GO:0031623

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Name receptor internalization
Categary Process
Go Slim No
Go Link GO:0031623
Unique Molecular Interactions 1172
Total Molecular Interactions 1748
Total Single Events 19961
Pain Genes Associated 63

This page displays the top molecular interactions and top single events that were mentioned in the literature for cytoplasm. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported for receptor internalization. They are ordered first by their pain relevance and then by number of times they were reported for receptor internalization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69886 Ngf Positive_regulation of Calca 8 0.76 2.98 12.77
2 INT166591 Binding of CALCA and DCLK3 4 0.30 0.69 12.18
3 INT180785 Gdnf Positive_regulation of Calca 1 0.23 1.96 8.04
4 INT142177 Calca Positive_regulation of Gene_expression of Igf1 8 0.78 3.57 5.71
5 INT69888 Ngf Positive_regulation of Localization of Calca 4 0.52 0.51 4.95
6 INT102122 Binding of Calca and RT1-M4 7 0.29 5.83 4.94
7 INT11599 Calca Positive_regulation of Npr1 5 0.19 0.3 4.8
8 INT166590 Binding of RAMP1 and DCLK3 2 0.37 0.39 4.8
9 INT24742 Binding of Calca and Vip 1 0.37 0.18 4.68
10 INT296484 Binding of Gria2 and GRIP1 1 0.04 4.52 4.59
11 INT182194 Binding of IL8 and CXCR2 10 0.56 7.14 4.16
12 INT128998 Cxcl1 Positive_regulation of Localization of Calca 1 0.66 2.96 4.15
13 INT13969 Binding of Calca and Sst 3 0.32 0.6 4.02
14 INT13966 Calca Positive_regulation of Localization of Sst 5 0.49 0.75 3.91
15 INT85541 Ngf Positive_regulation of Gene_expression of Calca 2 0.55 1.84 3.71
16 INT87491 CALCA Positive_regulation of Gene_expression of IL8 1 0.72 0.92 3.52
17 INT24710 Binding of Calca and SUB1P1 1 0.01 2.09 3.48
18 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47
19 INT108471 Binding of CALCA and PNOC 1 0.29 0.64 3.25
20 INT69823 Binding of GHR and RYBP 1 0.01 0 3.23
21 INT74159 Ngf Regulation of Gene_expression of Calca 2 0.60 1.66 3.22
22 INT29657 Binding of Calca and Calcb 1 0.26 0 3.16
23 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16
24 INT208572 Binding of IL8 and CXCR1 6 0.33 5.2 3.08
25 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01
26 INT37162 Binding of Calca and Cckar 1 0.04 0.55 3.01
27 INT100835 Binding of Calca and Akap12 1 0.07 0.41 2.92
28 INT166592 Binding of CALCA and RAMP1 2 0.35 0.33 2.91
29 INT73821 CALCA Positive_regulation of Localization of IL8 1 0.25 2.37 2.91
30 INT194409 Binding of CALCA and IGKV1D-8 1 0.15 0 2.84
31 INT169134 Binding of Calca and Trpa1 1 0.37 3.37 2.79
32 INT180779 Bdnf Regulation of Calca 1 0.09 0.23 2.71
33 INT351444 Grin1 Positive_regulation of Gria2 1 0.22 1.5 2.64
34 INT53648 Acot1 Positive_regulation of Localization of Calca 2 0.23 0 2.61
35 INT57624 Calca Regulation of Positive_regulation of Trh 1 0.50 0 2.53
36 INT48526 Binding of Calca and Penk 1 0.24 1.03 2.51
37 INT107322 Positive_regulation of TRPV1 Positive_regulation of Localization of IL8 3 0.13 1.64 2.5
38 INT156799 Gria1 Regulation of Grm8 1 0.11 1.29 2.45
39 INT136129 Calca Positive_regulation of ATP8A2 1 0.38 0.89 2.4
40 INT13967 Calca Positive_regulation of Sst 1 0.45 0 2.3
41 INT152900 TRPV1 Regulation of Gene_expression of CALCA 1 0.69 0.73 2.29
