GO:0031490

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Name chromatin DNA binding
Categary Function
Go Slim No
Go Link GO:0031490
Unique Molecular Interactions 233
Total Molecular Interactions 320
Total Single Events 1568
Pain Genes Associated 27

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for chromatin DNA binding. They are ordered first by their pain relevance and then by number of times they were reported for chromatin DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT93470 Notch1 Positive_regulation of Localization of Prkcg 2 0.09 0.31 1.65
2 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
3 INT144547 Binding of Mecp2 and Sin3a 1 0.40 0.87 0.76
4 INT253759 Hmgb1 Positive_regulation of Apex1 1 0.09 4.53 0.69
5 INT214595 Binding of FOXC1 and TIMP1 1 0.02 0.96 0.66
6 INT135361 Prr14 Positive_regulation of Mecp2 1 0.24 0.15 0.64
7 INT135363 Mecp2 Positive_regulation of Mbd1 1 0.50 0.15 0.64
8 INT253760 Hmgb1 Positive_regulation of Gene_expression of Apex1 1 0.10 3.53 0.58
9 INT131810 Nfkb1 Negative_regulation of Localization of Apex1 1 0.01 0.52 0.57
10 INT141362 EP300 Negative_regulation of Transcription of IL2 1 0.17 0 0.56
11 INT167651 Binding of Oprd1 and Ep300 1 0.02 0.09 0.55
12 INT343913 Binding of FOS and Smad3 1 0.19 0.92 0.54
13 INT247265 Mecp2 Regulation of Fos 1 0.25 0.38 0.52
14 INT167652 Binding of Ep300 and Ngf 1 0.09 0.06 0.51
15 INT167655 Binding of Polr2f and Ep300 1 0.01 0.06 0.51
16 INT135360 Binding of Mecp2 and Aadac 1 0.03 0.19 0.51
17 INT253770 Hmgb1 Positive_regulation of Localization of Apex1 1 0.08 0.71 0.49
18 INT165078 Binding of CTSB and Notch1 1 0.00 1.08 0.48
19 INT195552 Binding of Rela and Ep300 1 0.03 0.2 0.45
20 INT195554 Binding of Nfkb1 and Ep300 1 0.08 0.2 0.45
21 INT148377 PDP1 Positive_regulation of NOTCH1 1 0.44 0.64 0.44
22 INT148378 CP Positive_regulation of NOTCH1 1 0.11 0.64 0.44
23 INT280479 Binding of Mecp2 and Sin3a 1 0.00 1.54 0.35
24 INT44983 Ltc4s Positive_regulation of Rara 1 0.01 0.15 0.33
25 INT253766 Binding of Apex1 and Tlr4 1 0.03 0.53 0.32
26 INT253762 Binding of Apex1 and Hmgb1 1 0.09 1.29 0.32
27 INT44985 KNG1 Positive_regulation of Rara 1 0.00 0.15 0.32
28 INT128756 Binding of Esr1 and Foxc1 1 0.01 0.43 0.32
29 INT93833 Binding of Fos and Srf 1 0.00 0 0.3
30 INT93832 Binding of Elk1 and Srf 1 0.00 0 0.29
31 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29
32 INT214615 FOXC1 Positive_regulation of Gene_expression of Ang 1 0.01 0.29 0.28
33 INT214594 Binding of FOXC1 and IBD9 1 0.00 1.81 0.28
34 INT253765 Apex1 Positive_regulation of Hmgb1 1 0.09 1.27 0.24
35 INT256656 Binding of EP300 and HHIP 1 0.22 0 0.24
36 INT108842 RARA Positive_regulation of Gene_expression of GDF15 1 0.52 0.68 0.23
37 INT280475 Binding of Bdnf and Mecp2 1 0.11 0.92 0.22
38 INT280478 Mecp2 Negative_regulation of Gene_expression of Bdnf 1 0.13 0.94 0.22
39 INT297544 Pou3f3 Regulation of Notch1 1 0.06 0.41 0.2
40 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19
41 INT214591 FOXC1 Regulation of ICAM1 1 0.05 0.29 0.19
42 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19
