GO:0031325

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Name positive regulation of cellular metabolic process
Categary Process
Go Slim No
Go Link GO:0031325
Unique Molecular Interactions 48
Total Molecular Interactions 63
Total Single Events 368
Pain Genes Associated 8

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cellular metabolic process. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of cellular metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
2 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
3 INT75937 MLXIPL Regulation of Csf2 1 0.01 0.68 0.74
4 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
5 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
6 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
7 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
8 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
9 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
10 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
11 INT242094 Binding of ACLY and Pts 1 0.01 0 0.22
12 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
13 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
14 INT40819 Binding of ADRB3 and AGPAT1 1 0.24 0 0.18
15 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
16 INT194576 Binding of ACLY and CD40LG 1 0.07 0.07 0.14
17 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
18 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
19 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
20 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
21 INT190246 TARBP2 Positive_regulation of PKLR 1 0.01 0.41 0.1
22 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
23 INT279417 Binding of PPARA and MLXIPL 3 0.00 0.33 0.07
24 INT279421 Binding of NR1H4 and MLXIPL 1 0.00 0.27 0.07
25 INT279413 Binding of RARB and MLXIPL 1 0.00 0.27 0.07
26 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
27 INT145622 Binding of PKLR and UGT1A3 1 0.01 0 0.06
28 INT145623 Binding of PKLR and UGT2B4 1 0.02 0 0.06
29 INT145626 Binding of PKLR and UGT1A1 1 0.02 0 0.06
30 INT145621 Binding of PKLR and UGT2B7 1 0.02 0 0.06
31 INT145624 Binding of PKLR and UGT1A9 1 0.02 0 0.06
32 INT353912 Binding of ACLY and LARS 1 0.25 0.28 0.06
33 INT145625 Binding of PKLR and UGT2B17 1 0.01 0 0.06
34 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
35 INT190247 TARBP2 Negative_regulation of PKLR 1 0.01 0.2 0.05
36 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
37 INT225562 Binding of Srcs4 and Ep300 1 0.02 0 0
38 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
39 INT172604 Binding of EP300 and TP53 1 0.00 0 0
40 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
41 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
42 INT225619 Binding of TARBP2 and Ep300 1 0.02 0 0
43 INT172605 Positive_regulation of Binding of EP300 and TP53 1 0.00 0 0
44 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0
45 INT225543 Binding of D0Nrs1 and Ep300 1 0.01 0 0
46 INT225563 Binding of Tpr and Ep300 1 0.00 0 0
47 INT295616 ACACB Regulation of INS 1 0.02 0.6 0
48 INT225622 Binding of STL and Ep300 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of cellular metabolic process. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of cellular metabolic process. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54
2 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
3 INT35584 Binding of ACLY 22 0.35 31.78 7.17
4 INT2213 Regulation of EP300 10 0.54 4.72 4.5
5 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
6 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12
7 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
8 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
9 INT171514 Binding of EP300 13 0.32 4.32 2.01
10 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
11 INT172622 Localization of EP300 8 0.65 2.56 1.72
12 INT75935 Regulation of MLXIPL 4 0.18 3.82 1.7
13 INT181868 Localization of ACLY 5 0.62 6.36 1.4
14 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
15 INT60286 Gene_expression of PKLR 5 0.65 2.14 1.04
16 INT167650 Binding of Ep300 1 0.09 0.14 1
17 INT120408 Localization of PKLR 1 0.01 0.8 0.99
18 INT69132 Negative_regulation of ACLY 5 0.42 2.95 0.92
19 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
20 INT157073 Positive_regulation of PKLR 6 0.36 5.48 0.69
21 INT60289 Negative_regulation of PKLR 5 0.21 1.75 0.53
22 INT120399 Positive_regulation of Phosphorylation of PKLR 1 0.01 0.44 0.53
23 INT120389 Phosphorylation of PKLR 2 0.11 1.81 0.51
24 INT40820 Binding of AGPAT1 1 0.32 0 0.51
25 INT316558 Positive_regulation of ACACB 1 0.21 2.66 0.42
26 INT119001 Regulation of ACLY 5 0.44 4.83 0.36
27 INT60287 Regulation of PKLR 1 0.15 0.32 0.35
28 INT187587 Binding of Ep300 11 0.35 2.37 0.34
29 INT316557 Regulation of ACACB 1 0.14 3.3 0.29
30 INT60288 Regulation of Gene_expression of PKLR 1 0.15 0.32 0.28
31 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
32 INT125877 Binding of PKLR 2 0.04 0.26 0.22
33 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
34 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
35 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
36 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
37 INT40821 Negative_regulation of Binding of AGPAT1 1 0.39 0 0.18
38 INT318985 Positive_regulation of Positive_regulation of ACLY 1 0.08 1.77 0.15
39 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
40 INT259037 Negative_regulation of Binding of ACLY 1 0.07 1.54 0.13
41 INT295619 Localization of ACACB 2 0.65 1.79 0.11
42 INT273675 Binding of ACACB 7 0.42 8.69 0.09
43 INT259039 Positive_regulation of Binding of ACLY 1 0.09 1.85 0.09
44 INT259030 Negative_regulation of Gene_expression of ACLY 1 0.07 1.95 0.08
45 INT344278 Positive_regulation of Localization of ACLY 1 0.08 1.16 0.08
46 INT292252 Phosphorylation of EP300 1 0.20 0.55 0.05
47 INT230012 Protein_catabolism of ACLY 1 0.37 0.27 0.03
48 INT273677 Gene_expression of ACACB 15 0.67 9.36 0
49 INT181272 Positive_regulation of Gene_expression of ACLY 3 0.44 1.29 0
50 INT235154 Transcription of Ep300 2 0.24 1.38 0
51 INT82996 Transcription of PKLR 2 0.51 0.6 0
52 INT222914 Negative_regulation of Gene_expression of EP300 1 0.02 0.05 0
53 INT295618 Positive_regulation of Gene_expression of ACACB 1 0.43 0.68 0
54 INT330341 Positive_regulation of Gene_expression of PKLR 1 0.08 1.13 0
55 INT236412 Positive_regulation of Transcription of ACLY 1 0.44 0.4 0
56 INT319097 Negative_regulation of Transcription of PKLR 1 0.05 0.24 0
57 INT319098 Protein_catabolism of PKLR 1 0.13 0.49 0
58 INT236411 Transcription of ACLY 1 0.60 0.4 0
59 INT198781 Regulation of Gene_expression of ACLY 1 0.39 0 0
60 INT330349 Negative_regulation of Gene_expression of PKLR 1 0.07 1.23 0
61 INT222960 Gene_expression of MLXIPL 1 0.01 0 0
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