GO:0031093

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Name platelet alpha granule lumen
Categary Component
Go Slim No
Go Link GO:0031093
Unique Molecular Interactions 1518
Total Molecular Interactions 2213
Total Single Events 17115
Pain Genes Associated 43

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for platelet alpha granule lumen. They are ordered first by their pain relevance and then by number of times they were reported for platelet alpha granule lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT107331 Binding of PPBP and Adarb1 1 0.01 0 3.67
2 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
3 INT66157 Binding of ALB and BDP1 1 0.11 0 2.13
4 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91
5 INT166947 Ngf Positive_regulation of KNG1 1 0.00 0.47 1.86
6 INT224432 TNF Positive_regulation of Gene_expression of VEGFA 1 0.13 5.83 1.8
7 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
8 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
9 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
10 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
11 INT322412 PPBP Negative_regulation of Phosphorylation of Akt1 1 0.01 0 1.65
12 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
13 INT326509 Binding of ACE and VWF 1 0.05 2.07 1.59
14 INT266406 Binding of APP and Ager 1 0.00 2.34 1.57
15 INT66713 Binding of BDKRB1 and KNG1 2 0.22 0.39 1.53
16 INT61443 Binding of KNG1 and Tyr 1 0.00 0 1.46
17 INT151514 Olfr155 Negative_regulation of Gene_expression of VEGFA 1 0.00 1.8 1.42
18 INT225019 PDGFB Positive_regulation of Gene_expression of Cxcl1 1 0.27 0.54 1.4
19 INT56093 FGFR1 Regulation of Gene_expression of SERPINE1 1 0.23 1.71 1.37
20 INT126639 KNG1 Positive_regulation of Alox15 1 0.17 0.62 1.36
21 INT126640 Negative_regulation of KNG1 Positive_regulation of Alox15 1 0.14 0.62 1.36
22 INT351205 VEGFA Positive_regulation of Binding of MRGPRX1 1 0.08 0.65 1.35
23 INT178986 Binding of MMP9 and TIMP1 4 0.47 2.58 1.33
24 INT56087 TNF Regulation of Gene_expression of SERPINE1 1 0.43 1.67 1.33
25 INT121457 KNG1 Positive_regulation of Trpv1 1 0.16 0.91 1.33
26 INT39950 Binding of ALB and PDYN 1 0.31 0 1.32
27 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31
28 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
29 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
30 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
31 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
32 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
33 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
34 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
35 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
36 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
37 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
38 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
39 INT19535 Binding of ADRA1D and ALB 3 0.42 0.8 1.15
40 INT99691 Pdpk1 Positive_regulation of Positive_regulation of VEGFA 1 0.01 0.72 1.11
41 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1
42 INT136989 EGF Negative_regulation of Positive_regulation of KCNJ2 1 0.04 1.09 1.1
43 INT74939 IL1B Positive_regulation of Gene_expression of HGF 1 0.58 0.72 1.09
44 INT168529 APP Regulation of FSIP1 2 0.65 2.26 1.07
45 INT150794 ZNF398 Positive_regulation of Localization of THBS1 1 0.09 1.02 1.07
46 INT150789 THBS3 Negative_regulation of THBS1 1 0.18 1.01 1.06
47 INT150787 ZNF398 Positive_regulation of Gene_expression of SPARC 1 0.13 1.02 1.05
48 INT136988 EGF Negative_regulation of KCNJ2 1 0.04 1.09 1.04
49 INT106706 POMC Negative_regulation of Binding of FN1 1 0.19 0.79 1.02
50 INT54737 PPBP Regulation of NCOR2 1 0.01 0.15 1.01