43 INT280487 Negative_regulation of Binding of Mecp2 and Sin3a 1 0.00 0.77 0.18
44 INT318969 Mecp2 Regulation of Gene_expression of Bdnf 1 0.17 0.28 0.17
45 INT313023 Binding of Rara and Rxra 1 0.06 0.73 0.17
46 INT119267 Binding of EP300 and PPM1E 1 0.01 0.46 0.17
47 INT316052 Notch1 Regulation of Binding of Cd8a 1 0.01 0.86 0.15
48 INT316053 Notch1 Regulation of Binding of Cd4 1 0.02 0.86 0.15
49 INT316050 Binding of Notch1 and Regulation of Binding of Cd8a 1 0.01 0.86 0.15
50 INT316051 Binding of Notch1 and Regulation of Binding of Cd4 1 0.02 0.86 0.15
51 INT89763 Positive_regulation of APEX1 Positive_regulation of Positive_regulation of NR4A1 1 0.10 0.87 0.14
52 INT192106 Regulation of Binding of Rara and Retsat 1 0.00 0.83 0.13
53 INT247266 Binding of Mecp2 and Fos 1 0.30 0.18 0.13
54 INT247267 Binding of Egr1 and Mecp2 1 0.12 0.18 0.13
55 INT214593 Binding of FOXC1 and OAP 1 0.01 0.25 0.13
56 INT192105 Binding of Rara and Retsat 1 0.00 0.83 0.13
57 INT200304 Hdac2 Negative_regulation of Rorb 1 0.00 0 0.12
58 INT200346 Hdac2 Negative_regulation of Lhcgr 1 0.04 0 0.12
59 INT319731 Ep300 Positive_regulation of Binding of Rela 1 0.01 0.37 0.12
60 INT200347 Hdac2 Negative_regulation of Transcription of Lhcgr 1 0.04 0 0.12
61 INT319727 Binding of Crebbp and Ep300 1 0.02 0.36 0.11
62 INT319728 Positive_regulation of Binding of Crebbp and Ep300 1 0.03 0.36 0.11
63 INT262207 Binding of Nr1i2 and Ep300 1 0.14 1.08 0.11
64 INT192104 Binding of Rara and Rxrg 1 0.00 0.82 0.1
65 INT297546 Neurod1 Regulation of Notch1 1 0.05 0.2 0.1
66 INT278217 Binding of Ciita and Notch1 1 0.41 0.22 0.09
67 INT234222 PSEN1 Regulation of Gene_expression of NOTCH1 1 0.03 0 0.08
68 INT350700 Binding of Bcl6 and thd 1 0.00 0.21 0.08
69 INT287880 Binding of CREB1 and EP300 1 0.01 0 0.08
70 INT253764 Atp9a Positive_regulation of Apex1 1 0.00 0.39 0.08
71 INT247264 Mecp2 Positive_regulation of Gtf2i 1 0.02 0 0.08
72 INT201380 RARA Positive_regulation of Regulation of CPOX 1 0.07 0.21 0.08
73 INT350692 Binding of Bcl6 and Hand1 1 0.02 0.16 0.08
74 INT350720 Binding of Bcl6 and TBX21 1 0.07 0.22 0.08
75 INT248209 Camk2a Positive_regulation of Phosphorylation of Mecp2 1 0.52 0 0.08
76 INT331790 Binding of gr and Hdac2 1 0.01 0.74 0.07
77 INT331791 Akt1 Negative_regulation of Hdac2 1 0.03 0.8 0.07
78 INT331798 Regulation of Binding of gr and Hdac2 1 0.02 0.75 0.07
79 INT277615 Positive_regulation of Binding of ZNF238 and Hdac3 1 0.38 0.06 0.07
80 INT277614 Binding of ZNF238 and Hdac3 1 0.29 0.06 0.07
81 INT297246 Binding of Notch1 and Ncstn 1 0.04 0.32 0.07
82 INT327871 Binding of Notch1 and Postn 1 0.38 1.42 0.07
83 INT297244 Regulation of Binding of Notch1 and Ncstn 1 0.05 0.32 0.07
84 INT119266 CDKN1A Regulation of EP300 1 0.47 0.44 0.07
85 INT189557 Binding of NOTCH1 and ROBO4 1 0.01 0.22 0.06
86 INT225490 Med1 Positive_regulation of Ppara 1 0.12 0.26 0.06
87 INT311916 Smad3 Negative_regulation of Gene_expression of Mmp13 1 0.12 0.27 0.06
88 INT262173 Binding of Msx2 and Ep300 1 0.07 0.55 0.06
89 INT197727 Binding of RARA and Positive_regulation of PPARA 1 0.02 0.96 0.05
90 INT298806 Binding of Hdac3 and Rb1 1 0.02 0.77 0.05
