GO:0031432

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Name titin binding
Categary Function
Go Slim No
Go Link GO:0031432
Unique Molecular Interactions 79
Total Molecular Interactions 165
Total Single Events 482
Pain Genes Associated 9

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for titin binding. They are ordered first by their pain relevance and then by number of times they were reported for titin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT97013 Negative_regulation of Binding of CALM3 and OPRM1 1 0.40 0 1.05
2 INT97011 Binding of CALM3 and OPRM1 1 0.35 0 1.05
3 INT309735 Binding of CALM3 and TRPV4 1 0.14 0 0.75
4 INT55262 Pigt Regulation of Calm2 1 0.07 0 0.47
5 INT55260 Cck Positive_regulation of Positive_regulation of Calm2 1 0.62 0 0.45
6 INT254460 Binding of Calm2 and Ca2 5 0.03 0.48 0.43
7 INT261058 Binding of CALM3 and CHR 1 0.04 0.14 0.38
8 INT265145 Calm2 Negative_regulation of Phosphorylation of Adrbk1 1 0.05 0.07 0.35
9 INT265146 Calm2 Negative_regulation of Phosphorylation of Prkcg 1 0.04 0.07 0.35
10 INT279705 CALM3 Regulation of TRPV4 2 0.08 0 0.33
11 INT265139 Binding of Calm2 and Cib1 1 0.00 0 0.33
12 INT170727 Binding of Grm5 and Calm2 1 0.01 0.13 0.28
13 INT261056 Binding of CALM3 and PLA2G6 1 0.09 0 0.27
14 INT261045 Negative_regulation of Binding of CALM3 and PLA2G6 1 0.10 0 0.27
15 INT261052 CALM3 Regulation of VIP 1 0.00 0.06 0.25
16 INT294487 Binding of Calm1 and Tcm 1 0.00 0.81 0.23
17 INT309729 CALM3 Regulation of TRPV1 1 0.04 0 0.22
18 INT7332 CALM3 Positive_regulation of ADCY1 1 0.46 0.13 0.21
19 INT226204 Nfkb1 Positive_regulation of Gene_expression of Trim63 1 0.04 0.65 0.14
20 INT261055 Negative_regulation of Binding of CALM3 and CHR 1 0.04 0 0.14
21 INT226208 Nfkb1 Positive_regulation of Protein_catabolism of Trim63 1 0.04 0.66 0.14
22 INT309743 Binding of CA2 and CALM3 1 0.04 0 0.13
23 INT252032 Binding of Calm1 and DXIum1 1 0.02 0.48 0.13
24 INT309747 CALM3 Regulation of TRPV5 1 0.03 0 0.13
25 INT309742 CALM3 Regulation of TRPV3 1 0.04 0 0.13
26 INT311111 Binding of Pcp4 and Calm2 1 0.11 0.57 0.13
27 INT309733 CALM3 Regulation of TRPV6 1 0.01 0 0.13
28 INT324831 Binding of TRIM63 and Ticam1 1 0.01 0.09 0.12
29 INT231118 Tlr4 Positive_regulation of Gene_expression of Trim63 1 0.20 0.67 0.11
30 INT309725 Gene_expression of CALM3 Negative_regulation of Positive_regulation of TRPC6 1 0.07 0 0.1
31 INT254456 Negative_regulation of Binding of Calm2 and Ca2 1 0.03 0 0.1
32 INT309738 CALM3 Positive_regulation of CA2 1 0.04 0 0.08
33 INT190529 IFNA1 Positive_regulation of Transcription of TRIM63 1 0.00 0.39 0.08
34 INT254459 Ca2 Positive_regulation of Calm2 1 0.03 0 0.08
35 INT309737 Binding of CALM3 and Positive_regulation of CA2 1 0.04 0 0.08
36 INT275105 CALM3 Positive_regulation of Prkcg 1 0.00 0 0.06
37 INT309748 CALM3 Regulation of CA2 1 0.02 0 0.06
38 INT309732 CALM3 Positive_regulation of Gene_expression of TRPV4 1 0.14 0 0.06
39 INT309752 CALM3 Positive_regulation of Gene_expression of CA2 1 0.04 0 0.06
40 INT309730 Binding of CALM3 and TYRP1 1 0.01 0 0.05
41 INT261057 Binding of CALM3 and CHGA 1 0.04 0.14 0.04
