GO:0031575

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Name mitotic cell cycle G1/S transition checkpoint
Categary Process
Go Slim No
Go Link GO:0031575
Unique Molecular Interactions 282
Total Molecular Interactions 351
Total Single Events 2517
Pain Genes Associated 13

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for mitotic cell cycle G1/S transition checkpoint. They are ordered first by their pain relevance and then by number of times they were reported for mitotic cell cycle G1/S transition checkpoint. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT147107 TGFB1 Positive_regulation of Gene_expression of NGF 1 0.49 0.67 2.69
2 INT121698 HRAS Negative_regulation of Gene_expression of MMP3 1 0.06 0.5 2.6
3 INT302646 ARSA Positive_regulation of TGFB1 1 0.10 0.52 1.76
4 INT129717 TGFB1 Positive_regulation of Gene_expression of TNFRSF10D 3 0.38 4.29 1.71
5 INT147108 TGFB1 Positive_regulation of Gene_expression of FN1 4 0.47 1.01 1.63
6 INT247281 GLC1N Negative_regulation of HRAS 1 0.02 1.98 1.62
7 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
8 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
9 INT263048 Tgfb1 Positive_regulation of Gene_expression of Mmp2 1 0.13 0.81 1.07
10 INT129206 RYBP Positive_regulation of Gene_expression of TGFB1 1 0.00 1.04 0.95
11 INT166790 HRAS Negative_regulation of Gene_expression of PTGER1 1 0.01 1.46 0.95
12 INT73466 PTPLA Positive_regulation of Transcription of Hras1 1 0.21 0.98 0.95
13 INT121702 HRAS Negative_regulation of Positive_regulation of MMP1 1 0.06 0.2 0.9
14 INT121701 HRAS Negative_regulation of MMP1 1 0.06 0.2 0.89
15 INT121704 HRAS Negative_regulation of MMP3 1 0.06 0.19 0.89
16 INT121699 HRAS Negative_regulation of Gene_expression of MMP1 1 0.06 0.19 0.88
17 INT149559 Tgfb1 Positive_regulation of Gene_expression of Ccr5 1 0.00 0 0.88
18 INT149562 Tgfb1 Positive_regulation of CXCL10 1 0.00 0 0.88
19 INT149564 Tgfb1 Positive_regulation of Gene_expression of CXCL10 1 0.00 0 0.88
20 INT149560 Tgfb1 Positive_regulation of Ccr5 1 0.00 0 0.88
21 INT222985 CP Positive_regulation of Positive_regulation of TGFB1 1 0.00 1.57 0.85
22 INT149561 Tgfb1 Positive_regulation of Gene_expression of CCL2 1 0.00 0 0.83
23 INT149563 Tgfb1 Positive_regulation of CCL2 1 0.00 0 0.83
24 INT149558 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.00 0 0.82
25 INT149557 Tgfb1 Positive_regulation of Gene_expression of Ccl5 1 0.00 0 0.82
26 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77
27 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77
28 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76
29 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73
30 INT302642 Binding of ARSA and TGFB1 1 0.05 0.28 0.68
31 INT121966 HRAS Positive_regulation of RAC1 1 0.75 0.41 0.67
32 INT354913 VDR Positive_regulation of TGFB1 1 0.05 1.33 0.67
33 INT184193 HRAS Negative_regulation of Gene_expression of IL1B 1 0.00 1.12 0.65
34 INT247285 GLC1N Positive_regulation of Gene_expression of HRAS 1 0.02 1.3 0.61
35 INT137017 Tgfb1 Positive_regulation of Gene_expression of Acta2 1 0.00 0.84 0.61
36 INT335995 Il10 Negative_regulation of Tgfb1 1 0.06 0.83 0.57