91 INT319558 Positive_regulation of Creb1 Regulation of Srf 1 0.31 0.06 0.04
92 INT319559 Creb1 Regulation of Srf 1 0.28 0.06 0.04
93 INT261393 Binding of Nsdhl and Med1 1 0.02 1 0.04
94 INT353294 Binding of Smad2 and Smad3 1 0.15 0.08 0.04
95 INT349314 Binding of Notch1 and Notch3 1 0.11 0.67 0.04
96 INT353295 Binding of Smad3 and Smad4 1 0.17 0.08 0.04
97 INT225569 Binding of Ncoa6 and Ep300 1 0.18 0.63 0.04
98 INT291714 Binding of RARA and Rxra 3 0.07 0.2 0.03
99 INT347165 Binding of NOTCH1 and PAX5 1 0.05 0.86 0.03
100 INT249891 Binding of Atoh1 and Olig2 1 0.08 0.14 0.03
101 INT254852 Binding of Col7a1 and Smad3 1 0.01 0.57 0.03
102 INT327876 Postn Regulation of Gene_expression of Notch1 1 0.56 0.92 0.03
103 INT347163 NOTCH1 Positive_regulation of MSC 1 0.03 0.85 0.03
104 INT287814 Apex1 Positive_regulation of Gene_expression of Rnf128 1 0.03 0.15 0.03
105 INT347164 NOTCH1 Negative_regulation of Gene_expression of EBF1 1 0.03 0.85 0.03
106 INT182924 Binding of RARA and NR1H4 3 0.02 1.9 0
107 INT258529 Binding of JAG1 and NOTCH1 3 0.06 2.44 0
108 INT182918 Binding of DR1 and RARA 2 0.08 0 0
109 INT258528 Binding of NOTCH1 and DLL1 2 0.07 1.6 0
110 INT182949 Binding of RARA and VDR 1 0.20 0 0
111 INT225585 Regulation of Binding of Med1 and Tpr 1 0.00 0.07 0
112 INT291330 Binding of ENO1 and NOTCH1 1 0.03 1.33 0
113 INT269943 Sox17 Regulation of Binding of Smad3 1 0.37 0.12 0
114 INT254849 Negative_regulation of Rhoa Positive_regulation of Phosphorylation of Smad3 1 0.11 0.45 0
115 INT193946 Binding of Notch1 and Positive_regulation of Psen1 1 0.03 0.06 0
116 INT225562 Binding of Srcs4 and Ep300 1 0.02 0 0
117 INT132849 Homer1 Regulation of Srf 1 0.01 0.15 0
118 INT332881 Negative_regulation of Binding of Hdac3 and Ncor1 1 0.28 0.18 0
119 INT327870 Postn Positive_regulation of Gene_expression of Notch1 1 0.37 0.57 0
120 INT297245 Prnp Positive_regulation of Notch1 1 0.21 0.73 0
121 INT269937 Binding of Smad3 and Mgst1 1 0.09 0 0
122 INT315057 Binding of TOP1 and PAR4 1 0.16 1.23 0
123 INT327873 Postn Regulation of Notch1 1 0.41 0 0
124 INT269919 Sox17 Negative_regulation of Binding of Smad3 1 0.36 0 0
125 INT287875 EP300 Negative_regulation of HDAC9 1 0.04 0.51 0
126 INT190632 Binding of Srf and Yy1 1 0.20 0.14 0
127 INT291329 Binding of NOTCH1 and CERS1 1 0.06 1.42 0
128 INT356083 Binding of App and Notch1 1 0.02 0.2 0
129 INT193949 Alph1 Positive_regulation of Notch1 1 0.01 0.08 0
130 INT197313 Atoh1 Regulation of Neurod1 1 0.01 0.13 0
131 INT269924 Smad3 Regulation of Gene_expression of Cdkn2b 1 0.23 0.26 0
132 INT172604 Binding of EP300 and TP53 1 0.00 0 0
133 INT193950 Alph1 Positive_regulation of Positive_regulation of Notch1 1 0.01 0.07 0
134 INT269955 Positive_regulation of Binding of Smad3 and Sox17 1 0.39 0.05 0
135 INT254863 Tgfb1 Positive_regulation of Transcription of Smad3 1 0.03 0.23 0
136 INT197316 Hes1 Regulation of Atoh1 1 0.01 0.14 0
137 INT243107 Binding of Src and Ep300 1 0.06 0.17 0
138 INT182919 TGFBI Regulation of RARA 1 0.29 0.08 0
139 INT286115 Binding of APEX1 and Mutyh 1 0.10 0 0
140 INT172606 EP300 Positive_regulation of CREBBP 1 0.00 0.07 0
141 INT193948 Binding of Psen1 and Notch1 1 0.02 0 0
