GO:0031593

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Name polyubiquitin binding
Categary Function
Go Slim No
Go Link GO:0031593
Unique Molecular Interactions 14
Total Molecular Interactions 21
Total Single Events 320
Pain Genes Associated 5

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for polyubiquitin binding. They are ordered first by their pain relevance and then by number of times they were reported for polyubiquitin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT312894 Binding of Gsk3b and Positive_regulation of Gene_expression of Hdac6 1 0.08 1.3 0.27
2 INT312893 Gsk3b Positive_regulation of Hdac6 1 0.07 0.65 0.13
3 INT153740 TNFRSF11A Positive_regulation of Vcp 1 0.04 1.15 0.13
4 INT237085 Binding of Bnip3l and Vcp 1 0.31 3.53 0.05
5 INT220456 Binding of VCAN and BAG6 1 0.01 3.46 0
6 INT320399 Binding of Vcp and Psmb10 1 0.00 0.16 0
7 INT291108 AGL Regulation of Gene_expression of PDK4 1 0.01 0 0
8 INT320400 Binding of Vcp and Khdrbs1 1 0.01 0.07 0
9 INT220455 BAG6 Regulation of INCENP 1 0.00 0.32 0
10 INT220460 VEGFA Regulation of BAG6 1 0.02 1.28 0

Single Events

The table below shows the top 100 pain related interactions that have been reported for polyubiquitin binding. They are ordered first by their pain relevance and then by number of times they were reported in polyubiquitin binding. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2936 Gene_expression of AGL 36 0.49 9.55 3.63
2 INT35745 Negative_regulation of AGL 29 0.50 9.16 2.03
3 INT34140 Negative_regulation of Vcp 2 0.10 0.23 1.32
4 INT220465 Binding of BAG6 7 0.30 6.41 1.07
5 INT5262 Positive_regulation of AGL 14 0.40 7.51 0.65
6 INT76902 Binding of AGL 3 0.02 2.23 0.64
7 INT312882 Negative_regulation of Hdac6 1 0.52 1.86 0.63
8 INT5261 Localization of AGL 10 0.36 3.17 0.61
9 INT23118 Positive_regulation of Gene_expression of AGL 4 0.30 1.74 0.54
10 INT124774 Binding of Vcp 4 0.44 3.4 0.52
11 INT47175 Negative_regulation of Negative_regulation of AGL 4 0.24 1.19 0.36
12 INT123622 Negative_regulation of Vcp 5 0.42 2.51 0.3
13 INT312879 Regulation of Hdac6 1 0.55 0.76 0.29
14 INT312887 Gene_expression of Hdac6 1 0.60 1.28 0.25
15 INT312883 Regulation of Regulation of Hdac6 1 0.40 0.38 0.24
16 INT2935 Negative_regulation of Gene_expression of AGL 4 0.24 2.07 0.23
17 INT123656 Positive_regulation of Localization of AGL 1 0.00 0.26 0.22
18 INT335731 Gene_expression of Vcp 1 0.73 12.21 0.18
19 INT312881 Positive_regulation of Hdac6 1 0.45 0.67 0.15
20 INT16940 Protein_catabolism of AGL 4 0.39 2.94 0.14
21 INT237045 Positive_regulation of Vcp 7 0.62 6.96 0.12
22 INT220472 Gene_expression of BAG6 1 0.11 13.93 0.12
23 INT41285 Regulation of Vcp 1 0.11 0.32 0.1
24 INT107777 Phosphorylation of AGL 3 0.54 2.45 0.09
25 INT107776 Negative_regulation of Phosphorylation of AGL 1 0.37 0.99 0.09
26 INT67258 Positive_regulation of Positive_regulation of AGL 1 0.00 1 0.08
27 INT153679 Regulation of AGL 4 0.04 1.49 0.07
28 INT312877 Positive_regulation of Negative_regulation of Hdac6 1 0.45 0 0.05
29 INT335726 Regulation of Vcp 2 0.22 1.94 0.03
30 INT312888 Phosphorylation of Hdac6 1 0.73 0 0.03
31 INT303847 Positive_regulation of Negative_regulation of AGL 3 0.17 0.61 0
32 INT312873 Negative_regulation of Gene_expression of Hdac6 1 0.38 0 0
33 INT312967 Positive_regulation of Binding of AGL 1 0.03 0.55 0
34 INT312885 Binding of Hdac6 1 0.43 0 0
35 INT312874 Regulation of Phosphorylation of Hdac6 1 0.40 0 0
36 INT312966 Regulation of Gene_expression of AGL 1 0.03 0.27 0
37 INT220466 Regulation of BAG6 1 0.04 1.58 0
38 INT312876 Negative_regulation of Transcription of Hdac6 1 0.38 0 0
39 INT284603 Localization of Vcp 1 0.73 0.82 0
40 INT320418 Binding of Vcp 1 0.14 0.31 0
41 INT335725 Negative_regulation of Gene_expression of Vcp 1 0.55 0.99 0
42 INT320411 Gene_expression of Vcp 1 0.18 0.92 0
43 INT220467 Positive_regulation of Gene_expression of BAG6 1 0.07 1.47 0
44 INT297264 Negative_regulation of Binding of AGL 1 0.01 1.2 0
45 INT335732 Positive_regulation of Gene_expression of Vcp 1 0.57 0.87 0
46 INT312875 Transcription of Hdac6 1 0.61 0 0
47 INT320408 Positive_regulation of Vcp 1 0.15 0.08 0
48 INT220468 Positive_regulation of Binding of BAG6 1 0.07 1.28 0
49 INT312878 Protein_catabolism of Hdac6 1 0.88 0 0
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