37 INT56088 TGFB1 Positive_regulation of Transcription of SERPINE1 1 0.46 0.83 0.57
38 INT302645 ARSA Positive_regulation of Gene_expression of TGFB1 1 0.08 0.28 0.55
39 INT89144 TGFB1 Regulation of Gene_expression of Tcstv1 1 0.00 0.53 0.53
40 INT92918 Atp6v0a2 Negative_regulation of Gene_expression of Tgfb1 1 0.01 0.83 0.52
41 INT138151 Tgfb1 Regulation of IL1B 1 0.01 0.29 0.49
42 INT89145 TGFB1 Positive_regulation of Tcstv1 1 0.00 0.49 0.49
43 INT138153 Tgfb1 Regulation of IL6 1 0.01 0.29 0.49
44 INT132060 NBN Positive_regulation of Nos2 1 0.01 0.21 0.49
45 INT302643 ARSA Positive_regulation of Localization of TGFB1 1 0.08 0.12 0.49
46 INT138146 Tgfb1 Regulation of Mmp3 1 0.00 0.23 0.46
47 INT138149 Tgfb1 Regulation of Mmp2 1 0.00 0.23 0.46
48 INT164415 Tgfb1 Regulation of Crlf1 1 0.01 0.78 0.45
49 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
50 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
51 INT95563 HRAS Positive_regulation of TNF 1 0.03 0.7 0.45
52 INT169466 TGFB3 Positive_regulation of HRAS 1 0.03 0.89 0.43
53 INT247287 Gene_expression of GLC1N Regulation of Gene_expression of HRAS 1 0.02 0.56 0.42
54 INT75488 Binding of TGFB1 and Tgfbr1 1 0.23 0.78 0.41
55 INT75487 Binding of TGFB1 and Tgfbr2 1 0.31 0.83 0.41
56 INT351237 HRAS Regulation of CBL 1 0.00 0.48 0.4
57 INT92690 Tgfb1 Positive_regulation of Transcription of Fgf2 1 0.32 1.8 0.4
58 INT165567 Tnf Regulation of Gene_expression of Tgfb1 1 0.41 1.15 0.39
59 INT166788 HRAS Negative_regulation of Phosphorylation of NFKB1 1 0.08 0.5 0.39
60 INT336340 Glp2r Positive_regulation of Gene_expression of TGFB1 1 0.14 0.67 0.39
61 INT94853 TGFB1 Positive_regulation of Gene_expression of COL7A1 3 0.06 0.57 0.38
62 INT166792 Binding of CD44 and HRAS 3 0.12 1.49 0.37
63 INT257741 HRAS Negative_regulation of PTEN 1 0.15 1.06 0.35
64 INT257737 Positive_regulation of HRAS Negative_regulation of PTEN 1 0.17 1.07 0.35
65 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34
66 INT137018 Tgfb1 Positive_regulation of Pscs 1 0.01 0.43 0.34
67 INT137013 Tgfb1 Positive_regulation of Gene_expression of Pscs 1 0.01 0.43 0.34
68 INT225119 Foxm1 Regulation of Localization of TGFB1 1 0.01 0.63 0.34
69 INT333457 Binding of PPARA and TGFB1 1 0.04 0 0.34
70 INT56089 TGFB1 Regulation of SERPINE1 1 0.41 0.41 0.33
71 INT299549 Binding of TGFB1 and Egf 1 0.02 0.32 0.32
72 INT303105 CAMK4 Positive_regulation of Hras1 1 0.04 0.16 0.31
73 INT102849 Tgfb1 Positive_regulation of Gene_expression of Col3a1 1 0.04 0.85 0.3
74 INT166789 HRAS Regulation of Positive_regulation of NFKB1 1 0.05 0.31 0.3
75 INT56250 Binding of NBN and NCOR2 1 0.00 0 0.3
76 INT200640 Agtr2 Positive_regulation of Gene_expression of TGFB1 1 0.03 1.35 0.29
77 INT265467 HRAS Negative_regulation of Gene_expression of PTGS2 1 0.01 0.84 0.29
78 INT200639 Ace Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
79 INT200631 AGT Positive_regulation of Gene_expression of TGFB1 1 0.06 1.36 0.29
80 INT300552 Napa Positive_regulation of Gene_expression of TGFB1 1 0.01 0.88 0.29
81 INT137033 Tgfb1 Positive_regulation of Gene_expression of Col1a1 1 0.01 0.42 0.28