142 INT342366 Binding of Rara and OSBPL1A 1 0.16 0 0
143 INT225590 Ncoa6 Regulation of Srf 1 0.08 0.21 0
144 INT254857 Tgfb1 Positive_regulation of Phosphorylation of Smad3 1 0.03 0.44 0
145 INT182961 Binding of RARA and KCNIP3 1 0.21 0.76 0
146 INT264727 Binding of Notch1 and Mir199b 1 0.00 0.86 0
147 INT225619 Binding of TARBP2 and Ep300 1 0.02 0 0
148 INT225481 Binding of Med1 and Acp5 1 0.16 0 0
149 INT235166 Binding of Hdac3 and Atxn1 1 0.02 0.28 0
150 INT269921 Binding of Smad3 and Scn4a 1 0.12 0 0
151 INT291682 Positive_regulation of Binding of RARA and TNFRSF10B 1 0.03 0 0
152 INT332894 Binding of Ahrr and Hdac3 1 0.01 0.08 0
153 INT269942 Sox17 Regulation of Smad3 1 0.37 0.12 0
154 INT218665 Olr811 Negative_regulation of Phosphorylation of Smad3 1 0.01 0.33 0
155 INT332896 Binding of Hdac3 and Ncor1 1 0.31 1.38 0
156 INT197315 Hes5 Regulation of Atoh1 1 0.00 0.14 0
157 INT264728 Mir199b Regulation of Notch1 1 0.01 0.85 0
158 INT269929 Binding of Cdkn2b and Smad3 1 0.18 0.89 0
159 INT291683 Binding of RARA and TNFRSF10B 1 0.03 0 0
160 INT269935 Binding of Smad3 and Scn5a 1 0.13 0 0
161 INT332878 Hdac3 Negative_regulation of Gene_expression of Arntl 1 0.42 0.17 0
162 INT269930 Binding of Smad3 and Sox17 1 0.40 1.16 0
163 INT172605 Positive_regulation of Binding of EP300 and TP53 1 0.00 0 0
164 INT234440 Binding of PROC and RARA 1 0.00 0.73 0
165 INT197306 Atoh1 Regulation of Neurod6 1 0.00 0.13 0
166 INT285770 Binding of NOTCH1 and Das 1 0.00 1.14 0
167 INT235167 Binding of Hdac3 and Ncor2 1 0.01 0.28 0
168 INT225541 Binding of Med1 and Tpr 1 0.00 0.07 0
169 INT207266 INS Negative_regulation of BCL6 1 0.29 0.08 0
170 INT322470 Binding of Bcl6 and Hif1a 1 0.06 0.52 0
171 INT264726 Binding of Notch1 and Gtf3a 1 0.00 1.68 0
172 INT356084 Binding of Notch1 and Ncstn 1 0.01 0.07 0
173 INT342362 Binding of Irs1 and Rara 1 0.15 0 0
174 INT326729 Foxc1 Positive_regulation of Gene_expression of Ehf 1 0.23 0.26 0
175 INT305632 Binding of BCL6 and MME 1 0.00 1.37 0
176 INT285769 Das Regulation of NOTCH1 1 0.00 0.78 0
177 INT243111 Binding of Crebbp and Ep300 1 0.16 0.17 0
178 INT225543 Binding of D0Nrs1 and Ep300 1 0.01 0 0
179 INT332892 Ncor1 Positive_regulation of Hdac3 1 0.45 0.18 0
180 INT352689 VAX2 Positive_regulation of HIST1H1B 1 0.01 0.59 0
181 INT193947 Notch1 Positive_regulation of Alph1 1 0.01 0.07 0
182 INT291333 Binding of CSHL1 and NOTCH1 1 0.05 1.16 0
183 INT225563 Binding of Tpr and Ep300 1 0.00 0 0
184 INT299456 Binding of Gabpa and Notch1 1 0.21 0.09 0
185 INT332879 Negative_regulation of Ncor1 Positive_regulation of Hdac3 1 0.28 0.18 0
186 INT264725 Binding of Hes1 and Notch1 1 0.03 0.84 0
187 INT225504 Binding of gr and Rara 1 0.02 0 0
188 INT269946 Binding of Smad3 and Gopc 1 0.08 0 0
189 INT268344 SMAD3 Positive_regulation of SMAD4 1 0.17 0.56 0
190 INT182948 KCNIP3 Regulation of Transcription of RARA 1 0.23 0.55 0
191 INT268508 MIR221 Positive_regulation of BCL6 1 0.03 1.36 0
192 INT258564 Binding of NOTCH1 and Crlf2 1 0.27 0.67 0
193 INT291681 Positive_regulation of Binding of DR1 and RARA 1 0.06 0 0