42 INT152901 TRPV1 Regulation of Localization of CALCA 1 0.44 0.73 2.29
43 INT69887 Ngf Regulation of Calca 2 0.49 0.1 2.19
44 INT134583 Arrb2 Regulation of Oprm1 1 0.41 1.23 2.15
45 INT133946 Binding of DNM2 and OPRK1 1 0.11 0 2.1
46 INT79470 Mgat4a Regulation of Localization of Calca 1 0.08 1.72 2.1
47 INT89733 Binding of Calca and Nrm 1 0.31 0.71 2.09
48 INT63873 SRPX Positive_regulation of Localization of Calca 1 0.02 0.49 2.04
49 INT115042 Gdnf Regulation of Calca 1 0.53 0.25 2.03
50 INT26221 Calca Regulation of Gt(pU21)50Imeg 1 0.01 0 2.02
51 INT128996 Ccl2 Positive_regulation of Localization of Calca 1 0.68 1.43 2
52 INT213968 Binding of Calca and Mthfd1 1 0.05 0.16 1.99
53 INT120723 Positive_regulation of Trpv1 Positive_regulation of Localization of Calca 3 0.51 0.48 1.92
54 INT24942 Calca Regulation of TAC1 1 0.13 0.7 1.89
55 INT271408 NGF Positive_regulation of Gene_expression of CALCA 1 0.09 4.89 1.88
56 INT201940 Binding of IL8 and CXCL10 2 0.28 2.46 1.86
57 INT13940 DNM2 Regulation of Localization of CGA 1 0.11 0 1.86
58 INT168723 Positive_regulation of Trpv1 Positive_regulation of Gene_expression of Calca 1 0.48 1.1 1.84
59 INT163514 Ngf Positive_regulation of Gene_expression of Calca 1 0.30 2.21 1.82
60 INT121218 Arrb2 Regulation of Negative_regulation of Prkca 1 0.17 0.23 1.8
61 INT24934 Calca Regulation of Nka1 3 0.05 0.43 1.73
62 INT139156 Binding of Gria1 and Gria2 1 0.23 0.64 1.72
63 INT148090 Binding of CALCA and NCOR2 1 0.00 0.65 1.71
64 INT94617 KNG1 Positive_regulation of Localization of Calca 1 0.00 0.75 1.7
65 INT56134 CALCA Positive_regulation of POMC 2 0.71 0.72 1.68
66 INT102447 Binding of CALCA and CALCRL 2 0.26 0.33 1.67
67 INT145826 Calca Positive_regulation of Gene_expression of Igf1 3 0.75 3.05 1.66
68 INT94618 KNG1 Positive_regulation of Calca 1 0.00 0.75 1.66
69 INT144213 Nppa Positive_regulation of Localization of Calca 1 0.71 2.8 1.65
70 INT23889 Calca Positive_regulation of Localization of Tacr1 1 0.11 0.45 1.65
71 INT24157 Binding of CALCA and SFTPA1 2 0.07 0.96 1.64
72 INT122286 Prkaca Negative_regulation of Negative_regulation of Calca 1 0.12 0.54 1.63
73 INT160578 Binding of CALCA and TAC1 1 0.07 0.91 1.61
74 INT54601 Binding of Mtor and Ache 1 0.20 0.8 1.58
75 INT148935 Ramp1 Regulation of Calca 1 0.27 0.69 1.56
76 INT13968 Calca Negative_regulation of Positive_regulation of Sst 1 0.34 0 1.55
77 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54
78 INT13970 Positive_regulation of Calca Positive_regulation of Sst 1 0.37 0 1.53
79 INT13965 Calca Positive_regulation of Positive_regulation of Sst 1 0.37 0 1.53
80 INT260897 CRH Positive_regulation of Localization of IL8 1 0.24 0.09 1.51
81 INT293013 IL8 Positive_regulation of Positive_regulation of CA2 1 0.12 0.66 1.49
82 INT125845 Positive_regulation of Pag1 Positive_regulation of Gene_expression of Arrb2 1 0.09 0.46 1.48
83 INT96784 Binding of CALCA and Calca 3 0.23 0.27 1.47
84 INT180791 Negative_regulation of Gdnf Regulation of Calca 1 0.17 0 1.47
85 INT180767 Bdnf Positive_regulation of Gene_expression of Calca 1 0.17 0 1.45
86 INT276681 Calca Regulation of Nav1 1 0.07 0.74 1.45
87 INT276686 Calca Regulation of Nav1 1 0.26 0.74 1.45
88 INT169800 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Mapk1 1 0.39 1.04 1.45
