GO:0031571

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Name mitotic cell cycle G1/S transition DNA damage checkpoint
Categary Process
Go Slim No
Go Link GO:0031571
Unique Molecular Interactions 384
Total Molecular Interactions 482
Total Single Events 3900
Pain Genes Associated 11

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitotic cell cycle G1/S transition DNA damage checkpoint. They are ordered first by their pain relevance and then by number of times they were reported for mitotic cell cycle G1/S transition DNA damage checkpoint. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT206768 TP53 Positive_regulation of Ltp 2 0.01 5.83 10.21
2 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
3 INT225158 Binding of CDK2 and CDKN1A 7 0.30 3.26 1.02
4 INT73461 PTPLA Positive_regulation of Transcription of TP53 1 0.06 0.99 0.96
5 INT330629 TP53 Negative_regulation of Gene_expression of Fos 1 0.30 1.76 0.94
6 INT330630 Binding of TP53 and Car1 1 0.23 1.56 0.86
7 INT97057 Bcl2l1 Regulation of Gene_expression of Trp53 1 0.36 0.51 0.83
8 INT97058 Cpz Regulation of Gene_expression of Trp53 1 0.27 0.57 0.83
9 INT101986 TP53 Positive_regulation of Gene_expression of GDF15 1 0.52 2.45 0.67
10 INT112870 Aap Positive_regulation of Gene_expression of Ccnd1 1 0.24 0.34 0.63
11 INT166402 CDKN1A Regulation of Gene_expression of TP53 1 0.27 0.83 0.61
12 INT164265 TGM7 Negative_regulation of CDK2 1 0.26 1.08 0.53
13 INT254200 Mif Regulation of Trp53 1 0.02 0.96 0.52
14 INT278105 Negative_regulation of TP63 Negative_regulation of Binding of P2RX7 1 0.00 0 0.51
15 INT302829 Mapkapk5 Positive_regulation of Trp53 1 0.07 0.81 0.43
16 INT163831 ERBB2 Positive_regulation of CCND1 1 0.03 0.82 0.38
17 INT242162 Binding of Ccnd1 and Wnt2 1 0.10 0.23 0.34
18 INT91814 Binding of TNF and TP53 1 0.14 2.2 0.32
19 INT166394 CDKN1B Regulation of Gene_expression of TP53 1 0.28 0.41 0.31
20 INT166396 IFI27 Regulation of Gene_expression of TP53 1 0.19 0.41 0.31
21 INT333917 MDM2 Positive_regulation of Protein_catabolism of Trp53 1 0.01 1.23 0.3
22 INT333918 HDAC1 Regulation of Trp53 1 0.03 1.24 0.3
23 INT163761 MDM2 Positive_regulation of Gene_expression of TP53 1 0.40 0.86 0.3
24 INT166952 LYRM4 Positive_regulation of Gene_expression of TP53 1 0.05 0.75 0.28
25 INT286042 Binding of Tp53 and Wwox 1 0.04 2.05 0.28
26 INT216127 EGR1 Regulation of Transcription of TP53 1 0.06 0.21 0.28
27 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28
28 INT306267 Binding of INCENP and TP53 1 0.02 0.83 0.27
29 INT216128 EGR1 Regulation of TP53 1 0.11 0.21 0.27
30 INT352931 Prkaca Regulation of TP53 1 0.13 1.01 0.26
31 INT352930 Prkaca Regulation of Phosphorylation of TP53 1 0.13 1.02 0.26
32 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
33 INT172975 Trp53 Positive_regulation of Cdkn1a 1 0.03 1.35 0.26
34 INT352893 PTGDS Regulation of TP53 1 0.16 1.02 0.26
35 INT125516 TP53 Regulation of GDF15 1 0.10 0.47 0.26
36 INT225160 Negative_regulation of Binding of CDK2 and CDKN1A 1 0.35 0 0.25
37 INT337086 Mif Negative_regulation of Localization of Trp53 1 0.16 1.64 0.25
38 INT337091 Mif Negative_regulation of Positive_regulation of Trp53 1 0.16 1.64 0.25
39 INT156879 Gene_expression of TP53 Negative_regulation of Positive_regulation of PDF 1 0.45 0.9 0.24