82 INT225101 TGFB1 Positive_regulation of Localization of COL1A1 1 0.03 0.59 0.28
83 INT225100 TGFB1 Positive_regulation of Gene_expression of COL1A1 1 0.04 0.59 0.28
84 INT137032 Il6 Positive_regulation of Localization of Tgfb1 1 0.04 0.51 0.27
85 INT83395 Binding of IL1RN and Tgfb1 1 0.01 0.17 0.26
86 INT139094 Csf2 Regulation of Tgfb1 1 0.42 0.58 0.26
87 INT271450 Thy1 Regulation of TGFB1 1 0.00 0.62 0.25
88 INT222981 TGFB1 Positive_regulation of Gene_expression of MMRN1 1 0.09 1.62 0.25
89 INT225098 ZNF630 Regulation of Localization of TGFB1 1 0.01 0.44 0.24
90 INT225105 ZNF630 Regulation of TGFB1 1 0.01 0.44 0.24
91 INT9720 Binding of TGFB1 and Egf 1 0.01 0 0.23
92 INT168710 Ifng Regulation of TGFB1 1 0.00 0.3 0.23
93 INT112596 Tgfb1 Negative_regulation of Negative_regulation of Mptp1 1 0.26 0.72 0.22
94 INT112595 Tgfb1 Negative_regulation of Gene_expression of Mptp1 1 0.27 0.72 0.22
95 INT89475 TGFB1 Positive_regulation of Gene_expression of PTHLH 3 0.61 3.64 0.21
96 INT346458 ROS1 Regulation of Localization of TGFB1 1 0.00 1.71 0.21
97 INT114905 TGFB1 Positive_regulation of Transcription of COL7A1 1 0.02 0.08 0.21
98 INT60347 COL2A1 Positive_regulation of Gene_expression of Hras 1 0.05 0.92 0.2
99 INT92691 Tgfb1 Positive_regulation of Ctgf 1 0.16 0.91 0.2
100 INT132054 NBN Positive_regulation of NOS1 1 0.00 0.08 0.2
101 INT92692 Tgfb1 Positive_regulation of Gene_expression of Fn1 1 0.27 0.91 0.2
102 INT92693 Tgfb1 Positive_regulation of Fgf2 1 0.32 0.9 0.2
103 INT280260 Tgfb1 Positive_regulation of Cxcr1 1 0.07 1.78 0.19
104 INT280270 Tgfb1 Positive_regulation of Gene_expression of Cxcr4 1 0.08 1.81 0.19
105 INT92694 Tgfb1 Positive_regulation of Positive_regulation of Col3a1 1 0.31 0.89 0.19
106 INT280275 Tgfb1 Positive_regulation of VEGFA 1 0.02 2.46 0.19
107 INT153457 Tgfb1 Positive_regulation of Gene_expression of Ctgf 1 0.13 1.15 0.19
108 INT280268 Tgfb1 Positive_regulation of Gene_expression of Vegfa 1 0.06 1.81 0.19
109 INT280266 Tgfb1 Positive_regulation of Vegfa 1 0.09 1.8 0.19
110 INT280261 Tgfb1 Positive_regulation of Gene_expression of Cxcr1 1 0.05 1.81 0.19
111 INT280267 Tgfb1 Positive_regulation of Cxcr4 1 0.11 2.45 0.19
112 INT280274 Tgfb1 Positive_regulation of Gene_expression of VEGFA 1 0.02 2.58 0.19
113 INT350718 Mir106b Regulation of TGFB1 1 0.00 0.42 0.18
114 INT350603 MIR25 Regulation of TGFB1 1 0.01 0.42 0.18
115 INT271451 TGFB1 Regulation of Serpine1 1 0.00 0.68 0.18
116 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18
117 INT184194 Binding of HRAS and SPAM1 1 0.00 0.26 0.17
118 INT179846 Il11 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
119 INT85334 Agtr2 Regulation of Regulation of Tgfb1 1 0.23 0.68 0.17
120 INT119264 Binding of RB1 and PPM1E 1 0.00 0.46 0.17
121 INT296037 TGFB1 Positive_regulation of IL17A 1 0.02 0 0.17
122 INT160083 TGFB1 Positive_regulation of Gene_expression of L1CAM 1 0.16 1.53 0.16
123 INT85333 Aqp1 Positive_regulation of Negative_regulation of Tgfb1 1 0.25 0.67 0.15
124 INT239323 Binding of Nr1h2 and Positive_regulation of Positive_regulation of Tgfb1 1 0.00 3.71 0.14
125 INT299550 TGFB1 Negative_regulation of Glul 1 0.01 0.34 0.14