51 INT73681 Regulation of KNG1 Positive_regulation of ALB 1 0.30 0.38 0.99
52 INT73680 KNG1 Positive_regulation of ALB 1 0.51 0.38 0.98
53 INT140653 IGF1 Negative_regulation of Protein_catabolism of PARP1 1 0.32 0.63 0.98
54 INT140652 IGF1 Positive_regulation of Phosphorylation of MAPK1 1 0.26 0.63 0.98
55 INT66712 Binding of BDKRB2 and KNG1 1 0.06 0.22 0.97
56 INT66711 Negative_regulation of Binding of BDKRB2 and KNG1 1 0.07 0.22 0.97
57 INT303690 KNG1 Positive_regulation of CPOX 1 0.01 0.76 0.96
58 INT66714 Negative_regulation of Binding of BDKRB1 and KNG1 1 0.13 0.22 0.96
59 INT161231 Positive_regulation of Htr1a Positive_regulation of Gene_expression of VEGFA 1 0.67 0.16 0.95
60 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
61 INT137922 VEGFA Positive_regulation of Oprm1 1 0.06 0 0.94
62 INT102554 HGF Positive_regulation of Phosphorylation of RPS6KA1 1 0.21 0.93 0.94
63 INT137923 VEGFA Positive_regulation of Phosphorylation of Akt1 1 0.05 0 0.93
64 INT222979 Negative_regulation of Binding of COL1A1 and FN1 1 0.01 1.64 0.93
65 INT137921 VEGFA Positive_regulation of Ephb2 1 0.03 0 0.93
66 INT222978 Binding of COL1A1 and FN1 1 0.01 1.64 0.92
67 INT118288 EGF Positive_regulation of Phosphorylation of EGFR 9 0.54 3.85 0.9
68 INT220744 EGF Positive_regulation of Gene_expression of KRT20 1 0.01 1.26 0.9
69 INT169477 TGFB3 Positive_regulation of Spink3 1 0.02 1.83 0.89
70 INT84369 Ngf Positive_regulation of KNG1 1 0.04 0.29 0.89
71 INT134454 EGF Positive_regulation of EGFR 3 0.56 1.32 0.88
72 INT96008 Binding of KNG1 and EBP 1 0.01 0.15 0.88
73 INT96010 KNG1 Positive_regulation of Binding of MTG1 1 0.32 0.15 0.88
74 INT134453 Negative_regulation of EGF Positive_regulation of EGFR 1 0.35 0.35 0.88
75 INT96009 KNG1 Positive_regulation of MTG1 1 0.32 0.15 0.88
76 INT196523 Binding of MMP2 and TIMP1 3 0.43 1.94 0.85
77 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
78 INT107698 FN1 Positive_regulation of Gene_expression of CPOX 1 0.13 0.26 0.84
79 INT167431 Binding of APP and MYO1C 1 0.23 1.38 0.83
80 INT225690 KNG1 Positive_regulation of TRPV1 1 0.42 0.7 0.83
81 INT153516 PLG Positive_regulation of Pas5a 1 0.57 0.05 0.83
82 INT116108 VEGFA Positive_regulation of SEC23IP 1 0.10 0.3 0.83
83 INT116109 VEGFA Positive_regulation of PTK2 1 0.13 0.3 0.83
84 INT193322 KNG1 Positive_regulation of Prh1 1 0.00 0.51 0.83
85 INT220739 EGF Positive_regulation of Transcription of NAV1 1 0.31 0.16 0.83
86 INT116106 VEGFA Positive_regulation of AKT1 1 0.12 0.3 0.83
87 INT218037 Binding of ALB and Penk 1 0.13 0 0.81
88 INT110726 Binding of ALB and LTF 1 0.01 0 0.81
89 INT84039 EGF Positive_regulation of Gene_expression of CPOX 2 0.11 1.88 0.8
90 INT84040 EGF Positive_regulation of CPOX 2 0.07 1.91 0.8
91 INT220747 Binding of PCa and EGF 1 0.05 1.42 0.8
92 INT108331 EGF Positive_regulation of Phosphorylation of BAD 1 0.49 6.72 0.8
93 INT150636 Binding of KNG1 and CD177 1 0.10 0.37 0.79
94 INT113546 Binding of FN1 and ITGA3 1 0.03 2.12 0.77
95 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
96 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
97 INT129415 KNG1 Positive_regulation of Trpv1 1 0.05 0.39 0.76
98 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
99 INT107028 KNG1 Regulation of Des 1 0.01 1.7 0.76
100 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
101 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75
102 INT161949 TGFB2 Positive_regulation of Gene_expression of Ngf 1 0.21 0.97 0.74
103 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74
104 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74
105 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73
106 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73
