GO:0031396

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Name regulation of protein ubiquitination
Categary Process
Go Slim No
Go Link GO:0031396
Unique Molecular Interactions 115
Total Molecular Interactions 142
Total Single Events 658
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for regulation of protein ubiquitination. They are ordered first by their pain relevance and then by number of times they were reported for regulation of protein ubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT321474 Binding of Slc6a2 and Ubqln1 1 0.00 0.8 2.27
2 INT321477 Binding of Ubqln1 and Flvcr2 1 0.00 0.81 2.26
3 INT321475 Slc6a2 Positive_regulation of Ubqln1 1 0.00 0.38 1.19
4 INT139188 Binding of Daxx and Fas 1 0.03 0.55 1.14
5 INT321473 Binding of Slc6a3 and Ubqln1 1 0.00 0.41 1.13
6 INT139752 Ubqln1 Regulation of Localization of Prl 1 0.05 0 1.04
7 INT75486 Binding of Tgfbr1 and Tgfbr2 1 0.10 1.94 1.02
8 INT133614 Map2k1 Regulation of Daxx 1 0.02 0.29 0.97
9 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85
10 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85
11 INT16436 Ubqln1 Regulation of Localization of Avp 1 0.01 0 0.81
12 INT16435 Ubqln1 Regulation of Localization of Lnpep 1 0.01 0 0.81
13 INT161951 Positive_regulation of TGFBR1 Positive_regulation of Gene_expression of Ngf 1 0.27 0.99 0.76
14 INT161945 TGFB2 Positive_regulation of TGFBR1 1 0.08 0.99 0.76
15 INT161950 TGFBR1 Negative_regulation of Localization of Ngf 1 0.23 1.01 0.72
16 INT16437 Ubqln1 Positive_regulation of Localization of Oxt 1 0.03 0 0.7
17 INT214368 Pik3cb Regulation of Ubqln1 1 0.01 0.36 0.68
18 INT321479 Ubqln1 Regulation of Cfp 1 0.00 0.37 0.67
19 INT244043 Binding of Gabrg1 and Ubqln1 1 0.03 0.26 0.59
20 INT139189 Binding of Daxx and Fadd 1 0.03 0.27 0.57
21 INT5631 Ubqln1 Positive_regulation of Pdpk1 1 0.05 0 0.53
22 INT139750 Ubqln1 Regulation of Dbh 1 0.00 0 0.52
23 INT302644 ARSA Positive_regulation of Gene_expression of TGFBR1 1 0.04 0.29 0.51
24 INT302647 ARSA Positive_regulation of TGFBR1 1 0.03 0.29 0.51
25 INT155086 CASP1 Negative_regulation of DAXX 1 0.21 1.26 0.45
26 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
27 INT112619 Mapk9 Regulation of Il1b 1 0.16 1.11 0.36
28 INT112620 Mapk9 Regulation of Tnf 1 0.16 1.11 0.36
29 INT214371 Amph Positive_regulation of Ubqln1 1 0.01 0 0.3
30 INT214373 Negative_regulation of Amph Positive_regulation of Ubqln1 1 0.01 0 0.3
31 INT244034 Binding of Gabrg2 and Ubqln1 1 0.01 0.09 0.26
32 INT311918 Insrr Negative_regulation of Tgfbr1 1 0.00 0.87 0.26
33 INT311902 Acvrl1 Negative_regulation of Tgfbr1 1 0.13 0.87 0.26
34 INT244064 Binding of Gabpb1 and Ubqln1 1 0.00 0.09 0.26
35 INT311911 Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.55 0.23
36 INT224431 TNF Positive_regulation of Gene_expression of FBXO2 1 0.47 0.35 0.22
37 INT224452 Il1 Positive_regulation of Gene_expression of FBXO2 1 0.37 0.35 0.22