40 INT181900 TP53 Negative_regulation of Gene_expression of NOS1 1 0.03 0.94 0.24
41 INT156881 TP53 Positive_regulation of Positive_regulation of PDF 1 0.49 0.89 0.24
42 INT229177 IFRD1 Regulation of TP53 1 0.13 0.68 0.23
43 INT226902 Padi3 Regulation of Trp53 1 0.06 0.69 0.22
44 INT229178 TP53 Regulation of ICAM1 1 0.07 0.9 0.21
45 INT156882 Binding of TP53 and PDF 1 0.39 0.77 0.21
46 INT156880 TP53 Positive_regulation of Gene_expression of PDF 1 0.49 0.75 0.21
47 INT210887 Sst Positive_regulation of Gene_expression of Trp53 1 0.33 0.93 0.2
48 INT193787 Positive_regulation of CXCR4 Positive_regulation of Positive_regulation of TP53 1 0.03 0.71 0.19
49 INT142853 Binding of TP53 and WISP2 1 0.33 1.43 0.19
50 INT102804 NFKB1 Regulation of TP53 1 0.35 0.77 0.17
51 INT102803 NFKB1 Regulation of Gene_expression of TP53 1 0.35 0.77 0.17
52 INT327310 Binding of Ccnd1 and Elavl1 1 0.04 0.38 0.16
53 INT91812 Binding of FASLG and TP53 1 0.04 1.1 0.16
54 INT91811 Binding of FAS and TP53 1 0.21 1.1 0.16
55 INT327325 Binding of Hnrnpd and Ccnd1 1 0.03 0.38 0.16
56 INT266377 Binding of S100a11 and Trp53 1 0.02 0.89 0.15
57 INT311666 Binding of BCL2 and TP53 1 0.19 1.26 0.14
58 INT88410 BMP7 Negative_regulation of CDK2 1 0.35 0 0.14
59 INT103557 Binding of ERCC2 and TP53 1 0.40 1 0.13
60 INT201722 Myc Regulation of Gene_expression of Ccnd1 1 0.03 0.79 0.13
61 INT201762 JUP Regulation of Gene_expression of Ccnd1 1 0.03 0.8 0.13
62 INT132148 LTF Positive_regulation of TP53 1 0.44 0.56 0.13
63 INT103561 Binding of TP53 and Mc1r 1 0.03 1 0.13
64 INT196433 Cdk4 Negative_regulation of Ccnd1 1 0.10 1.17 0.13
65 INT342311 Binding of Tp53 and Positive_regulation of Gene_expression of BCL2 1 0.08 1.25 0.13
66 INT270667 Binding of Bcat1 and Prh1 1 0.01 0.89 0.12
67 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
68 INT184522 Positive_regulation of Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.95 0.11
69 INT184521 Ptger2 Regulation of Localization of Ccnd1 1 0.01 0.94 0.11
70 INT184520 Ptger2 Regulation of Ccnd1 1 0.00 0.94 0.11
71 INT266386 Binding of S100a1 and Trp53 1 0.03 0.64 0.1
72 INT193782 Binding of TP53 and SDF2L1 1 0.00 0.67 0.1
73 INT262522 Binding of Trp53 and Foxo4 1 0.05 0.7 0.1
74 INT310743 TP53 Regulation of BAX 1 0.09 1.11 0.1
75 INT326126 Binding of S100A1 and TP53 1 0.04 1.34 0.09
76 INT220511 Cav1 Negative_regulation of Transcription of Ccnd1 1 0.03 0.83 0.09
77 INT352611 Trp53 Negative_regulation of Localization of Gli1 1 0.23 1.2 0.09
78 INT302168 YWHAQ Regulation of TP53 1 0.01 0.41 0.09
79 INT265466 CSPG4 Regulation of Phosphorylation of TP53 1 0.09 0.15 0.09
80 INT185279 Binding of CCND1 and CDK4 4 0.13 2.05 0.08
81 INT185278 Binding of CCND1 and CDK6 3 0.13 1.62 0.08
82 INT246625 Sirt1 Positive_regulation of Negative_regulation of Trp53 1 0.10 0.96 0.08
83 INT266394 Binding of S100a4 and Trp53 1 0.03 0.59 0.08
84 INT266390 Binding of S100a6 and Trp53 1 0.04 0.51 0.07
85 INT340567 Jun Positive_regulation of Gene_expression of Ccnd1 1 0.05 0.27 0.07
86 INT88411 Positive_regulation of PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
87 INT258021 Positive_regulation of Binding of CDK2 and CDKN1A 1 0.11 0.84 0.07
88 INT88408 PDGFA Positive_regulation of CDK2 1 0.11 0 0.07
