GO:0031115

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Name negative regulation of microtubule polymerization
Categary Process
Go Slim No
Go Link GO:0031115
Unique Molecular Interactions 30
Total Molecular Interactions 34
Total Single Events 487
Pain Genes Associated 10

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for negative regulation of microtubule polymerization. They are ordered first by their pain relevance and then by number of times they were reported for negative regulation of microtubule polymerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
2 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
3 INT18139 Binding of Penk and Stmn1 1 0.08 0 0.99
4 INT152947 Dlg4 Regulation of Sgk1 1 0.09 0.18 0.76
5 INT152949 Homer1 Regulation of Sgk1 1 0.28 0.18 0.76
6 INT191686 Igh-Dex Positive_regulation of Sgk1 1 0.04 1.79 0.46
7 INT319554 Sgk1 Regulation of Cdkn1a 1 0.26 0.09 0.45
8 INT328407 Nlrp1a Negative_regulation of Gene_expression of Snca 1 0.07 0.31 0.29
9 INT328410 Nlrp1a Negative_regulation of Snca 1 0.07 0.31 0.29
10 INT317322 Snca Regulation of Positive_regulation of Th 1 0.01 0.23 0.17
11 INT158141 Binding of HOXD13 and SNCA 1 0.54 0.41 0.11
12 INT328413 Binding of Snca and Nlrp1a 1 0.06 0.75 0.1
13 INT133661 Bdnf Regulation of Gene_expression of STMN2 1 0.14 0 0.09
14 INT83270 Snca Regulation of Napepld 1 0.14 0 0.09
15 INT133662 Bdnf Positive_regulation of Gene_expression of STMN2 1 0.20 0 0.05
16 INT318549 Positive_regulation of Stmn1 Positive_regulation of Gene_expression of Adamts1 1 0.01 0.73 0
17 INT329946 Binding of Stmn2 and Trpc5 1 0.03 0.15 0
18 INT317313 Atp13a2 Negative_regulation of Snca 1 0.13 0.59 0
19 INT318548 Adamts1 Regulation of Stmn1 1 0.00 1.3 0
20 INT180672 Sgk1 Regulation of Ecm1 1 0.03 0 0
21 INT317315 Gene_expression of Snca Negative_regulation of Psmb10 1 0.00 0.52 0
22 INT317320 Binding of Snca and Atp13a2 1 0.08 0.58 0
23 INT215702 Stmn1 Negative_regulation of Kras 1 0.00 0 0
24 INT318546 Positive_regulation of Stmn1 Positive_regulation of Adamts1 1 0.01 0.74 0
25 INT215704 Stmn1 Negative_regulation of Cdkn1c 1 0.00 0 0
26 INT215692 Stmn1 Negative_regulation of Cdkn1b 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for negative regulation of microtubule polymerization. They are ordered first by their pain relevance and then by number of times they were reported in negative regulation of microtubule polymerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
2 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
3 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
4 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
5 INT168151 Gene_expression of Sgk1 10 0.76 5.58 4.35
6 INT33035 Positive_regulation of Stmn1 5 0.30 0.56 4.24
7 INT191667 Positive_regulation of Sgk1 6 0.68 4.59 3.45
8 INT119412 Gene_expression of Snca 15 0.66 11.27 3.39
9 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36
10 INT18135 Regulation of Stmn1 2 0.17 0.15 3.24
11 INT123595 Regulation of Snca 7 0.62 4.3 3.06
12 INT228675 Binding of Fkbp4 1 0.01 1.14 2.28
13 INT233660 Transcription of Sgk1 3 0.70 0.51 2.03
14 INT127124 Regulation of Gene_expression of Snca 2 0.62 0.17 2.03
15 INT127125 Localization of Snca 6 0.81 8.24 1.88
16 INT53486 Gene_expression of Stmn1 6 0.34 4.21 1.75
17 INT148266 Positive_regulation of SNCA 5 0.67 3.17 1.74
18 INT86306 Binding of Stmn1 1 0.01 0 1.67
19 INT33037 Transcription of Stmn1 2 0.44 0.18 1.61
20 INT201271 Phosphorylation of Snca 3 0.82 4.22 1.45
21 INT89983 Gene_expression of STMN2 8 0.72 0 1.42
22 INT180712 Gene_expression of Sgk1 2 0.47 1.52 1.41