38 INT214367 Amph Positive_regulation of Localization of Ubqln1 1 0.01 0 0.21
39 INT159794 Tnf Positive_regulation of Mapk9 1 0.01 0.42 0.19
40 INT159793 Tnf Positive_regulation of Gene_expression of Mapk9 1 0.01 0.42 0.19
41 INT214376 Ubqln1 Regulation of Flvcr2 1 0.00 0 0.19
42 INT214375 Amph Regulation of Ubqln1 1 0.00 0 0.16
43 INT147357 Mapk9 Positive_regulation of Htr5a 1 0.06 0.76 0.12
44 INT147362 Mapk9 Positive_regulation of Ddit3 1 0.57 0.76 0.12
45 INT147361 Mapk9 Positive_regulation of Tnfrsf10b 1 0.40 0.76 0.12
46 INT204996 Binding of Park7 and Pink1 2 0.34 1.09 0.11
47 INT204993 Eri1 Positive_regulation of Gene_expression of Pink1 1 0.22 0.61 0.08
48 INT311917 Gene_expression of Tgfbr1 Positive_regulation of Gene_expression of Mmp13 1 0.10 0.31 0.08
49 INT311915 Tgfbr1 Negative_regulation of Gene_expression of Mmp13 1 0.09 0.27 0.06
50 INT204999 Hmmr Positive_regulation of Pink1 1 0.01 0.58 0.06
51 INT331227 Binding of Becn1 and Pink1 1 0.03 1.13 0.05
52 INT317035 UBQLN1 Regulation of Localization of Gabrg1 1 0.12 0 0.03
53 INT265347 Binding of Ocln and Tgfbr1 1 0.18 0.06 0.03
54 INT265345 Binding of Tgfbr1 and Tjp1 1 0.09 0.06 0.03
55 INT265343 Positive_regulation of Binding of Tgfbr1 and Tjp1 1 0.12 0.06 0.03
56 INT265348 Positive_regulation of Binding of Ocln and Tgfbr1 1 0.25 0.06 0.03
57 INT342725 Pink1 Positive_regulation of Phosphorylation of Park2 1 0.29 0.62 0
58 INT342730 Pink1 Positive_regulation of Phosphorylation of Trap1 1 0.17 0.98 0
59 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
60 INT342737 Pink1 Positive_regulation of HTRA2 1 0.29 0.58 0
61 INT342728 Pink1 Positive_regulation of Trap1 1 0.17 0.98 0
62 INT337915 Tgfbr1 Positive_regulation of Negative_regulation of Smad2 1 0.05 0.15 0
63 INT265344 sb Negative_regulation of Tgfbr1 1 0.00 0.06 0
64 INT342731 Pink1 Regulation of Localization of Gfm1 1 0.00 0.61 0
65 INT317300 Binding of Park2 and Pink1 1 0.48 1.23 0
66 INT279145 Binding of VHL and RNF139 1 0.30 1.87 0
67 INT279143 Binding of TSN and RNF139 1 0.31 0.83 0
68 INT342727 Pink1 Positive_regulation of Park2 1 0.29 0.62 0
69 INT342736 Pink1 Positive_regulation of Phosphorylation of HTRA2 1 0.29 0.58 0
70 INT279144 RNF139 Regulation of TSN 1 0.24 3.47 0
71 INT317307 Binding of Hsp90aa1 and Pink1 1 0.12 0.56 0
72 INT204995 Ppp1r15b Regulation of Gene_expression of Pink1 1 0.01 0.97 0
73 INT317319 Binding of Trap1 and Pink1 1 0.26 2.67 0
74 INT310192 Tgfbr1 Positive_regulation of Regulation of Acvrl1 1 0.01 0 0
75 INT204994 Positive_regulation of Hras1 Positive_regulation of Gene_expression of Pink1 1 0.05 0.97 0
76 INT317306 Binding of Mul1 and Pink1 1 0.01 0.62 0
77 INT342729 Pink1 Regulation of Phosphorylation of Trap1 1 0.09 0.48 0
78 INT337917 Binding of sb and Tgfbr1 1 0.00 1.06 0
