GO:0031398

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Name positive regulation of protein ubiquitination
Categary Process
Go Slim No
Go Link GO:0031398
Unique Molecular Interactions 175
Total Molecular Interactions 233
Total Single Events 1301
Pain Genes Associated 39

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein ubiquitination. They are ordered first by their pain relevance and then by number of times they were reported for positive regulation of protein ubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT63918 Binding of Cck and Ripk2 1 0.28 0 2.07
2 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
3 INT85686 Binding of Arrb1 and Arrb2 1 0.14 0.09 0.79
4 INT282665 Binding of Gfap and Ticam1 1 0.01 0 0.69
5 INT254348 Binding of ANGPT1 and TEK 1 0.04 1.72 0.48
6 INT291616 Cby1 Positive_regulation of Gene_expression of Smad7 1 0.00 0.79 0.38
7 INT4382 RIPK2 Regulation of INS 1 0.12 0.58 0.36
8 INT353454 Binding of BRCA1 and IL17A 1 0.00 2.55 0.36
9 INT224700 TNF Positive_regulation of Angpt1 1 0.00 0.63 0.34
10 INT353452 Binding of AGRP and BRCA1 1 0.00 3.89 0.34
11 INT4381 RIPK2 Positive_regulation of Localization of INS 1 0.13 0.53 0.34
12 INT324690 Binding of Traf6 and Ticam1 2 0.07 0.23 0.33
13 INT181899 TNF Regulation of ANGPT1 1 0.03 1.22 0.33
14 INT198566 Ddit4l Regulation of Axin1 1 0.03 1 0.31
15 INT285564 Binding of IL1B and Ripk2 1 0.04 0.76 0.31
16 INT318323 Binding of GRB2 and HSPA5 1 0.34 0.28 0.31
17 INT306323 Tlr4 Positive_regulation of Ticam1 3 0.25 0.55 0.3
18 INT353448 BRCA1 Positive_regulation of CCL2 1 0.01 1.37 0.26
19 INT353449 BRCA1 Positive_regulation of IL4 1 0.00 1.37 0.26
20 INT353455 BRCA1 Positive_regulation of IL13 1 0.00 1.37 0.26
21 INT158621 Binding of SIGMAR1 and Sphk1 1 0.01 0 0.25
22 INT243640 Binding of Twist1 and Stub1 1 0.08 0.34 0.24
23 INT333927 GLUL Positive_regulation of HSPA5 1 0.17 0.78 0.24
24 INT192864 Binding of Hspa5 and Mela 1 0.25 1.06 0.22
25 INT303029 Binding of TEK and Angpt1 1 0.26 1.82 0.22
26 INT256706 Binding of Hsp90b1 and Wfs1 1 0.43 5.02 0.2
27 INT55252 Binding of CCK and RIPK2 1 0.40 0 0.2
28 INT343837 TICAM1 Positive_regulation of IRF3 1 0.03 0.19 0.19
29 INT343831 TICAM1 Positive_regulation of Gene_expression of TLR4 1 0.11 0.19 0.19
30 INT343852 Binding of TRAF1 and TICAM1 1 0.03 0.19 0.17
31 INT217074 Binding of Acsm3 and Axin1 1 0.00 5.37 0.17
32 INT130690 Gene_expression of HSPA5 Negative_regulation of Positive_regulation of DDIT3 1 0.21 0.58 0.17
33 INT343850 Binding of TRAF4 and TICAM1 1 0.03 0.19 0.17
34 INT343915 Binding of Traf1 and TICAM1 1 0.08 0.19 0.17
35 INT204791 Binding of Spg7 and Nod2 1 0.03 0.5 0.16
36 INT204789 Binding of Tlr2 and Nod2 1 0.23 0.44 0.16
37 INT329796 TICAM1 Positive_regulation of IFNA1 2 0.02 0.89 0.15
38 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14
39 INT353451 Binding of BRCA1 and CRP 1 0.01 1.18 0.14