89 INT84434 Calca Negative_regulation of Negative_regulation of Hrh1 1 0.06 0.19 1.44
90 INT95325 HTR1B Negative_regulation of Calca 1 0.47 0.69 1.43
91 INT169801 Binding of Adrbk1 and Rapgef3 1 0.34 1.04 1.43
92 INT134760 Ghrl Regulation of Transcription of Calca 1 0.24 2.71 1.42
93 INT298458 Binding of Calcrl and Adarb1 1 0.00 0.23 1.41
94 INT144122 Binding of Calca and P2rx6 1 0.10 0 1.4
95 INT169163 Binding of Calca and Ctbs 1 0.00 0.51 1.4
96 INT51213 Vip Regulation of Localization of Calca 1 0.38 0 1.39
97 INT8719 Npy Negative_regulation of Localization of Calca 1 0.06 0.26 1.39
98 INT133933 Binding of DNM2 and TP53INP2 1 0.00 0 1.38
99 INT168724 Creb1 Negative_regulation of Gene_expression of Calca 1 0.46 1.09 1.38
100 INT168721 Positive_regulation of Creb1 Positive_regulation of Calca 1 0.53 1.07 1.37
101 INT279165 Calca Regulation of Gene_expression of Fdft1 1 0.02 0.41 1.37
102 INT180810 Gopc Positive_regulation of Calca 1 0.02 0.28 1.36
103 INT168722 Creb1 Positive_regulation of Calca 1 0.73 1.05 1.35
104 INT151771 Binding of P2RX3 and Calca 1 0.04 0.89 1.34
105 INT298455 Calca Positive_regulation of Gene_expression of Ceacam3 1 0.17 0.47 1.34
106 INT106839 Arrb2 Regulation of Oprm1 2 0.21 0.44 1.33
107 INT180786 Calca Regulation of Positive_regulation of Ngf 1 0.40 0 1.32
108 INT136603 Calca Positive_regulation of Localization of Il6 1 0.67 0.78 1.32
109 INT180764 Calca Regulation of Positive_regulation of Gdnf 1 0.21 0 1.32
110 INT180807 Calca Regulation of Sorbs1 1 0.02 0 1.32
111 INT180771 Calca Regulation of Positive_regulation of Bdnf 1 0.18 0 1.32
112 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
113 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
114 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
115 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
116 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
117 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
118 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
119 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
120 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
121 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24
122 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
123 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
124 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
125 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
126 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
127 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
128 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
129 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
130 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
131 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
132 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
133 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
134 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
135 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17
136 INT338053 F2r Positive_regulation of Localization of Calca 1 0.06 0.47 1.15
137 INT91394 Negative_regulation of MMP2 Positive_regulation of CALCA 1 0.25 0.15 1.15
138 INT69824 Negative_regulation of Binding of GHR and RYBP 1 0.01 0 1.14
139 INT123387 Binding of Camk2a and Gria2 1 0.13 0.32 1.14
