GO:0031227

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Name intrinsic to endoplasmic reticulum membrane
Categary Component
Go Slim No
Go Link GO:0031227
Unique Molecular Interactions 44
Total Molecular Interactions 62
Total Single Events 490
Pain Genes Associated 7

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for intrinsic to endoplasmic reticulum membrane. They are ordered first by their pain relevance and then by number of times they were reported for intrinsic to endoplasmic reticulum membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT349583 Aap Positive_regulation of Gene_expression of Cyp2e1 1 0.18 1.57 3.59
2 INT349584 Binding of Cyp2e1 and Aap 1 0.10 1.56 3.24
3 INT349589 Aap Positive_regulation of Cyp2e1 1 0.21 1.84 2.71
4 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98
5 INT77083 Das Negative_regulation of Cyp2e1 1 0.20 0.59 1.06
6 INT53750 Cyp2e1 Positive_regulation of RYBP 1 0.14 0.44 0.99
7 INT90385 EXTL3 Regulation of Ctsl 1 0.00 1.1 0.98
8 INT56274 RYBP Negative_regulation of Cyp2e1 1 0.01 0.17 0.9
9 INT56272 Cyp2e1 Positive_regulation of Cyp1a2 1 0.52 0.17 0.77
10 INT76026 Binding of Cyp2e1 and Cyp3a11 1 0.28 0.42 0.64
11 INT149929 Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.12 0 0.61
12 INT102670 Cyp2e1 Regulation of RYBP 1 0.01 0 0.58
13 INT102666 Cyp2e1 Regulation of Cyp1a2 1 0.20 0 0.58
14 INT326473 Positive_regulation of PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.41
15 INT326470 PGAP1 Positive_regulation of ROS1 1 0.00 0.07 0.4
16 INT326472 AGXT Negative_regulation of PGAP1 1 0.00 0.05 0.39
17 INT296473 Prkca Regulation of Serac1 1 0.00 0.14 0.3
18 INT100823 Cyp2e1 Positive_regulation of Ros1 1 0.35 1.22 0.22
19 INT20310 Binding of Hnf1a and Positive_regulation of Transcription of Cyp2e1 1 0.02 0 0.21
20 INT125550 FGFR1 Negative_regulation of Cyp2e1 1 0.02 0.06 0.18
21 INT301615 Binding of Cyp2e1 and Samsn1 1 0.02 2.42 0.18
22 INT125551 Binding of FGFR1 and Cyp2e1 1 0.02 0.07 0.13
23 INT264103 Cyp2e1 Regulation of CYP2C9 1 0.04 0 0.09
24 INT264107 Cyp2e1 Regulation of CYP2D6 1 0.05 0 0.09
25 INT264105 Cyp2e1 Regulation of CYP3A4 1 0.02 0 0.09
26 INT57965 Myo5a Negative_regulation of Cyp2e1 1 0.01 0.09 0.07
27 INT168368 Binding of Cyp1a2 and Cyp2e1 1 0.37 0.08 0.07
28 INT342221 Cyp2e1 Positive_regulation of Gene_expression of TRNAI1 1 0.03 0.22 0.05
29 INT125643 Cyp2e1 Positive_regulation of Transcription of Cyp2c11 1 0.51 0 0
30 INT125656 Cyp2e1 Positive_regulation of Transcription of Cyp2b2 1 0.07 0 0
31 INT336134 Binding of EXTL3 and ATP6AP2 1 0.00 0.37 0
32 INT301640 Positive_regulation of Cyp2e1 Positive_regulation of Gene_expression of Ros1 1 0.03 0.25 0
33 INT125646 Cyp2b2 Positive_regulation of Transcription of Cyp2e1 1 0.07 0 0
34 INT209630 ALG12 Regulation of Gene_expression of AR 1 0.13 0.38 0
35 INT209635 AR Positive_regulation of ALG12 1 0.14 0.32 0
36 INT336129 Binding of ANG and EXTL3 1 0.01 0.38 0
37 INT125652 Cyp2c6 Positive_regulation of Transcription of Cyp2e1 1 0.49 0 0
38 INT125650 Cyp2e1 Positive_regulation of Transcription of Cyp2c6 1 0.49 0 0
39 INT125661 Cyp2c11 Positive_regulation of Transcription of Cyp2e1 1 0.51 0 0
40 INT199711 2610029G23Rik Regulation of Cyp2e1 1 0.03 0.45 0
41 INT336133 Binding of EXTL3 and REN 1 0.03 0.37 0
42 INT125654 Cyp2e1 Positive_regulation of Transcription of Cyp3a23/3a1 1 0.43 0 0
43 INT278383 Pigb Regulation of Il1 1 0.00 0.2 0
44 INT278409 Pigb Regulation of Hps5 1 0.00 0.2 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for intrinsic to endoplasmic reticulum membrane. They are ordered first by their pain relevance and then by number of times they were reported in intrinsic to endoplasmic reticulum membrane. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT20307 Positive_regulation of Cyp2e1 70 0.70 23.59 32.49