40 INT353453 Binding of BRCA1 and IL4 1 0.00 1.18 0.14
41 INT209645 AR Regulation of STUB1 1 0.04 0.93 0.13
42 INT145830 Mdp1 Positive_regulation of Nod2 1 0.34 0.52 0.13
43 INT324831 Binding of TRIM63 and Ticam1 1 0.01 0.09 0.12
44 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12
45 INT254229 Binding of Ticam1 and Positive_regulation of Binding of IFNA1 1 0.02 0.3 0.12
46 INT254207 Ticam1 Positive_regulation of Ik 1 0.00 0.14 0.12
47 INT254227 Binding of Ripk1 and Ticam1 3 0.07 0.18 0.11
48 INT254215 Binding of Tlr4 and Ticam1 2 0.09 0.76 0.11
49 INT334264 Binding of Gtf3a and Ticam1 1 0.00 0.18 0.11
50 INT254220 Binding of Ticam1 and Sarm1 1 0.09 0.22 0.11
51 INT324869 Binding of Jun and Ticam1 1 0.01 0.76 0.11
52 INT324870 Binding of Ticam1 and Tlr3 1 0.03 0.76 0.11
53 INT329798 Binding of MYD88 and TICAM1 2 0.01 0.24 0.1
54 INT192249 Angpt1 Positive_regulation of Localization of NOS3 1 0.01 0.46 0.09
55 INT343845 TICAM1 Positive_regulation of TIRAP 1 0.05 0.25 0.09
56 INT228808 Smad7 Regulation of Rgs1 1 0.19 0.24 0.09
57 INT192248 Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
58 INT192250 Positive_regulation of Angpt1 Positive_regulation of NOS3 1 0.01 0.46 0.09
59 INT228812 Smad7 Regulation of Stap1 1 0.00 0.24 0.09
60 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
61 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
62 INT192862 Binding of Esr1 and Hspa5 1 0.08 0.68 0.08
63 INT215880 Car2 Regulation of Hspa5 1 0.09 0.66 0.08
64 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
65 INT312645 Binding of DNAJA3 and Musk 1 0.08 0.96 0.07
66 INT346499 Mal Positive_regulation of TICAM1 1 0.06 0.66 0.07
67 INT290905 Gene_expression of Shh Positive_regulation of Gene_expression of Angpt1 1 0.14 0 0.06
68 INT346449 TICAM1 Positive_regulation of TBK1 1 0.01 0.45 0.06
69 INT298258 Binding of Runx3 and Stub1 1 0.11 0.18 0.06
70 INT346454 TICAM1 Positive_regulation of IKBKE 1 0.01 0.45 0.06
71 INT350478 Tirap Regulation of Ticam1 1 0.07 0.06 0.05
72 INT353450 Binding of BRCA1 and VEGFA 1 0.01 0.82 0.05
73 INT250865 Binding of Fgf8 and Fgfr3 1 0.18 0.3 0.05
74 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05
75 INT207760 Fkbp1a Regulation of MSMB 1 0.12 0.69 0.04
76 INT215876 Atf4 Regulation of Hspa5 1 0.22 0.43 0.04
77 INT201766 Binding of RIPK2 and Ngfr 1 0.02 0.41 0.04
78 INT350800 Binding of TLR3 and TICAM1 1 0.01 0 0.04
79 INT213815 Binding of Tfeb and Stub1 1 0.13 0.09 0.04
80 INT178501 Angpt1 Positive_regulation of Tek 1 0.06 0.78 0.04
81 INT298703 Angpt1 Regulation of Tek 1 0.12 0.27 0.03
82 INT353287 Prdx2 Positive_regulation of Phosphorylation of Smad7 1 0.22 0.06 0.03
83 INT353291 Prdx2 Positive_regulation of Smad7 1 0.31 0.06 0.03
84 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03
85 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03
86 INT348028 Binding of Traf3 and Ticam1 1 0.01 0.56 0.03
