GO:0031116

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Name positive regulation of microtubule polymerization
Categary Process
Go Slim No
Go Link GO:0031116
Unique Molecular Interactions 350
Total Molecular Interactions 456
Total Single Events 3172
Pain Genes Associated 19

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of microtubule polymerization. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of microtubule polymerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT168715 Mapk8 Negative_regulation of Oprk1 1 0.18 0.26 1.75
2 INT168716 Mapk8 Negative_regulation of Insrr 1 0.01 0.25 1.75
3 INT167427 Mapk8 Regulation of Regulation of Tnf 1 0.26 2.83 1.7
4 INT21570 Binding of Cck and Mapk8 1 0.06 0 1.6
5 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
6 INT161509 Tlr4 Positive_regulation of Mapk8 1 0.15 0.3 1.16
7 INT167429 Negative_regulation of Mapk8 Negative_regulation of RYBP 1 0.01 1.11 1.09
8 INT139703 Tnf Positive_regulation of Mapk8 1 0.32 0.73 1.08
9 INT223875 Negative_regulation of Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.31 0 1.07
10 INT92404 PSRC1 Regulation of CDKN1A 1 0.33 0.66 0.89
11 INT305406 Binding of CAV3 and ST8SIA2 1 0.16 0 0.86
12 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79
13 INT152234 Mapk8 Positive_regulation of Localization of Nfkb1 1 0.33 0.26 0.78
14 INT152235 Mapk8 Positive_regulation of Localization of Tlr4 1 0.38 0.26 0.78
15 INT98179 Aap Positive_regulation of Mapk8 1 0.01 0.75 0.74
16 INT168420 Positive_regulation of Mapk8 Positive_regulation of Phosphorylation of Jun 1 0.30 0.88 0.74
17 INT128813 Mapk8 Regulation of Gene_expression of Nos2 1 0.23 0.46 0.74
18 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73
19 INT223873 Mapk8 Regulation of Positive_regulation of Ltp 1 0.24 0 0.71
20 INT223869 Mapk8 Negative_regulation of Positive_regulation of Ltp 1 0.20 0 0.68
21 INT110458 Binding of Atf2 and Mapk8 1 0.35 0 0.66
22 INT330046 Mapk8 Negative_regulation of Prkcg 1 0.13 0.4 0.66
23 INT100030 TNF Positive_regulation of Mapk8 1 0.12 1.57 0.63
24 INT166398 CDKN1B Regulation of Gene_expression of CDKN1A 1 0.46 0.83 0.61
25 INT166399 CDKN1A Regulation of Gene_expression of CDKN1B 1 0.46 0.83 0.61
26 INT128812 Mapk8 Negative_regulation of Gene_expression of Nos2 1 0.19 0.37 0.61
27 INT92403 PSRC1 Regulation of Positive_regulation of CDKN1A 1 0.33 0.45 0.6
28 INT178437 Mapk8 Positive_regulation of Jun 3 0.40 2.69 0.58
29 INT200913 Dio1 Positive_regulation of Mapk8 1 0.00 0 0.53
30 INT221630 Binding of Fes and Plxna1 1 0.01 1.02 0.5
31 INT182150 Binding of APC and DCPS 1 0.02 1.14 0.48
32 INT114297 Apc Negative_regulation of Gene_expression of Fcer2a 1 0.03 0.96 0.48
33 INT352892 Binding of CAV1 and ITGA2 1 0.20 1.61 0.47
34 INT254225 Mapk14 Positive_regulation of Mapk8 1 0.02 0.87 0.46
35 INT254198 Mapk1 Positive_regulation of Mapk8 1 0.01 0.87 0.46
36 INT69637 Binding of CAV1 and Zfp354a 1 0.00 0 0.46
37 INT264476 Il1a Positive_regulation of Gene_expression of Mapk8 1 0.04 0 0.43
38 INT264475 Il1a Positive_regulation of Mapk8 1 0.04 0 0.43
39 INT319312 Socs4 Positive_regulation of Mapk8 1 0.05 0.68 0.41
40 INT179938 Negative_regulation of Mapk8 Negative_regulation of TNF 1 0.02 1.09 0.37
41 INT187233 Positive_regulation of Mapk8 Positive_regulation of Jun 1 0.12 0.92 0.37
42 INT264480 Il1a Positive_regulation of Phosphorylation of Mapk8 1 0.04 0 0.37