140 INT141979 Calca Negative_regulation of Gene_expression of Il1b 1 0.40 0.62 1.13
141 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12
142 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11
143 INT22176 Calca Regulation of Localization of Prl 4 0.69 0.39 1.11
144 INT4752 Gal Negative_regulation of Localization of Calca 1 0.41 0.06 1.11
145 INT282065 Binding of Calca and Ngf 1 0.14 0.85 1.11
146 INT4753 Sst Negative_regulation of Localization of Calca 1 0.39 0.06 1.1
147 INT70495 CALCA Positive_regulation of CALCB 2 0.40 0 1.08
148 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08
149 INT69889 Ngf Regulation of Localization of Calca 1 0.49 0.1 1.08
150 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08
151 INT296458 Binding of Gria2 and Pick1 3 0.24 1.86 1.07
152 INT91395 MMP2 Positive_regulation of CALCA 1 0.36 0.17 1.07
153 INT79372 Calca Regulation of Pnoc 1 0.34 0 1.07
154 INT10238 Binding of EDN1 and Calca 1 0.00 1.07 1.06
155 INT139225 Calca Negative_regulation of Icam1 1 0.44 1.13 1.06
156 INT296460 Binding of Gria2 and Myo18a 1 0.01 1.49 1.06
157 INT18828 DNM2 Positive_regulation of Localization of LTB4R 1 0.01 0.07 1.06
158 INT139229 Calca Negative_regulation of Cmklr1 1 0.19 1.12 1.06
159 INT139231 Calca Negative_regulation of Timp1 1 0.36 1.11 1.05
160 INT146496 Snta1 Positive_regulation of Gene_expression of Adrbk1 1 0.13 0.73 1.05
161 INT139226 Icam1 Negative_regulation of Calca 1 0.44 1.12 1.05
162 INT146097 Positive_regulation of Binding of Rgs9 and Arrb2 1 0.28 0 1.04
163 INT48260 Binding of Adcyap1 and Calca 1 0.35 0 1.04
164 INT250777 Binding of Cxcl10 and Cxcr1 1 0.14 3.1 1.04
165 INT130167 Trpv1 Regulation of Localization of Calca 2 0.38 0.69 1.03
166 INT86073 Med15 Regulation of Calca 1 0.49 0.2 1.03
167 INT114555 Binding of Calca and St3gal3 1 0.01 0.44 1.03
168 INT146098 Binding of Rgs9 and Arrb2 1 0.19 0 1.03
169 INT101381 POMC Regulation of Localization of IL8 1 0.28 1.49 1.02
170 INT114552 Binding of Calca and Col4a4 1 0.01 0.44 1.02
171 INT51260 Calca Negative_regulation of Nts 1 0.10 0.08 1.01
172 INT293008 IL8 Positive_regulation of Localization of CA2 1 0.11 0.71 1.01
173 INT144661 Dnm1 Negative_regulation of Binding of Hbegf 1 0.24 0 1.01
174 INT51261 Calca Negative_regulation of Sst 1 0.20 0.08 1.01
175 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1
176 INT143916 Arrb2 Regulation of Rbm39 1 0.04 0.18 1
177 INT278946 IL6 Regulation of Gene_expression of IL8 1 0.20 1.9 1
178 INT112163 Calca Positive_regulation of Mpo 1 0.49 1.23 1
179 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1
180 INT162299 Negative_regulation of Adarb1 Negative_regulation of Gene_expression of Calca 1 0.01 0.93 1
181 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98
182 INT94989 Arrb2 Regulation of Regulation of Oprm1 1 0.24 0 0.98
183 INT311102 IL8 Positive_regulation of CXCR7 1 0.00 1.74 0.98
184 INT49163 Binding of Pax3 and Calca 1 0.03 0.37 0.98
185 INT311143 IL8 Positive_regulation of Cxcr1 1 0.04 1.74 0.98
186 INT239539 Binding of CXCR2 and CALCRL 1 0.00 0.38 0.98
187 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96
188 INT24395 Binding of CALCA and CLPP 1 0.03 0.17 0.96
189 INT278940 LEP Positive_regulation of Gene_expression of IL8 1 0.34 1.68 0.96