87 INT353288 Smad7 Negative_regulation of Phosphorylation of Tgif1 1 0.08 0.06 0.03
88 INT221262 Binding of BRCA1 and CD4 1 0.22 0.81 0.03
89 INT342733 Gene_expression of Lrrk2 Positive_regulation of Apaf1 1 0.10 0.74 0.03
90 INT234178 Binding of BRCA1 and BRCA2 2 0.40 1.52 0
91 INT120077 Gene_expression of Smad7 Negative_regulation of Positive_regulation of Itk 1 0.02 0.27 0
92 INT291199 Binding of VEGFA and Angpt1 1 0.08 0.69 0
93 INT287676 Negative_regulation of Sphk1 Negative_regulation of Pik3r1 1 0.14 0.42 0
94 INT256703 Negative_regulation of Hsp90b1 Positive_regulation of Wfs1 1 0.42 0.24 0
95 INT265231 Binding of FKBP1A and TGFBR1 1 0.11 0.35 0
96 INT181169 TAPBP Negative_regulation of MALT1 1 0.00 0.48 0
97 INT201534 RASSF1 Negative_regulation of ID2 1 0.33 1.41 0
98 INT313117 Binding of Stub1 and Carf 1 0.10 0 0
99 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0
100 INT256700 Negative_regulation of Binding of Hsp90b1 and Wfs1 1 0.52 0 0
101 INT273116 Binding of Fkbp1a and Mtor 1 0.37 0 0
102 INT343842 Binding of TRAM1 and TICAM1 1 0.01 0.12 0
103 INT312642 DNAJA3 Positive_regulation of Musk 1 0.08 0.37 0
104 INT292088 Binding of AMELX and ANGPT1 1 0.00 0.9 0
105 INT234180 Binding of BRCA1 and BRIP1 1 0.33 1.37 0
106 INT218663 Olr811 Positive_regulation of Gene_expression of Smad7 1 0.01 0.45 0
107 INT201532 RASSF1 Regulation of NPC1 1 0.44 1.41 0
108 INT314743 Binding of RAD51 and Brca1 1 0.06 1.06 0
109 INT314740 Binding of ESR1 and Brca1 1 0.16 0.69 0
110 INT134836 Binding of SMAD7 and YAP1 1 0.53 0.89 0
111 INT206943 Hspa5 Positive_regulation of Atf4 1 0.47 0.62 0
112 INT287885 Binding of DVL1 and AXIN1 1 0.02 0 0
113 INT294066 ANGPT1 Positive_regulation of VEGFA 1 0.01 0.1 0
114 INT287673 Negative_regulation of Sphk1 Negative_regulation of Akt1 1 0.20 0.42 0
115 INT272017 TBC1D7 Positive_regulation of Protein_catabolism of Tsc1 1 0.08 0.46 0
116 INT232595 Binding of BRCA1 and HEPACAM 1 0.02 0.89 0
117 INT109817 Ace2 Positive_regulation of Angpt1 1 0.05 0.31 0
118 INT310188 Binding of Adcyap1r1 and Smad7 1 0.00 0 0
119 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0
120 INT347155 Mirlet7a-1 Negative_regulation of Smad7 1 0.10 0 0
121 INT265233 Binding of APC and FKBP1A 1 0.08 0.41 0
122 INT236724 Binding of AXIN1 and Ctnnd2 1 0.39 1.03 0
123 INT225597 Binding of Gfer and Paxip1 1 0.02 0 0
124 INT201542 Positive_regulation of RASSF1 Negative_regulation of ID2 1 0.36 1.41 0
125 INT268887 Binding of ANGPT1 and Tek 1 0.10 0 0
126 INT243635 Positive_regulation of Binding of Nfatc2 and Stub1 1 0.09 0 0
127 INT256705 Binding of Wfs1 and Xbp1 1 0.19 0.39 0
128 INT225551 Binding of Paxip1 and Ncoa6 1 0.26 0.47 0
129 INT176096 Regulation of Binding of Angpt1 and Tek 1 0.07 0.54 0
130 INT263584 Hspa5 Positive_regulation of Myo1b 1 0.00 1.02 0
131 INT335526 SPHK1 Regulation of Gene_expression of SGCB 1 0.27 0.86 0