43 INT84887 APC Negative_regulation of Gene_expression of PPARD 1 0.36 0.55 0.37
44 INT309120 Edc4 Negative_regulation of Positive_regulation of Mapk8 1 0.01 1.03 0.36
45 INT199285 Tg(Foxn1)E1Hon Regulation of Gene_expression of Mapt 1 0.01 0.52 0.36
46 INT308653 Proc Regulation of Gene_expression of Mapk8 1 0.00 1.48 0.36
47 INT330106 Racgap1 Positive_regulation of Positive_regulation of Mapk8 1 0.01 1.32 0.35
48 INT330105 Rac1 Positive_regulation of Mapk8 1 0.15 1.47 0.34
49 INT330103 Rac1 Positive_regulation of Positive_regulation of Mapk8 1 0.14 1.24 0.32
50 INT348016 Binding of Mapk8 and Mapk8ip3 1 0.04 2.09 0.32
51 INT195665 APC Negative_regulation of F8 1 0.04 1.53 0.32
52 INT242164 Wnt2 Positive_regulation of Localization of Apc 1 0.13 1.53 0.32
53 INT110461 Binding of Mapk8 and Gtf3a 1 0.03 0 0.32
54 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
55 INT166391 IFI27 Regulation of Gene_expression of CDKN1B 1 0.33 0.41 0.31
56 INT282421 Mapk8 Negative_regulation of Ins1 1 0.06 2.48 0.31
57 INT220521 Ugt1a6b Positive_regulation of Cdkn1b 1 0.01 2.38 0.31
58 INT195664 APC Negative_regulation of F5 1 0.08 1.51 0.31
59 INT253153 TNF Positive_regulation of Mapk8 1 0.18 0.61 0.31
60 INT167983 Mapk8 Negative_regulation of gr 1 0.02 0.5 0.31
61 INT166397 CDKN1B Regulation of Gene_expression of IFI27 1 0.33 0.41 0.31
62 INT253155 TNF Positive_regulation of Positive_regulation of Mapk8 1 0.19 0.62 0.31
63 INT63122 Binding of APC and Man2a2 1 0.01 0.15 0.3
64 INT224131 Binding of CAV1 and Agtr1a 1 0.00 0.08 0.3
65 INT159964 Tnf Positive_regulation of Phosphorylation of Mapk8 1 0.11 0.94 0.29
66 INT226505 Il1rl1 Positive_regulation of Mapk8 1 0.04 0.4 0.29
67 INT226509 Il1rl1 Positive_regulation of Gene_expression of Mapk8 1 0.05 0.4 0.29
68 INT309122 Edc4 Positive_regulation of Phosphorylation of Mapk8 1 0.02 0.73 0.28
69 INT289954 Binding of APC and CD28 1 0.03 0.38 0.28
70 INT141870 Binding of Slc2a4 and Cav1 1 0.36 0.38 0.28
71 INT132368 Mapk8 Positive_regulation of Nfkb1 1 0.17 0.11 0.27
72 INT132369 Mapk8 Positive_regulation of Positive_regulation of Nfkb1 1 0.18 0.12 0.27
73 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27
74 INT132366 Lgals1 Positive_regulation of Mapk8 1 0.38 0.13 0.27
75 INT132370 Mapk8 Positive_regulation of Ephb1 1 0.15 0.12 0.27
76 INT179928 Binding of Ephb1 and Mapk8 1 0.11 0.91 0.26
77 INT130056 PPARG Positive_regulation of CAV1 1 0.02 0.53 0.25
78 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24
79 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24
80 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24
81 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24
82 INT330053 Binding of Ros1 and Mapk8 1 0.02 0.88 0.24
83 INT95741 Creb1 Regulation of Mapk8 1 0.39 0 0.23
84 INT109408 Negative_regulation of APC Negative_regulation of Positive_regulation of RASGRP1 1 0.06 0.73 0.23
85 INT250783 APC Negative_regulation of SERPINE1 1 0.06 0.86 0.23
86 INT250782 APC Negative_regulation of F2 1 0.00 0.86 0.23
87 INT316111 APC Negative_regulation of SAE1 1 0.04 1.21 0.22
88 INT288582 Binding of Cav1 and Kcnma1 1 0.11 0 0.22
89 INT309124 Dlat Negative_regulation of Positive_regulation of Mapk8 1 0.02 0.27 0.22
90 INT220528 Ugt1a6b Positive_regulation of Cav1 1 0.01 1.31 0.22
91 INT309116 Edc4 Negative_regulation of Mapk8 1 0.01 0.43 0.22
92 INT195663 APC Negative_regulation of Gene_expression of IL6 1 0.16 1.18 0.22