190 INT111632 Arrb2 Negative_regulation of Regulation of Rbm39 1 0.03 0 0.96
191 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95
192 INT182203 Binding of CXCL1 and CXCR2 1 0.14 1.25 0.95
193 INT148772 Usf1 Regulation of Calca 1 0.40 0.69 0.95
194 INT182190 Binding of IL8 and CXCR4 1 0.26 1.25 0.95
195 INT182207 Binding of CXCR2 and CXCL13 1 0.42 1.26 0.95
196 INT182208 Binding of CXCR2 and CXCL12 1 0.29 1.26 0.95
197 INT180787 Calca Regulation of Gdnf 1 0.18 0.28 0.95
198 INT281085 Binding of Gria2 and Nsf 2 0.26 0.4 0.94
199 INT182193 Binding of CXCR2 and CXCL5 1 0.30 1.25 0.94
200 INT299988 IL6 Positive_regulation of Localization of IL8 1 0.05 0.81 0.94

Single Events

The table below shows the top 100 pain related interactions that have been reported for receptor internalization. They are ordered first by their pain relevance and then by number of times they were reported in receptor internalization. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT2542 Localization of Calca 2008 0.81 518.3 1408.65
2 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84
3 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08
4 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04
5 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38
6 INT2649 Regulation of Calca 433 0.62 146.05 330.95
7 INT10832 Gene_expression of IL8 1050 0.78 698.72 270
8 INT4759 Negative_regulation of Localization of Calca 294 0.59 82.62 226.45
9 INT626 Localization of CALCA 289 0.81 125.39 221.15
10 INT5050 Regulation of Localization of Calca 149 0.62 41.25 148.57
11 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2
12 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47
13 INT2541 Binding of Calca 200 0.48 67.14 134.62
14 INT5008 Localization of Calca 204 0.81 80.35 125.16
15 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75
16 INT12339 Localization of IL8 437 0.81 251.87 117.39
17 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62
18 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61
19 INT5780 Regulation of Gene_expression of Calca 90 0.62 59.52 85.03
20 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37
21 INT1080 Negative_regulation of Ache 343 0.59 108.51 72.4
22 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34
23 INT6761 Binding of CALCA 100 0.48 26.71 62.05
24 INT4760 Negative_regulation of Gene_expression of Calca 93 0.59 34.19 60.3
25 INT4241 Regulation of CALCA 87 0.62 28.19 55.29
26 INT4891 Transcription of Calca 81 0.72 35.27 53.75
27 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66
28 INT8071 Positive_regulation of Gria1 102 0.70 26.61 53.37
29 INT97674 Positive_regulation of Localization of Calca 70 0.69 27.71 51.79
30 INT8490 Negative_regulation of CALCA 87 0.59 29.73 51.34
31 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8
32 INT28265 Positive_regulation of Calca 62 0.70 29.1 41.17
33 INT48222 Positive_regulation of Localization of IL8 123 0.59 78.04 37.2
34 INT8784 Negative_regulation of Positive_regulation of Calca 40 0.59 14.67 33.49
35 INT8746 Negative_regulation of Calca 50 0.59 21.22 33.45
36 INT114173 Phosphorylation of Gria1 27 0.82 33.73 31.24
37 INT49001 Regulation of Gria1 51 0.56 18.28 31.22
38 INT1079 Positive_regulation of Ache 104 0.70 23.52 30.28
39 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21