132 INT318922 XIAP Regulation of COMMD1 1 0.09 0.37 0
133 INT265234 Binding of FKBP1A and SGCG 1 0.03 0.35 0
134 INT335525 Binding of SGCB and SPHK1 1 0.22 1.61 0
135 INT176097 Binding of Angpt1 and Tek 1 0.06 0.48 0
136 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0
137 INT265232 Regulation of Binding of APC and FKBP1A 1 0.08 0.41 0
138 INT346743 Atf6 Positive_regulation of Hspa5 1 0.00 0 0
139 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0
140 INT314745 Binding of TP53 and Brca1 1 0.18 1.17 0
141 INT271999 Binding of Fkbp1a and Positive_regulation of Negative_regulation of Mtor 1 0.00 0.18 0
142 INT201536 RASSF1 Regulation of ID2 1 0.41 1.42 0
143 INT343824 Binding of TICAM1 and TICAM2 1 0.03 0.12 0
144 INT256704 Xbp1 Positive_regulation of Positive_regulation of Wfs1 1 0.26 0.4 0
145 INT190681 Binding of Bcl2 and Fkbp1a 1 0.01 0.46 0
146 INT243628 Binding of Nfatc2 and Stub1 1 0.06 0 0
147 INT225599 Ncoa6 Negative_regulation of Paxip1 1 0.26 0.2 0
148 INT256702 Binding of Wfs1 and Tmed4 1 0.01 0.61 0
149 INT271994 Binding of Fkbp1a and Mtor 1 0.00 0.22 0
150 INT270460 Shh Positive_regulation of Gene_expression of Angpt1 1 0.04 0.08 0
151 INT225537 Binding of Paxip1 and Mll2 1 0.12 0 0
152 INT296162 Mcph1 Regulation of Brca1 1 0.26 0.19 0
153 INT201533 RASSF1 Positive_regulation of Gene_expression of ID2 1 0.38 1.41 0
154 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0
155 INT263586 Hspa5 Positive_regulation of Esr1 1 0.15 1.01 0
156 INT242612 Bcl10 Positive_regulation of Skull19 1 0.01 1.2 0
157 INT351095 Binding of FKBP1A and RPS6KB1 1 0.24 0.36 0
158 INT351101 Negative_regulation of Binding of FKBP1A and RPS6KB1 1 0.27 0.36 0
159 INT254231 Binding of TRAM1 and Ticam1 1 0.03 0 0
160 INT318919 Binding of ATP7B and COMMD1 1 0.37 0.76 0
161 INT351096 Binding of FKBP1A and MTOR 1 0.28 1.35 0
162 INT307156 Esr1 Positive_regulation of Hspa5 1 0.04 0.79 0
163 INT318920 Binding of XIAP and COMMD1 1 0.12 0.78 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for positive regulation of protein ubiquitination. They are ordered first by their pain relevance and then by number of times they were reported in positive regulation of protein ubiquitination. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT38503 Positive_regulation of Ripk2 11 0.67 2.9 7.47
2 INT117621 Positive_regulation of HSPA5 17 0.59 13.26 6.06
3 INT37976 Binding of Ripk2 6 0.47 0.27 5.01
4 INT20459 Regulation of Ripk2 5 0.44 0 4.53
5 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46
6 INT119063 Gene_expression of BRCA1 24 0.67 30.04 4.17
7 INT120072 Gene_expression of Smad7 38 0.74 20.87 3.69
8 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31
9 INT6025 Negative_regulation of RIPK2 4 0.57 0.96 2.82
10 INT130700 Gene_expression of HSPA5 16 0.75 11.55 2.81
11 INT19421 Positive_regulation of RIPK2 6 0.49 5.63 2.72
12 INT221269 Binding of BRCA1 14 0.40 31.77 2.7
