GO:0031419

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Name cobalamin binding
Categary Function
Go Slim No
Go Link GO:0031419
Unique Molecular Interactions 60
Total Molecular Interactions 79
Total Single Events 539
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for cobalamin binding. They are ordered first by their pain relevance and then by number of times they were reported for cobalamin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT91271 Mtr Regulation of Gene_expression of Il6 1 0.20 0 3.17
2 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 0.06 0 1.3
3 INT107561 Mtr Positive_regulation of Localization of Il1b 1 0.04 0.09 1.09
4 INT107563 Penk Regulation of Mtr 1 0.00 0.1 1.04
5 INT107565 Hps4 Regulation of Mtr 1 0.00 0.1 1.04
6 INT91273 Mtr Positive_regulation of Localization of Il6 1 0.17 0 0.88
7 INT54669 Mtr Regulation of Gene_expression of Il1 1 0.02 0.2 0.77
8 INT54668 Mtr Regulation of Gene_expression of Il1f5 1 0.00 0.2 0.76
9 INT44503 Cubn Positive_regulation of Prl 1 0.18 0 0.74
10 INT117012 Binding of OPRD1 and TCN2 1 0.02 0 0.72
11 INT46657 Mtr Regulation of Gnrh1 1 0.01 0 0.71
12 INT46656 Mtr Regulation of Prl 1 0.05 0 0.7
13 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69
14 INT38820 Binding of MTR and PDYN 1 0.03 0.19 0.65
15 INT27426 Mtr Positive_regulation of Localization of Il1f5 1 0.06 0 0.63
16 INT50935 Mtr Regulation of Gene_expression of Il6 1 0.00 0 0.53
17 INT28863 Mtr Negative_regulation of Dhfr 1 0.04 0.87 0.45
18 INT117011 Binding of TCN2 and TP53INP2 1 0.00 0 0.42
19 INT38269 Binding of TCN1 and CUBN 1 0.00 0.28 0.4
20 INT38274 Binding of TCN1 and Cbl 1 0.11 0.24 0.38
21 INT45196 Cubn Negative_regulation of Prl 1 0.05 0 0.27
22 INT50934 Mtr Positive_regulation of Gene_expression of Il6 1 0.00 0 0.2
23 INT202253 Binding of COMT and TCN1 1 0.16 0 0.12
24 INT202255 Binding of DRD2 and TCN1 1 0.16 0 0.12
25 INT239237 TCN2 Positive_regulation of Gene_expression of Serpine1 1 0.00 0.68 0.08
26 INT245985 Binding of MTR and Mtrr 1 0.06 0.8 0.07
27 INT245986 MTR Regulation of Mthfr 1 0.07 0.18 0.05
28 INT245981 Negative_regulation of TCN1 Regulation of Mthfr 1 0.03 0.18 0.05
29 INT310547 Binding of TCN1 and ERLIN1 1 0.00 0.17 0.05
30 INT245984 TCN1 Regulation of Mtrr 1 0.02 0.18 0.05
31 INT245966 TCN1 Regulation of MTR 1 0.02 0.18 0.05
32 INT245982 TCN1 Regulation of Mthfr 1 0.04 0.18 0.05
33 INT245983 Negative_regulation of TCN1 Regulation of Mtrr 1 0.02 0.18 0.05
34 INT245967 Negative_regulation of TCN1 Regulation of MTR 1 0.02 0.18 0.05
35 INT245987 Binding of MTR and Mthfr 1 0.11 0.48 0.03
36 INT232053 Binding of RNPC3 and LMBRD1 1 0.00 0.96 0
37 INT218531 Binding of C6 and TCN2 1 0.00 0 0
38 INT232044 Binding of FOXM1 and LMBRD1 1 0.00 0.32 0
39 INT218512 Binding of TCN2 and Cfb 1 0.00 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for cobalamin binding. They are ordered first by their pain relevance and then by number of times they were reported in cobalamin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT1672 Gene_expression of Mtr 18 0.67 3.39 13.32
2 INT8249 Positive_regulation of Cubn 15 0.66 4.05 9.35
3 INT13893 Negative_regulation of Cubn 9 0.36 1.78 9.24
4 INT9802 Positive_regulation of Mtr 9 0.60 3.69 7.43
5 INT46518 Localization of Mtr 12 0.65 1.31 6.55
6 INT10006 Regulation of Mtr 9 0.23 3.56 5.42
7 INT12250 Negative_regulation of Mtr 19 0.50 6.9 5.35
8 INT9803 Positive_regulation of Gene_expression of Mtr 3 0.60 1.45 4.36
9 INT18822 Regulation of Cubn 4 0.27 0.17 3.74
10 INT24751 Gene_expression of Mtr 8 0.36 1.34 3.34
11 INT195191 Gene_expression of Cubn 2 0.06 0 2.17
12 INT39453 Negative_regulation of TCN2 12 0.59 3.98 2.13