126 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14
127 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14
128 INT254855 Agt Positive_regulation of Tgfb1 1 0.03 0.18 0.13
129 INT296031 Negative_regulation of TGFB1 Regulation of IL10 1 0.01 1.01 0.13
130 INT296027 TGFB1 Regulation of TH1L 1 0.02 1 0.13
131 INT299547 Negative_regulation of Binding of TGFB1 and Egf 1 0.02 0.1 0.13
132 INT69687 Tgfb1 Positive_regulation of Gene_expression of Il4 1 0.23 0 0.12
133 INT296080 TGFB1 Regulation of Hand2 1 0.01 1 0.12
134 INT247280 GLC1N Regulation of Gene_expression of HRAS 1 0.03 0.29 0.12
135 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12
136 INT296028 TGFB1 Regulation of IL10 1 0.01 1 0.12
137 INT69688 Tgfb1 Positive_regulation of Rel 1 0.50 0 0.12
138 INT173122 PPA1 Positive_regulation of HRAS 1 0.08 0.5 0.12
139 INT83370 Binding of HRAS and TP53 1 0.30 0.59 0.11
140 INT296038 TGFB1 Positive_regulation of Gene_expression of IL23R 1 0.02 0.05 0.11
141 INT299551 Regulation of Binding of TGFB1 and Egf 1 0.03 0.21 0.11
142 INT300313 TGFB1 Positive_regulation of Mapk14 1 0.01 1.5 0.11
143 INT293417 HRAS Regulation of IL11 1 0.00 1.17 0.1
144 INT293414 HRAS Regulation of PTHLH 1 0.00 1.18 0.1
145 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1
146 INT293408 HRAS Regulation of VEGFA 1 0.00 1.18 0.1
147 INT299555 Lifr Positive_regulation of Gene_expression of TGFB1 1 0.03 0.23 0.09
148 INT351426 SEPT5 Regulation of HRAS 1 0.00 0.7 0.09
149 INT351425 HRAS Regulation of SEPT5 1 0.00 0.7 0.09
150 INT293415 HRAS Positive_regulation of Localization of IL8 1 0.01 0.73 0.09
151 INT116789 Bsg Positive_regulation of Gene_expression of Tgfb1 1 0.00 0.18 0.09
152 INT127143 Binding of IL6 and TGFB1 2 0.01 0.16 0.08
153 INT238392 RB1 Regulation of E2F2 1 0.01 0.36 0.08
154 INT296041 Binding of TGFB1 and IL21 1 0.01 0.05 0.08
155 INT134832 TGFB1 Regulation of YAP1 1 0.16 0.68 0.08
156 INT134837 TGFB1 Regulation of SMAD7 1 0.34 0.68 0.08
157 INT134833 TGFB1 Regulation of Gene_expression of SMAD7 1 0.34 0.69 0.08
158 INT304330 TGFB1 Positive_regulation of ECM1 1 0.00 0.31 0.08
159 INT251232 Slc17a6 Positive_regulation of Tgfb1 1 0.03 0 0.08
160 INT134835 TGFB1 Regulation of Gene_expression of YAP1 1 0.49 0.69 0.08
161 INT134834 TGFB1 Positive_regulation of YAP1 1 0.55 0.81 0.08
162 INT273520 NBN Positive_regulation of CDIPT 1 0.06 0.82 0.08
163 INT245118 RBM45 Negative_regulation of CDKN2B 1 0.01 1.41 0.08
164 INT245119 Negative_regulation of RBM45 Negative_regulation of CDKN2B 1 0.01 1.43 0.08
165 INT134838 TGFB1 Positive_regulation of SMAD7 1 0.52 0.79 0.08
166 INT299548 Binding of TGFB1 and Lif 1 0.02 0 0.07
167 INT84751 Binding of HRAS and TWIST1 1 0.29 2.6 0.07
168 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07
169 INT84752 Binding of HRAS and DCPS 1 0.18 2.61 0.07
170 INT94851 TGFB1 Regulation of Gene_expression of COL7A1 1 0.03 0.06 0.06
171 INT204992 Hmmr Positive_regulation of Hras1 1 0.00 0.58 0.06
172 INT312228 INPP5K Regulation of TGFB1 1 0.06 0.08 0.05
173 INT343538 TGFB1 Positive_regulation of Gene_expression of GLI2 1 0.08 0.2 0.05
174 INT232206 Binding of Tgfb1 and Tnfsf11 1 0.02 0.52 0.04