13 INT130702 Positive_regulation of Gene_expression of HSPA5 7 0.59 7.53 2.68
14 INT61004 Negative_regulation of Regulation of Ripk2 1 0.41 0 2.68
15 INT138437 Gene_expression of Sphk1 23 0.65 10.01 2.61
16 INT153718 Gene_expression of ANGPT1 15 0.45 10.82 2.13
17 INT37977 Negative_regulation of Ripk2 3 0.42 0.92 2.03
18 INT134919 Binding of Ticam1 6 0.18 1.12 1.94
19 INT138439 Positive_regulation of Gene_expression of Sphk1 14 0.48 5.93 1.86
20 INT154816 Negative_regulation of Sphk1 19 0.41 11.38 1.84
21 INT174924 Gene_expression of Smad7 6 0.41 3.59 1.76
22 INT37978 Localization of Ripk2 4 0.78 0.57 1.73
23 INT174923 Positive_regulation of Gene_expression of Smad7 3 0.37 2.3 1.73
24 INT55511 Positive_regulation of Binding of Ripk2 1 0.49 0.19 1.69
25 INT221422 Positive_regulation of BRCA1 5 0.23 12.63 1.53
26 INT123926 Gene_expression of Angpt1 28 0.54 21.74 1.47
27 INT118559 Positive_regulation of Hspa5 20 0.61 15.66 1.45
28 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36
29 INT204766 Gene_expression of Nod2 4 0.75 4.14 1.3
30 INT178494 Gene_expression of Angpt1 10 0.37 9.77 1.28
31 INT39144 Gene_expression of RIPK2 5 0.75 2.56 1.27
32 INT120076 Positive_regulation of Gene_expression of Smad7 16 0.65 11.33 1.25
33 INT109078 Positive_regulation of ANGPT1 7 0.22 3.08 1.21
34 INT138434 Positive_regulation of Sphk1 10 0.48 2.18 1.18
35 INT38502 Gene_expression of Ripk2 3 0.65 0.17 1.16
36 INT46734 Positive_regulation of Stub1 6 0.16 1.44 1.09
37 INT134917 Localization of Ticam1 2 0.51 0.6 0.99
38 INT19422 Protein_catabolism of RIPK2 2 0.86 0.62 0.97
39 INT36850 Negative_regulation of Negative_regulation of RIPK2 1 0.57 0 0.97
40 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94
41 INT38426 Regulation of RIPK2 3 0.60 0.62 0.91
42 INT42076 Regulation of Negative_regulation of RIPK2 1 0.44 0.91 0.91
43 INT159015 Positive_regulation of Localization of HSPA5 1 0.36 0.33 0.88
44 INT159013 Localization of HSPA5 2 0.42 0.32 0.87
45 INT134912 Positive_regulation of Localization of Ticam1 1 0.24 0.32 0.87
46 INT24372 Negative_regulation of Sphk1 1 0.59 0 0.85
47 INT55512 Positive_regulation of Localization of Ripk2 1 0.67 0.09 0.85
48 INT99156 Binding of HSPA5 3 0.38 0.57 0.84
49 INT109080 Negative_regulation of ANGPT1 8 0.14 3.17 0.82
50 INT40227 Regulation of Positive_regulation of Ripk2 1 0.44 0 0.82
51 INT85678 Binding of Arrb1 1 0.20 0.09 0.78
52 INT118469 Gene_expression of Fgfr3 5 0.72 6.98 0.75
53 INT37975 Negative_regulation of Binding of Ripk2 1 0.57 0 0.75
54 INT272878 Negative_regulation of Smad7 4 0.41 3.86 0.72
55 INT123927 Positive_regulation of Gene_expression of Angpt1 12 0.48 10.18 0.71
56 INT24373 Gene_expression of Sphk1 3 0.67 0 0.68
57 INT196939 Gene_expression of Stub1 10 0.18 1.67 0.59
58 INT221420 Positive_regulation of Gene_expression of BRCA1 2 0.24 2.17 0.55
59 INT232453 Negative_regulation of DNAJA3 1 0.41 0 0.54