42 INT261042 Binding of CALM3 and VIP 1 0.00 0.14 0.04
43 INT170725 Binding of Calm2 and Pla2g3 1 0.00 0 0.03
44 INT259703 Binding of MYBPC3 and HELT 1 0.04 1.64 0
45 INT281609 Foxo3 Positive_regulation of Transcription of Trim63 1 0.29 0 0
46 INT309745 Negative_regulation of Binding of CALM3 and TRPV4 1 0.12 0 0
47 INT252031 DXIum1 Positive_regulation of Calm1 1 0.02 0 0
48 INT170723 Binding of Calm2 and Siah1a 1 0.24 0 0
49 INT303342 Binding of NPAT and TCAP 1 0.40 0 0
50 INT303404 Binding of TCAP and Jag1 1 0.39 0 0
51 INT309746 CALM3 Positive_regulation of CAMK2G 1 0.02 0 0
52 INT309734 Binding of CALM3 and RPLP2 1 0.01 0 0
53 INT170726 Negative_regulation of Binding of Grm5 and Calm2 1 0.01 0 0
54 INT170720 Negative_regulation of Binding of Calm2 and Pla2g3 1 0.00 0 0
55 INT281608 Foxo4 Positive_regulation of Transcription of Trim63 1 0.27 0 0
56 INT286773 Binding of Tusc2 and TRIM63 1 0.02 0.34 0
57 INT309753 Binding of CALM3 and GOPC 1 0.04 0 0
58 INT309741 Binding of C2 and CALM3 1 0.03 0 0
59 INT272197 Binding of CAPN3 and DYSF 1 0.42 0.38 0
60 INT281607 Foxo1 Positive_regulation of Transcription of Trim63 1 0.27 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for titin binding. They are ordered first by their pain relevance and then by number of times they were reported in titin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT97018 Binding of CALM3 7 0.43 0.13 5.82
2 INT29326 Gene_expression of Calm1 17 0.67 3.71 4.53
3 INT55259 Negative_regulation of Calm2 9 0.49 1.87 3.4
4 INT136651 Binding of Calm2 30 0.42 1.09 3.11
5 INT37899 Positive_regulation of Calm2 10 0.58 0.53 2.27
6 INT121869 Negative_regulation of Calm1 2 0.57 0 1.83
7 INT7333 Localization of CALM3 4 0.72 0.4 1.55
8 INT37900 Regulation of Calm2 9 0.36 0.52 1.4
9 INT136650 Gene_expression of Calm2 18 0.51 1.57 1.39
10 INT97017 Regulation of Binding of CALM3 2 0.40 0 1.06
11 INT7338 Negative_regulation of CALM3 5 0.34 0.19 1
12 INT97014 Regulation of CALM3 1 0.55 0 0.97
13 INT97020 Negative_regulation of Regulation of CALM3 1 0.52 0 0.97
14 INT7335 Positive_regulation of CALM3 6 0.36 0.28 0.79
15 INT83375 Gene_expression of CALM3 3 0.58 1.57 0.78
16 INT57654 Negative_regulation of Negative_regulation of Calm2 1 0.28 0.16 0.73
17 INT272206 Gene_expression of CAPN3 4 0.77 3.83 0.7
18 INT160948 Negative_regulation of Gene_expression of Calm1 1 0.15 0.99 0.62
19 INT39728 Regulation of TCAP 1 0.00 0 0.61
20 INT226164 Gene_expression of Trim63 5 0.68 4.77 0.49
21 INT170694 Phosphorylation of Calm2 3 0.35 0 0.43
22 INT37898 Positive_regulation of Positive_regulation of Calm2 1 0.40 0 0.41
23 INT203081 Gene_expression of Trim63 2 0.56 1.53 0.39
24 INT342958 Positive_regulation of Gene_expression of CAPN3 1 0.69 0.66 0.35
25 INT226170 Positive_regulation of Gene_expression of Trim63 5 0.44 3.96 0.31
26 INT160947 Regulation of Gene_expression of Calm1 1 0.16 0.5 0.31
27 INT328194 Transcription of Calm2 1 0.04 0 0.3
28 INT203067 Positive_regulation of Gene_expression of Trim63 2 0.50 0.92 0.28
29 INT252022 Phosphorylation of Calm1 1 0.55 0.55 0.27
30 INT252023 Positive_regulation of Calm1 1 0.44 0.79 0.27