175 INT235551 Gene_expression of Hras1 Negative_regulation of Positive_regulation of Apoe 1 0.03 0.57 0.04
176 INT232207 Binding of Tgfb1 and Tnfrsf11a 1 0.02 0.51 0.04
177 INT271452 Binding of TGFB1 and Eln 1 0.00 0.38 0.04
178 INT271449 Binding of TGFB1 and Lox 1 0.01 0.38 0.04
179 INT283720 Id2 Negative_regulation of Transcription of Cdkn2b 1 0.18 0.11 0.03
180 INT94157 CDCP1 Negative_regulation of RB1 1 0.02 0.92 0.03
181 INT94159 Positive_regulation of CDK1 Negative_regulation of RB1 1 0.45 0.93 0.03
182 INT273519 NBN Negative_regulation of YOD1 1 0.03 0.56 0.03
183 INT94158 CDK1 Negative_regulation of RB1 1 0.41 0.92 0.03
184 INT238393 Binding of E2F2 and RB1 3 0.04 0.24 0
185 INT340086 Binding of Tgfb1 and Cndp2 1 0.04 0.38 0
186 INT157811 TGFB1 Positive_regulation of Timp2 1 0.02 0.06 0
187 INT314865 Binding of Ltbp3 and Tgfb1 1 0.24 0.51 0
188 INT269932 Pcna Negative_regulation of Cdkn2b 1 0.09 0.07 0
189 INT215686 Cdkn2b Negative_regulation of Cdkn1c 1 0.01 0 0
190 INT172347 Eri1 Negative_regulation of Hras1 1 0.00 0.76 0
191 INT320959 Binding of HRAS and HMHA1 1 0.00 0.37 0
192 INT312221 Binding of TGFB1 and INPP5K 1 0.09 0 0
193 INT280262 Binding of Tgfb1 and Positive_regulation of Cxcr4 1 0.07 1.27 0
194 INT280276 Binding of Tgfb1 and Positive_regulation of VEGFA 1 0.02 1.27 0
195 INT121314 Tgfb1 Positive_regulation of Egfr 1 0.08 0.16 0
196 INT180855 TGFB1 Regulation of S100A10 1 0.06 0.69 0
197 INT188067 Rps6kb1 Regulation of Rps6 1 0.10 0.1 0
198 INT334322 Binding of RB1 and TP53 1 0.34 2 0
199 INT121316 Tgfb1 Negative_regulation of Xrcc1 1 0.06 0.08 0
200 INT273774 Binding of GPER and RB1 1 0.01 0.45 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for mitotic cell cycle G1/S transition checkpoint. They are ordered first by their pain relevance and then by number of times they were reported in mitotic cell cycle G1/S transition checkpoint. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18
2 INT48202 Gene_expression of Tgfb1 146 0.78 89.93 27.76
3 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23
4 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2
5 INT28216 Gene_expression of HRAS 173 0.75 93.97 20.78
6 INT12081 Localization of TGFB1 64 0.81 35.4 17.47
7 INT36336 Gene_expression of Tgfb1 41 0.77 21.82 14.53
8 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21
9 INT48203 Positive_regulation of Tgfb1 67 0.70 41.31 11.07
10 INT61120 Positive_regulation of Gene_expression of Tgfb1 34 0.70 21.15 6.93
11 INT48201 Localization of Tgfb1 27 0.59 13.65 5.54
12 INT48200 Transcription of Tgfb1 13 0.69 3.85 5.24
13 INT67868 Negative_regulation of Gene_expression of Tgfb1 18 0.43 14.27 5.16
14 INT89104 Binding of TGFB1 29 0.44 13.67 5.12
15 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54
16 INT89103 Regulation of Gene_expression of TGFB1 15 0.56 8.11 4.37
17 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28
18 INT20981 Binding of HRAS 42 0.48 24.49 4.23
19 INT36335 Localization of Tgfb1 19 0.79 7.06 4.17
20 INT69681 Negative_regulation of Tgfb1 42 0.51 22.28 4
21 INT80175 Positive_regulation of Gene_expression of HRAS 24 0.67 14.69 3.97