60 INT24375 Regulation of Sphk1 1 0.62 0 0.5
61 INT19420 Positive_regulation of Positive_regulation of RIPK2 1 0.49 0.59 0.5
62 INT120074 Regulation of Gene_expression of Smad7 1 0.58 2.05 0.5
63 INT89258 Localization of STUB1 3 0.14 0.67 0.49
64 INT204781 Positive_regulation of Nod2 6 0.45 2.79 0.46
65 INT24371 Positive_regulation of Sphk1 2 0.41 2.37 0.46
66 INT209013 Regulation of Stub1 1 0.06 0.29 0.46
67 INT210125 Regulation of Axin1 1 0.02 2.45 0.46
68 INT38738 Localization of RIPK2 2 0.68 0.07 0.45
69 INT154748 Positive_regulation of Gene_expression of Hspa5 11 0.44 7.66 0.44
70 INT96909 Regulation of Angpt1 2 0.17 0.37 0.43
71 INT224538 Negative_regulation of Gene_expression of Smad7 1 0.09 0.25 0.43
72 INT44600 Gene_expression of MALT1 6 0.75 6.14 0.42
73 INT130698 Negative_regulation of Positive_regulation of HSPA5 2 0.36 1.58 0.42
74 INT178497 Positive_regulation of Gene_expression of Angpt1 4 0.19 3.65 0.39
75 INT156120 Localization of Arrb1 1 0.00 0 0.38
76 INT94933 Positive_regulation of Gene_expression of Bcl10 1 0.01 1.74 0.38
77 INT156119 Positive_regulation of Localization of Arrb1 1 0.00 0 0.38
78 INT250167 Negative_regulation of Ticam1 3 0.29 2.03 0.37
79 INT256681 Regulation of Wfs1 8 0.43 4.72 0.36
80 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36
81 INT30049 Gene_expression of Bcl10 4 0.51 2.36 0.35
82 INT207064 Gene_expression of Fkbp1a 2 0.32 1.52 0.34
83 INT353457 Positive_regulation of Binding of BRCA1 1 0.09 1.69 0.34
84 INT207065 Localization of Fkbp1a 1 0.36 0.82 0.33
85 INT144854 Gene_expression of STUB1 10 0.13 2.03 0.31
86 INT221419 Regulation of BRCA1 5 0.35 6.18 0.31
87 INT174808 Regulation of COMMD1 2 0.01 1.35 0.31
88 INT134840 Gene_expression of SMAD7 1 0.74 2.74 0.31
89 INT24374 Regulation of Gene_expression of Sphk1 1 0.45 0 0.31
90 INT184716 Binding of Smad7 2 0.34 0.91 0.29
91 INT272890 Regulation of Negative_regulation of Smad7 1 0.19 1.33 0.29
92 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28
93 INT202802 Regulation of Fkbp1a 4 0.26 0.96 0.28
94 INT346895 Positive_regulation of Gene_expression of Nod2 1 0.33 0.74 0.28
95 INT333957 Regulation of HSPA5 3 0.52 0.61 0.27
96 INT144855 Positive_regulation of STUB1 3 0.08 0.59 0.26
97 INT346896 Binding of Nod2 1 0.21 0.72 0.26
98 INT256682 Gene_expression of Wfs1 1 0.74 6.63 0.25
99 INT254195 Gene_expression of Ticam1 3 0.29 0.46 0.24
100 INT302791 Negative_regulation of Gene_expression of Sphk1 1 0.23 0.34 0.24
101 INT96908 Protein_catabolism of Angpt1 1 0.41 0.26 0.24
102 INT228793 Negative_regulation of Gene_expression of Smad7 5 0.25 2.33 0.23
103 INT220396 Negative_regulation of Angpt1 4 0.26 1.64 0.23
104 INT174809 Gene_expression of COMMD1 1 0.01 0.77 0.23
105 INT142482 Positive_regulation of Positive_regulation of HSPA5 1 0.28 1.17 0.22
106 INT346899 Regulation of Positive_regulation of Nod2 1 0.18 0.75 0.22