2 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72
3 INT20305 Gene_expression of Cyp2e1 53 0.78 19.75 19.54
4 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39
5 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08
6 INT53746 Regulation of Cyp2e1 11 0.62 3.82 9.52
7 INT57665 Negative_regulation of Cyp2e1 35 0.59 8.05 9.29
8 INT107087 Positive_regulation of Gene_expression of Cyp2e1 20 0.70 8.89 9.04
9 INT142694 Positive_regulation of PGAP1 3 0.08 2.78 8.68
10 INT62579 Negative_regulation of Gene_expression of Cyp2e1 8 0.59 2.95 5.48
11 INT322474 Regulation of PGAP1 1 0.38 4.82 5.06
12 INT322475 Negative_regulation of PGAP1 9 0.36 4.78 4.69
13 INT52088 Binding of Cyp2e1 8 0.48 2.5 4.43
14 INT100262 Positive_regulation of Positive_regulation of Cyp2e1 7 0.50 2.39 4.31
15 INT20303 Regulation of Cyp2e1 11 0.61 2.46 3.84
16 INT79096 Binding of Cyp2e1 12 0.48 4.41 3.8
17 INT52084 Localization of Cyp2e1 6 0.71 1.99 2.79
18 INT20304 Transcription of Cyp2e1 11 0.70 2.5 2.57
19 INT107091 Regulation of Gene_expression of Cyp2e1 4 0.62 2.17 2.03
20 INT82722 Negative_regulation of Positive_regulation of Cyp2e1 6 0.59 3.74 2.02
21 INT53387 Negative_regulation of Positive_regulation of Cyp2e1 3 0.42 1.28 1.98
22 INT82649 Negative_regulation of Gene_expression of Cyp2e1 3 0.58 2.51 1.93
23 INT296432 Phosphorylation of Serac1 5 0.02 1.46 1.52
24 INT115374 Positive_regulation of Gene_expression of Cyp2e1 6 0.67 4.36 1.27
25 INT123284 Positive_regulation of Positive_regulation of Cyp2e1 3 0.46 2.34 1.22
26 INT132623 Transcription of Cyp2e1 2 0.53 0.56 0.98
27 INT56270 Negative_regulation of Binding of Cyp2e1 1 0.42 0.17 0.94
28 INT56271 Positive_regulation of Negative_regulation of Cyp2e1 1 0.46 0.17 0.93
29 INT326487 Positive_regulation of Positive_regulation of PGAP1 1 0.01 0.07 0.8
30 INT149926 Negative_regulation of Negative_regulation of Cyp2e1 1 0.43 0.14 0.78
31 INT149927 Regulation of Negative_regulation of Cyp2e1 1 0.45 0.13 0.78
32 INT98177 Negative_regulation of Transcription of Cyp2e1 2 0.40 0.89 0.75
33 INT20306 Positive_regulation of Transcription of Cyp2e1 2 0.49 0.63 0.73
34 INT168367 Localization of Cyp2e1 2 0.71 0.6 0.72
35 INT197781 Binding of Serac1 1 0.01 0.36 0.7
36 INT79097 Positive_regulation of Binding of Cyp2e1 1 0.50 0.53 0.69
37 INT149928 Positive_regulation of Negative_regulation of Cyp2e1 2 0.50 0.35 0.68
38 INT163991 Positive_regulation of Regulation of Cyp2e1 1 0.70 0.28 0.52
39 INT163994 Positive_regulation of Binding of Cyp2e1 2 0.50 0.45 0.5
40 INT326485 Negative_regulation of Positive_regulation of PGAP1 1 0.01 0.08 0.49
41 INT92197 Gene_expression of PGAP1 1 0.00 0.3 0.4
42 INT322476 Positive_regulation of Negative_regulation of PGAP1 1 0.29 0.46 0.28
43 INT174652 Gene_expression of EXTL3 2 0.05 1.49 0.15
44 INT137620 Protein_catabolism of Cyp2e1 1 0.16 0 0.11
45 INT168366 Positive_regulation of Localization of Cyp2e1 1 0.48 0.05 0.09
46 INT152879 Regulation of Negative_regulation of Cyp2e1 1 0.45 0.8 0.08
47 INT278337 Positive_regulation of Pigb 1 0.01 0.27 0.08
48 INT342207 Regulation of Gene_expression of Cyp2e1 1 0.25 0.51 0.03
49 INT336138 Negative_regulation of Gene_expression of EXTL3 1 0.04 0.2 0.03
50 INT209680 Positive_regulation of ALG12 1 0.16 0.37 0
51 INT35638 Localization of PGAP1 1 0.01 0.69 0
52 INT310441 Regulation of EXTL3 1 0.26 0.97 0
53 INT209659 Gene_expression of ALG12 1 0.21 0.89 0
54 INT132624 Negative_regulation of Transcription of Cyp2e1 1 0.40 0.06 0
55 INT336139 Binding of EXTL3 1 0.05 0.67 0
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