22 INT169475 Localization of HRAS 14 0.73 9.02 3.9
23 INT12083 Regulation of TGFB1 22 0.53 15.4 3.6
24 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53
25 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5
26 INT69216 Positive_regulation of Tgfb1 14 0.49 5.84 3.29
27 INT85147 Positive_regulation of Gene_expression of Tgfb1 12 0.46 7.29 3.24
28 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21
29 INT85149 Negative_regulation of Gene_expression of Tgfb1 11 0.42 4.73 3.19
30 INT112667 Negative_regulation of Tgfb1 9 0.58 2.72 2.97
31 INT9130 Negative_regulation of TGFB1 16 0.41 12.21 2.92
32 INT48199 Regulation of Tgfb1 17 0.54 9.57 2.74
33 INT62683 Negative_regulation of HRAS 19 0.57 7.93 2.65
34 INT48198 Binding of Tgfb1 29 0.47 19.59 2.46
35 INT73266 Gene_expression of RB1 50 0.70 29.09 2.31
36 INT12086 Regulation of Localization of TGFB1 4 0.43 1.65 2.09
37 INT76993 Regulation of HRAS 8 0.60 7.81 1.95
38 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84
39 INT86712 Regulation of Gene_expression of Tgfb1 2 0.15 2.03 1.65
40 INT84310 Regulation of Gene_expression of Tgfb1 7 0.29 6.6 1.63
41 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57
42 INT120071 Negative_regulation of Positive_regulation of Tgfb1 4 0.16 4.06 1.55
43 INT110992 Positive_regulation of Positive_regulation of TGFB1 4 0.50 3.01 1.51
44 INT184206 Protein_catabolism of HRAS 22 0.66 7.86 1.46
45 INT228040 Negative_regulation of Transcription of Tgfb1 1 0.04 0.49 1.42
46 INT12085 Positive_regulation of Localization of TGFB1 7 0.42 4.9 1.4
47 INT54587 Positive_regulation of Hras1 12 0.27 5.54 1.3
48 INT173892 Phosphorylation of TGFB1 8 0.79 2.63 1.3
49 INT63905 Regulation of RB1 13 0.62 12.67 1.28
50 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26
51 INT166171 Negative_regulation of Gene_expression of HRAS 5 0.07 3.98 1.11
52 INT120858 Positive_regulation of Localization of Tgfb1 7 0.68 1.46 1.03
53 INT247294 Regulation of Gene_expression of HRAS 1 0.04 1.8 1.02
54 INT73459 Transcription of Hras1 3 0.69 2.01 0.95
55 INT174188 Positive_regulation of Gene_expression of RB1 9 0.45 6.22 0.94
56 INT128717 Regulation of Tgfb1 6 0.61 1.94 0.94
57 INT123852 Negative_regulation of Positive_regulation of Tgfb1 3 0.28 1.69 0.94
58 INT139322 Negative_regulation of Negative_regulation of Tgfb1 1 0.53 0 0.86
59 INT85148 Transcription of Tgfb1 5 0.52 1.91 0.84
60 INT102848 Negative_regulation of Localization of Tgfb1 3 0.10 1.81 0.83
61 INT139323 Positive_regulation of Negative_regulation of Tgfb1 1 0.45 0 0.79
62 INT132127 Positive_regulation of Rps6 1 0.49 0.32 0.79
63 INT291617 Negative_regulation of Transcription of TGFB1 2 0.15 0.61 0.76
64 INT90790 Regulation of Localization of Tgfb1 2 0.29 0.46 0.75
65 INT36887 Regulation of Hras 2 0.44 0.76 0.72
66 INT337046 Positive_regulation of Binding of Tgfb1 1 0.30 1.1 0.69
67 INT121302 Positive_regulation of Localization of Tgfb1 5 0.07 1.91 0.67
68 INT114909 Negative_regulation of Localization of TGFB1 5 0.36 1.37 0.66
69 INT164957 Regulation of Gene_expression of Hras1 8 0.04 4.4 0.64
70 INT60343 Gene_expression of Hras 6 0.75 2.3 0.64
