
91 INT222201 Positive_regulation of Gene_expression of CD9 1 0.18 0.37 0.19
92 INT52998 Regulation of CD9 2 0.44 1.6 0.17
93 INT349473 Negative_regulation of Positive_regulation of Selp 1 0.17 0.38 0.17
94 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
95 INT141758 Positive_regulation of Positive_regulation of PECAM1 1 0.01 1.21 0.16
96 INT328709 Negative_regulation of Localization of Selp 1 0.01 0.76 0.16
97 INT80386 Positive_regulation of Negative_regulation of ITGA2B 1 0.49 0.2 0.16
98 INT157084 Localization of Snca 1 0.51 0.17 0.16
99 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
100 INT216725 Negative_regulation of Positive_regulation of ITGA2B 1 0.41 0 0.15
101 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
102 INT31433 Binding of CD9 1 0.36 1.36 0.13
103 INT285265 Regulation of Localization of Selp 1 0.07 0.42 0.13
104 INT271406 Positive_regulation of Binding of SELP 1 0.21 0.83 0.12
105 INT170260 Regulation of Gene_expression of SELP 3 0.21 2.67 0.11
106 INT209861 Regulation of Transcription of CD36 1 0.44 0 0.09
107 INT33742 Protein_catabolism of ITGA2B 1 0.51 0 0.07
108 INT200609 Regulation of Localization of Selp 1 0.20 0.64 0.07
109 INT294739 Negative_regulation of Transcription of Selp 1 0.07 0.18 0.06
110 INT178482 Regulation of Positive_regulation of Selp 1 0.04 1.38 0.05
111 INT142622 Positive_regulation of Regulation of CD36 2 0.47 0.14 0.03
112 INT33132 Positive_regulation of Positive_regulation of ITGA2B 2 0.49 0.3 0
113 INT339735 Regulation of Localization of CD36 1 0.22 0.09 0
114 INT173624 Negative_regulation of Positive_regulation of SELP 1 0.04 0.38 0
115 INT170139 Negative_regulation of Regulation of PECAM1 1 0.02 0.19 0
116 INT156580 Negative_regulation of Localization of Selp 1 0.06 0.13 0
117 INT349471 Regulation of Binding of Selp 1 0.18 0 0
118 INT112564 Positive_regulation of Binding of ITGA2B 1 0.07 0 0
119 INT339738 Positive_regulation of Localization of CD36 1 0.25 0.14 0
120 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
121 INT172188 Positive_regulation of Transcription of PECAM1 1 0.08 1.21 0
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