31 INT261086 Positive_regulation of Negative_regulation of CALM3 1 0.16 0 0.26
32 INT137836 Negative_regulation of Binding of Calm2 2 0.51 0 0.23
33 INT188352 Regulation of Calm1 2 0.39 1.6 0.21
34 INT272202 Negative_regulation of CAPN3 4 0.59 0.99 0.2
35 INT329047 Positive_regulation of TRIM63 1 0.06 1.27 0.2
36 INT226171 Protein_catabolism of Trim63 1 0.24 1.85 0.19
37 INT342960 Regulation of CAPN3 1 0.45 0.39 0.18
38 INT342959 Protein_catabolism of CAPN3 1 0.87 0.41 0.16
39 INT252026 Localization of Calm1 1 0.65 0.55 0.15
40 INT252021 Binding of Calm1 1 0.42 0.69 0.13
41 INT328191 Negative_regulation of Transcription of Calm2 1 0.02 0 0.13
42 INT281604 Negative_regulation of Gene_expression of Trim63 1 0.42 0.65 0.13
43 INT7334 Positive_regulation of Localization of CALM3 1 0.42 0.17 0.12
44 INT324792 Regulation of TRIM63 1 0.03 0.09 0.12
45 INT226183 Negative_regulation of Gene_expression of Trim63 1 0.12 0.68 0.12
46 INT281585 Binding of Trim63 1 0.27 0.59 0.12
47 INT311134 Negative_regulation of Gene_expression of Calm2 1 0.27 0.73 0.1
48 INT309767 Negative_regulation of Gene_expression of CALM3 1 0.13 0 0.1
49 INT309756 Positive_regulation of Gene_expression of CALM3 1 0.14 0 0.09
50 INT170713 Positive_regulation of Gene_expression of Calm2 4 0.39 0.36 0.06
51 INT342956 Positive_regulation of Negative_regulation of CAPN3 1 0.46 0.16 0.06
52 INT170692 Regulation of Gene_expression of Calm2 1 0.25 0.36 0.06
53 INT281595 Regulation of Binding of Trim63 1 0.33 0.32 0.05
54 INT190625 Transcription of TRIM63 1 0.02 0.27 0.05
55 INT226168 Regulation of Protein_catabolism of Trim63 1 0.12 0.56 0.05
56 INT222291 Positive_regulation of Trim63 3 0.50 0.94 0.04
57 INT281601 Regulation of Trim63 1 0.14 0.17 0.04
58 INT281592 Regulation of Gene_expression of Trim63 1 0.33 0.17 0.04
59 INT259711 Phosphorylation of MYBPC3 1 0.74 1.31 0.03
60 INT222292 Transcription of Trim63 3 0.52 0.32 0
61 INT254441 Localization of Calm2 2 0.13 0 0
62 INT222294 Positive_regulation of Transcription of Trim63 2 0.36 0.17 0
63 INT281593 Regulation of Positive_regulation of Trim63 1 0.33 0 0
64 INT272203 Binding of CAPN3 1 0.37 0.23 0
65 INT351072 Binding of Trim63 1 0.04 0.62 0
66 INT342957 Positive_regulation of CAPN3 1 0.43 0.18 0
67 INT231101 Transcription of Trim63 1 0.46 0 0
68 INT351075 Positive_regulation of Binding of Trim63 1 0.05 0.68 0
69 INT170689 Positive_regulation of Binding of Calm2 1 0.28 0 0
70 INT170707 Regulation of Binding of Calm2 1 0.15 0 0
71 INT298111 Positive_regulation of Localization of Calm2 1 0.09 0 0
72 INT261087 Negative_regulation of Positive_regulation of CALM3 1 0.12 0 0
73 INT281584 Regulation of Transcription of Trim63 1 0.20 0 0
74 INT342954 Positive_regulation of Positive_regulation of CAPN3 1 0.43 0.1 0
75 INT281590 Negative_regulation of Trim63 1 0.31 0.08 0
76 INT309760 Negative_regulation of Binding of CALM3 1 0.13 0 0
77 INT342961 Negative_regulation of Gene_expression of CAPN3 1 0.43 0.1 0
78 INT303380 Protein_catabolism of TCAP 1 0.64 0 0
79 INT303361 Positive_regulation of Trim63 1 0.16 0.29 0
80 INT281586 Protein_catabolism of Trim63 1 0.47 0.06 0
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