107 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
108 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73
109 INT243169 EGFL7 Positive_regulation of Gene_expression of PPBP 1 0.02 0.67 0.72
110 INT220746 EGF Positive_regulation of Gene_expression of GOPC 1 0.13 0 0.72
111 INT196526 Binding of TIMP1 and TIMP2 1 0.45 1.49 0.71
112 INT187115 Binding of TIMP1 and TNF 2 0.30 1.07 0.7
113 INT120018 VEGFA Positive_regulation of CCL3 1 0.01 1 0.7
114 INT120020 VEGFA Positive_regulation of CCL2 1 0.00 1 0.7
115 INT99818 IFNG Positive_regulation of Gene_expression of APP 1 0.04 0.82 0.7
116 INT346267 Binding of HGF and IL6 1 0.04 0.96 0.7
117 INT120036 VEGFA Positive_regulation of Prap1 1 0.00 1 0.7
118 INT28947 GH1 Positive_regulation of Gene_expression of IGF1 4 0.22 3.78 0.69
119 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69
120 INT121458 KNG1 Positive_regulation of Localization of Trpv1 1 0.16 0.43 0.69
121 INT303691 KNG1 Positive_regulation of AHR 1 0.03 0.98 0.69
122 INT303689 Regulation of KNG1 Positive_regulation of AHR 1 0.03 0.99 0.69
123 INT324900 VEGFA Positive_regulation of Gene_expression of Edn1 1 0.06 1.61 0.69
124 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
125 INT167355 VEGFA Regulation of RYBP 1 0.01 0.53 0.68
126 INT168295 PROC Regulation of Gene_expression of VEGFA 2 0.00 1.6 0.67
127 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
128 INT220738 EGF Regulation of Gene_expression of EGFR 1 0.09 0.6 0.67
129 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66
130 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
131 INT136815 VEGFA Positive_regulation of Positive_regulation of RHOA 1 0.44 0.06 0.65
132 INT45369 IGF1 Regulation of GH1 1 0.04 1.12 0.65
133 INT95546 KNG1 Positive_regulation of Ptgir 1 0.02 0.93 0.64
134 INT92045 Binding of ALB and SERPINA1 1 0.30 1.37 0.64
135 INT322385 PPBP Negative_regulation of Positive_regulation of OPRM1 1 0.00 0 0.64
136 INT96472 KNG1 Positive_regulation of Gene_expression of TRPV1 1 0.01 0.22 0.64
137 INT99728 Binding of F13A1 and PLG 4 0.02 2.51 0.63
138 INT34005 YY1 Regulation of KNG1 1 0.04 0.38 0.63
139 INT174860 VEGFA Positive_regulation of Localization of CCL2 1 0.21 1.68 0.63
140 INT333544 CTSB Regulation of Protein_catabolism of APP 1 0.01 0.53 0.62
141 INT121460 KNG1 Positive_regulation of Bdkrb2 1 0.08 0.44 0.62
142 INT182156 Binding of HGF and IL3RA 1 0.03 1.31 0.62
143 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
144 INT118083 Aip Negative_regulation of Phosphorylation of APP 1 0.00 0.75 0.62
145 INT121459 Bdkrb2 Positive_regulation of KNG1 1 0.09 0.44 0.62
146 INT333543 CTSB Regulation of APP 1 0.01 0.53 0.62
147 INT337323 KNG1 Positive_regulation of PRKCA 1 0.15 0.17 0.62
148 INT255690 Binding of VEGFA and Flt1 8 0.34 3.44 0.61
149 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61
150 INT224731 Binding of VEGFA and Cia1 1 0.01 0.91 0.61
151 INT224733 Negative_regulation of Binding of VEGFA and Cia1 1 0.01 0.91 0.61
152 INT98629 VEGFA Positive_regulation of Gene_expression of EGR1 1 0.52 0.42 0.61
153 INT98628 VEGFA Positive_regulation of Transcription of EGR1 1 0.52 0.42 0.61
154 INT169287 EGF Positive_regulation of Localization of IL8 1 0.15 0.13 0.61
155 INT284089 Binding of NTRK2 and SERPINE1 1 0.27 0.73 0.61
156 INT34840 Binding of KNG1 and PDYN 1 0.01 0 0.61
157 INT169294 EGF Positive_regulation of Localization of IL6 1 0.18 0.13 0.61
158 INT145661 Ptger2 Positive_regulation of Gene_expression of VEGFA 4 0.27 2.73 0.6
159 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6
160 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58
161 INT342624 VEGFA Negative_regulation of Mmp2 1 0.09 1.54 0.58