93 INT330051 Mapk8 Positive_regulation of Bcl2l11 1 0.13 0.46 0.21
94 INT221642 Binding of Fes and Fer 1 0.32 0.27 0.2
95 INT316110 Binding of APC and SAE1 1 0.03 1.16 0.2
96 INT131718 Mapk8 Regulation of Penk 1 0.46 0.16 0.2
97 INT266414 Binding of HMGB1 and Mapk8 1 0.03 0.91 0.2
98 INT221641 Binding of Dpysl2 and Fes 1 0.23 0.27 0.2
99 INT322543 Binding of FOXO3 and Cdkn1b 1 0.08 0.84 0.19
100 INT179935 Binding of Jun and Mapk8 1 0.04 0.61 0.19
101 INT222023 Gpx3 Regulation of Mapk8 1 0.01 1.43 0.18
102 INT299370 Binding of Mapk8 and Life1 1 0.04 0.73 0.18
103 INT284445 Dep1 Positive_regulation of Mapk8 1 0.00 0.58 0.17
104 INT220520 Ugt1a6b Positive_regulation of Gene_expression of Cav1 1 0.01 0.81 0.17
105 INT334106 APC Negative_regulation of NFKB1 1 0.25 1.37 0.17
106 INT334108 APC Negative_regulation of TNF 1 0.13 1.36 0.17
107 INT149281 Binding of MAPT and Dbp 1 0.00 0.4 0.17
108 INT348034 Mapk8ip3 Negative_regulation of Mapk8 1 0.05 0.98 0.16
109 INT255736 Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.14 2.31 0.16
110 INT282708 Binding of MAPT and Y301C7L 1 0.00 0.54 0.16
111 INT348019 Negative_regulation of Binding of Mapk8 and Mapk8ip3 1 0.05 1.04 0.16
112 INT221632 Plxna1 Negative_regulation of Fes 1 0.02 0.58 0.15
113 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15
114 INT179934 Mapk8 Regulation of Gene_expression of Mmp9 1 0.06 0.48 0.15
115 INT302146 CDKN2A Regulation of CDKN1B 1 0.11 0.51 0.14
116 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14
117 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14
118 INT221662 Fes Positive_regulation of Phosphorylation of Dpysl2 1 0.24 0.14 0.14
119 INT289956 Binding of APC and ICAM1 1 0.04 0.5 0.13
120 INT242163 Wnt2 Positive_regulation of Regulation of Apc 1 0.13 0.71 0.13
121 INT221615 Dpysl2 Positive_regulation of Gene_expression of Fes 1 0.21 0.14 0.13
122 INT184603 APC Negative_regulation of Gene_expression of TNF 1 0.09 0.97 0.13
123 INT266531 Mapk8 Positive_regulation of Phosphorylation of Olr447 1 0.00 0 0.13
124 INT182886 Ros1 Positive_regulation of Mapk8 3 0.09 2.3 0.12
125 INT221620 Fes Regulation of Gh 1 0.01 0.39 0.12
126 INT221634 Fes Regulation of Ngf 1 0.28 0.33 0.12
127 INT316190 Apc Negative_regulation of Positive_regulation of Mapk1 1 0.33 0.66 0.12
128 INT182481 Binding of Cav1 and Ighg2b 1 0.10 0 0.12
129 INT182482 Binding of Cav1 and Cxcl16 1 0.07 0 0.12
130 INT184608 APC Regulation of Gene_expression of Nppa 1 0.06 1.11 0.12
131 INT352467 Dusp1 Negative_regulation of Mapk8 1 0.02 0.23 0.12
132 INT299754 Binding of APC and CTLA4 2 0.08 0.97 0.11
133 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11
134 INT348786 Tlr4 Positive_regulation of Mapk8 1 0.33 1.09 0.11
135 INT143648 Negative_regulation of Mapk8 Negative_regulation of Gene_expression of Fas 1 0.39 0.21 0.11
136 INT266904 Plat Positive_regulation of Positive_regulation of Mapk8 1 0.03 0.6 0.11
137 INT255811 Binding of GNAS and MAPT 1 0.00 0.67 0.11
138 INT181076 Map4k4 Positive_regulation of Mapk8 1 0.11 0.47 0.11
139 INT221659 Binding of Fes and Dpysl5 1 0.16 0.58 0.11
140 INT240903 Mapk8 Positive_regulation of Ros1 2 0.09 1.01 0.1
141 INT181569 Binding of Edn1 and Mapk8 1 0.09 2.7 0.1
142 INT220517 Negative_regulation of Ugt1a6b Positive_regulation of Cav1 1 0.01 0.35 0.1
143 INT348042 Positive_regulation of Mapk8 Regulation of Gene_expression of VEGFA 1 0.03 0.85 0.1