40 INT64918 Gene_expression of Gria2 108 0.74 29.95 29.67
41 INT23463 Positive_regulation of Gene_expression of CALCA 47 0.70 18.14 28.76
42 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6
43 INT22499 Regulation of Calca 42 0.62 17.32 28.02
44 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98
45 INT2569 Gene_expression of Ache 120 0.78 26.29 26.89
46 INT276 Regulation of Ache 83 0.62 16.75 25.99
47 INT10836 Negative_regulation of IL8 95 0.59 52.59 24.71
48 INT10835 Regulation of IL8 79 0.49 53.04 24.14
49 INT101225 Positive_regulation of Gria2 62 0.64 28.1 23.93
50 INT76249 Gene_expression of Gria1 67 0.75 15.07 22.78
51 INT49623 Negative_regulation of Gria1 39 0.59 12.4 21.59
52 INT8358 Negative_regulation of Localization of CALCA 25 0.59 11.79 21.51
53 INT129987 Phosphorylation of Gria1 63 0.80 20.65 21.02
54 INT52106 Negative_regulation of Localization of IL8 57 0.52 22.81 20.8
55 INT50778 Gene_expression of Adrbk1 24 0.77 11.61 20.73
56 INT54708 Gene_expression of Adrbk1 22 0.75 1.06 20.62
57 INT112930 Negative_regulation of Adrbk1 17 0.58 15.04 20.41
58 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18
59 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46
60 INT28642 Gene_expression of CXCR2 60 0.78 38.69 18.11
61 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83
62 INT22068 Binding of CALCRL 53 0.41 6.14 17.32
63 INT95930 Negative_regulation of Gria2 63 0.56 18.37 17.04
64 INT35998 Positive_regulation of Gene_expression of Calca 31 0.70 16.16 16.98
65 INT10834 Binding of IL8 65 0.48 41.66 16.53
66 INT19071 Localization of Ache 66 0.81 5.1 16.27
67 INT6150 Positive_regulation of Negative_regulation of Calca 20 0.68 4.06 16.26
68 INT62861 Regulation of Gria2 45 0.60 13.35 16.07
69 INT52107 Transcription of IL8 63 0.72 41.66 16.06
70 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73
71 INT42810 Gene_expression of CALCRL 53 0.77 10.87 15.42
72 INT143276 Phosphorylation of Gria2 42 0.80 16.07 15.2
73 INT114172 Positive_regulation of Phosphorylation of Gria1 8 0.63 15.73 14.99
74 INT1284 Negative_regulation of Mmp13 20 0.57 36.21 14.91
75 INT114510 Positive_regulation of Gria2 36 0.57 14.91 14.85
76 INT61864 Regulation of Gene_expression of Gria1 24 0.62 13.27 14.3
77 INT83950 Gene_expression of Cxcr1 31 0.59 27.76 13.91
78 INT49538 Binding of Gria1 22 0.47 2.66 13.35
79 INT123593 Gene_expression of Snca 58 0.78 35.76 12.87
80 INT65109 Negative_regulation of Transcription of Calca 16 0.59 8.63 12.84
81 INT26217 Binding of Calca 22 0.48 5.22 12.57
82 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45
83 INT63104 Negative_regulation of CALCRL 29 0.37 13.62 12.42
84 INT11244 Transcription of CALCA 21 0.69 3.61 12.27
85 INT15136 Regulation of Positive_regulation of Calca 12 0.62 3.02 12.16
86 INT111948 Positive_regulation of Gria1 23 0.61 7.55 12.03
87 INT6151 Negative_regulation of Negative_regulation of Calca 14 0.58 4.86 11.81
88 INT94981 Gene_expression of Arrb2 12 0.70 2.11 11.75
89 INT143098 Negative_regulation of Gene_expression of Adrbk1 9 0.58 8.51 11.37
90 INT66606 Gene_expression of CXCR1 34 0.75 27.79 11.36
91 INT5464 Regulation of CALCRL 24 0.16 4.2 11.19
92 INT259165 Phosphorylation of Gria2 4 0.65 11.65 11.07
93 INT57069 Regulation of Gria2 28 0.44 10.11 11.06