194 INT225622 Binding of STL and Ep300 1 0.01 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for chromatin DNA binding. They are ordered first by their pain relevance and then by number of times they were reported in chromatin DNA binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT9750 Positive_regulation of Rara 39 0.66 12.44 15.83
2 INT29988 Gene_expression of Mecp2 27 0.78 5.45 9.47
3 INT152668 Negative_regulation of EP300 13 0.38 7.78 9.03
4 INT11652 Gene_expression of Rara 30 0.58 24.96 6.98
5 INT144539 Phosphorylation of Mecp2 3 0.82 6.18 6.2
6 INT135359 Positive_regulation of Mecp2 4 0.70 4.35 6.05
7 INT123726 Positive_regulation of Notch1 23 0.70 7.2 5.65
8 INT131808 Localization of Apex1 2 0.16 13.46 4.61
9 INT2213 Regulation of EP300 10 0.54 4.72 4.5
10 INT69217 Gene_expression of Notch1 20 0.78 7.8 4.41
11 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28
12 INT90890 Positive_regulation of RARA 25 0.67 9.32 4.2
13 INT41878 Positive_regulation of EP300 13 0.61 5.24 3.95
14 INT122323 Positive_regulation of NOTCH1 36 0.70 35.63 3.7
15 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55
16 INT67726 Gene_expression of Notch1 36 0.75 9.77 3.54
17 INT139872 Regulation of Notch1 14 0.45 7.69 2.82
18 INT119025 Gene_expression of NOTCH1 46 0.75 31.32 2.64
19 INT4114 Gene_expression of Srf 9 0.70 6.11 2.63
20 INT171511 Gene_expression of EP300 14 0.53 4.17 2.29
21 INT50057 Regulation of Notch1 3 0.39 0.87 2.14
22 INT26123 Regulation of Ep300 6 0.23 1.22 2.03
23 INT171514 Binding of EP300 13 0.32 4.32 2.01
24 INT10447 Negative_regulation of Srf 3 0.40 0.95 1.98
25 INT26124 Negative_regulation of Ep300 5 0.37 1.25 1.94
26 INT144541 Negative_regulation of Gene_expression of Mecp2 3 0.42 1.43 1.9
27 INT140036 Positive_regulation of Gene_expression of Notch1 6 0.61 2 1.86
28 INT52633 Negative_regulation of Notch1 4 0.42 2.99 1.84
29 INT253756 Gene_expression of Apex1 1 0.14 7.47 1.84
30 INT247261 Negative_regulation of Mecp2 1 0.42 1.71 1.78
31 INT144538 Regulation of Phosphorylation of Mecp2 2 0.45 1.87 1.77
32 INT126457 Gene_expression of BCL6 34 0.66 22.45 1.75
33 INT172622 Localization of EP300 8 0.65 2.56 1.72
34 INT135355 Binding of Mecp2 4 0.37 0.83 1.72
35 INT192092 Positive_regulation of Gene_expression of Rara 8 0.32 4.41 1.68
36 INT116022 Positive_regulation of Positive_regulation of RARA 3 0.11 0.94 1.68
37 INT6830 Positive_regulation of Notch1 20 0.55 7.91 1.57
38 INT163381 Transcription of Notch1 2 0.69 0.41 1.52
39 INT144542 Positive_regulation of Phosphorylation of Mecp2 2 0.68 1.43 1.5
40 INT318963 Positive_regulation of Mecp2 5 0.50 1.78 1.49
41 INT272884 Gene_expression of Hdac2 19 0.43 14.55 1.48
42 INT67457 Binding of Rara 12 0.24 8.28 1.45
43 INT130098 Negative_regulation of NOTCH1 11 0.42 5.45 1.33
44 INT247263 Regulation of Mecp2 4 0.60 1.31 1.32
45 INT110784 Protein_catabolism of Notch1 8 0.21 2.32 1.31
46 INT81400 Binding of RARA 25 0.36 12.93 1.27
47 INT149295 Regulation of NOTCH1 10 0.13 4.26 1.22
48 INT280467 Negative_regulation of Mecp2 5 0.59 3.33 1.21
49 INT70821 Positive_regulation of Ep300 4 0.25 1.47 1.2
50 INT39711 Negative_regulation of FOXC1 4 0.41 4.29 1.2