89 INT215693 Trib3 Regulation of Gene_expression of Ccnd1 1 0.00 0.09 0.07
90 INT245296 Trp53 Regulation of Gadd45a 1 0.05 0.43 0.07
91 INT266398 Binding of S100b and Trp53 1 0.06 0.92 0.07
92 INT302143 TP53 Regulation of Positive_regulation of CASP3 1 0.01 0.69 0.06
93 INT302155 TP53 Regulation of Positive_regulation of CASP9 1 0.02 0.7 0.06
94 INT204074 Tp53 Positive_regulation of Cdkn1b 1 0.00 0.59 0.06
95 INT140291 ROS1 Positive_regulation of TP53 1 0.52 1.27 0.06
96 INT265459 Phosphorylation of TP53 Positive_regulation of Localization of CASP9 1 0.17 1.16 0.05
97 INT352618 Tpt1 Regulation of Trp53 1 0.06 0.54 0.05
98 INT286768 Binding of Trp53 and Tusc2 1 0.07 1.1 0.05
99 INT352621 Gli1 Negative_regulation of Trp53 1 0.32 0.56 0.05
100 INT181601 Binding of TP53 and WT1 1 0.30 0.9 0.05
101 INT265454 Phosphorylation of TP53 Positive_regulation of CASP9 1 0.17 1.16 0.05
102 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05
103 INT193788 ITIH4 Regulation of Phosphorylation of TP53 1 0.07 0.45 0.05
104 INT352612 Trp53 Negative_regulation of Cd44 1 0.24 1.01 0.04
105 INT316485 Stat3 Positive_regulation of Transcription of Ccnd1 1 0.23 1.27 0.04
106 INT348022 Binding of Jun and Trp53 1 0.07 0.46 0.04
107 INT172214 BAX Positive_regulation of TP53 1 0.09 0.37 0.04
108 INT329230 Negative_regulation of ATIC Positive_regulation of Trp53 1 0.00 0.58 0.04
109 INT207702 CCND1 Regulation of MSMB 1 0.22 0.69 0.04
110 INT329228 ATIC Positive_regulation of Trp53 1 0.01 0.58 0.04
111 INT352619 Bcl2l12 Negative_regulation of Trp53 1 0.27 0.94 0.04
112 INT352613 Binding of Trp53 and Bcl2l12 1 0.23 0.94 0.04
113 INT170457 RASGRP1 Regulation of TP53 1 0.02 0.58 0.04
114 INT201726 Mapk8 Positive_regulation of Positive_regulation of Trp53 1 0.00 0.41 0.04
115 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03
116 INT355036 CKAP4 Regulation of Positive_regulation of TP53 1 0.08 0.4 0.03
117 INT266903 Binding of Sod2 and Trp53 1 0.05 0 0.03
118 INT211873 TP53 Positive_regulation of Transcription of CD40 1 0.03 1.44 0.03
119 INT234625 TP53 Positive_regulation of IGFBP3 1 0.29 0.74 0.03
120 INT352624 Trp53 Negative_regulation of CEL 1 0.01 1.01 0.03
121 INT265464 CSPG4 Regulation of Gene_expression of TP53 1 0.09 0.23 0.03
122 INT338900 MYC Positive_regulation of Gene_expression of TP73 1 0.05 0.27 0.03
123 INT277745 Trib3 Regulation of Ccnd1 1 0.00 0.41 0.03
124 INT270462 Shh Positive_regulation of Ccnd1 1 0.10 0.6 0.03
125 INT314686 TP53 Regulation of Gene_expression of MDM2 1 0.21 0.96 0.03
126 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03
127 INT314677 TP53 Regulation of Positive_regulation of CDKN2A 1 0.27 0.97 0.03
128 INT276389 Binding of Trp53 and KRT20 1 0.01 0.97 0.03
129 INT302134 TP53 Positive_regulation of Transcription of CDKN1A 1 0.04 0.28 0.03
130 INT223067 IFI27 Negative_regulation of CCND1 1 0.05 0.65 0.03
131 INT314690 TP53 Regulation of Gene_expression of ZBTB7A 1 0.33 0.97 0.03
132 INT211872 TP53 Positive_regulation of CD40 1 0.03 1.44 0.03
133 INT223066 CDKN1A Negative_regulation of CCND1 1 0.04 0.66 0.03
134 INT289608 Binding of CDK2 and CCNE2 5 0.06 4.89 0
135 INT272517 Binding of Ccnd1 and Celf1 3 0.08 0.07 0
136 INT242015 Binding of Mdm2 and Trp53 3 0.16 5.74 0