144 INT262255 Binding of APC and F2R 1 0.05 3 0.1
145 INT233858 CHKA Positive_regulation of Gene_expression of CDKN1B 1 0.10 0.17 0.09
146 INT302977 Binding of Cav1 and Smpd2 1 0.08 0.71 0.09
147 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
148 INT348025 Mapk8 Regulation of Gene_expression of Proc 1 0.00 0.58 0.08
149 INT270203 Binding of CD28 and Apc 1 0.04 0.58 0.08
150 INT309159 Binding of Cav1 and Positive_regulation of Localization of Esr1 1 0.04 0 0.08
151 INT301631 Gene_expression of Mapk8 Positive_regulation of Phosphorylation of Irs1 1 0.09 0.72 0.08
152 INT221655 Plxna1 Negative_regulation of Phosphorylation of Fes 1 0.02 0.17 0.08
153 INT270197 Binding of Apc and Cd86 1 0.02 0.58 0.08
154 INT220514 Ppara Positive_regulation of Gene_expression of Cdkn1b 1 0.08 1 0.08
155 INT270198 Binding of Apc and Cd80 1 0.02 0.58 0.08
156 INT301659 Gene_expression of Mapk8 Positive_regulation of Positive_regulation of Srebf1 1 0.33 0.8 0.08
157 INT325274 IL1RAP Positive_regulation of Mapk8 1 0.14 0 0.07
158 INT221631 Dpysl2 Negative_regulation of Fes 1 0.21 0.42 0.07
159 INT325262 Il1rap Positive_regulation of Mapk8 1 0.09 0 0.07
160 INT302150 MRPL28 Regulation of CDKN1B 1 0.09 0.26 0.06
161 INT207629 Binding of Mtap1b and Cabp1 1 0.30 0 0.06
162 INT266388 S100a6 Negative_regulation of Mapk8 1 0.03 0.49 0.06
163 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
164 INT302136 LAMTOR1 Regulation of CDKN1B 1 0.08 0.26 0.06
165 INT257879 Negative_regulation of Eif4e Positive_regulation of Cdkn1b 1 0.28 0.54 0.06
166 INT178438 Mapk8 Positive_regulation of Plau 1 0.06 0.52 0.06
167 INT348030 Mapk8 Regulation of Re 1 0.17 0.95 0.06
168 INT218676 Mapk8 Regulation of Mapk14 1 0.00 0.33 0.05
169 INT181571 Binding of Mapk8 and Mapk1 1 0.04 1.24 0.05
170 INT183853 Gene_expression of CAV1 Negative_regulation of Positive_regulation of MAPK1 1 0.28 0.25 0.05
171 INT176095 Binding of Apc and EC 1 0.04 0.51 0.05
172 INT204079 HP Positive_regulation of Gene_expression of Cdkn1b 1 0.00 0.6 0.05
173 INT218703 Mapk8 Regulation of EPHB2 1 0.04 0.33 0.05
174 INT302133 IFI27 Regulation of CDKN1B 1 0.11 0.26 0.05
175 INT242974 Mapk8 Negative_regulation of Positive_regulation of Esr1 1 0.01 1.39 0.05
176 INT302130 CDKN1A Regulation of CDKN1B 1 0.04 0.26 0.05
177 INT221663 Fes Positive_regulation of Binding of Plxna1 1 0.02 0.4 0.05
178 INT302141 CDKN1C Regulation of CDKN1B 1 0.09 0.26 0.05
179 INT218667 Olr811 Regulation of Mapk8 1 0.00 0.33 0.05
180 INT120574 Binding of Apc and Egfr 1 0.27 1.02 0.05
181 INT334107 Binding of APC and APCS 1 0.16 1.52 0.04
182 INT178443 Negative_regulation of Mapk8 Positive_regulation of Negative_regulation of Mapk14 1 0.13 0.76 0.04
183 INT274078 Binding of Mapk8 and Gmcl1 1 0.05 0.68 0.04
184 INT248703 Mapk8 Positive_regulation of Phosphorylation of Rxrb 1 0.01 0.25 0.04
185 INT221654 Fes Positive_regulation of Phosphorylation of Crmp1 1 0.18 0.37 0.04
186 INT179927 Litaf Positive_regulation of Mapk8 1 0.02 0.39 0.04
187 INT301647 Negative_regulation of Mapk8 Positive_regulation of Irs1 1 0.08 0.83 0.04
188 INT301626 Mapk8 Positive_regulation of Irs1 1 0.09 0.83 0.04
189 INT321683 Binding of Aicda and Mapt 1 0.36 1.23 0.04
190 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
191 INT220512 Cav1 Regulation of Positive_regulation of Cdkn1b 1 0.06 0.85 0.03
192 INT299368 Mkks Positive_regulation of Mapk8 1 0.41 0.17 0.03