51 INT110780 Localization of Notch1 2 0.06 0.47 1.19
52 INT81311 Gene_expression of FOXC1 9 0.44 3.46 1.18
53 INT272879 Negative_regulation of Hdac2 8 0.37 5.96 1.17
54 INT149292 Localization of NOTCH1 7 0.54 6.11 1.14
55 INT182985 Transcription of RARA 9 0.60 3.52 1.12
56 INT123727 Negative_regulation of Notch1 6 0.21 1.22 1.11
57 INT184720 Negative_regulation of Smad3 8 0.55 5.23 1.1
58 INT156427 Localization of FOXC1 2 0.73 1.36 1.07
59 INT10448 Positive_regulation of Srf 3 0.47 0.89 1.03
60 INT214609 Positive_regulation of Gene_expression of FOXC1 1 0.08 1.78 1
61 INT167650 Binding of Ep300 1 0.09 0.14 1
62 INT46334 Binding of FOXC1 2 0.36 2.66 0.99
63 INT43131 Regulation of FOXC1 3 0.36 1.09 0.98
64 INT69758 Negative_regulation of Positive_regulation of Rara 2 0.32 0.24 0.97
65 INT6833 Binding of Notch1 4 0.36 0.05 0.94
66 INT26531 Regulation of Srf 3 0.18 0.62 0.9
67 INT192090 Localization of Rara 6 0.46 4.15 0.89
68 INT48251 Regulation of Positive_regulation of Rara 2 0.33 0 0.88
69 INT120366 Negative_regulation of Rara 2 0.35 0.15 0.86
70 INT140794 Gene_expression of Smad3 22 0.64 9.41 0.83
71 INT48250 Regulation of Rara 3 0.29 2.47 0.83
72 INT48249 Positive_regulation of Positive_regulation of Rara 2 0.26 0 0.83
73 INT247262 Negative_regulation of Positive_regulation of Mecp2 1 0.42 0.85 0.8
74 INT212109 Localization of RARA 5 0.65 3.17 0.79
75 INT200250 Binding of Hdac2 6 0.22 2.97 0.76
76 INT45293 Transcription of Srf 2 0.47 0.79 0.76
77 INT74097 Gene_expression of Ep300 6 0.52 1.89 0.73
78 INT272883 Positive_regulation of Gene_expression of Hdac2 5 0.30 4.64 0.7
79 INT169421 Positive_regulation of FOXC1 4 0.49 2.42 0.7
80 INT318962 Negative_regulation of Gene_expression of Mecp2 2 0.43 0.5 0.7
81 INT183395 Localization of Mecp2 4 0.75 1.76 0.69
82 INT272886 Negative_regulation of Gene_expression of Hdac2 4 0.23 4.63 0.69
83 INT140037 Positive_regulation of Positive_regulation of Notch1 2 0.22 1.34 0.69
84 INT91398 Regulation of RARA 7 0.59 5.84 0.67
85 INT253750 Positive_regulation of Gene_expression of Apex1 1 0.10 1.43 0.64
86 INT280463 Binding of Mecp2 3 0.37 4 0.63
87 INT6831 Negative_regulation of Binding of Notch1 1 0.27 0 0.6
88 INT136920 Positive_regulation of Gene_expression of NOTCH1 12 0.49 8.25 0.59
89 INT45292 Negative_regulation of Transcription of Srf 1 0.06 0.65 0.59
90 INT236711 Gene_expression of Bcl6 15 0.30 12.98 0.58
91 INT234472 Positive_regulation of Transcription of RARA 2 0.44 0.13 0.58
92 INT110782 Negative_regulation of Localization of Notch1 1 0.03 0.33 0.56
93 INT149294 Regulation of Localization of NOTCH1 1 0.10 0.9 0.55
94 INT110785 Positive_regulation of Protein_catabolism of Notch1 1 0.05 0.33 0.55
95 INT247256 Negative_regulation of Phosphorylation of Mecp2 1 0.57 0.63 0.52
96 INT149297 Protein_catabolism of NOTCH1 2 0.15 0.87 0.51
97 INT201392 Negative_regulation of RARA 8 0.30 2.99 0.5
98 INT272868 Positive_regulation of Hdac2 3 0.27 2.15 0.5
99 INT247259 Positive_regulation of Gene_expression of Mecp2 1 0.68 0.13 0.46
100 INT158426 Binding of NOTCH1 10 0.36 7.95 0.45
101 INT280468 Positive_regulation of Localization of Mecp2 3 0.50 1.76 0.45