137 INT144030 STAT3 Regulation of CCND1 2 0.09 1.05 0
138 INT201771 CDKN1A Positive_regulation of Localization of Ccnd1 1 0.04 0 0
139 INT219412 CDK2 Regulation of PCNA 1 0.20 0.11 0
140 INT348532 TP63 Positive_regulation of CASP3 1 0.04 0.55 0
141 INT352615 Binding of Mdm4 and Trp53 1 0.30 1.36 0
142 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0
143 INT315395 Regulation of Binding of IFNA1 and Tp53 1 0.00 0.46 0
144 INT304020 AR Regulation of TP53 1 0.24 1.11 0
145 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0
146 INT315221 Tpt1 Regulation of Positive_regulation of Trp53 1 0.33 1.04 0
147 INT203901 HIVEP1 Positive_regulation of Gene_expression of TP53 1 0.04 0.86 0
148 INT235649 TP73 Regulation of EFNA1 1 0.09 0.97 0
149 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0
150 INT333685 Binding of Trp53 and Hdac1 1 0.26 0.55 0
151 INT333688 Trp53 Positive_regulation of Bcl2 1 0.45 2.51 0
152 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0
153 INT333690 Hr Negative_regulation of Transcription of Trp53 1 0.23 0.51 0
154 INT217776 TP53 Regulation of MITF 1 0.00 1.28 0
155 INT334322 Binding of RB1 and TP53 1 0.34 2 0
156 INT342007 Mta1 Regulation of Trp53 1 0.15 0.15 0
157 INT325156 CDKN1B Negative_regulation of CDK2 1 0.49 0.11 0
158 INT179095 Myc Positive_regulation of Gene_expression of Trp53 1 0.43 0.83 0
159 INT315397 Binding of IFNA1 and Tp53 1 0.00 0.43 0
160 INT333689 Hr Positive_regulation of Protein_catabolism of Trp53 1 0.25 1.71 0
161 INT345489 TP53 Positive_regulation of PMAIP1 1 0.05 0.6 0
162 INT286044 Wwox Positive_regulation of Tp53 1 0.05 0.63 0
163 INT347162 MDM2 Negative_regulation of TP53 1 0.02 1.09 0
164 INT272518 Positive_regulation of Binding of Ccnd1 and Celf1 1 0.01 0 0
165 INT235645 TP53 Regulation of EPHA2 1 0.10 0.97 0
166 INT241256 TP53 Regulation of OPCML 1 0.12 1.31 0
167 INT305542 Binding of Rb1 and Trp53 1 0.00 0.9 0
168 INT352625 Trp53 Regulation of CEL 1 0.00 0.71 0
169 INT269948 Sox17 Positive_regulation of Gene_expression of Ccnd1 1 0.61 0.19 0
170 INT320714 Gene_expression of MDM2 Negative_regulation of TP53 1 0.16 0.88 0
171 INT333455 ATM Positive_regulation of TP53 1 0.18 0 0
172 INT269920 Positive_regulation of Binding of Ccnd1 and Qsox1 1 0.10 0 0
173 INT204234 Binding of CDKN2A and TP53 1 0.43 1.27 0
174 INT224291 Negative_regulation of ESR1 Positive_regulation of CCND1 1 0.16 0.07 0
175 INT177793 EGR1 Positive_regulation of Negative_regulation of TP53 1 0.18 0.44 0
176 INT284232 Binding of TP53 and HNRNPUL1 1 0.26 0.88 0
177 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0
178 INT306256 MDM2 Negative_regulation of Positive_regulation of TP53 1 0.23 0.44 0
179 INT278186 Binding of TP53 and GOPC 1 0.02 0.85 0
180 INT337708 Naf1 Regulation of Gene_expression of Tp53 1 0.09 0.22 0
181 INT348540 TP63 Positive_regulation of CASP8 1 0.03 0.55 0
182 INT250658 FOS Positive_regulation of CCND1 1 0.03 0.6 0
183 INT345337 Binding of TP53 and BCC1 1 0.11 1.05 0
184 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0
185 INT353437 Negative_regulation of Trp53 Positive_regulation of Gene_expression of Cdkn2a 1 0.24 0.59 0
186 INT268513 MIR34A Regulation of Gene_expression of TP53 1 0.00 0.9 0
187 INT145338 Binding of PYGO1 and Positive_regulation of Transcription of CCND1 1 0.07 0 0