193 INT248698 Mapk8 Positive_regulation of Ppm1e 1 0.00 0.31 0.03
194 INT221623 Fyn Regulation of Fes 1 0.14 0.2 0.03
195 INT248706 Mapk8 Positive_regulation of Nr1i3 1 0.00 0.3 0.03
196 INT348017 Mapk8 Positive_regulation of Positive_regulation of Vps54 1 0.02 0.89 0.03
197 INT170910 Negative_regulation of Pcbd1 Positive_regulation of Positive_regulation of Mapk8 1 0.00 0.21 0.03
198 INT207644 Binding of Car2 and Mtap1b 1 0.04 0 0.03
199 INT248699 Mapk8 Positive_regulation of Nr0b2 1 0.01 0.3 0.03
200 INT183896 Gene_expression of CAV1 Negative_regulation of Positive_regulation of Racgap1 1 0.01 0.64 0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of microtubule polymerization. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of microtubule polymerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT84260 Positive_regulation of Mapk8 124 0.69 72.84 35.98
2 INT95734 Phosphorylation of Mapk8 108 0.82 49.92 33.52
3 INT96913 Positive_regulation of Mapk8 179 0.69 130.44 32.2
4 INT99068 Gene_expression of Mapk8 62 0.78 33.57 21.25
5 INT109316 Negative_regulation of Mapk8 72 0.59 50.59 17.24
6 INT104493 Negative_regulation of Mapk8 56 0.53 27.76 16.86
7 INT95738 Positive_regulation of Phosphorylation of Mapk8 40 0.70 23.46 13.88
8 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75
9 INT109315 Gene_expression of Mapk8 70 0.78 45.46 11.65
10 INT96915 Phosphorylation of Mapk8 73 0.81 40.69 11.44
11 INT145695 Regulation of Mapk8 26 0.62 14.67 9.83
12 INT111998 Positive_regulation of Positive_regulation of Mapk8 23 0.69 9.33 8.97
13 INT57057 Gene_expression of APC 131 0.78 122.24 8.7
14 INT168096 Transcription of Cav3 1 0.72 7.23 8.58
15 INT104481 Regulation of Mapk8 21 0.50 13.87 8.41
16 INT96912 Positive_regulation of Phosphorylation of Mapk8 29 0.69 18.33 8.14
17 INT99071 Positive_regulation of Gene_expression of Mapk8 16 0.55 9.87 7.58
18 INT16631 Negative_regulation of APC 46 0.57 30.53 7.11
19 INT8595 Localization of Mapt 26 0.73 6.81 6.41
20 INT3819 Positive_regulation of Apc 36 0.69 27.03 6.02
21 INT128922 Negative_regulation of Gene_expression of Mapk8 6 0.34 3.93 5.36
22 INT87022 Gene_expression of Apc 68 0.67 46.98 5.22
23 INT135291 Positive_regulation of Positive_regulation of Mapk8 24 0.64 19.37 5.16
24 INT99549 Gene_expression of CDKN1B 30 0.75 17 5.15
25 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08
26 INT131717 Positive_regulation of Gene_expression of Mapk8 18 0.55 14.25 5.02
27 INT75627 Gene_expression of Mapt 41 0.75 22.1 4.58
28 INT141443 Phosphorylation of Cav1 6 0.82 4.39 4.03
29 INT3817 Negative_regulation of Apc 29 0.58 22.12 3.91
30 INT153666 Gene_expression of CAV1 156 0.77 120.99 3.9
31 INT63121 Binding of APC 29 0.41 23.02 3.8
32 INT21569 Binding of Mapk8 8 0.48 5.55 3.44
33 INT163529 Negative_regulation of Positive_regulation of Mapk8 14 0.43 8.37 3.2
34 INT110755 Negative_regulation of Positive_regulation of Mapk8 15 0.46 9.91 2.98
35 INT86703 Positive_regulation of Gene_expression of Cav1 7 0.70 3.58 2.73
36 INT95735 Regulation of Phosphorylation of Mapk8 7 0.50 1.88 2.69
37 INT95739 Negative_regulation of Phosphorylation of Mapk8 11 0.42 6.77 2.61
38 INT99548 Positive_regulation of Gene_expression of CDKN1B 12 0.67 6.79 2.5
39 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47
40 INT136614 Positive_regulation of Cav1 5 0.46 2.28 2.23
41 INT111038 Gene_expression of Cdkn1b 23 0.75 25.35 2.22