162 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58
163 INT120347 Binding of KNG1 and MYC 1 0.21 0.17 0.58
164 INT199976 EGF Regulation of ITGB3BP 1 0.02 0.77 0.57
165 INT304326 Ptger1 Positive_regulation of Gene_expression of VEGFA 1 0.19 1.37 0.57
166 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
167 INT192291 OR5A1 Positive_regulation of Gene_expression of IGF1 1 0.02 0.93 0.57
168 INT342621 VEGFA Negative_regulation of Timp2 1 0.09 1.53 0.57
169 INT175626 TIMP1 Positive_regulation of Gene_expression of MMP9 1 0.03 0.72 0.57
170 INT227928 Binding of MMRN1 and Lamb3 1 0.03 1.16 0.56
171 INT50883 Binding of AGTR2 and ALB 1 0.37 0.19 0.56
172 INT175627 TIMP1 Positive_regulation of MMP2 1 0.03 0.71 0.56
173 INT173555 TIMP1 Negative_regulation of MMP7 1 0.01 0 0.56
174 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56
175 INT175623 TIMP1 Positive_regulation of MMP9 1 0.03 0.71 0.56
176 INT173557 TIMP1 Negative_regulation of MMP3 1 0.02 0 0.56
177 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56
178 INT96098 Binding of PPBP and F2 1 0.00 1.31 0.56
179 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
180 INT544 Binding of ALB and GC 1 0.13 0 0.55
181 INT121994 EGF Positive_regulation of Positive_regulation of MAPK1 1 0.25 0 0.55
182 INT121993 Binding of EGF and SGCG 1 0.40 0 0.55
183 INT78030 Binding of VEGFC and FCAMR 1 0.01 0.31 0.55
184 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55
185 INT91428 CD44 Positive_regulation of Binding of MMRN1 1 0.24 0.85 0.55
186 INT126641 Binding of KNG1 and Bdkrb2 1 0.11 0.42 0.55
187 INT114029 Binding of ALB and Mmp3 1 0.01 0.31 0.55
188 INT351581 Binding of ALB and GOPC 1 0.11 0 0.55
189 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55
190 INT99736 Binding of PLG and Serpinf2 1 0.01 0.73 0.55
191 INT285758 RETNLB Positive_regulation of Gene_expression of TIMP1 1 0.01 1.79 0.55
192 INT114028 Negative_regulation of Binding of ALB and Mmp3 1 0.01 0.31 0.55
193 INT118082 APP Positive_regulation of Casp3 1 0.00 0.5 0.54
194 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
195 INT227908 Binding of COL7A1 and MMRN1 1 0.00 1.11 0.53
196 INT196522 Binding of MMP1 and TIMP1 1 0.39 0.29 0.53
197 INT150800 THBS3 Negative_regulation of SPARC 1 0.23 0.51 0.53
198 INT150791 THBS1 Negative_regulation of TIMP2 1 0.17 0.5 0.52
199 INT303721 KNG1 Positive_regulation of Bdkrb1 1 0.05 0.75 0.52
200 INT130561 NCKIPSD Regulation of SERPINF2 1 0.22 0 0.52

Single Events

The table below shows the top 100 pain related interactions that have been reported for platelet alpha granule lumen. They are ordered first by their pain relevance and then by number of times they were reported in platelet alpha granule lumen. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2
2 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73
4 INT8357 Gene_expression of KNG1 153 0.75 77.26 68.66
5 INT7134 Localization of KNG1 127 0.79 65.73 67.97
6 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07
7 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
8 INT546 Binding of ALB 311 0.48 85.98 60.14
9 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29
10 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74
11 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53
12 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75
13 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54
14 INT101992 Localization of VEGFA 413 0.81 258.23 36.15
15 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52
16 INT608 Negative_regulation of KNG1 98 0.43 72.36 31.23
17 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1
18 INT8097 Gene_expression of EGF 122 0.77 75.94 28.47
