GO:0031369

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Name translation initiation factor binding
Categary Function
Go Slim No
Go Link GO:0031369
Unique Molecular Interactions 53
Total Molecular Interactions 81
Total Single Events 513
Pain Genes Associated 4

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for translation initiation factor binding. They are ordered first by their pain relevance and then by number of times they were reported for translation initiation factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
2 INT341214 Tas2r130 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.00 0.68 0.31
3 INT277317 Binding of Celf1 and Slc6a11 1 0.19 0.06 0.26
4 INT273902 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.56 0.15
5 INT311399 Binding of Celf1 and Uts2r 1 0.08 0.26 0.12
6 INT341235 Negative_regulation of INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.24 0.09
7 INT277319 Gene_expression of Celf1 Positive_regulation of Positive_regulation of Slc6a11 1 0.24 0.08 0.08
8 INT341220 Eif4e Positive_regulation of Eif4ebp1 1 0.20 0.42 0.06
9 INT341219 Binding of Eif4ebp1 and Eif4g3 1 0.05 0 0.06
10 INT257869 Rps6kb1 Regulation of Eif4ebp1 1 0.02 0.64 0.04
11 INT341231 INS Positive_regulation of Phosphorylation of Eif4ebp1 1 0.01 0.13 0.04
12 INT257872 Eif4ebp1 Regulation of Rps6kb1 1 0.02 0.64 0.04
13 INT341236 ROS1 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.02 0.25 0.04
14 INT253374 Lep Positive_regulation of Phosphorylation of Eif4ebp1 1 0.04 0.16 0.03
15 INT341225 Negative_regulation of Binding of Eif4e and Eif4ebp1 1 0.17 0.14 0.03
16 INT253416 ATIC Negative_regulation of Phosphorylation of Eif4ebp1 1 0.00 0 0.03
17 INT253411 ATIC Negative_regulation of Eif4ebp1 1 0.00 0 0.03
18 INT272517 Binding of Ccnd1 and Celf1 3 0.08 0.07 0
19 INT272516 Binding of Celf1 and Tpt1 2 0.05 0.07 0
20 INT311390 Mbnl1 Positive_regulation of Celf1 1 0.26 0.48 0
21 INT311387 Binding of Celf1 and Mbnl1 1 0.20 0.25 0
22 INT311405 CCND3 Regulation of Celf1 1 0.41 0.14 0
23 INT150051 Mtor Positive_regulation of Eif4ebp1 1 0.50 0.46 0
24 INT311404 Binding of CDKN2A and Celf1 1 0.32 0.07 0
25 INT272518 Positive_regulation of Binding of Ccnd1 and Celf1 1 0.01 0 0
26 INT311389 Positive_regulation of Binding of Celf1 and Eif2s2 1 0.17 0.59 0
27 INT272522 Celf1 Positive_regulation of Phosphorylation of CEBPD 1 0.03 0.52 0
28 INT311381 Phosphorylation of Akt1 Regulation of Celf1 1 0.10 0.14 0
29 INT341240 Binding of EIF4E and Eif4ebp1 1 0.04 0.5 0
30 INT311379 Celf1 Negative_regulation of Mbnl1 1 0.24 0.26 0
31 INT311398 Positive_regulation of Celf1 Positive_regulation of Hdac1 1 0.12 0.19 0
32 INT311385 Gopc Regulation of Celf1 1 0.04 0.14 0
33 INT311380 Positive_regulation of Celf1 Negative_regulation of Mbnl1 1 0.26 0.26 0
34 INT311397 Binding of Celf1 and Gopc 1 0.04 0.09 0
35 INT341221 Eif4e Regulation of Binding of Eif4ebp1 1 0.18 0 0
36 INT341227 Mtor Regulation of Phosphorylation of Eif4ebp1 1 0.02 0.19 0
37 INT311375 Phosphorylation of Prkca Positive_regulation of Celf1 1 0.04 0.1 0
38 INT341216 Regulation of Binding of Eif4e and Eif4ebp1 1 0.11 0 0
39 INT253360 Lep Positive_regulation of Eif4ebp1 1 0.01 0.08 0
40 INT272515 Akt1 Positive_regulation of Binding of Celf1 1 0.03 0 0
41 INT352841 Binding of Miox and Lin28a 1 0.00 0 0
42 INT150049 Ins1 Positive_regulation of Eif4ebp1 1 0.24 0.46 0
43 INT311394 Binding of Celf1 and Eif2s2 1 0.12 1.67 0
44 INT311391 Binding of Celf1 and Dmpk 1 0.34 0.09 0
45 INT277308 Upf1 Regulation of Regulation of Celf1 1 0.00 1.05 0
46 INT311376 Binding of Ccnd3 and Celf1 1 0.06 0.07 0
47 INT341233 Positive_regulation of Binding of EIF4E and Eif4ebp1 1 0.06 0.5 0
48 INT311386 Celf1 Regulation of Insr 1 0.00 0.24 0
49 INT352842 Binding of Lin28a and Mirlet7a-1 1 0.03 0 0
50 INT311388 Mbnl1 Positive_regulation of Binding of Celf1 1 0.26 0.13 0
51 INT311396 Akt1 Regulation of Celf1 1 0.04 0.14 0