188 INT235647 TP63 Regulation of EPHA2 1 0.15 0.97 0
189 INT172604 Binding of EP300 and TP53 1 0.00 0 0
190 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0
191 INT269925 Binding of Ccnd1 and Qsox1 1 0.07 0 0
192 INT225564 Ncoa6 Regulation of Trp53 1 0.04 0.93 0
193 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0
194 INT352617 Mdm2 Positive_regulation of Positive_regulation of Trp53 1 0.20 2.56 0
195 INT337639 TP53 Regulation of Gene_expression of MIR34A 1 0.08 1.19 0
196 INT338197 CCND1 Negative_regulation of AR 1 0.24 0 0
197 INT350983 TP53 Regulation of VEGFA 1 0.03 0.61 0
198 INT269949 Sox17 Positive_regulation of Ccnd1 1 0.61 0.96 0
199 INT276380 Binding of PIM1 and Trp53 1 0.01 0.66 0
200 INT337680 Binding of TP53 and Scrib 1 0.03 1.6 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitotic cell cycle G1/S transition DNA damage checkpoint. They are ordered first by their pain relevance and then by number of times they were reported in mitotic cell cycle G1/S transition DNA damage checkpoint. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8
2 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71
3 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65
4 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02
5 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64
6 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85
7 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49
8 INT102572 Gene_expression of Ccnd1 79 0.69 56.37 7.34
9 INT97055 Positive_regulation of Gene_expression of Trp53 51 0.70 45.7 7.25
10 INT93359 Positive_regulation of Trp53 90 0.70 69.77 6.24
11 INT75501 Gene_expression of CCND1 90 0.76 60.86 5.93
12 INT112545 Phosphorylation of TP53 28 0.80 14.13 5.93
13 INT60585 Regulation of TP53 59 0.59 54.55 5.21
14 INT109972 Phosphorylation of Trp53 13 0.80 6.15 4.68
15 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62
16 INT57749 Negative_regulation of Gene_expression of TP53 39 0.56 36.79 4.45
17 INT88414 Negative_regulation of CDK2 30 0.57 18.4 3.96
18 INT71602 Negative_regulation of Trp53 84 0.59 67.77 3.68
19 INT93399 Gene_expression of Ccnd1 38 0.58 21 3.65
20 INT12844 Binding of TP63 15 0.47 10.57 3.38
21 INT75500 Negative_regulation of Gene_expression of CCND1 21 0.57 11.59 3.24
22 INT8103 Binding of TP53 46 0.44 40.2 2.96
23 INT90875 Negative_regulation of CCND1 31 0.42 26.22 2.66
24 INT109969 Positive_regulation of Phosphorylation of Trp53 1 0.45 2.18 2.66
25 INT109968 Positive_regulation of Positive_regulation of Trp53 6 0.47 3.57 2.51
26 INT55952 Transcription of TP53 16 0.61 12.14 2.36
27 INT93396 Positive_regulation of Gene_expression of Ccnd1 13 0.52 8.59 2.26
28 INT93398 Negative_regulation of Gene_expression of Ccnd1 5 0.44 2.61 2.12
29 INT104402 Positive_regulation of CCND1 15 0.70 11.77 2.08
30 INT125080 Positive_regulation of Positive_regulation of TP53 21 0.58 16.16 1.98
31 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94
32 INT65855 Localization of TP53 18 0.76 17.08 1.89
33 INT113345 Positive_regulation of Phosphorylation of TP53 8 0.66 6.11 1.8
34 INT112867 Positive_regulation of Gene_expression of Ccnd1 15 0.56 13.22 1.77
35 INT88412 Positive_regulation of CDK2 17 0.57 8.49 1.66