19 INT11361 Gene_expression of SERPINE1 183 0.78 136.45 27.97
20 INT3076 Regulation of KNG1 52 0.60 20.39 27.89
21 INT3167 Binding of KNG1 48 0.48 23.26 26.77
22 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7
23 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36
24 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14
25 INT44954 Gene_expression of APP 191 0.78 105.86 23.9
26 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
27 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
28 INT9079 Gene_expression of PPBP 52 0.75 31.2 21.52
29 INT48692 Binding of VEGFA 345 0.48 210.3 21.31
30 INT11157 Binding of EGF 88 0.48 53.73 21.25
31 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14
32 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86
33 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99
34 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9
35 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35
36 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
37 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03
38 INT23657 Positive_regulation of APP 64 0.70 39.76 16.68
39 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47
40 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26
41 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82
42 INT11636 Positive_regulation of SERPINE1 85 0.69 68.73 14.8
43 INT88544 Gene_expression of MMRN1 102 0.75 68.8 14.55
44 INT72127 Protein_catabolism of MMRN1 68 0.52 56 14.13
45 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98
46 INT18773 Localization of ALB 117 0.80 69.18 13.8
47 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68
48 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43
49 INT29745 Binding of APP 47 0.48 26.49 12.4
50 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32
51 INT55687 Localization of TIMP1 47 0.74 30.24 12.31
52 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99
53 INT4047 Binding of F13A1 105 0.43 66.54 11.81
54 INT14204 Protein_catabolism of KNG1 41 0.96 20.94 11.47
55 INT10049 Negative_regulation of SERPINA1 56 0.59 44.52 9.93
56 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9
57 INT2036 Localization of EGF 42 0.77 21.5 9.74
58 INT11729 Regulation of IGF1 71 0.61 44.58 9.71
59 INT4391 Gene_expression of SERPINA1 47 0.78 41.43 9.7
60 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69
61 INT11679 Negative_regulation of F13A1 55 0.54 33.69 9.43
62 INT41569 Regulation of APP 32 0.62 17.15 9.4
63 INT860 Regulation of ALB 48 0.60 25.11 8.95
64 INT34777 Localization of IGF1 82 0.80 42.68 8.62
65 INT16460 Negative_regulation of PPBP 21 0.57 13.86 8.54
66 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39
67 INT60034 Positive_regulation of VWF 40 0.68 30.42 8.15
68 INT26551 Positive_regulation of Gene_expression of KNG1 19 0.67 11.05 7.98
69 INT36678 Binding of TIMP1 33 0.36 14.99 7.87
70 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33
71 INT84932 Negative_regulation of APP 29 0.57 28.45 7.2
72 INT16618 Negative_regulation of SERPING1 81 0.59 86.28 7.17
73 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94
74 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9
75 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85
76 INT2037 Negative_regulation of EGF 30 0.59 15.05 6.81
77 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68
78 INT86805 Localization of HGF 49 0.71 28.48 6.35
79 INT4561 Gene_expression of PLG 32 0.75 17.59 6.21
80 INT5146 Localization of PPBP 32 0.81 12.5 6.08
81 INT34232 Regulation of TIMP1 37 0.61 18.76 6.05
82 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88
83 INT131378 Negative_regulation of FN1 20 0.35 33.98 5.85
84 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78