107 INT203471 Localization of Stub1 1 0.23 0.5 0.21
108 INT172021 Localization of Hspa5 2 0.18 0.93 0.2
109 INT181791 Positive_regulation of Gene_expression of ANGPT1 1 0.29 1.27 0.2
110 INT280593 Negative_regulation of Gene_expression of SPHK1 2 0.43 3.92 0.19
111 INT164519 Gene_expression of FKBP1A 2 0.39 0.22 0.19
112 INT280594 Gene_expression of SPHK1 2 0.78 71.47 0.19
113 INT144676 Gene_expression of Hspa5 1 0.06 1.12 0.19
114 INT221268 Localization of BRCA1 7 0.63 4.83 0.18
115 INT119061 Negative_regulation of Gene_expression of BRCA1 4 0.51 0.85 0.18
116 INT324768 Positive_regulation of Ticam1 2 0.16 0.14 0.18
117 INT89689 Binding of Brca1 2 0.37 2.55 0.18
118 INT276401 Localization of MALT1 1 0.60 3.62 0.18
119 INT201691 Binding of RIPK2 2 0.18 1.51 0.17
120 INT256696 Positive_regulation of Wfs1 1 0.66 9.14 0.17
121 INT210123 Localization of Axin1 1 0.04 0.84 0.17
122 INT66933 Binding of AXIN1 6 0.32 1.8 0.16
123 INT192842 Binding of Hspa5 3 0.33 1.48 0.16
124 INT154746 Regulation of Positive_regulation of Hspa5 1 0.40 0.18 0.16
125 INT256684 Positive_regulation of Gene_expression of Wfs1 1 0.66 3.62 0.16
126 INT156590 Negative_regulation of Negative_regulation of ANGPT1 1 0.10 0.33 0.16
127 INT228790 Positive_regulation of Smad7 4 0.41 0.58 0.15
128 INT240596 Negative_regulation of Gene_expression of RIPK2 1 0.06 0.91 0.15
129 INT324781 Protein_catabolism of Ticam1 1 0.27 0.74 0.15
130 INT254190 Positive_regulation of Binding of Ticam1 1 0.22 0.32 0.15
131 INT136002 Positive_regulation of Gene_expression of RIPK2 1 0.67 0.52 0.15
132 INT290923 Positive_regulation of Angpt1 3 0.48 3.62 0.14
133 INT287672 Positive_regulation of Positive_regulation of Sphk1 1 0.48 0.38 0.14
134 INT263410 Negative_regulation of Axin1 1 0.01 0 0.14
135 INT59955 Gene_expression of RASSF1 3 0.60 3.43 0.13
136 INT280581 Regulation of SPHK1 2 0.45 1.33 0.13
137 INT280589 Localization of SPHK1 2 0.75 2.61 0.13
138 INT158618 Binding of Sphk1 1 0.01 0 0.13
139 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13
140 INT187590 Gene_expression of Brca1 12 0.65 4.94 0.11
141 INT208914 Regulation of Brca1 1 0.10 0.79 0.11
142 INT354414 Localization of ANGPT1 1 0.10 0 0.1
143 INT287665 Regulation of Negative_regulation of Sphk1 1 0.43 0.11 0.1
144 INT144677 Positive_regulation of Gene_expression of Hspa5 1 0.04 0.59 0.1
145 INT229187 Binding of MALT1 2 0.31 1.48 0.09
146 INT144094 Negative_regulation of Localization of Ripk2 1 0.42 0.49 0.09
147 INT204777 Negative_regulation of Localization of Nod2 1 0.28 0.61 0.09
148 INT144668 Positive_regulation of Hspa5 1 0.03 0.53 0.09
149 INT256675 Regulation of Gene_expression of Wfs1 1 0.43 2.33 0.09
150 INT299319 Localization of FKBP1A 1 0.44 0 0.09
151 INT256687 Positive_regulation of Transcription of Wfs1 1 0.44 1.95 0.09
152 INT184167 Binding of STUB1 5 0.07 0.72 0.08
153 INT192840 Transcription of Hspa5 4 0.47 1.93 0.08