36 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62
37 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57
38 INT64233 Regulation of Trp53 35 0.62 27.11 1.53
39 INT120004 Transcription of Tp53 8 0.72 4.92 1.48
40 INT101990 Negative_regulation of Positive_regulation of TP53 5 0.33 3.69 1.42
41 INT162469 Positive_regulation of Protein_catabolism of TP53 5 0.52 5.48 1.42
42 INT172953 Binding of Trp53 33 0.37 20.76 1.41
43 INT93357 Regulation of Gene_expression of Trp53 15 0.62 13.4 1.41
44 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41
45 INT145221 Binding of Tp53 10 0.37 8.59 1.37
46 INT108327 Negative_regulation of Gene_expression of Ccnd1 18 0.38 14.36 1.31
47 INT174156 Localization of Trp53 16 0.72 13.52 1.18
48 INT116436 Negative_regulation of Phosphorylation of TP53 2 0.40 0.94 1.16
49 INT128987 Negative_regulation of Ccnd1 24 0.52 15.78 1.15
50 INT134661 Negative_regulation of Tp53 11 0.43 10.91 1.13
51 INT278117 Negative_regulation of TP63 5 0.32 3.38 1.13
52 INT144427 Transcription of Ccnd1 10 0.41 7.89 1.07
53 INT106735 Phosphorylation of CDK2 11 0.79 4.03 1.02
54 INT97052 Transcription of Trp53 12 0.64 6.52 1.01
55 INT59198 Regulation of Ccnd1 11 0.47 6.54 0.9
56 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87
57 INT109007 Positive_regulation of Ccnd1 23 0.53 9.5 0.86
58 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81
59 INT93356 Negative_regulation of Gene_expression of Trp53 28 0.53 20.61 0.8
60 INT44293 Regulation of TP63 6 0.24 2.88 0.76
61 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75
62 INT168245 Positive_regulation of Transcription of Tp53 2 0.70 2.63 0.75
63 INT162470 Negative_regulation of Protein_catabolism of TP53 1 0.32 1.24 0.74
64 INT105330 Gene_expression of CDK2 31 0.63 13.7 0.67
65 INT144432 Positive_regulation of Transcription of Ccnd1 4 0.36 2.36 0.63
66 INT93358 Negative_regulation of Positive_regulation of Trp53 9 0.41 3.95 0.6
67 INT53950 Phosphorylation of Tp53 8 0.61 9.4 0.6
68 INT113846 Negative_regulation of Positive_regulation of CDK2 1 0.48 0.39 0.6
69 INT128498 Regulation of CCND1 17 0.39 12.51 0.58
70 INT200797 Positive_regulation of Ptprv 4 0.14 3.19 0.58
71 INT146802 Positive_regulation of Ccnd1 4 0.38 1.37 0.53
72 INT154151 Positive_regulation of TP73 5 0.67 5.71 0.52
73 INT75498 Positive_regulation of Gene_expression of CCND1 21 0.68 19.4 0.51
74 INT258835 Localization of Ccnd1 3 0.53 2.7 0.5
75 INT286035 Negative_regulation of Gene_expression of Tp53 5 0.32 6.2 0.49
76 INT306741 Positive_regulation of Positive_regulation of TP63 2 0.05 1.16 0.49
77 INT146522 Negative_regulation of Positive_regulation of CCND1 3 0.30 2.04 0.48
78 INT163285 Negative_regulation of Phosphorylation of CDK2 2 0.32 0.52 0.48
79 INT278121 Negative_regulation of Negative_regulation of TP63 1 0.03 0 0.48
80 INT196424 Binding of Ccnd1 5 0.29 3.34 0.47
81 INT93400 Negative_regulation of Ccnd1 4 0.33 0.77 0.47
82 INT158643 Negative_regulation of Negative_regulation of CCND1 2 0.31 2.43 0.45
83 INT139976 Regulation of Tp53 7 0.44 6.49 0.39
84 INT218901 Negative_regulation of Ptprv 1 0.02 1.73 0.36
85 INT145220 Negative_regulation of Binding of Tp53 1 0.20 0.75 0.36
86 INT93355 Negative_regulation of Negative_regulation of Trp53 2 0.41 0.92 0.3