94 INT91357 Regulation of Dnm2 5 0.61 0 11.06
95 INT102448 Gene_expression of RAMP1 23 0.75 4.62 10.9
96 INT5779 Positive_regulation of Transcription of Calca 15 0.62 5.61 10.86
97 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72
98 INT54706 Regulation of Adrbk1 11 0.62 0.89 10.69
99 INT1252 Binding of Ache 46 0.48 9.94 10.25
100 INT85015 Gene_expression of ADM 29 0.73 30.75 10.21
101 INT127123 Positive_regulation of Snca 35 0.70 14.76 10.1
102 INT8072 Localization of Gria1 17 0.75 2.62 10.04
103 INT115614 Binding of Gria2 25 0.43 8.97 9.91
104 INT5465 Positive_regulation of CALCRL 25 0.49 7.24 9.8
105 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71
106 INT96298 Negative_regulation of Gria1 25 0.57 10.61 9.7
107 INT54707 Positive_regulation of Adrbk1 14 0.67 0.51 9.51
108 INT259169 Positive_regulation of Phosphorylation of Gria2 3 0.40 9.98 9.34
109 INT106595 Negative_regulation of Dnm2 10 0.58 0.15 9.29
110 INT123040 Phosphorylation of Grk4 12 0.60 0.31 9.14
111 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86
112 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62
113 INT123382 Gene_expression of Cxcr2 12 0.69 4.62 8.62
114 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54
115 INT8761 Negative_regulation of Binding of Calca 12 0.43 3.59 8.32
116 INT78766 Negative_regulation of Gria2 20 0.52 6.27 8.12
117 INT81345 Gene_expression of ADRBK1 21 0.70 2.89 7.9
118 INT83954 Binding of Cxcr2 21 0.37 17.27 7.65
119 INT14207 Gene_expression of DNM2 20 0.67 5.76 7.64
120 INT25220 Positive_regulation of Binding of Calca 7 0.69 3.78 7.34
121 INT98856 Negative_regulation of Gene_expression of Adrbk1 5 0.56 0.43 7.29
122 INT114509 Transcription of Gria2 10 0.58 0.75 7.27
123 INT83951 Gene_expression of Cxcr2 31 0.71 19.36 7.24
124 INT50779 Positive_regulation of Gene_expression of Adrbk1 9 0.56 2.79 7.23
125 INT57023 Negative_regulation of Gene_expression of Gria1 20 0.58 6.92 7.17
126 INT124264 Regulation of Localization of Calca 10 0.33 1.39 7.14
127 INT106599 Positive_regulation of Dnm2 8 0.69 0.28 7.01
128 INT139149 Binding of Gria1 22 0.37 5.71 6.88
129 INT100079 Positive_regulation of Gene_expression of Arrb2 7 0.63 2.26 6.77
130 INT120298 Negative_regulation of Phosphorylation of Gria1 6 0.57 8.99 6.68
131 INT94979 Regulation of Arrb2 6 0.54 0.51 6.45
132 INT80447 Negative_regulation of ARRB2 5 0.39 3.12 6.3
133 INT168383 Positive_regulation of Mmp13 27 0.67 17.9 6.27
134 INT94986 Positive_regulation of Arrb2 5 0.61 1.3 6.24
135 INT120200 Binding of RAMP1 6 0.47 0.72 6.16
136 INT55034 Positive_regulation of Adm 27 0.61 14.1 6.13
137 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05
138 INT74422 Regulation of Localization of IL8 21 0.62 10.19 5.99
139 INT94927 Transcription of Gria1 12 0.69 3.14 5.94
140 INT54713 Gene_expression of Adrbk2 12 0.65 0.08 5.92
141 INT52813 Regulation of Localization of CALCA 8 0.62 3.16 5.89
142 INT86982 Transcription of Calca 9 0.69 2.98 5.74
143 INT9895 Binding of GHR 18 0.36 4.8 5.65
144 INT75833 Negative_regulation of Positive_regulation of IL8 15 0.53 6.69 5.59
145 INT112102 Regulation of Gene_expression of Gria2 14 0.55 5.4 5.55
146 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54
147 INT57068 Regulation of Gene_expression of Gria2 12 0.36 3.76 5.44