154 INT243617 Binding of Stub1 3 0.09 0.16 0.08
155 INT294014 Regulation of AXIN1 3 0.24 1.04 0.08
156 INT145364 Negative_regulation of AXIN1 2 0.33 0.52 0.08
157 INT291188 Regulation of Gene_expression of Angpt1 1 0.31 1.78 0.08
158 INT256693 Transcription of Wfs1 1 0.68 2.44 0.08
159 INT204779 Localization of Nod2 1 0.48 0.6 0.08
160 INT353267 Negative_regulation of Positive_regulation of Smad7 1 0.25 0.32 0.08
161 INT291183 Negative_regulation of Angpt1 1 0.30 0.89 0.08
162 INT181172 Positive_regulation of MALT1 1 0.01 0.27 0.08
163 INT250839 Binding of Fgfr3 1 0.16 0.19 0.08
164 INT174155 Negative_regulation of Brca1 4 0.36 1.77 0.07
165 INT59954 Localization of RASSF1 3 0.73 3.12 0.07
166 INT263572 Regulation of Hspa5 3 0.41 4.15 0.07
167 INT59953 Positive_regulation of Localization of RASSF1 1 0.00 0.75 0.07
168 INT333944 Regulation of Regulation of HSPA5 1 0.38 0.14 0.07
169 INT312616 Binding of DNAJA3 1 0.07 0.58 0.07
170 INT204770 Regulation of Nod2 1 0.29 0.66 0.07
171 INT219608 Regulation of RASSF1 1 0.01 0 0.07
172 INT291195 Negative_regulation of Gene_expression of Angpt1 1 0.41 2.29 0.07
173 INT254184 Positive_regulation of Gene_expression of Ticam1 1 0.22 0.11 0.06
174 INT290930 Localization of Angpt1 1 0.21 0 0.06
175 INT347149 Localization of Smad7 1 0.67 0 0.05
176 INT299313 Positive_regulation of Gene_expression of FKBP1A 1 0.29 0 0.05
177 INT337002 Positive_regulation of Binding of HSPA5 1 0.14 0.05 0.05
178 INT244699 Positive_regulation of AXIN1 1 0.02 0 0.05
179 INT130701 Negative_regulation of Gene_expression of HSPA5 1 0.50 0.5 0.05
180 INT290916 Regulation of Angpt1 2 0.31 1.01 0.04
181 INT258065 Protein_catabolism of ANGPT1 1 0.01 0.47 0.04
182 INT276397 Positive_regulation of Localization of MALT1 1 0.37 1.17 0.04
183 INT291193 Binding of Angpt1 1 0.26 1.87 0.04
184 INT342721 Localization of Lrrk2 1 0.39 0.67 0.04
185 INT276400 Positive_regulation of Binding of MALT1 1 0.37 1.09 0.04
186 INT346893 Negative_regulation of Gene_expression of Nod2 1 0.28 0.13 0.04
187 INT276403 Regulation of MALT1 3 0.34 3.37 0.03
188 INT342722 Gene_expression of Lrrk2 2 0.41 1.81 0.03
189 INT187589 Positive_regulation of Gene_expression of Brca1 2 0.55 1.93 0.03
190 INT344009 Negative_regulation of Localization of BRCA1 1 0.30 0.18 0.03
191 INT342711 Positive_regulation of Gene_expression of Lrrk2 1 0.36 0.73 0.03
192 INT182999 Negative_regulation of Gene_expression of STUB1 1 0.08 0.31 0.03
193 INT350784 Positive_regulation of TICAM1 1 0.05 0 0.03
194 INT350515 Transcription of SMAD7 1 0.07 0.38 0.03
195 INT353280 Phosphorylation of Smad7 1 0.48 0.06 0.03
196 INT294078 Regulation of ANGPT1 3 0.04 1.25 0
197 INT259116 Transcription of BRCA1 3 0.44 3.77 0
198 INT268882 Binding of ANGPT1 3 0.07 0.89 0
199 INT289783 Negative_regulation of Hspa5 2 0.22 0.7 0
200 INT263569 Phosphorylation of Hspa5 2 0.42 1.63 0
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