13 INT15580 Gene_expression of TCN2 16 0.44 7.59 1.97
14 INT41633 Positive_regulation of Positive_regulation of Cubn 2 0.48 0.1 1.89
15 INT25582 Regulation of Mtr 2 0.03 0.4 1.76
16 INT58034 Positive_regulation of TCN2 8 0.04 2.11 1.43
17 INT47446 Regulation of Localization of Mtr 1 0.05 0.07 1.42
18 INT117014 Binding of TCN2 11 0.13 1.6 1.38
19 INT112068 Gene_expression of GIF 8 0.58 2.6 1.35
20 INT9217 Negative_regulation of MTR 17 0.58 1.13 1.32
21 INT2595 Binding of Mtr 1 0.29 0 1.24
22 INT257952 Positive_regulation of CUBN 1 0.07 0.61 1.22
23 INT44498 Localization of Cubn 2 0.34 0.38 1.19
24 INT41333 Negative_regulation of Positive_regulation of Cubn 2 0.15 0.47 1.12
25 INT28244 Protein_catabolism of TCN1 7 0.96 0.89 1.11
26 INT47131 Negative_regulation of Localization of Mtr 1 0.41 0 1.06
27 INT157361 Localization of MTR 2 0.31 1.4 1.05
28 INT24750 Negative_regulation of Mtr 1 0.22 0.06 1.04
29 INT155156 Gene_expression of TCN1 13 0.58 3.25 0.99
30 INT44500 Regulation of Localization of Cubn 1 0.20 0 0.75
31 INT132281 Binding of TCN1 2 0.33 0.95 0.74
32 INT257951 Localization of CUBN 1 0.07 0 0.71
33 INT24584 Positive_regulation of MTR 4 0.44 0.07 0.7
34 INT239232 Positive_regulation of Gene_expression of TCN2 1 0.01 2.17 0.7
35 INT257948 Binding of CUBN 1 0.05 0 0.7
36 INT13894 Regulation of Negative_regulation of Cubn 1 0.13 0.09 0.63
37 INT10007 Regulation of Gene_expression of Mtr 2 0.23 1.17 0.61
38 INT14109 Positive_regulation of Mtr 1 0.03 0.49 0.6
39 INT124269 Binding of Cubn 1 0.28 0.2 0.59
40 INT128569 Regulation of Positive_regulation of Cubn 1 0.09 0 0.49
41 INT126119 Positive_regulation of TCN1 9 0.43 1.31 0.48
42 INT154450 Positive_regulation of Binding of TCN2 1 0.04 0 0.47
43 INT24583 Protein_catabolism of MTR 1 0.57 0 0.42
44 INT54952 Binding of Mtr 1 0.03 0.58 0.37
45 INT143839 Negative_regulation of TCN1 2 0.27 0.28 0.33
46 INT26194 Regulation of MTR 1 0.19 1.1 0.33
47 INT166893 Negative_regulation of Gene_expression of Mtr 1 0.03 0.57 0.33
48 INT282213 Negative_regulation of Regulation of Mtr 1 0.01 0.82 0.27
49 INT165643 Regulation of TCN1 4 0.39 0.56 0.22
50 INT70913 Gene_expression of MTR 2 0.12 0.44 0.21
51 INT223333 Negative_regulation of Gene_expression of MTR 1 0.07 0.16 0.16
52 INT140682 Positive_regulation of GIF 4 0.49 0.87 0.15
53 INT55773 Binding of MTR 2 0.30 0.74 0.14
54 INT70523 Regulation of TCN2 1 0.14 0.17 0.09
55 INT12251 Regulation of Negative_regulation of Mtr 1 0.19 0 0.09
56 INT91702 Negative_regulation of GIF 4 0.42 1.58 0.08
57 INT239230 Regulation of Gene_expression of TCN2 1 0.01 0.46 0.08
58 INT55772 Negative_regulation of Negative_regulation of MTR 1 0.41 0 0.07
59 INT63309 Localization of GIF 2 0.78 1.14 0.06
60 INT332590 Negative_regulation of Gene_expression of TCN2 1 0.05 1.2 0.06
61 INT288754 Negative_regulation of Positive_regulation of Mtr 1 0.11 0.1 0.05
62 INT245976 Localization of TCN1 1 0.07 0.16 0.04
63 INT288765 Positive_regulation of Negative_regulation of Mtr 1 0.12 0.09 0.04
64 INT330470 Regulation of Positive_regulation of TCN1 1 0.17 0.23 0.03
65 INT245958 Binding of GIF 2 0.36 0.45 0
66 INT354644 Gene_expression of CUBN 1 0.65 0.32 0
67 INT245963 Positive_regulation of Localization of GIF 1 0.06 0.07 0
68 INT47058 Positive_regulation of Negative_regulation of MTR 1 0.41 0 0
69 INT47059 Positive_regulation of Positive_regulation of MTR 1 0.44 0 0
70 INT325224 Positive_regulation of Gene_expression of TCN1 1 0.25 0 0
71 INT245959 Regulation of GIF 1 0.05 0.06 0
72 INT218490 Transcription of TCN2 1 0.01 0.31 0
73 INT245957 Negative_regulation of Gene_expression of GIF 1 0.05 0.25 0
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