GO:0031117

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Name positive regulation of microtubule depolymerization
Categary Process
Go Slim No
Go Link GO:0031117
Unique Molecular Interactions 65
Total Molecular Interactions 107
Total Single Events 729
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of microtubule depolymerization. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of microtubule depolymerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT181493 TRPV4 Regulation of Gene_expression of NGF 1 0.24 0.7 1.07
2 INT263232 Prkcg Positive_regulation of Trpv4 1 0.12 1.1 1.02
3 INT263227 Positive_regulation of Prkcg Regulation of Trpv4 1 0.07 0.95 1
4 INT149386 Binding of Lyn and TRPV4 1 0.40 1.14 0.91
5 INT159688 Trpv4 Negative_regulation of Trpv3 1 0.31 0.41 0.76
6 INT159689 Trpv4 Negative_regulation of Trpv1 1 0.36 0.41 0.76
7 INT159687 Trpv4 Negative_regulation of Trpv2 1 0.32 0.41 0.76
8 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75
9 INT322128 Binding of Ca2 and Trpv4 1 0.03 1.1 0.75
10 INT241247 Binding of Pkd2 and Trpv4 1 0.54 1.22 0.52
11 INT263228 Prkcg Regulation of Trpv4 1 0.07 0.36 0.5
12 INT263235 Trpv4 Regulation of Trpv1 1 0.17 0.7 0.5
13 INT322131 Binding of Prkcg and Trpv4 1 0.04 0.75 0.46
14 INT279705 CALM3 Regulation of TRPV4 2 0.08 0 0.33
15 INT322133 Trpv4 Regulation of Ca2 1 0.04 0.16 0.33
16 INT221918 TRPV4 Positive_regulation of TRPM8 1 0.05 0 0.28
17 INT322132 Binding of Mbp and Trpv4 1 0.11 0.39 0.27
18 INT309751 Binding of CA2 and TRPV4 1 0.08 0 0.23
19 INT118435 HGF Positive_regulation of TRPV4 1 0.54 0.13 0.2
20 INT142227 Urb1 Regulation of Trpv4 1 0.02 0.1 0.17
21 INT142229 Trpa1 Regulation of Trpv4 1 0.15 0.1 0.17
22 INT137672 Baa1 Positive_regulation of Trpv4 1 0.17 0 0.11
23 INT28816 Binding of TRPV4 and MND1 1 0.27 0.52 0.1
24 INT165324 Binding of TRPV4 and Trpv4 1 0.11 0.66 0.1
25 INT309724 Regulation of Binding of TYRP1 and TRPV4 1 0.01 0 0.09
26 INT309754 Binding of TYRP1 and TRPV4 1 0.02 0 0.09
27 INT133661 Bdnf Regulation of Gene_expression of STMN2 1 0.14 0 0.09
28 INT309722 TRPV4 Positive_regulation of CA2 1 0.11 0 0.08
29 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07
30 INT196124 Trpm5 Negative_regulation of Trpv4 1 0.13 0.08 0.06
31 INT196134 Gopc Negative_regulation of Trpv4 1 0.07 0.08 0.06
32 INT196126 Gopc Negative_regulation of Gene_expression of Trpv4 1 0.15 0.08 0.06
33 INT309732 CALM3 Positive_regulation of Gene_expression of TRPV4 1 0.14 0 0.06
34 INT196131 Trpm7 Negative_regulation of Trpv4 1 0.14 0.08 0.06
35 INT196130 Trpm5 Negative_regulation of Gene_expression of Trpv4 1 0.30 0.08 0.06
36 INT196129 Trpm7 Negative_regulation of Gene_expression of Trpv4 1 0.32 0.08 0.06
37 INT322130 Trpv1 Positive_regulation of Positive_regulation of Trpv4 1 0.15 0.1 0.05
38 INT333034 Trpv4 Positive_regulation of Localization of Car2 1 0.06 0 0.05
39 INT169403 Binding of TRPV1 and Trpv4 1 0.23 0.94 0.05
40 INT133662 Bdnf Positive_regulation of Gene_expression of STMN2 1 0.20 0 0.05
41 INT333032 Binding of Trpv4 and Gopc 1 0.05 0 0.04