102 INT318964 Negative_regulation of Localization of Mecp2 1 0.43 0.53 0.43
103 INT182966 Regulation of Gene_expression of RARA 2 0.39 0.12 0.42
104 INT211982 Negative_regulation of Binding of Rara 1 0.28 0.24 0.42
105 INT207299 Binding of BCL6 6 0.30 3.5 0.41
106 INT145045 Gene_expression of Med1 29 0.65 5.37 0.39
107 INT218691 Phosphorylation of Smad3 1 0.28 3 0.38
108 INT280462 Positive_regulation of Phosphorylation of Mecp2 1 0.12 1.69 0.37
109 INT135356 Positive_regulation of Binding of Mecp2 1 0.50 0.1 0.36
110 INT157804 Phosphorylation of Smad3 18 0.77 8.15 0.35
111 INT187587 Binding of Ep300 11 0.35 2.37 0.34
112 INT343142 Negative_regulation of Regulation of Atoh1 1 0.41 0 0.33
113 INT182073 Binding of APEX1 4 0.12 1.72 0.32
114 INT121388 Positive_regulation of BCL6 2 0.28 2.71 0.32
115 INT272882 Positive_regulation of Binding of Hdac2 2 0.20 1.12 0.32
116 INT128754 Binding of Foxc1 1 0.01 0.43 0.32
117 INT343144 Regulation of Atoh1 1 0.43 0 0.32
118 INT181918 Positive_regulation of SMAD3 6 0.35 2.62 0.31
119 INT18821 Positive_regulation of Gene_expression of Srf 2 0.35 0.63 0.31
120 INT236166 Gene_expression of Atoh1 4 0.65 0.09 0.3
121 INT140795 Positive_regulation of Gene_expression of Smad3 3 0.48 3.16 0.3
122 INT258685 Regulation of Gene_expression of Notch1 2 0.40 1.45 0.3
123 INT235466 Localization of BCL6 3 0.27 5 0.29
124 INT338882 Regulation of Regulation of Mecp2 1 0.24 0.56 0.29
125 INT7610 Localization of Srf 3 0.67 0.98 0.27
126 INT248208 Phosphorylation of Mecp2 3 0.82 1.17 0.26
127 INT214611 Positive_regulation of Localization of FOXC1 1 0.07 0.34 0.26
128 INT262797 Regulation of Gene_expression of Smad3 2 0.34 2.27 0.25
129 INT325492 Regulation of Ep300 1 0.04 0.29 0.24
130 INT227426 Positive_regulation of Apex1 2 0.08 1.98 0.23
131 INT343143 Positive_regulation of Atoh1 1 0.42 0.09 0.23
132 INT316049 Regulation of Regulation of Notch1 1 0.03 0.92 0.23
133 INT10375 Negative_regulation of Gene_expression of RARA 1 0.57 0.97 0.22
134 INT130099 Negative_regulation of Positive_regulation of NOTCH1 4 0.43 2.56 0.21
135 INT247260 Regulation of Gene_expression of Mecp2 1 0.60 0.06 0.21
136 INT297241 Positive_regulation of Positive_regulation of Notch1 2 0.40 1.02 0.2
137 INT253752 Negative_regulation of Localization of Apex1 1 0.08 1.26 0.2
138 INT212787 Negative_regulation of Binding of EP300 1 0.13 0.53 0.2
139 INT256666 Regulation of Gene_expression of EP300 1 0.14 0.07 0.2
140 INT256661 Regulation of Positive_regulation of EP300 1 0.23 0.07 0.2
141 INT193945 Binding of Notch1 7 0.15 1.28 0.19
142 INT89772 Positive_regulation of APEX1 4 0.21 2.29 0.19
143 INT343141 Negative_regulation of Atoh1 1 0.41 0.1 0.19
144 INT325490 Positive_regulation of Ep300 1 0.03 0.22 0.19
145 INT352698 Gene_expression of VAX2 1 0.06 0.85 0.19
146 INT144881 Positive_regulation of Gene_expression of BCL6 5 0.43 1.6 0.18
147 INT130096 Positive_regulation of Positive_regulation of NOTCH1 2 0.50 1.15 0.18
148 INT157797 Negative_regulation of Phosphorylation of Smad3 3 0.40 0.95 0.17
149 INT298778 Phosphorylation of Hdac3 1 0.44 0.67 0.17
150 INT266991 Regulation of Hdac2 2 0.07 0.74 0.15
