GO:0031577

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Name spindle checkpoint
Categary Process
Go Slim No
Go Link GO:0031577
Unique Molecular Interactions 25
Total Molecular Interactions 26
Total Single Events 524
Pain Genes Associated 3

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for spindle checkpoint. They are ordered first by their pain relevance and then by number of times they were reported for spindle checkpoint. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT182325 TP53 Negative_regulation of Transcription of Birc5 1 0.01 1.34 0.26
2 INT182326 LBR Positive_regulation of Gene_expression of Birc5 1 0.00 0.46 0.17
3 INT302290 Birc5 Regulation of BAK1 1 0.21 1.22 0.07
4 INT302289 Negative_regulation of Birc5 Regulation of BAK1 1 0.20 1.22 0.07
5 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07
6 INT262781 Birc5 Regulation of TEP1 1 0.00 0.49 0.05
7 INT262780 Birc5 Regulation of CD163L1 1 0.00 0.49 0.05
8 INT292505 PTK2 Regulation of Birc5 1 0.29 0.76 0
9 INT292515 LAMB2 Positive_regulation of Birc5 1 0.01 0.7 0
10 INT236246 Binding of CD8A and Birc5 1 0.04 1.34 0
11 INT292512 AKT1 Regulation of Birc5 1 0.08 0.76 0
12 INT239406 Binding of MTTP and TAOK1 1 0.02 0.51 0
13 INT193118 Trp53 Regulation of Gene_expression of Birc5 1 0.19 0.86 0
14 INT237980 CCND3 Regulation of Gene_expression of Birc5 1 0.06 0.96 0
15 INT236241 Binding of Birc5 and Ifna 1 0.05 0.31 0
16 INT187575 TP53 Regulation of Gene_expression of Birc5 1 0.05 1.1 0
17 INT250718 PIK3CB Regulation of Gene_expression of Birc5 1 0.23 0.91 0
18 INT187574 Binding of TP53 and Birc5 1 0.04 1.27 0
19 INT187576 BAX Regulation of Gene_expression of Birc5 1 0.06 1.1 0
20 INT239408 Binding of PADI1 and TAOK1 1 0.01 0.51 0
21 INT249828 Foxm1 Positive_regulation of Transcription of BIRC5 1 0.56 0.12 0
22 INT144042 STAT3 Regulation of Birc5 1 0.47 0.06 0
23 INT193119 Trp53 Regulation of Birc5 1 0.19 0.55 0
24 INT292492 Mlph Regulation of Gene_expression of Birc5 1 0.04 1.11 0
25 INT237979 PPARA Negative_regulation of Birc5 1 0.49 1.26 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for spindle checkpoint. They are ordered first by their pain relevance and then by number of times they were reported in spindle checkpoint. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32
2 INT116464 Negative_regulation of Birc5 53 0.59 45.4 4.91
3 INT182311 Positive_regulation of Birc5 26 0.67 25.32 4.08
4 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74
5 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32
6 INT182318 Regulation of Birc5 25 0.60 23.58 2.29
7 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96
8 INT182317 Binding of Birc5 8 0.32 4.63 0.56
9 INT193108 Negative_regulation of Negative_regulation of Birc5 6 0.42 5.25 0.53
10 INT182315 Positive_regulation of Negative_regulation of Birc5 2 0.45 1.79 0.46
11 INT182314 Transcription of Birc5 4 0.69 2.69 0.37
12 INT182319 Localization of Birc5 6 0.75 5.13 0.34
13 INT311448 Gene_expression of TAOK1 1 0.21 2.47 0.31
14 INT86771 Positive_regulation of TAOK1 2 0.38 4.55 0.29
15 INT311439 Positive_regulation of Gene_expression of TAOK1 1 0.15 1.48 0.18
16 INT193114 Positive_regulation of Positive_regulation of Birc5 1 0.45 0.33 0.17
17 INT193104 Positive_regulation of Regulation of Birc5 1 0.49 1.61 0.15
18 INT182316 Positive_regulation of Localization of Birc5 1 0.02 0.99 0.13
19 INT193106 Phosphorylation of Birc5 3 0.80 2.13 0.09
20 INT250670 Negative_regulation of Phosphorylation of Birc5 2 0.57 1.17 0.09
21 INT193111 Protein_catabolism of Birc5 2 0.86 1.01 0.08
22 INT238499 Negative_regulation of BIRC5 1 0.23 1.66 0.08
23 INT193115 Regulation of Protein_catabolism of Birc5 1 0.44 0.14 0.08
24 INT262749 Negative_regulation of Transcription of Birc5 1 0.02 1.37 0.07
25 INT311444 Binding of TAOK1 1 0.11 0.65 0.05
26 INT208224 Protein_catabolism of TAOK1 1 0.05 0.94 0.04
27 INT249820 Transcription of BIRC5 1 0.67 0.12 0
28 INT249818 Gene_expression of BIRC5 1 0.65 0.12 0
29 INT294807 Regulation of Negative_regulation of Birc5 1 0.45 1.05 0
30 INT249819 Positive_regulation of Gene_expression of BIRC5 1 0.49 0.12 0
31 INT322739 Localization of TAOK1 1 0.02 1.24 0
32 INT249821 Positive_regulation of BIRC5 1 0.45 0.12 0
33 INT250674 Negative_regulation of Positive_regulation of Birc5 1 0.41 1.22 0
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