71 INT111891 Regulation of Transcription of Tgfb1 1 0.04 0.68 0.64
72 INT56251 Binding of NBN 4 0.38 3.16 0.62
73 INT114910 Negative_regulation of Positive_regulation of TGFB1 3 0.34 0.92 0.6
74 INT173891 Positive_regulation of Phosphorylation of TGFB1 4 0.49 2 0.59
75 INT138140 Protein_catabolism of Tgfb1 2 0.09 0.87 0.59
76 INT82167 Transcription of HRAS 4 0.67 3.8 0.53
77 INT69683 Positive_regulation of Transcription of Tgfb1 1 0.67 0 0.53
78 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51
79 INT100191 Gene_expression of Cdkn2b 1 0.65 0.06 0.51
80 INT92384 Regulation of Positive_regulation of HRAS 2 0.60 2.05 0.48
81 INT169470 Positive_regulation of Localization of HRAS 1 0.49 0.89 0.43
82 INT194993 Binding of RB1 15 0.37 10.96 0.4
83 INT60346 Positive_regulation of Gene_expression of Hras 4 0.42 1.56 0.4
84 INT132128 Positive_regulation of Phosphorylation of Rps6 1 0.49 0.16 0.4
85 INT132126 Phosphorylation of Rps6 1 0.80 0.16 0.39
86 INT225223 Localization of Cdkn2b 2 0.62 1.29 0.37
87 INT69680 Positive_regulation of Positive_regulation of Tgfb1 3 0.67 1.04 0.35
88 INT217379 Phosphorylation of Hras1 1 0.01 1.43 0.33
89 INT80065 Binding of Hras1 4 0.03 1.14 0.31
90 INT60342 Negative_regulation of Gene_expression of Hras 2 0.56 0.6 0.31
91 INT247292 Positive_regulation of Positive_regulation of HRAS 1 0.03 0.62 0.31
92 INT196426 Gene_expression of Cdkn2b 6 0.67 4.29 0.29
93 INT123541 Regulation of Gene_expression of Cdkn2b 1 0.26 0.06 0.26
94 INT82373 Positive_regulation of Regulation of HRAS 1 0.25 1.49 0.25
95 INT251228 Phosphorylation of Tgfb1 4 0.15 1.18 0.24
96 INT299545 Positive_regulation of Binding of TGFB1 2 0.06 1.08 0.22
97 INT188122 Negative_regulation of Hras1 12 0.02 8.38 0.21
98 INT174877 Localization of Hras1 4 0.04 0.97 0.2
99 INT348917 Negative_regulation of Protein_catabolism of HRAS 1 0.02 0.57 0.2
100 INT54586 Negative_regulation of Positive_regulation of Hras1 2 0.04 0 0.19
101 INT293677 Transcription of RB1 1 0.62 0.8 0.18
102 INT179828 Regulation of Positive_regulation of Rps6 1 0.04 0.07 0.17
103 INT85330 Positive_regulation of Regulation of Tgfb1 1 0.41 0.67 0.17
104 INT122201 Binding of Tgfb1 1 0.16 0.17 0.17
105 INT260849 Gene_expression of NBN 9 0.67 7.11 0.16
106 INT179805 Positive_regulation of Rps6 1 0.10 0.07 0.16
107 INT94168 Positive_regulation of Phosphorylation of RB1 12 0.60 6.6 0.15
108 INT133100 Negative_regulation of Localization of Tgfb1 2 0.28 1.48 0.15
109 INT60345 Regulation of Gene_expression of Hras 1 0.44 0.36 0.15
110 INT183490 Regulation of Hras1 7 0.04 1.65 0.13
111 INT197627 Localization of RB1 3 0.69 4.16 0.13
112 INT184200 Positive_regulation of Protein_catabolism of HRAS 1 0.01 0.45 0.13
113 INT314724 Regulation of Localization of RB1 1 0.15 1.25 0.13
114 INT231413 Negative_regulation of NBN 3 0.46 4.6 0.11
115 INT80063 Positive_regulation of Positive_regulation of Hras1 2 0.04 0.96 0.1
116 INT257732 Regulation of Positive_regulation of RB1 2 0.39 2.35 0.09
117 INT14738 Negative_regulation of Regulation of TGFB1 2 0.41 0.81 0.09
118 INT331623 Negative_regulation of Binding of TGFB1 1 0.02 1.02 0.08
119 INT245123 Gene_expression of CDKN2B 6 0.68 3.62 0.07