42 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03
43 INT333037 Binding of Agt and Trpv4 1 0.09 0 0.03
44 INT309744 Binding of GOPC and TRPV4 1 0.09 0 0
45 INT329946 Binding of Stmn2 and Trpc5 1 0.03 0.15 0
46 INT322126 Binding of Trpv4 and Fig4 1 0.02 0 0
47 INT333035 Positive_regulation of Binding of Agt and Trpv4 1 0.11 0 0
48 INT309745 Negative_regulation of Binding of CALM3 and TRPV4 1 0.12 0 0
49 INT333030 Binding of Itch and Trpv4 1 0.14 0 0
50 INT333046 Binding of Trpv4 and ITCH 1 0.39 0 0
51 INT333036 Trpv4 Positive_regulation of Gene_expression of Agt 1 0.12 0 0
52 INT261833 Binding of Add3 and Trpv4 1 0.00 0.12 0
53 INT261838 Lyn Regulation of Trpv4 1 0.03 0.19 0
54 INT169448 Binding of Prkce and Trpv4 1 0.04 0.08 0
55 INT162407 TNF Positive_regulation of Gene_expression of TRPV4 1 0.47 0.22 0
56 INT261840 Binding of Mtap7 and Trpv4 1 0.05 0.12 0
57 INT261843 Lyn Regulation of Regulation of Trpv4 1 0.03 0.19 0
58 INT309736 PACSIN3 Regulation of TRPV4 1 0.55 0 0
59 INT333044 Positive_regulation of Binding of AGTR1 and Trpv4 1 0.48 0 0
60 INT309728 TRPV4 Positive_regulation of CFP 1 0.10 0 0
61 INT164929 Binding of Calca and Trpv4 1 0.32 0 0
62 INT333038 Agt Positive_regulation of Positive_regulation of Trpv4 1 0.12 0 0
63 INT333043 Binding of AGTR1 and Trpv4 1 0.50 0 0
64 INT261837 Binding of Aqp5 and Trpv4 1 0.05 0.17 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of microtubule depolymerization. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of microtubule depolymerization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109820 Gene_expression of Trpv4 121 0.78 39.69 33.11
2 INT112174 Gene_expression of Trpv4 47 0.78 26.26 20.09
3 INT119233 Positive_regulation of Trpv4 65 0.70 20.21 17.3
4 INT124702 Positive_regulation of Trpv4 21 0.69 7.14 8.2
5 INT124881 Binding of Trpv4 35 0.47 7.71 6.24
6 INT149385 Positive_regulation of TRPV4 11 0.69 7.22 6.02
7 INT118440 Gene_expression of TRPV4 20 0.71 7.33 6.01
8 INT156296 Regulation of Trpv4 20 0.45 7.84 4.86
9 INT109821 Negative_regulation of Trpv4 19 0.55 6.86 3.98
10 INT181496 Regulation of TRPV4 3 0.23 3.32 3.23
11 INT112175 Negative_regulation of Gene_expression of Trpv4 8 0.59 3.7 3.12
12 INT168744 Negative_regulation of Regulation of Trpv4 1 0.42 3.26 2.87
13 INT169402 Binding of Trpv4 8 0.47 5.13 2.78
14 INT115852 Transcription of Trpv4 9 0.71 2.23 2.65
15 INT28817 Binding of TRPV4 6 0.39 3.92 2.59
16 INT109822 Negative_regulation of Gene_expression of Trpv4 8 0.55 1.98 2.53
17 INT115199 Localization of Trpv4 12 0.79 3.65 2.5
18 INT159809 Localization of Trpv4 6 0.78 3.67 2.46
19 INT156301 Regulation of Trpv4 11 0.60 2.81 2.35
20 INT156299 Phosphorylation of Trpv4 8 0.80 2.46 2.31
21 INT137670 Positive_regulation of Gene_expression of Trpv4 12 0.68 3.42 1.77
22 INT149153 Positive_regulation of Gene_expression of Trpv4 12 0.70 3.37 1.72
23 INT149152 Negative_regulation of Trpv4 5 0.58 1.8 1.52
24 INT89983 Gene_expression of STMN2 8 0.72 0 1.42
25 INT149384 Negative_regulation of TRPV4 4 0.43 2.41 1.23
26 INT326452 Gene_expression of Stmn2 1 0.55 0.65 1.11