148 INT5778 Regulation of Transcription of Calca 4 0.45 2.47 5.37
149 INT19072 Regulation of Gene_expression of Ache 14 0.62 2.74 5.29
150 INT14715 Negative_regulation of Positive_regulation of CALCA 5 0.43 2.22 5.2
151 INT109246 Gene_expression of Calcrl 16 0.75 4.71 5.19
152 INT135998 Localization of Gria2 18 0.72 3.14 5.15
153 INT85685 Gene_expression of Arrb2 5 0.74 0.66 5.13
154 INT259167 Negative_regulation of Phosphorylation of Gria2 2 0.34 5.24 5.13
155 INT85946 Localization of Gria2 10 0.61 1.23 5.09
156 INT27261 Regulation of Regulation of Calca 7 0.45 2.8 5.08
157 INT26042 Binding of Gria2 20 0.40 4.88 5.04
158 INT75831 Positive_regulation of Transcription of IL8 21 0.63 13.56 4.98
159 INT37148 Negative_regulation of Gene_expression of CALCA 7 0.43 1.91 4.98
160 INT1285 Localization of Mmp13 12 0.78 8.98 4.93
161 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92
162 INT62958 Positive_regulation of CXCR2 14 0.59 8.61 4.92
163 INT99785 Positive_regulation of Cxcr2 10 0.53 8.03 4.89
164 INT20059 Protein_catabolism of Ache 15 0.98 3.73 4.87
165 INT174428 Positive_regulation of Cxcr1 8 0.53 8.1 4.79
166 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71
167 INT85681 Negative_regulation of Arrb2 5 0.47 0.79 4.71
168 INT52251 Negative_regulation of Binding of CALCA 3 0.41 0.57 4.71
169 INT109248 Gene_expression of Ramp1 8 0.72 2.45 4.69
170 INT123594 Negative_regulation of Snca 19 0.59 4.43 4.59
171 INT54987 Regulation of Gene_expression of Calca 6 0.62 3.44 4.59
172 INT88909 Positive_regulation of Gene_expression of Dnm1 6 0.70 3.43 4.59
173 INT1753 Gene_expression of Ache 38 0.78 15.31 4.58
174 INT127122 Positive_regulation of Gene_expression of Snca 11 0.69 15.36 4.56
175 INT106596 Transcription of Dnm2 4 0.69 0 4.5
176 INT115074 Positive_regulation of GRIA1 10 0.67 2.66 4.48
177 INT108935 Transcription of Arrb2 5 0.59 0.5 4.38
178 INT69395 Gene_expression of CNTN2 28 0.68 13.29 4.37
179 INT92797 Regulation of Arrb2 4 0.44 0.81 4.28
180 INT70756 Gene_expression of Adm 28 0.77 13.33 4.22
181 INT129964 Negative_regulation of MMP13 23 0.55 6.48 4.21
182 INT94985 Regulation of Gene_expression of Arrb2 2 0.40 0.43 4.2
183 INT11946 Transcription of Ache 18 0.69 2.62 4.13
184 INT95512 Transcription of Ghr 24 0.69 3.1 4.12
185 INT48784 Gene_expression of GRIA1 12 0.78 3.25 4.11
186 INT92902 Negative_regulation of Positive_regulation of Gria1 6 0.57 1.06 4.1
187 INT88156 Regulation of Gria1 12 0.54 2.5 4.06
188 INT124980 Gene_expression of Cxcr1 2 0.63 7.08 4.06
189 INT100741 Positive_regulation of ADRBK1 10 0.64 1.01 3.95
190 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91
191 INT48786 Phosphorylation of GRIA1 7 0.80 1.89 3.91
192 INT24677 Regulation of Negative_regulation of Calca 6 0.44 0.73 3.9
193 INT129990 Positive_regulation of Phosphorylation of Gria1 11 0.61 3.44 3.87
194 INT119330 Binding of Calcrl 8 0.37 1.96 3.85
195 INT80891 Gene_expression of ADRBK2 6 0.65 0.63 3.83
196 INT85679 Binding of Arrb2 4 0.39 0.79 3.82
197 INT112928 Localization of Dnm2 3 0.74 0 3.81
198 INT102452 Gene_expression of RAMP2 6 0.69 7.11 3.77
199 INT88906 Gene_expression of Dnm1 5 0.78 10.48 3.7
200 INT149614 Localization of MMP13 13 0.81 6.12 3.65
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