23 INT124247 Negative_regulation of Gene_expression of Snca 12 0.59 3.87 1.39
24 INT33038 Negative_regulation of Regulation of Stmn1 1 0.24 0.1 1.3
25 INT233665 Positive_regulation of Transcription of Sgk1 2 0.49 0.3 1.29
26 INT110244 Positive_regulation of Gene_expression of SNCA 5 0.69 4.66 1.19
27 INT139236 Regulation of Sgk1 2 0.37 0.84 1.14
28 INT151753 Transcription of Snca 6 0.69 1.99 1.11
29 INT326452 Gene_expression of Stmn2 1 0.55 0.65 1.11
30 INT233633 Negative_regulation of Positive_regulation of Sgk1 1 0.37 0.11 1.08
31 INT292945 Positive_regulation of Positive_regulation of Snca 4 0.69 2.42 1.05
32 INT33036 Regulation of Positive_regulation of Stmn1 1 0.17 0.06 1.05
33 INT286344 Positive_regulation of Gene_expression of Snca 1 0.41 2.84 1.03
34 INT233644 Negative_regulation of Sgk1 1 0.38 0.11 1.02
35 INT24809 Positive_regulation of Fkbp4 3 0.40 1.57 1
36 INT151752 Positive_regulation of Transcription of Snca 2 0.50 0.99 0.92
37 INT144543 Localization of Sgk1 1 0.71 0.96 0.91
38 INT124246 Binding of Snca 10 0.37 6.53 0.9
39 INT117444 Regulation of Sgk1 4 0.60 1.35 0.87
40 INT233632 Regulation of Transcription of Sgk1 1 0.39 0.22 0.78
41 INT247255 Positive_regulation of Gene_expression of Sgk1 1 0.30 0.84 0.72
42 INT89985 Transcription of STMN2 5 0.50 0 0.64
43 INT119429 Negative_regulation of Stmn1 2 0.29 0.17 0.63
44 INT144545 Positive_regulation of Sgk1 1 0.44 0.62 0.59
45 INT191670 Positive_regulation of Gene_expression of Sgk1 1 0.33 2.42 0.46
46 INT319552 Regulation of Gene_expression of Sgk1 1 0.60 0 0.44
47 INT125586 Gene_expression of Stmn1 13 0.75 8.28 0.42
48 INT148264 Transcription of SNCA 1 0.40 0.25 0.42
49 INT343972 Negative_regulation of Binding of SNCA 1 0.36 0.2 0.39
50 INT169628 Binding of SNCA 4 0.47 3.53 0.36
51 INT343973 Localization of SNCA 1 0.63 0.07 0.3
52 INT89984 Regulation of Gene_expression of STMN2 1 0.57 0 0.26
53 INT142052 Binding of Snca 4 0.47 1.02 0.22
54 INT292944 Regulation of Positive_regulation of Snca 1 0.45 0.36 0.21
55 INT133659 Positive_regulation of Gene_expression of STMN2 1 0.65 0 0.19
56 INT257418 Negative_regulation of Transcription of Snca 1 0.43 0.93 0.19
57 INT89982 Regulation of Transcription of STMN2 1 0.02 0 0.18
58 INT166361 Phosphorylation of SNCA 1 0.70 0.72 0.17
59 INT319544 Localization of Sgk1 1 0.73 0.34 0.16
60 INT157084 Localization of Snca 1 0.51 0.17 0.16
61 INT343974 Negative_regulation of Gene_expression of SNCA 1 0.31 0.09 0.16
62 INT319289 Protein_catabolism of Snca 1 0.35 0.93 0.15
63 INT286343 Negative_regulation of Gene_expression of Snca 1 0.26 0.65 0.15
64 INT200259 Negative_regulation of Negative_regulation of Stmn2 1 0.11 0.45 0.11
65 INT200253 Negative_regulation of Stmn2 1 0.16 0.45 0.11
66 INT133658 Negative_regulation of Gene_expression of STMN2 1 0.40 0 0.1
67 INT133657 Negative_regulation of Transcription of STMN2 1 0.40 0 0.1
68 INT133660 Positive_regulation of STMN2 1 0.56 0 0.09
69 INT117441 Negative_regulation of Regulation of Sgk1 1 0.43 0.19 0.09
70 INT288642 Negative_regulation of Positive_regulation of Snca 1 0.07 0.93 0.09
71 INT125587 Positive_regulation of Gene_expression of Stmn1 9 0.67 4.2 0.08
72 INT292946 Positive_regulation of Localization of Snca 1 0.50 0.52 0.06
73 INT303299 Positive_regulation of Stmn1 2 0.32 4.58 0
74 INT332379 Negative_regulation of Phosphorylation of Stmn1 1 0.39 0 0
75 INT332385 Phosphorylation of Stmn1 1 0.76 0 0
76 INT317275 Positive_regulation of Binding of Snca 1 0.37 0.53 0
77 INT343971 Positive_regulation of Positive_regulation of SNCA 1 0.42 0.35 0
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