52 INT277314 Celf1 Regulation of Gene_expression of Slc6a11 1 0.23 0.06 0
53 INT311403 CDKN2A Regulation of Celf1 1 0.41 0.14 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for translation initiation factor binding. They are ordered first by their pain relevance and then by number of times they were reported in translation initiation factor binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT228659 Phosphorylation of Eif4ebp1 10 0.80 27.53 6.87
2 INT77226 Phosphorylation of Eif4ebp1 36 0.09 6.39 2.91
3 INT77227 Positive_regulation of Phosphorylation of Eif4ebp1 11 0.05 2.44 1.67
4 INT228661 Negative_regulation of Phosphorylation of Eif4ebp1 6 0.41 2.25 1.16
5 INT77224 Negative_regulation of Phosphorylation of Eif4ebp1 7 0.05 0.7 1.04
6 INT341181 Positive_regulation of Phosphorylation of Eif4ebp1 1 0.30 4.99 0.86
7 INT255101 Positive_regulation of Celf1 23 0.56 11.91 0.84
8 INT341172 Regulation of Eif4ebp1 1 0.20 4.42 0.74
9 INT77223 Regulation of Eif4ebp1 6 0.03 1.32 0.7
10 INT255120 Gene_expression of Celf1 29 0.62 10.82 0.59
11 INT272471 Binding of Celf1 5 0.39 4.97 0.56
12 INT277278 Regulation of Celf1 4 0.49 4.63 0.48
13 INT341203 Binding of Eif4ebp1 1 0.21 0.86 0.46
14 INT255135 Positive_regulation of Gene_expression of Celf1 18 0.56 5.84 0.43
15 INT77225 Binding of Eif4ebp1 1 0.00 0.07 0.42
16 INT308847 Regulation of Phosphorylation of Eif4ebp1 3 0.27 2.11 0.41
17 INT228660 Negative_regulation of Eif4ebp1 2 0.41 1.19 0.32
18 INT87042 Regulation of Phosphorylation of Eif4ebp1 1 0.00 0.26 0.27
19 INT228662 Gene_expression of Eif4ebp1 2 0.65 0.91 0.26
20 INT277269 Positive_regulation of Binding of Celf1 2 0.40 0.89 0.24
21 INT316448 Positive_regulation of Lin28a 1 0.26 0.53 0.24
22 INT341187 Regulation of Binding of Eif4ebp1 1 0.12 0.19 0.17
23 INT255125 Localization of Celf1 7 0.60 2.84 0.11
24 INT253386 Gene_expression of Eif4ebp1 5 0.07 1.37 0.11
25 INT341199 Negative_regulation of Gene_expression of Eif4ebp1 1 0.19 0.18 0.09
26 INT341193 Positive_regulation of Gene_expression of Eif4ebp1 1 0.22 0.17 0.09
27 INT272486 Phosphorylation of Celf1 10 0.66 4.63 0.08
28 INT87043 Positive_regulation of Eif4ebp1 3 0.06 0.26 0.07
29 INT341171 Positive_regulation of Eif4ebp1 1 0.22 0.48 0.07
30 INT255119 Positive_regulation of Positive_regulation of Celf1 3 0.40 1.26 0.05
31 INT272467 Positive_regulation of Phosphorylation of Celf1 3 0.56 1.61 0.05
32 INT341196 Positive_regulation of Localization of Eif4ebp1 1 0.30 0.26 0.05
33 INT311331 Negative_regulation of Binding of Celf1 1 0.34 0 0.04
34 INT253396 Negative_regulation of Eif4ebp1 3 0.05 0 0.03
35 INT281602 Negative_regulation of Localization of Eif4ebp1 1 0.05 0 0.03
36 INT87041 Regulation of Positive_regulation of Eif4ebp1 1 0.01 0.26 0.03
37 INT341207 Localization of Eif4ebp1 1 0.35 0.13 0.03
38 INT281606 Localization of Eif4ebp1 1 0.09 0 0.03
39 INT341201 Negative_regulation of Binding of Eif4ebp1 1 0.19 0.23 0.03
40 INT272478 Regulation of Phosphorylation of Celf1 2 0.49 0.36 0
41 INT255108 Regulation of Gene_expression of Celf1 2 0.36 0.18 0
42 INT272459 Negative_regulation of Phosphorylation of Celf1 2 0.47 0.55 0
43 INT311306 Regulation of Transcription of Celf1 1 0.22 0.29 0
44 INT253399 Negative_regulation of Gene_expression of Eif4ebp1 1 0.03 0 0
45 INT311310 Regulation of Binding of Celf1 1 0.36 0.88 0
46 INT311340 Positive_regulation of Transcription of Celf1 1 0.40 0.08 0
47 INT255114 Negative_regulation of Celf1 1 0.07 0.29 0
48 INT352833 Binding of Lin28a 1 0.19 0.54 0
49 INT255105 Negative_regulation of Gene_expression of Celf1 1 0.05 0.21 0
50 INT311302 Positive_regulation of Protein_catabolism of Celf1 1 0.40 0.13 0
51 INT311322 Transcription of Celf1 1 0.55 0.38 0
52 INT311327 Protein_catabolism of Celf1 1 0.71 0.13 0
53 INT311330 Negative_regulation of Positive_regulation of Celf1 1 0.35 0.85 0
54 INT311315 Regulation of Positive_regulation of Celf1 1 0.22 0.29 0
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