120 INT184989 Positive_regulation of CDKN2B 3 0.47 2.77 0.07
121 INT185030 Binding of CDKN2B 3 0.35 2.6 0.07
122 INT231412 Positive_regulation of NBN 3 0.55 3.13 0.07
123 INT139093 Regulation of Negative_regulation of Tgfb1 1 0.27 0.44 0.06
124 INT251230 Positive_regulation of Negative_regulation of Tgfb1 1 0.09 0 0.05
125 INT273525 Regulation of NBN 1 0.49 1.28 0.05
126 INT136115 Positive_regulation of Regulation of TGFB1 1 0.11 0.16 0.05
127 INT185020 Positive_regulation of Negative_regulation of TGFB1 1 0.43 0.44 0.04
128 INT180881 Regulation of Positive_regulation of TGFB1 2 0.32 1.32 0.03
129 INT314842 Phosphorylation of Cdkn2b 1 0.71 0.61 0.03
130 INT283688 Transcription of Cdkn2b 1 0.28 0.11 0.03
131 INT176092 Negative_regulation of Gene_expression of Hras1 5 0.03 3.31 0
132 INT174197 Negative_regulation of Gene_expression of RB1 4 0.47 4.25 0
133 INT271907 Phosphorylation of Rps6 4 0.09 0.67 0
134 INT284972 Negative_regulation of CDKN2B 3 0.44 1.13 0
135 INT196419 Negative_regulation of Cdkn2b 2 0.12 0.55 0
136 INT348463 Protein_catabolism of RB1 2 0.11 2.22 0
137 INT225170 Regulation of Phosphorylation of RB1 2 0.36 1.12 0
138 INT225167 Negative_regulation of Binding of RB1 2 0.34 1.25 0
139 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0
140 INT196429 Negative_regulation of Gene_expression of Cdkn2b 2 0.27 0.8 0
141 INT284937 Negative_regulation of Positive_regulation of CDKN2B 1 0.37 0.31 0
142 INT271935 Positive_regulation of Phosphorylation of Rps6 1 0.02 0.17 0
143 INT269911 Positive_regulation of Cdkn2b 1 0.31 0 0
144 INT133097 Positive_regulation of Phosphorylation of Tgfb1 1 0.05 0.07 0
145 INT337050 Negative_regulation of Phosphorylation of Rps6 1 0.06 0 0
146 INT260848 Transcription of NBN 1 0.57 0.54 0
147 INT293681 Positive_regulation of Positive_regulation of RB1 1 0.39 0.27 0
148 INT320730 Positive_regulation of Gene_expression of NBN 1 0.60 1.84 0
149 INT293672 Positive_regulation of Transcription of RB1 1 0.45 0.4 0
150 INT254788 Negative_regulation of Regulation of Tgfb1 1 0.06 0.61 0
151 INT293418 Regulation of Binding of HRAS 1 0.01 1.18 0
152 INT260850 Regulation of Gene_expression of NBN 1 0.38 0.57 0
153 INT273783 Regulation of Gene_expression of RB1 1 0.29 0.67 0
154 INT180701 Negative_regulation of Hras 1 0.04 0 0
155 INT169276 Localization of NBN 1 0.08 0.08 0
156 INT254800 Positive_regulation of Phosphorylation of Tgfb1 1 0.04 0.24 0
157 INT284941 Transcription of CDKN2B 1 0.63 1.59 0
158 INT133099 Negative_regulation of Phosphorylation of Tgfb1 1 0.04 0.08 0
159 INT284970 Positive_regulation of Gene_expression of CDKN2B 1 0.61 0.55 0
160 INT133098 Phosphorylation of Tgfb1 1 0.06 0.07 0
161 INT128712 Positive_regulation of Regulation of Tgfb1 1 0.15 0 0
162 INT269886 Binding of Cdkn2b 1 0.23 0.2 0
163 INT147085 Binding of Cdkn2b 1 0.10 0.07 0
164 INT308843 Regulation of Phosphorylation of Rps6 1 0.03 0.16 0
165 INT273522 Negative_regulation of Gene_expression of NBN 1 0.34 0.91 0
166 INT337051 Negative_regulation of Rps6 1 0.06 0.29 0
167 INT284988 Positive_regulation of Transcription of CDKN2B 1 0.44 1.1 0
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