87 INT179089 Protein_catabolism of Trp53 8 0.90 6.52 0.29
88 INT186057 Binding of CCND1 8 0.31 5.92 0.26
89 INT166960 Positive_regulation of Negative_regulation of TP53 2 0.25 1.65 0.26
90 INT314729 Regulation of Localization of TP53 1 0.30 2.5 0.25
91 INT113989 Regulation of Gene_expression of CCND1 11 0.44 7.57 0.24
92 INT154150 Regulation of TP73 3 0.15 2.81 0.24
93 INT106733 Regulation of CDK2 6 0.44 4.76 0.23
94 INT179088 Positive_regulation of Regulation of Trp53 3 0.38 3.23 0.23
95 INT156886 Positive_regulation of Localization of TP53 1 0.48 0.87 0.23
96 INT154147 Gene_expression of TP73 7 0.34 3.97 0.19
97 INT146801 Regulation of Ccnd1 5 0.34 2.4 0.19
98 INT300284 Regulation of Phosphorylation of Tp53 1 0.16 1.51 0.17
99 INT337078 Negative_regulation of Localization of Trp53 1 0.20 1.3 0.17
100 INT163284 Negative_regulation of Gene_expression of CDK2 5 0.32 1.6 0.16
101 INT179086 Positive_regulation of Negative_regulation of Trp53 5 0.50 4.78 0.15
102 INT139201 Localization of TP63 4 0.32 2.56 0.15
103 INT145147 Negative_regulation of Gene_expression of TP63 4 0.42 2.91 0.15
104 INT125081 Positive_regulation of Binding of TP53 2 0.46 1.2 0.15
105 INT207805 Negative_regulation of Phosphorylation of Trp53 2 0.18 0.98 0.15
106 INT286749 Regulation of Localization of Trp53 1 0.06 1.39 0.15
107 INT154148 Negative_regulation of Gene_expression of TP73 3 0.21 1.89 0.14
108 INT145248 Negative_regulation of Negative_regulation of Ccnd1 1 0.23 0.47 0.13
109 INT168244 Regulation of Transcription of Tp53 1 0.33 0.57 0.13
110 INT196428 Negative_regulation of Binding of Ccnd1 1 0.14 1.17 0.13
111 INT201462 Binding of CDK2 12 0.39 5.2 0.12
112 INT196427 Negative_regulation of Transcription of Ccnd1 1 0.14 1.17 0.12
113 INT270632 Binding of Bcat1 1 0.34 0.88 0.12
114 INT169908 Localization of Ccnd1 7 0.57 2.68 0.11
115 INT184473 Regulation of Gene_expression of Ccnd1 5 0.40 2.73 0.1
116 INT146072 Binding of TP73 2 0.12 0.58 0.1
117 INT297456 Protein_catabolism of Tp53 1 0.11 0.72 0.1
118 INT201460 Positive_regulation of Gene_expression of CDK2 5 0.52 2.8 0.09
119 INT111139 Localization of Tp53 4 0.45 2.4 0.09
120 INT169428 Regulation of Gene_expression of CDK2 4 0.46 1.03 0.09
121 INT231496 Gene_expression of Ptprv 2 0.58 1.73 0.09
122 INT106732 Regulation of Phosphorylation of CDK2 2 0.44 0.8 0.09
123 INT302272 Localization of CDK2 2 0.30 1.09 0.09
124 INT215750 Transcription of Ccnd1 2 0.14 2.23 0.09
125 INT256569 Positive_regulation of Gene_expression of Ptprv 1 0.52 1.64 0.09
126 INT145375 Transcription of CCND1 7 0.52 3.86 0.07
127 INT136890 Protein_catabolism of TP63 2 0.56 1.17 0.07
128 INT352605 Regulation of Negative_regulation of Trp53 1 0.45 0.72 0.07
129 INT215731 Positive_regulation of Transcription of Ccnd1 1 0.13 0.1 0.06
130 INT231502 Binding of Ptprv 1 0.02 0.59 0.06
131 INT171421 Regulation of Positive_regulation of TP53 1 0.48 0.45 0.05
132 INT176590 Positive_regulation of Transcription of CCND1 1 0.17 0.27 0.05
133 INT315213 Negative_regulation of Binding of Trp53 1 0.32 0.11 0.05
134 INT311668 Regulation of Regulation of TP53 2 0.36 3.58 0.04
135 INT305536 Positive_regulation of Binding of Trp53 1 0.35 0.32 0.04
136 INT221830 Negative_regulation of Transcription of CCND1 3 0.18 2.15 0.03