79 INT317311 Binding of Cdc37 and Pink1 1 0.13 0.56 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for regulation of protein ubiquitination. They are ordered first by their pain relevance and then by number of times they were reported in regulation of protein ubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT30197 Positive_regulation of Ubqln1 26 0.08 2.07 18.28
2 INT30193 Localization of Ubqln1 20 0.12 1.69 11.09
3 INT30195 Gene_expression of Ubqln1 12 0.10 1.09 5.89
4 INT71362 Negative_regulation of Ubqln1 5 0.04 1.31 5.63
5 INT139749 Regulation of Ubqln1 10 0.02 2.47 5.38
6 INT204971 Gene_expression of Pink1 42 0.77 23.95 4.75
7 INT108919 Positive_regulation of Mapk9 9 0.34 3.55 4.74
8 INT104480 Phosphorylation of Mapk9 8 0.80 6.59 3.62
9 INT75484 Gene_expression of Tgfbr1 21 0.64 13.36 3.15
10 INT26575 Binding of Ubqln1 4 0.48 1.11 3.06
11 INT30194 Positive_regulation of Localization of Ubqln1 5 0.08 0 2.99
12 INT214348 Regulation of Localization of Ubqln1 3 0.01 0.29 2.57
13 INT30196 Positive_regulation of Gene_expression of Ubqln1 4 0.08 0.29 2.06
14 INT108921 Negative_regulation of Positive_regulation of Mapk9 3 0.25 1.8 1.99
15 INT104478 Positive_regulation of Mapk9 5 0.67 5.56 1.81
16 INT104479 Negative_regulation of Mapk9 3 0.37 2.83 1.69
17 INT142678 Positive_regulation of Phosphorylation of Mapk9 4 0.51 2.1 1.6
18 INT142676 Phosphorylation of Mapk9 5 0.61 1.48 1.48
19 INT159784 Gene_expression of Mapk9 8 0.61 6.28 1.37
20 INT142679 Negative_regulation of Phosphorylation of Mapk9 1 0.17 0.51 1.37
21 INT90226 Gene_expression of Mapk9 3 0.65 1.94 1.34
22 INT224447 Gene_expression of FBXO2 7 0.75 7.33 1.31
23 INT310164 Negative_regulation of Gene_expression of Tgfbr1 9 0.40 6.11 1.17
24 INT140054 Negative_regulation of Mapk9 3 0.25 1.9 1.05
25 INT133608 Regulation of Daxx 1 0.16 0.28 0.93
26 INT265313 Positive_regulation of Tgfbr1 8 0.66 2.95 0.87
27 INT196583 Regulation of Phosphorylation of Mapk9 1 0.37 0.5 0.85
28 INT104482 Positive_regulation of Phosphorylation of Mapk9 2 0.49 1.55 0.84
29 INT161947 Positive_regulation of TGFBR1 2 0.52 1.6 0.76
30 INT204969 Negative_regulation of Pink1 1 0.58 7.03 0.75
31 INT144880 Negative_regulation of DAXX 4 0.23 2.15 0.73
32 INT104488 Negative_regulation of Phosphorylation of Mapk9 1 0.41 1.03 0.72
33 INT133603 Gene_expression of Daxx 1 0.28 0.27 0.7
34 INT133606 Regulation of Gene_expression of Daxx 1 0.16 0.27 0.7
35 INT296589 Localization of Pink1 1 0.08 0.65 0.61
36 INT144922 Gene_expression of TGFBR1 4 0.72 0.19 0.57
37 INT104483 Positive_regulation of Positive_regulation of Mapk9 1 0.49 0.75 0.56
38 INT104484 Regulation of Mapk9 1 0.12 0.73 0.55
39 INT214356 Negative_regulation of Localization of Ubqln1 1 0.01 0.17 0.51
40 INT167975 Negative_regulation of Gene_expression of Mapk9 2 0.02 1.18 0.47
41 INT155088 Positive_regulation of DAXX 1 0.22 1.27 0.45
42 INT292484 Negative_regulation of TGFBR1 3 0.19 0.75 0.39
43 INT162983 Binding of Daxx 1 0.10 0.1 0.36