42 INT168959 Gene_expression of CAV3 5 0.65 0.7 2.2
43 INT156270 Regulation of Positive_regulation of Mapk8 3 0.41 2.31 2.08
44 INT152696 Negative_regulation of Negative_regulation of Mapk8 1 0.32 0.35 2
45 INT109313 Binding of Mapk8 6 0.48 1.78 1.98
46 INT112089 Gene_expression of Cav1 73 0.75 23.8 1.97
47 INT96916 Negative_regulation of Phosphorylation of Mapk8 16 0.52 9.68 1.97
48 INT99547 Positive_regulation of CDKN1B 18 0.67 8.42 1.96
49 INT98782 Gene_expression of Cdkn1b 70 0.75 36.43 1.9
50 INT164864 Positive_regulation of Negative_regulation of Mapk8 1 0.31 1.33 1.82
51 INT89618 Positive_regulation of Map1b 1 0.68 2.48 1.81
52 INT299365 Transcription of Mapk8 9 0.72 5.91 1.75
53 INT141444 Positive_regulation of Phosphorylation of Cav1 1 0.70 1.76 1.69
54 INT3818 Regulation of Apc 13 0.39 12.52 1.68
55 INT168964 Negative_regulation of Gene_expression of CAV3 1 0.47 0 1.68
56 INT168714 Negative_regulation of Binding of Mapk8 1 0.36 0.18 1.62
57 INT107341 Phosphorylation of MAPT 19 0.80 14 1.61
58 INT135955 Positive_regulation of Cav1 17 0.48 7.73 1.61
59 INT137505 Positive_regulation of Cdkn1b 18 0.67 10.55 1.54
60 INT221560 Gene_expression of Fes 36 0.72 6.63 1.51
61 INT220177 Binding of Apc 21 0.37 15.34 1.37
62 INT110434 Positive_regulation of Gene_expression of Apc 20 0.50 11.37 1.3
63 INT61999 Gene_expression of MAPT 19 0.75 15.4 1.3
64 INT160009 Transcription of CDKN1B 2 0.67 1.43 1.29
65 INT141862 Binding of Cav1 11 0.36 1.32 1.25
66 INT114220 Negative_regulation of Gene_expression of Cdkn1b 4 0.33 4.11 1.23
67 INT154048 Negative_regulation of Gene_expression of Mapk8 5 0.43 4.43 1.22
68 INT168095 Positive_regulation of Transcription of Cav3 1 0.47 0.91 1.2
69 INT63923 Binding of Mapt 4 0.47 6.28 1.19
70 INT102073 Regulation of Gene_expression of APC 5 0.45 6.09 1.15
71 INT139764 Negative_regulation of CAV1 10 0.58 6.57 1.14
72 INT102074 Positive_regulation of Gene_expression of APC 20 0.50 13.66 1.1
73 INT160008 Positive_regulation of Transcription of CDKN1B 1 0.49 0.98 1.1
74 INT111036 Positive_regulation of Cdkn1b 16 0.45 9 1.06
75 INT111037 Positive_regulation of Gene_expression of Cdkn1b 5 0.39 11.17 1.06
76 INT168957 Positive_regulation of CAV3 1 0.40 0 1.06
77 INT168960 Binding of CAV3 1 0.30 0 1.05
78 INT160012 Regulation of Gene_expression of CDKN1B 2 0.44 1.17 1.04
79 INT63922 Positive_regulation of Binding of Mapt 1 0.49 0.25 1.01
80 INT8594 Negative_regulation of Mapt 5 0.57 4.47 0.98
81 INT136613 Negative_regulation of Cav1 2 0.57 2.28 0.96
82 INT141936 Phosphorylation of Mapt 14 0.80 10.59 0.95
83 INT149903 Localization of Cav3 3 0.80 1.1 0.93
84 INT153670 Positive_regulation of Gene_expression of CAV1 26 0.69 44.27 0.92
85 INT242134 Localization of Apc 8 0.74 4.83 0.88
86 INT141442 Negative_regulation of Phosphorylation of Cav1 1 0.59 0.94 0.87
87 INT200900 Localization of Mapk8 9 0.40 5.76 0.84
88 INT221543 Binding of Fes 1 0.45 1.79 0.83
89 INT149905 Negative_regulation of Cav3 2 0.43 0.98 0.82
90 INT220498 Negative_regulation of Gene_expression of Cdkn1b 9 0.21 7.48 0.8
91 INT112090 Negative_regulation of Gene_expression of Cav1 8 0.57 3.5 0.78
92 INT130057 Positive_regulation of CAV1 12 0.65 8.96 0.77
93 INT165104 Negative_regulation of Negative_regulation of Mapk8 5 0.43 4.21 0.77
94 INT165105 Localization of Mapk8 7 0.69 4.45 0.76
95 INT221557 Phosphorylation of Fes 1 0.76 2.49 0.76
96 INT68297 Binding of MAPT 9 0.47 4.45 0.75