137 INT217802 Regulation of Transcription of TP53 2 0.37 0.81 0.03
138 INT259061 Negative_regulation of Regulation of TP53 2 0.10 2.23 0.03
139 INT201468 Negative_regulation of Binding of CDK2 2 0.17 1.1 0.03
140 INT225226 Positive_regulation of Negative_regulation of Ccnd1 1 0.14 1.18 0.03
141 INT258832 Regulation of Transcription of Ccnd1 1 0.16 1.57 0.03
142 INT178927 Regulation of Gene_expression of Tp53 6 0.26 2.23 0
143 INT154149 Positive_regulation of Gene_expression of TP73 3 0.18 0.67 0
144 INT333669 Positive_regulation of Transcription of Trp53 3 0.45 2.33 0
145 INT209451 Regulation of Gene_expression of TP63 3 0.16 4.32 0
146 INT250698 Positive_regulation of Transcription of TP53 3 0.18 3.68 0
147 INT169427 Transcription of CDK2 2 0.09 0.42 0
148 INT113348 Negative_regulation of Binding of TP53 2 0.28 1.49 0
149 INT215727 Regulation of Gene_expression of Ccnd1 2 0.12 0.49 0
150 INT214913 Positive_regulation of Positive_regulation of Tp53 2 0.08 2.47 0
151 INT225215 Negative_regulation of Positive_regulation of Ccnd1 2 0.13 1.33 0
152 INT217820 Regulation of Negative_regulation of TP53 2 0.37 1.92 0
153 INT236700 Phosphorylation of Ccnd1 2 0.18 1.89 0
154 INT204059 Positive_regulation of Phosphorylation of Tp53 1 0.07 0.76 0
155 INT225220 Positive_regulation of Positive_regulation of Ccnd1 1 0.14 1.2 0
156 INT285901 Regulation of Transcription of CDK2 1 0.03 0.7 0
157 INT333668 Regulation of Protein_catabolism of Trp53 1 0.24 1.58 0
158 INT154146 Regulation of Gene_expression of TP73 1 0.16 0.26 0
159 INT305634 Localization of CCND1 1 0.07 2.69 0
160 INT276362 Protein_catabolism of CCND1 1 0.10 0.66 0
161 INT154152 Negative_regulation of TP73 1 0.13 0.21 0
162 INT297265 Positive_regulation of Positive_regulation of CCND1 1 0.07 0.94 0
163 INT341855 Positive_regulation of Positive_regulation of CDK2 1 0.06 0.51 0
164 INT333671 Regulation of Transcription of Trp53 1 0.24 0.83 0
165 INT289620 Regulation of Binding of CDK2 1 0.28 0.22 0
166 INT330350 Positive_regulation of Negative_regulation of CCND1 1 0.08 1.3 0
167 INT235459 Positive_regulation of Protein_catabolism of Ccnd1 1 0.13 0.49 0
168 INT276346 Regulation of Protein_catabolism of CCND1 1 0.04 0.66 0
169 INT179076 Negative_regulation of Protein_catabolism of Trp53 1 0.32 0.43 0
170 INT269909 Positive_regulation of Localization of Ccnd1 1 0.38 0 0
171 INT228997 Phosphorylation of Ccnd1 1 0.10 0.52 0
172 INT179957 Positive_regulation of Binding of Tp53 1 0.08 0.48 0
173 INT280555 Regulation of Binding of TP63 1 0.12 0.93 0
174 INT256567 Regulation of Ptprv 1 0.20 0.26 0
175 INT333663 Positive_regulation of Protein_catabolism of Trp53 1 0.45 0.84 0
176 INT333662 Negative_regulation of Transcription of Trp53 1 0.53 1.15 0
177 INT325169 Regulation of Negative_regulation of CDK2 1 0.34 0.05 0
178 INT225187 Positive_regulation of Binding of CDK2 1 0.56 0.87 0
179 INT302232 Negative_regulation of Binding of CCND1 1 0.11 0.84 0
180 INT223765 Negative_regulation of Positive_regulation of Tp53 1 0.07 1.69 0
181 INT201567 Positive_regulation of Protein_catabolism of TP63 1 0.23 1.17 0
182 INT305295 Regulation of Binding of TP53 1 0.39 1.09 0
183 INT235458 Protein_catabolism of Ccnd1 1 0.19 0.24 0
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