151 INT185203 Regulation of Regulation of FOXC1 1 0.16 0 0.15
152 INT298653 Positive_regulation of Binding of EP300 1 0.11 0.8 0.15
153 INT236693 Positive_regulation of Gene_expression of Bcl6 3 0.15 2.06 0.14
154 INT258953 Negative_regulation of Gene_expression of Bcl6 1 0.19 1.53 0.14
155 INT265376 Gene_expression of Hdac3 4 0.51 1.8 0.13
156 INT297239 Positive_regulation of Gene_expression of Notch1 2 0.40 1.31 0.13
157 INT158903 Gene_expression of Smad3 2 0.56 0.54 0.13
158 INT158890 Negative_regulation of Gene_expression of Smad3 1 0.42 0.13 0.13
159 INT192091 Regulation of Localization of Rara 1 0.04 0.67 0.13
160 INT338718 Positive_regulation of Localization of NOTCH1 1 0.04 0.6 0.13
161 INT182078 Gene_expression of APEX1 3 0.59 4.77 0.12
162 INT316042 Negative_regulation of Gene_expression of Notch1 1 0.27 1.7 0.12
163 INT172100 Binding of TOP1 2 0.14 1.31 0.11
164 INT258955 Localization of Bcl6 1 0.23 0.83 0.11
165 INT190501 Regulation of Apex1 1 0.12 0.32 0.1
166 INT331785 Negative_regulation of Gene_expression of Hdac3 1 0.04 0.86 0.1
167 INT273338 Protein_catabolism of Apex1 4 0.05 0.57 0.09
168 INT143835 Gene_expression of Foxc1 2 0.39 1.17 0.09
169 INT143833 Positive_regulation of Foxc1 2 0.42 1.02 0.09
170 INT143836 Negative_regulation of Foxc1 1 0.35 0.92 0.09
171 INT141999 Regulation of Gene_expression of NOTCH1 2 0.04 0.97 0.08
172 INT331786 Negative_regulation of Binding of Hdac2 1 0.11 1.2 0.08
173 INT350635 Transcription of Bcl6 1 0.09 0.16 0.08
174 INT350649 Negative_regulation of Transcription of Bcl6 1 0.06 0.16 0.08
175 INT214071 Negative_regulation of Transcription of RARA 3 0.37 1.77 0.07
176 INT327728 Regulation of Gene_expression of Notch1 2 0.27 0.73 0.07
177 INT182975 Phosphorylation of RARA 2 0.58 0.23 0.07
178 INT22789 Binding of Srf 1 0.37 0.07 0.07
179 INT22790 Positive_regulation of Binding of Srf 1 0.50 0.07 0.07
180 INT78478 Negative_regulation of TOP1 3 0.21 1.75 0.06
181 INT265317 Negative_regulation of Gene_expression of Smad3 2 0.41 0.9 0.06
182 INT190544 Transcription of Srf 1 0.19 0.43 0.06
183 INT190570 Localization of Srf 1 0.20 0.49 0.06
184 INT193845 Localization of Notch1 2 0.78 0.32 0.05
185 INT182080 Localization of APEX1 2 0.57 2.3 0.05
186 INT331784 Negative_regulation of Positive_regulation of Hdac2 1 0.11 0.52 0.05
187 INT214043 Positive_regulation of Localization of APEX1 1 0.38 0.64 0.05
188 INT193850 Regulation of Localization of Notch1 1 0.14 0.33 0.05
189 INT292252 Phosphorylation of EP300 1 0.20 0.55 0.05
190 INT262799 Localization of Smad3 6 0.56 2.09 0.04
191 INT265372 Localization of Hdac3 3 0.55 0.6 0.04
192 INT298336 Phosphorylation of Notch1 1 0.02 0.13 0.04
193 INT184722 Positive_regulation of Smad3 3 0.47 1.22 0.03
194 INT207276 Transcription of BCL6 3 0.45 0.64 0.03
195 INT350959 Transcription of NOTCH1 2 0.05 0.84 0.03
196 INT271419 Localization of SMAD3 2 0.11 0.13 0.03
197 INT265373 Regulation of Hdac3 2 0.17 1.1 0.03
198 INT225411 Positive_regulation of Srf 1 0.05 0.27 0.03
199 INT185206 Transcription of FOXC1 1 0.31 0 0.03
200 INT225413 Binding of Srf 1 0.10 0.27 0.03
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