85 INT21647 Negative_regulation of Positive_regulation of KNG1 11 0.43 5.54 5.73
86 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61
87 INT32458 Gene_expression of VWF 57 0.78 28.97 5.56
88 INT187133 Protein_catabolism of TIMP1 19 0.73 11.3 5.51
89 INT11480 Positive_regulation of Localization of KNG1 15 0.30 6.39 5.5
90 INT37227 Regulation of EGF 19 0.45 11.16 5.17
91 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
92 INT99823 Positive_regulation of Gene_expression of APP 31 0.70 21.52 5.09
93 INT115816 Protein_catabolism of APP 35 0.99 20.14 5.06
94 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04
95 INT3647 Positive_regulation of Gene_expression of F13A1 20 0.41 15.71 5.02
96 INT17489 Regulation of F13A1 28 0.45 15.79 4.93
97 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9
98 INT10138 Negative_regulation of Gene_expression of KNG1 13 0.57 9.57 4.9
99 INT16214 Localization of F13A1 36 0.74 21.8 4.87
100 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81
101 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79
102 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77
103 INT144481 Gene_expression of SERPING1 55 0.77 50.4 4.75
104 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74
105 INT11354 Regulation of Gene_expression of SERPINE1 11 0.61 8.66 4.42
106 INT74531 Regulation of PDGFB 14 0.26 7.57 4.38
107 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
108 INT9080 Regulation of PPBP 17 0.44 5.75 4.3
109 INT11635 Positive_regulation of Gene_expression of SERPINE1 35 0.68 24.57 4.26
110 INT11634 Regulation of SERPINE1 24 0.62 20.06 4.26
111 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22
112 INT58003 Localization of APP 32 0.80 13.75 4.2
113 INT57273 Positive_regulation of Gene_expression of FN1 26 0.47 17.83 4.2
114 INT49217 Positive_regulation of Positive_regulation of KNG1 7 0.41 3.64 4.18
115 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17
116 INT88545 Localization of MMRN1 21 0.78 16.67 4.01
117 INT99821 Negative_regulation of Gene_expression of APP 20 0.42 15.21 3.94
118 INT44323 Positive_regulation of F8 32 0.60 24.88 3.89
119 INT51312 Positive_regulation of Gene_expression of SERPINA1 4 0.46 9.41 3.84
120 INT38033 Regulation of HGF 26 0.45 14.96 3.81
121 INT99819 Negative_regulation of Positive_regulation of APP 6 0.58 4.41 3.64
122 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
123 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
124 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52
125 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
126 INT8096 Positive_regulation of Gene_expression of EGF 21 0.69 13.43 3.47
127 INT70089 Negative_regulation of Binding of APP 7 0.59 6.45 3.44
128 INT220078 Positive_regulation of Negative_regulation of KNG1 3 0.13 5.03 3.41
129 INT70895 Localization of PDGFB 20 0.52 8.98 3.4
130 INT74946 Negative_regulation of Gene_expression of HGF 14 0.58 6.29 3.39
131 INT190208 Positive_regulation of MMRN1 15 0.23 14.1 3.37
132 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28
133 INT55690 Positive_regulation of Localization of TIMP1 8 0.50 4.77 3.28
134 INT22375 Localization of PDGFA 21 0.75 15.46 3.25
135 INT99687 Negative_regulation of Transcription of VEGFA 17 0.43 10.3 3.25
136 INT111547 Negative_regulation of Phosphorylation of VEGFA 13 0.42 5.08 3.22
137 INT61500 Binding of FN1 39 0.48 27.33 3.13
138 INT55409 Localization of VWF 17 0.80 8.99 3.06
139 INT131187 Regulation of Gene_expression of IGF1 18 0.62 11.18 3.05
140 INT19293 Protein_catabolism of FN1 7 0.95 5.15 2.97
141 INT14872 Gene_expression of TGFB3 15 0.55 12.45 2.96
142 INT16130 Binding of IGF1 67 0.48 27.43 2.95