27 INT181497 Regulation of Regulation of TRPV4 1 0.23 0.69 1.08
28 INT261816 Positive_regulation of Localization of Trpv4 2 0.47 1.16 1.07
29 INT156175 Positive_regulation of Positive_regulation of Trpv4 5 0.50 0.86 0.8
30 INT158547 Negative_regulation of Positive_regulation of Trpv4 2 0.57 0.47 0.77
31 INT263225 Positive_regulation of Positive_regulation of Trpv4 3 0.46 0.75 0.7
32 INT156302 Positive_regulation of Phosphorylation of Trpv4 2 0.46 0.92 0.68
33 INT89985 Transcription of STMN2 5 0.50 0 0.64
34 INT156303 Regulation of Regulation of Trpv4 2 0.27 0.26 0.63
35 INT158548 Regulation of Gene_expression of Trpv4 3 0.61 1.03 0.57
36 INT125188 Negative_regulation of Transcription of Trpv4 3 0.42 0.44 0.56
37 INT263224 Phosphorylation of Trpv4 2 0.76 0.73 0.49
38 INT137671 Negative_regulation of Positive_regulation of Trpv4 3 0.58 0.25 0.48
39 INT212307 Regulation of Gene_expression of Trpv4 8 0.44 2.85 0.39
40 INT89984 Regulation of Gene_expression of STMN2 1 0.57 0 0.26
41 INT118446 Positive_regulation of Transcription of TRPV4 1 0.49 0.26 0.21
42 INT118447 Transcription of TRPV4 1 0.67 0.26 0.21
43 INT156172 Transcription of Trpv4 3 0.72 1.19 0.19
44 INT133659 Positive_regulation of Gene_expression of STMN2 1 0.65 0 0.19
45 INT209259 Regulation of Gene_expression of TRPV4 1 0.22 0.93 0.19
46 INT89982 Regulation of Transcription of STMN2 1 0.02 0 0.18
47 INT322153 Positive_regulation of Binding of Trpv4 1 0.49 0 0.18
48 INT162409 Positive_regulation of Gene_expression of TRPV4 2 0.45 0 0.16
49 INT333015 Regulation of Binding of Trpv4 1 0.42 0.43 0.13
50 INT200259 Negative_regulation of Negative_regulation of Stmn2 1 0.11 0.45 0.11
51 INT200253 Negative_regulation of Stmn2 1 0.16 0.45 0.11
52 INT133658 Negative_regulation of Gene_expression of STMN2 1 0.40 0 0.1
53 INT133657 Negative_regulation of Transcription of STMN2 1 0.40 0 0.1
54 INT156173 Positive_regulation of Transcription of Trpv4 1 0.61 0.43 0.1
55 INT133660 Positive_regulation of STMN2 1 0.56 0 0.09
56 INT309764 Regulation of Binding of TRPV4 1 0.36 0 0.08
57 INT333013 Positive_regulation of Protein_catabolism of Trpv4 1 0.43 0 0
58 INT333010 Positive_regulation of Binding of Trpv4 1 0.47 0 0
59 INT158549 Negative_regulation of Transcription of Trpv4 1 0.42 0 0
60 INT156298 Negative_regulation of Phosphorylation of Trpv4 1 0.43 0.14 0
61 INT322151 Positive_regulation of Localization of Trpv4 1 0.49 0.31 0
62 INT333022 Positive_regulation of Phosphorylation of Trpv4 1 0.47 0 0
63 INT333018 Positive_regulation of Negative_regulation of Trpv4 1 0.43 0 0
64 INT333016 Protein_catabolism of Trpv4 1 0.93 0 0
65 INT333026 Regulation of Localization of Trpv4 1 0.42 0 0
66 INT309763 Localization of TRPV4 1 0.60 0 0
67 INT333027 Negative_regulation of Binding of Trpv4 1 0.40 0 0
68 INT158546 Regulation of Transcription of Trpv4 1 0.45 0.17 0
69 INT333017 Negative_regulation of Localization of Trpv4 1 0.40 0 0
70 INT309758 Negative_regulation of Gene_expression of TRPV4 1 0.34 0 0
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