97 INT164489 Regulation of Gene_expression of Mapk8 2 0.44 0.65 0.74
98 INT112088 Regulation of Cav1 2 0.44 0.51 0.73
99 INT57062 Regulation of APC 24 0.58 14.3 0.7
100 INT89621 Gene_expression of Map1b 1 0.76 1.48 0.7
101 INT80674 Negative_regulation of Gene_expression of APC 16 0.59 18.14 0.69
102 INT153667 Localization of CAV1 15 0.76 11.92 0.68
103 INT34187 Localization of MAPT 1 0.78 0 0.65
104 INT34186 Positive_regulation of Localization of MAPT 1 0.49 0 0.65
105 INT241621 Regulation of Cdkn1b 2 0.06 0.36 0.62
106 INT168963 Negative_regulation of Binding of CAV3 1 0.30 0 0.62
107 INT168962 Positive_regulation of Localization of CAV3 1 0.40 0 0.62
108 INT168953 Localization of CAV3 1 0.60 0 0.62
109 INT86700 Regulation of Cav1 7 0.54 0.92 0.61
110 INT113850 Negative_regulation of Cdkn1b 4 0.42 3.45 0.6
111 INT131001 Regulation of CAV1 6 0.44 3.77 0.59
112 INT14318 Negative_regulation of MAPT 3 0.57 2.05 0.59
113 INT141863 Negative_regulation of Gene_expression of Cav1 4 0.49 1.77 0.58
114 INT168955 Phosphorylation of CAV3 1 0.56 0 0.58
115 INT98786 Positive_regulation of Gene_expression of Cdkn1b 21 0.67 8.7 0.56
116 INT14317 Negative_regulation of Negative_regulation of MAPT 1 0.41 0.28 0.56
117 INT120358 Positive_regulation of Positive_regulation of CDKN1B 2 0.49 1.26 0.55
118 INT118716 Positive_regulation of MAPT 4 0.49 7.25 0.54
119 INT72869 Regulation of Negative_regulation of APC 2 0.36 1.7 0.54
120 INT163828 Localization of Cdkn1b 4 0.66 5.2 0.48
121 INT86702 Localization of Cav1 8 0.69 0.76 0.47
122 INT151720 Negative_regulation of Positive_regulation of Apc 3 0.37 2.15 0.46
123 INT153672 Negative_regulation of Negative_regulation of CAV1 1 0.25 0.2 0.46
124 INT137504 Positive_regulation of Positive_regulation of Cdkn1b 2 0.45 1.71 0.45
125 INT163829 Positive_regulation of Localization of Cdkn1b 2 0.17 0.96 0.45
126 INT301056 Transcription of Mapk8 1 0.06 1.22 0.45
127 INT230265 Binding of Cav3 2 0.42 0.74 0.44
128 INT220504 Positive_regulation of Gene_expression of Cav1 11 0.39 6.26 0.43
129 INT166240 Regulation of Gene_expression of Cav1 3 0.51 1.03 0.43
130 INT152151 Regulation of Gene_expression of Apc 4 0.44 3.87 0.42
131 INT199262 Negative_regulation of Localization of Mapt 3 0.41 1.19 0.4
132 INT168952 Positive_regulation of Gene_expression of CAV3 1 0.49 0 0.4
133 INT187209 Negative_regulation of Localization of Mapk8 1 0.22 0.93 0.39
134 INT220506 Binding of Cav1 13 0.45 5.46 0.38
135 INT135953 Negative_regulation of Positive_regulation of Cav1 2 0.37 1.09 0.37
136 INT323313 Transcription of MAPT 1 0.69 0.45 0.37
137 INT263689 Positive_regulation of Mapt 6 0.49 5.15 0.36
138 INT199261 Negative_regulation of Gene_expression of Mapt 1 0.06 1.25 0.36
139 INT301047 Negative_regulation of Transcription of Mapk8 1 0.12 0.65 0.36
140 INT163277 Negative_regulation of Gene_expression of CAV1 17 0.56 10.77 0.35
141 INT107340 Negative_regulation of Phosphorylation of MAPT 3 0.57 2.64 0.35
142 INT89619 Phosphorylation of Map1b 2 0.54 1.06 0.35
143 INT220170 Regulation of Positive_regulation of Apc 1 0.10 0.46 0.35
144 INT149904 Regulation of Gene_expression of Cav3 1 0.27 0.35 0.35
145 INT149906 Regulation of Localization of Cav3 1 0.61 0.41 0.35
146 INT199265 Positive_regulation of Gene_expression of Mapt 3 0.67 1.34 0.34
147 INT204065 Regulation of Gene_expression of Cdkn1b 1 0.06 3.49 0.34