44 INT349967 Regulation of Negative_regulation of Ubqln1 1 0.01 0 0.35
45 INT130043 Positive_regulation of Daxx 1 0.51 0.54 0.35
46 INT342161 Positive_regulation of Gene_expression of Mapk9 1 0.09 0.63 0.35
47 INT254816 Negative_regulation of Tgfbr1 20 0.55 9.24 0.34
48 INT311881 Regulation of Positive_regulation of Tgfbr1 1 0.22 0.97 0.29
49 INT214358 Positive_regulation of Regulation of Ubqln1 1 0.01 0.08 0.25
50 INT224449 Positive_regulation of Gene_expression of FBXO2 3 0.49 1.72 0.24
51 INT243930 Binding of Ubqln1 1 0.04 0.09 0.23
52 INT154934 Negative_regulation of Positive_regulation of Mapk9 1 0.35 0.41 0.23
53 INT140059 Localization of Mapk9 1 0.28 0.61 0.23
54 INT311886 Phosphorylation of Tgfbr1 1 0.40 0.7 0.19
55 INT224448 Positive_regulation of FBXO2 1 0.49 0.72 0.19
56 INT204987 Binding of Pink1 3 0.37 4.72 0.17
57 INT204983 Positive_regulation of Gene_expression of Pink1 1 0.50 2.03 0.16
58 INT204975 Positive_regulation of Pink1 7 0.69 5.17 0.14
59 INT302662 Negative_regulation of Negative_regulation of TGFBR1 1 0.14 0 0.13
60 INT140057 Negative_regulation of Negative_regulation of Mapk9 1 0.15 0.31 0.12
61 INT140051 Negative_regulation of Localization of Mapk9 1 0.20 0.31 0.11
62 INT254819 Regulation of Negative_regulation of Tgfbr1 1 0.15 1.2 0.09
63 INT178419 Regulation of Mapk9 1 0.09 0.76 0.08
64 INT311885 Positive_regulation of Gene_expression of Tgfbr1 2 0.44 0.35 0.06
65 INT279147 Negative_regulation of RNF139 1 0.53 5.41 0.06
66 INT265316 Binding of Tgfbr1 2 0.35 0.59 0
67 INT265326 Regulation of Tgfbr1 2 0.43 0.17 0
68 INT204981 Positive_regulation of Protein_catabolism of Pink1 1 0.46 1.43 0
69 INT279150 Gene_expression of RNF139 1 0.71 11.45 0
70 INT315214 Negative_regulation of Regulation of Tgfbr1 1 0.41 0 0
71 INT279152 Positive_regulation of RNF139 1 0.46 1.29 0
72 INT268388 Positive_regulation of Positive_regulation of TGFBR1 1 0.35 0.61 0
73 INT244184 Binding of FBXO2 1 0.03 0 0
74 INT342712 Phosphorylation of Pink1 1 0.32 0.62 0
75 INT204979 Protein_catabolism of Pink1 1 0.99 1.43 0
76 INT279153 Negative_regulation of Gene_expression of RNF139 1 0.53 0.57 0
77 INT272228 Localization of TGFBR1 1 0.34 0.74 0
78 INT265319 Positive_regulation of Negative_regulation of Tgfbr1 1 0.47 0.53 0
79 INT342724 Transcription of Pink1 1 0.35 0.31 0
80 INT144920 Positive_regulation of Gene_expression of TGFBR1 1 0.65 0 0
81 INT317282 Regulation of Pink1 1 0.40 1.26 0
82 INT244181 Localization of FBXO2 1 0.05 0 0
83 INT290403 Regulation of Gene_expression of Mapk9 1 0.28 0.15 0
84 INT204988 Regulation of Gene_expression of Pink1 1 0.45 1.91 0
85 INT279161 Transcription of RNF139 1 0.63 1.36 0
86 INT310176 Localization of Tgfbr1 1 0.11 0.83 0
87 INT310179 Positive_regulation of Positive_regulation of Tgfbr1 1 0.08 0 0
88 INT279159 Regulation of RNF139 1 0.56 2.98 0
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