143 INT91432 Binding of MMRN1 23 0.36 9.79 2.95
144 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
145 INT117785 Regulation of Gene_expression of EGF 7 0.44 4.22 2.87
146 INT10893 Binding of VWF 27 0.47 25.02 2.82
147 INT10141 Gene_expression of A2M 11 0.35 9.37 2.75
148 INT111298 Gene_expression of ACTN4 12 0.70 9.42 2.6
149 INT25449 Positive_regulation of Gene_expression of PPBP 5 0.46 3.77 2.57
150 INT74527 Positive_regulation of PDGFB 14 0.38 13.31 2.54
151 INT156130 Binding of SERPING1 29 0.42 26.16 2.52
152 INT100427 Binding of SERPINA1 9 0.36 9.63 2.51
153 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5
154 INT699 Positive_regulation of A2M 16 0.66 10.49 2.5
155 INT94010 Positive_regulation of Localization of VWF 9 0.70 4.23 2.5
156 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45
157 INT10048 Positive_regulation of SERPINA1 11 0.68 8.59 2.43
158 INT113164 Regulation of Regulation of VEGFA 6 0.36 5.96 2.43
159 INT31134 Regulation of Binding of ALB 13 0.62 2.51 2.37
160 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36
161 INT162513 Regulation of Protein_catabolism of APP 5 0.51 1.79 2.36
162 INT4560 Protein_catabolism of PLG 18 0.96 11.64 2.32
163 INT131456 Negative_regulation of MMRN1 14 0.19 9.49 2.29
164 INT19537 Negative_regulation of Binding of ALB 6 0.43 3.32 2.26
165 INT142626 Negative_regulation of Localization of ALB 9 0.55 6.63 2.24
166 INT150640 Regulation of Binding of KNG1 3 0.35 1.31 2.2
167 INT158016 Positive_regulation of VEGFC 7 0.49 6.58 2.18
168 INT23352 Negative_regulation of A2M 10 0.33 8.35 2.16
169 INT70962 Positive_regulation of SERPING1 33 0.69 27.32 2.14
170 INT82226 Negative_regulation of Gene_expression of EGF 11 0.58 6.36 2.13
171 INT103327 Gene_expression of F8 45 0.71 32.5 2.12
172 INT175655 Regulation of MMRN1 16 0.12 9.96 2.12
173 INT58108 Positive_regulation of Positive_regulation of ALB 4 0.70 1.02 2.11
174 INT108335 Phosphorylation of EGF 17 0.80 7.3 2.09
175 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
176 INT62711 Binding of HGF 27 0.31 15.23 2.08
177 INT36616 Positive_regulation of Binding of ALB 8 0.67 3 2.07
178 INT11390 Gene_expression of PF4 5 0.65 3.09 2.07
179 INT83911 Negative_regulation of Gene_expression of SERPINA1 3 0.43 5.2 2.07
180 INT17268 Localization of PLG 9 0.78 11.71 2.06
181 INT46109 Binding of SERPINF2 6 0.37 1.08 2.06
182 INT89240 Gene_expression of VEGFC 23 0.75 15.94 2.03
183 INT136818 Positive_regulation of Phosphorylation of VEGFA 4 0.46 0.81 2.02
184 INT35146 Negative_regulation of PLG 27 0.57 17.63 1.98
185 INT173851 Localization of FN1 20 0.76 13.95 1.97
186 INT213431 Positive_regulation of Gene_expression of MMRN1 15 0.24 9.91 1.96
187 INT132971 Negative_regulation of Localization of IGF1 5 0.42 3.98 1.94
188 INT57272 Negative_regulation of Gene_expression of FN1 16 0.43 11.42 1.93
189 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92
190 INT135616 Negative_regulation of Gene_expression of PPBP 6 0.26 2.58 1.91
191 INT88375 Negative_regulation of Localization of KNG1 4 0.39 1.12 1.91
192 INT62349 Negative_regulation of Protein_catabolism of KNG1 8 0.42 6.47 1.86
193 INT48722 Negative_regulation of Gene_expression of SERPINE1 12 0.43 7.66 1.85
194 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
195 INT60337 Positive_regulation of THBS1 8 0.46 4.69 1.83
196 INT222997 Positive_regulation of Localization of FN1 4 0.14 4.26 1.78
197 INT90800 Negative_regulation of Positive_regulation of EGF 5 0.40 2.78 1.77
198 INT201810 Gene_expression of LEFTY2 6 0.56 3.94 1.74
199 INT20347 Positive_regulation of PF4 5 0.67 2.91 1.72
200 INT130195 Positive_regulation of ACTN4 4 0.42 3.48 1.7
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