148 INT118243 Transcription of APC 4 0.45 3.33 0.33
149 INT184605 Positive_regulation of Transcription of APC 2 0.19 2.39 0.33
150 INT129153 Phosphorylation of CDKN1B 2 0.61 1.41 0.33
151 INT225667 Transcription of Apc 3 0.52 3.73 0.32
152 INT195672 Localization of APC 7 0.74 3.76 0.3
153 INT199277 Regulation of Gene_expression of Mapt 1 0.08 1.12 0.3
154 INT141867 Positive_regulation of Transcription of Cav1 2 0.52 0.46 0.29
155 INT141868 Transcription of Cav1 2 0.54 1.48 0.29
156 INT141861 Negative_regulation of Binding of Cav1 1 0.44 0.4 0.29
157 INT291227 Protein_catabolism of Mapk8 1 0.64 0.26 0.26
158 INT145070 Regulation of MAPT 2 0.44 0.72 0.25
159 INT1475 Localization of CLIP1 1 0.06 0 0.24
160 INT178399 Regulation of Positive_regulation of Mapk8 4 0.44 3.4 0.23
161 INT179043 Negative_regulation of Cdkn1b 7 0.36 5.99 0.22
162 INT135956 Phosphorylation of Cav1 5 0.64 2.24 0.22
163 INT233869 Binding of CDKN1B 2 0.47 0.46 0.22
164 INT135954 Positive_regulation of Phosphorylation of Cav1 2 0.40 0.64 0.22
165 INT299366 Positive_regulation of Transcription of Mapk8 2 0.70 1.29 0.22
166 INT225666 Regulation of Transcription of Apc 1 0.29 0.33 0.22
167 INT141860 Regulation of Localization of Cav1 1 0.20 0.2 0.22
168 INT179889 Negative_regulation of CDKN1B 4 0.57 1.71 0.21
169 INT308636 Positive_regulation of Phosphorylation of MAPT 1 0.67 2.31 0.21
170 INT306296 Regulation of CDKN1B 1 0.19 0.46 0.21
171 INT173166 Negative_regulation of Binding of APC 3 0.40 3.01 0.19
172 INT207621 Regulation of Mtap1b 3 0.35 0.15 0.19
173 INT221535 Regulation of Fes 1 0.25 0.19 0.19
174 INT221549 Localization of Fes 1 0.70 0.66 0.19
175 INT221532 Positive_regulation of Fes 1 0.47 0.59 0.19
176 INT220497 Regulation of Gene_expression of Cav1 4 0.36 1.84 0.18
177 INT179044 Regulation of Cdkn1b 4 0.22 2.64 0.18
178 INT86697 Negative_regulation of Regulation of Cav1 1 0.41 0 0.18
179 INT57065 Negative_regulation of Positive_regulation of APC 3 0.22 2.43 0.17
180 INT131000 Positive_regulation of Positive_regulation of CAV1 1 0.49 0 0.17
181 INT344867 Protein_catabolism of Mapt 1 0.86 0.25 0.17
182 INT149276 Positive_regulation of Binding of MAPT 1 0.49 0.41 0.17
183 INT228603 Positive_regulation of Positive_regulation of Apc 1 0.24 0.24 0.17
184 INT171218 Gene_expression of Mtap1b 8 0.45 1.04 0.16
185 INT201689 Protein_catabolism of CDKN1B 3 0.96 0.7 0.16
186 INT145253 Negative_regulation of Cav1 9 0.46 3.02 0.15
187 INT163278 Regulation of Gene_expression of CAV1 5 0.45 4.36 0.14
188 INT257863 Positive_regulation of Protein_catabolism of Cdkn1b 1 0.45 0.43 0.14
189 INT257865 Negative_regulation of Protein_catabolism of Cdkn1b 1 0.42 0.43 0.14
190 INT271765 Regulation of Cav3 1 0.05 0 0.14
191 INT257858 Protein_catabolism of Cdkn1b 1 0.64 0.43 0.14
192 INT214975 Localization of Cav1 7 0.75 2.7 0.13
193 INT137827 Negative_regulation of Gene_expression of MAPT 2 0.57 1.39 0.13
194 INT250790 Negative_regulation of Localization of APC 2 0.13 2.3 0.13
195 INT250792 Positive_regulation of Localization of APC 1 0.15 0.48 0.13
196 INT179034 Binding of Cdkn1b 7 0.31 5.12 0.12
197 INT221571 Negative_regulation of Fes 1 0.55 0.56 0.12
198 INT221577 Negative_regulation of Phosphorylation of Fes 1 0.40 0.37 0.12
199 INT222016 Regulation of Negative_regulation of Mapk8 1 0.44 0.79 0.12
200 INT242140 Regulation of Localization of Apc 1 0.12 0.12 0.11
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